Danio rerio

57 known processes

sox9a

SRY-box containing gene 9a

(Aliases: zgc:111921,jef,wu:fj17b12)

sox9a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
skeletal system development GO:0001501 181 1.000
embryonic organ morphogenesis GO:0048562 274 1.000
sensory organ morphogenesis GO:0090596 200 1.000
chordate embryonic development GO:0043009 271 0.999
embryonic viscerocranium morphogenesis GO:0048703 52 0.999
embryonic skeletal system morphogenesis GO:0048704 93 0.999
sensory organ development GO:0007423 393 0.998
skeletal system morphogenesis GO:0048705 102 0.997
Human Mouse
odontogenesis of dentin containing tooth GO:0042475 1 0.996
embryonic organ development GO:0048568 381 0.996
inner ear development GO:0048839 126 0.995
cartilage development GO:0051216 96 0.995
regionalization GO:0003002 274 0.992
Zebrafish
retina morphogenesis in camera type eye GO:0060042 79 0.992
Mouse
heart morphogenesis GO:0003007 156 0.991
Zebrafish Mouse
connective tissue development GO:0061448 99 0.991
embryonic skeletal system development GO:0048706 97 0.990
organic substance biosynthetic process GO:1901576 289 0.988
Human Zebrafish Mouse
regulation of metabolic process GO:0019222 359 0.987
Human Zebrafish Mouse
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.986
Mouse
multicellular organism reproduction GO:0032504 35 0.985
Mouse
enzyme linked receptor protein signaling pathway GO:0007167 106 0.983
Mouse
positive regulation of biological process GO:0048518 253 0.981
Human Zebrafish Mouse
cellular macromolecule metabolic process GO:0044260 391 0.980
Human Zebrafish Mouse
appendage morphogenesis GO:0035107 56 0.979
embryonic cranial skeleton morphogenesis GO:0048701 90 0.978
biosynthetic process GO:0009058 294 0.973
Human Zebrafish Mouse
cartilage morphogenesis GO:0060536 13 0.972
inner ear receptor cell differentiation GO:0060113 29 0.968
Zebrafish
myotube cell development GO:0014904 35 0.967
Mouse
endochondral bone morphogenesis GO:0060350 8 0.967
Human Mouse
rna biosynthetic process GO:0032774 181 0.967
Human Zebrafish Mouse
retina development in camera type eye GO:0060041 146 0.955
Zebrafish Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.948
Human Zebrafish Mouse
regulation of primary metabolic process GO:0080090 311 0.942
Human Zebrafish Mouse
macromolecule biosynthetic process GO:0009059 227 0.941
Human Zebrafish Mouse
digestive tract development GO:0048565 265 0.939
Zebrafish
regulation of chondrocyte differentiation GO:0032330 1 0.938
Human Mouse
blood vessel development GO:0001568 246 0.936
Zebrafish
striated muscle cell differentiation GO:0051146 129 0.933
Mouse
regulation of multicellular organismal process GO:0051239 277 0.927
Human Zebrafish Mouse
signal transduction GO:0007165 455 0.926
Human Mouse
odontogenesis GO:0042476 9 0.923
embryonic limb morphogenesis GO:0030326 2 0.922
regulation of epithelial cell proliferation GO:0050678 3 0.919
Human Mouse
embryonic heart tube development GO:0035050 133 0.916
Zebrafish
neuron development GO:0048666 262 0.911
Zebrafish
determination of left right symmetry GO:0007368 179 0.902
Zebrafish
cellular response to lipid GO:0071396 39 0.900
Human Mouse
periodic partitioning GO:0007365 1 0.897
cellular biosynthetic process GO:0044249 286 0.894
Human Zebrafish Mouse
stem cell differentiation GO:0048863 117 0.892
Human Mouse
eye morphogenesis GO:0048592 144 0.892
Zebrafish Mouse
gene expression GO:0010467 252 0.884
Human Zebrafish Mouse
response to chemical GO:0042221 320 0.883
Human Mouse
cellular macromolecule biosynthetic process GO:0034645 224 0.881
Human Zebrafish Mouse
neuron differentiation GO:0030182 353 0.861
Zebrafish Mouse
chemotaxis GO:0006935 104 0.855
cellular response to growth factor stimulus GO:0071363 39 0.853
Human Mouse
positive regulation of muscle organ development GO:0048636 1 0.848
positive regulation of cellular process GO:0048522 201 0.842
Human Zebrafish Mouse
locomotion GO:0040011 313 0.842
Human Zebrafish Mouse
kidney vasculature development GO:0061440 2 0.839
ear development GO:0043583 127 0.834
cartilage development involved in endochondral bone morphogenesis GO:0060351 8 0.831
Human
morphogenesis of an epithelium GO:0002009 333 0.828
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.827
multicellular organismal reproductive process GO:0048609 35 0.810
Mouse
embryo development ending in birth or egg hatching GO:0009792 271 0.803
cellular response to endogenous stimulus GO:0071495 68 0.799
Human Mouse
hindbrain development GO:0030902 91 0.792
larval development GO:0002164 2 0.783
fin morphogenesis GO:0033334 53 0.773
preganglionic parasympathetic nervous system development GO:0021783 6 0.770
regulation of skeletal muscle tissue development GO:0048641 4 0.764
Mouse
pectoral fin development GO:0033339 50 0.752
organic cyclic compound biosynthetic process GO:1901362 223 0.744
Human Zebrafish Mouse
ossification GO:0001503 23 0.741
Mouse
mesoderm development GO:0007498 88 0.740
Zebrafish
response to corticosteroid GO:0031960 1 0.737
regulation of biological quality GO:0065008 263 0.735
Mouse
otic vesicle development GO:0071599 42 0.722
hair cell differentiation GO:0035315 32 0.720
glomerulus vasculature development GO:0072012 2 0.720
osteoblast differentiation GO:0001649 5 0.718
response to external stimulus GO:0009605 264 0.715
Mouse
dorsal ventral neural tube patterning GO:0021904 1 0.710
cellular response to organic substance GO:0071310 105 0.710
Human Mouse
astrocyte differentiation GO:0048708 1 0.694
muscle fiber development GO:0048747 52 0.693
Mouse
mechanoreceptor differentiation GO:0042490 37 0.691
Zebrafish
positive regulation of macromolecule metabolic process GO:0010604 93 0.684
Human Zebrafish Mouse
bmp signaling pathway GO:0030509 52 0.683
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.681
Human Zebrafish Mouse
appendage development GO:0048736 80 0.671
positive regulation of cellular component movement GO:0051272 11 0.671
Human Mouse
response to growth factor GO:0070848 39 0.666
Human Mouse
photoreceptor cell differentiation GO:0046530 55 0.656
Mouse
female sex differentiation GO:0046660 4 0.653
regulation of rna metabolic process GO:0051252 224 0.645
Human Zebrafish Mouse
reproductive process GO:0022414 40 0.645
Human Mouse
digestive system development GO:0055123 289 0.641
Zebrafish
vasculature development GO:0001944 278 0.640
Zebrafish
regulation of gene expression GO:0010468 265 0.633
Human Zebrafish Mouse
camera type eye photoreceptor cell differentiation GO:0060219 19 0.633
Mouse
nucleobase containing compound biosynthetic process GO:0034654 205 0.632
Human Zebrafish Mouse
somitogenesis GO:0001756 87 0.631
heart development GO:0007507 313 0.631
Zebrafish Mouse
endothelial cell differentiation GO:0045446 20 0.626
Zebrafish
regulation of signal transduction GO:0009966 225 0.625
Mouse
embryonic appendage morphogenesis GO:0035113 30 0.614
organic cyclic compound metabolic process GO:1901360 301 0.613
Human Zebrafish Mouse
neural tube formation GO:0001841 16 0.605
negative regulation of cell communication GO:0010648 96 0.604
Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.598
Human Zebrafish Mouse
ectodermal placode development GO:0071696 37 0.597
pigment cell differentiation GO:0050931 38 0.591
Zebrafish
camera type eye morphogenesis GO:0048593 108 0.589
Mouse
positive regulation of cell communication GO:0010647 56 0.588
Mouse
otic vesicle formation GO:0030916 27 0.586
regulation of reproductive process GO:2000241 4 0.584
Human
developmental process involved in reproduction GO:0003006 27 0.582
Human Mouse
regulation of multicellular organism growth GO:0040014 4 0.582
negative regulation of biological process GO:0048519 304 0.576
Human Mouse
heterocycle biosynthetic process GO:0018130 215 0.571
Human Zebrafish Mouse
neural crest cell development GO:0014032 62 0.561
Mouse
muscle cell development GO:0055001 115 0.559
Mouse
regulation of rna biosynthetic process GO:2001141 213 0.554
Human Zebrafish Mouse
pronephros development GO:0048793 69 0.543
positive regulation of muscle cell differentiation GO:0051149 1 0.540
epithelial cell development GO:0002064 42 0.539
Zebrafish Mouse
gland development GO:0048732 143 0.538
Human Zebrafish Mouse
multicellular organism growth GO:0035264 4 0.538
camera type eye development GO:0043010 222 0.537
Zebrafish Mouse
tissue migration GO:0090130 37 0.531
Human Mouse
regulation of signaling GO:0023051 235 0.529
Mouse
forebrain neuron development GO:0021884 7 0.528
retina layer formation GO:0010842 24 0.527
response to glucocorticoid GO:0051384 1 0.527
cell projection organization GO:0030030 284 0.527
meiotic nuclear division GO:0007126 4 0.524
cellular nitrogen compound metabolic process GO:0034641 290 0.521
Human Zebrafish Mouse
cellular response to chemical stimulus GO:0070887 157 0.512
Human Mouse
myotube differentiation GO:0014902 45 0.508
Mouse
developmental pigmentation GO:0048066 48 0.508
Zebrafish
neural retina development GO:0003407 49 0.508
Mouse
patterning of blood vessels GO:0001569 15 0.504
angiogenesis GO:0001525 158 0.501
central nervous system development GO:0007417 387 0.500
inner ear morphogenesis GO:0042472 63 0.496
cellular component movement GO:0006928 335 0.496
Human Zebrafish Mouse
growth plate cartilage development GO:0003417 2 0.496
oligodendrocyte differentiation GO:0048709 23 0.495
response to decreased oxygen levels GO:0036293 25 0.491
negative regulation of signaling GO:0023057 96 0.483
Mouse
renal system vasculature development GO:0061437 2 0.482
positive regulation of nucleic acid templated transcription GO:1903508 57 0.474
Human Zebrafish Mouse
regulation of ossification GO:0030278 5 0.471
Mouse
neural crest cell differentiation GO:0014033 72 0.466
Mouse
blood vessel morphogenesis GO:0048514 216 0.465
Zebrafish
regulation of biosynthetic process GO:0009889 250 0.462
Human Zebrafish Mouse
localization of cell GO:0051674 244 0.456
Human Zebrafish Mouse
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.456
Human Mouse
neural crest cell migration GO:0001755 42 0.455
positive regulation of muscle tissue development GO:1901863 1 0.454
defense response GO:0006952 47 0.453
retinal ganglion cell axon guidance GO:0031290 35 0.451
response to hormone GO:0009725 48 0.450
smooth muscle tissue development GO:0048745 1 0.449
Mouse
regulation of bmp signaling pathway GO:0030510 39 0.444
regulation of endothelial cell proliferation GO:0001936 1 0.443
primary neural tube formation GO:0014020 1 0.442
neuron projection guidance GO:0097485 86 0.440
cell migration GO:0016477 237 0.440
Human Zebrafish Mouse
auditory receptor cell fate commitment GO:0009912 4 0.440
trigeminal nerve development GO:0021559 3 0.432
hypothalamus cell differentiation GO:0021979 4 0.429
cardiocyte differentiation GO:0035051 44 0.426
muscle cell differentiation GO:0042692 139 0.424
Mouse
positive regulation of metabolic process GO:0009893 108 0.422
Human Zebrafish Mouse
regulation of skeletal muscle fiber development GO:0048742 2 0.417
Mouse
endodermal cell fate determination GO:0007493 2 0.410
Zebrafish
positive regulation of signaling GO:0023056 56 0.408
Mouse
brain development GO:0007420 293 0.408
otic vesicle morphogenesis GO:0071600 34 0.398
determination of heart left right asymmetry GO:0061371 117 0.387
Zebrafish
positive regulation of signal transduction GO:0009967 56 0.386
Mouse
ear morphogenesis GO:0042471 64 0.386
extracellular structure organization GO:0043062 27 0.382
Mouse
forebrain development GO:0030900 96 0.382
auditory receptor cell differentiation GO:0042491 15 0.379
carbohydrate metabolic process GO:0005975 12 0.379
hematopoietic or lymphoid organ development GO:0048534 191 0.377
gamete generation GO:0007276 33 0.377
Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.377
Human Zebrafish Mouse
regulation of cell communication GO:0010646 232 0.371
Mouse
glucose homeostasis GO:0042593 1 0.370
cell projection morphogenesis GO:0048858 244 0.370
negative regulation of response to stimulus GO:0048585 104 0.370
Mouse
skeletal muscle tissue development GO:0007519 67 0.369
Mouse
olfactory bulb development GO:0021772 4 0.361
aging GO:0007568 2 0.358
motor neuron axon guidance GO:0008045 23 0.348
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.347
extracellular matrix organization GO:0030198 27 0.346
Mouse
muscle organ development GO:0007517 101 0.343
Mouse
palate development GO:0060021 8 0.343
Zebrafish
limb morphogenesis GO:0035108 7 0.341
Mouse
regulation of muscle organ development GO:0048634 9 0.337
Mouse
bmp signaling pathway involved in heart development GO:0061312 15 0.336
cell death GO:0008219 121 0.336
Human Mouse
neuron projection development GO:0031175 180 0.331
cellular aromatic compound metabolic process GO:0006725 295 0.323
Human Zebrafish Mouse
positive regulation of cellular metabolic process GO:0031325 94 0.322
Human Zebrafish Mouse
neural tube development GO:0021915 62 0.321
regulation of transcription dna templated GO:0006355 213 0.316
Human Zebrafish Mouse
response to vitamin GO:0033273 3 0.314
determination of bilateral symmetry GO:0009855 204 0.314
Zebrafish
skin development GO:0043588 54 0.313
Mouse
response to organic substance GO:0010033 153 0.313
Human Mouse
regulation of multicellular organismal development GO:2000026 223 0.310
Human Zebrafish Mouse
limb bud formation GO:0060174 2 0.309
Mouse
cellular response to hormone stimulus GO:0032870 39 0.304
response to bacterium GO:0009617 58 0.299
oxoacid metabolic process GO:0043436 31 0.294
cranial suture morphogenesis GO:0060363 1 0.290
negative regulation of cellular process GO:0048523 283 0.288
Human Mouse
cartilage condensation GO:0001502 3 0.287
Mouse
aromatic compound biosynthetic process GO:0019438 217 0.284
Human Zebrafish Mouse
cardioblast differentiation GO:0010002 9 0.283
cellular response to organic cyclic compound GO:0071407 38 0.283
rhombomere development GO:0021546 19 0.283
positive regulation of striated muscle cell differentiation GO:0051155 1 0.281
bmp signaling pathway involved in heart jogging GO:0003303 14 0.276
regulation of protein catabolic process GO:0042176 1 0.275
Mouse
negative regulation of muscle organ development GO:0048635 5 0.273
muscle structure development GO:0061061 196 0.273
Mouse
apoptotic process involved in development GO:1902742 2 0.271
generation of neurons GO:0048699 385 0.269
Zebrafish Mouse
negative regulation of axon guidance GO:1902668 1 0.269
cell part morphogenesis GO:0032990 246 0.266
eye development GO:0001654 277 0.265
Zebrafish Mouse
striated muscle tissue development GO:0014706 110 0.264
Mouse
negative regulation of endothelial cell migration GO:0010596 1 0.264
programmed cell death GO:0012501 119 0.259
Human Mouse
definitive hemopoiesis GO:0060216 18 0.253
endocardium formation GO:0060214 1 0.251
regulation of vasculature development GO:1901342 33 0.248
regulation of developmental process GO:0050793 247 0.247
Human Zebrafish Mouse
regulation of organ growth GO:0046620 3 0.247
negative regulation of transcription dna templated GO:0045892 45 0.241
Human Mouse
anterior commissure morphogenesis GO:0021960 3 0.241
hormone metabolic process GO:0042445 19 0.241
olfactory lobe development GO:0021988 4 0.239
endochondral bone growth GO:0003416 2 0.239
neuron projection morphogenesis GO:0048812 161 0.238
apoptotic process GO:0006915 116 0.235
Human Mouse
response to abiotic stimulus GO:0009628 122 0.232
Mouse
vasculogenesis GO:0001570 41 0.231
Zebrafish
androgen metabolic process GO:0008209 2 0.230
smoothened signaling pathway GO:0007224 30 0.228
rhombomere morphogenesis GO:0021593 17 0.227
glycosaminoglycan biosynthetic process GO:0006024 8 0.226
tube morphogenesis GO:0035239 349 0.226
Zebrafish Mouse
branchiomotor neuron axon guidance GO:0021785 1 0.225
positive regulation of skeletal muscle tissue development GO:0048643 1 0.221
foregut morphogenesis GO:0007440 4 0.219
somatic stem cell maintenance GO:0035019 1 0.219
Mouse
epithelial cell morphogenesis GO:0003382 2 0.219
cellular hormone metabolic process GO:0034754 19 0.218
eye photoreceptor cell development GO:0042462 30 0.217
endothelium development GO:0003158 25 0.217
Zebrafish
cranial nerve development GO:0021545 42 0.214
negative regulation of striated muscle tissue development GO:0045843 2 0.214
establishment of protein localization to organelle GO:0072594 4 0.213
wound healing GO:0042060 90 0.210
Zebrafish
nuclear transport GO:0051169 4 0.210
peripheral nervous system neuron differentiation GO:0048934 28 0.210
negative regulation of gene expression GO:0010629 65 0.209
Human Mouse
oligodendrocyte cell fate specification GO:0021778 4 0.207
single organism metabolic process GO:0044710 217 0.205
Mouse
dorsal ventral pattern formation GO:0009953 125 0.204
Zebrafish
kidney vasculature morphogenesis GO:0061439 1 0.204
cellular response to nutrient levels GO:0031669 2 0.202
otic placode formation GO:0043049 23 0.200
response to nutrient GO:0007584 3 0.198
thyroid gland development GO:0030878 12 0.197
polarized epithelial cell differentiation GO:0030859 4 0.196
axis specification GO:0009798 43 0.196
Zebrafish
cranial nerve morphogenesis GO:0021602 15 0.196
neuromast development GO:0048884 46 0.194
head development GO:0060322 303 0.194
female gonad development GO:0008585 4 0.193
larval heart development GO:0007508 2 0.193
nerve development GO:0021675 45 0.190
apoptotic process involved in morphogenesis GO:0060561 2 0.190
er nucleus signaling pathway GO:0006984 2 0.189
limb development GO:0060173 8 0.186
Mouse
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.183
notochord development GO:0030903 54 0.182
Mouse
striated muscle cell development GO:0055002 108 0.181
Mouse
regulation of stem cell proliferation GO:0072091 2 0.179
Mouse
sensory system development GO:0048880 76 0.179
dorsal ventral axis specification GO:0009950 14 0.179
Zebrafish
regulation of wnt signaling pathway GO:0030111 53 0.178
Mouse
proteoglycan metabolic process GO:0006029 14 0.177
response to organic cyclic compound GO:0014070 51 0.177
nucleocytoplasmic transport GO:0006913 4 0.177
endodermal cell fate specification GO:0001714 17 0.176
Zebrafish
swim bladder morphogenesis GO:0048795 4 0.176
anterior posterior axon guidance GO:0033564 5 0.174
ameboidal type cell migration GO:0001667 143 0.174
Human Zebrafish Mouse
cell fate specification GO:0001708 68 0.173
Zebrafish Mouse
multicellular organismal metabolic process GO:0044236 2 0.172
mitotic cell cycle GO:0000278 64 0.172
head morphogenesis GO:0060323 8 0.170
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.169
embryonic heart tube morphogenesis GO:0003143 108 0.169
epidermal cell differentiation GO:0009913 36 0.169
nephron morphogenesis GO:0072028 2 0.167
Mouse
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.165
positive regulation of epithelial cell differentiation GO:0030858 2 0.165
Mouse
thymus development GO:0048538 10 0.164
hormone biosynthetic process GO:0042446 3 0.163
bone development GO:0060348 14 0.163
Human Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.162
Human Zebrafish Mouse
anterior posterior pattern specification GO:0009952 152 0.161
chemical homeostasis GO:0048878 49 0.161
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.159
Human Mouse
positive regulation of response to stimulus GO:0048584 80 0.158
Mouse
neuromast hair cell development GO:0035675 6 0.157
single organism nuclear import GO:1902593 3 0.156
single organism transport GO:0044765 206 0.153
organ formation GO:0048645 17 0.153
Zebrafish
eye photoreceptor cell differentiation GO:0001754 45 0.152
Mouse
embryonic epithelial tube formation GO:0001838 17 0.150
Mouse
axon development GO:0061564 166 0.150
regulation of bone mineralization GO:0030500 2 0.150
Mouse
regulation of anatomical structure morphogenesis GO:0022603 130 0.148
Zebrafish Mouse
endothelial cell proliferation GO:0001935 11 0.148
stem cell division GO:0017145 1 0.148
forebrain regionalization GO:0021871 4 0.148
regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 8 0.146
posterior lateral line nerve development GO:0048918 8 0.146
organ growth GO:0035265 12 0.145
Mouse
female gamete generation GO:0007292 14 0.145
regulation of myotube differentiation GO:0010830 2 0.144
Mouse
endocardium development GO:0003157 9 0.141
negative regulation of epithelial cell migration GO:0010633 1 0.139
axonogenesis GO:0007409 152 0.139
bone morphogenesis GO:0060349 11 0.139
Human Mouse
lipid biosynthetic process GO:0008610 22 0.138
regulation of mesenchymal cell proliferation GO:0010464 1 0.138
Mouse
photoreceptor cell development GO:0042461 40 0.136
glomerular epithelial cell fate commitment GO:0072314 4 0.132
reproduction GO:0000003 40 0.132
Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.131
Human Mouse
positive regulation of programmed cell death GO:0043068 29 0.128
negative regulation of biosynthetic process GO:0009890 55 0.128
Human Mouse
cell surface receptor signaling pathway GO:0007166 325 0.128
Mouse
response to drug GO:0042493 3 0.126
response to metal ion GO:0010038 34 0.125
regulation of nitrogen compound metabolic process GO:0051171 251 0.125
Human Zebrafish Mouse
direct ossification GO:0036072 3 0.125
regulation of response to stimulus GO:0048583 269 0.125
Mouse
negative regulation of signal transduction GO:0009968 94 0.124
Mouse
posterior lateral line neuromast hair cell differentiation GO:0048923 8 0.124
negative regulation of smoothened signaling pathway GO:0045879 6 0.123
response to biotic stimulus GO:0009607 97 0.123
response to endogenous stimulus GO:0009719 83 0.121
Human Mouse
post embryonic organ development GO:0048569 4 0.119
multi organism process GO:0051704 134 0.119
Mouse
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 1 0.117
regulation of cartilage development GO:0061035 7 0.117
Human Zebrafish Mouse
inner ear receptor cell fate commitment GO:0060120 4 0.117
protein complex subunit organization GO:0071822 46 0.117
Human
lipid storage GO:0019915 1 0.115
digestive tract morphogenesis GO:0048546 231 0.114
Zebrafish
regulation of transcription involved in cell fate commitment GO:0060850 1 0.114
response to lipid GO:0033993 60 0.114
Human Mouse
positive regulation of endothelial cell differentiation GO:0045603 2 0.113
embryonic skeletal joint development GO:0072498 3 0.113
segment polarity determination GO:0007367 1 0.112
morphogenesis of embryonic epithelium GO:0016331 30 0.110
Mouse
epithelial tube morphogenesis GO:0060562 148 0.109
Mouse
sensory perception of mechanical stimulus GO:0050954 16 0.109
regulation of macromolecule biosynthetic process GO:0010556 225 0.109
Human Zebrafish Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 9 0.108
Zebrafish
positive regulation of multicellular organismal process GO:0051240 52 0.107
Human Mouse
regulation of growth GO:0040008 42 0.107
protein targeting to nucleus GO:0044744 3 0.107
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.105
glial cell migration GO:0008347 3 0.104
neuron fate specification GO:0048665 20 0.104
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.104
Zebrafish
skeletal muscle organ development GO:0060538 78 0.104
Mouse
hemopoiesis GO:0030097 183 0.104
embryonic camera type eye development GO:0031076 29 0.104
glial cell differentiation GO:0010001 42 0.104
positive regulation of rna metabolic process GO:0051254 59 0.103
Human Zebrafish Mouse
heart looping GO:0001947 94 0.102
peripheral nervous system neuron development GO:0048935 22 0.099
peripheral nervous system development GO:0007422 55 0.098
Zebrafish
positive regulation of apoptotic process GO:0043065 29 0.098
negative regulation of transcription elongation from rna polymerase ii promoter GO:0034244 1 0.098
regulation of locomotion GO:0040012 55 0.096
Human Mouse
wnt signaling pathway GO:0016055 80 0.096
Mouse
nitrogen compound metabolic process GO:0006807 319 0.095
Human Zebrafish Mouse
protein import GO:0017038 3 0.095
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.092
Human Mouse
epithelium migration GO:0090132 25 0.092
Human Mouse
autophagy GO:0006914 4 0.091
development of primary female sexual characteristics GO:0046545 4 0.091
cellular protein localization GO:0034613 20 0.091
Mouse
stem cell development GO:0048864 82 0.090
Mouse
determination of intestine left right asymmetry GO:0071908 2 0.090
organic acid metabolic process GO:0006082 31 0.090
sensory neuron axon guidance GO:0097374 3 0.089
cellular component morphogenesis GO:0032989 336 0.088
Mouse
renal system vasculature morphogenesis GO:0061438 1 0.087
rhombomere boundary formation GO:0021654 10 0.087
negative regulation of reproductive process GO:2000242 3 0.087
regulation of blood circulation GO:1903522 32 0.085
regulation of embryonic development GO:0045995 47 0.085
Zebrafish
negative regulation of muscle cell differentiation GO:0051148 1 0.085
Mouse
distal tubule development GO:0072017 1 0.084
embryonic pectoral fin morphogenesis GO:0035118 24 0.084
epithelial cell differentiation GO:0030855 116 0.083
Zebrafish Mouse
protein import into nucleus GO:0006606 3 0.083
central nervous system neuron development GO:0021954 29 0.083
regulation of cardiac muscle cell differentiation GO:2000725 1 0.083
positive regulation of cellular protein metabolic process GO:0032270 22 0.082
Mouse
protein metabolic process GO:0019538 183 0.082
Mouse
glial cell fate specification GO:0021780 4 0.082
face morphogenesis GO:0060325 6 0.081
transport GO:0006810 220 0.081
positive regulation of striated muscle tissue development GO:0045844 1 0.081
carboxylic acid metabolic process GO:0019752 22 0.081
negative regulation of cellular metabolic process GO:0031324 77 0.080
Human Mouse
proteoglycan biosynthetic process GO:0030166 12 0.080
body morphogenesis GO:0010171 16 0.080
negative regulation of nucleic acid templated transcription GO:1903507 45 0.079
Human Mouse
regulation of epithelial cell migration GO:0010632 5 0.079
Human Mouse
aminoglycan biosynthetic process GO:0006023 8 0.078
regulation of transport GO:0051049 45 0.077
regulation of cell death GO:0010941 103 0.077
Human Mouse
neuromast hair cell differentiation GO:0048886 12 0.076
mucopolysaccharide metabolic process GO:1903510 2 0.075
negative regulation of endodermal cell fate specification GO:0042664 8 0.075
response to other organism GO:0051707 97 0.075
sexual reproduction GO:0019953 36 0.074
Mouse
mechanosensory lateral line system development GO:0048881 49 0.073
regulation of vascular permeability GO:0043114 5 0.073
carbohydrate homeostasis GO:0033500 1 0.073
ovulation cycle GO:0042698 2 0.073
oogenesis GO:0048477 14 0.072
response to retinoic acid GO:0032526 6 0.072
Human Mouse
cellular response to molecule of bacterial origin GO:0071219 3 0.072
specification of organ identity GO:0010092 2 0.072
response to hexose GO:0009746 3 0.072
sprouting angiogenesis GO:0002040 53 0.071
regulation of programmed cell death GO:0043067 101 0.071
Human Mouse
multicellular organismal homeostasis GO:0048871 29 0.071
Mouse
lipid catabolic process GO:0016042 4 0.071
regulation of cellular component organization GO:0051128 86 0.070
Mouse
floor plate formation GO:0021508 12 0.069
posterior lateral line nerve glial cell morphogenesis involved in differentiation GO:0048942 5 0.069
specification of symmetry GO:0009799 204 0.069
Zebrafish
vascular endothelial growth factor receptor signaling pathway GO:0048010 13 0.068
protein complex assembly GO:0006461 30 0.068
Human
embryonic foregut morphogenesis GO:0048617 1 0.068
response to inorganic substance GO:0010035 38 0.068
cardiogenic plate morphogenesis GO:0003142 1 0.067
regulation of cellular component biogenesis GO:0044087 12 0.067
Mouse
retinoic acid receptor signaling pathway GO:0048384 16 0.067
regulation of binding GO:0051098 3 0.066
positive regulation of neuron death GO:1901216 1 0.066
macromolecular complex subunit organization GO:0043933 74 0.066
Human
myelination of posterior lateral line nerve axons GO:0048932 5 0.065
histone deacetylation GO:0016575 2 0.065
positive regulation of cellular component biogenesis GO:0044089 3 0.065
Mouse
cardioblast migration to the midline involved in heart field formation GO:0060975 7 0.065
Zebrafish
regulation of heart growth GO:0060420 2 0.064
positive regulation of transcription dna templated GO:0045893 57 0.064
Human Zebrafish Mouse
post embryonic morphogenesis GO:0009886 4 0.063
death GO:0016265 121 0.063
Human Mouse
regulation of biomineral tissue development GO:0070167 2 0.063
Mouse
forebrain dorsal ventral pattern formation GO:0021798 1 0.063
negative regulation of epithelial cell proliferation GO:0050680 1 0.063
Mouse
regulation of striated muscle cell differentiation GO:0051153 6 0.062
Mouse

sox9a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
osteochondrodysplasia DOID:2256 0 0.428
Human
bone development disease DOID:0080006 0 0.428
Human
bone disease DOID:0080001 0 0.428
Human
disease of anatomical entity DOID:7 0 0.428
Human
musculoskeletal system disease DOID:17 0 0.428
Human
connective tissue disease DOID:65 0 0.428
Human