Danio rerio

0 known processes

spcs2

signal peptidase complex subunit 2 homolog (S. cerevisiae)

(Aliases: wu:fa12g08,zgc:110364)

spcs2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.385
Worm
heart development GO:0007507 313 0.114
cellular nitrogen compound metabolic process GO:0034641 290 0.099
regionalization GO:0003002 274 0.094
multicellular organism growth GO:0035264 4 0.092
cellular macromolecule metabolic process GO:0044260 391 0.070
embryo development ending in birth or egg hatching GO:0009792 271 0.067
Worm
tube morphogenesis GO:0035239 349 0.066
chordate embryonic development GO:0043009 271 0.062
response to chemical GO:0042221 320 0.060
cellular component morphogenesis GO:0032989 336 0.055
gastrulation GO:0007369 208 0.055
response to stress GO:0006950 263 0.050
cell part morphogenesis GO:0032990 246 0.050
embryonic organ development GO:0048568 381 0.050
regulation of multicellular organism growth GO:0040014 4 0.048
aging GO:0007568 2 0.048
single organism localization GO:1902578 225 0.048
nitrogen compound metabolic process GO:0006807 319 0.048
organelle organization GO:0006996 227 0.047
cellular aromatic compound metabolic process GO:0006725 295 0.046
regulation of signal transduction GO:0009966 225 0.046
somite development GO:0061053 96 0.046
regulation of metabolic process GO:0019222 359 0.046
regulation of primary metabolic process GO:0080090 311 0.045
signal transduction GO:0007165 455 0.044
biosynthetic process GO:0009058 294 0.044
organic substance biosynthetic process GO:1901576 289 0.042
establishment of localization GO:0051234 244 0.042
Worm
purine nucleoside monophosphate catabolic process GO:0009128 4 0.042
regulation of macromolecule metabolic process GO:0060255 317 0.042
anterior posterior pattern specification GO:0009952 152 0.041
regulation of cellular metabolic process GO:0031323 320 0.041
cognition GO:0050890 1 0.041
cell morphogenesis GO:0000902 289 0.041
tube closure GO:0060606 1 0.041
ribonucleoside monophosphate catabolic process GO:0009158 4 0.040
regulation of response to stimulus GO:0048583 269 0.040
morphogenesis of an epithelium GO:0002009 333 0.040
small molecule metabolic process GO:0044281 77 0.040
cellular biosynthetic process GO:0044249 286 0.039
gene expression GO:0010467 252 0.039
regulation of nucleotide catabolic process GO:0030811 2 0.039
nucleobase containing compound metabolic process GO:0006139 274 0.039
cellular amine metabolic process GO:0044106 2 0.039
negative regulation of biological process GO:0048519 304 0.039
localization of cell GO:0051674 244 0.038
organonitrogen compound metabolic process GO:1901564 74 0.038
positive regulation of cellular component biogenesis GO:0044089 3 0.038
protein metabolic process GO:0019538 183 0.037
maintenance of location GO:0051235 4 0.037
cell projection organization GO:0030030 284 0.036
guanosine containing compound catabolic process GO:1901069 2 0.036
somitogenesis GO:0001756 87 0.036
heart morphogenesis GO:0003007 156 0.036
negative regulation of cellular process GO:0048523 283 0.034
organic cyclic compound metabolic process GO:1901360 301 0.034
digestive tract morphogenesis GO:0048546 231 0.034
cellular component biogenesis GO:0044085 178 0.033
rna metabolic process GO:0016070 219 0.033
regulation of signaling GO:0023051 235 0.033
single organism organelle organization GO:1902589 199 0.032
macromolecule biosynthetic process GO:0009059 227 0.032
neuron development GO:0048666 262 0.032
atp catabolic process GO:0006200 4 0.032
synaptic growth at neuromuscular junction GO:0051124 2 0.032
single organism metabolic process GO:0044710 217 0.032
regulation of nucleoside metabolic process GO:0009118 2 0.031
digestive system development GO:0055123 289 0.031
response to drug GO:0042493 3 0.031
generation of neurons GO:0048699 385 0.031
protein modification process GO:0036211 100 0.031
heterocycle metabolic process GO:0046483 290 0.030
regulation of nitrogen compound metabolic process GO:0051171 251 0.030
positive regulation of cell cycle GO:0045787 3 0.030
primary neural tube formation GO:0014020 1 0.030
regulation of purine nucleotide catabolic process GO:0033121 2 0.029
transport GO:0006810 220 0.029
Worm
developmental growth GO:0048589 166 0.029
nucleoside monophosphate catabolic process GO:0009125 4 0.029
regulation of developmental process GO:0050793 247 0.027
regulation of molecular function GO:0065009 70 0.027
lipid storage GO:0019915 1 0.027
carbohydrate derivative metabolic process GO:1901135 61 0.027
meiotic nuclear division GO:0007126 4 0.027
phosphorus metabolic process GO:0006793 109 0.027
cellular localization GO:0051641 97 0.026
cellular ketone metabolic process GO:0042180 11 0.026
oxoacid metabolic process GO:0043436 31 0.026
positive regulation of biological process GO:0048518 253 0.026
regulation of protein complex assembly GO:0043254 3 0.026
regulation of multicellular organismal process GO:0051239 277 0.026
determination of left right symmetry GO:0007368 179 0.026
establishment of protein localization to plasma membrane GO:0090002 1 0.026
positive regulation of protein complex assembly GO:0031334 2 0.026
sensory organ development GO:0007423 393 0.025
cellular component assembly GO:0022607 170 0.025
response to organic substance GO:0010033 153 0.025
hemopoiesis GO:0030097 183 0.025
positive regulation of transport GO:0051050 2 0.025
determination of bilateral symmetry GO:0009855 204 0.025
single organism transport GO:0044765 206 0.024
cellular response to organic substance GO:0071310 105 0.024
phosphate containing compound metabolic process GO:0006796 108 0.023
growth GO:0040007 174 0.023
neuron differentiation GO:0030182 353 0.023
recombinational repair GO:0000725 1 0.023
cell projection morphogenesis GO:0048858 244 0.023
amine metabolic process GO:0009308 2 0.023
regulation of cellular amino acid metabolic process GO:0006521 0 0.023
guanosine containing compound metabolic process GO:1901068 4 0.022
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.022
gtp metabolic process GO:0046039 4 0.022
regulation of multicellular organismal development GO:2000026 223 0.022
cellular response to external stimulus GO:0071496 2 0.022
cellular protein metabolic process GO:0044267 129 0.022
cell migration GO:0016477 237 0.022
response to topologically incorrect protein GO:0035966 2 0.022
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.022
cellular component movement GO:0006928 335 0.022
regulation of gtp catabolic process GO:0033124 2 0.021
digestive tract development GO:0048565 265 0.021
embryonic organ morphogenesis GO:0048562 274 0.021
protein localization to plasma membrane GO:0072659 1 0.021
cellular macromolecule biosynthetic process GO:0034645 224 0.021
regulation of biological quality GO:0065008 263 0.021
cell substrate adhesion GO:0031589 4 0.021
immune system process GO:0002376 241 0.021
er nucleus signaling pathway GO:0006984 2 0.021
negative regulation of catabolic process GO:0009895 3 0.020
chemosensory behavior GO:0007635 1 0.020
multi organism process GO:0051704 134 0.020
regulation of catalytic activity GO:0050790 55 0.020
immune system development GO:0002520 191 0.020
embryonic heart tube development GO:0035050 133 0.020
nucleocytoplasmic transport GO:0006913 4 0.020
regulation of cell communication GO:0010646 232 0.020
regulation of cellular amine metabolic process GO:0033238 0 0.020
cilium morphogenesis GO:0060271 85 0.020
cell surface receptor signaling pathway GO:0007166 325 0.020
regulation of rna biosynthetic process GO:2001141 213 0.020
rna localization GO:0006403 4 0.019
specification of symmetry GO:0009799 204 0.019
organic acid metabolic process GO:0006082 31 0.019
macromolecule modification GO:0043412 111 0.019
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.019
stem cell proliferation GO:0072089 4 0.019
protein import into nucleus GO:0006606 3 0.019
axis specification GO:0009798 43 0.019
behavior GO:0007610 74 0.019
regulation of establishment of protein localization GO:0070201 4 0.019
gtp catabolic process GO:0006184 2 0.018
regulation of translational initiation GO:0006446 1 0.018
epithelial tube morphogenesis GO:0060562 148 0.018
phosphorylation GO:0016310 69 0.018
locomotion GO:0040011 313 0.018
Worm
protein targeting to nucleus GO:0044744 3 0.018
system process GO:0003008 185 0.018
cellular response to chemical stimulus GO:0070887 157 0.018
cellular response to nutrient levels GO:0031669 2 0.018
regulation of gene expression GO:0010468 265 0.018
rna biosynthetic process GO:0032774 181 0.017
segmentation GO:0035282 97 0.017
regulation of cell activation GO:0050865 1 0.017
modification dependent macromolecule catabolic process GO:0043632 3 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.017
cellular nitrogen compound biosynthetic process GO:0044271 218 0.017
regulation of binding GO:0051098 3 0.017
cellular amino acid metabolic process GO:0006520 7 0.017
dorsal ventral pattern formation GO:0009953 125 0.016
double strand break repair via homologous recombination GO:0000724 1 0.016
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.016
neuron projection development GO:0031175 180 0.016
translational initiation GO:0006413 3 0.016
transcription dna templated GO:0006351 181 0.016
cellular response to extracellular stimulus GO:0031668 2 0.016
muscle cell development GO:0055001 115 0.016
positive regulation of secretion by cell GO:1903532 1 0.016
regulation of cytokine production GO:0001817 3 0.016
nuclear transport GO:0051169 4 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.016
axonogenesis GO:0007409 152 0.016
chemotaxis GO:0006935 104 0.016
cellular protein modification process GO:0006464 100 0.016
negative regulation of protein kinase activity GO:0006469 4 0.016
regulation of gtpase activity GO:0043087 2 0.015
golgi organization GO:0007030 1 0.015
adult behavior GO:0030534 2 0.015
positive regulation of secretion GO:0051047 1 0.015
regulation of cytoplasmic transport GO:1903649 4 0.015
meiotic cell cycle process GO:1903046 3 0.015
negative regulation of kinase activity GO:0033673 4 0.015
regulation of phosphorus metabolic process GO:0051174 43 0.015
regulation of nucleic acid templated transcription GO:1903506 213 0.015
mitotic cell cycle GO:0000278 64 0.015
death GO:0016265 121 0.015
negative regulation of cellular metabolic process GO:0031324 77 0.015
central nervous system development GO:0007417 387 0.015
developmental maturation GO:0021700 34 0.015
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.015
regulation of protein targeting GO:1903533 2 0.015
taxis GO:0042330 109 0.015
embryonic pattern specification GO:0009880 44 0.015
striated muscle cell development GO:0055002 108 0.015
response to abiotic stimulus GO:0009628 122 0.014
establishment of localization in cell GO:0051649 77 0.014
alcohol biosynthetic process GO:0046165 2 0.014
cell motility GO:0048870 244 0.014
ear development GO:0043583 127 0.014
negative regulation of molecular function GO:0044092 23 0.014
positive regulation of embryonic development GO:0040019 3 0.014
neurotransmitter transport GO:0006836 2 0.014
neuroblast proliferation GO:0007405 2 0.014
macromolecular complex subunit organization GO:0043933 74 0.014
protein polymerization GO:0051258 4 0.014
positive regulation of cellular process GO:0048522 201 0.014
positive regulation of cellular catabolic process GO:0031331 3 0.014
regulation of metal ion transport GO:0010959 4 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
protein targeting to membrane GO:0006612 1 0.014
regulation of protein ubiquitination GO:0031396 3 0.014
organic cyclic compound biosynthetic process GO:1901362 223 0.014
positive regulation of nucleotide catabolic process GO:0030813 1 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.014
regulation of protein transport GO:0051223 3 0.014
regulation of erk1 and erk2 cascade GO:0070372 4 0.014
single organism biosynthetic process GO:0044711 71 0.013
tube formation GO:0035148 25 0.013
ubiquitin dependent protein catabolic process GO:0006511 3 0.013
i kappab kinase nf kappab signaling GO:0007249 4 0.013
inner ear development GO:0048839 126 0.013
macromolecule localization GO:0033036 54 0.013
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.013
heterocycle biosynthetic process GO:0018130 215 0.013
homeostatic process GO:0042592 142 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
regulation of cellular biosynthetic process GO:0031326 245 0.013
nuclear import GO:0051170 3 0.013
extrinsic apoptotic signaling pathway GO:0097191 3 0.013
photoreceptor cell morphogenesis GO:0008594 1 0.013
cellular response to organic cyclic compound GO:0071407 38 0.013
embryonic heart tube morphogenesis GO:0003143 108 0.013
golgi vesicle transport GO:0048193 3 0.013
cell morphogenesis involved in differentiation GO:0000904 195 0.013
cellular protein catabolic process GO:0044257 4 0.013
positive regulation of dna metabolic process GO:0051054 1 0.013
muscle structure development GO:0061061 196 0.013
positive regulation of catabolic process GO:0009896 4 0.013
response to unfolded protein GO:0006986 2 0.013
negative regulation of metabolic process GO:0009892 86 0.013
regulation of jak stat cascade GO:0046425 3 0.013
regulation of cellular component organization GO:0051128 86 0.013
positive regulation of nucleoside metabolic process GO:0045979 1 0.013
neuron projection morphogenesis GO:0048812 161 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
aromatic compound biosynthetic process GO:0019438 217 0.013
regulation of protein import into nucleus GO:0042306 2 0.013
cytokinesis GO:0000910 3 0.013
regulation of cellular ketone metabolic process GO:0010565 7 0.013
sensory perception of pain GO:0019233 1 0.013
negative regulation of cell communication GO:0010648 96 0.013
protein localization to nucleus GO:0034504 3 0.012
cell aging GO:0007569 2 0.012
cellular response to starvation GO:0009267 1 0.012
negative regulation of protein phosphorylation GO:0001933 4 0.012
oocyte anterior posterior axis specification GO:0007314 4 0.012
regulation of cell shape GO:0008360 1 0.012
centrosome organization GO:0051297 1 0.012
cellular component disassembly GO:0022411 1 0.012
outflow tract morphogenesis GO:0003151 1 0.012
cellular carbohydrate metabolic process GO:0044262 4 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
regulation of reproductive process GO:2000241 4 0.012
reproduction GO:0000003 40 0.012
Worm
regulation of hydrolase activity GO:0051336 28 0.012
nephron epithelium morphogenesis GO:0072088 1 0.012
regulation of protein binding GO:0043393 3 0.012
mesoderm development GO:0007498 88 0.012
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.012
regulation of cell cycle GO:0051726 52 0.012
multicellular organismal response to stress GO:0033555 2 0.012
proteasomal protein catabolic process GO:0010498 2 0.012
hematopoietic or lymphoid organ development GO:0048534 191 0.012
protein n linked glycosylation GO:0006487 1 0.012
cellular response to endogenous stimulus GO:0071495 68 0.012
muscle cell migration GO:0014812 4 0.012
female sex differentiation GO:0046660 4 0.012
negative regulation of macromolecule metabolic process GO:0010605 76 0.012
response to carbohydrate GO:0009743 3 0.012
ameboidal type cell migration GO:0001667 143 0.012
ribosomal small subunit biogenesis GO:0042274 2 0.012
regulation of meiotic cell cycle GO:0051445 1 0.011
organic substance transport GO:0071702 58 0.011
nucleobase containing compound transport GO:0015931 2 0.011
regulation of localization GO:0032879 104 0.011
cellular response to oxygen levels GO:0071453 1 0.011
protein import GO:0017038 3 0.011
modification dependent protein catabolic process GO:0019941 3 0.011
positive regulation of response to stimulus GO:0048584 80 0.011
positive regulation of metabolic process GO:0009893 108 0.011
single organism nuclear import GO:1902593 3 0.011
carbohydrate biosynthetic process GO:0016051 1 0.011
sensory organ morphogenesis GO:0090596 200 0.011
meiotic chromosome segregation GO:0045132 3 0.011
positive regulation of map kinase activity GO:0043406 3 0.011
cellular response to stress GO:0033554 62 0.011
axon development GO:0061564 166 0.011
muscle cell differentiation GO:0042692 139 0.011
nucleobase containing compound biosynthetic process GO:0034654 205 0.011
response to corticosteroid GO:0031960 1 0.011
carbohydrate homeostasis GO:0033500 1 0.011
cellular response to unfolded protein GO:0034620 2 0.011
regulation of phosphate metabolic process GO:0019220 43 0.011
response to endogenous stimulus GO:0009719 83 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.011
regulation of transcription dna templated GO:0006355 213 0.011
mitochondrion organization GO:0007005 4 0.011
renal tubule morphogenesis GO:0061333 1 0.011
regulation of macromolecule biosynthetic process GO:0010556 225 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
cell matrix adhesion GO:0007160 4 0.011
intracellular signal transduction GO:0035556 85 0.011
organelle fusion GO:0048284 3 0.011
hormone transport GO:0009914 2 0.011
regulation of synapse assembly GO:0051963 3 0.011
double strand break repair GO:0006302 3 0.010
response to monosaccharide GO:0034284 3 0.010
response to nutrient GO:0007584 3 0.010
nephron tubule morphogenesis GO:0072078 1 0.010
heart looping GO:0001947 94 0.010
vasculature development GO:0001944 278 0.010
regulation of protein catabolic process GO:0042176 1 0.010
tyrosine phosphorylation of stat protein GO:0007260 1 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.010
negative regulation of cytoplasmic transport GO:1903650 2 0.010
negative regulation of intracellular transport GO:0032387 3 0.010
regulation of rna metabolic process GO:0051252 224 0.010
eye development GO:0001654 277 0.010
negative regulation of signaling GO:0023057 96 0.010
peptidyl serine phosphorylation GO:0018105 1 0.010
secondary metabolic process GO:0019748 3 0.010
striated muscle cell differentiation GO:0051146 129 0.010
exocytosis GO:0006887 1 0.010
multicellular organismal reproductive process GO:0048609 35 0.010
centrosome cycle GO:0007098 1 0.010
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.010
camera type eye development GO:0043010 222 0.010
single organism membrane fusion GO:0044801 2 0.010
positive regulation of cell activation GO:0050867 1 0.010
regulation of protein localization to nucleus GO:1900180 2 0.010

spcs2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.037
nervous system disease DOID:863 0 0.021
disease of metabolism DOID:0014667 0 0.018
eye and adnexa disease DOID:1492 0 0.014
eye disease DOID:5614 0 0.014
sensory system disease DOID:0050155 0 0.014
inherited metabolic disorder DOID:655 0 0.013