Danio rerio

80 known processes

spns2

spinster homolog 2 (Drosophila)

(Aliases: fi20h04,MGC175116,toh,wu:fi20h04,si:dkey-7b17.4)

spns2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
immune system development GO:0002520 191 0.998
Mouse
hematopoietic or lymphoid organ development GO:0048534 191 0.982
Mouse
localization of cell GO:0051674 244 0.982
tube morphogenesis GO:0035239 349 0.957
heart jogging GO:0003146 40 0.944
immune system process GO:0002376 241 0.937
Mouse
cell migration GO:0016477 237 0.928
digestive tract morphogenesis GO:0048546 231 0.909
cellular component movement GO:0006928 335 0.887
convergent extension involved in gastrulation GO:0060027 71 0.876
cell motility GO:0048870 244 0.871
heart development GO:0007507 313 0.868
ameboidal type cell migration GO:0001667 143 0.866
endodermal cell fate determination GO:0007493 2 0.852
locomotion GO:0040011 313 0.849
digestive tract development GO:0048565 265 0.847
nucleic acid templated transcription GO:0097659 181 0.842
digestive system development GO:0055123 289 0.831
fin development GO:0033333 77 0.830
cell migration involved in gastrulation GO:0042074 79 0.827
heart morphogenesis GO:0003007 156 0.818
embryonic organ development GO:0048568 381 0.815
regulation of primary metabolic process GO:0080090 311 0.797
regulation of response to stimulus GO:0048583 269 0.786
Mouse Fly
nitrogen compound metabolic process GO:0006807 319 0.776
Mouse
regulation of macromolecule biosynthetic process GO:0010556 225 0.776
regulation of nucleic acid templated transcription GO:1903506 213 0.736
embryonic organ morphogenesis GO:0048562 274 0.733
blood vessel morphogenesis GO:0048514 216 0.732
aromatic compound biosynthetic process GO:0019438 217 0.724
regionalization GO:0003002 274 0.714
convergent extension GO:0060026 118 0.688
cell surface receptor signaling pathway GO:0007166 325 0.669
rna biosynthetic process GO:0032774 181 0.666
head development GO:0060322 303 0.614
cell morphogenesis GO:0000902 289 0.608
myeloid cell differentiation GO:0030099 86 0.602
gastrulation GO:0007369 208 0.598
mesenchyme development GO:0060485 127 0.587
regulation of biological quality GO:0065008 263 0.581
Mouse Fly
positive regulation of transcription dna templated GO:0045893 57 0.576
erythrocyte homeostasis GO:0034101 55 0.573
cellular nitrogen compound biosynthetic process GO:0044271 218 0.570
regulation of cell communication GO:0010646 232 0.567
Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.550
negative regulation of cellular process GO:0048523 283 0.545
Fly
stem cell differentiation GO:0048863 117 0.538
chordate embryonic development GO:0043009 271 0.537
cellular macromolecule metabolic process GO:0044260 391 0.535
skeletal system development GO:0001501 181 0.526
eye development GO:0001654 277 0.526
cellular macromolecule biosynthetic process GO:0034645 224 0.524
mesenchymal cell differentiation GO:0048762 87 0.521
regulation of rna metabolic process GO:0051252 224 0.516
regulation of bmp signaling pathway GO:0030510 39 0.513
embryonic skeletal system morphogenesis GO:0048704 93 0.512
notochord morphogenesis GO:0048570 17 0.506
cartilage development GO:0051216 96 0.492
enzyme linked receptor protein signaling pathway GO:0007167 106 0.490
Fly
cardiac chamber development GO:0003205 19 0.490
blood circulation GO:0008015 87 0.485
heterocycle biosynthetic process GO:0018130 215 0.481
fin regeneration GO:0031101 51 0.478
regulation of developmental process GO:0050793 247 0.477
response to wounding GO:0009611 116 0.469
cellular nitrogen compound metabolic process GO:0034641 290 0.468
response to fluid shear stress GO:0034405 2 0.464
myeloid cell homeostasis GO:0002262 56 0.456
cellular component assembly GO:0022607 170 0.450
Fly
transcription dna templated GO:0006351 181 0.450
regulation of calcium dependent cell cell adhesion GO:0046586 1 0.450
regulation of epithelial cell proliferation GO:0050678 3 0.443
neural crest cell differentiation GO:0014033 72 0.434
regulation of cell migration GO:0030334 40 0.429
regulation of macromolecule metabolic process GO:0060255 317 0.425
cellular aromatic compound metabolic process GO:0006725 295 0.416
blood vessel development GO:0001568 246 0.411
determination of ventral identity GO:0048264 21 0.409
cellular component morphogenesis GO:0032989 336 0.403
regulation of synapse organization GO:0050807 3 0.396
Fly
larval development GO:0002164 2 0.390
Worm
proepicardium development GO:0003342 4 0.387
homeostatic process GO:0042592 142 0.378
Mouse
appendage development GO:0048736 80 0.374
regulation of gene expression GO:0010468 265 0.371
embryonic heart tube left right pattern formation GO:0060971 5 0.370
rna metabolic process GO:0016070 219 0.365
embryonic heart tube development GO:0035050 133 0.364
cellular response to growth factor stimulus GO:0071363 39 0.354
bmp signaling pathway GO:0030509 52 0.351
behavior GO:0007610 74 0.347
Fly
positive regulation of epithelial cell proliferation GO:0050679 1 0.344
embryonic heart tube morphogenesis GO:0003143 108 0.343
regulation of apoptotic process GO:0042981 98 0.342
Fly
organic cyclic compound biosynthetic process GO:1901362 223 0.341
macromolecule biosynthetic process GO:0009059 227 0.338
response to growth factor GO:0070848 39 0.337
regulation of signal transduction GO:0009966 225 0.326
Fly
hemopoiesis GO:0030097 183 0.323
phosphorylation GO:0016310 69 0.322
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.314
erythrocyte differentiation GO:0030218 54 0.305
positive regulation of nucleic acid templated transcription GO:1903508 57 0.304
regulation of cellular biosynthetic process GO:0031326 245 0.300
embryonic cranial skeleton morphogenesis GO:0048701 90 0.298
regulation of biosynthetic process GO:0009889 250 0.297
regulation of transcription dna templated GO:0006355 213 0.292
dorsal convergence GO:0060030 14 0.285
neuron development GO:0048666 262 0.282
regulation of multicellular organismal development GO:2000026 223 0.280
diencephalon development GO:0021536 58 0.280
artery development GO:0060840 22 0.270
connective tissue development GO:0061448 99 0.267
anterior posterior pattern specification GO:0009952 152 0.263
vasculature development GO:0001944 278 0.260
regulation of cellular metabolic process GO:0031323 320 0.260
stem cell maintenance GO:0019827 4 0.257
mesenchymal cell development GO:0014031 78 0.245
embryonic hemopoiesis GO:0035162 53 0.244
regulation of signaling GO:0023051 235 0.244
Fly
nucleic acid metabolic process GO:0090304 244 0.243
pectoral fin development GO:0033339 50 0.241
hematopoietic stem cell differentiation GO:0060218 20 0.240
biosynthetic process GO:0009058 294 0.234
nucleobase containing compound biosynthetic process GO:0034654 205 0.234
cellular biosynthetic process GO:0044249 286 0.232
central nervous system formation GO:0021556 1 0.231
dorsal ventral pattern formation GO:0009953 125 0.227
embryonic viscerocranium morphogenesis GO:0048703 52 0.223
morphogenesis of an epithelium GO:0002009 333 0.221
neural crest cell development GO:0014032 62 0.219
regulation of cell differentiation GO:0045595 142 0.219
Fly
regulation of reactive oxygen species metabolic process GO:2000377 2 0.214
mesodermal cell fate commitment GO:0001710 14 0.211
stem cell development GO:0048864 82 0.209
determination of dorsal ventral asymmetry GO:0048262 34 0.208
negative regulation of response to stimulus GO:0048585 104 0.205
Fly
response to organic substance GO:0010033 153 0.204
odontogenesis of dentin containing tooth GO:0042475 1 0.204
gland development GO:0048732 143 0.204
regulation of cellular response to growth factor stimulus GO:0090287 35 0.201
positive regulation of rna metabolic process GO:0051254 59 0.199
regulation of cell proliferation GO:0042127 37 0.198
wound healing GO:0042060 90 0.197
regulation of dna templated transcription in response to stress GO:0043620 0 0.197
protein metabolic process GO:0019538 183 0.191
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.191
tissue regeneration GO:0042246 74 0.190
determination of heart left right asymmetry GO:0061371 117 0.189
organic cyclic compound metabolic process GO:1901360 301 0.188
system process GO:0003008 185 0.187
negative regulation of wnt signaling pathway GO:0030178 30 0.186
dna templated transcription elongation GO:0006354 3 0.185
lymphocyte differentiation GO:0030098 9 0.185
determination of left right asymmetry in diencephalon GO:0035462 4 0.185
neural crest cell migration GO:0001755 42 0.183
retina development in camera type eye GO:0060041 146 0.181
embryo development ending in birth or egg hatching GO:0009792 271 0.180
organic substance biosynthetic process GO:1901576 289 0.177
synaptic growth at neuromuscular junction GO:0051124 2 0.177
Fly
mesoderm morphogenesis GO:0048332 51 0.177
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.174
heterocycle metabolic process GO:0046483 290 0.170
macromolecule modification GO:0043412 111 0.169
negative regulation of calcium dependent cell cell adhesion GO:0046588 1 0.167
cell morphogenesis involved in differentiation GO:0000904 195 0.167
meiotic nuclear division GO:0007126 4 0.165
regulation of tube size GO:0035150 2 0.163
heart rudiment formation GO:0003315 5 0.163
endodermal cell differentiation GO:0035987 19 0.161
central nervous system development GO:0007417 387 0.160
Fly
epithelial tube morphogenesis GO:0060562 148 0.159
determination of left right symmetry GO:0007368 179 0.156
determination of left right asymmetry in nervous system GO:0035545 4 0.153
gene expression GO:0010467 252 0.152
regulation of immune system process GO:0002682 34 0.151
Mouse
heart valve formation GO:0003188 4 0.148
cell projection organization GO:0030030 284 0.141
embryonic skeletal system development GO:0048706 97 0.141
vascular process in circulatory system GO:0003018 6 0.135
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.135
regulation of cell motility GO:2000145 46 0.133
tube closure GO:0060606 1 0.132
regulation of multicellular organismal process GO:0051239 277 0.132
regulation of cell projection assembly GO:0060491 4 0.130
neural tube development GO:0021915 62 0.129
positive regulation of signal transduction GO:0009967 56 0.128
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.126
mesoderm formation GO:0001707 43 0.126
phagocytosis engulfment GO:0006911 1 0.126
positive regulation of multicellular organismal process GO:0051240 52 0.125
regulation of nitrogen compound metabolic process GO:0051171 251 0.124
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.124
Fly
fin morphogenesis GO:0033334 53 0.124
wnt signaling pathway GO:0016055 80 0.123
inner ear development GO:0048839 126 0.122
formation of primary germ layer GO:0001704 62 0.120
regulation of protein metabolic process GO:0051246 56 0.120
positive regulation of cellular metabolic process GO:0031325 94 0.119
regulation of rna biosynthetic process GO:2001141 213 0.119
maintenance of location GO:0051235 4 0.117
vasculogenesis GO:0001570 41 0.117
regulation of synapse assembly GO:0051963 3 0.116
Fly
septum transversum development GO:0003343 4 0.116
pathway restricted smad protein phosphorylation GO:0060389 1 0.115
regulation of anatomical structure morphogenesis GO:0022603 130 0.114
positive regulation of striated muscle tissue development GO:0045844 1 0.114
leukocyte differentiation GO:0002521 25 0.113
cellular response to chemical stimulus GO:0070887 157 0.112
regulation of localization GO:0032879 104 0.111
response to external stimulus GO:0009605 264 0.111
Fly
axial mesoderm formation GO:0048320 4 0.110
developmental growth GO:0048589 166 0.110
Fly
phosphate containing compound metabolic process GO:0006796 108 0.109
heart looping GO:0001947 94 0.108
ovulation cycle process GO:0022602 2 0.106
regulation of neurogenesis GO:0050767 87 0.105
endoderm development GO:0007492 49 0.104
positive regulation of metabolic process GO:0009893 108 0.103
response to stress GO:0006950 263 0.100
Fly
hematopoietic progenitor cell differentiation GO:0002244 23 0.099
heart process GO:0003015 71 0.099
germ line stem cell division GO:0042078 1 0.099
circulatory system process GO:0003013 87 0.097
regeneration GO:0031099 91 0.097
regulation of protein catabolic process GO:0042176 1 0.096
endodermal cell fate commitment GO:0001711 18 0.096
regulation of binding GO:0051098 3 0.094
regulation of metabolic process GO:0019222 359 0.094
regulation of establishment of protein localization GO:0070201 4 0.094
specification of organ position GO:0010159 3 0.094
transcription from rna polymerase ii promoter GO:0006366 80 0.094
neural plate regionalization GO:0060897 10 0.092
liver development GO:0001889 96 0.092
regulation of biomineral tissue development GO:0070167 2 0.091
negative regulation of mapk cascade GO:0043409 4 0.091
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.089
negative regulation of mesodermal cell fate specification GO:0042662 3 0.089
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.089
regulation of cytoplasmic transport GO:1903649 4 0.088
positive regulation of muscle organ development GO:0048636 1 0.088
regulation of cellular component movement GO:0051270 55 0.088
response to glucocorticoid GO:0051384 1 0.087
olfactory bulb development GO:0021772 4 0.087
female sex differentiation GO:0046660 4 0.087
multicellular organism growth GO:0035264 4 0.086
organonitrogen compound metabolic process GO:1901564 74 0.086
Mouse
regulation of cytokine production GO:0001817 3 0.084
regulation of dna templated transcription elongation GO:0032784 3 0.084
negative regulation of cell adhesion GO:0007162 6 0.084
regulation of molecular function GO:0065009 70 0.083
ovulation cycle GO:0042698 2 0.082
endoderm formation GO:0001706 29 0.082
positive regulation of epithelial cell migration GO:0010634 2 0.081
peptidyl threonine phosphorylation GO:0018107 1 0.079
nucleobase containing compound metabolic process GO:0006139 274 0.079
positive regulation of response to stimulus GO:0048584 80 0.078
female gonad development GO:0008585 4 0.078
mesoderm development GO:0007498 88 0.077
signal transduction GO:0007165 455 0.077
regulation of wnt signaling pathway GO:0030111 53 0.077
cellular component biogenesis GO:0044085 178 0.077
Fly
protein polymerization GO:0051258 4 0.076
positive regulation of cell activation GO:0050867 1 0.076
hepaticobiliary system development GO:0061008 98 0.074
homeostasis of number of cells GO:0048872 62 0.074
Mouse
meiotic chromosome segregation GO:0045132 3 0.074
single organism reproductive process GO:0044702 40 0.073
Worm Fly
cell fate commitment GO:0045165 99 0.073
regulation of bone mineralization GO:0030500 2 0.073
regulation of phosphate metabolic process GO:0019220 43 0.073
chemotaxis GO:0006935 104 0.073
regulation of nucleocytoplasmic transport GO:0046822 2 0.073
axonal defasciculation GO:0007414 2 0.072
primary neural tube formation GO:0014020 1 0.072
epithelial to mesenchymal transition GO:0001837 21 0.072
outflow tract morphogenesis GO:0003151 1 0.071
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.071
chemical homeostasis GO:0048878 49 0.069
positive regulation of catabolic process GO:0009896 4 0.068
single organism metabolic process GO:0044710 217 0.068
Mouse
steroid hormone mediated signaling pathway GO:0043401 9 0.068
regulation of blood pressure GO:0008217 1 0.068
negative regulation of signaling GO:0023057 96 0.068
Fly
canonical wnt signaling pathway GO:0060070 48 0.067
taxis GO:0042330 109 0.067
odontogenesis GO:0042476 9 0.067
eye morphogenesis GO:0048592 144 0.067
sensory organ development GO:0007423 393 0.066
cellular response to organic substance GO:0071310 105 0.066
appendage morphogenesis GO:0035107 56 0.065
regulation of locomotion GO:0040012 55 0.065
non canonical wnt signaling pathway GO:0035567 13 0.065
positive regulation of cellular component biogenesis GO:0044089 3 0.065
positive regulation of biosynthetic process GO:0009891 68 0.064
regulation of blood vessel size GO:0050880 2 0.064
cellular component disassembly GO:0022411 1 0.064
brain development GO:0007420 293 0.063
positive regulation of cellular process GO:0048522 201 0.063
regulation of system process GO:0044057 40 0.062
membrane invagination GO:0010324 1 0.061
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.060
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.060
specification of symmetry GO:0009799 204 0.060
immune response GO:0006955 28 0.059
Mouse
macromolecular complex subunit organization GO:0043933 74 0.059
pericardium development GO:0060039 1 0.059
positive regulation of dna templated transcription elongation GO:0032786 1 0.059
positive regulation of biological process GO:0048518 253 0.059
positive regulation of locomotion GO:0040017 14 0.058
myeloid leukocyte differentiation GO:0002573 15 0.058
reactive oxygen species metabolic process GO:0072593 6 0.058
camera type eye development GO:0043010 222 0.058
negative regulation of gastrulation GO:2000542 11 0.057
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.057
lateral mesoderm development GO:0048368 23 0.056
cellular protein modification process GO:0006464 100 0.056
actin filament based process GO:0030029 64 0.056
endodermal digestive tract morphogenesis GO:0061031 2 0.056
cellular response to fluid shear stress GO:0071498 1 0.056
response to other organism GO:0051707 97 0.056
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.055
protein modification process GO:0036211 100 0.055
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.054
Fly
response to biotic stimulus GO:0009607 97 0.054
regulation of protein complex assembly GO:0043254 3 0.054
protein complex assembly GO:0006461 30 0.054
oligodendrocyte differentiation GO:0048709 23 0.054
growth GO:0040007 174 0.053
Fly
regulation of heart growth GO:0060420 2 0.053
single organism nuclear import GO:1902593 3 0.053
skeletal system morphogenesis GO:0048705 102 0.053
developmental programmed cell death GO:0010623 4 0.052
Fly
negative regulation of secretion GO:0051048 2 0.052
single organism organelle organization GO:1902589 199 0.052
negative regulation of biological process GO:0048519 304 0.051
Fly
organelle organization GO:0006996 227 0.051
Fly
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.051
regulation of oocyte development GO:0060281 3 0.051
muscle structure development GO:0061061 196 0.051
cardiac atrium development GO:0003230 4 0.051
somatic stem cell maintenance GO:0035019 1 0.051
phagocytosis GO:0006909 3 0.050
protein complex biogenesis GO:0070271 30 0.049
regulation of erythrocyte differentiation GO:0045646 2 0.049
regulation of embryonic development GO:0045995 47 0.049
generation of neurons GO:0048699 385 0.048
sensory organ morphogenesis GO:0090596 200 0.048
negative regulation of cell migration GO:0030336 17 0.048
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.048
gastrulation with mouth forming second GO:0001702 44 0.048
negative regulation of developmental process GO:0051093 65 0.048
positive regulation of endothelial cell migration GO:0010595 2 0.048
small gtpase mediated signal transduction GO:0007264 8 0.048
heart rudiment morphogenesis GO:0003314 6 0.047
macromolecular complex disassembly GO:0032984 1 0.047
renal system process involved in regulation of blood volume GO:0001977 1 0.047
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.047
leukocyte chemotaxis GO:0030595 12 0.047
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.046
regulation of rho protein signal transduction GO:0035023 2 0.046
regulation of cellular component organization GO:0051128 86 0.045
Fly
ovarian follicle development GO:0001541 2 0.045
positive regulation of cellular biosynthetic process GO:0031328 68 0.045
epithelial cell differentiation GO:0030855 116 0.045
regulation of cardiac muscle tissue development GO:0055024 1 0.045
reactive oxygen species biosynthetic process GO:1903409 1 0.045
development of primary female sexual characteristics GO:0046545 4 0.044
hatching GO:0035188 4 0.044
otic vesicle development GO:0071599 42 0.044
aorta development GO:0035904 4 0.044
hormone secretion GO:0046879 2 0.044
negative regulation of mitosis GO:0045839 3 0.043
somitogenesis GO:0001756 87 0.043
protein complex subunit organization GO:0071822 46 0.043
regulation of mesoderm development GO:2000380 11 0.042
single organism transport GO:0044765 206 0.042
Mouse Fly
regulation of cellular component size GO:0032535 30 0.041
positive regulation of rna biosynthetic process GO:1902680 57 0.041
positive regulation of developmental process GO:0051094 50 0.041
b cell activation GO:0042113 2 0.041
regulation of cardiac muscle cell differentiation GO:2000725 1 0.040
regulation of mesodermal cell fate specification GO:0042661 9 0.040
negative regulation of cytokine production GO:0001818 1 0.040
erythrocyte development GO:0048821 24 0.040
retina morphogenesis in camera type eye GO:0060042 79 0.040
phosphorus metabolic process GO:0006793 109 0.040
regulation of ion transmembrane transporter activity GO:0032412 2 0.040
neural retina development GO:0003407 49 0.040
macromolecule localization GO:0033036 54 0.039
Mouse
otic placode formation GO:0043049 23 0.039
macromolecular complex assembly GO:0065003 35 0.038
regulation of chemotaxis GO:0050920 18 0.038
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.038
protein complex disassembly GO:0043241 1 0.037
positive regulation of cell adhesion GO:0045785 1 0.037
negative regulation of protein phosphorylation GO:0001933 4 0.037
rna localization GO:0006403 4 0.037
neuron projection development GO:0031175 180 0.037
regulation of behavior GO:0050795 24 0.037
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.037
death GO:0016265 121 0.037
Fly
axon development GO:0061564 166 0.037
wnt signaling pathway involved in somitogenesis GO:0090244 2 0.036
ectodermal placode development GO:0071696 37 0.036
cellular response to hormone stimulus GO:0032870 39 0.036
protein import GO:0017038 3 0.036
segmentation GO:0035282 97 0.036
peptidyl threonine modification GO:0018210 1 0.036
spemann organizer formation GO:0060061 10 0.036
response to endogenous stimulus GO:0009719 83 0.036
cellular response to endogenous stimulus GO:0071495 68 0.035
single organism cell adhesion GO:0098602 29 0.035
axial mesoderm development GO:0048318 10 0.035
regulation of reproductive process GO:2000241 4 0.035
Fly
positive regulation of transport GO:0051050 2 0.034
negative regulation of epithelial cell proliferation GO:0050680 1 0.034
regulation of cytoskeleton organization GO:0051493 11 0.034
small molecule metabolic process GO:0044281 77 0.034
regulation of nervous system development GO:0051960 90 0.034
Fly
spinal cord development GO:0021510 46 0.034
bmp signaling pathway involved in heart development GO:0061312 15 0.034
regulation of cell projection organization GO:0031344 44 0.033
heart contraction GO:0060047 71 0.033
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.033
mesodermal cell differentiation GO:0048333 21 0.033
embryonic digestive tract morphogenesis GO:0048557 3 0.033
cranial nerve development GO:0021545 42 0.032
notochord development GO:0030903 54 0.032
regulation of systemic arterial blood pressure GO:0003073 1 0.032
gamete generation GO:0007276 33 0.032
Worm Fly
regulation of meiotic cell cycle GO:0051445 1 0.032
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.032
neuron projection morphogenesis GO:0048812 161 0.032
cellular response to estradiol stimulus GO:0071392 1 0.032
negative regulation of immune system process GO:0002683 7 0.031
medial fin development GO:0033338 16 0.031
skin development GO:0043588 54 0.031
positive regulation of phosphate metabolic process GO:0045937 21 0.031
negative regulation of metabolic process GO:0009892 86 0.031
determination of bilateral symmetry GO:0009855 204 0.031
nitric oxide biosynthetic process GO:0006809 2 0.031
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.031
establishment of localization GO:0051234 244 0.030
Mouse Fly
axial mesoderm morphogenesis GO:0048319 8 0.030
negative regulation of protein complex assembly GO:0031333 1 0.030
endocardial cushion morphogenesis GO:0003203 3 0.030
response to fibroblast growth factor GO:0071774 22 0.030
primitive erythrocyte differentiation GO:0060319 5 0.030
response to drug GO:0042493 3 0.030
response to chemical GO:0042221 320 0.030
organelle assembly GO:0070925 110 0.030
determination of left right asymmetry in lateral mesoderm GO:0003140 20 0.030
gtp catabolic process GO:0006184 2 0.030
regulation of organ morphogenesis GO:2000027 35 0.029
cell adhesion GO:0007155 40 0.029
negative regulation of map kinase activity GO:0043407 2 0.029
regulation of cartilage development GO:0061035 7 0.029
neural tube formation GO:0001841 16 0.029
embryonic neurocranium morphogenesis GO:0048702 15 0.029
regulation of cellular protein metabolic process GO:0032268 52 0.029
actin cytoskeleton organization GO:0030036 63 0.029
positive regulation of cell migration GO:0030335 11 0.029
paraxial mesoderm development GO:0048339 8 0.029
single organismal cell cell adhesion GO:0016337 29 0.029
regulation of phosphorus metabolic process GO:0051174 43 0.028
nuclear export GO:0051168 1 0.028
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.028
hormone mediated signaling pathway GO:0009755 9 0.028
defense response to fungus GO:0050832 2 0.028
protein homooligomerization GO:0051260 3 0.028
response to lipid GO:0033993 60 0.028
embryonic epithelial tube formation GO:0001838 17 0.027
somatic muscle development GO:0007525 4 0.027
cell proliferation GO:0008283 80 0.027
cartilage morphogenesis GO:0060536 13 0.027
antimicrobial humoral response GO:0019730 2 0.027
negative regulation of cellular component movement GO:0051271 18 0.027
otic vesicle formation GO:0030916 27 0.027
nuclear import GO:0051170 3 0.027
g1 s transition of mitotic cell cycle GO:0000082 1 0.027
skeletal muscle tissue development GO:0007519 67 0.027
cell cell signaling GO:0007267 52 0.027
Fly
locomotory behavior GO:0007626 34 0.026
positive regulation of skeletal muscle tissue development GO:0048643 1 0.026
myeloid cell development GO:0061515 32 0.026
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.026
olfactory lobe development GO:0021988 4 0.026
adult behavior GO:0030534 2 0.026
lipid storage GO:0019915 1 0.026
regulation of erk1 and erk2 cascade GO:0070372 4 0.026
cell type specific apoptotic process GO:0097285 22 0.026
Fly
regulation of cell killing GO:0031341 2 0.026

spns2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.354
cancer DOID:162 0 0.027
disease of cellular proliferation DOID:14566 0 0.027