Danio rerio

0 known processes

spon1b

spondin 1b

(Aliases: cb1051,F-spondin2)

spon1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chordate embryonic development GO:0043009 271 0.431
developmental growth GO:0048589 166 0.426
cognition GO:0050890 1 0.411
regulation of cell communication GO:0010646 232 0.384
axonogenesis GO:0007409 152 0.348
Worm
central nervous system development GO:0007417 387 0.343
cellular response to external stimulus GO:0071496 2 0.292
heart development GO:0007507 313 0.264
specification of symmetry GO:0009799 204 0.228
cell morphogenesis involved in differentiation GO:0000904 195 0.224
Worm
head development GO:0060322 303 0.220
programmed cell death GO:0012501 119 0.213
taxis GO:0042330 109 0.197
Worm
larval development GO:0002164 2 0.194
adult behavior GO:0030534 2 0.190
positive regulation of signal transduction GO:0009967 56 0.184
cardiac chamber development GO:0003205 19 0.178
positive regulation of translation GO:0045727 1 0.170
determination of bilateral symmetry GO:0009855 204 0.166
multicellular organismal response to stress GO:0033555 2 0.159
digestive tract development GO:0048565 265 0.155
cell surface receptor signaling pathway GO:0007166 325 0.149
determination of left right symmetry GO:0007368 179 0.143
organic cyclic compound metabolic process GO:1901360 301 0.140
lateral inhibition GO:0046331 1 0.137
axon guidance GO:0007411 86 0.133
Worm
regulation of response to stimulus GO:0048583 269 0.132
regionalization GO:0003002 274 0.127
heart morphogenesis GO:0003007 156 0.108
cellular response to extracellular stimulus GO:0031668 2 0.107
stem cell maintenance GO:0019827 4 0.104
branching morphogenesis of a nerve GO:0048755 4 0.103
cellular amine metabolic process GO:0044106 2 0.102
segmentation GO:0035282 97 0.102
regulation of blood pressure GO:0008217 1 0.102
single organism organelle organization GO:1902589 199 0.101
outflow tract morphogenesis GO:0003151 1 0.101
muscle organ development GO:0007517 101 0.101
Worm
olfactory lobe development GO:0021988 4 0.099
single organism metabolic process GO:0044710 217 0.099
olfactory bulb development GO:0021772 4 0.096
phagocytosis engulfment GO:0006911 1 0.095
response to external stimulus GO:0009605 264 0.095
Worm
forebrain development GO:0030900 96 0.094
embryonic organ development GO:0048568 381 0.093
gastrulation GO:0007369 208 0.093
cell part morphogenesis GO:0032990 246 0.092
Worm
aging GO:0007568 2 0.090
cellular response to starvation GO:0009267 1 0.089
regulation of cellular amine metabolic process GO:0033238 0 0.087
organonitrogen compound metabolic process GO:1901564 74 0.086
signal transduction GO:0007165 455 0.084
apoptotic process GO:0006915 116 0.081
compound eye development GO:0048749 2 0.080
morphogenesis of an epithelium GO:0002009 333 0.078
neuron projection development GO:0031175 180 0.076
Worm
erk1 and erk2 cascade GO:0070371 4 0.076
sprouting angiogenesis GO:0002040 53 0.076
regulation of developmental process GO:0050793 247 0.074
cell death GO:0008219 121 0.074
cellular amino acid metabolic process GO:0006520 7 0.071
cellular ketone metabolic process GO:0042180 11 0.071
cardiac chamber formation GO:0003207 4 0.071
epithelial tube morphogenesis GO:0060562 148 0.070
regulation of synapse organization GO:0050807 3 0.070
positive regulation of stem cell proliferation GO:2000648 1 0.070
death GO:0016265 121 0.067
multi organism process GO:0051704 134 0.067
neural tube development GO:0021915 62 0.067
response to drug GO:0042493 3 0.067
developmental growth involved in morphogenesis GO:0060560 86 0.067
regulation of multicellular organism growth GO:0040014 4 0.066
germ line stem cell maintenance GO:0030718 2 0.066
multicellular organism growth GO:0035264 4 0.065
brain development GO:0007420 293 0.065
small molecule metabolic process GO:0044281 77 0.065
negative regulation of gastrulation GO:2000542 11 0.065
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.064
photoreceptor cell fate commitment GO:0046552 1 0.062
tube morphogenesis GO:0035239 349 0.062
innervation GO:0060384 3 0.062
neuron projection morphogenesis GO:0048812 161 0.062
Worm
neuron development GO:0048666 262 0.062
Worm
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.060
cell adhesion GO:0007155 40 0.060
Worm
cell projection morphogenesis GO:0048858 244 0.059
Worm
multicellular organismal metabolic process GO:0044236 2 0.059
positive regulation of response to external stimulus GO:0032103 9 0.059
response to chemical GO:0042221 320 0.059
Worm
organelle organization GO:0006996 227 0.058
renal tubule morphogenesis GO:0061333 1 0.057
positive regulation of biological process GO:0048518 253 0.056
muscle structure development GO:0061061 196 0.055
Worm
eye development GO:0001654 277 0.055
cerebellar granular layer development GO:0021681 3 0.054
positive regulation of response to stimulus GO:0048584 80 0.053
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.051
growth GO:0040007 174 0.050
regulation of programmed cell death GO:0043067 101 0.050
cellular amino acid biosynthetic process GO:0008652 2 0.050
embryo development ending in birth or egg hatching GO:0009792 271 0.049
positive regulation of cell communication GO:0010647 56 0.049
regulation of cell morphogenesis GO:0022604 42 0.048
cellular response to nutrient levels GO:0031669 2 0.048
regulation of cellular ketone metabolic process GO:0010565 7 0.047
extracellular matrix organization GO:0030198 27 0.047
axon development GO:0061564 166 0.046
Worm
peptidyl serine phosphorylation GO:0018105 1 0.046
digestive tract morphogenesis GO:0048546 231 0.046
regulation of signaling GO:0023051 235 0.045
glucocorticoid metabolic process GO:0008211 2 0.045
mesenchymal cell proliferation GO:0010463 1 0.044
cell projection organization GO:0030030 284 0.044
Worm
meiotic nuclear division GO:0007126 4 0.044
heart looping GO:0001947 94 0.044
amine metabolic process GO:0009308 2 0.043
positive regulation of cytokine production GO:0001819 2 0.042
cardiac ventricle morphogenesis GO:0003208 7 0.042
neuron differentiation GO:0030182 353 0.042
Worm
protein metabolic process GO:0019538 183 0.042
carbohydrate homeostasis GO:0033500 1 0.042
regulation of cell death GO:0010941 103 0.042
sensory organ development GO:0007423 393 0.042
regulation of protein ubiquitination GO:0031396 3 0.041
determination of heart left right asymmetry GO:0061371 117 0.041
response to organic substance GO:0010033 153 0.041
response to glucose GO:0009749 3 0.040
positive regulation of cell death GO:0010942 29 0.040
stem cell differentiation GO:0048863 117 0.039
eye morphogenesis GO:0048592 144 0.039
digestive system development GO:0055123 289 0.038
response to glucocorticoid GO:0051384 1 0.038
regulation of localization GO:0032879 104 0.038
negative regulation of cell death GO:0060548 60 0.038
embryonic skeletal joint morphogenesis GO:0060272 3 0.037
membrane invagination GO:0010324 1 0.037
cell proliferation GO:0008283 80 0.037
glucose homeostasis GO:0042593 1 0.037
syncytium formation GO:0006949 12 0.036
somitogenesis GO:0001756 87 0.036
cartilage development GO:0051216 96 0.034
negative regulation of gliogenesis GO:0014014 1 0.034
regulation of developmental growth GO:0048638 38 0.034
embryonic heart tube morphogenesis GO:0003143 108 0.034
transport GO:0006810 220 0.034
phagocytosis GO:0006909 3 0.034
smoothened signaling pathway GO:0007224 30 0.033
positive regulation of striated muscle tissue development GO:0045844 1 0.033
endodermal cell fate determination GO:0007493 2 0.033
cardiac chamber morphogenesis GO:0003206 12 0.032
cell growth GO:0016049 57 0.032
response to hexose GO:0009746 3 0.032
cell morphogenesis GO:0000902 289 0.031
Worm
single organism localization GO:1902578 225 0.031
regulation of cell activation GO:0050865 1 0.031
lipid metabolic process GO:0006629 52 0.031
positive regulation of muscle organ development GO:0048636 1 0.031
nitrogen compound metabolic process GO:0006807 319 0.030
negative regulation of cell communication GO:0010648 96 0.030
skeletal system development GO:0001501 181 0.030
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.029
Worm
cell migration GO:0016477 237 0.029
lens fiber cell development GO:0070307 3 0.029
negative chemotaxis GO:0050919 1 0.029
cellular protein modification process GO:0006464 100 0.029
positive regulation of muscle tissue development GO:1901863 1 0.029
positive regulation of cell activation GO:0050867 1 0.029
collagen metabolic process GO:0032963 2 0.028
regulation of cell development GO:0060284 100 0.027
regulation of cellular protein metabolic process GO:0032268 52 0.027
regulation of response to nutrient levels GO:0032107 1 0.027
regulation of nervous system development GO:0051960 90 0.027
cytoskeleton organization GO:0007010 96 0.027
response to corticosteroid GO:0031960 1 0.027
positive regulation of cellular process GO:0048522 201 0.026
regulation of synapse assembly GO:0051963 3 0.026
extrinsic apoptotic signaling pathway GO:0097191 3 0.026
regulation of phosphorus metabolic process GO:0051174 43 0.026
axonogenesis involved in innervation GO:0060385 1 0.025
neuron death GO:0070997 21 0.025
embryonic heart tube development GO:0035050 133 0.025
regulation of organ growth GO:0046620 3 0.025
glutamate receptor signaling pathway GO:0007215 1 0.025
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.025
cellular component morphogenesis GO:0032989 336 0.025
Worm
positive regulation of cellular protein metabolic process GO:0032270 22 0.024
regulation of intracellular signal transduction GO:1902531 57 0.024
negative regulation of mesodermal cell fate specification GO:0042662 3 0.024
synaptic growth at neuromuscular junction GO:0051124 2 0.024
positive regulation of cellular component biogenesis GO:0044089 3 0.023
neuron projection guidance GO:0097485 86 0.023
Worm
cellular response to chemical stimulus GO:0070887 157 0.023
system process GO:0003008 185 0.023
response to inorganic substance GO:0010035 38 0.023
multi organism reproductive process GO:0044703 36 0.022
positive regulation of cell cycle GO:0045787 3 0.022
positive regulation of cellular amine metabolic process GO:0033240 0 0.022
response to endogenous stimulus GO:0009719 83 0.022
anterior posterior pattern specification GO:0009952 152 0.022
response to nutrient GO:0007584 3 0.022
regulation of multicellular organismal process GO:0051239 277 0.022
negative regulation of embryonic development GO:0045992 11 0.021
tissue remodeling GO:0048771 4 0.021
cellular macromolecule metabolic process GO:0044260 391 0.021
syncytium formation by plasma membrane fusion GO:0000768 12 0.021
limb bud formation GO:0060174 2 0.021
cell matrix adhesion GO:0007160 4 0.020
response to monosaccharide GO:0034284 3 0.020
regulation of apoptotic process GO:0042981 98 0.020
organic acid metabolic process GO:0006082 31 0.019
establishment of localization GO:0051234 244 0.019
positive regulation of catalytic activity GO:0043085 25 0.019
carboxylic acid metabolic process GO:0019752 22 0.019
embryonic organ morphogenesis GO:0048562 274 0.019
localization of cell GO:0051674 244 0.019
cell cycle process GO:0022402 53 0.019
cellular protein metabolic process GO:0044267 129 0.019
regulation of transcription involved in cell fate commitment GO:0060850 1 0.019
regulation of mesenchymal cell proliferation GO:0010464 1 0.019
negative regulation of endodermal cell differentiation GO:1903225 8 0.019
axon extension GO:0048675 45 0.019
positive regulation of multicellular organismal process GO:0051240 52 0.019
cell cycle GO:0007049 93 0.019
cell cycle g1 s phase transition GO:0044843 1 0.019
negative regulation of programmed cell death GO:0043069 58 0.019
regulation of cytokine production GO:0001817 3 0.019
regulation of molecular function GO:0065009 70 0.019
notochord development GO:0030903 54 0.019
heart valve morphogenesis GO:0003179 8 0.018
cell migration involved in gastrulation GO:0042074 79 0.018
cell motility GO:0048870 244 0.018
positive regulation of catabolic process GO:0009896 4 0.018
phosphate containing compound metabolic process GO:0006796 108 0.018
cellular component assembly GO:0022607 170 0.018
hormone secretion GO:0046879 2 0.018
response to carbohydrate GO:0009743 3 0.018
regulation of peptidase activity GO:0052547 23 0.018
photoreceptor cell fate specification GO:0043704 1 0.018
positive regulation of cell migration GO:0030335 11 0.018
response to amino acid GO:0043200 2 0.018
ceramide biosynthetic process GO:0046513 1 0.017
negative regulation of leukocyte differentiation GO:1902106 1 0.017
negative regulation of protein maturation GO:1903318 10 0.017
positive regulation of cell adhesion GO:0045785 1 0.017
positive regulation of cellular catabolic process GO:0031331 3 0.017
gabaergic neuron differentiation GO:0097154 2 0.017
formation of primary germ layer GO:0001704 62 0.017
generation of neurons GO:0048699 385 0.017
Worm
stem cell proliferation GO:0072089 4 0.017
mesoderm development GO:0007498 88 0.017
telencephalon development GO:0021537 14 0.017
embryonic digestive tract morphogenesis GO:0048557 3 0.017
oxoacid metabolic process GO:0043436 31 0.017
cellular biosynthetic process GO:0044249 286 0.017
specification of axis polarity GO:0065001 4 0.016
regulation of response to extracellular stimulus GO:0032104 1 0.016
negative regulation of apoptotic process GO:0043066 55 0.016
sensory organ morphogenesis GO:0090596 200 0.016
cardiac ventricle development GO:0003231 9 0.015
positive regulation of molecular function GO:0044093 33 0.015
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.015
hematopoietic stem cell migration GO:0035701 4 0.015
interspecies interaction between organisms GO:0044419 4 0.015
lateral ventricle development GO:0021670 1 0.015
regulation of cellular component movement GO:0051270 55 0.015
positive regulation of skeletal muscle tissue development GO:0048643 1 0.015
positive regulation of signaling GO:0023056 56 0.015
positive regulation of cell division GO:0051781 2 0.015
regulation of proteolysis GO:0030162 24 0.015
positive regulation of cellular component organization GO:0051130 13 0.015
regeneration GO:0031099 91 0.015
regulation of receptor activity GO:0010469 2 0.015
small molecule biosynthetic process GO:0044283 16 0.015
photoreceptor cell differentiation GO:0046530 55 0.015
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.015
neuron migration GO:0001764 22 0.015
intracellular signal transduction GO:0035556 85 0.014
behavior GO:0007610 74 0.014
positive regulation of protein metabolic process GO:0051247 23 0.014
regulation of endopeptidase activity GO:0052548 23 0.014
camera type eye development GO:0043010 222 0.014
positive regulation of cell differentiation GO:0045597 30 0.014
neuron projection extension GO:1990138 45 0.014
cellular protein catabolic process GO:0044257 4 0.014
chemosensory behavior GO:0007635 1 0.014
regulation of catalytic activity GO:0050790 55 0.014
positive regulation of response to wounding GO:1903036 5 0.014
positive regulation of apoptotic process GO:0043065 29 0.014
myoblast fusion GO:0007520 10 0.014
cerebellar granular layer formation GO:0021684 3 0.014
cellular response to drug GO:0035690 1 0.014
cell substrate adhesion GO:0031589 4 0.013
chondrocyte development GO:0002063 4 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
skeletal system morphogenesis GO:0048705 102 0.013
extracellular structure organization GO:0043062 27 0.013
positive regulation of smoothened signaling pathway GO:0045880 5 0.013
cell type specific apoptotic process GO:0097285 22 0.013
phosphorus metabolic process GO:0006793 109 0.013
regulation of cellular component organization GO:0051128 86 0.013
phosphorylation GO:0016310 69 0.013
regulation of heart growth GO:0060420 2 0.013
regulation of erk1 and erk2 cascade GO:0070372 4 0.013
positive regulation of cellular component movement GO:0051272 11 0.012
axon midline choice point recognition GO:0016199 4 0.012
skin morphogenesis GO:0043589 7 0.012
positive regulation of cell projection organization GO:0031346 9 0.012
regulation of protein metabolic process GO:0051246 56 0.012
negative regulation of cellular component movement GO:0051271 18 0.012
nucleobase containing compound metabolic process GO:0006139 274 0.012
regulation of cell migration GO:0030334 40 0.012
muscle tissue development GO:0060537 110 0.012
negative regulation of granulocyte chemotaxis GO:0071623 3 0.012
wound healing GO:0042060 90 0.012
embryonic digestive tract development GO:0048566 4 0.012
nuclear transport GO:0051169 4 0.012
midbrain hindbrain boundary development GO:0030917 23 0.012
negative regulation of epithelial cell migration GO:0010633 1 0.012
rostrocaudal neural tube patterning GO:0021903 29 0.012
negative regulation of cell differentiation GO:0045596 46 0.012
lipid storage GO:0019915 1 0.012
positive regulation of neuron differentiation GO:0045666 12 0.012
positive regulation of phosphate metabolic process GO:0045937 21 0.012
cerebellar granule cell differentiation GO:0021707 3 0.012
positive regulation of immune system process GO:0002684 17 0.012
positive regulation of cell proliferation GO:0008284 15 0.011
oocyte maturation GO:0001556 4 0.011
embryonic skeletal joint development GO:0072498 3 0.011
lymphangiogenesis GO:0001946 25 0.011
fertilization GO:0009566 3 0.011
convergent extension GO:0060026 118 0.011
neurological system process GO:0050877 62 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.011
blood circulation GO:0008015 87 0.011
regulation of binding GO:0051098 3 0.011
cardiac muscle tissue development GO:0048738 48 0.011
regulation of neuron death GO:1901214 18 0.011
regulation of cysteine type endopeptidase activity GO:2000116 21 0.011
embryonic skeletal system development GO:0048706 97 0.011
regulation of multicellular organismal development GO:2000026 223 0.011
positive regulation of cell substrate adhesion GO:0010811 1 0.011
regulation of hormone secretion GO:0046883 2 0.011
intracellular mrna localization GO:0008298 1 0.011
hormone transport GO:0009914 2 0.011
positive regulation of nervous system development GO:0051962 25 0.011
establishment of localization in cell GO:0051649 77 0.011
protein phosphorylation GO:0006468 47 0.011
regulation of reproductive process GO:2000241 4 0.011
single organism behavior GO:0044708 24 0.011
enzyme linked receptor protein signaling pathway GO:0007167 106 0.011
positive regulation of leukocyte migration GO:0002687 2 0.011
spermatid development GO:0007286 2 0.011
protein import GO:0017038 3 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
establishment of protein localization to organelle GO:0072594 4 0.011
neural precursor cell proliferation GO:0061351 20 0.011
macromolecular complex subunit organization GO:0043933 74 0.011
posttranscriptional regulation of gene expression GO:0010608 14 0.010
regulation of cellular metabolic process GO:0031323 320 0.010
ventral spinal cord interneuron fate commitment GO:0060579 3 0.010
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.010
atrioventricular valve formation GO:0003190 3 0.010
negative regulation of cytoplasmic transport GO:1903650 2 0.010
nucleocytoplasmic transport GO:0006913 4 0.010
cellular component movement GO:0006928 335 0.010
Worm
cardiac cell fate commitment GO:0060911 1 0.010
negative regulation of cell migration GO:0030336 17 0.010
chemotaxis GO:0006935 104 0.010
Worm
response to wounding GO:0009611 116 0.010
negative regulation of wnt signaling pathway GO:0030178 30 0.010

spon1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
bone development disease DOID:0080006 0 0.043
bone disease DOID:0080001 0 0.043
disease of anatomical entity DOID:7 0 0.043
dysostosis DOID:1934 0 0.043
musculoskeletal system disease DOID:17 0 0.043
connective tissue disease DOID:65 0 0.043
synostosis DOID:11971 0 0.043
disease of cellular proliferation DOID:14566 0 0.010