Danio rerio

26 known processes

stk11

serine/threonine kinase 11

(Aliases: wu:fj61a05,zgc:110180)

stk11 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular biosynthetic process GO:0044249 286 0.396
cellular component morphogenesis GO:0032989 336 0.369
Mouse
organic substance biosynthetic process GO:1901576 289 0.366
gene expression GO:0010467 252 0.271
protein localization to nucleus GO:0034504 3 0.262
biosynthetic process GO:0009058 294 0.237
cellular macromolecule biosynthetic process GO:0034645 224 0.234
cellular aromatic compound metabolic process GO:0006725 295 0.211
aromatic compound biosynthetic process GO:0019438 217 0.199
cellular macromolecule metabolic process GO:0044260 391 0.192
Human Mouse Worm
multicellular organism growth GO:0035264 4 0.192
sensory organ development GO:0007423 393 0.184
nitrogen compound metabolic process GO:0006807 319 0.182
cellular nitrogen compound biosynthetic process GO:0044271 218 0.182
intracellular signal transduction GO:0035556 85 0.173
Human Mouse Fly
cell projection morphogenesis GO:0048858 244 0.173
Mouse
rna biosynthetic process GO:0032774 181 0.167
nucleobase containing compound metabolic process GO:0006139 274 0.167
regulation of primary metabolic process GO:0080090 311 0.165
Human Mouse
nucleobase containing compound biosynthetic process GO:0034654 205 0.164
protein targeting to nucleus GO:0044744 3 0.154
nucleic acid templated transcription GO:0097659 181 0.143
response to external stimulus GO:0009605 264 0.142
nuclear transport GO:0051169 4 0.134
cellular nitrogen compound metabolic process GO:0034641 290 0.132
heterocycle biosynthetic process GO:0018130 215 0.129
cellular component movement GO:0006928 335 0.129
regulation of establishment of protein localization GO:0070201 4 0.126
transcription dna templated GO:0006351 181 0.125
eye development GO:0001654 277 0.124
positive regulation of biological process GO:0048518 253 0.122
Human Mouse Worm Fly
regulation of rna biosynthetic process GO:2001141 213 0.118
digestive system development GO:0055123 289 0.117
regulation of nitrogen compound metabolic process GO:0051171 251 0.117
growth GO:0040007 174 0.114
Mouse
positive regulation of transport GO:0051050 2 0.114
immune system process GO:0002376 241 0.111
Mouse
nuclear import GO:0051170 3 0.109
regulation of signal transduction GO:0009966 225 0.107
Human Mouse Fly
regulation of biological quality GO:0065008 263 0.106
modification dependent macromolecule catabolic process GO:0043632 3 0.105
regulation of response to nutrient levels GO:0032107 1 0.105
rna metabolic process GO:0016070 219 0.104
regulation of signaling GO:0023051 235 0.103
Human Mouse Fly
protein import GO:0017038 3 0.103
regulation of multicellular organismal development GO:2000026 223 0.102
Mouse Worm
regulation of macromolecule biosynthetic process GO:0010556 225 0.101
single organism nuclear import GO:1902593 3 0.101
neuron development GO:0048666 262 0.100
Mouse
larval development GO:0002164 2 0.100
Worm
regulation of biosynthetic process GO:0009889 250 0.099
adult behavior GO:0030534 2 0.098
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.098
cell projection organization GO:0030030 284 0.096
Mouse
single organism transport GO:0044765 206 0.094
cellular protein catabolic process GO:0044257 4 0.092
regulation of nucleic acid templated transcription GO:1903506 213 0.091
neuron projection development GO:0031175 180 0.091
Mouse
negative regulation of cellular process GO:0048523 283 0.090
Human Mouse Fly
digestive tract development GO:0048565 265 0.089
regulation of protein transport GO:0051223 3 0.088
regulation of response to stimulus GO:0048583 269 0.087
Human Mouse Fly
regulation of apoptotic process GO:0042981 98 0.087
Fly
hematopoietic or lymphoid organ development GO:0048534 191 0.087
Mouse
muscle structure development GO:0061061 196 0.085
regulation of metabolic process GO:0019222 359 0.085
Human Mouse Fly
regulation of macromolecule metabolic process GO:0060255 317 0.079
Human Mouse
cell morphogenesis involved in differentiation GO:0000904 195 0.078
Mouse
regulation of transcription dna templated GO:0006355 213 0.078
signal transduction GO:0007165 455 0.078
Human Mouse Fly
developmental growth GO:0048589 166 0.076
Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.074
Mouse
nucleocytoplasmic transport GO:0006913 4 0.072
establishment of protein localization to organelle GO:0072594 4 0.072
negative regulation of macromolecule metabolic process GO:0010605 76 0.071
organic cyclic compound biosynthetic process GO:1901362 223 0.071
modification dependent protein catabolic process GO:0019941 3 0.071
regulation of rna metabolic process GO:0051252 224 0.071
response to stress GO:0006950 263 0.071
Worm Fly
regulation of multicellular organism growth GO:0040014 4 0.070
negative regulation of gene expression GO:0010629 65 0.070
positive regulation of catabolic process GO:0009896 4 0.069
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.068
liver development GO:0001889 96 0.068
regulation of cell differentiation GO:0045595 142 0.068
Mouse
hemopoiesis GO:0030097 183 0.068
Mouse
regulation of gene expression GO:0010468 265 0.068
microtubule based movement GO:0007018 33 0.065
cell migration GO:0016477 237 0.064
protein metabolic process GO:0019538 183 0.064
Human Mouse Worm
negative regulation of response to stimulus GO:0048585 104 0.063
cellular response to biotic stimulus GO:0071216 3 0.063
hepaticobiliary system development GO:0061008 98 0.063
heterocycle metabolic process GO:0046483 290 0.063
organic cyclic compound metabolic process GO:1901360 301 0.063
nucleic acid metabolic process GO:0090304 244 0.062
positive regulation of cell cycle GO:0045787 3 0.061
negative regulation of rna metabolic process GO:0051253 48 0.060
macromolecule biosynthetic process GO:0009059 227 0.060
cellular response to external stimulus GO:0071496 2 0.059
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.059
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.059
single organism metabolic process GO:0044710 217 0.059
Fly
cell morphogenesis GO:0000902 289 0.058
Mouse
system process GO:0003008 185 0.057
negative regulation of ras protein signal transduction GO:0046580 1 0.057
cellular response to nutrient levels GO:0031669 2 0.056
positive regulation of cellular catabolic process GO:0031331 3 0.055
neuron differentiation GO:0030182 353 0.055
Mouse
lateral inhibition GO:0046331 1 0.055
regulation of response to extracellular stimulus GO:0032104 1 0.054
microtubule based process GO:0007017 60 0.054
Fly
camera type eye development GO:0043010 222 0.054
maintenance of location GO:0051235 4 0.053
heart looping GO:0001947 94 0.052
regulation of developmental process GO:0050793 247 0.052
Mouse Worm
tube morphogenesis GO:0035239 349 0.052
regulation of cell communication GO:0010646 232 0.052
Human Mouse Fly
morphogenesis of an epithelium GO:0002009 333 0.051
Fly
locomotion GO:0040011 313 0.051
Worm
cellular protein metabolic process GO:0044267 129 0.050
Human Mouse Worm
organelle organization GO:0006996 227 0.049
Fly
cellular response to starvation GO:0009267 1 0.049
aging GO:0007568 2 0.049
Worm Fly
homeostatic process GO:0042592 142 0.049
ubiquitin dependent protein catabolic process GO:0006511 3 0.048
regulation of protein catabolic process GO:0042176 1 0.047
axon development GO:0061564 166 0.047
Mouse
cell surface receptor signaling pathway GO:0007166 325 0.045
Human Mouse
protein import into nucleus GO:0006606 3 0.045
cellular response to extracellular stimulus GO:0031668 2 0.044
regulation of protein import into nucleus GO:0042306 2 0.044
cell part morphogenesis GO:0032990 246 0.044
Mouse
negative regulation of metabolic process GO:0009892 86 0.044
regulation of synapse organization GO:0050807 3 0.044
programmed cell death GO:0012501 119 0.043
Human Fly
response to chemical GO:0042221 320 0.043
Human Mouse
cellular amino acid metabolic process GO:0006520 7 0.042
organonitrogen compound metabolic process GO:1901564 74 0.042
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.042
cellular amine metabolic process GO:0044106 2 0.040
positive regulation of protein kinase b signaling GO:0051897 1 0.040
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.039
cellular localization GO:0051641 97 0.038
Mouse Fly
immune system development GO:0002520 191 0.038
Mouse
cellular component biogenesis GO:0044085 178 0.038
Mouse Fly
negative regulation of signaling GO:0023057 96 0.038
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.038
small molecule metabolic process GO:0044281 77 0.037
negative regulation of biological process GO:0048519 304 0.036
Human Mouse Fly
blood vessel morphogenesis GO:0048514 216 0.036
embryo development ending in birth or egg hatching GO:0009792 271 0.036
Fly
cell motility GO:0048870 244 0.035
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.035
Mouse Fly
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.035
positive regulation of cellular metabolic process GO:0031325 94 0.035
Human Mouse
regulation of cytoplasmic transport GO:1903649 4 0.035
sex determination GO:0007530 1 0.034
response to abiotic stimulus GO:0009628 122 0.034
Mouse
amine metabolic process GO:0009308 2 0.034
pigment granule localization GO:0051875 25 0.034
positive regulation of metabolic process GO:0009893 108 0.033
Human Mouse
regulation of cellular component organization GO:0051128 86 0.033
Mouse
regulation of organelle assembly GO:1902115 4 0.033
negative regulation of rna biosynthetic process GO:1902679 45 0.033
organic substance catabolic process GO:1901575 28 0.033
regulation of catalytic activity GO:0050790 55 0.033
Human Mouse
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.032
nonmotile primary cilium assembly GO:0035058 2 0.032
lipid storage GO:0019915 1 0.032
positive regulation of immune effector process GO:0002699 3 0.032
regulation of cellular amine metabolic process GO:0033238 0 0.032
specification of symmetry GO:0009799 204 0.031
negative regulation of epithelial cell proliferation GO:0050680 1 0.031
Mouse
oxoacid metabolic process GO:0043436 31 0.031
gland development GO:0048732 143 0.031
Mouse
localization of cell GO:0051674 244 0.030
meiotic nuclear division GO:0007126 4 0.029
pigment granule transport GO:0051904 19 0.029
regulation of protein targeting GO:1903533 2 0.029
positive regulation of secretion GO:0051047 1 0.029
brain development GO:0007420 293 0.029
protein modification process GO:0036211 100 0.028
Human Mouse Worm
death GO:0016265 121 0.028
Human Fly
regulation of cellular biosynthetic process GO:0031326 245 0.028
establishment of localization GO:0051234 244 0.028
single organism biosynthetic process GO:0044711 71 0.027
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.027
gamete generation GO:0007276 33 0.027
Mouse Fly
atp catabolic process GO:0006200 4 0.026
regulation of intracellular protein transport GO:0033157 3 0.026
positive regulation of multicellular organismal process GO:0051240 52 0.026
Mouse Worm
positive regulation of cellular process GO:0048522 201 0.026
Human Mouse Fly
regulation of cellular ketone metabolic process GO:0010565 7 0.026
metal ion transport GO:0030001 58 0.026
positive regulation of cellular component biogenesis GO:0044089 3 0.025
cellular response to organic substance GO:0071310 105 0.025
Human Mouse
transport GO:0006810 220 0.025
alpha amino acid metabolic process GO:1901605 3 0.025
guanosine containing compound catabolic process GO:1901069 2 0.025
cellular ketone metabolic process GO:0042180 11 0.025
positive regulation of molecular function GO:0044093 33 0.025
Human Mouse
regulation of cell proliferation GO:0042127 37 0.025
Human Mouse
apoptotic process GO:0006915 116 0.025
Human Fly
extrinsic apoptotic signaling pathway GO:0097191 3 0.025
myeloid cell development GO:0061515 32 0.025
generation of neurons GO:0048699 385 0.025
Mouse Worm Fly
response to carbohydrate GO:0009743 3 0.024
regulation of multicellular organismal process GO:0051239 277 0.024
Mouse Worm
cellular protein modification process GO:0006464 100 0.024
Human Mouse Worm
synaptic growth at neuromuscular junction GO:0051124 2 0.024
stem cell division GO:0017145 1 0.024
Worm Fly
regulation of synapse assembly GO:0051963 3 0.024
dna templated transcription initiation GO:0006352 1 0.024
negative regulation of signal transduction GO:0009968 94 0.024
locomotor rhythm GO:0045475 3 0.024
proteolysis GO:0006508 38 0.024
response to drug GO:0042493 3 0.023
cellular component disassembly GO:0022411 1 0.023
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.023
cell cycle process GO:0022402 53 0.023
Human Worm Fly
regulation of blood vessel size GO:0050880 2 0.023
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.023
regulation of protein localization to nucleus GO:1900180 2 0.023
organic acid metabolic process GO:0006082 31 0.023
negative regulation of intracellular signal transduction GO:1902532 22 0.023
taxis GO:0042330 109 0.023
regulation of cell cycle GO:0051726 52 0.023
Human Worm
positive regulation of chromosome organization GO:2001252 1 0.022
regulation of carbohydrate metabolic process GO:0006109 4 0.022
axonogenesis GO:0007409 152 0.022
Mouse
multi organism reproductive process GO:0044703 36 0.022
Mouse Fly
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.022
vasculature development GO:0001944 278 0.022
Mouse
neuron projection morphogenesis GO:0048812 161 0.022
Mouse
negative regulation of cell communication GO:0010648 96 0.022
neuron projection guidance GO:0097485 86 0.022
regulation of cell shape GO:0008360 1 0.022
phosphorus metabolic process GO:0006793 109 0.022
Human Mouse Worm Fly
intracellular transport GO:0046907 32 0.022
peptidyl serine phosphorylation GO:0018105 1 0.022
regulation of metal ion transport GO:0010959 4 0.022
determination of heart left right asymmetry GO:0061371 117 0.021
regulation of protein ubiquitination GO:0031396 3 0.021
female gonad development GO:0008585 4 0.021
skeletal system development GO:0001501 181 0.021
somatic muscle development GO:0007525 4 0.021
cell proliferation GO:0008283 80 0.021
Human Mouse Worm Fly
negative regulation of transcription dna templated GO:0045892 45 0.021
gene silencing GO:0016458 4 0.021
gtp metabolic process GO:0046039 4 0.021
pigmentation GO:0043473 85 0.021
positive regulation of gtpase activity GO:0043547 1 0.021
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.021
Mouse
regulation of programmed cell death GO:0043067 101 0.021
Fly
multicellular organismal reproductive process GO:0048609 35 0.020
Mouse Fly
brain morphogenesis GO:0048854 18 0.020
mitotic cell cycle process GO:1903047 48 0.020
Fly
macromolecular complex disassembly GO:0032984 1 0.020
head development GO:0060322 303 0.020
positive regulation of nucleic acid templated transcription GO:1903508 57 0.020
macromolecular complex subunit organization GO:0043933 74 0.020
Mouse Fly
regulation of proteolysis GO:0030162 24 0.020
blood vessel development GO:0001568 246 0.020
cellular response to chemical stimulus GO:0070887 157 0.020
Human Mouse
cellular response to stress GO:0033554 62 0.020
Fly
protein k48 linked ubiquitination GO:0070936 1 0.020
regulation of organ growth GO:0046620 3 0.020
angiogenesis GO:0001525 158 0.020
positive regulation of dna metabolic process GO:0051054 1 0.020
cellular response to lipopolysaccharide GO:0071222 3 0.020
cellular component assembly involved in morphogenesis GO:0010927 107 0.020
negative regulation of protein phosphorylation GO:0001933 4 0.019
regionalization GO:0003002 274 0.019
Fly
axon guidance GO:0007411 86 0.019
single organism localization GO:1902578 225 0.019
Fly
gtp catabolic process GO:0006184 2 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.019
rna splicing GO:0008380 16 0.019
cellular carbohydrate metabolic process GO:0044262 4 0.019
positive regulation of cytokine production GO:0001819 2 0.019
catabolic process GO:0009056 32 0.019
cellular response to decreased oxygen levels GO:0036294 1 0.019
viral process GO:0016032 1 0.018
regulation of binding GO:0051098 3 0.018
regulation of histone methylation GO:0031060 3 0.018
regulation of nucleotide catabolic process GO:0030811 2 0.018
anterior posterior pattern specification GO:0009952 152 0.018
Fly
response to growth factor GO:0070848 39 0.018
Human Mouse
cell substrate junction assembly GO:0007044 2 0.018
positive regulation of response to stimulus GO:0048584 80 0.018
Human Mouse
blood circulation GO:0008015 87 0.018
regulation of purine nucleotide catabolic process GO:0033121 2 0.018
muscle organ development GO:0007517 101 0.018
proteasomal protein catabolic process GO:0010498 2 0.018
chordate embryonic development GO:0043009 271 0.018
single organism organelle organization GO:1902589 199 0.018
Fly
regulation of cell activation GO:0050865 1 0.018
phosphate containing compound metabolic process GO:0006796 108 0.018
Human Mouse Worm Fly
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
digestive tract morphogenesis GO:0048546 231 0.018
macromolecule modification GO:0043412 111 0.018
Human Mouse Worm
negative regulation of apoptotic process GO:0043066 55 0.018
retina development in camera type eye GO:0060041 146 0.018
tissue homeostasis GO:0001894 25 0.018
Mouse
phosphatidylinositol mediated signaling GO:0048015 2 0.018
positive regulation of leukocyte differentiation GO:1902107 1 0.017
regulation of reproductive process GO:2000241 4 0.017
Mouse
regulation of cellular protein catabolic process GO:1903362 1 0.017
lipid metabolic process GO:0006629 52 0.017
homeostasis of number of cells GO:0048872 62 0.017
transcription from rna polymerase ii promoter GO:0006366 80 0.017
endosomal transport GO:0016197 2 0.017
regulation of epithelial cell proliferation GO:0050678 3 0.017
Mouse
multicellular organismal homeostasis GO:0048871 29 0.017
regulation of nucleoside metabolic process GO:0009118 2 0.017
striated muscle cell differentiation GO:0051146 129 0.017
embryonic heart tube morphogenesis GO:0003143 108 0.017
negative regulation of programmed cell death GO:0043069 58 0.017
spindle assembly GO:0051225 2 0.017
single organism intracellular transport GO:1902582 25 0.016
convergent extension GO:0060026 118 0.016
ion homeostasis GO:0050801 41 0.016
double strand break repair GO:0006302 3 0.016
regulation of protein complex assembly GO:0043254 3 0.016
protein polyubiquitination GO:0000209 4 0.016
connective tissue development GO:0061448 99 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.016
transmembrane transport GO:0055085 120 0.016
negative regulation of map kinase activity GO:0043407 2 0.016
sexual reproduction GO:0019953 36 0.016
Mouse Fly
neural retina development GO:0003407 49 0.016
retina homeostasis GO:0001895 12 0.016
response to nutrient GO:0007584 3 0.016
centrosome organization GO:0051297 1 0.016
ovulation cycle GO:0042698 2 0.016
reproductive process GO:0022414 40 0.016
Mouse Fly
rna localization GO:0006403 4 0.016
Fly
cellular response to radiation GO:0071478 4 0.016
negative regulation of intracellular transport GO:0032387 3 0.016
neuroblast proliferation GO:0007405 2 0.016
Worm Fly
negative regulation of protein transport GO:0051224 3 0.016
response to organic substance GO:0010033 153 0.015
Human Mouse
mitotic cell cycle GO:0000278 64 0.015
Fly
regulation of oocyte development GO:0060281 3 0.015
multi organism process GO:0051704 134 0.015
Mouse Fly
negative regulation of biosynthetic process GO:0009890 55 0.015
autophagy GO:0006914 4 0.015
regulation of gtp catabolic process GO:0033124 2 0.015
regulation of meiotic cell cycle GO:0051445 1 0.015
nucleoside monophosphate catabolic process GO:0009125 4 0.015
regulation of protein maturation GO:1903317 10 0.015
negative regulation of nucleic acid templated transcription GO:1903507 45 0.015
energy reserve metabolic process GO:0006112 2 0.015
histone h3 k4 methylation GO:0051568 2 0.015
central nervous system development GO:0007417 387 0.015
cartilage development GO:0051216 96 0.015
eye photoreceptor cell development GO:0042462 30 0.014
regulation of gene expression epigenetic GO:0040029 11 0.014
compound eye development GO:0048749 2 0.014
negative regulation of cellular metabolic process GO:0031324 77 0.014
melanosome transport GO:0032402 19 0.014
cellular response to molecule of bacterial origin GO:0071219 3 0.014
circulatory system process GO:0003013 87 0.014
convergent extension involved in gastrulation GO:0060027 71 0.014
tissue remodeling GO:0048771 4 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.014
Human Mouse
negative regulation of protein import into nucleus GO:0042308 2 0.014
positive regulation of transcription dna templated GO:0045893 57 0.014
ribonucleoside monophosphate catabolic process GO:0009158 4 0.014
regulation of cytokine production GO:0001817 3 0.014
cilium morphogenesis GO:0060271 85 0.014
cytokinesis GO:0000910 3 0.014
Worm
cognition GO:0050890 1 0.014
chromatin modification GO:0016568 21 0.014
response to ketone GO:1901654 1 0.014
cytoskeleton dependent cytokinesis GO:0061640 3 0.014
Worm
eye photoreceptor cell differentiation GO:0001754 45 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.014
cell matrix adhesion GO:0007160 4 0.014
epithelial tube morphogenesis GO:0060562 148 0.014
epidermis development GO:0008544 48 0.014
regulation of cellular protein metabolic process GO:0032268 52 0.014
Human Mouse
pancreas development GO:0031016 84 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
negative regulation of histone modification GO:0031057 1 0.014
protein phosphorylation GO:0006468 47 0.014
Human Mouse Worm
determination of bilateral symmetry GO:0009855 204 0.014
ovulation cycle process GO:0022602 2 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.014
ras protein signal transduction GO:0007265 7 0.013
regulation of cell fate commitment GO:0010453 22 0.013
protein localization GO:0008104 40 0.013
Worm
positive regulation of cell adhesion GO:0045785 1 0.013
guanosine containing compound metabolic process GO:1901068 4 0.013
ameboidal type cell migration GO:0001667 143 0.013
chemotaxis GO:0006935 104 0.013
negative regulation of cell death GO:0060548 60 0.013
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
Mouse
photoreceptor cell differentiation GO:0046530 55 0.013
osteoclast development GO:0036035 1 0.013
gastrulation GO:0007369 208 0.013
regulation of molecular function GO:0065009 70 0.013
Human Mouse
membrane fusion GO:0061025 2 0.013
regulation of transport GO:0051049 45 0.013
regulation of cell fate specification GO:0042659 20 0.013
exocrine pancreas development GO:0031017 28 0.013
endocrine process GO:0050886 2 0.013
microtubule organizing center organization GO:0031023 1 0.013
cell fate commitment GO:0045165 99 0.013
Worm Fly
smooth muscle contraction GO:0006939 2 0.013
cellular component assembly GO:0022607 170 0.013
Mouse Fly
stem cell proliferation GO:0072089 4 0.013
Worm Fly
positive regulation of cell activation GO:0050867 1 0.013
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.013
cellular response to dna damage stimulus GO:0006974 24 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.013
retina layer formation GO:0010842 24 0.013
carbohydrate derivative metabolic process GO:1901135 61 0.013
establishment of melanosome localization GO:0032401 19 0.013
positive regulation of secretion by cell GO:1903532 1 0.012
axis specification GO:0009798 43 0.012
Fly
nuclear export GO:0051168 1 0.012
dna biosynthetic process GO:0071897 3 0.012
determination of left right symmetry GO:0007368 179 0.012
behavior GO:0007610 74 0.012
cell cell signaling GO:0007267 52 0.012
regulation of gtpase activity GO:0043087 2 0.012
photoreceptor cell maintenance GO:0045494 11 0.012
response to food GO:0032094 1 0.012
regulation of erk1 and erk2 cascade GO:0070372 4 0.012
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.012
somitogenesis GO:0001756 87 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.012
Human Mouse
cell adhesion mediated by integrin GO:0033627 1 0.012
forebrain regionalization GO:0021871 4 0.012
positive regulation of apoptotic signaling pathway GO:2001235 1 0.012
positive regulation of gtp catabolic process GO:0033126 1 0.012
regulation of microtubule based movement GO:0060632 3 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
negative regulation of mrna metabolic process GO:1903312 3 0.012
lymphocyte proliferation GO:0046651 1 0.012
female sex differentiation GO:0046660 4 0.012
heart development GO:0007507 313 0.012
adherens junction assembly GO:0034333 1 0.012
single organism cellular localization GO:1902580 46 0.012
Fly
negative regulation of cytoplasmic transport GO:1903650 2 0.012
regulation of cell death GO:0010941 103 0.012
Fly
regulation of blood pressure GO:0008217 1 0.012
primary neural tube formation GO:0014020 1 0.011
positive regulation of neuron death GO:1901216 1 0.011
macromolecule localization GO:0033036 54 0.011
Worm Fly
negative regulation of kinase activity GO:0033673 4 0.011
exocytosis GO:0006887 1 0.011
positive regulation of multi organism process GO:0043902 3 0.011
cellular response to endogenous stimulus GO:0071495 68 0.011
Human Mouse
regulation of protein binding GO:0043393 3 0.011
regulation of synaptic plasticity GO:0048167 1 0.011
cilium movement involved in cell motility GO:0060294 3 0.011
regulation of autophagy GO:0010506 3 0.011
b cell differentiation GO:0030183 1 0.011
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.011
regulation of circadian rhythm GO:0042752 4 0.011
negative regulation of intracellular protein transport GO:0090317 3 0.011
negative regulation of synapse assembly GO:0051964 2 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.011
protein modification by small protein conjugation or removal GO:0070647 14 0.011
cellular protein localization GO:0034613 20 0.011
positive regulation of histone modification GO:0031058 1 0.011
regulation of localization GO:0032879 104 0.011
interspecies interaction between organisms GO:0044419 4 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.011
protein complex subunit organization GO:0071822 46 0.011
Mouse Fly
negative regulation of multi organism process GO:0043901 3 0.011
establishment of vesicle localization GO:0051650 24 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
cellular lipid metabolic process GO:0044255 36 0.011
multi organism cellular process GO:0044764 2 0.011
hormone secretion GO:0046879 2 0.011
cell death GO:0008219 121 0.011
Human Fly
regulation of membrane potential GO:0042391 23 0.010
peptidyl serine modification GO:0018209 2 0.010
central nervous system neuron differentiation GO:0021953 74 0.010
regulation of cell motility GO:2000145 46 0.010
nucleic acid transport GO:0050657 2 0.010
stem cell fate commitment GO:0048865 1 0.010
establishment or maintenance of cell polarity GO:0007163 29 0.010
Mouse Worm Fly
inner ear development GO:0048839 126 0.010
dna templated transcription elongation GO:0006354 3 0.010
cellular pigmentation GO:0033059 30 0.010

stk11 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.036
Human
disease of cellular proliferation DOID:14566 0 0.036
Human
organ system cancer DOID:0050686 0 0.030
Human
disease of anatomical entity DOID:7 0 0.030
Human
nervous system disease DOID:863 0 0.030