Danio rerio

0 known processes

stxbp2

syntaxin binding protein 2

(Aliases: zgc:85807)

stxbp2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism localization GO:1902578 225 0.226
Human Worm Fly
hemopoiesis GO:0030097 183 0.225
immune system development GO:0002520 191 0.220
protein complex localization GO:0031503 1 0.200
maintenance of location GO:0051235 4 0.185
cellular macromolecule metabolic process GO:0044260 391 0.182
regulation of intracellular protein transport GO:0033157 3 0.180
larval development GO:0002164 2 0.175
regulation of developmental process GO:0050793 247 0.169
Fly
cellular modified amino acid metabolic process GO:0006575 3 0.145
heterocycle metabolic process GO:0046483 290 0.142
regulation of biological quality GO:0065008 263 0.138
Worm Fly
organelle organization GO:0006996 227 0.133
apoptotic process GO:0006915 116 0.128
nuclear transport GO:0051169 4 0.124
regulation of multicellular organism growth GO:0040014 4 0.122
single organism organelle organization GO:1902589 199 0.117
positive regulation of transport GO:0051050 2 0.115
Worm
nucleobase containing compound biosynthetic process GO:0034654 205 0.113
multicellular organism growth GO:0035264 4 0.108
establishment of protein localization to organelle GO:0072594 4 0.108
negative regulation of cellular process GO:0048523 283 0.104
cell morphogenesis GO:0000902 289 0.103
viral process GO:0016032 1 0.102
nitrogen compound metabolic process GO:0006807 319 0.101
protein import into nucleus GO:0006606 3 0.101
cellular response to starvation GO:0009267 1 0.093
nuclear import GO:0051170 3 0.089
nucleocytoplasmic transport GO:0006913 4 0.089
regulation of multicellular organismal process GO:0051239 277 0.087
Fly
regulation of protein import into nucleus GO:0042306 2 0.085
response to biotic stimulus GO:0009607 97 0.084
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.083
positive regulation of cellular process GO:0048522 201 0.082
Worm
transport GO:0006810 220 0.082
Human Worm Fly
neuron development GO:0048666 262 0.082
cell part morphogenesis GO:0032990 246 0.079
actin polymerization or depolymerization GO:0008154 2 0.076
carboxylic acid metabolic process GO:0019752 22 0.076
lipid storage GO:0019915 1 0.076
regulation of signaling GO:0023051 235 0.075
Worm
regulation of protein complex assembly GO:0043254 3 0.074
regulation of establishment of protein localization GO:0070201 4 0.073
single organism transport GO:0044765 206 0.071
Human Worm Fly
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.070
cellular amino acid metabolic process GO:0006520 7 0.070
multi organism process GO:0051704 134 0.070
Fly
organic cyclic compound metabolic process GO:1901360 301 0.069
regulation of biosynthetic process GO:0009889 250 0.067
cellular biosynthetic process GO:0044249 286 0.066
meiotic nuclear division GO:0007126 4 0.066
single organism nuclear import GO:1902593 3 0.065
nucleobase containing compound metabolic process GO:0006139 274 0.065
regulation of macromolecule biosynthetic process GO:0010556 225 0.065
regulation of protein transport GO:0051223 3 0.064
nucleotide biosynthetic process GO:0009165 21 0.064
intracellular signal transduction GO:0035556 85 0.063
regulation of protein targeting GO:1903533 2 0.063
cellular response to external stimulus GO:0071496 2 0.062
immune system process GO:0002376 241 0.061
Human
regulation of transcription dna templated GO:0006355 213 0.061
protein localization to nucleus GO:0034504 3 0.061
cellular response to nutrient levels GO:0031669 2 0.060
regulation of reproductive process GO:2000241 4 0.060
Fly
cellular aromatic compound metabolic process GO:0006725 295 0.059
biosynthetic process GO:0009058 294 0.058
regulation of cellular biosynthetic process GO:0031326 245 0.057
regulation of cytokine production GO:0001817 3 0.057
i kappab kinase nf kappab signaling GO:0007249 4 0.057
protein targeting to nucleus GO:0044744 3 0.056
developmental growth GO:0048589 166 0.056
peptide transport GO:0015833 1 0.055
regulation of cellular amine metabolic process GO:0033238 0 0.055
response to nutrient GO:0007584 3 0.055
cellular amide metabolic process GO:0043603 4 0.054
exocytosis GO:0006887 1 0.054
Human Worm
cellular amino acid biosynthetic process GO:0008652 2 0.053
production of molecular mediator of immune response GO:0002440 2 0.052
regulation of response to stimulus GO:0048583 269 0.052
regulation of establishment or maintenance of cell polarity GO:0032878 2 0.050
death GO:0016265 121 0.048
regulation of primary metabolic process GO:0080090 311 0.048
organonitrogen compound metabolic process GO:1901564 74 0.048
cellular component assembly GO:0022607 170 0.048
Fly
regulation of cellular metabolic process GO:0031323 320 0.047
negative regulation of biological process GO:0048519 304 0.047
neuron projection development GO:0031175 180 0.046
macromolecular complex subunit organization GO:0043933 74 0.046
cytoplasm organization GO:0007028 4 0.046
Fly
cell projection organization GO:0030030 284 0.045
organic substance biosynthetic process GO:1901576 289 0.045
protein import GO:0017038 3 0.044
positive regulation of cellular catabolic process GO:0031331 3 0.044
cellular component morphogenesis GO:0032989 336 0.043
phosphorylation GO:0016310 69 0.042
cardiac conduction GO:0061337 3 0.042
establishment of localization GO:0051234 244 0.042
Human Worm Fly
cell projection morphogenesis GO:0048858 244 0.041
cellular nitrogen compound metabolic process GO:0034641 290 0.041
regulation of gene expression GO:0010468 265 0.041
neuron differentiation GO:0030182 353 0.041
positive regulation of cell killing GO:0031343 2 0.041
protein polymerization GO:0051258 4 0.040
oxoacid metabolic process GO:0043436 31 0.040
heterocycle biosynthetic process GO:0018130 215 0.040
macroautophagy GO:0016236 1 0.040
positive regulation of cellular metabolic process GO:0031325 94 0.040
cellular response to lipopolysaccharide GO:0071222 3 0.039
response to external stimulus GO:0009605 264 0.039
peptide metabolic process GO:0006518 1 0.039
positive regulation of biological process GO:0048518 253 0.039
Worm
single organism cellular localization GO:1902580 46 0.038
Fly
regulation of cytoplasmic transport GO:1903649 4 0.038
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.038
regulation of metabolic process GO:0019222 359 0.038
homeostatic process GO:0042592 142 0.037
macromolecule biosynthetic process GO:0009059 227 0.037
guanosine containing compound catabolic process GO:1901069 2 0.036
axon development GO:0061564 166 0.036
aging GO:0007568 2 0.036
phosphate containing compound metabolic process GO:0006796 108 0.035
specification of organ identity GO:0010092 2 0.034
signal transduction GO:0007165 455 0.034
positive regulation of protein complex assembly GO:0031334 2 0.034
regulation of tube size GO:0035150 2 0.034
carbohydrate derivative biosynthetic process GO:1901137 43 0.034
ion transmembrane transport GO:0034220 91 0.033
multi organism cellular process GO:0044764 2 0.033
single organism metabolic process GO:0044710 217 0.033
mononuclear cell proliferation GO:0032943 1 0.032
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.032
regulation of nucleocytoplasmic transport GO:0046822 2 0.032
regulation of macromolecule metabolic process GO:0060255 317 0.032
endosomal transport GO:0016197 2 0.031
cellular response to extracellular stimulus GO:0031668 2 0.030
rna metabolic process GO:0016070 219 0.030
meiotic chromosome segregation GO:0045132 3 0.030
single organism membrane fusion GO:0044801 2 0.030
membrane invagination GO:0010324 1 0.030
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.030
regulation of cell communication GO:0010646 232 0.030
Worm
neuron projection morphogenesis GO:0048812 161 0.030
positive regulation of catabolic process GO:0009896 4 0.029
multicellular organism reproduction GO:0032504 35 0.029
Fly
positive regulation of cytokine production GO:0001819 2 0.029
guanosine containing compound metabolic process GO:1901068 4 0.029
cellular nitrogen compound biosynthetic process GO:0044271 218 0.029
macromolecule modification GO:0043412 111 0.029
lipid catabolic process GO:0016042 4 0.028
cellular protein complex assembly GO:0043623 19 0.028
gene expression GO:0010467 252 0.028
regulation of blood vessel size GO:0050880 2 0.027
oxidoreduction coenzyme metabolic process GO:0006733 1 0.027
regulation of nitrogen compound metabolic process GO:0051171 251 0.027
regulation of cellular amino acid metabolic process GO:0006521 0 0.027
myeloid cell differentiation GO:0030099 86 0.027
synaptic growth at neuromuscular junction GO:0051124 2 0.027
amine metabolic process GO:0009308 2 0.027
hematopoietic or lymphoid organ development GO:0048534 191 0.027
regulation of protein localization to nucleus GO:1900180 2 0.027
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.026
negative regulation of protein phosphorylation GO:0001933 4 0.026
locomotion GO:0040011 313 0.026
Worm
endosome to lysosome transport GO:0008333 1 0.026
positive regulation of response to stimulus GO:0048584 80 0.026
cellular macromolecular complex assembly GO:0034622 24 0.026
negative regulation of i kappab kinase nf kappab signaling GO:0043124 1 0.025
regulation of protein localization to plasma membrane GO:1903076 1 0.025
membrane fusion GO:0061025 2 0.025
gtp catabolic process GO:0006184 2 0.025
carbohydrate derivative metabolic process GO:1901135 61 0.025
regulation of cellular component organization GO:0051128 86 0.025
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.025
endosome organization GO:0007032 2 0.025
positive regulation of immune effector process GO:0002699 3 0.025
positive regulation of secretion by cell GO:1903532 1 0.025
Worm
regulation of response to stress GO:0080134 36 0.024
small molecule metabolic process GO:0044281 77 0.024
negative regulation of multicellular organismal process GO:0051241 69 0.024
regulation of reactive oxygen species metabolic process GO:2000377 2 0.024
cellular response to molecule of bacterial origin GO:0071219 3 0.024
response to monosaccharide GO:0034284 3 0.024
aromatic compound biosynthetic process GO:0019438 217 0.024
response to nutrient levels GO:0031667 10 0.023
organelle fusion GO:0048284 3 0.023
negative regulation of intracellular protein transport GO:0090317 3 0.023
regulation of transport GO:0051049 45 0.023
Worm
leukocyte differentiation GO:0002521 25 0.023
protein metabolic process GO:0019538 183 0.023
cellular macromolecule biosynthetic process GO:0034645 224 0.023
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.023
b cell mediated immunity GO:0019724 3 0.023
nucleic acid templated transcription GO:0097659 181 0.023
lymphocyte proliferation GO:0046651 1 0.023
cellular amine metabolic process GO:0044106 2 0.023
positive regulation of signal transduction GO:0009967 56 0.023
cellular response to biotic stimulus GO:0071216 3 0.023
response to drug GO:0042493 3 0.022
autophagy GO:0006914 4 0.022
negative regulation of sequestering of calcium ion GO:0051283 4 0.022
organic cyclic compound biosynthetic process GO:1901362 223 0.022
actin filament polymerization GO:0030041 2 0.022
muscle structure development GO:0061061 196 0.022
organic acid metabolic process GO:0006082 31 0.022
response to alkaloid GO:0043279 2 0.022
transcription dna templated GO:0006351 181 0.022
cation homeostasis GO:0055080 33 0.022
positive regulation of cell communication GO:0010647 56 0.022
Worm
germ cell development GO:0007281 22 0.021
Fly
regulation of synapse organization GO:0050807 3 0.021
axonogenesis GO:0007409 152 0.021
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.021
Fly
vacuole organization GO:0007033 9 0.021
regulation of multicellular organismal development GO:2000026 223 0.021
Fly
response to stress GO:0006950 263 0.021
regulation of binding GO:0051098 3 0.021
regulation of calcium ion transport GO:0051924 2 0.021
gamete generation GO:0007276 33 0.021
Fly
response to extracellular stimulus GO:0009991 10 0.020
rna biosynthetic process GO:0032774 181 0.020
regulation of intracellular signal transduction GO:1902531 57 0.020
melanosome organization GO:0032438 4 0.020
cellular lipid catabolic process GO:0044242 3 0.020
regulation of anatomical structure size GO:0090066 33 0.020
programmed cell death GO:0012501 119 0.020
negative regulation of cytokine production GO:0001818 1 0.020
regulation of metal ion transport GO:0010959 4 0.020
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.020
cellular protein modification process GO:0006464 100 0.020
endocytosis GO:0006897 16 0.020
positive regulation of cellular amine metabolic process GO:0033240 0 0.019
cell activation GO:0001775 16 0.019
Human
cellular macromolecule localization GO:0070727 21 0.019
Fly
meiotic cell cycle process GO:1903046 3 0.019
regulation of rna biosynthetic process GO:2001141 213 0.019
transcription from rna polymerase ii promoter GO:0006366 80 0.019
lytic vacuole organization GO:0080171 1 0.019
regulation of cellular ketone metabolic process GO:0010565 7 0.019
cellular response to stress GO:0033554 62 0.019
peptidyl serine modification GO:0018209 2 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.018
cellular ketone metabolic process GO:0042180 11 0.018
regulation of ion transmembrane transporter activity GO:0032412 2 0.018
protein localization GO:0008104 40 0.018
extrinsic apoptotic signaling pathway GO:0097191 3 0.018
regulation of response to cytokine stimulus GO:0060759 3 0.018
negative regulation of macromolecule metabolic process GO:0010605 76 0.018
interaction with host GO:0051701 4 0.018
regulation of nucleoside metabolic process GO:0009118 2 0.018
phagocytosis GO:0006909 3 0.018
positive regulation of stress activated mapk cascade GO:0032874 3 0.018
positive regulation of metabolic process GO:0009893 108 0.017
glycoprotein metabolic process GO:0009100 23 0.017
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.017
multi organism reproductive process GO:0044703 36 0.017
Fly
cellular protein localization GO:0034613 20 0.017
regulation of protein polymerization GO:0032271 2 0.017
defense response GO:0006952 47 0.017
vesicle mediated transport GO:0016192 22 0.017
Human Worm
regulation of response to biotic stimulus GO:0002831 2 0.017
protein phosphorylation GO:0006468 47 0.017
response to bacterium GO:0009617 58 0.017
signal transduction in absence of ligand GO:0038034 1 0.016
multicellular organismal signaling GO:0035637 22 0.016
generation of neurons GO:0048699 385 0.016
cellular component biogenesis GO:0044085 178 0.016
Fly
response to chemical GO:0042221 320 0.016
regulation of muscle contraction GO:0006937 3 0.016
leukocyte activation GO:0045321 12 0.016
Human
rho protein signal transduction GO:0007266 5 0.016
interspecies interaction between organisms GO:0044419 4 0.016
gtp metabolic process GO:0046039 4 0.016
positive regulation of signaling GO:0023056 56 0.016
Worm
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.016
leukocyte proliferation GO:0070661 1 0.016
cytoplasmic transport GO:0016482 11 0.016
iron ion homeostasis GO:0055072 4 0.016
lysosomal transport GO:0007041 2 0.016
regulation of organ growth GO:0046620 3 0.016
protein localization to plasma membrane GO:0072659 1 0.016
sequestering of metal ion GO:0051238 3 0.016
nucleic acid metabolic process GO:0090304 244 0.015
immunoglobulin mediated immune response GO:0016064 3 0.015
cellular response to organic substance GO:0071310 105 0.015
regulation of nucleotide catabolic process GO:0030811 2 0.015
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.015
regulation of gtpase activity GO:0043087 2 0.015
regulation of hormone secretion GO:0046883 2 0.015
response to endogenous stimulus GO:0009719 83 0.015
regulation of signal transduction GO:0009966 225 0.015
vesicle organization GO:0016050 6 0.015
cation transport GO:0006812 81 0.015
dicarboxylic acid metabolic process GO:0043648 1 0.014
negative regulation of developmental process GO:0051093 65 0.014
regulation of cytokine biosynthetic process GO:0042035 1 0.014
organelle fission GO:0048285 23 0.014
regulation of developmental growth GO:0048638 38 0.014
cellular response to oxygen containing compound GO:1901701 20 0.014
positive regulation of biosynthetic process GO:0009891 68 0.014
actin cytoskeleton organization GO:0030036 63 0.014
response to glucose GO:0009749 3 0.014
regulation of cytokine mediated signaling pathway GO:0001959 3 0.014
calcium ion transport into cytosol GO:0060402 3 0.014
protein complex biogenesis GO:0070271 30 0.014
regulation of rna metabolic process GO:0051252 224 0.014
macromolecular complex assembly GO:0065003 35 0.014
positive regulation of cytoskeleton organization GO:0051495 3 0.014
establishment of localization in cell GO:0051649 77 0.014
Human Worm Fly
response to other organism GO:0051707 97 0.014
vacuolar transport GO:0007034 2 0.014
response to external biotic stimulus GO:0043207 97 0.013
response to oxygen containing compound GO:1901700 55 0.013
cell proliferation GO:0008283 80 0.013
myeloid cell homeostasis GO:0002262 56 0.013
establishment or maintenance of cell polarity GO:0007163 29 0.013
stem cell fate commitment GO:0048865 1 0.013
sequestering of calcium ion GO:0051208 3 0.013
positive regulation of rna metabolic process GO:0051254 59 0.013
regulation of protein metabolic process GO:0051246 56 0.013
myotube differentiation GO:0014902 45 0.013
negative regulation of response to cytokine stimulus GO:0060761 2 0.013
response to carbohydrate GO:0009743 3 0.013
response to hexose GO:0009746 3 0.013
regulation of locomotion GO:0040012 55 0.013
localization of cell GO:0051674 244 0.013
proteasomal protein catabolic process GO:0010498 2 0.013
cell migration GO:0016477 237 0.013
cell death GO:0008219 121 0.013
multicellular organismal reproductive process GO:0048609 35 0.013
Fly
striated muscle cell differentiation GO:0051146 129 0.013
macromolecule localization GO:0033036 54 0.013
Fly
cell cell signaling GO:0007267 52 0.013
Worm Fly
positive regulation of defense response to virus by host GO:0002230 0 0.013
chemical homeostasis GO:0048878 49 0.013
regulation of nucleic acid templated transcription GO:1903506 213 0.012
homeostasis of number of cells GO:0048872 62 0.012
circulatory system process GO:0003013 87 0.012
cellular protein metabolic process GO:0044267 129 0.012
hormone transport GO:0009914 2 0.012
negative regulation of defense response GO:0031348 2 0.012
positive regulation of cellular biosynthetic process GO:0031328 68 0.012
muscle cell development GO:0055001 115 0.012
reproduction GO:0000003 40 0.012
Worm Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.012
response to molecule of bacterial origin GO:0002237 14 0.012
single organism intracellular transport GO:1902582 25 0.012
regulation of synapse assembly GO:0051963 3 0.012
positive regulation of jnk cascade GO:0046330 3 0.012
positive regulation of gene expression GO:0010628 71 0.012
metal ion homeostasis GO:0055065 26 0.012
zymogen activation GO:0031638 3 0.012
reactive oxygen species metabolic process GO:0072593 6 0.012
growth GO:0040007 174 0.012
cation transmembrane transport GO:0098655 65 0.012
nucleobase containing small molecule metabolic process GO:0055086 32 0.011
regulation of wound healing GO:0061041 2 0.011
negative regulation of signaling GO:0023057 96 0.011
cellular localization GO:0051641 97 0.011
Human Worm Fly
wound healing GO:0042060 90 0.011
regulation of defense response to virus by host GO:0050691 1 0.011
intracellular transport GO:0046907 32 0.011
regulation of protein catabolic process GO:0042176 1 0.011
inorganic ion transmembrane transport GO:0098660 57 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
regulation of phosphate metabolic process GO:0019220 43 0.011
negative regulation of cytoplasmic transport GO:1903650 2 0.011
regulation of programmed cell death GO:0043067 101 0.011
cellular component assembly involved in morphogenesis GO:0010927 107 0.011
negative regulation of transcription dna templated GO:0045892 45 0.011
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.011
negative regulation of protein transport GO:0051224 3 0.011
protein complex assembly GO:0006461 30 0.011
i kappab phosphorylation GO:0007252 1 0.011
cellular response to xenobiotic stimulus GO:0071466 35 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
negative regulation of multi organism process GO:0043901 3 0.011
ion transport GO:0006811 114 0.011
response to xenobiotic stimulus GO:0009410 45 0.010
nucleoside phosphate biosynthetic process GO:1901293 21 0.010
microtubule based process GO:0007017 60 0.010
muscle fiber development GO:0048747 52 0.010
response to organic substance GO:0010033 153 0.010
phosphorus metabolic process GO:0006793 109 0.010
nuclear division GO:0000280 23 0.010
negative regulation of cell differentiation GO:0045596 46 0.010
glycoprotein biosynthetic process GO:0009101 21 0.010
response to nicotine GO:0035094 2 0.010
regulation of sequestering of calcium ion GO:0051282 4 0.010
regulation of response to extracellular stimulus GO:0032104 1 0.010

stxbp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.066
Human
nervous system disease DOID:863 0 0.019
disease of metabolism DOID:0014667 0 0.015
amyloidosis DOID:9120 0 0.015
acquired metabolic disease DOID:0060158 0 0.015
inherited metabolic disorder DOID:655 0 0.011