Danio rerio

0 known processes

suv39h1b

suppressor of variegation 3-9 homolog 1b

(Aliases: wu:fb18a10,fe47h06,wu:fe47h06,zgc:136593)

suv39h1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
histone methylation GO:0016571 13 0.854
Human Zebrafish Mouse
cellular macromolecule metabolic process GO:0044260 391 0.848
Human Zebrafish Mouse
chromosome organization GO:0051276 31 0.841
Human Zebrafish Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.764
Human Mouse
nitrogen compound metabolic process GO:0006807 319 0.756
Human Mouse
histone lysine methylation GO:0034968 12 0.706
Human Zebrafish Mouse
regulation of primary metabolic process GO:0080090 311 0.620
Human Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.587
Human Mouse
larval development GO:0002164 2 0.506
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.498
Human Mouse
histone h3 k9 methylation GO:0051567 5 0.493
Human Zebrafish Mouse
cellular biosynthetic process GO:0044249 286 0.482
Human Mouse
regulation of cellular metabolic process GO:0031323 320 0.472
Human Mouse
regulation of transcription dna templated GO:0006355 213 0.465
Human Mouse
organic cyclic compound metabolic process GO:1901360 301 0.455
Human Mouse
protein metabolic process GO:0019538 183 0.448
Human Zebrafish Mouse
nucleic acid metabolic process GO:0090304 244 0.436
Human Mouse
histone h3 k9 modification GO:0061647 5 0.400
Human Zebrafish Mouse
heterocycle metabolic process GO:0046483 290 0.395
Human Mouse
chromatin modification GO:0016568 21 0.376
Human Zebrafish Mouse
regulation of nitrogen compound metabolic process GO:0051171 251 0.374
Human Mouse
regulation of metabolic process GO:0019222 359 0.357
Human Mouse
organic substance biosynthetic process GO:1901576 289 0.342
Human Mouse
positive regulation of cellular process GO:0048522 201 0.336
gene expression GO:0010467 252 0.332
Human Mouse
histone h3 k4 methylation GO:0051568 2 0.313
dna methylation or demethylation GO:0044728 8 0.303
organelle organization GO:0006996 227 0.289
Human Zebrafish Mouse
negative regulation of nuclear division GO:0051784 3 0.282
histone h3 k36 methylation GO:0010452 2 0.277
histone h4 k20 methylation GO:0034770 2 0.267
protein alkylation GO:0008213 13 0.255
Human Zebrafish Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.254
Human Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.251
Human Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.245
Human Mouse
ubiquitin dependent protein catabolic process GO:0006511 3 0.240
protein methylation GO:0006479 13 0.234
Human Zebrafish Mouse
biosynthetic process GO:0009058 294 0.223
Human Mouse
nucleobase containing compound biosynthetic process GO:0034654 205 0.214
Human Mouse
macromolecule biosynthetic process GO:0009059 227 0.211
Human Mouse
single organism metabolic process GO:0044710 217 0.201
Human Zebrafish Mouse
histone modification GO:0016570 20 0.198
Human Zebrafish Mouse
double strand break repair GO:0006302 3 0.198
macromolecule modification GO:0043412 111 0.188
Human Zebrafish Mouse
negative regulation of biological process GO:0048519 304 0.187
Human Mouse
cellular protein metabolic process GO:0044267 129 0.179
Human Zebrafish Mouse
single organism organelle organization GO:1902589 199 0.177
Human Zebrafish Mouse
regulation of rna metabolic process GO:0051252 224 0.175
Human Mouse
regulation of rna biosynthetic process GO:2001141 213 0.171
Human Mouse
macromolecule methylation GO:0043414 19 0.166
Human Zebrafish Mouse
covalent chromatin modification GO:0016569 20 0.162
Human Zebrafish Mouse
g2 m transition of mitotic cell cycle GO:0000086 4 0.160
mitotic dna integrity checkpoint GO:0044774 4 0.158
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.155
dna metabolic process GO:0006259 27 0.152
modification dependent protein catabolic process GO:0019941 3 0.151
negative regulation of cellular biosynthetic process GO:0031327 55 0.146
Human Mouse
methylation GO:0032259 22 0.145
Human Zebrafish Mouse
dna modification GO:0006304 8 0.145
regulation of biosynthetic process GO:0009889 250 0.144
Human Mouse
modification dependent macromolecule catabolic process GO:0043632 3 0.141
cellular nitrogen compound biosynthetic process GO:0044271 218 0.139
Human Mouse
regulation of gene expression GO:0010468 265 0.138
Human Mouse
rna biosynthetic process GO:0032774 181 0.131
Human Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.130
Human Mouse
dna methylation GO:0006306 8 0.125
positive regulation of cellular catabolic process GO:0031331 3 0.124
positive regulation of cell cycle GO:0045787 3 0.123
rna metabolic process GO:0016070 219 0.123
Human Mouse
regulation of macromolecule biosynthetic process GO:0010556 225 0.121
Human Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.111
Human Mouse
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.109
cellular macromolecule biosynthetic process GO:0034645 224 0.104
Human Mouse
regulation of response to stimulus GO:0048583 269 0.104
macromolecular complex subunit organization GO:0043933 74 0.104
Human Zebrafish Mouse
gtp metabolic process GO:0046039 4 0.102
centrosome organization GO:0051297 1 0.102
protein modification process GO:0036211 100 0.100
Human Zebrafish Mouse
nucleic acid templated transcription GO:0097659 181 0.100
Human Mouse
peptidyl lysine methylation GO:0018022 3 0.098
Human Mouse
signal transduction GO:0007165 455 0.094
positive regulation of biological process GO:0048518 253 0.093
regulation of multicellular organismal process GO:0051239 277 0.092
positive regulation of metabolic process GO:0009893 108 0.090
digestive system development GO:0055123 289 0.089
Zebrafish
muscle organ development GO:0007517 101 0.087
regulation of protein ubiquitination GO:0031396 3 0.085
cellular component morphogenesis GO:0032989 336 0.084
guanosine containing compound catabolic process GO:1901069 2 0.083
cellular protein catabolic process GO:0044257 4 0.081
small molecule metabolic process GO:0044281 77 0.081
negative regulation of cellular process GO:0048523 283 0.078
Human Mouse
chromosome segregation GO:0007059 12 0.074
negative regulation of biosynthetic process GO:0009890 55 0.072
Human Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.072
Human Mouse
organic substance catabolic process GO:1901575 28 0.070
death GO:0016265 121 0.070
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.067
cellular protein modification process GO:0006464 100 0.065
Human Zebrafish Mouse
negative regulation of macromolecule metabolic process GO:0010605 76 0.064
Human Mouse
regulation of mitotic cell cycle GO:0007346 25 0.063
mitotic cell cycle GO:0000278 64 0.062
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.062
Human
chromatin organization GO:0006325 22 0.061
Human Zebrafish Mouse
guanosine containing compound metabolic process GO:1901068 4 0.061
cytokinesis GO:0000910 3 0.060
organic cyclic compound biosynthetic process GO:1901362 223 0.058
Human Mouse
sister chromatid segregation GO:0000819 6 0.057
regulation of apoptotic process GO:0042981 98 0.057
negative regulation of mitosis GO:0045839 3 0.056
g1 s transition of mitotic cell cycle GO:0000082 1 0.056
aging GO:0007568 2 0.054
mitotic sister chromatid segregation GO:0000070 6 0.052
regulation of signal transduction GO:0009966 225 0.051
embryonic organ development GO:0048568 381 0.051
negative regulation of cell cycle GO:0045786 14 0.050
negative regulation of gene expression GO:0010629 65 0.050
Human Mouse
meiotic nuclear division GO:0007126 4 0.047
nucleic acid transport GO:0050657 2 0.047
cell cycle g2 m phase transition GO:0044839 4 0.046
tube morphogenesis GO:0035239 349 0.046
positive regulation of dna metabolic process GO:0051054 1 0.045
regulation of meiotic cell cycle GO:0051445 1 0.044
negative regulation of chromosome organization GO:2001251 1 0.043
gtp catabolic process GO:0006184 2 0.043
cell cycle g1 s phase transition GO:0044843 1 0.043
regulation of histone methylation GO:0031060 3 0.043
mitotic cell cycle process GO:1903047 48 0.043
regulation of chromosome segregation GO:0051983 1 0.043
sensory organ development GO:0007423 393 0.042
Zebrafish
regulation of protein catabolic process GO:0042176 1 0.042
aromatic compound biosynthetic process GO:0019438 217 0.042
Human Mouse
positive regulation of cellular metabolic process GO:0031325 94 0.041
positive regulation of catabolic process GO:0009896 4 0.041
catabolic process GO:0009056 32 0.041
meiotic chromosome segregation GO:0045132 3 0.039
dna alkylation GO:0006305 8 0.039
cellular catabolic process GO:0044248 27 0.039
nucleoside phosphate metabolic process GO:0006753 28 0.039
transcription dna templated GO:0006351 181 0.039
Human Mouse
heterocycle biosynthetic process GO:0018130 215 0.039
Human Mouse
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.039
cell cycle process GO:0022402 53 0.039
positive regulation of macromolecule metabolic process GO:0010604 93 0.038
response to organic substance GO:0010033 153 0.038
Rat
organonitrogen compound metabolic process GO:1901564 74 0.037
negative regulation of transcription dna templated GO:0045892 45 0.037
Human Mouse
carboxylic acid metabolic process GO:0019752 22 0.036
negative regulation of nucleic acid templated transcription GO:1903507 45 0.035
Human Mouse
regulation of binding GO:0051098 3 0.035
response to oxygen containing compound GO:1901700 55 0.035
regulation of programmed cell death GO:0043067 101 0.035
rna localization GO:0006403 4 0.035
regulation of signaling GO:0023051 235 0.035
cellular amino acid metabolic process GO:0006520 7 0.034
digestive tract development GO:0048565 265 0.034
regulation of cell communication GO:0010646 232 0.034
cellular component biogenesis GO:0044085 178 0.033
regulation of nucleic acid templated transcription GO:1903506 213 0.033
Human Mouse
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.033
maintenance of location GO:0051235 4 0.033
heart development GO:0007507 313 0.033
striated muscle cell differentiation GO:0051146 129 0.033
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.033
Human Mouse
cellular response to chemical stimulus GO:0070887 157 0.033
Human
regulation of purine nucleotide catabolic process GO:0033121 2 0.032
cell projection organization GO:0030030 284 0.032
centrosome cycle GO:0007098 1 0.032
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.032
spindle assembly involved in meiosis GO:0090306 1 0.031
nuclear migration GO:0007097 3 0.031
regulation of multicellular organismal development GO:2000026 223 0.030
microtubule organizing center organization GO:0031023 1 0.030
muscle structure development GO:0061061 196 0.030
regulation of mitotic cell cycle phase transition GO:1901990 8 0.030
carbohydrate derivative metabolic process GO:1901135 61 0.029
phosphate containing compound metabolic process GO:0006796 108 0.029
positive regulation of chromosome segregation GO:0051984 1 0.028
oocyte maturation GO:0001556 4 0.028
meiotic cell cycle process GO:1903046 3 0.028
response to external stimulus GO:0009605 264 0.027
gene silencing GO:0016458 4 0.027
Human
peptidyl threonine phosphorylation GO:0018107 1 0.027
response to drug GO:0042493 3 0.027
regulation of organelle organization GO:0033043 29 0.027
establishment of rna localization GO:0051236 3 0.026
cellular response to oxygen containing compound GO:1901701 20 0.026
response to glucocorticoid GO:0051384 1 0.026
negative regulation of cell cycle process GO:0010948 9 0.026
cellular amine metabolic process GO:0044106 2 0.026
regulation of nucleoside metabolic process GO:0009118 2 0.025
cell cycle GO:0007049 93 0.025
apoptotic process GO:0006915 116 0.025
cell death GO:0008219 121 0.025
negative regulation of cell communication GO:0010648 96 0.025
regulation of dna metabolic process GO:0051052 11 0.024
response to corticosteroid GO:0031960 1 0.024
nucleobase containing small molecule metabolic process GO:0055086 32 0.024
pronuclear migration GO:0035046 1 0.024
response to organic cyclic compound GO:0014070 51 0.024
negative regulation of cellular metabolic process GO:0031324 77 0.024
Human Mouse
mitotic nuclear division GO:0007067 18 0.024
programmed cell death GO:0012501 119 0.024
phosphorus metabolic process GO:0006793 109 0.024
regulation of cellular ketone metabolic process GO:0010565 7 0.023
negative regulation of rna biosynthetic process GO:1902679 45 0.023
Human Mouse
negative regulation of metabolic process GO:0009892 86 0.023
Human Mouse
regulation of histone h3 k9 methylation GO:0051570 2 0.023
regulation of dna recombination GO:0000018 2 0.023
fertilization GO:0009566 3 0.022
regulation of developmental process GO:0050793 247 0.022
response to chemical GO:0042221 320 0.022
Human Rat
regulation of cellular protein metabolic process GO:0032268 52 0.022
mitotic cell cycle embryonic GO:0045448 2 0.022
regulation of cell cycle process GO:0010564 20 0.022
regulation of dna replication GO:0006275 3 0.022
organelle fission GO:0048285 23 0.022
chordate embryonic development GO:0043009 271 0.021
positive regulation of nucleoside metabolic process GO:0045979 1 0.021
cell division GO:0051301 20 0.021
single fertilization GO:0007338 3 0.021
positive regulation of chromatin modification GO:1903310 1 0.021
oxidation reduction process GO:0055114 41 0.021
pancreas development GO:0031016 84 0.021
Zebrafish
embryo development ending in birth or egg hatching GO:0009792 271 0.021
peptidyl serine phosphorylation GO:0018105 1 0.021
negative regulation of rna metabolic process GO:0051253 48 0.021
Human Mouse
generation of neurons GO:0048699 385 0.020
multi organism process GO:0051704 134 0.020
g2 dna damage checkpoint GO:0031572 3 0.020
amine metabolic process GO:0009308 2 0.020
transcription from rna polymerase ii promoter GO:0006366 80 0.020
Human
regulation of proteolysis GO:0030162 24 0.020
regulation of cellular component organization GO:0051128 86 0.020
immunoglobulin mediated immune response GO:0016064 3 0.020
mitotic dna damage checkpoint GO:0044773 4 0.020
mrna transport GO:0051028 2 0.020
proteolysis GO:0006508 38 0.020
response to alkaloid GO:0043279 2 0.020
regulation of cellular protein catabolic process GO:1903362 1 0.020
cellular ketone metabolic process GO:0042180 11 0.020
positive regulation of cell division GO:0051781 2 0.020
cell cycle phase transition GO:0044770 9 0.020
connective tissue development GO:0061448 99 0.020
regulation of intracellular protein transport GO:0033157 3 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
retina development in camera type eye GO:0060041 146 0.019
Zebrafish
positive regulation of leukocyte mediated immunity GO:0002705 1 0.019
organophosphate metabolic process GO:0019637 37 0.019
negative regulation of signal transduction GO:0009968 94 0.019
establishment of localization GO:0051234 244 0.019
vasculature development GO:0001944 278 0.019
proteasomal protein catabolic process GO:0010498 2 0.019
regulation of protein metabolic process GO:0051246 56 0.019
positive regulation of hydrolase activity GO:0051345 13 0.019
regulation of molecular function GO:0065009 70 0.019
dna repair GO:0006281 6 0.018
positive regulation of nucleotide catabolic process GO:0030813 1 0.018
peptidyl lysine dimethylation GO:0018027 1 0.018
Mouse
positive regulation of immune effector process GO:0002699 3 0.018
energy reserve metabolic process GO:0006112 2 0.018
negative regulation of protein phosphorylation GO:0001933 4 0.017
cardiac atrium morphogenesis GO:0003209 2 0.017
positive regulation of transport GO:0051050 2 0.017
double strand break repair via homologous recombination GO:0000724 1 0.017
regulation of chromosome organization GO:0033044 5 0.017
determination of left right symmetry GO:0007368 179 0.017
nucleotide metabolic process GO:0009117 28 0.017
blood vessel development GO:0001568 246 0.017
rna transport GO:0050658 2 0.017
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.016
Human
regulation of reproductive process GO:2000241 4 0.016
heart morphogenesis GO:0003007 156 0.016
positive regulation of histone modification GO:0031058 1 0.016
regulation of cell death GO:0010941 103 0.016
positive regulation of response to stimulus GO:0048584 80 0.016
cell morphogenesis GO:0000902 289 0.016
cell substrate adhesion GO:0031589 4 0.016
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.016
nuclear division GO:0000280 23 0.016
cellular response to external stimulus GO:0071496 2 0.016
nucleocytoplasmic transport GO:0006913 4 0.016
negative regulation of developmental process GO:0051093 65 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.015
protein polymerization GO:0051258 4 0.015
regulation of protein transport GO:0051223 3 0.015
centrosome duplication GO:0051298 1 0.015
cell cycle checkpoint GO:0000075 7 0.015
peptidyl serine modification GO:0018209 2 0.015
development of primary female sexual characteristics GO:0046545 4 0.015
regulation of establishment of protein localization GO:0070201 4 0.015
positive regulation of transcription dna templated GO:0045893 57 0.015
stem cell maintenance GO:0019827 4 0.015
cytoskeleton organization GO:0007010 96 0.015
cellular component movement GO:0006928 335 0.015
organic acid metabolic process GO:0006082 31 0.015
cell part morphogenesis GO:0032990 246 0.015
positive regulation of gene expression GO:0010628 71 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.015
Human Mouse
locomotion GO:0040011 313 0.014
morphogenesis of an epithelium GO:0002009 333 0.014
regulation of gtp catabolic process GO:0033124 2 0.014
regulation of catalytic activity GO:0050790 55 0.014
striated muscle tissue development GO:0014706 110 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
transport GO:0006810 220 0.014
neuron differentiation GO:0030182 353 0.014
gastrulation GO:0007369 208 0.014
intracellular signal transduction GO:0035556 85 0.014
purine ribonucleotide metabolic process GO:0009150 27 0.014
regulation of protein complex assembly GO:0043254 3 0.014
macromolecular complex assembly GO:0065003 35 0.013
regulation of biological quality GO:0065008 263 0.013
oxoacid metabolic process GO:0043436 31 0.013
negative regulation of ras protein signal transduction GO:0046580 1 0.013
regulation of gene expression epigenetic GO:0040029 11 0.013
Human
muscle cell differentiation GO:0042692 139 0.013
meiotic spindle organization GO:0000212 1 0.013
regulation of cell activation GO:0050865 1 0.013
cellular localization GO:0051641 97 0.013
regulation of cytoplasmic transport GO:1903649 4 0.013
reproduction GO:0000003 40 0.013
negative regulation of response to stimulus GO:0048585 104 0.013
regulation of cell cycle GO:0051726 52 0.012
positive regulation of molecular function GO:0044093 33 0.012
regulation of cell differentiation GO:0045595 142 0.012
blood vessel morphogenesis GO:0048514 216 0.012
eye development GO:0001654 277 0.012
Zebrafish
ribose phosphate metabolic process GO:0019693 27 0.012
negative regulation of programmed cell death GO:0043069 58 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
intracellular mrna localization GO:0008298 1 0.012
regulation of chromatin organization GO:1902275 5 0.012
regulation of production of molecular mediator of immune response GO:0002700 1 0.012
establishment of organelle localization GO:0051656 45 0.012
negative regulation of mitotic cell cycle GO:0045930 11 0.012
positive regulation of signaling GO:0023056 56 0.012
regulation of dna methylation GO:0044030 5 0.012
skeletal system development GO:0001501 181 0.012
dicarboxylic acid metabolic process GO:0043648 1 0.012
negative regulation of signaling GO:0023057 96 0.012
negative regulation of cellular catabolic process GO:0031330 3 0.012
cellular component assembly GO:0022607 170 0.012
retina morphogenesis in camera type eye GO:0060042 79 0.012
Zebrafish
response to endogenous stimulus GO:0009719 83 0.012
Rat
neuron projection development GO:0031175 180 0.012
stem cell development GO:0048864 82 0.012
regulation of anatomical structure morphogenesis GO:0022603 130 0.011
recombinational repair GO:0000725 1 0.011
b cell activation GO:0042113 2 0.011
negative regulation of meiotic cell cycle GO:0051447 1 0.011
regulation of hydrolase activity GO:0051336 28 0.011
muscle tissue development GO:0060537 110 0.011
nuclear envelope organization GO:0006998 2 0.011
response to uv GO:0009411 3 0.011
somatic cell dna recombination GO:0016444 1 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.011
male meiosis GO:0007140 2 0.011
protein acetylation GO:0006473 2 0.011
negative regulation of dna metabolic process GO:0051053 4 0.011
central nervous system development GO:0007417 387 0.011
cellular response to stress GO:0033554 62 0.011
Human
chromosome organization involved in meiosis GO:0070192 1 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.011
regulation of cell cycle g2 m phase transition GO:1902749 4 0.011
ameboidal type cell migration GO:0001667 143 0.011
protein polyubiquitination GO:0000209 4 0.011
microtubule based process GO:0007017 60 0.010
phagocytosis GO:0006909 3 0.010
determination of heart left right asymmetry GO:0061371 117 0.010
positive regulation of chromosome organization GO:2001252 1 0.010
purine nucleoside monophosphate catabolic process GO:0009128 4 0.010
cell projection morphogenesis GO:0048858 244 0.010
cellular response to radiation GO:0071478 4 0.010
negative regulation of apoptotic process GO:0043066 55 0.010
establishment of protein localization to organelle GO:0072594 4 0.010
negative regulation of catabolic process GO:0009895 3 0.010
heart looping GO:0001947 94 0.010
positive regulation of protein metabolic process GO:0051247 23 0.010

suv39h1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
physical disorder DOID:0080015 0 0.015
disease of metabolism DOID:0014667 0 0.014
bone disease DOID:0080001 0 0.010
disease of anatomical entity DOID:7 0 0.010
musculoskeletal system disease DOID:17 0 0.010
connective tissue disease DOID:65 0 0.010