Danio rerio

21 known processes

synpo2la

synaptopodin 2-like a

(Aliases: wu:fj80h05)

synpo2la biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryonic organ morphogenesis GO:0048562 274 0.144
endocrine process GO:0050886 2 0.116
muscle tissue development GO:0060537 110 0.099
tube morphogenesis GO:0035239 349 0.085
embryonic organ development GO:0048568 381 0.083
response to external stimulus GO:0009605 264 0.081
heart morphogenesis GO:0003007 156 0.070
signal transduction GO:0007165 455 0.069
regulation of response to stimulus GO:0048583 269 0.069
determination of left right symmetry GO:0007368 179 0.065
regulation of metal ion transport GO:0010959 4 0.064
blood circulation GO:0008015 87 0.058
muscle structure development GO:0061061 196 0.057
embryonic heart tube morphogenesis GO:0003143 108 0.054
chordate embryonic development GO:0043009 271 0.053
determination of heart left right asymmetry GO:0061371 117 0.052
central nervous system development GO:0007417 387 0.051
gene expression GO:0010467 252 0.051
lipid storage GO:0019915 1 0.049
cell motility GO:0048870 244 0.048
digestive tract development GO:0048565 265 0.047
extrinsic apoptotic signaling pathway GO:0097191 3 0.047
aging GO:0007568 2 0.046
regulation of macromolecule metabolic process GO:0060255 317 0.045
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.045
transmembrane transport GO:0055085 120 0.045
cell surface receptor signaling pathway GO:0007166 325 0.043
gland development GO:0048732 143 0.043
cellular component movement GO:0006928 335 0.043
negative regulation of cellular process GO:0048523 283 0.042
heart looping GO:0001947 94 0.041
response to alkaloid GO:0043279 2 0.041
epithelial tube morphogenesis GO:0060562 148 0.039
biosynthetic process GO:0009058 294 0.038
determination of bilateral symmetry GO:0009855 204 0.037
amine metabolic process GO:0009308 2 0.037
regulation of production of molecular mediator of immune response GO:0002700 1 0.036
regulation of cellular amine metabolic process GO:0033238 0 0.035
maintenance of location GO:0051235 4 0.035
tissue remodeling GO:0048771 4 0.034
lipid catabolic process GO:0016042 4 0.034
cell migration GO:0016477 237 0.034
heterocycle biosynthetic process GO:0018130 215 0.034
neuron development GO:0048666 262 0.033
cellular biosynthetic process GO:0044249 286 0.033
regulation of primary metabolic process GO:0080090 311 0.033
gastrulation GO:0007369 208 0.033
vasculature development GO:0001944 278 0.033
regulation of signal transduction GO:0009966 225 0.032
cellular response to external stimulus GO:0071496 2 0.032
regulation of cytokine production GO:0001817 3 0.031
morphogenesis of an epithelium GO:0002009 333 0.031
response to nutrient GO:0007584 3 0.031
organic cyclic compound biosynthetic process GO:1901362 223 0.031
nitrogen compound metabolic process GO:0006807 319 0.031
regulation of cellular biosynthetic process GO:0031326 245 0.031
positive regulation of biological process GO:0048518 253 0.030
regulation of multicellular organismal process GO:0051239 277 0.030
heart development GO:0007507 313 0.029
cellular component morphogenesis GO:0032989 336 0.029
regulation of reproductive process GO:2000241 4 0.029
regulation of blood pressure GO:0008217 1 0.028
cellular protein catabolic process GO:0044257 4 0.028
stem cell proliferation GO:0072089 4 0.028
nucleobase containing compound biosynthetic process GO:0034654 205 0.027
regulation of cellular amino acid metabolic process GO:0006521 0 0.027
positive regulation of cytokine production GO:0001819 2 0.027
regulation of biosynthetic process GO:0009889 250 0.027
ion transmembrane transport GO:0034220 91 0.027
nucleic acid metabolic process GO:0090304 244 0.027
organic substance biosynthetic process GO:1901576 289 0.027
regulation of gene expression GO:0010468 265 0.027
single organism metabolic process GO:0044710 217 0.027
nucleobase containing compound metabolic process GO:0006139 274 0.027
g protein coupled receptor signaling pathway GO:0007186 74 0.027
ion transport GO:0006811 114 0.027
brain development GO:0007420 293 0.026
digestive tract morphogenesis GO:0048546 231 0.026
cellular amine metabolic process GO:0044106 2 0.026
cell projection morphogenesis GO:0048858 244 0.026
response to organic substance GO:0010033 153 0.025
eye development GO:0001654 277 0.025
rna biosynthetic process GO:0032774 181 0.025
negative regulation of response to stimulus GO:0048585 104 0.025
regulation of nitrogen compound metabolic process GO:0051171 251 0.024
inorganic cation transmembrane transport GO:0098662 50 0.024
regulation of calcium ion transport GO:0051924 2 0.024
cell part morphogenesis GO:0032990 246 0.024
adult behavior GO:0030534 2 0.024
protein import GO:0017038 3 0.024
system process GO:0003008 185 0.023
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.023
cellular macromolecule metabolic process GO:0044260 391 0.023
mononuclear cell proliferation GO:0032943 1 0.023
regulation of cell communication GO:0010646 232 0.023
negative regulation of biological process GO:0048519 304 0.023
phagocytosis GO:0006909 3 0.023
liver development GO:0001889 96 0.023
regulation of transmembrane transport GO:0034762 18 0.023
nucleic acid templated transcription GO:0097659 181 0.022
cell morphogenesis GO:0000902 289 0.022
production of molecular mediator of immune response GO:0002440 2 0.022
regulation of cell activation GO:0050865 1 0.022
dicarboxylic acid transport GO:0006835 1 0.022
organic cyclic compound metabolic process GO:1901360 301 0.022
regulation of multicellular organism growth GO:0040014 4 0.022
regulation of developmental process GO:0050793 247 0.022
cation transport GO:0006812 81 0.022
regulation of protein catabolic process GO:0042176 1 0.022
inorganic ion transmembrane transport GO:0098660 57 0.021
cellular component assembly involved in morphogenesis GO:0010927 107 0.021
regulation of synaptic plasticity GO:0048167 1 0.021
cellular response to nutrient levels GO:0031669 2 0.021
protein localization to nucleus GO:0034504 3 0.021
multicellular organism growth GO:0035264 4 0.021
lateral inhibition GO:0046331 1 0.021
nuclear transport GO:0051169 4 0.021
positive regulation of immune effector process GO:0002699 3 0.021
sensory organ development GO:0007423 393 0.021
heterocycle metabolic process GO:0046483 290 0.021
cellular amide metabolic process GO:0043603 4 0.021
skeletal muscle tissue development GO:0007519 67 0.021
sensory perception of chemical stimulus GO:0007606 3 0.021
hepaticobiliary system development GO:0061008 98 0.020
regulation of systemic arterial blood pressure GO:0003073 1 0.020
response to glucose GO:0009749 3 0.020
negative regulation of secretion by cell GO:1903531 2 0.020
regulation of apoptotic process GO:0042981 98 0.020
immune system process GO:0002376 241 0.020
regulation of blood vessel size GO:0050880 2 0.020
negative regulation of metabolic process GO:0009892 86 0.020
cellular response to extracellular stimulus GO:0031668 2 0.020
regulation of signaling GO:0023051 235 0.020
transcription dna templated GO:0006351 181 0.020
regulation of metabolic process GO:0019222 359 0.020
cellular response to organic substance GO:0071310 105 0.020
regulation of cellular ketone metabolic process GO:0010565 7 0.020
metal ion transport GO:0030001 58 0.020
response to carbohydrate GO:0009743 3 0.020
lymphocyte proliferation GO:0046651 1 0.019
rna metabolic process GO:0016070 219 0.019
regulation of stem cell proliferation GO:0072091 2 0.019
hormone secretion GO:0046879 2 0.019
localization of cell GO:0051674 244 0.019
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.019
regulation of cellular metabolic process GO:0031323 320 0.019
protein metabolic process GO:0019538 183 0.019
cellular ketone metabolic process GO:0042180 11 0.019
neuroblast proliferation GO:0007405 2 0.019
small molecule metabolic process GO:0044281 77 0.019
regulation of tube size GO:0035150 2 0.019
cellular nitrogen compound metabolic process GO:0034641 290 0.018
leukocyte proliferation GO:0070661 1 0.018
cation transmembrane transport GO:0098655 65 0.018
protein targeting to nucleus GO:0044744 3 0.018
peptide metabolic process GO:0006518 1 0.018
establishment of protein localization to organelle GO:0072594 4 0.018
response to wounding GO:0009611 116 0.018
peptidyl serine modification GO:0018209 2 0.018
somatic muscle development GO:0007525 4 0.018
cell proliferation GO:0008283 80 0.018
nuclear import GO:0051170 3 0.018
cellular response to starvation GO:0009267 1 0.018
antimicrobial humoral response GO:0019730 2 0.018
sensory organ morphogenesis GO:0090596 200 0.018
positive regulation of cell activation GO:0050867 1 0.018
organonitrogen compound metabolic process GO:1901564 74 0.018
cell matrix adhesion GO:0007160 4 0.018
regulation of establishment of protein localization GO:0070201 4 0.018
neuron projection development GO:0031175 180 0.018
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.018
regulation of cell shape GO:0008360 1 0.017
positive regulation of cellular process GO:0048522 201 0.017
blood vessel morphogenesis GO:0048514 216 0.017
blood vessel development GO:0001568 246 0.017
cell projection organization GO:0030030 284 0.017
response to glucocorticoid GO:0051384 1 0.017
neurological system process GO:0050877 62 0.017
response to corticosteroid GO:0031960 1 0.017
growth GO:0040007 174 0.017
head development GO:0060322 303 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
regulation of programmed cell death GO:0043067 101 0.017
negative regulation of catabolic process GO:0009895 3 0.017
heart contraction GO:0060047 71 0.017
positive regulation of catabolic process GO:0009896 4 0.017
negative regulation of protein phosphorylation GO:0001933 4 0.017
gtp catabolic process GO:0006184 2 0.017
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.017
digestive system development GO:0055123 289 0.017
cellular amino acid metabolic process GO:0006520 7 0.017
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.016
regulation of protein transport GO:0051223 3 0.016
guanosine containing compound catabolic process GO:1901069 2 0.016
regulation of epithelial cell proliferation GO:0050678 3 0.016
positive regulation of leukocyte mediated cytotoxicity GO:0001912 1 0.016
intracellular signal transduction GO:0035556 85 0.016
nucleocytoplasmic transport GO:0006913 4 0.016
carbohydrate homeostasis GO:0033500 1 0.016
b cell activation GO:0042113 2 0.016
ubiquitin dependent protein catabolic process GO:0006511 3 0.016
regulation of transmembrane transporter activity GO:0022898 2 0.016
positive regulation of cellular component biogenesis GO:0044089 3 0.016
retina development in camera type eye GO:0060041 146 0.016
response to chemical GO:0042221 320 0.016
eye morphogenesis GO:0048592 144 0.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.016
positive regulation of transport GO:0051050 2 0.016
regulation of ion transmembrane transporter activity GO:0032412 2 0.016
macromolecule biosynthetic process GO:0009059 227 0.016
gtp metabolic process GO:0046039 4 0.016
glucose homeostasis GO:0042593 1 0.016
regulation of inflammatory response GO:0050727 2 0.015
regulation of biological quality GO:0065008 263 0.015
mitochondrion organization GO:0007005 4 0.015
larval development GO:0002164 2 0.015
peptidyl lysine acetylation GO:0018394 2 0.015
regulation of anatomical structure morphogenesis GO:0022603 130 0.015
autophagy GO:0006914 4 0.015
negative regulation of kinase activity GO:0033673 4 0.015
cellular protein metabolic process GO:0044267 129 0.015
urogenital system development GO:0001655 97 0.015
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.015
behavior GO:0007610 74 0.015
ribonucleotide biosynthetic process GO:0009260 20 0.015
cranial nerve development GO:0021545 42 0.015
internal protein amino acid acetylation GO:0006475 2 0.015
notochord development GO:0030903 54 0.015
negative regulation of protein kinase activity GO:0006469 4 0.015
g1 s transition of mitotic cell cycle GO:0000082 1 0.015
cellular response to chemical stimulus GO:0070887 157 0.015
internal peptidyl lysine acetylation GO:0018393 2 0.015
multi organism process GO:0051704 134 0.015
negative regulation of cell communication GO:0010648 96 0.015
renal system development GO:0072001 94 0.014
inner ear development GO:0048839 126 0.014
modification dependent protein catabolic process GO:0019941 3 0.014
sleep GO:0030431 1 0.014
development of primary female sexual characteristics GO:0046545 4 0.014
positive regulation of chromatin modification GO:1903310 1 0.014
cell substrate adhesion GO:0031589 4 0.014
regulation of purine nucleotide catabolic process GO:0033121 2 0.014
cellular macromolecule biosynthetic process GO:0034645 224 0.014
atp catabolic process GO:0006200 4 0.014
cellular pigmentation GO:0033059 30 0.014
protein import into nucleus GO:0006606 3 0.014
proteasomal protein catabolic process GO:0010498 2 0.014
i kappab kinase nf kappab signaling GO:0007249 4 0.014
hemopoiesis GO:0030097 183 0.014
transport GO:0006810 220 0.014
protein acetylation GO:0006473 2 0.014
negative regulation of mapk cascade GO:0043409 4 0.014
positive regulation of chromosome organization GO:2001252 1 0.014
neuron neuron synaptic transmission GO:0007270 1 0.014
negative regulation of secretion GO:0051048 2 0.014
skeletal muscle organ development GO:0060538 78 0.014
cellular response to biotic stimulus GO:0071216 3 0.014
regulation of macromolecule biosynthetic process GO:0010556 225 0.014
wnt signaling pathway GO:0016055 80 0.014
organic acid metabolic process GO:0006082 31 0.014
somitogenesis GO:0001756 87 0.014
guanosine containing compound metabolic process GO:1901068 4 0.014
negative regulation of dna metabolic process GO:0051053 4 0.014
sensory perception of smell GO:0007608 2 0.013
regionalization GO:0003002 274 0.013
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.013
regulation of protein complex assembly GO:0043254 3 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
sprouting angiogenesis GO:0002040 53 0.013
immune system development GO:0002520 191 0.013
regulation of synapse organization GO:0050807 3 0.013
lipid metabolic process GO:0006629 52 0.013
regulation of endocrine process GO:0044060 2 0.013
response to other organism GO:0051707 97 0.013
protein acylation GO:0043543 3 0.013
positive regulation of multicellular organismal process GO:0051240 52 0.013
negative regulation of cytoplasmic transport GO:1903650 2 0.013
regulation of nucleic acid templated transcription GO:1903506 213 0.013
regeneration GO:0031099 91 0.013
positive regulation of cell killing GO:0031343 2 0.013
regulation of response to external stimulus GO:0032101 31 0.013
regulation of multicellular organismal development GO:2000026 223 0.013
cell cycle g1 s phase transition GO:0044843 1 0.013
regulation of response to biotic stimulus GO:0002831 2 0.013
stem cell maintenance GO:0019827 4 0.013
regulation of system process GO:0044057 40 0.013
regulation of transcription dna templated GO:0006355 213 0.013
interspecies interaction between organisms GO:0044419 4 0.013
regulation of cell projection assembly GO:0060491 4 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.013
phosphate containing compound metabolic process GO:0006796 108 0.013
regulation of neurological system process GO:0031644 2 0.013
generation of neurons GO:0048699 385 0.013
axonal defasciculation GO:0007414 2 0.013
positive regulation of histone modification GO:0031058 1 0.013
cellular aromatic compound metabolic process GO:0006725 295 0.013
neuron differentiation GO:0030182 353 0.012
regulation of transporter activity GO:0032409 2 0.012
muscle organ development GO:0007517 101 0.012
positive regulation of dna metabolic process GO:0051054 1 0.012
striated muscle tissue development GO:0014706 110 0.012
positive regulation of leukocyte differentiation GO:1902107 1 0.012
regulation of cell death GO:0010941 103 0.012
regulation of sodium ion transport GO:0002028 2 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.012
regulation of hormone secretion GO:0046883 2 0.012
negative regulation of gene expression GO:0010629 65 0.012
enzyme linked receptor protein signaling pathway GO:0007167 106 0.012
actin filament based movement GO:0030048 1 0.012
transcription from rna polymerase ii promoter GO:0006366 80 0.012
regulation of neural precursor cell proliferation GO:2000177 3 0.012
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.012
positive regulation of cellular catabolic process GO:0031331 3 0.012
single organism localization GO:1902578 225 0.012
cell death GO:0008219 121 0.012
skeletal system morphogenesis GO:0048705 102 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.012
synaptic vesicle transport GO:0048489 1 0.012
dorsal ventral pattern formation GO:0009953 125 0.012
regulation of cytoplasmic transport GO:1903649 4 0.012
regulation of circadian rhythm GO:0042752 4 0.012
oxoacid metabolic process GO:0043436 31 0.012
kidney development GO:0001822 92 0.012
negative regulation of signaling GO:0023057 96 0.012
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 1 0.012
death GO:0016265 121 0.012
regulation of ion transmembrane transport GO:0034765 18 0.012
response to hexose GO:0009746 3 0.012
locomotion GO:0040011 313 0.012
regulation of protein targeting GO:1903533 2 0.012
embryonic heart tube development GO:0035050 133 0.011
aromatic compound biosynthetic process GO:0019438 217 0.011
regulation of dendrite development GO:0050773 3 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
response to monosaccharide GO:0034284 3 0.011
regulation of autophagy GO:0010506 3 0.011
neurotransmitter secretion GO:0007269 2 0.011
microtubule organizing center organization GO:0031023 1 0.011
calcium ion import GO:0070509 4 0.011
b cell differentiation GO:0030183 1 0.011
response to drug GO:0042493 3 0.011
positive regulation of metabolic process GO:0009893 108 0.011
hormone transport GO:0009914 2 0.011
circulatory system process GO:0003013 87 0.011
compound eye development GO:0048749 2 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
embryo development ending in birth or egg hatching GO:0009792 271 0.011
regulation of reactive oxygen species metabolic process GO:2000377 2 0.011
adherens junction organization GO:0034332 4 0.011
regulation of response to extracellular stimulus GO:0032104 1 0.011
negative regulation of immune response GO:0050777 2 0.011
cellular protein modification process GO:0006464 100 0.011
positive regulation of apoptotic signaling pathway GO:2001235 1 0.011
specification of symmetry GO:0009799 204 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
segmentation GO:0035282 97 0.011
regulation of protein import into nucleus GO:0042306 2 0.011
organelle organization GO:0006996 227 0.011
cellular response to oxygen levels GO:0071453 1 0.011
epithelial cell differentiation GO:0030855 116 0.011
negative regulation of cell death GO:0060548 60 0.011
positive regulation of response to stimulus GO:0048584 80 0.011
positive regulation of leukocyte mediated immunity GO:0002705 1 0.011
ameboidal type cell migration GO:0001667 143 0.011
meiotic nuclear division GO:0007126 4 0.011
positive regulation of multi organism process GO:0043902 3 0.011
negative regulation of cytokine production GO:0001818 1 0.011
canonical wnt signaling pathway GO:0060070 48 0.011
cellular nitrogen compound biosynthetic process GO:0044271 218 0.011
macromolecule modification GO:0043412 111 0.011
regulation of rna metabolic process GO:0051252 224 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
inositol lipid mediated signaling GO:0048017 2 0.011
negative regulation of signal transduction GO:0009968 94 0.011
multicellular organismal response to stress GO:0033555 2 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.011
thermosensory behavior GO:0040040 1 0.011
stem cell division GO:0017145 1 0.011
ear development GO:0043583 127 0.011
tissue migration GO:0090130 37 0.010
endocrine hormone secretion GO:0060986 2 0.010
single organism nuclear import GO:1902593 3 0.010
response to endogenous stimulus GO:0009719 83 0.010
establishment of localization GO:0051234 244 0.010
cognition GO:0050890 1 0.010
centrosome organization GO:0051297 1 0.010
response to stress GO:0006950 263 0.010
protein dephosphorylation GO:0006470 3 0.010
regulation of binding GO:0051098 3 0.010
single organism biosynthetic process GO:0044711 71 0.010
cellular response to hypoxia GO:0071456 1 0.010
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.010
alcohol biosynthetic process GO:0046165 2 0.010
peptide transport GO:0015833 1 0.010
retinal rod cell development GO:0046548 4 0.010
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.010
neurotransmitter transport GO:0006836 2 0.010
embryonic skeletal system development GO:0048706 97 0.010
positive regulation of stem cell proliferation GO:2000648 1 0.010
negative regulation of protein transport GO:0051224 3 0.010
mesenchyme development GO:0060485 127 0.010
synaptic vesicle localization GO:0097479 1 0.010

synpo2la disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.017
cardiovascular system disease DOID:1287 0 0.015
immune system disease DOID:2914 0 0.014
disease of metabolism DOID:0014667 0 0.014