Danio rerio

21 known processes

synpo2lb

synaptopodin 2-like b

(Aliases: im:7159270)

synpo2lb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
heart development GO:0007507 313 0.876
cardiac muscle tissue development GO:0048738 48 0.711
muscle tissue development GO:0060537 110 0.617
embryonic heart tube morphogenesis GO:0003143 108 0.615
striated muscle tissue development GO:0014706 110 0.583
heart morphogenesis GO:0003007 156 0.553
muscle structure development GO:0061061 196 0.543
striated muscle cell differentiation GO:0051146 129 0.459
heart process GO:0003015 71 0.450
determination of bilateral symmetry GO:0009855 204 0.405
embryonic heart tube development GO:0035050 133 0.393
cardiac muscle cell differentiation GO:0055007 30 0.353
determination of heart left right asymmetry GO:0061371 117 0.349
muscle cell differentiation GO:0042692 139 0.336
embryonic organ development GO:0048568 381 0.299
specification of symmetry GO:0009799 204 0.287
regulation of blood circulation GO:1903522 32 0.263
tube morphogenesis GO:0035239 349 0.252
circulatory system process GO:0003013 87 0.249
digestive tract development GO:0048565 265 0.248
morphogenesis of an epithelium GO:0002009 333 0.244
regulation of heart contraction GO:0008016 32 0.233
cardiocyte differentiation GO:0035051 44 0.225
central nervous system development GO:0007417 387 0.200
cellular component movement GO:0006928 335 0.200
heart contraction GO:0060047 71 0.188
transmembrane transport GO:0055085 120 0.179
determination of left right symmetry GO:0007368 179 0.163
heart looping GO:0001947 94 0.156
blood circulation GO:0008015 87 0.153
cardiac muscle cell development GO:0055013 20 0.145
epithelial tube morphogenesis GO:0060562 148 0.140
embryonic organ morphogenesis GO:0048562 274 0.133
locomotion GO:0040011 313 0.128
convergent extension involved in gastrulation GO:0060027 71 0.116
ameboidal type cell migration GO:0001667 143 0.116
positive regulation of transport GO:0051050 2 0.114
cell motility GO:0048870 244 0.111
maintenance of location GO:0051235 4 0.108
lipid storage GO:0019915 1 0.097
single organism transport GO:0044765 206 0.096
regulation of actin filament based movement GO:1903115 1 0.096
divalent inorganic cation homeostasis GO:0072507 22 0.087
nucleobase containing compound metabolic process GO:0006139 274 0.086
regulation of dendrite development GO:0050773 3 0.085
digestive system development GO:0055123 289 0.085
muscle organ development GO:0007517 101 0.079
actin filament based movement GO:0030048 1 0.076
regulation of ion transmembrane transporter activity GO:0032412 2 0.076
cell projection organization GO:0030030 284 0.074
organelle assembly GO:0070925 110 0.073
response to external stimulus GO:0009605 264 0.072
inorganic cation transmembrane transport GO:0098662 50 0.070
regulation of blood pressure GO:0008217 1 0.070
aging GO:0007568 2 0.070
cellular component assembly involved in morphogenesis GO:0010927 107 0.069
spermatid development GO:0007286 2 0.068
positive regulation of heart contraction GO:0045823 2 0.067
skeletal muscle organ development GO:0060538 78 0.067
cellular component assembly GO:0022607 170 0.065
response to nutrient GO:0007584 3 0.064
actin filament based process GO:0030029 64 0.063
stem cell differentiation GO:0048863 117 0.063
regulation of muscle contraction GO:0006937 3 0.063
regulation of striated muscle contraction GO:0006942 2 0.061
cell substrate adhesion GO:0031589 4 0.060
regulation of cellular component organization GO:0051128 86 0.060
calcium ion import GO:0070509 4 0.059
monocyte differentiation GO:0030224 2 0.059
neurotransmitter secretion GO:0007269 2 0.058
localization of cell GO:0051674 244 0.058
negative regulation of heart contraction GO:0045822 2 0.058
response to fluid shear stress GO:0034405 2 0.058
heterocycle metabolic process GO:0046483 290 0.057
cell migration GO:0016477 237 0.057
gastrulation GO:0007369 208 0.056
cardiac muscle cell contraction GO:0086003 1 0.055
ventricular cardiac muscle tissue development GO:0003229 3 0.055
system process GO:0003008 185 0.054
striated muscle contraction GO:0006941 12 0.054
regulation of developmental process GO:0050793 247 0.053
regulation of cardiac muscle cell contraction GO:0086004 1 0.052
brain development GO:0007420 293 0.052
regulation of cardiac muscle tissue development GO:0055024 1 0.050
regulation of cell shape GO:0008360 1 0.050
cellular component maintenance GO:0043954 3 0.050
single organism localization GO:1902578 225 0.049
positive regulation of biological process GO:0048518 253 0.048
cardiac conduction system development GO:0003161 1 0.048
cardiac chamber formation GO:0003207 4 0.048
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.047
cardiac muscle fiber development GO:0048739 3 0.047
developmental growth GO:0048589 166 0.047
organelle organization GO:0006996 227 0.046
neuron differentiation GO:0030182 353 0.045
cardiac cell development GO:0055006 21 0.045
positive regulation of striated muscle tissue development GO:0045844 1 0.045
notochord development GO:0030903 54 0.044
striated muscle cell development GO:0055002 108 0.044
cardiac conduction GO:0061337 3 0.044
inorganic ion transmembrane transport GO:0098660 57 0.044
positive regulation of blood circulation GO:1903524 2 0.042
spermatid differentiation GO:0048515 2 0.042
cytoskeleton organization GO:0007010 96 0.042
ventricular cardiac muscle cell differentiation GO:0055012 6 0.041
convergent extension GO:0060026 118 0.041
sarcomere organization GO:0045214 26 0.041
chordate embryonic development GO:0043009 271 0.041
regulation of organelle assembly GO:1902115 4 0.041
regulation of system process GO:0044057 40 0.041
metal ion transport GO:0030001 58 0.041
regulation of biological quality GO:0065008 263 0.040
regulation of synapse assembly GO:0051963 3 0.039
cellular component biogenesis GO:0044085 178 0.039
larval development GO:0002164 2 0.039
multi organism process GO:0051704 134 0.039
neurotransmitter transport GO:0006836 2 0.038
digestive tract morphogenesis GO:0048546 231 0.038
cation transmembrane transport GO:0098655 65 0.038
establishment of localization GO:0051234 244 0.037
mechanosensory behavior GO:0007638 2 0.037
signal transduction GO:0007165 455 0.036
adult behavior GO:0030534 2 0.035
embryo development ending in birth or egg hatching GO:0009792 271 0.035
regulation of multicellular organismal process GO:0051239 277 0.035
regulation of transmembrane transporter activity GO:0022898 2 0.034
regulation of myotube differentiation GO:0010830 2 0.034
regulation of cardiac muscle cell differentiation GO:2000725 1 0.033
mesenchyme development GO:0060485 127 0.033
cell morphogenesis GO:0000902 289 0.033
cellular component morphogenesis GO:0032989 336 0.033
regulation of cardiac muscle contraction GO:0055117 2 0.033
cell adhesion GO:0007155 40 0.033
rna processing GO:0006396 25 0.033
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.032
regulation of protein binding GO:0043393 3 0.032
positive regulation of muscle tissue development GO:1901863 1 0.031
cardiac atrium morphogenesis GO:0003209 2 0.031
regulation of transporter activity GO:0032409 2 0.031
cellular aromatic compound metabolic process GO:0006725 295 0.031
somatic muscle development GO:0007525 4 0.031
pigment cell development GO:0070285 3 0.031
regulation of skeletal muscle fiber development GO:0048742 2 0.030
heterocycle biosynthetic process GO:0018130 215 0.030
regulation of heart rate GO:0002027 5 0.029
regulation of synapse organization GO:0050807 3 0.029
regulation of anatomical structure morphogenesis GO:0022603 130 0.029
cellular nitrogen compound metabolic process GO:0034641 290 0.029
nitrogen compound metabolic process GO:0006807 319 0.029
positive regulation of cellular component biogenesis GO:0044089 3 0.029
head development GO:0060322 303 0.029
muscle contraction GO:0006936 18 0.029
regulation of heart growth GO:0060420 2 0.028
mesendoderm development GO:0048382 10 0.028
single organism metabolic process GO:0044710 217 0.028
ion homeostasis GO:0050801 41 0.028
organic substance biosynthetic process GO:1901576 289 0.028
skeletal muscle tissue development GO:0007519 67 0.027
nucleic acid metabolic process GO:0090304 244 0.027
regulation of calcium ion transport GO:0051924 2 0.027
cardiac atrium development GO:0003230 4 0.027
phosphate containing compound metabolic process GO:0006796 108 0.026
negative regulation of biological process GO:0048519 304 0.026
muscle cell development GO:0055001 115 0.026
regulation of organ morphogenesis GO:2000027 35 0.026
transport GO:0006810 220 0.026
epiboly GO:0090504 41 0.026
positive regulation of muscle cell differentiation GO:0051149 1 0.026
outflow tract morphogenesis GO:0003151 1 0.025
single organism organelle organization GO:1902589 199 0.025
synaptic growth at neuromuscular junction GO:0051124 2 0.025
notochord cell differentiation GO:0060034 18 0.025
tissue remodeling GO:0048771 4 0.025
cell projection assembly GO:0030031 64 0.025
ion transmembrane transport GO:0034220 91 0.025
negative regulation of cellular biosynthetic process GO:0031327 55 0.025
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.024
cell part morphogenesis GO:0032990 246 0.024
response to vitamin GO:0033273 3 0.024
regulation of meiotic cell cycle GO:0051445 1 0.024
single fertilization GO:0007338 3 0.024
response to mechanical stimulus GO:0009612 24 0.024
germ line stem cell maintenance GO:0030718 2 0.024
pigmentation GO:0043473 85 0.023
regulation of sarcomere organization GO:0060297 2 0.023
muscle cell fate determination GO:0007521 1 0.023
regulation of nucleoside metabolic process GO:0009118 2 0.023
cell migration involved in gastrulation GO:0042074 79 0.023
connective tissue development GO:0061448 99 0.023
epithelial cell differentiation GO:0030855 116 0.022
ion transport GO:0006811 114 0.022
cartilage development GO:0051216 96 0.022
negative regulation of translation GO:0017148 1 0.022
response to alkaloid GO:0043279 2 0.022
gastrulation with mouth forming second GO:0001702 44 0.022
regulation of cell projection assembly GO:0060491 4 0.022
fin development GO:0033333 77 0.022
regulation of muscle organ development GO:0048634 9 0.022
biosynthetic process GO:0009058 294 0.021
calcium ion homeostasis GO:0055074 19 0.021
cell morphogenesis involved in differentiation GO:0000904 195 0.021
myotube differentiation GO:0014902 45 0.021
regulation of signaling GO:0023051 235 0.021
regulation of tube size GO:0035150 2 0.021
negative regulation of blood circulation GO:1903523 2 0.021
regulation of skeletal muscle tissue development GO:0048641 4 0.021
regulation of blood vessel size GO:0050880 2 0.021
lipid oxidation GO:0034440 1 0.020
regulation of nitrogen compound metabolic process GO:0051171 251 0.020
regulation of primary metabolic process GO:0080090 311 0.020
ribonucleotide metabolic process GO:0009259 27 0.020
cation transport GO:0006812 81 0.020
neuron development GO:0048666 262 0.020
regulation of metal ion transport GO:0010959 4 0.020
endoderm development GO:0007492 49 0.019
regulation of macromolecule metabolic process GO:0060255 317 0.019
regulation of cell differentiation GO:0045595 142 0.019
regulation of n methyl d aspartate selective glutamate receptor activity GO:2000310 1 0.019
cellular biosynthetic process GO:0044249 286 0.019
cardiac myofibril assembly GO:0055003 9 0.019
positive regulation of muscle organ development GO:0048636 1 0.019
neurological system process GO:0050877 62 0.019
neural crest cell migration GO:0001755 42 0.019
regulation of stem cell proliferation GO:0072091 2 0.019
pectoral fin development GO:0033339 50 0.018
regulation of intracellular protein transport GO:0033157 3 0.018
positive regulation of cellular process GO:0048522 201 0.018
regulation of circadian rhythm GO:0042752 4 0.018
cell surface receptor signaling pathway GO:0007166 325 0.018
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.018
cellular calcium ion homeostasis GO:0006874 13 0.018
regulation of purine nucleotide metabolic process GO:1900542 17 0.018
regulation of neurogenesis GO:0050767 87 0.018
regulation of response to stimulus GO:0048583 269 0.018
cardiac ventricle formation GO:0003211 1 0.017
ventricular cardiac myofibril assembly GO:0055005 4 0.017
regulation of binding GO:0051098 3 0.017
somite development GO:0061053 96 0.017
organic cyclic compound metabolic process GO:1901360 301 0.017
glomerulus vasculature development GO:0072012 2 0.017
regulation of localization GO:0032879 104 0.017
rna stabilization GO:0043489 4 0.017
polarized epithelial cell differentiation GO:0030859 4 0.017
cellular response to unfolded protein GO:0034620 2 0.017
stem cell proliferation GO:0072089 4 0.017
post embryonic organ development GO:0048569 4 0.017
mesenchymal cell development GO:0014031 78 0.017
endocardial cushion formation GO:0003272 2 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.016
regulation of rac protein signal transduction GO:0035020 1 0.016
response to glucocorticoid GO:0051384 1 0.016
cellular macromolecule biosynthetic process GO:0034645 224 0.016
neuron projection development GO:0031175 180 0.016
intracellular signal transduction GO:0035556 85 0.016
muscle system process GO:0003012 20 0.016
regulation of filopodium assembly GO:0051489 2 0.016
regulation of protein complex assembly GO:0043254 3 0.016
endoplasmic reticulum unfolded protein response GO:0030968 2 0.016
regulation of mrna processing GO:0050684 3 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.016
actin cytoskeleton organization GO:0030036 63 0.016
growth GO:0040007 174 0.016
cellular response to oxygen levels GO:0071453 1 0.016
rna metabolic process GO:0016070 219 0.016
appendage development GO:0048736 80 0.015
somitogenesis GO:0001756 87 0.015
regulation of stem cell differentiation GO:2000736 4 0.015
regeneration GO:0031099 91 0.015
syncytium formation by plasma membrane fusion GO:0000768 12 0.015
positive regulation of striated muscle cell differentiation GO:0051155 1 0.015
cytokinesis GO:0000910 3 0.015
neural crest cell differentiation GO:0014033 72 0.015
cell fate commitment GO:0045165 99 0.015
protein complex biogenesis GO:0070271 30 0.015
regulation of receptor activity GO:0010469 2 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
regulation of gene expression GO:0010468 265 0.014
cell migration involved in mesendoderm migration GO:0090134 2 0.014
response to chemical GO:0042221 320 0.014
organic acid metabolic process GO:0006082 31 0.014
3 utr mediated mrna stabilization GO:0070935 3 0.014
establishment of protein localization to organelle GO:0072594 4 0.014
response to hormone GO:0009725 48 0.014
response to abiotic stimulus GO:0009628 122 0.014
syncytium formation GO:0006949 12 0.014
g1 s transition of mitotic cell cycle GO:0000082 1 0.014
mitochondrion organization GO:0007005 4 0.014
calcium ion transmembrane transport GO:0070588 13 0.014
heart field specification GO:0003128 1 0.014
atrial ventricular junction remodeling GO:0003294 2 0.014
mesenchymal cell proliferation GO:0010463 1 0.014
regulation of neurotransmitter transport GO:0051588 1 0.014
endocardial cushion morphogenesis GO:0003203 3 0.013
negative regulation of cellular process GO:0048523 283 0.013
protein targeting to membrane GO:0006612 1 0.013
regulation of ion transmembrane transport GO:0034765 18 0.013
regulation of cellular biosynthetic process GO:0031326 245 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.013
positive regulation of skeletal muscle tissue development GO:0048643 1 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
atrial cardiac muscle cell development GO:0055014 4 0.013
regulation of reproductive process GO:2000241 4 0.013
stem cell division GO:0017145 1 0.013
stem cell development GO:0048864 82 0.013
axonal fasciculation GO:0007413 11 0.013
regulation of synaptic plasticity GO:0048167 1 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.013
protein polymerization GO:0051258 4 0.013
small molecule metabolic process GO:0044281 77 0.013
muscle attachment GO:0016203 9 0.013
locomotor rhythm GO:0045475 3 0.013
behavior GO:0007610 74 0.013
protein metabolic process GO:0019538 183 0.013
blood vessel development GO:0001568 246 0.013
anterior posterior pattern specification GO:0009952 152 0.013
adherens junction maintenance GO:0034334 2 0.012
protein depolymerization GO:0051261 1 0.012
regulation of bone mineralization GO:0030500 2 0.012
chemical homeostasis GO:0048878 49 0.012
cell cycle g1 s phase transition GO:0044843 1 0.012
negative regulation of biosynthetic process GO:0009890 55 0.012
cell proliferation involved in heart morphogenesis GO:0061323 2 0.012
phosphorus metabolic process GO:0006793 109 0.012
lateral line system development GO:0048925 76 0.012
gtp catabolic process GO:0006184 2 0.012
proepicardium development GO:0003342 4 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.012
myofibril assembly GO:0030239 48 0.012
synapse organization GO:0050808 21 0.012
viral process GO:0016032 1 0.012
rna localization GO:0006403 4 0.011
cardiac muscle contraction GO:0060048 6 0.011
angiogenesis GO:0001525 158 0.011
monovalent inorganic cation transport GO:0015672 42 0.011
regulation of cell communication GO:0010646 232 0.011
actin mediated cell contraction GO:0070252 1 0.011
response to corticosteroid GO:0031960 1 0.011
multicellular organismal metabolic process GO:0044236 2 0.011
neural crest cell development GO:0014032 62 0.011
leukocyte homeostasis GO:0001776 2 0.011
interspecies interaction between organisms GO:0044419 4 0.011
dorsal convergence GO:0060030 14 0.011
morphogenesis of an epithelial sheet GO:0002011 49 0.011
mesoderm morphogenesis GO:0048332 51 0.011
actin polymerization or depolymerization GO:0008154 2 0.011
negative regulation of cellular metabolic process GO:0031324 77 0.011
lipid metabolic process GO:0006629 52 0.011
fatty acid catabolic process GO:0009062 1 0.011
liver development GO:0001889 96 0.011
cardiac cell fate commitment GO:0060911 1 0.011
regulation of mrna splicing via spliceosome GO:0048024 3 0.011
multicellular organismal response to stress GO:0033555 2 0.011
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.010
negative regulation of muscle tissue development GO:1901862 2 0.010
er nucleus signaling pathway GO:0006984 2 0.010
cellular component disassembly GO:0022411 1 0.010
positive regulation of cell adhesion GO:0045785 1 0.010
muscle cell fate commitment GO:0042693 9 0.010
nuclear import GO:0051170 3 0.010
organonitrogen compound metabolic process GO:1901564 74 0.010
cellular localization GO:0051641 97 0.010
organophosphate metabolic process GO:0019637 37 0.010
cellular protein metabolic process GO:0044267 129 0.010
cognition GO:0050890 1 0.010
regulation of epithelial cell proliferation GO:0050678 3 0.010

synpo2lb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.146
muscular disease DOID:0080000 0 0.146
heart disease DOID:114 0 0.146
cardiomyopathy DOID:0050700 0 0.146
disease of anatomical entity DOID:7 0 0.146
cardiovascular system disease DOID:1287 0 0.146
musculoskeletal system disease DOID:17 0 0.146
muscle tissue disease DOID:66 0 0.146
intrinsic cardiomyopathy DOID:0060036 0 0.099
hypertrophic cardiomyopathy DOID:11984 0 0.031
nervous system disease DOID:863 0 0.013
dilated cardiomyopathy DOID:12930 0 0.011