Danio rerio

0 known processes

tbcb

tubulin folding cofactor B

(Aliases: wu:fa56d03,ik:tdsubc_2e4,ckap1,xx:tdsubc_2e4,zgc:55620)

tbcb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.265
embryo development ending in birth or egg hatching GO:0009792 271 0.252
establishment of localization GO:0051234 244 0.191
fertilization GO:0009566 3 0.190
cellular macromolecule metabolic process GO:0044260 391 0.176
aging GO:0007568 2 0.173
single fertilization GO:0007338 3 0.115
cellular aromatic compound metabolic process GO:0006725 295 0.108
transport GO:0006810 220 0.101
modification dependent protein catabolic process GO:0019941 3 0.097
nucleoside monophosphate catabolic process GO:0009125 4 0.096
cortical cytoskeleton organization GO:0030865 1 0.092
single organism localization GO:1902578 225 0.088
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.086
response to stress GO:0006950 263 0.085
regulation of macromolecule metabolic process GO:0060255 317 0.084
cortical actin cytoskeleton organization GO:0030866 1 0.081
multi organism process GO:0051704 134 0.079
immune system process GO:0002376 241 0.079
nitrogen compound metabolic process GO:0006807 319 0.078
locomotion GO:0040011 313 0.078
cell motility GO:0048870 244 0.076
meiotic cell cycle process GO:1903046 3 0.074
cellular protein catabolic process GO:0044257 4 0.074
organic cyclic compound metabolic process GO:1901360 301 0.074
regulation of multicellular organism growth GO:0040014 4 0.073
proteasomal protein catabolic process GO:0010498 2 0.072
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.072
positive regulation of catabolic process GO:0009896 4 0.069
negative regulation of biological process GO:0048519 304 0.069
signal transduction GO:0007165 455 0.068
modification dependent macromolecule catabolic process GO:0043632 3 0.065
nucleobase containing compound metabolic process GO:0006139 274 0.065
pronuclear migration GO:0035046 1 0.063
negative regulation of cellular process GO:0048523 283 0.059
cellular nitrogen compound metabolic process GO:0034641 290 0.057
regulation of meiotic cell cycle GO:0051445 1 0.057
protein metabolic process GO:0019538 183 0.056
cellular component morphogenesis GO:0032989 336 0.056
cellular component movement GO:0006928 335 0.054
cell cycle g1 s phase transition GO:0044843 1 0.053
organelle organization GO:0006996 227 0.053
single organism metabolic process GO:0044710 217 0.053
multicellular organism growth GO:0035264 4 0.053
gene expression GO:0010467 252 0.053
cellular localization GO:0051641 97 0.052
microtubule organizing center organization GO:0031023 1 0.052
regulation of multicellular organismal process GO:0051239 277 0.052
purine nucleoside monophosphate catabolic process GO:0009128 4 0.051
cellular component biogenesis GO:0044085 178 0.050
ribonucleoside monophosphate catabolic process GO:0009158 4 0.050
regulation of apoptotic process GO:0042981 98 0.049
regulation of cell death GO:0010941 103 0.049
regulation of purine nucleotide catabolic process GO:0033121 2 0.048
positive regulation of cellular catabolic process GO:0031331 3 0.048
regulation of binding GO:0051098 3 0.048
meiotic nuclear division GO:0007126 4 0.048
regulation of signaling GO:0023051 235 0.047
positive regulation of cellular component biogenesis GO:0044089 3 0.045
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.045
death GO:0016265 121 0.044
negative regulation of response to stimulus GO:0048585 104 0.044
centrosome organization GO:0051297 1 0.044
regulation of establishment of protein localization GO:0070201 4 0.043
establishment of localization in cell GO:0051649 77 0.043
nuclear transport GO:0051169 4 0.043
ubiquitin dependent protein catabolic process GO:0006511 3 0.043
positive regulation of transport GO:0051050 2 0.042
growth GO:0040007 174 0.042
macromolecular complex subunit organization GO:0043933 74 0.042
regulation of cellular metabolic process GO:0031323 320 0.041
regulation of metabolic process GO:0019222 359 0.041
regulation of protein transport GO:0051223 3 0.041
regulation of signal transduction GO:0009966 225 0.040
g1 s transition of mitotic cell cycle GO:0000082 1 0.040
regulation of nucleic acid templated transcription GO:1903506 213 0.040
cell migration GO:0016477 237 0.040
intracellular signal transduction GO:0035556 85 0.040
small molecule metabolic process GO:0044281 77 0.039
negative regulation of cell communication GO:0010648 96 0.039
regulation of biological quality GO:0065008 263 0.039
localization of cell GO:0051674 244 0.039
transcription from rna polymerase ii promoter GO:0006366 80 0.038
stem cell proliferation GO:0072089 4 0.037
cellular protein metabolic process GO:0044267 129 0.037
cytoskeleton organization GO:0007010 96 0.037
negative regulation of signaling GO:0023057 96 0.036
cell morphogenesis GO:0000902 289 0.036
multicellular organism reproduction GO:0032504 35 0.036
regulation of primary metabolic process GO:0080090 311 0.036
negative regulation of cell death GO:0060548 60 0.036
protein complex subunit organization GO:0071822 46 0.035
response to external stimulus GO:0009605 264 0.035
morphogenesis of an epithelium GO:0002009 333 0.035
mitotic cell cycle GO:0000278 64 0.034
positive regulation of cell cycle GO:0045787 3 0.034
regulation of cytoplasmic transport GO:1903649 4 0.034
programmed cell death GO:0012501 119 0.034
immune system development GO:0002520 191 0.034
establishment of protein localization to organelle GO:0072594 4 0.034
heterocycle metabolic process GO:0046483 290 0.033
central nervous system development GO:0007417 387 0.033
neuroblast proliferation GO:0007405 2 0.033
cell death GO:0008219 121 0.033
meiosis i GO:0007127 1 0.033
regulation of response to stimulus GO:0048583 269 0.033
cellular response to external stimulus GO:0071496 2 0.032
regulation of cell projection assembly GO:0060491 4 0.031
response to other organism GO:0051707 97 0.031
centrosome cycle GO:0007098 1 0.031
apoptotic process GO:0006915 116 0.031
lipid storage GO:0019915 1 0.031
regulation of nitrogen compound metabolic process GO:0051171 251 0.031
regulation of biosynthetic process GO:0009889 250 0.030
atp catabolic process GO:0006200 4 0.030
rna metabolic process GO:0016070 219 0.030
macromolecule modification GO:0043412 111 0.030
cytoskeleton dependent cytokinesis GO:0061640 3 0.030
cell proliferation GO:0008283 80 0.029
organic acid metabolic process GO:0006082 31 0.029
dna templated transcription initiation GO:0006352 1 0.029
cellular component assembly GO:0022607 170 0.029
positive regulation of cellular process GO:0048522 201 0.028
meiotic chromosome segregation GO:0045132 3 0.028
single organism organelle organization GO:1902589 199 0.028
maintenance of location GO:0051235 4 0.028
nuclear migration GO:0007097 3 0.028
nucleocytoplasmic transport GO:0006913 4 0.027
response to biotic stimulus GO:0009607 97 0.027
regulation of protein catabolic process GO:0042176 1 0.027
hematopoietic or lymphoid organ development GO:0048534 191 0.027
single organism transport GO:0044765 206 0.027
cellular response to chemical stimulus GO:0070887 157 0.027
protein dephosphorylation GO:0006470 3 0.027
negative regulation of protein phosphorylation GO:0001933 4 0.027
regulation of gene expression GO:0010468 265 0.026
regulation of protein complex assembly GO:0043254 3 0.026
regulation of oocyte development GO:0060281 3 0.025
positive regulation of biological process GO:0048518 253 0.025
regulation of intracellular protein transport GO:0033157 3 0.025
positive regulation of nucleotide catabolic process GO:0030813 1 0.025
response to topologically incorrect protein GO:0035966 2 0.025
mitochondrion organization GO:0007005 4 0.025
establishment of organelle localization GO:0051656 45 0.025
hatching GO:0035188 4 0.025
cellular protein modification process GO:0006464 100 0.025
actin cytoskeleton organization GO:0030036 63 0.025
regulation of nucleotide catabolic process GO:0030811 2 0.025
female sex differentiation GO:0046660 4 0.024
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.024
cellular amine metabolic process GO:0044106 2 0.024
regulation of protein ubiquitination GO:0031396 3 0.024
organic substance biosynthetic process GO:1901576 289 0.024
organonitrogen compound metabolic process GO:1901564 74 0.024
regulation of nucleocytoplasmic transport GO:0046822 2 0.024
developmental growth GO:0048589 166 0.024
regulation of cell shape GO:0008360 1 0.024
cellular component disassembly GO:0022411 1 0.024
negative regulation of gene expression GO:0010629 65 0.024
regulation of programmed cell death GO:0043067 101 0.023
autophagy GO:0006914 4 0.023
regulation of rna biosynthetic process GO:2001141 213 0.023
guanosine containing compound metabolic process GO:1901068 4 0.023
protein import GO:0017038 3 0.023
somitogenesis GO:0001756 87 0.023
regulation of cell communication GO:0010646 232 0.023
response to external biotic stimulus GO:0043207 97 0.023
cellular macromolecule biosynthetic process GO:0034645 224 0.023
cell surface receptor signaling pathway GO:0007166 325 0.022
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.022
chordate embryonic development GO:0043009 271 0.022
regulation of cellular amine metabolic process GO:0033238 0 0.021
cellular biosynthetic process GO:0044249 286 0.021
regulation of stem cell differentiation GO:2000736 4 0.021
development of primary female sexual characteristics GO:0046545 4 0.021
regulation of tube size GO:0035150 2 0.021
organic cyclic compound biosynthetic process GO:1901362 223 0.021
striated muscle cell development GO:0055002 108 0.021
macromolecular complex assembly GO:0065003 35 0.021
response to chemical GO:0042221 320 0.021
muscle cell differentiation GO:0042692 139 0.021
aromatic compound biosynthetic process GO:0019438 217 0.021
positive regulation of map kinase activity GO:0043406 3 0.021
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.021
regulation of protein targeting GO:1903533 2 0.021
stem cell division GO:0017145 1 0.020
negative regulation of apoptotic process GO:0043066 55 0.020
single organism membrane fusion GO:0044801 2 0.020
regulation of mrna processing GO:0050684 3 0.020
organelle fusion GO:0048284 3 0.020
spermatid differentiation GO:0048515 2 0.020
negative regulation of signal transduction GO:0009968 94 0.020
sensory organ development GO:0007423 393 0.020
cell cycle process GO:0022402 53 0.020
single organism nuclear import GO:1902593 3 0.020
regulation of nucleoside metabolic process GO:0009118 2 0.020
cytokinesis GO:0000910 3 0.020
gtp metabolic process GO:0046039 4 0.020
heterocycle biosynthetic process GO:0018130 215 0.020
regulation of epithelial cell proliferation GO:0050678 3 0.020
hemopoiesis GO:0030097 183 0.020
camera type eye development GO:0043010 222 0.020
stem cell maintenance GO:0019827 4 0.019
organic substance transport GO:0071702 58 0.019
i kappab kinase nf kappab signaling GO:0007249 4 0.019
nuclear division GO:0000280 23 0.019
system process GO:0003008 185 0.019
peptidyl serine phosphorylation GO:0018105 1 0.019
organelle assembly GO:0070925 110 0.019
negative regulation of programmed cell death GO:0043069 58 0.019
homeostatic process GO:0042592 142 0.019
glial cell migration GO:0008347 3 0.019
protein complex assembly GO:0006461 30 0.019
amine metabolic process GO:0009308 2 0.019
signal transduction in absence of ligand GO:0038034 1 0.019
heart development GO:0007507 313 0.019
organism emergence from protective structure GO:0071684 4 0.019
anterior posterior pattern specification GO:0009952 152 0.019
response to wounding GO:0009611 116 0.019
mitotic cell cycle process GO:1903047 48 0.018
double strand break repair GO:0006302 3 0.018
regionalization GO:0003002 274 0.018
regulation of synapse assembly GO:0051963 3 0.018
organelle localization GO:0051640 49 0.018
cellular response to extracellular stimulus GO:0031668 2 0.018
head development GO:0060322 303 0.018
oxoacid metabolic process GO:0043436 31 0.018
small gtpase mediated signal transduction GO:0007264 8 0.018
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.018
carbohydrate biosynthetic process GO:0016051 1 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
biosynthetic process GO:0009058 294 0.018
muscle structure development GO:0061061 196 0.017
extrinsic apoptotic signaling pathway GO:0097191 3 0.017
mitotic recombination GO:0006312 2 0.017
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.017
regulation of cellular ketone metabolic process GO:0010565 7 0.017
pole plasm assembly GO:0007315 4 0.017
regulation of developmental process GO:0050793 247 0.017
ovulation cycle GO:0042698 2 0.017
rna localization GO:0006403 4 0.017
sensory perception of pain GO:0019233 1 0.017
carboxylic acid metabolic process GO:0019752 22 0.017
regulation of protein localization to nucleus GO:1900180 2 0.017
regulation of multicellular organismal development GO:2000026 223 0.017
positive regulation of secretion GO:0051047 1 0.017
segmentation GO:0035282 97 0.017
spindle assembly GO:0051225 2 0.017
regulation of protein import into nucleus GO:0042306 2 0.017
organic substance catabolic process GO:1901575 28 0.017
cellular amino acid metabolic process GO:0006520 7 0.017
intracellular transport GO:0046907 32 0.016
microtubule cytoskeleton organization GO:0000226 33 0.016
nuclear import GO:0051170 3 0.016
germ line stem cell maintenance GO:0030718 2 0.016
generation of neurons GO:0048699 385 0.016
positive regulation of nucleoside metabolic process GO:0045979 1 0.016
regulation of wound healing GO:0061041 2 0.016
regulation of protein binding GO:0043393 3 0.016
double strand break repair via homologous recombination GO:0000724 1 0.016
positive regulation of metabolic process GO:0009893 108 0.016
gtp catabolic process GO:0006184 2 0.016
macromolecule biosynthetic process GO:0009059 227 0.016
regulation of localization GO:0032879 104 0.016
energy reserve metabolic process GO:0006112 2 0.016
maturation of ssu rrna GO:0030490 1 0.016
cell projection organization GO:0030030 284 0.016
compound eye development GO:0048749 2 0.016
cytokinetic process GO:0032506 2 0.016
oocyte anterior posterior axis specification GO:0007314 4 0.016
neuron development GO:0048666 262 0.015
regulation of reproductive process GO:2000241 4 0.015
actin filament based process GO:0030029 64 0.015
olfactory lobe development GO:0021988 4 0.015
negative regulation of protein kinase activity GO:0006469 4 0.015
cilium morphogenesis GO:0060271 85 0.015
protein modification process GO:0036211 100 0.015
protein polymerization GO:0051258 4 0.015
endosomal transport GO:0016197 2 0.015
protein import into nucleus GO:0006606 3 0.015
alternative mrna splicing via spliceosome GO:0000380 1 0.015
negative regulation of cytoplasmic transport GO:1903650 2 0.015
phosphate containing compound metabolic process GO:0006796 108 0.015
protein targeting to nucleus GO:0044744 3 0.015
sexual reproduction GO:0019953 36 0.015
muscle cell development GO:0055001 115 0.015
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.015
regulation of cell proliferation GO:0042127 37 0.015
peptide transport GO:0015833 1 0.015
regulation of synapse organization GO:0050807 3 0.015
negative regulation of kinase activity GO:0033673 4 0.015
synaptic growth at neuromuscular junction GO:0051124 2 0.015
protein secretion GO:0009306 1 0.015
somite development GO:0061053 96 0.015
regulation of organelle organization GO:0033043 29 0.015
regulation of blood vessel size GO:0050880 2 0.015
neuron differentiation GO:0030182 353 0.015
cellular component assembly involved in morphogenesis GO:0010927 107 0.014
regulation of cell activation GO:0050865 1 0.014
regulation of protein metabolic process GO:0051246 56 0.014
cellular ketone metabolic process GO:0042180 11 0.014
homeostasis of number of cells GO:0048872 62 0.014
tube morphogenesis GO:0035239 349 0.014
secondary metabolic process GO:0019748 3 0.014
protein complex biogenesis GO:0070271 30 0.014
regulation of jun kinase activity GO:0043506 3 0.014
regulation of intracellular signal transduction GO:1902531 57 0.014
response to organic substance GO:0010033 153 0.014
cell cycle GO:0007049 93 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
negative regulation of protein transport GO:0051224 3 0.014
apoptotic process involved in development GO:1902742 2 0.014
multicellular organismal reproductive process GO:0048609 35 0.014
cellular response to stress GO:0033554 62 0.013
microtubule based process GO:0007017 60 0.013
b cell activation GO:0042113 2 0.013
ribosomal small subunit biogenesis GO:0042274 2 0.013
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.013
female gonad development GO:0008585 4 0.013
neurotransmitter transport GO:0006836 2 0.013
phosphorus metabolic process GO:0006793 109 0.013
cellular response to starvation GO:0009267 1 0.013
reproduction GO:0000003 40 0.013
cell projection morphogenesis GO:0048858 244 0.013
positive regulation of protein complex assembly GO:0031334 2 0.013
convergent extension GO:0060026 118 0.013
actin polymerization or depolymerization GO:0008154 2 0.013
spermatid development GO:0007286 2 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.013
eye development GO:0001654 277 0.013
cytoplasm organization GO:0007028 4 0.013
digestive system development GO:0055123 289 0.013
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
establishment or maintenance of cell polarity GO:0007163 29 0.013
positive regulation of gtp catabolic process GO:0033126 1 0.013
regulation of cytokine production GO:0001817 3 0.013
membrane fusion GO:0061025 2 0.013
tissue remodeling GO:0048771 4 0.012
response to nutrient GO:0007584 3 0.012
positive regulation of wound healing GO:0090303 1 0.012
regulation of wnt signaling pathway GO:0030111 53 0.012
regulation of molecular function GO:0065009 70 0.012
vasculature development GO:0001944 278 0.012
striated muscle cell differentiation GO:0051146 129 0.012
antimicrobial humoral response GO:0019730 2 0.012
meiosis ii GO:0007135 1 0.012
protein complex disassembly GO:0043241 1 0.012
positive regulation of secretion by cell GO:1903532 1 0.012
protein homooligomerization GO:0051260 3 0.012
nucleic acid transport GO:0050657 2 0.012
chromosome organization involved in meiosis GO:0070192 1 0.012
cellular nitrogen compound biosynthetic process GO:0044271 218 0.012
response to hydrogen peroxide GO:0042542 3 0.012
single organism cellular localization GO:1902580 46 0.012
myeloid cell homeostasis GO:0002262 56 0.012
cellular response to topologically incorrect protein GO:0035967 2 0.012
cellular macromolecule catabolic process GO:0044265 12 0.012
embryonic organ development GO:0048568 381 0.012
macromolecule localization GO:0033036 54 0.012
transcription dna templated GO:0006351 181 0.012
nucleic acid templated transcription GO:0097659 181 0.012
er nucleus signaling pathway GO:0006984 2 0.012
regulation of cellular protein metabolic process GO:0032268 52 0.012
cell part morphogenesis GO:0032990 246 0.012
gamete generation GO:0007276 33 0.012
lymphocyte proliferation GO:0046651 1 0.012
maternal determination of anterior posterior axis embryo GO:0008358 4 0.012
gland development GO:0048732 143 0.011
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.011
negative regulation of synapse assembly GO:0051964 2 0.011
protein localization to nucleus GO:0034504 3 0.011
mitotic cytokinesis GO:0000281 3 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.011
embryonic limb morphogenesis GO:0030326 2 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
myeloid cell differentiation GO:0030099 86 0.011
negative regulation of epithelial cell proliferation GO:0050680 1 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
cellular carbohydrate metabolic process GO:0044262 4 0.011
regulation of cell differentiation GO:0045595 142 0.011
macroautophagy GO:0016236 1 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
rna transport GO:0050658 2 0.011
regulation of inflammatory response GO:0050727 2 0.011
transcription from rna polymerase iii promoter GO:0006383 1 0.011
immune response GO:0006955 28 0.011
positive regulation of gene expression GO:0010628 71 0.011
mitochondrial transport GO:0006839 2 0.011
melanin metabolic process GO:0006582 2 0.011
mononuclear cell proliferation GO:0032943 1 0.011
cellular response to nutrient levels GO:0031669 2 0.011
synaptic vesicle localization GO:0097479 1 0.011
positive regulation of neuron death GO:1901216 1 0.011
macromolecular complex disassembly GO:0032984 1 0.011
nuclear export GO:0051168 1 0.011
positive regulation of programmed cell death GO:0043068 29 0.011
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.011
gastrulation GO:0007369 208 0.011
developmental programmed cell death GO:0010623 4 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
peptidyl serine modification GO:0018209 2 0.011
b cell differentiation GO:0030183 1 0.011
protein stabilization GO:0050821 2 0.011
regulation of carbohydrate metabolic process GO:0006109 4 0.010
positive regulation of cell division GO:0051781 2 0.010
positive regulation of apoptotic signaling pathway GO:2001235 1 0.010
intestinal absorption GO:0050892 2 0.010
guanosine containing compound catabolic process GO:1901069 2 0.010
positive regulation of stem cell proliferation GO:2000648 1 0.010
tyrosine phosphorylation of stat protein GO:0007260 1 0.010
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.010
single organism reproductive process GO:0044702 40 0.010
regulation of gtpase activity GO:0043087 2 0.010
catabolic process GO:0009056 32 0.010
chemosensory behavior GO:0007635 1 0.010
negative regulation of intracellular transport GO:0032387 3 0.010
positive regulation of cell activation GO:0050867 1 0.010
erythrocyte homeostasis GO:0034101 55 0.010
response to uv GO:0009411 3 0.010
exocrine system development GO:0035272 28 0.010
negative regulation of map kinase activity GO:0043407 2 0.010

tbcb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.014
sensory system disease DOID:0050155 0 0.013
disease of metabolism DOID:0014667 0 0.012
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.011
eye and adnexa disease DOID:1492 0 0.010
eye disease DOID:5614 0 0.010