Danio rerio

107 known processes

tbx1

T-box 1

(Aliases: mp:zf637-3-000616,MGC136724,zgc:136724)

tbx1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryonic organ development GO:0048568 381 1.000
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 1.000
Zebrafish
heart jogging GO:0003146 40 1.000
Zebrafish
heart development GO:0007507 313 1.000
endocardial cushion development GO:0003197 6 1.000
embryonic organ morphogenesis GO:0048562 274 1.000
cell differentiation in spinal cord GO:0021515 40 1.000
Zebrafish
outflow tract morphogenesis GO:0003151 1 1.000
Mouse
heart morphogenesis GO:0003007 156 1.000
artery development GO:0060840 22 1.000
Mouse
cell surface receptor signaling pathway involved in heart development GO:0061311 20 1.000
Zebrafish
regulation of cell communication GO:0010646 232 0.999
Zebrafish Mouse
inner ear development GO:0048839 126 0.999
diencephalon development GO:0021536 58 0.999
Zebrafish
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.999
neuron differentiation GO:0030182 353 0.999
Zebrafish
heart formation GO:0060914 13 0.999
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.999
endocardial cushion formation GO:0003272 2 0.999
regulation of heart morphogenesis GO:2000826 17 0.998
embryonic camera type eye formation GO:0060900 10 0.998
sensory organ morphogenesis GO:0090596 200 0.998
connective tissue development GO:0061448 99 0.998
inner ear receptor cell differentiation GO:0060113 29 0.998
central nervous system development GO:0007417 387 0.998
Zebrafish Mouse
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.998
endocardium development GO:0003157 9 0.998
tube morphogenesis GO:0035239 349 0.998
neural crest cell differentiation GO:0014033 72 0.997
cell motility GO:0048870 244 0.997
chordate embryonic development GO:0043009 271 0.997
endocrine system development GO:0035270 65 0.997
Mouse
regulation of signal transduction GO:0009966 225 0.997
Zebrafish Mouse
regulation of apoptotic process GO:0042981 98 0.997
Mouse
cardiac muscle tissue morphogenesis GO:0055008 7 0.997
head development GO:0060322 303 0.997
Zebrafish Mouse
determination of bilateral symmetry GO:0009855 204 0.996
embryonic camera type eye development GO:0031076 29 0.996
positive regulation of muscle organ development GO:0048636 1 0.996
Mouse
localization of cell GO:0051674 244 0.996
cartilage development GO:0051216 96 0.996
specification of symmetry GO:0009799 204 0.996
neural tube development GO:0021915 62 0.996
optic placode formation GO:0001743 4 0.996
signal transduction GO:0007165 455 0.996
Zebrafish Mouse
urogenital system development GO:0001655 97 0.995
Zebrafish
liver development GO:0001889 96 0.995
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.995
optic placode formation involved in camera type eye formation GO:0046619 3 0.995
cell migration involved in gastrulation GO:0042074 79 0.994
Zebrafish
cardiac chamber development GO:0003205 19 0.994
Zebrafish Mouse
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.994
central nervous system neuron differentiation GO:0021953 74 0.994
Zebrafish
cell surface receptor signaling pathway GO:0007166 325 0.993
Zebrafish
embryonic digestive tract morphogenesis GO:0048557 3 0.993
endocardial cushion morphogenesis GO:0003203 3 0.993
cardiac chamber morphogenesis GO:0003206 12 0.993
Mouse
endocardium morphogenesis GO:0003160 4 0.992
cell proliferation involved in heart morphogenesis GO:0061323 2 0.992
cell migration involved in heart development GO:0060973 22 0.992
gland development GO:0048732 143 0.992
Mouse
brain development GO:0007420 293 0.992
Zebrafish
regionalization GO:0003002 274 0.992
Zebrafish Mouse
cardioblast migration to the midline involved in heart rudiment formation GO:0003319 5 0.992
muscle structure development GO:0061061 196 0.992
heart looping GO:0001947 94 0.991
segment polarity determination GO:0007367 1 0.991
cardiac atrium morphogenesis GO:0003209 2 0.991
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.991
muscle tissue development GO:0060537 110 0.991
neuron fate commitment GO:0048663 26 0.990
Zebrafish
embryonic heart tube morphogenesis GO:0003143 108 0.990
odontogenesis of dentin containing tooth GO:0042475 1 0.990
Mouse
cell migration GO:0016477 237 0.989
cardiac muscle tissue development GO:0048738 48 0.989
regulation of epithelial cell proliferation GO:0050678 3 0.989
Mouse
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.988
otic vesicle formation GO:0030916 27 0.988
morphogenesis of an epithelium GO:0002009 333 0.988
determination of left right symmetry GO:0007368 179 0.987
striated muscle tissue development GO:0014706 110 0.987
auditory receptor cell differentiation GO:0042491 15 0.987
kidney development GO:0001822 92 0.987
Zebrafish
pancreas development GO:0031016 84 0.987
negative regulation of response to stimulus GO:0048585 104 0.986
regulation of anatomical structure morphogenesis GO:0022603 130 0.986
regulation of signaling GO:0023051 235 0.986
Zebrafish Mouse
regulation of organ growth GO:0046620 3 0.986
embryonic cranial skeleton morphogenesis GO:0048701 90 0.985
Mouse
spinal cord development GO:0021510 46 0.984
Zebrafish
vasculature development GO:0001944 278 0.984
Zebrafish Mouse
cell fate commitment GO:0045165 99 0.984
Zebrafish Mouse
sensory organ development GO:0007423 393 0.984
cell morphogenesis involved in differentiation GO:0000904 195 0.983
Zebrafish
heart rudiment formation GO:0003315 5 0.982
pectoral fin development GO:0033339 50 0.981
Zebrafish
bmp signaling pathway involved in heart jogging GO:0003303 14 0.981
Zebrafish
cardiocyte differentiation GO:0035051 44 0.981
rostrocaudal neural tube patterning GO:0021903 29 0.980
somite development GO:0061053 96 0.980
Zebrafish
cardiogenic plate morphogenesis GO:0003142 1 0.980
artery morphogenesis GO:0048844 14 0.980
Mouse
vasculogenesis GO:0001570 41 0.980
Zebrafish
cellular response to chemical stimulus GO:0070887 157 0.980
Mouse
embryonic eye morphogenesis GO:0048048 30 0.980
epithalamus development GO:0021538 10 0.979
Zebrafish
mesenchyme development GO:0060485 127 0.979
embryonic pectoral fin morphogenesis GO:0035118 24 0.979
Zebrafish
aorta morphogenesis GO:0035909 3 0.978
Mouse
mechanoreceptor differentiation GO:0042490 37 0.978
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.978
Zebrafish
forebrain development GO:0030900 96 0.977
Zebrafish
regulation of neurogenesis GO:0050767 87 0.976
embryonic heart tube development GO:0035050 133 0.975
pituitary gland development GO:0021983 16 0.975
gall bladder development GO:0061010 1 0.975
oligodendrocyte differentiation GO:0048709 23 0.975
spinal cord anterior posterior patterning GO:0021512 1 0.974
hepatic duct development GO:0061011 2 0.974
otic placode formation GO:0043049 23 0.972
patterning of blood vessels GO:0001569 15 0.972
skeletal system development GO:0001501 181 0.971
nerve development GO:0021675 45 0.969
Zebrafish Mouse
digestive tract development GO:0048565 265 0.969
determination of heart left right asymmetry GO:0061371 117 0.967
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 15 0.967
Zebrafish
aorta development GO:0035904 4 0.967
Mouse
positive regulation of skeletal muscle tissue development GO:0048643 1 0.965
Mouse
embryonic pattern specification GO:0009880 44 0.965
epithelial tube morphogenesis GO:0060562 148 0.965
forebrain generation of neurons GO:0021872 14 0.964
endocrine pancreas development GO:0031018 27 0.963
nephron development GO:0072006 31 0.963
hematopoietic progenitor cell differentiation GO:0002244 23 0.960
Zebrafish
positive regulation of striated muscle tissue development GO:0045844 1 0.960
Mouse
cellular component morphogenesis GO:0032989 336 0.960
Zebrafish
blood vessel morphogenesis GO:0048514 216 0.959
Zebrafish Mouse
germ line stem cell division GO:0042078 1 0.958
neural tube patterning GO:0021532 33 0.958
angiogenesis GO:0001525 158 0.958
Zebrafish Mouse
hepaticobiliary system development GO:0061008 98 0.958
regeneration GO:0031099 91 0.957
habenula development GO:0021986 9 0.956
ear development GO:0043583 127 0.954
retinal ganglion cell axon guidance GO:0031290 35 0.952
glial cell differentiation GO:0010001 42 0.952
specification of organ identity GO:0010092 2 0.952
stem cell proliferation GO:0072089 4 0.951
Mouse
regulation of cell development GO:0060284 100 0.949
auditory receptor cell fate commitment GO:0009912 4 0.949
cellular component movement GO:0006928 335 0.949
inner ear morphogenesis GO:0042472 63 0.948
mesenchymal cell development GO:0014031 78 0.948
renal system development GO:0072001 94 0.948
Zebrafish
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.947
Zebrafish
notochord development GO:0030903 54 0.947
Zebrafish
mesoderm development GO:0007498 88 0.946
Zebrafish Mouse
mesodermal cell fate commitment GO:0001710 14 0.945
heart valve morphogenesis GO:0003179 8 0.945
Zebrafish
embryonic viscerocranium morphogenesis GO:0048703 52 0.945
epithelial to mesenchymal transition GO:0001837 21 0.944
Zebrafish
response to external stimulus GO:0009605 264 0.944
kidney epithelium development GO:0072073 23 0.943
Zebrafish
negative regulation of multicellular organismal process GO:0051241 69 0.943
bmp signaling pathway involved in determination of left right symmetry GO:0003154 14 0.942
Zebrafish
regulation of neuron projection development GO:0010975 40 0.941
regulation of cardiac muscle tissue development GO:0055024 1 0.941
embryonic camera type eye morphogenesis GO:0048596 19 0.941
nephron epithelium development GO:0072009 16 0.939
embryonic digestive tract development GO:0048566 4 0.938
embryonic skeletal system morphogenesis GO:0048704 93 0.936
Mouse
hemopoiesis GO:0030097 183 0.936
Zebrafish
mesenchymal cell differentiation GO:0048762 87 0.935
biosynthetic process GO:0009058 294 0.932
Zebrafish Mouse Fly
regulation of anterior head development GO:2000742 2 0.931
regulation of nucleic acid templated transcription GO:1903506 213 0.931
Zebrafish Mouse Fly
transcription dna templated GO:0006351 181 0.930
Zebrafish Mouse Fly
determination of left right asymmetry in lateral mesoderm GO:0003140 20 0.930
Zebrafish
cell morphogenesis GO:0000902 289 0.930
Zebrafish
mesoderm formation GO:0001707 43 0.929
Zebrafish
hepatocyte proliferation GO:0072574 2 0.928
enzyme linked receptor protein signaling pathway GO:0007167 106 0.928
Zebrafish
floor plate formation GO:0021508 12 0.926
cardiac ventricle development GO:0003231 9 0.925
otic vesicle morphogenesis GO:0071600 34 0.925
Mouse
positive regulation of epithelial cell proliferation GO:0050679 1 0.925
Mouse
ectodermal placode formation GO:0060788 26 0.925
ventricular cardiac muscle tissue development GO:0003229 3 0.923
heart valve formation GO:0003188 4 0.920
Zebrafish
heart field specification GO:0003128 1 0.920
blood vessel endothelial cell differentiation GO:0060837 2 0.919
inner ear receptor cell fate commitment GO:0060120 4 0.919
developmental growth involved in morphogenesis GO:0060560 86 0.918
Zebrafish
regulation of muscle organ development GO:0048634 9 0.917
Mouse
hair cell differentiation GO:0035315 32 0.916
regulation of multicellular organismal process GO:0051239 277 0.913
limb bud formation GO:0060174 2 0.911
Zebrafish
striated muscle cell differentiation GO:0051146 129 0.910
death GO:0016265 121 0.902
Mouse
locomotion GO:0040011 313 0.901
cardiac ventricle morphogenesis GO:0003208 7 0.897
thyroid gland development GO:0030878 12 0.897
Mouse
atrioventricular valve formation GO:0003190 3 0.895
Zebrafish
ear morphogenesis GO:0042471 64 0.895
negative regulation of apoptotic process GO:0043066 55 0.895
Mouse
mesoderm morphogenesis GO:0048332 51 0.891
Zebrafish
embryonic neurocranium morphogenesis GO:0048702 15 0.891
regulation of cell proliferation GO:0042127 37 0.890
skeletal muscle organ development GO:0060538 78 0.889
Mouse
positive regulation of rna metabolic process GO:0051254 59 0.889
Zebrafish Mouse Fly
otic vesicle development GO:0071599 42 0.887
Mouse
blood vessel development GO:0001568 246 0.886
Zebrafish Mouse
organ formation GO:0048645 17 0.882
nephron epithelium morphogenesis GO:0072088 1 0.882
cellular macromolecule metabolic process GO:0044260 391 0.881
Zebrafish Mouse Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.881
Zebrafish Mouse Fly
heart process GO:0003015 71 0.877
Zebrafish
regulation of heart growth GO:0060420 2 0.876
ectodermal placode development GO:0071696 37 0.872
positive regulation of programmed cell death GO:0043068 29 0.867
regulation of wnt signaling pathway involved in heart development GO:0003307 2 0.867
branching morphogenesis of an epithelial tube GO:0048754 15 0.866
endodermal cell fate specification GO:0001714 17 0.865
Zebrafish
fin morphogenesis GO:0033334 53 0.865
Zebrafish
floor plate development GO:0033504 15 0.865
heart rudiment morphogenesis GO:0003314 6 0.865
pharyngeal system development GO:0060037 18 0.864
apoptotic process GO:0006915 116 0.863
Mouse
negative regulation of cell death GO:0060548 60 0.863
Mouse
negative regulation of signaling GO:0023057 96 0.863
dorsal convergence GO:0060030 14 0.861
embryo development ending in birth or egg hatching GO:0009792 271 0.860
motor neuron axon guidance GO:0008045 23 0.856
organic cyclic compound biosynthetic process GO:1901362 223 0.854
Zebrafish Mouse Fly
regulation of programmed cell death GO:0043067 101 0.852
Mouse
axon guidance GO:0007411 86 0.852
regulation of axonogenesis GO:0050770 32 0.846
heterocycle metabolic process GO:0046483 290 0.845
Zebrafish Mouse Fly
muscle cell fate commitment GO:0042693 9 0.844
Mouse
stem cell differentiation GO:0048863 117 0.842
segmentation GO:0035282 97 0.837
Zebrafish
negative regulation of signal transduction GO:0009968 94 0.837
regulation of multicellular organismal development GO:2000026 223 0.836
embryonic skeletal system development GO:0048706 97 0.835
Mouse
neuron development GO:0048666 262 0.835
Zebrafish
endocardium formation GO:0060214 1 0.833
nucleobase containing compound biosynthetic process GO:0034654 205 0.833
Zebrafish Mouse Fly
periodic partitioning GO:0007365 1 0.830
neural plate development GO:0001840 10 0.830
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.829
Zebrafish Mouse
negative regulation of axon guidance GO:1902668 1 0.828
otolith development GO:0048840 32 0.826
neuron projection guidance GO:0097485 86 0.824
wnt signaling pathway GO:0016055 80 0.823
positive regulation of muscle tissue development GO:1901863 1 0.820
Mouse
anterior posterior axon guidance GO:0033564 5 0.817
muscle cell differentiation GO:0042692 139 0.811
morphogenesis of a branching structure GO:0001763 21 0.808
appendage development GO:0048736 80 0.808
Zebrafish
regulation of skeletal muscle tissue development GO:0048641 4 0.805
Mouse
negative regulation of gene expression GO:0010629 65 0.804
Zebrafish Mouse
gliogenesis GO:0042063 45 0.803
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.803
Mouse
regulation of cell fate commitment GO:0010453 22 0.796
adenohypophysis development GO:0021984 15 0.791
morphogenesis of an epithelial fold GO:0060571 1 0.789
Zebrafish
programmed cell death GO:0012501 119 0.789
Mouse
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.787
nephron tubule morphogenesis GO:0072078 1 0.787
regulation of axon guidance GO:1902667 8 0.786
convergent extension involved in gastrulation GO:0060027 71 0.785
lateral mesoderm development GO:0048368 23 0.785
Zebrafish
regulation of organ morphogenesis GO:2000027 35 0.784
mesenchyme morphogenesis GO:0072132 5 0.779
mesodermal cell fate specification GO:0007501 12 0.775
neuron projection development GO:0031175 180 0.775
midbrain hindbrain boundary development GO:0030917 23 0.769
taxis GO:0042330 109 0.768
inner ear receptor cell development GO:0060119 20 0.765
morphogenesis of a branching epithelium GO:0061138 16 0.764
gastrulation GO:0007369 208 0.762
Zebrafish
tissue remodeling GO:0048771 4 0.761
Zebrafish Mouse
epidermal cell differentiation GO:0009913 36 0.761
positive regulation of apoptotic process GO:0043065 29 0.758
negative regulation of cell communication GO:0010648 96 0.756
floor plate morphogenesis GO:0033505 12 0.755
positive regulation of gene expression GO:0010628 71 0.755
Zebrafish Mouse Fly
regulation of cartilage development GO:0061035 7 0.755
digestive system development GO:0055123 289 0.754
immune system development GO:0002520 191 0.753
Zebrafish Mouse
rna metabolic process GO:0016070 219 0.750
Zebrafish Mouse Fly
somatic stem cell maintenance GO:0035019 1 0.747
forebrain neuron differentiation GO:0021879 14 0.746
heart contraction GO:0060047 71 0.744
Zebrafish
ectodermal placode morphogenesis GO:0071697 32 0.744
somitogenesis GO:0001756 87 0.743
Zebrafish
stem cell maintenance GO:0019827 4 0.742
forebrain regionalization GO:0021871 4 0.742
cell death GO:0008219 121 0.741
Mouse
mediolateral intercalation GO:0060031 3 0.739
glomerulus development GO:0032835 27 0.736
axon development GO:0061564 166 0.733
bmp signaling pathway involved in heart development GO:0061312 15 0.732
Zebrafish
rna biosynthetic process GO:0032774 181 0.732
Zebrafish Mouse Fly
specification of organ position GO:0010159 3 0.730
Zebrafish
odontogenesis GO:0042476 9 0.724
Mouse
stem cell development GO:0048864 82 0.723
atrial ventricular junction remodeling GO:0003294 2 0.723
Zebrafish
renal tubule morphogenesis GO:0061333 1 0.720
nuclear transport GO:0051169 4 0.718
neuron projection extension involved in neuron projection guidance GO:1902284 10 0.718
cell proliferation GO:0008283 80 0.713
nitrogen compound metabolic process GO:0006807 319 0.712
Zebrafish Mouse Fly
dorsal ventral axis specification GO:0009950 14 0.711
negative regulation of programmed cell death GO:0043069 58 0.710
Mouse
regulation of mesodermal cell fate specification GO:0042661 9 0.709
cellular macromolecule biosynthetic process GO:0034645 224 0.706
Zebrafish Mouse Fly
proepicardium development GO:0003342 4 0.705
Zebrafish
ventral spinal cord development GO:0021517 35 0.700
Zebrafish
stem cell division GO:0017145 1 0.699
positive regulation of cellular biosynthetic process GO:0031328 68 0.695
Zebrafish Mouse Fly
response to growth factor GO:0070848 39 0.693
Mouse
tissue regeneration GO:0042246 74 0.690
unidimensional cell growth GO:0009826 5 0.686
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.685
Zebrafish
glomerulus vasculature development GO:0072012 2 0.684
larval development GO:0002164 2 0.682
negative regulation of sequestering of calcium ion GO:0051283 4 0.681
hematopoietic or lymphoid organ development GO:0048534 191 0.679
Zebrafish Mouse
cardiac atrium development GO:0003230 4 0.679
neuromast development GO:0048884 46 0.678
positive regulation of neuron apoptotic process GO:0043525 1 0.677
appendage morphogenesis GO:0035107 56 0.676
Zebrafish
positive regulation of transcription dna templated GO:0045893 57 0.674
Zebrafish Mouse Fly
cardiac endothelial cell differentiation GO:0003348 5 0.671
generation of neurons GO:0048699 385 0.668
Zebrafish
cranial nerve development GO:0021545 42 0.667
Zebrafish Mouse
regulation of axon extension involved in axon guidance GO:0048841 6 0.667
mesodermal cell differentiation GO:0048333 21 0.664
post anal tail morphogenesis GO:0036342 19 0.659
Zebrafish
spinal cord patterning GO:0021511 6 0.656
regulation of macromolecule biosynthetic process GO:0010556 225 0.653
Zebrafish Mouse Fly
mesenchymal cell proliferation GO:0010463 1 0.652
Mouse
embryonic hemopoiesis GO:0035162 53 0.651
Zebrafish
cellular biosynthetic process GO:0044249 286 0.648
Zebrafish Mouse Fly
cell fate determination GO:0001709 7 0.644
formation of primary germ layer GO:0001704 62 0.640
Zebrafish
cardioblast differentiation GO:0010002 9 0.640
eye development GO:0001654 277 0.636
Zebrafish
cardiac muscle cell differentiation GO:0055007 30 0.636
positive regulation of cellular process GO:0048522 201 0.634
striated muscle cell proliferation GO:0014855 7 0.634
negative regulation of neurogenesis GO:0050768 20 0.629
axon extension GO:0048675 45 0.625
cell projection organization GO:0030030 284 0.624
neuron projection extension GO:1990138 45 0.620
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.619
determination of left right asymmetry in nervous system GO:0035545 4 0.618
arterial endothelial cell differentiation GO:0060842 2 0.616
common bile duct development GO:0061009 13 0.615
eye morphogenesis GO:0048592 144 0.608
Zebrafish
endodermal cell fate commitment GO:0001711 18 0.605
Zebrafish
cellular nitrogen compound biosynthetic process GO:0044271 218 0.602
Zebrafish Mouse Fly
negative regulation of cellular process GO:0048523 283 0.601
Zebrafish Mouse
regulation of cell death GO:0010941 103 0.594
Mouse
negative regulation of biological process GO:0048519 304 0.592
Zebrafish Mouse
axon extension involved in axon guidance GO:0048846 10 0.591
cell differentiation involved in kidney development GO:0061005 13 0.590
canonical wnt signaling pathway GO:0060070 48 0.585
regulation of cellular component movement GO:0051270 55 0.584
fin development GO:0033333 77 0.581
Zebrafish
sequestering of calcium ion GO:0051208 3 0.580
endothelium development GO:0003158 25 0.580
nephron morphogenesis GO:0072028 2 0.575
anterior posterior pattern specification GO:0009952 152 0.571
Zebrafish Mouse
regulation of behavior GO:0050795 24 0.571
actin filament based process GO:0030029 64 0.569
ventral midline development GO:0007418 13 0.564
determination of dorsal ventral asymmetry GO:0048262 34 0.562
Zebrafish
negative regulation of catabolic process GO:0009895 3 0.557
endothelial cell fate commitment GO:0060839 3 0.552
digestive tract morphogenesis GO:0048546 231 0.550
Zebrafish
hindbrain development GO:0030902 91 0.547
regulation of protein targeting GO:1903533 2 0.547
convergent extension GO:0060026 118 0.545
Zebrafish
neural plate morphogenesis GO:0001839 7 0.544
cerebellum morphogenesis GO:0021587 10 0.538
vestibular receptor cell development GO:0060118 3 0.531
thrombocyte differentiation GO:0002574 4 0.530
heart rudiment development GO:0003313 8 0.520
negative regulation of wnt signaling pathway GO:0030178 30 0.519
regulation of protein localization to nucleus GO:1900180 2 0.516
heart growth GO:0060419 7 0.514
system process GO:0003008 185 0.513
Zebrafish Mouse
maintenance of location GO:0051235 4 0.510
developmental induction GO:0031128 10 0.510
heterocycle biosynthetic process GO:0018130 215 0.510
Zebrafish Mouse Fly
pericardium development GO:0060039 1 0.509
Zebrafish
heart valve development GO:0003170 14 0.507
Zebrafish
axis elongation GO:0003401 31 0.502
Zebrafish
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 9 0.499
regulation of glial cell differentiation GO:0045685 4 0.498
septum transversum development GO:0003343 4 0.497
Zebrafish
cellular response to growth factor stimulus GO:0071363 39 0.497
Mouse
muscle tissue morphogenesis GO:0060415 7 0.496
Mouse
embryonic appendage morphogenesis GO:0035113 30 0.496
Zebrafish
regulation of wnt signaling pathway GO:0030111 53 0.492
cell fate specification GO:0001708 68 0.491
Zebrafish Mouse
muscle organ development GO:0007517 101 0.490
negative regulation of transcription dna templated GO:0045892 45 0.489
Zebrafish Mouse
ameboidal type cell migration GO:0001667 143 0.487
establishment of localization GO:0051234 244 0.483
negative regulation of biosynthetic process GO:0009890 55 0.482
Zebrafish Mouse
muscle organ morphogenesis GO:0048644 8 0.479
Mouse
skeletal system morphogenesis GO:0048705 102 0.479
Mouse
camera type eye development GO:0043010 222 0.478
Zebrafish
establishment of protein localization to organelle GO:0072594 4 0.477
liver morphogenesis GO:0072576 8 0.476
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.471
Zebrafish Mouse Fly
endocardial cell differentiation GO:0060956 5 0.471
positive regulation of multicellular organismal process GO:0051240 52 0.467
Mouse
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.465
regulation of biosynthetic process GO:0009889 250 0.464
Zebrafish Mouse Fly
regulation of axon extension GO:0030516 24 0.462
regulation of cardiac muscle cell differentiation GO:2000725 1 0.460
fin regeneration GO:0031101 51 0.460
foregut morphogenesis GO:0007440 4 0.450
cartilage morphogenesis GO:0060536 13 0.450
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.450
Zebrafish Mouse Fly
sensory system development GO:0048880 76 0.449
positive regulation of signaling GO:0023056 56 0.447
Mouse
axonogenesis GO:0007409 152 0.437
positive regulation of signal transduction GO:0009967 56 0.436
Mouse
wnt signaling pathway calcium modulating pathway GO:0007223 5 0.435
negative regulation of striated muscle tissue development GO:0045843 2 0.435
meiotic chromosome segregation GO:0045132 3 0.433
axis specification GO:0009798 43 0.432
response to bacterium GO:0009617 58 0.431
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.430
positive regulation of nucleic acid templated transcription GO:1903508 57 0.429
Zebrafish Mouse Fly
myeloid cell differentiation GO:0030099 86 0.428
Zebrafish
erythrocyte differentiation GO:0030218 54 0.426
Zebrafish
establishment of cell polarity GO:0030010 18 0.426
spinal cord motor neuron differentiation GO:0021522 26 0.426
Zebrafish
protein targeting to nucleus GO:0044744 3 0.425
regulation of metabolic process GO:0019222 359 0.423
Zebrafish Mouse Fly
medial fin development GO:0033338 16 0.421
response to external biotic stimulus GO:0043207 97 0.421
neuron fate specification GO:0048665 20 0.421
Zebrafish
positive regulation of rna biosynthetic process GO:1902680 57 0.420
Zebrafish Mouse Fly
regulation of protein import into nucleus GO:0042306 2 0.418
cellular response to endogenous stimulus GO:0071495 68 0.415
Mouse
multi organism process GO:0051704 134 0.413
Mouse
tube closure GO:0060606 1 0.410
cell migration to the midline involved in heart development GO:0003318 12 0.409
type b pancreatic cell development GO:0003323 4 0.409
regulation of response to external stimulus GO:0032101 31 0.408
bmp signaling pathway GO:0030509 52 0.403
Zebrafish
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.402
calcium ion transport into cytosol GO:0060402 3 0.401
blastoderm segmentation GO:0007350 6 0.401
cytosolic calcium ion transport GO:0060401 3 0.394
regulation of response to stimulus GO:0048583 269 0.393
Zebrafish Mouse
regulation of nervous system development GO:0051960 90 0.392
g protein coupled receptor signaling pathway GO:0007186 74 0.391
semicircular canal development GO:0060872 24 0.390
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.389
ossification GO:0001503 23 0.387
skeletal muscle tissue development GO:0007519 67 0.387
Mouse
regulation of cell fate specification GO:0042659 20 0.384
regulation of nucleocytoplasmic transport GO:0046822 2 0.379
cell division GO:0051301 20 0.377
regulation of cellular response to growth factor stimulus GO:0090287 35 0.375
regulation of sequestering of calcium ion GO:0051282 4 0.374
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.371
Zebrafish Mouse
positive regulation of glial cell differentiation GO:0045687 1 0.368
regulation of intracellular protein transport GO:0033157 3 0.367
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.366
defense response to other organism GO:0098542 33 0.365
morphogenesis of embryonic epithelium GO:0016331 30 0.360
positive regulation of biosynthetic process GO:0009891 68 0.357
Zebrafish Mouse Fly
macromolecule biosynthetic process GO:0009059 227 0.356
Zebrafish Mouse Fly
positive regulation of cell death GO:0010942 29 0.352
positive regulation of biological process GO:0048518 253 0.350
spemann organizer formation GO:0060061 10 0.350
endodermal digestive tract morphogenesis GO:0061031 2 0.349
neuron projection regeneration GO:0031102 16 0.349
meiotic nuclear division GO:0007126 4 0.348
cardioblast migration to the midline involved in heart field formation GO:0060975 7 0.346
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.344
transcription from rna polymerase ii promoter GO:0006366 80 0.343
Zebrafish Mouse Fly
kidney morphogenesis GO:0060993 15 0.340
Zebrafish
regulation of cell differentiation GO:0045595 142 0.340
Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.338
Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.336
Zebrafish Mouse Fly
single organism nuclear import GO:1902593 3 0.336
dorsal ventral neural tube patterning GO:0021904 1 0.335
neural crest cell development GO:0014032 62 0.335
trabecula morphogenesis GO:0061383 2 0.333
chemotaxis GO:0006935 104 0.333

tbx1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org