Danio rerio

0 known processes

tbx18

T-box 18

tbx18 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
heterocycle biosynthetic process GO:0018130 215 0.988
Zebrafish Mouse
heart morphogenesis GO:0003007 156 0.977
Zebrafish
cellular biosynthetic process GO:0044249 286 0.972
Zebrafish Mouse
heart development GO:0007507 313 0.958
Zebrafish Mouse
rna biosynthetic process GO:0032774 181 0.930
Zebrafish Mouse
regulation of nucleic acid templated transcription GO:1903506 213 0.929
Zebrafish Mouse
digestive tract development GO:0048565 265 0.924
Zebrafish
embryonic organ development GO:0048568 381 0.922
Zebrafish Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.914
Zebrafish Mouse
pericardium morphogenesis GO:0003344 1 0.913
Zebrafish
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.901
Zebrafish
nucleic acid templated transcription GO:0097659 181 0.892
Zebrafish Mouse
regulation of primary metabolic process GO:0080090 311 0.891
Zebrafish Mouse
appendage development GO:0048736 80 0.886
Zebrafish
heart contraction GO:0060047 71 0.883
Zebrafish
embryonic limb morphogenesis GO:0030326 2 0.882
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.877
Zebrafish Mouse
regulation of nitrogen compound metabolic process GO:0051171 251 0.861
Zebrafish Mouse
regulation of multicellular organismal development GO:2000026 223 0.858
Zebrafish Mouse
regulation of transcription dna templated GO:0006355 213 0.854
Zebrafish Mouse
bmp signaling pathway involved in determination of left right symmetry GO:0003154 14 0.848
Zebrafish
determination of bilateral symmetry GO:0009855 204 0.847
Zebrafish
aromatic compound biosynthetic process GO:0019438 217 0.843
Zebrafish Mouse
positive regulation of cellular process GO:0048522 201 0.842
Zebrafish Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.840
Zebrafish Mouse
regulation of rna biosynthetic process GO:2001141 213 0.836
Zebrafish Mouse
muscle tissue development GO:0060537 110 0.829
Zebrafish Mouse
tube morphogenesis GO:0035239 349 0.827
Zebrafish
organic cyclic compound metabolic process GO:1901360 301 0.823
Zebrafish Mouse
camera type eye development GO:0043010 222 0.820
Zebrafish
nucleobase containing compound biosynthetic process GO:0034654 205 0.819
Zebrafish Mouse
neuron development GO:0048666 262 0.805
Zebrafish
muscle structure development GO:0061061 196 0.804
Zebrafish Mouse
regulation of gene expression GO:0010468 265 0.801
Zebrafish Mouse
retina development in camera type eye GO:0060041 146 0.797
Zebrafish
limb bud formation GO:0060174 2 0.787
Zebrafish
regulation of metabolic process GO:0019222 359 0.780
Zebrafish Mouse
cellular component morphogenesis GO:0032989 336 0.767
Zebrafish
organic substance biosynthetic process GO:1901576 289 0.758
Zebrafish Mouse
invagination involved in gastrulation with mouth forming second GO:0055109 1 0.755
Zebrafish
bmp signaling pathway involved in heart jogging GO:0003303 14 0.749
Zebrafish
regulation of multicellular organismal process GO:0051239 277 0.746
Zebrafish Mouse
macromolecule biosynthetic process GO:0009059 227 0.738
Zebrafish Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.734
Zebrafish Mouse
rna metabolic process GO:0016070 219 0.730
Zebrafish Mouse
neuron projection regeneration GO:0031102 16 0.721
skeletal system development GO:0001501 181 0.720
Zebrafish
regulation of macromolecule metabolic process GO:0060255 317 0.715
Zebrafish Mouse
atrioventricular valve formation GO:0003190 3 0.707
Zebrafish
biosynthetic process GO:0009058 294 0.706
Zebrafish Mouse
cellular macromolecule biosynthetic process GO:0034645 224 0.689
Zebrafish Mouse
striated muscle tissue development GO:0014706 110 0.688
Zebrafish Mouse
embryonic skeletal joint development GO:0072498 3 0.688
cell projection organization GO:0030030 284 0.676
organic cyclic compound biosynthetic process GO:1901362 223 0.672
Zebrafish Mouse
regulation of developmental process GO:0050793 247 0.672
Zebrafish Mouse
heterocycle metabolic process GO:0046483 290 0.664
Zebrafish Mouse
heart process GO:0003015 71 0.663
Zebrafish
muscle cell differentiation GO:0042692 139 0.663
Zebrafish Mouse
regulation of rna metabolic process GO:0051252 224 0.662
Zebrafish Mouse
sensory organ development GO:0007423 393 0.654
Zebrafish Mouse
sensory organ morphogenesis GO:0090596 200 0.652
Zebrafish Mouse
cellular macromolecule metabolic process GO:0044260 391 0.648
Zebrafish Mouse
positive regulation of cellular biosynthetic process GO:0031328 68 0.643
Zebrafish
bmp signaling pathway involved in heart development GO:0061312 15 0.637
Zebrafish
nephron epithelium morphogenesis GO:0072088 1 0.631
single organism metabolic process GO:0044710 217 0.627
cell part morphogenesis GO:0032990 246 0.607
cardiac muscle cell differentiation GO:0055007 30 0.601
Zebrafish
heart jogging GO:0003146 40 0.594
Zebrafish
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.592
Zebrafish
cell surface receptor signaling pathway GO:0007166 325 0.590
Zebrafish Mouse
determination of left right symmetry GO:0007368 179 0.588
Zebrafish
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 15 0.587
Zebrafish
fin development GO:0033333 77 0.569
Zebrafish
striated muscle cell differentiation GO:0051146 129 0.569
Zebrafish
regulation of blood circulation GO:1903522 32 0.568
Zebrafish
nitrogen compound metabolic process GO:0006807 319 0.564
Zebrafish Mouse
eye development GO:0001654 277 0.563
Zebrafish
cell morphogenesis involved in differentiation GO:0000904 195 0.555
Zebrafish
morphogenesis of an epithelium GO:0002009 333 0.539
Zebrafish Mouse
specification of symmetry GO:0009799 204 0.536
Zebrafish
mesoderm development GO:0007498 88 0.536
Zebrafish
regeneration GO:0031099 91 0.528
regulation of biosynthetic process GO:0009889 250 0.523
Zebrafish Mouse
cardiac muscle tissue development GO:0048738 48 0.522
Zebrafish Mouse
negative regulation of gene expression GO:0010629 65 0.515
Zebrafish Mouse
signal transduction GO:0007165 455 0.508
Zebrafish Mouse
generation of neurons GO:0048699 385 0.502
Zebrafish
regulation of biological quality GO:0065008 263 0.499
Zebrafish
response to stress GO:0006950 263 0.499
pericardium development GO:0060039 1 0.494
Zebrafish
specification of organ identity GO:0010092 2 0.480
cellular response to organic substance GO:0071310 105 0.471
endocardial cushion formation GO:0003272 2 0.468
embryonic heart tube development GO:0035050 133 0.452
Zebrafish
regionalization GO:0003002 274 0.450
Zebrafish Mouse
cardiocyte differentiation GO:0035051 44 0.448
Zebrafish
blood circulation GO:0008015 87 0.447
Zebrafish
cell motility GO:0048870 244 0.447
Zebrafish
homeostatic process GO:0042592 142 0.441
Zebrafish
nucleic acid metabolic process GO:0090304 244 0.439
Zebrafish Mouse
digestive tract morphogenesis GO:0048546 231 0.423
Zebrafish
epithalamus development GO:0021538 10 0.414
Zebrafish
nephron tubule morphogenesis GO:0072078 1 0.408
embryonic skeletal system morphogenesis GO:0048704 93 0.402
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.395
Zebrafish
determination of heart left right asymmetry GO:0061371 117 0.394
Zebrafish
negative regulation of metabolic process GO:0009892 86 0.392
Zebrafish Mouse
embryonic appendage morphogenesis GO:0035113 30 0.392
Zebrafish
positive regulation of biological process GO:0048518 253 0.391
Zebrafish Mouse
regulation of macromolecule biosynthetic process GO:0010556 225 0.382
Zebrafish Mouse
formation of primary germ layer GO:0001704 62 0.375
Zebrafish
appendage morphogenesis GO:0035107 56 0.371
Zebrafish
regulation of system process GO:0044057 40 0.363
Zebrafish
embryonic organ morphogenesis GO:0048562 274 0.363
Zebrafish Mouse
neuron differentiation GO:0030182 353 0.355
Zebrafish
limb morphogenesis GO:0035108 7 0.354
Zebrafish
negative regulation of biological process GO:0048519 304 0.353
Zebrafish Mouse
myotube differentiation GO:0014902 45 0.351
embryo development ending in birth or egg hatching GO:0009792 271 0.349
Zebrafish Mouse
gene expression GO:0010467 252 0.347
Zebrafish Mouse
epithelial tube morphogenesis GO:0060562 148 0.346
Zebrafish
renal tubule morphogenesis GO:0061333 1 0.345
somitogenesis GO:0001756 87 0.335
Zebrafish Mouse
mesodermal cell fate commitment GO:0001710 14 0.332
cell fate commitment GO:0045165 99 0.327
Zebrafish
enzyme linked receptor protein signaling pathway GO:0007167 106 0.315
Zebrafish
skeletal system morphogenesis GO:0048705 102 0.315
cellular response to endogenous stimulus GO:0071495 68 0.307
artery morphogenesis GO:0048844 14 0.305
cell cell signaling involved in cell fate commitment GO:0045168 12 0.298
cellular nitrogen compound metabolic process GO:0034641 290 0.298
Zebrafish Mouse
axonogenesis GO:0007409 152 0.294
regulation of heart contraction GO:0008016 32 0.287
Zebrafish
behavior GO:0007610 74 0.285
locomotion GO:0040011 313 0.281
Zebrafish
developmental growth GO:0048589 166 0.280
Zebrafish
muscle organ development GO:0007517 101 0.280
Zebrafish
immune system process GO:0002376 241 0.279
Zebrafish
positive regulation of rna metabolic process GO:0051254 59 0.274
Zebrafish
neuron projection morphogenesis GO:0048812 161 0.273
positive regulation of rna biosynthetic process GO:1902680 57 0.271
Zebrafish
embryonic heart tube morphogenesis GO:0003143 108 0.270
Zebrafish
atrial ventricular junction remodeling GO:0003294 2 0.269
Zebrafish
system process GO:0003008 185 0.268
Zebrafish Mouse
neural retina development GO:0003407 49 0.267
Zebrafish
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.265
Zebrafish
ear development GO:0043583 127 0.265
Zebrafish Mouse
transcription from rna polymerase ii promoter GO:0006366 80 0.263
Zebrafish Mouse
craniofacial suture morphogenesis GO:0097094 2 0.263
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.261
Zebrafish
hematopoietic or lymphoid organ development GO:0048534 191 0.260
Zebrafish
hemopoiesis GO:0030097 183 0.255
Zebrafish
mesodermal cell fate specification GO:0007501 12 0.254
cellular nitrogen compound biosynthetic process GO:0044271 218 0.251
Zebrafish Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.251
Zebrafish
regulation of signal transduction GO:0009966 225 0.249
Zebrafish Mouse
regulation of organ morphogenesis GO:2000027 35 0.249
Zebrafish
mesodermal cell differentiation GO:0048333 21 0.248
artery development GO:0060840 22 0.248
pharyngeal muscle development GO:0043282 4 0.248
Zebrafish
specification of organ position GO:0010159 3 0.246
Zebrafish
heart looping GO:0001947 94 0.244
Zebrafish
septum transversum development GO:0003343 4 0.243
Zebrafish
organelle organization GO:0006996 227 0.241
blood vessel morphogenesis GO:0048514 216 0.241
Zebrafish
single organism organelle organization GO:1902589 199 0.239
cellular component movement GO:0006928 335 0.234
Zebrafish
embryonic skeletal system development GO:0048706 97 0.234
positive regulation of transcription dna templated GO:0045893 57 0.234
Zebrafish
anterior posterior pattern specification GO:0009952 152 0.234
Zebrafish Mouse
cell fate specification GO:0001708 68 0.233
Zebrafish
chordate embryonic development GO:0043009 271 0.233
Zebrafish Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.229
Zebrafish Mouse
endocardial cushion morphogenesis GO:0003203 3 0.227
embryonic skeletal joint morphogenesis GO:0060272 3 0.225
positive regulation of biosynthetic process GO:0009891 68 0.224
Zebrafish
auditory receptor cell fate commitment GO:0009912 4 0.221
developmental induction GO:0031128 10 0.219
positive regulation of striated muscle tissue development GO:0045844 1 0.217
apoptotic process GO:0006915 116 0.214
negative regulation of cellular process GO:0048523 283 0.214
Zebrafish Mouse
morphogenesis of an epithelial fold GO:0060571 1 0.214
Zebrafish
bmp signaling pathway GO:0030509 52 0.208
Zebrafish
cardiogenic plate morphogenesis GO:0003142 1 0.205
cell morphogenesis GO:0000902 289 0.204
Zebrafish
positive regulation of macromolecule metabolic process GO:0010604 93 0.200
Zebrafish
regulation of anatomical structure morphogenesis GO:0022603 130 0.194
Zebrafish Mouse
endocardium morphogenesis GO:0003160 4 0.192
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.191
regulation of cellular component organization GO:0051128 86 0.188
pectoral fin development GO:0033339 50 0.187
Zebrafish
striated muscle cell development GO:0055002 108 0.186
positive regulation of nucleic acid templated transcription GO:1903508 57 0.185
Zebrafish
cardiac atrium morphogenesis GO:0003209 2 0.184
response to chemical GO:0042221 320 0.181
angiogenesis GO:0001525 158 0.180
Zebrafish
dorsal ventral pattern formation GO:0009953 125 0.179
Zebrafish
camera type eye morphogenesis GO:0048593 108 0.179
Zebrafish
mesodermal cell migration GO:0008078 12 0.178
transcription dna templated GO:0006351 181 0.177
Zebrafish Mouse
cardiac chamber development GO:0003205 19 0.176
Zebrafish
positive regulation of developmental process GO:0051094 50 0.176
Mouse
positive regulation of muscle organ development GO:0048636 1 0.173
skeletal muscle fiber development GO:0048741 35 0.173
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.170
regulation of chondrocyte differentiation GO:0032330 1 0.165
localization of cell GO:0051674 244 0.165
Zebrafish
outflow tract morphogenesis GO:0003151 1 0.164
negative regulation of response to stimulus GO:0048585 104 0.164
Mouse
positive regulation of metabolic process GO:0009893 108 0.164
Zebrafish
cranial suture morphogenesis GO:0060363 1 0.163
gastrulation GO:0007369 208 0.162
Zebrafish
cardiac cell development GO:0055006 21 0.159
endothelial cell fate commitment GO:0060839 3 0.159
epithelial cell differentiation GO:0030855 116 0.158
olfactory lobe development GO:0021988 4 0.156
cell proliferation involved in heart morphogenesis GO:0061323 2 0.153
Zebrafish
regulation of cell differentiation GO:0045595 142 0.152
heart valve morphogenesis GO:0003179 8 0.152
Zebrafish
tissue remodeling GO:0048771 4 0.149
Zebrafish
neuron projection development GO:0031175 180 0.146
atrioventricular valve morphogenesis GO:0003181 6 0.146
Zebrafish
multicellular organismal metabolic process GO:0044236 2 0.146
homeostasis of number of cells GO:0048872 62 0.146
Zebrafish
muscle cell development GO:0055001 115 0.144
taxis GO:0042330 109 0.144
cell projection morphogenesis GO:0048858 244 0.143
negative regulation of rna biosynthetic process GO:1902679 45 0.142
Zebrafish Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.141
Zebrafish Mouse
glomerulus vasculature development GO:0072012 2 0.139
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.136
regulation of response to nutrient levels GO:0032107 1 0.135
limb development GO:0060173 8 0.134
Zebrafish
heart valve formation GO:0003188 4 0.133
Zebrafish
sprouting angiogenesis GO:0002040 53 0.131
olfactory bulb development GO:0021772 4 0.128
cell cycle GO:0007049 93 0.127
eye morphogenesis GO:0048592 144 0.126
Zebrafish
habenula development GO:0021986 9 0.125
regulation of cellular metabolic process GO:0031323 320 0.121
Zebrafish Mouse
cellular response to growth factor stimulus GO:0071363 39 0.121
regulation of organ growth GO:0046620 3 0.121
regulation of multicellular organism growth GO:0040014 4 0.120
neural tube development GO:0021915 62 0.120
regulation of heart growth GO:0060420 2 0.119
positive regulation of endothelial cell differentiation GO:0045603 2 0.118
muscle cell fate determination GO:0007521 1 0.118
positive regulation of multicellular organismal process GO:0051240 52 0.117
Mouse
positive regulation of gene expression GO:0010628 71 0.115
Zebrafish
apoptotic process involved in development GO:1902742 2 0.114
axon guidance GO:0007411 86 0.111
regulation of bone mineralization GO:0030500 2 0.110
cartilage development GO:0051216 96 0.108
Zebrafish
cardiac muscle tissue morphogenesis GO:0055008 7 0.108
inner ear receptor cell fate commitment GO:0060120 4 0.107
regulation of skeletal muscle tissue development GO:0048641 4 0.107
reproductive process GO:0022414 40 0.107
negative regulation of muscle tissue development GO:1901862 2 0.106
peripheral nervous system neuron differentiation GO:0048934 28 0.106
regulation of cellular ketone metabolic process GO:0010565 7 0.105
negative regulation of developmental process GO:0051093 65 0.104
Mouse
cellular response to chemical stimulus GO:0070887 157 0.102
nephron morphogenesis GO:0072028 2 0.101
segmentation GO:0035282 97 0.101
Zebrafish Mouse
regulation of cell communication GO:0010646 232 0.101
Zebrafish Mouse
nephron development GO:0072006 31 0.100
single organism reproductive process GO:0044702 40 0.100
semicircular canal formation GO:0060876 4 0.099
notochord development GO:0030903 54 0.099
Zebrafish
hematopoietic stem cell differentiation GO:0060218 20 0.098
Zebrafish
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.097
Zebrafish
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.096
somite development GO:0061053 96 0.096
Zebrafish Mouse
positive regulation of muscle tissue development GO:1901863 1 0.096
heart valve development GO:0003170 14 0.095
Zebrafish
developmental growth involved in morphogenesis GO:0060560 86 0.095
Zebrafish
endocardial cushion development GO:0003197 6 0.094
developmental process involved in reproduction GO:0003006 27 0.094
regulation of cell proliferation GO:0042127 37 0.094
Zebrafish Mouse
negative regulation of macromolecule metabolic process GO:0010605 76 0.093
Zebrafish Mouse
regulation of muscle contraction GO:0006937 3 0.093
regulation of cardiac muscle tissue development GO:0055024 1 0.092
positive regulation of cell differentiation GO:0045597 30 0.092
intermediate mesoderm development GO:0048389 2 0.092
Zebrafish
establishment of localization in cell GO:0051649 77 0.091
reproduction GO:0000003 40 0.091
heart field specification GO:0003128 1 0.090
cardiac ventricle development GO:0003231 9 0.090
response to axon injury GO:0048678 14 0.089
regulation of cell fate commitment GO:0010453 22 0.089
cell cell signaling GO:0007267 52 0.089
digestive system development GO:0055123 289 0.088
Zebrafish
response to wounding GO:0009611 116 0.088
negative regulation of multicellular organismal process GO:0051241 69 0.087
Mouse
epithelial cell fate commitment GO:0072148 11 0.087
endocardium development GO:0003157 9 0.086
cardiac muscle cell development GO:0055013 20 0.086
response to hormone GO:0009725 48 0.085
blood vessel development GO:0001568 246 0.085
Zebrafish
response to organic substance GO:0010033 153 0.084
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.083
Zebrafish
response to growth factor GO:0070848 39 0.083
regulation of skeletal muscle fiber development GO:0048742 2 0.083
cardiac ventricle formation GO:0003211 1 0.083
auditory receptor cell fate determination GO:0042668 2 0.082
axon regeneration GO:0031103 14 0.082
connective tissue development GO:0061448 99 0.082
Zebrafish
cellular response to hormone stimulus GO:0032870 39 0.082
response to endogenous stimulus GO:0009719 83 0.082
negative regulation of epithelial cell migration GO:0010633 1 0.080
circulatory system process GO:0003013 87 0.080
Zebrafish
regulation of stem cell differentiation GO:2000736 4 0.080
vasculature development GO:0001944 278 0.079
Zebrafish
primary neural tube formation GO:0014020 1 0.079
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.079
kidney epithelium development GO:0072073 23 0.079
Zebrafish
multi organism process GO:0051704 134 0.079
mesoderm morphogenesis GO:0048332 51 0.079
Zebrafish
axon development GO:0061564 166 0.077
regulation of neurogenesis GO:0050767 87 0.077
neuron fate specification GO:0048665 20 0.077
Zebrafish
multi organism reproductive process GO:0044703 36 0.076
pharyngeal system development GO:0060037 18 0.074
Zebrafish
cellular response to stress GO:0033554 62 0.074
negative regulation of signal transduction GO:0009968 94 0.073
Mouse
cardiac cell fate commitment GO:0060911 1 0.072
central nervous system development GO:0007417 387 0.072
Zebrafish
calcium ion homeostasis GO:0055074 19 0.072
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.072
Mouse
compound eye development GO:0048749 2 0.072
renal tubule development GO:0061326 5 0.071
negative regulation of cell fate specification GO:0009996 11 0.070
proepicardium development GO:0003342 4 0.069
Zebrafish
embryonic cranial skeleton morphogenesis GO:0048701 90 0.069
apoptotic process involved in morphogenesis GO:0060561 2 0.069
programmed cell death GO:0012501 119 0.068
neuron projection guidance GO:0097485 86 0.068
sequestering of metal ion GO:0051238 3 0.068
ion homeostasis GO:0050801 41 0.068
negative regulation of cellular metabolic process GO:0031324 77 0.068
Zebrafish Mouse
growth GO:0040007 174 0.068
Zebrafish
mesoderm formation GO:0001707 43 0.067
Zebrafish
single organism behavior GO:0044708 24 0.067
cell migration GO:0016477 237 0.067
Zebrafish
epithelial to mesenchymal transition GO:0001837 21 0.066
Zebrafish
regulation of apoptotic process GO:0042981 98 0.066
single organismal cell cell adhesion GO:0016337 29 0.065
Mouse
establishment of localization GO:0051234 244 0.065
cellular response to hypoxia GO:0071456 1 0.064
inner ear development GO:0048839 126 0.063
Zebrafish Mouse
regulation of response to stimulus GO:0048583 269 0.063
Zebrafish Mouse
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.063
Zebrafish
negative regulation of striated muscle tissue development GO:0045843 2 0.062
phosphorus metabolic process GO:0006793 109 0.061
negative regulation of cell communication GO:0010648 96 0.061
Mouse
sensory perception GO:0007600 39 0.061
Mouse
negative regulation of endodermal cell differentiation GO:1903225 8 0.060
regulation of protein complex assembly GO:0043254 3 0.060
regulation of receptor mediated endocytosis GO:0048259 4 0.060
regulation of synapse organization GO:0050807 3 0.060
regulation of bmp signaling pathway GO:0030510 39 0.060
Zebrafish
positive regulation of signal transduction GO:0009967 56 0.059
urogenital system development GO:0001655 97 0.058
Zebrafish Mouse
single organism transport GO:0044765 206 0.058
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.058
Zebrafish Mouse
neurological system process GO:0050877 62 0.057
Mouse
somatic muscle development GO:0007525 4 0.057
Zebrafish
multicellular organism reproduction GO:0032504 35 0.056
intracellular signal transduction GO:0035556 85 0.056
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.056
epithelial tube formation GO:0072175 19 0.056
protein modification process GO:0036211 100 0.056
regulation of tube size GO:0035150 2 0.056
mesendoderm development GO:0048382 10 0.055
Zebrafish
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.055
Zebrafish Mouse
proximal distal pattern formation GO:0009954 1 0.055
cardiac conduction system development GO:0003161 1 0.055
Mouse
cell matrix adhesion GO:0007160 4 0.055
stem cell proliferation GO:0072089 4 0.054
Mouse
muscle organ morphogenesis GO:0048644 8 0.054
kupffer s vesicle development GO:0070121 50 0.054
Zebrafish
nephron epithelium development GO:0072009 16 0.054
skeletal muscle organ development GO:0060538 78 0.053
positive regulation of epithelial cell differentiation GO:0030858 2 0.052
positive regulation of cellular metabolic process GO:0031325 94 0.052
Zebrafish
smooth muscle contraction GO:0006939 2 0.051
regulation of synapse assembly GO:0051963 3 0.051
peripheral nervous system neuron development GO:0048935 22 0.051
metal ion homeostasis GO:0055065 26 0.050
atrioventricular valve development GO:0003171 11 0.050
Zebrafish
gamete generation GO:0007276 33 0.050
regulation of cell development GO:0060284 100 0.049
cation homeostasis GO:0055080 33 0.049
neurotransmitter transport GO:0006836 2 0.048
macromolecular complex subunit organization GO:0043933 74 0.048
organ formation GO:0048645 17 0.048
Zebrafish
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.048
gliogenesis GO:0042063 45 0.048
ventricular cardiac muscle tissue development GO:0003229 3 0.047
neuron projection extension GO:1990138 45 0.047
organic acid metabolic process GO:0006082 31 0.047
regulation of reproductive process GO:2000241 4 0.046
cardiac chamber formation GO:0003207 4 0.046
photoreceptor cell fate commitment GO:0046552 1 0.046
Zebrafish
regulation of protein transport GO:0051223 3 0.046
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.046
Zebrafish
spemann organizer formation GO:0060061 10 0.045
nephron tubule development GO:0072080 4 0.045
regulation of mesodermal cell fate specification GO:0042661 9 0.045
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.045
optic placode formation involved in camera type eye formation GO:0046619 3 0.044
multicellular organismal reproductive process GO:0048609 35 0.044
actin filament based process GO:0030029 64 0.044
spinal cord motor neuron differentiation GO:0021522 26 0.044
Zebrafish
negative regulation of cell fate commitment GO:0010454 13 0.044
divalent inorganic cation homeostasis GO:0072507 22 0.043
morphogenesis of embryonic epithelium GO:0016331 30 0.043
Mouse
gland development GO:0048732 143 0.043
regulation of cell death GO:0010941 103 0.043
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.043
Zebrafish Mouse
determination of dorsal identity GO:0048263 13 0.042
Zebrafish
lateral inhibition GO:0046331 1 0.042
somatic stem cell maintenance GO:0035019 1 0.042
positive regulation of cell cycle GO:0045787 3 0.042
muscle fiber development GO:0048747 52 0.042
spinal cord development GO:0021510 46 0.042
Zebrafish
tissue regeneration GO:0042246 74 0.042
embryonic neurocranium morphogenesis GO:0048702 15 0.042
exocrine pancreas development GO:0031017 28 0.042
response to alkaloid GO:0043279 2 0.042
head development GO:0060322 303 0.041
Zebrafish
regulation of transport GO:0051049 45 0.041
post embryonic morphogenesis GO:0009886 4 0.041
regulation of cellular protein metabolic process GO:0032268 52 0.041
positive regulation of cellular component biogenesis GO:0044089 3 0.041
locomotory behavior GO:0007626 34 0.041
rhombomere formation GO:0021594 12 0.041
cell differentiation in spinal cord GO:0021515 40 0.041
Zebrafish
arterial endothelial cell differentiation GO:0060842 2 0.041
positive regulation of cell communication GO:0010647 56 0.041
single organism localization GO:1902578 225 0.040
regulation of biomineral tissue development GO:0070167 2 0.040
cellular cation homeostasis GO:0030003 17 0.039
pronephros development GO:0048793 69 0.039
Zebrafish
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.039
post embryonic organ development GO:0048569 4 0.039
muscle system process GO:0003012 20 0.039
regulation of cell activation GO:0050865 1 0.039
multicellular organism growth GO:0035264 4 0.038
morphogenesis of a branching structure GO:0001763 21 0.038
embryonic epithelial tube formation GO:0001838 17 0.037
erythrocyte homeostasis GO:0034101 55 0.037
Zebrafish
renal system vasculature development GO:0061437 2 0.037
muscle contraction GO:0006936 18 0.037
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.037
lipid storage GO:0019915 1 0.037
single organism intracellular transport GO:1902582 25 0.037
response to oxygen containing compound GO:1901700 55 0.037
negative regulation of heart contraction GO:0045822 2 0.036
retina morphogenesis in camera type eye GO:0060042 79 0.036
Zebrafish
regulation of blood vessel size GO:0050880 2 0.036
positive regulation of transport GO:0051050 2 0.036
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.036
Zebrafish
endocardium formation GO:0060214 1 0.036
maintenance of location GO:0051235 4 0.036
divalent metal ion transport GO:0070838 20 0.036
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.035
neuron fate commitment GO:0048663 26 0.035
Zebrafish
regulation of nervous system development GO:0051960 90 0.035
regulation of endodermal cell fate specification GO:0042663 15 0.035
aorta development GO:0035904 4 0.035
axis elongation GO:0003401 31 0.034
Zebrafish
embryonic heart tube formation GO:0003144 1 0.034
regulation of muscle organ development GO:0048634 9 0.034
regulation of endothelial cell differentiation GO:0045601 3 0.034
convergent extension involved in axis elongation GO:0060028 26 0.034
Zebrafish
positive regulation of cell development GO:0010720 25 0.034
oxidation reduction process GO:0055114 41 0.034
regulation of stem cell proliferation GO:0072091 2 0.033
Mouse
neuron fate determination GO:0048664 2 0.033
brain development GO:0007420 293 0.033
Zebrafish

tbx18 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.389
musculoskeletal system disease DOID:17 0 0.389
muscular disease DOID:0080000 0 0.233
cardiomyopathy DOID:0050700 0 0.233
heart disease DOID:114 0 0.233
cardiovascular system disease DOID:1287 0 0.233
muscle tissue disease DOID:66 0 0.233
myopathy DOID:423 0 0.233
intrinsic cardiomyopathy DOID:0060036 0 0.190
connective tissue disease DOID:65 0 0.118
bone disease DOID:0080001 0 0.118
bone development disease DOID:0080006 0 0.051
physical disorder DOID:0080015 0 0.035