Danio rerio

23 known processes

tbx2a

T-box gene 2a

(Aliases: MGC85705,tbxa,tbx-a,zgc:85705,tbx2l)

tbx2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
heart jogging GO:0003146 40 0.998
Zebrafish
regulation of blood circulation GO:1903522 32 0.985
Zebrafish
heart morphogenesis GO:0003007 156 0.979
Zebrafish Mouse
septum transversum development GO:0003343 4 0.958
Zebrafish
embryonic heart tube morphogenesis GO:0003143 108 0.956
Zebrafish Mouse
regulation of macromolecule biosynthetic process GO:0010556 225 0.939
Zebrafish Mouse Fly
nucleobase containing compound biosynthetic process GO:0034654 205 0.920
Zebrafish Mouse Fly
rna biosynthetic process GO:0032774 181 0.910
Zebrafish Mouse Fly
tissue remodeling GO:0048771 4 0.898
Zebrafish
heart development GO:0007507 313 0.898
heart looping GO:0001947 94 0.894
Zebrafish Mouse
pericardium development GO:0060039 1 0.873
Zebrafish
digestive system development GO:0055123 289 0.861
Zebrafish Mouse Worm
cellular biosynthetic process GO:0044249 286 0.854
Zebrafish Mouse Fly
muscle tissue development GO:0060537 110 0.853
Zebrafish Mouse
hematopoietic stem cell differentiation GO:0060218 20 0.836
Zebrafish
organic substance biosynthetic process GO:1901576 289 0.830
Zebrafish Mouse Fly
biosynthetic process GO:0009058 294 0.811
Zebrafish Mouse Fly
atrial ventricular junction remodeling GO:0003294 2 0.809
Zebrafish
limb bud formation GO:0060174 2 0.807
Zebrafish
eye photoreceptor cell development GO:0042462 30 0.801
Zebrafish
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.782
Zebrafish
embryonic organ development GO:0048568 381 0.763
invagination involved in gastrulation with mouth forming second GO:0055109 1 0.763
Zebrafish
regulation of nucleic acid templated transcription GO:1903506 213 0.760
Zebrafish Mouse Fly
blood vessel morphogenesis GO:0048514 216 0.740
Zebrafish Mouse
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.720
Zebrafish
proepicardium development GO:0003342 4 0.720
Zebrafish
signal transduction GO:0007165 455 0.717
Zebrafish
striated muscle tissue development GO:0014706 110 0.717
Zebrafish Mouse
organic cyclic compound biosynthetic process GO:1901362 223 0.716
Zebrafish Mouse Fly
kidney development GO:0001822 92 0.710
Zebrafish
cellular macromolecule biosynthetic process GO:0034645 224 0.705
Zebrafish Mouse Fly
muscle structure development GO:0061061 196 0.692
Zebrafish Mouse Worm
vasculature development GO:0001944 278 0.691
Zebrafish Mouse
cardiac muscle cell differentiation GO:0055007 30 0.657
Zebrafish
single organism cell adhesion GO:0098602 29 0.657
striated muscle cell differentiation GO:0051146 129 0.644
Zebrafish
retinal rod cell development GO:0046548 4 0.636
Zebrafish
bmp signaling pathway involved in heart jogging GO:0003303 14 0.613
Zebrafish
regulation of primary metabolic process GO:0080090 311 0.612
Zebrafish Mouse Fly
blood vessel development GO:0001568 246 0.608
Zebrafish Mouse
intermediate mesoderm development GO:0048389 2 0.600
Zebrafish
pronephros morphogenesis GO:0072114 14 0.595
Zebrafish
regulation of transcription dna templated GO:0006355 213 0.594
Zebrafish Mouse Fly
positive regulation of macromolecule metabolic process GO:0010604 93 0.589
Zebrafish
cell surface receptor signaling pathway GO:0007166 325 0.587
Zebrafish
determination of dorsal ventral asymmetry GO:0048262 34 0.580
Zebrafish
cellular component movement GO:0006928 335 0.575
Zebrafish
atrioventricular valve formation GO:0003190 3 0.574
Zebrafish
aromatic compound biosynthetic process GO:0019438 217 0.572
Zebrafish Mouse Fly
embryonic organ morphogenesis GO:0048562 274 0.567
Zebrafish Mouse
neuron differentiation GO:0030182 353 0.566
Zebrafish
angiogenesis GO:0001525 158 0.560
Zebrafish
cellular component morphogenesis GO:0032989 336 0.554
Zebrafish
transcription dna templated GO:0006351 181 0.552
Zebrafish Mouse Fly
ameboidal type cell migration GO:0001667 143 0.544
Zebrafish
glomerulus morphogenesis GO:0072102 7 0.536
gastrulation GO:0007369 208 0.514
Zebrafish
regulation of rna biosynthetic process GO:2001141 213 0.513
Zebrafish Mouse Fly
negative regulation of biological process GO:0048519 304 0.507
Zebrafish Mouse Fly
neuron development GO:0048666 262 0.500
Zebrafish
regulation of nitrogen compound metabolic process GO:0051171 251 0.496
Zebrafish Mouse Fly
positive regulation of biological process GO:0048518 253 0.479
Zebrafish Mouse
heart process GO:0003015 71 0.479
Zebrafish
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.476
Zebrafish
negative regulation of cellular biosynthetic process GO:0031327 55 0.473
Zebrafish Mouse Fly
regulation of biosynthetic process GO:0009889 250 0.472
Zebrafish Mouse Fly
negative regulation of biosynthetic process GO:0009890 55 0.469
Zebrafish Mouse Fly
heterocycle biosynthetic process GO:0018130 215 0.468
Zebrafish Mouse Fly
cartilage development GO:0051216 96 0.463
Zebrafish
cardiac conduction system development GO:0003161 1 0.455
specification of symmetry GO:0009799 204 0.449
Zebrafish Mouse
enzyme linked receptor protein signaling pathway GO:0007167 106 0.444
Zebrafish
single organismal cell cell adhesion GO:0016337 29 0.441
regulation of macromolecule metabolic process GO:0060255 317 0.428
Zebrafish Mouse Fly
epithelial cell differentiation GO:0030855 116 0.427
endothelial cell fate commitment GO:0060839 3 0.420
biological adhesion GO:0022610 40 0.414
Zebrafish
atrioventricular valve morphogenesis GO:0003181 6 0.411
Zebrafish
fin morphogenesis GO:0033334 53 0.405
Zebrafish
nucleic acid templated transcription GO:0097659 181 0.398
Zebrafish Mouse Fly
lymphangiogenesis GO:0001946 25 0.392
bmp signaling pathway involved in determination of left right symmetry GO:0003154 14 0.375
Zebrafish
eye photoreceptor cell differentiation GO:0001754 45 0.373
Zebrafish
regionalization GO:0003002 274 0.368
Zebrafish Fly
response to fluid shear stress GO:0034405 2 0.357
morphogenesis of an epithelial fold GO:0060571 1 0.352
Zebrafish
generation of neurons GO:0048699 385 0.351
Zebrafish
pericardium morphogenesis GO:0003344 1 0.348
Zebrafish
embryonic limb morphogenesis GO:0030326 2 0.345
Mouse
negative regulation of cellular process GO:0048523 283 0.331
Zebrafish Mouse Fly
regulation of metabolic process GO:0019222 359 0.329
Zebrafish Mouse Fly
heterocycle metabolic process GO:0046483 290 0.319
Zebrafish Mouse Fly
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 15 0.319
Zebrafish Mouse
mesoderm formation GO:0001707 43 0.313
Zebrafish
endoderm development GO:0007492 49 0.313
Zebrafish
camera type eye development GO:0043010 222 0.311
Zebrafish Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.305
Zebrafish Mouse Fly
determination of bilateral symmetry GO:0009855 204 0.303
Zebrafish Mouse
negative regulation of stem cell differentiation GO:2000737 2 0.302
locomotion GO:0040011 313 0.301
Zebrafish Worm
somatic muscle development GO:0007525 4 0.301
Zebrafish
pharyngeal system development GO:0060037 18 0.298
fin development GO:0033333 77 0.297
Zebrafish
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.297
Zebrafish Mouse Fly
lymph vessel development GO:0001945 27 0.295
cation transport GO:0006812 81 0.294
blood circulation GO:0008015 87 0.293
Zebrafish
cardiac cell fate commitment GO:0060911 1 0.288
photoreceptor cell development GO:0042461 40 0.285
Zebrafish
mesoderm morphogenesis GO:0048332 51 0.284
Zebrafish
specification of organ position GO:0010159 3 0.284
Zebrafish
gene expression GO:0010467 252 0.282
Zebrafish Mouse Fly
retinal cone cell differentiation GO:0042670 12 0.282
Zebrafish
striated muscle cell proliferation GO:0014855 7 0.278
Mouse
determination of dorsal identity GO:0048263 13 0.275
Zebrafish
cranial suture morphogenesis GO:0060363 1 0.274
morphogenesis of an epithelial sheet GO:0002011 49 0.269
Zebrafish
retinal cone cell development GO:0046549 8 0.267
Zebrafish
gastrulation with mouth forming second GO:0001702 44 0.266
Zebrafish
digestive tract development GO:0048565 265 0.262
Zebrafish Mouse Worm
regulation of rna metabolic process GO:0051252 224 0.256
Zebrafish Mouse Fly
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.256
Zebrafish
embryonic heart tube development GO:0035050 133 0.254
atrioventricular valve development GO:0003171 11 0.249
Zebrafish
cell morphogenesis GO:0000902 289 0.246
Zebrafish
regulation of cell development GO:0060284 100 0.241
nephric duct morphogenesis GO:0072178 7 0.239
Zebrafish
urogenital system development GO:0001655 97 0.232
Zebrafish
cell fate commitment GO:0045165 99 0.227
Zebrafish Mouse Worm
organic cyclic compound metabolic process GO:1901360 301 0.226
Zebrafish Mouse Fly
epithelial tube morphogenesis GO:0060562 148 0.226
Zebrafish Mouse
circulatory system process GO:0003013 87 0.225
Zebrafish
cardiac muscle tissue development GO:0048738 48 0.222
Zebrafish Mouse
retina development in camera type eye GO:0060041 146 0.216
Zebrafish
cell adhesion GO:0007155 40 0.214
Zebrafish
neural retina development GO:0003407 49 0.214
Zebrafish
negative regulation of axon guidance GO:1902668 1 0.208
regulation of synapse assembly GO:0051963 3 0.203
dorsal ventral pattern formation GO:0009953 125 0.201
Zebrafish
appendage morphogenesis GO:0035107 56 0.198
Zebrafish Mouse Fly
nucleobase containing compound metabolic process GO:0006139 274 0.195
Zebrafish Mouse Fly
outflow tract morphogenesis GO:0003151 1 0.195
Mouse
glomerulus vasculature development GO:0072012 2 0.195
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.195
inner ear development GO:0048839 126 0.194
Zebrafish
fourth ventricle development GO:0021592 8 0.192
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.192
Zebrafish Mouse Fly
photoreceptor cell fate specification GO:0043704 1 0.183
Zebrafish
regulation of bmp signaling pathway GO:0030510 39 0.182
Zebrafish
regulation of gene expression GO:0010468 265 0.182
Zebrafish Mouse Fly
semicircular canal development GO:0060872 24 0.181
Zebrafish
positive regulation of gene expression GO:0010628 71 0.180
Zebrafish
bmp signaling pathway GO:0030509 52 0.178
Zebrafish
regulation of organ morphogenesis GO:2000027 35 0.176
Zebrafish Mouse
defense response GO:0006952 47 0.175
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.175
Zebrafish Mouse Fly
renal system development GO:0072001 94 0.174
Zebrafish
craniofacial suture morphogenesis GO:0097094 2 0.173
morphogenesis of an epithelium GO:0002009 333 0.170
Zebrafish Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.170
Zebrafish Mouse Fly
connective tissue development GO:0061448 99 0.169
Zebrafish
mesendoderm development GO:0048382 10 0.168
Zebrafish
determination of left right asymmetry in nervous system GO:0035545 4 0.167
notochord development GO:0030903 54 0.160
Zebrafish
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.156
Zebrafish
lymph vessel morphogenesis GO:0036303 25 0.154
regulation of cardiac muscle tissue development GO:0055024 1 0.153
Mouse
negative regulation of macromolecule metabolic process GO:0010605 76 0.151
Zebrafish Mouse Fly
convergent extension GO:0060026 118 0.150
Zebrafish
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.149
Zebrafish
cell projection organization GO:0030030 284 0.149
negative regulation of muscle tissue development GO:1901862 2 0.148
regulation of behavior GO:0050795 24 0.144
bmp signaling pathway involved in heart development GO:0061312 15 0.141
Zebrafish
lymphatic endothelial cell differentiation GO:0060836 1 0.140
ventricular cardiac muscle tissue development GO:0003229 3 0.139
regulation of signaling GO:0023051 235 0.137
Zebrafish
heart field specification GO:0003128 1 0.135
positive regulation of transport GO:0051050 2 0.134
heart formation GO:0060914 13 0.134
Zebrafish
mesenchymal cell proliferation GO:0010463 1 0.133
regulation of cellular biosynthetic process GO:0031326 245 0.133
Zebrafish Mouse Fly
transcription from rna polymerase ii promoter GO:0006366 80 0.132
Zebrafish Mouse Fly
retinal ganglion cell axon guidance GO:0031290 35 0.132
regeneration GO:0031099 91 0.129
regulation of cellular component movement GO:0051270 55 0.128
limb morphogenesis GO:0035108 7 0.127
Zebrafish Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.127
Zebrafish
diencephalon development GO:0021536 58 0.125
Zebrafish
medial fin development GO:0033338 16 0.125
cell fate specification GO:0001708 68 0.124
Zebrafish Worm
cell proliferation involved in heart morphogenesis GO:0061323 2 0.123
Zebrafish
neuron fate specification GO:0048665 20 0.122
Zebrafish
neuron projection extension involved in neuron projection guidance GO:1902284 10 0.121
positive regulation of rna biosynthetic process GO:1902680 57 0.120
Zebrafish
endodermal cell differentiation GO:0035987 19 0.119
Zebrafish
mesenchyme development GO:0060485 127 0.119
Zebrafish Mouse
regulation of system process GO:0044057 40 0.119
Zebrafish
cranial nerve development GO:0021545 42 0.118
Zebrafish
positive regulation of biosynthetic process GO:0009891 68 0.113
Zebrafish
regulation of cellular metabolic process GO:0031323 320 0.113
Zebrafish Mouse Fly
rna metabolic process GO:0016070 219 0.112
Zebrafish Mouse Fly
photoreceptor cell fate commitment GO:0046552 1 0.111
Zebrafish
axon extension GO:0048675 45 0.110
cell migration involved in gastrulation GO:0042074 79 0.109
Zebrafish
regulation of stem cell proliferation GO:0072091 2 0.108
nitrogen compound metabolic process GO:0006807 319 0.108
Zebrafish Mouse Fly
positive regulation of cellular biosynthetic process GO:0031328 68 0.108
Zebrafish
kidney morphogenesis GO:0060993 15 0.107
Zebrafish
regulation of myotube differentiation GO:0010830 2 0.105
neuron projection development GO:0031175 180 0.105
regulation of cell differentiation GO:0045595 142 0.103
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.102
Zebrafish Mouse Fly
divalent metal ion transport GO:0070838 20 0.101
lateral mesoderm development GO:0048368 23 0.100
Zebrafish
specification of organ identity GO:0010092 2 0.100
tube morphogenesis GO:0035239 349 0.099
Zebrafish Mouse
regulation of heart contraction GO:0008016 32 0.098
Zebrafish
regulation of axon guidance GO:1902667 8 0.097
cardiac chamber development GO:0003205 19 0.096
cellular response to stress GO:0033554 62 0.096
regulation of embryonic development GO:0045995 47 0.095
Zebrafish Mouse
neuron projection extension GO:1990138 45 0.094
camera type eye photoreceptor cell differentiation GO:0060219 19 0.094
Zebrafish
eye morphogenesis GO:0048592 144 0.093
Zebrafish Mouse Fly
negative regulation of blood circulation GO:1903523 2 0.093
cardiac chamber formation GO:0003207 4 0.093
Mouse
nucleic acid metabolic process GO:0090304 244 0.093
Zebrafish Mouse Fly
regulation of cell cell adhesion GO:0022407 13 0.092
cell morphogenesis involved in differentiation GO:0000904 195 0.091
Zebrafish
inner ear morphogenesis GO:0042472 63 0.090
Zebrafish
chondrocyte development GO:0002063 4 0.089
heart valve development GO:0003170 14 0.089
Zebrafish
immune system development GO:0002520 191 0.089
Zebrafish
camera type eye morphogenesis GO:0048593 108 0.088
Zebrafish Mouse
chordate embryonic development GO:0043009 271 0.088
dorsal convergence GO:0060030 14 0.087
heart contraction GO:0060047 71 0.087
Zebrafish
pectoral fin morphogenesis GO:0035138 29 0.080
Zebrafish
response to external stimulus GO:0009605 264 0.080
regulation of muscle tissue development GO:1901861 6 0.079
Mouse
synaptic target recognition GO:0008039 1 0.078
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.077
Mouse Fly
regulation of cellular component organization GO:0051128 86 0.076
regulation of response to stimulus GO:0048583 269 0.075
Zebrafish
negative regulation of striated muscle cell differentiation GO:0051154 1 0.075
endodermal cell fate determination GO:0007493 2 0.075
determination of ventral identity GO:0048264 21 0.074
brain development GO:0007420 293 0.071
Zebrafish
stem cell proliferation GO:0072089 4 0.071
response to nutrient GO:0007584 3 0.069
positive regulation of programmed cell death GO:0043068 29 0.069
spinal cord development GO:0021510 46 0.069
Zebrafish
regulation of synapse organization GO:0050807 3 0.069
pronephric duct morphogenesis GO:0039023 7 0.068
Zebrafish
localization of cell GO:0051674 244 0.068
Zebrafish
muscle cell fate determination GO:0007521 1 0.068
Mouse
pectoral fin development GO:0033339 50 0.067
Zebrafish
pharyngeal muscle development GO:0043282 4 0.067
Zebrafish Worm
positive regulation of rna metabolic process GO:0051254 59 0.066
Zebrafish
chemotaxis GO:0006935 104 0.066
single organism organelle organization GO:1902589 199 0.065
kidney vasculature morphogenesis GO:0061439 1 0.064
positive regulation of epithelial cell proliferation GO:0050679 1 0.063
regulation of tube size GO:0035150 2 0.063
regulation of axon extension involved in axon guidance GO:0048841 6 0.061
positive regulation of stem cell proliferation GO:2000648 1 0.061
cellular nitrogen compound metabolic process GO:0034641 290 0.060
Zebrafish Mouse Fly
macromolecule biosynthetic process GO:0009059 227 0.059
Zebrafish Mouse Fly
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.059
Zebrafish Mouse Fly
cardiac ventricle formation GO:0003211 1 0.059
ventral spinal cord development GO:0021517 35 0.058
Zebrafish
developmental growth involved in morphogenesis GO:0060560 86 0.058
Zebrafish Mouse
sensory perception of pain GO:0019233 1 0.058
notochord morphogenesis GO:0048570 17 0.058
heart valve morphogenesis GO:0003179 8 0.058
Zebrafish
cellular ion homeostasis GO:0006873 17 0.058
regulation of muscle organ development GO:0048634 9 0.057
Mouse
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.057
Zebrafish
vascular endothelial growth factor receptor signaling pathway GO:0048010 13 0.056
regulation of epithelial to mesenchymal transition GO:0010717 3 0.056
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.055
regulation of heart morphogenesis GO:2000826 17 0.055
Zebrafish Mouse
cellular component assembly involved in morphogenesis GO:0010927 107 0.053
response to chemical GO:0042221 320 0.053
Worm
growth GO:0040007 174 0.053
Zebrafish Mouse Fly
response to lipid GO:0033993 60 0.051
regulation of cell migration GO:0030334 40 0.051
system process GO:0003008 185 0.051
Zebrafish
vasculogenesis GO:0001570 41 0.051
Zebrafish
negative regulation of striated muscle tissue development GO:0045843 2 0.050
renal system vasculature development GO:0061437 2 0.050
regulation of anatomical structure morphogenesis GO:0022603 130 0.049
Zebrafish Mouse
cellular component biogenesis GO:0044085 178 0.049
cellular homeostasis GO:0019725 26 0.049
female sex differentiation GO:0046660 4 0.048
type b pancreatic cell development GO:0003323 4 0.047
regulation of cell adhesion GO:0030155 15 0.047
positive regulation of cellular component biogenesis GO:0044089 3 0.047
cell part morphogenesis GO:0032990 246 0.046
regulation of axonogenesis GO:0050770 32 0.046
nerve development GO:0021675 45 0.046
Zebrafish
protein localization to nucleus GO:0034504 3 0.045
cellular macromolecule metabolic process GO:0044260 391 0.045
Zebrafish Mouse Fly
muscle cell fate commitment GO:0042693 9 0.044
Mouse Worm
regulation of metal ion transport GO:0010959 4 0.044
positive regulation of muscle tissue development GO:1901863 1 0.044
Mouse
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.044
cellular response to lipopolysaccharide GO:0071222 3 0.043
optomotor response GO:0071632 1 0.043
somitogenesis GO:0001756 87 0.043
Zebrafish
negative regulation of neuron differentiation GO:0045665 10 0.043
regulation of skeletal muscle fiber development GO:0048742 2 0.043
regulation of signal transduction GO:0009966 225 0.042
Zebrafish
convergent extension involved in gastrulation GO:0060027 71 0.042
embryonic appendage morphogenesis GO:0035113 30 0.042
Zebrafish Mouse
gland development GO:0048732 143 0.042
Mouse
cell migration GO:0016477 237 0.042
Zebrafish
cellular component assembly GO:0022607 170 0.041
sprouting angiogenesis GO:0002040 53 0.041
response to radiation GO:0009314 51 0.041
multi organism process GO:0051704 134 0.041
positive regulation of striated muscle tissue development GO:0045844 1 0.041
Mouse
multicellular organismal metabolic process GO:0044236 2 0.040
negative regulation of gene expression GO:0010629 65 0.040
Zebrafish Mouse Fly
endoderm formation GO:0001706 29 0.040
Zebrafish
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.040
Zebrafish
somatic stem cell maintenance GO:0035019 1 0.039
negative regulation of metabolic process GO:0009892 86 0.039
Zebrafish Mouse Fly
innervation GO:0060384 3 0.039
notochord cell differentiation GO:0060034 18 0.039
Zebrafish
mesoderm development GO:0007498 88 0.038
Zebrafish
epithelial cell fate commitment GO:0072148 11 0.038
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.038
digestive tract morphogenesis GO:0048546 231 0.038
Zebrafish
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.038
regulation of locomotion GO:0040012 55 0.038
stem cell differentiation GO:0048863 117 0.038
Zebrafish Mouse
determination of left right asymmetry in lateral mesoderm GO:0003140 20 0.037
Zebrafish
endothelial cell differentiation GO:0045446 20 0.037
muscle cell differentiation GO:0042692 139 0.037
Zebrafish Mouse Worm
cell cell signaling involved in cell fate commitment GO:0045168 12 0.036
sensory organ morphogenesis GO:0090596 200 0.036
Zebrafish Mouse Fly
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.036
negative regulation of rna biosynthetic process GO:1902679 45 0.036
Zebrafish Mouse Fly
cardiocyte differentiation GO:0035051 44 0.036
Zebrafish Mouse
positive regulation of cellular metabolic process GO:0031325 94 0.036
Zebrafish
axon extension involved in axon guidance GO:0048846 10 0.036
limb development GO:0060173 8 0.035
Zebrafish Mouse
cartilage condensation GO:0001502 3 0.035
renal system vasculature morphogenesis GO:0061438 1 0.035
endodermal cell fate commitment GO:0001711 18 0.035
Zebrafish
negative chemotaxis GO:0050919 1 0.035
anterior posterior axon guidance GO:0033564 5 0.035
regulation of chondrocyte differentiation GO:0032330 1 0.035
negative regulation of cell differentiation GO:0045596 46 0.034
cellular response to external stimulus GO:0071496 2 0.034
chondrocyte differentiation GO:0002062 7 0.034
neuron projection morphogenesis GO:0048812 161 0.034
positive regulation of muscle organ development GO:0048636 1 0.033
Mouse
intracellular steroid hormone receptor signaling pathway GO:0030518 5 0.033
cartilage morphogenesis GO:0060536 13 0.033
Zebrafish
left right pattern formation GO:0060972 19 0.033
response to bacterium GO:0009617 58 0.033
negative regulation of cellular metabolic process GO:0031324 77 0.033
Zebrafish Mouse Fly
regulation of neuron projection development GO:0010975 40 0.032
positive regulation of nucleic acid templated transcription GO:1903508 57 0.032
Zebrafish
embryonic neurocranium morphogenesis GO:0048702 15 0.032
determination of left right symmetry GO:0007368 179 0.032
Zebrafish Mouse
negative regulation of chemotaxis GO:0050922 4 0.032
hard palate development GO:0060022 4 0.032
determination of left right asymmetry in diencephalon GO:0035462 4 0.031
cloaca development GO:0035844 9 0.031
Zebrafish
negative regulation of neuron projection development GO:0010977 9 0.030
atrial cardiac muscle cell development GO:0055014 4 0.030
positive regulation of cellular process GO:0048522 201 0.030
Zebrafish Mouse
embryo development ending in birth or egg hatching GO:0009792 271 0.030
organ formation GO:0048645 17 0.030
Zebrafish
regulation of cellular protein metabolic process GO:0032268 52 0.029
regulation of biomineral tissue development GO:0070167 2 0.029
positive regulation of cell proliferation GO:0008284 15 0.029
Zebrafish Mouse
ear development GO:0043583 127 0.029
Zebrafish
atrial cardiac muscle cell differentiation GO:0055011 5 0.029
regulation of localization GO:0032879 104 0.029
Worm
establishment of mitotic spindle localization GO:0040001 12 0.029
glycolipid metabolic process GO:0006664 8 0.028
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.028
viral process GO:0016032 1 0.028
positive regulation of cell cycle GO:0045787 3 0.028
cardiac cell development GO:0055006 21 0.028
larval development GO:0002164 2 0.027
Worm
semicircular canal morphogenesis GO:0048752 18 0.027
Zebrafish
positive regulation of transcription dna templated GO:0045893 57 0.027
Zebrafish
embryonic medial fin morphogenesis GO:0035122 6 0.027
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.027
Zebrafish
response to oxygen levels GO:0070482 25 0.027
retina morphogenesis in camera type eye GO:0060042 79 0.026
Zebrafish
transport GO:0006810 220 0.026
endocrine system development GO:0035270 65 0.026
cellular response to oxygen levels GO:0071453 1 0.026
positive regulation of cell activation GO:0050867 1 0.026
nephron tubule morphogenesis GO:0072078 1 0.026
cardiac atrium development GO:0003230 4 0.026
sulfur compound transport GO:0072348 3 0.026
organelle organization GO:0006996 227 0.026
central nervous system formation GO:0021556 1 0.026
stem cell division GO:0017145 1 0.026
axon guidance GO:0007411 86 0.026
spinal cord motor neuron differentiation GO:0021522 26 0.026
Zebrafish
response to stress GO:0006950 263 0.026
negative regulation of cell morphogenesis involved in differentiation GO:0010771 8 0.025
metal ion transport GO:0030001 58 0.025
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.025
Zebrafish Mouse Fly
pronephric glomerulus morphogenesis GO:0035775 6 0.025
cation homeostasis GO:0055080 33 0.025
positive regulation of apoptotic process GO:0043065 29 0.025
regulation of collagen metabolic process GO:0010712 2 0.024
protein homooligomerization GO:0051260 3 0.024
regulation of proteolysis GO:0030162 24 0.024
dendrite guidance GO:0070983 0 0.024
homeostatic process GO:0042592 142 0.024
Zebrafish
cardiac muscle cell proliferation GO:0060038 5 0.024
Mouse
embryonic camera type eye formation GO:0060900 10 0.023
negative regulation of nuclear division GO:0051784 3 0.023
central nervous system neuron differentiation GO:0021953 74 0.023
Zebrafish
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.023
ion transport GO:0006811 114 0.023
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.023
entrainment of circadian clock GO:0009649 2 0.023
embryonic pectoral fin morphogenesis GO:0035118 24 0.023
Zebrafish
mesenchymal cell differentiation GO:0048762 87 0.023
Zebrafish
gall bladder development GO:0061010 1 0.022
lipid metabolic process GO:0006629 52 0.022
calcium ion homeostasis GO:0055074 19 0.022
lymphocyte proliferation GO:0046651 1 0.022
actin filament based process GO:0030029 64 0.022
mesodermal cell fate commitment GO:0001710 14 0.022
regulation of cell proliferation GO:0042127 37 0.022
Zebrafish Mouse
sympathetic ganglion development GO:0061549 2 0.022
skeletal muscle tissue development GO:0007519 67 0.022
cellular ketone metabolic process GO:0042180 11 0.022
regulation of calcium ion transport GO:0051924 2 0.021
negative regulation of cellular component organization GO:0051129 16 0.021
regulation of cell motility GO:2000145 46 0.021
negative regulation of nervous system development GO:0051961 22 0.021
canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation GO:0060823 4 0.021
regulation of anterior head development GO:2000742 2 0.021
post anal tail morphogenesis GO:0036342 19 0.021
Zebrafish
branchiomeric skeletal muscle development GO:0014707 3 0.021
regulation of extent of cell growth GO:0061387 29 0.021
muscle system process GO:0003012 20 0.021
forebrain development GO:0030900 96 0.021
Zebrafish
ventricular cardiac muscle cell differentiation GO:0055012 6 0.021
otolith development GO:0048840 32 0.020
spinal cord anterior posterior patterning GO:0021512 1 0.020
kidney epithelium development GO:0072073 23 0.020
Zebrafish
axis elongation GO:0003401 31 0.020
Zebrafish
somite development GO:0061053 96 0.020
Zebrafish
convergent extension involved in axis elongation GO:0060028 26 0.020
Zebrafish
skin development GO:0043588 54 0.020
regulation of cell communication GO:0010646 232 0.020
Zebrafish
thymus development GO:0048538 10 0.020
positive regulation of intracellular signal transduction GO:1902533 15 0.020
protein complex subunit organization GO:0071822 46 0.020
inflammatory response GO:0006954 8 0.020
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.020
Zebrafish
cellular response to nutrient levels GO:0031669 2 0.019
female gonad development GO:0008585 4 0.019
dendrite morphogenesis GO:0048813 5 0.019
skeletal muscle organ development GO:0060538 78 0.019
post embryonic organ development GO:0048569 4 0.019
Fly
anterior posterior pattern specification GO:0009952 152 0.019
Zebrafish Fly
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.019
chemosensory behavior GO:0007635 1 0.019
Worm
organelle localization GO:0051640 49 0.019
negative regulation of epithelial cell differentiation GO:0030857 2 0.019
regulation of apoptotic process GO:0042981 98 0.019
distal tubule development GO:0072017 1 0.019
heart growth GO:0060419 7 0.019
Mouse
odontogenesis of dentin containing tooth GO:0042475 1 0.018
positive regulation of cell death GO:0010942 29 0.018
response to wounding GO:0009611 116 0.018
collagen biosynthetic process GO:0032964 2 0.018
divalent inorganic cation transport GO:0072511 21 0.018
endocardial cushion morphogenesis GO:0003203 3 0.018
Mouse
cardiac muscle cell development GO:0055013 20 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.018
cyclic purine nucleotide metabolic process GO:0052652 18 0.018
negative regulation of developmental process GO:0051093 65 0.018
Mouse
muscle organ development GO:0007517 101 0.018
Zebrafish Mouse Worm
regulation of striated muscle cell differentiation GO:0051153 6 0.018
positive regulation of bmp signaling pathway GO:0030513 10 0.018
neuron projection guidance GO:0097485 86 0.017

tbx2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
artery disease DOID:0050828 0 0.019
disease of anatomical entity DOID:7 0 0.019
vascular disease DOID:178 0 0.019
cardiovascular system disease DOID:1287 0 0.019