Danio rerio

0 known processes

terfa

telomeric repeat binding factor a

(Aliases: wu:fi22b03,zgc:111909,MGC111909,zgc:114011,MGC192548,CHUNP6903,MGC114011,wu:fi15d05)

terfa biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.717
embryo development ending in birth or egg hatching GO:0009792 271 0.268
Mouse
nucleic acid metabolic process GO:0090304 244 0.220
Mouse
organic cyclic compound metabolic process GO:1901360 301 0.211
Mouse
nucleobase containing compound metabolic process GO:0006139 274 0.205
Mouse
heterocycle metabolic process GO:0046483 290 0.182
Mouse
regulation of nitrogen compound metabolic process GO:0051171 251 0.138
Mouse
regulation of signaling GO:0023051 235 0.134
gene expression GO:0010467 252 0.134
organic cyclic compound biosynthetic process GO:1901362 223 0.131
nitrogen compound metabolic process GO:0006807 319 0.124
Mouse
meiotic cell cycle process GO:1903046 3 0.112
cellular aromatic compound metabolic process GO:0006725 295 0.111
Mouse
regulation of cell communication GO:0010646 232 0.110
single organism transport GO:0044765 206 0.104
eye development GO:0001654 277 0.104
signal transduction GO:0007165 455 0.099
ribonucleoside monophosphate catabolic process GO:0009158 4 0.093
meiotic nuclear division GO:0007126 4 0.093
regulation of meiotic cell cycle GO:0051445 1 0.092
sensory organ development GO:0007423 393 0.092
cellular nitrogen compound metabolic process GO:0034641 290 0.085
Mouse
cell surface receptor signaling pathway GO:0007166 325 0.084
nuclear transport GO:0051169 4 0.082
transcription from rna polymerase ii promoter GO:0006366 80 0.080
camera type eye development GO:0043010 222 0.078
cellular macromolecule metabolic process GO:0044260 391 0.069
Mouse
regulation of signal transduction GO:0009966 225 0.068
regulation of mrna processing GO:0050684 3 0.068
positive regulation of cell cycle GO:0045787 3 0.068
nucleocytoplasmic transport GO:0006913 4 0.065
heterocycle biosynthetic process GO:0018130 215 0.064
single fertilization GO:0007338 3 0.062
regulation of cellular metabolic process GO:0031323 320 0.061
Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.060
regulation of macromolecule metabolic process GO:0060255 317 0.059
Mouse
response to stress GO:0006950 263 0.057
Mouse
specification of symmetry GO:0009799 204 0.056
regionalization GO:0003002 274 0.055
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.055
Mouse
embryonic organ morphogenesis GO:0048562 274 0.054
sensory organ morphogenesis GO:0090596 200 0.053
embryonic organ development GO:0048568 381 0.052
regulation of biosynthetic process GO:0009889 250 0.051
generation of neurons GO:0048699 385 0.051
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.050
aromatic compound biosynthetic process GO:0019438 217 0.049
establishment of localization GO:0051234 244 0.049
cognition GO:0050890 1 0.049
regulation of rna biosynthetic process GO:2001141 213 0.049
brain morphogenesis GO:0048854 18 0.049
transcription dna templated GO:0006351 181 0.048
cellular catabolic process GO:0044248 27 0.048
regulation of gene expression GO:0010468 265 0.047
heart development GO:0007507 313 0.046
regulation of metabolic process GO:0019222 359 0.046
Mouse
negative regulation of cellular process GO:0048523 283 0.046
g1 s transition of mitotic cell cycle GO:0000082 1 0.043
retina development in camera type eye GO:0060041 146 0.043
regulation of developmental process GO:0050793 247 0.043
regulation of nucleic acid templated transcription GO:1903506 213 0.042
amine metabolic process GO:0009308 2 0.041
stem cell proliferation GO:0072089 4 0.041
regulation of rna metabolic process GO:0051252 224 0.041
morphogenesis of an epithelium GO:0002009 333 0.040
regulation of stem cell differentiation GO:2000736 4 0.039
lipid storage GO:0019915 1 0.039
nucleic acid templated transcription GO:0097659 181 0.038
mitotic cell cycle process GO:1903047 48 0.038
tube morphogenesis GO:0035239 349 0.038
telomere maintenance GO:0000723 1 0.036
Mouse
organelle localization GO:0051640 49 0.036
dorsal ventral pattern formation GO:0009953 125 0.036
single organism localization GO:1902578 225 0.036
positive regulation of cellular catabolic process GO:0031331 3 0.036
cell cycle process GO:0022402 53 0.035
eye morphogenesis GO:0048592 144 0.035
regulation of chromosome segregation GO:0051983 1 0.034
regulation of stem cell proliferation GO:0072091 2 0.034
negative regulation of synapse assembly GO:0051964 2 0.034
cellular macromolecule catabolic process GO:0044265 12 0.034
positive regulation of catabolic process GO:0009896 4 0.034
homeostatic process GO:0042592 142 0.034
Mouse
transport GO:0006810 220 0.033
cellular component biogenesis GO:0044085 178 0.033
nucleoside monophosphate catabolic process GO:0009125 4 0.033
establishment of protein localization to organelle GO:0072594 4 0.033
cell projection morphogenesis GO:0048858 244 0.032
rna biosynthetic process GO:0032774 181 0.032
regulation of protein localization to nucleus GO:1900180 2 0.032
maintenance of location GO:0051235 4 0.032
pigmentation GO:0043473 85 0.031
determination of bilateral symmetry GO:0009855 204 0.031
multicellular organism growth GO:0035264 4 0.030
sister chromatid segregation GO:0000819 6 0.030
regulation of primary metabolic process GO:0080090 311 0.030
Mouse
primary neural tube formation GO:0014020 1 0.030
regulation of binding GO:0051098 3 0.030
regulation of multicellular organismal process GO:0051239 277 0.029
immune system process GO:0002376 241 0.029
macromolecular complex subunit organization GO:0043933 74 0.029
single organism metabolic process GO:0044710 217 0.029
Mouse
organelle fission GO:0048285 23 0.029
negative regulation of biological process GO:0048519 304 0.029
single organism organelle organization GO:1902589 199 0.029
Mouse
system process GO:0003008 185 0.029
rna 3 end processing GO:0031123 2 0.028
chromosome organization involved in meiosis GO:0070192 1 0.028
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.028
lateral inhibition GO:0046331 1 0.027
positive regulation of apoptotic signaling pathway GO:2001235 1 0.026
regulation of cellular ketone metabolic process GO:0010565 7 0.026
atp catabolic process GO:0006200 4 0.026
establishment of organelle localization GO:0051656 45 0.026
multi organism process GO:0051704 134 0.026
regulation of purine nucleotide catabolic process GO:0033121 2 0.026
cellular component assembly GO:0022607 170 0.026
modification dependent macromolecule catabolic process GO:0043632 3 0.026
intracellular signal transduction GO:0035556 85 0.026
female meiotic division GO:0007143 2 0.025
organelle organization GO:0006996 227 0.025
Mouse
epithelial tube morphogenesis GO:0060562 148 0.025
heterocycle catabolic process GO:0046700 15 0.024
regulation of cellular amine metabolic process GO:0033238 0 0.024
angiogenesis GO:0001525 158 0.024
positive regulation of response to stimulus GO:0048584 80 0.024
mitotic cytokinesis GO:0000281 3 0.024
nucleobase containing compound biosynthetic process GO:0034654 205 0.023
purine nucleoside monophosphate catabolic process GO:0009128 4 0.023
epidermis development GO:0008544 48 0.023
meiosis i GO:0007127 1 0.023
rna metabolic process GO:0016070 219 0.023
guanosine containing compound catabolic process GO:1901069 2 0.023
digestive tract morphogenesis GO:0048546 231 0.023
gtp metabolic process GO:0046039 4 0.023
regulation of cellular component organization GO:0051128 86 0.023
Mouse
regulation of gene silencing GO:0060968 1 0.022
organelle assembly GO:0070925 110 0.022
cell cycle g2 m phase transition GO:0044839 4 0.022
positive regulation of signal transduction GO:0009967 56 0.022
cellular biosynthetic process GO:0044249 286 0.022
cell cycle GO:0007049 93 0.022
proteasomal protein catabolic process GO:0010498 2 0.022
aging GO:0007568 2 0.022
developmental growth GO:0048589 166 0.021
carboxylic acid metabolic process GO:0019752 22 0.021
regulation of mrna splicing via spliceosome GO:0048024 3 0.021
regulation of cell cycle process GO:0010564 20 0.021
embryonic heart tube development GO:0035050 133 0.021
protein metabolic process GO:0019538 183 0.021
cellular amide metabolic process GO:0043603 4 0.020
ubiquitin dependent protein catabolic process GO:0006511 3 0.020
cell morphogenesis GO:0000902 289 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.020
regulation of macromolecule biosynthetic process GO:0010556 225 0.020
cellular protein catabolic process GO:0044257 4 0.020
cilium organization GO:0044782 71 0.020
spindle assembly GO:0051225 2 0.020
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.020
regulation of response to stimulus GO:0048583 269 0.020
skin development GO:0043588 54 0.019
regulation of intracellular signal transduction GO:1902531 57 0.019
translational initiation GO:0006413 3 0.019
cellular response to stress GO:0033554 62 0.019
Mouse
cellular response to organic substance GO:0071310 105 0.019
regulation of biological quality GO:0065008 263 0.019
Mouse
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
negative regulation of protein kinase activity GO:0006469 4 0.018
rna localization GO:0006403 4 0.018
cellular ketone metabolic process GO:0042180 11 0.018
regulation of synaptic plasticity GO:0048167 1 0.018
positive regulation of transport GO:0051050 2 0.018
positive regulation of cellular component biogenesis GO:0044089 3 0.018
negative regulation of dna metabolic process GO:0051053 4 0.018
positive regulation of gtpase activity GO:0043547 1 0.018
locomotion GO:0040011 313 0.018
neuroblast proliferation GO:0007405 2 0.018
macromolecule biosynthetic process GO:0009059 227 0.017
meiotic chromosome segregation GO:0045132 3 0.017
mrna 3 end processing GO:0031124 2 0.017
regulation of cellular biosynthetic process GO:0031326 245 0.017
negative regulation of macromolecule metabolic process GO:0010605 76 0.017
cytoskeleton dependent cytokinesis GO:0061640 3 0.017
wnt signaling pathway GO:0016055 80 0.017
vasculature development GO:0001944 278 0.017
regulation of reproductive process GO:2000241 4 0.017
negative regulation of cellular catabolic process GO:0031330 3 0.017
regulation of cellular protein catabolic process GO:1903362 1 0.017
cell substrate adhesion GO:0031589 4 0.017
cellular macromolecule biosynthetic process GO:0034645 224 0.017
modification dependent protein catabolic process GO:0019941 3 0.017
spermatid differentiation GO:0048515 2 0.017
regulation of cytoplasmic transport GO:1903649 4 0.017
reproductive process GO:0022414 40 0.017
microtubule cytoskeleton organization GO:0000226 33 0.017
biosynthetic process GO:0009058 294 0.016
regulation of erk1 and erk2 cascade GO:0070372 4 0.016
developmental process involved in reproduction GO:0003006 27 0.016
negative regulation of protein phosphorylation GO:0001933 4 0.016
negative regulation of response to stimulus GO:0048585 104 0.016
chordate embryonic development GO:0043009 271 0.016
Mouse
body morphogenesis GO:0010171 16 0.016
protein targeting to nucleus GO:0044744 3 0.016
negative regulation of transcription dna templated GO:0045892 45 0.016
establishment or maintenance of cell polarity GO:0007163 29 0.016
cellular amine metabolic process GO:0044106 2 0.016
regulation of nucleocytoplasmic transport GO:0046822 2 0.016
specification of axis polarity GO:0065001 4 0.016
embryonic epithelial tube formation GO:0001838 17 0.016
spindle localization GO:0051653 12 0.016
gastrulation GO:0007369 208 0.016
cellular amino acid metabolic process GO:0006520 7 0.016
blood vessel development GO:0001568 246 0.015
neurological system process GO:0050877 62 0.015
macromolecule localization GO:0033036 54 0.015
g2 m transition of mitotic cell cycle GO:0000086 4 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.015
neuron development GO:0048666 262 0.015
cell part morphogenesis GO:0032990 246 0.015
regeneration GO:0031099 91 0.015
negative regulation of catabolic process GO:0009895 3 0.015
negative regulation of gene expression GO:0010629 65 0.015
cell migration GO:0016477 237 0.015
cellular localization GO:0051641 97 0.015
cell fate commitment GO:0045165 99 0.015
digestive tract development GO:0048565 265 0.015
macromolecule catabolic process GO:0009057 15 0.015
negative regulation of cellular metabolic process GO:0031324 77 0.015
regulation of intracellular protein transport GO:0033157 3 0.015
regulation of synapse organization GO:0050807 3 0.015
mitotic nuclear division GO:0007067 18 0.015
reproduction GO:0000003 40 0.015
protein import GO:0017038 3 0.015
positive regulation of ras protein signal transduction GO:0046579 1 0.014
positive regulation of nucleoside metabolic process GO:0045979 1 0.014
regulation of dna replication GO:0006275 3 0.014
small molecule metabolic process GO:0044281 77 0.014
endomembrane system organization GO:0010256 13 0.014
nuclear import GO:0051170 3 0.014
mitotic cell cycle GO:0000278 64 0.014
cell projection organization GO:0030030 284 0.014
single organism reproductive process GO:0044702 40 0.014
microtubule based process GO:0007017 60 0.014
regulation of mrna catabolic process GO:0061013 3 0.014
regulation of gene expression epigenetic GO:0040029 11 0.014
epithelial cilium movement GO:0003351 15 0.014
guanosine containing compound metabolic process GO:1901068 4 0.014
adherens junction organization GO:0034332 4 0.013
positive regulation of stress activated mapk cascade GO:0032874 3 0.013
protein k48 linked ubiquitination GO:0070936 1 0.013
cell cycle g1 s phase transition GO:0044843 1 0.013
negative regulation of chromosome organization GO:2001251 1 0.013
cilium assembly GO:0042384 58 0.013
anterior posterior pattern specification GO:0009952 152 0.013
negative regulation of metabolic process GO:0009892 86 0.013
regulation of notch signaling pathway GO:0008593 16 0.013
locomotory behavior GO:0007626 34 0.013
behavior GO:0007610 74 0.013
lateral line system development GO:0048925 76 0.013
cellular component morphogenesis GO:0032989 336 0.013
regulation of oocyte development GO:0060281 3 0.013
brain development GO:0007420 293 0.013
myeloid cell differentiation GO:0030099 86 0.013
mitotic cell cycle phase transition GO:0044772 9 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.013
spermatid development GO:0007286 2 0.013
protein localization GO:0008104 40 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.012
neuroblast differentiation GO:0014016 1 0.012
double strand break repair GO:0006302 3 0.012
camera type eye morphogenesis GO:0048593 108 0.012
organonitrogen compound metabolic process GO:1901564 74 0.012
maturation of ssu rrna GO:0030490 1 0.012
central nervous system development GO:0007417 387 0.012
cell proliferation GO:0008283 80 0.012
notch signaling pathway GO:0007219 35 0.012
chromosome segregation GO:0007059 12 0.012
response to external stimulus GO:0009605 264 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.012
positive regulation of notch signaling pathway GO:0045747 3 0.012
tube formation GO:0035148 25 0.012
regulation of transcription dna templated GO:0006355 213 0.012
positive regulation of macromolecule metabolic process GO:0010604 93 0.012
Mouse
organic cyclic compound catabolic process GO:1901361 15 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
positive regulation of dna metabolic process GO:0051054 1 0.012
Mouse
organic substance biosynthetic process GO:1901576 289 0.012
blood vessel morphogenesis GO:0048514 216 0.012
positive regulation of cellular metabolic process GO:0031325 94 0.011
Mouse
retina morphogenesis in camera type eye GO:0060042 79 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
gtp catabolic process GO:0006184 2 0.011
negative regulation of cellular biosynthetic process GO:0031327 55 0.011
regulation of metal ion transport GO:0010959 4 0.011
phagocytosis GO:0006909 3 0.011
determination of left right symmetry GO:0007368 179 0.011
regulation of establishment of protein localization GO:0070201 4 0.011
negative regulation of signal transduction GO:0009968 94 0.011
establishment of localization in cell GO:0051649 77 0.011
mrna export from nucleus GO:0006406 1 0.011
single organism biosynthetic process GO:0044711 71 0.011
axis specification GO:0009798 43 0.011
kidney development GO:0001822 92 0.011
positive regulation of gtp catabolic process GO:0033126 1 0.011
nuclear division GO:0000280 23 0.011
regulation of endothelial cell differentiation GO:0045601 3 0.011
pharyngeal muscle development GO:0043282 4 0.011
macromolecule modification GO:0043412 111 0.011
protein stabilization GO:0050821 2 0.011
cellular protein metabolic process GO:0044267 129 0.011
neuron projection development GO:0031175 180 0.011
multi organism reproductive process GO:0044703 36 0.011
cell death GO:0008219 121 0.010
neural tube formation GO:0001841 16 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.010
hemopoiesis GO:0030097 183 0.010
homeostasis of number of cells GO:0048872 62 0.010
positive regulation of nucleotide catabolic process GO:0030813 1 0.010
multicellular organismal homeostasis GO:0048871 29 0.010
adherens junction maintenance GO:0034334 2 0.010
cellular component movement GO:0006928 335 0.010

terfa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.046
immune system disease DOID:2914 0 0.023
bone marrow disease DOID:4961 0 0.023
hematopoietic system disease DOID:74 0 0.023
disease of metabolism DOID:0014667 0 0.013
muscular disease DOID:0080000 0 0.010
musculoskeletal system disease DOID:17 0 0.010
muscle tissue disease DOID:66 0 0.010