Danio rerio

34 known processes

tfr1b

transferrin receptor 1b

(Aliases: MGC123042)

tfr1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
vascular endothelial growth factor receptor signaling pathway GO:0048010 13 0.373
vasculature development GO:0001944 278 0.226
blood vessel morphogenesis GO:0048514 216 0.220
sprouting angiogenesis GO:0002040 53 0.186
generation of neurons GO:0048699 385 0.165
angiogenesis GO:0001525 158 0.159
response to nutrient GO:0007584 3 0.135
larval development GO:0002164 2 0.121
blood vessel development GO:0001568 246 0.119
response to chemical GO:0042221 320 0.113
neuron differentiation GO:0030182 353 0.109
endothelial cell fate commitment GO:0060839 3 0.104
nitrogen compound metabolic process GO:0006807 319 0.103
stem cell proliferation GO:0072089 4 0.101
fertilization GO:0009566 3 0.094
signal transduction GO:0007165 455 0.093
neuroblast proliferation GO:0007405 2 0.091
chemosensory behavior GO:0007635 1 0.087
aging GO:0007568 2 0.081
single fertilization GO:0007338 3 0.080
cell surface receptor signaling pathway GO:0007166 325 0.079
aromatic compound biosynthetic process GO:0019438 217 0.078
gene expression GO:0010467 252 0.073
nucleobase containing compound metabolic process GO:0006139 274 0.072
regulation of developmental process GO:0050793 247 0.071
embryonic organ development GO:0048568 381 0.066
Zebrafish
regulation of macromolecule metabolic process GO:0060255 317 0.062
negative regulation of biological process GO:0048519 304 0.061
regulation of cellular ketone metabolic process GO:0010565 7 0.060
regulation of primary metabolic process GO:0080090 311 0.060
lipid storage GO:0019915 1 0.059
regulation of cellular metabolic process GO:0031323 320 0.058
enzyme linked receptor protein signaling pathway GO:0007167 106 0.056
cellular macromolecule biosynthetic process GO:0034645 224 0.056
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.056
regulation of multicellular organismal process GO:0051239 277 0.055
Mouse
nucleic acid metabolic process GO:0090304 244 0.053
sensory perception of chemical stimulus GO:0007606 3 0.052
regulation of gene expression GO:0010468 265 0.052
response to external stimulus GO:0009605 264 0.051
maintenance of location GO:0051235 4 0.051
regulation of macromolecule biosynthetic process GO:0010556 225 0.050
tissue remodeling GO:0048771 4 0.050
Mouse
transcription from rna polymerase iii promoter GO:0006383 1 0.049
regulation of cellular biosynthetic process GO:0031326 245 0.049
cellular macromolecule metabolic process GO:0044260 391 0.048
nucleobase containing compound biosynthetic process GO:0034654 205 0.048
heart development GO:0007507 313 0.047
cellular ketone metabolic process GO:0042180 11 0.047
neuron development GO:0048666 262 0.047
cell fate commitment GO:0045165 99 0.046
macromolecule biosynthetic process GO:0009059 227 0.046
cellular aromatic compound metabolic process GO:0006725 295 0.045
regulation of metabolic process GO:0019222 359 0.045
nuclear migration GO:0007097 3 0.045
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.044
retinoic acid receptor signaling pathway GO:0048384 16 0.044
outflow tract morphogenesis GO:0003151 1 0.043
chordate embryonic development GO:0043009 271 0.043
rna biosynthetic process GO:0032774 181 0.042
response to organic substance GO:0010033 153 0.041
morphogenesis of an epithelium GO:0002009 333 0.041
neurological system process GO:0050877 62 0.041
negative regulation of cellular process GO:0048523 283 0.040
embryo development ending in birth or egg hatching GO:0009792 271 0.039
organic cyclic compound metabolic process GO:1901360 301 0.039
neural precursor cell proliferation GO:0061351 20 0.039
hormone transport GO:0009914 2 0.038
stem cell division GO:0017145 1 0.038
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.038
growth GO:0040007 174 0.037
negative regulation of macromolecule metabolic process GO:0010605 76 0.036
carboxylic acid metabolic process GO:0019752 22 0.036
cellular response to lipopolysaccharide GO:0071222 3 0.036
negative regulation of synapse assembly GO:0051964 2 0.036
regulation of transcription dna templated GO:0006355 213 0.035
rna metabolic process GO:0016070 219 0.035
regulation of nitrogen compound metabolic process GO:0051171 251 0.034
regulation of biological quality GO:0065008 263 0.034
reflex GO:0060004 2 0.034
cellular biosynthetic process GO:0044249 286 0.033
developmental growth involved in morphogenesis GO:0060560 86 0.033
cell matrix adhesion GO:0007160 4 0.033
sensory organ development GO:0007423 393 0.033
cellular component morphogenesis GO:0032989 336 0.032
gland development GO:0048732 143 0.032
positive regulation of cell cycle GO:0045787 3 0.032
negative regulation of chemotaxis GO:0050922 4 0.032
cell morphogenesis GO:0000902 289 0.031
organic acid metabolic process GO:0006082 31 0.031
axonogenesis GO:0007409 152 0.031
cell substrate adhesion GO:0031589 4 0.031
cellular nitrogen compound biosynthetic process GO:0044271 218 0.030
biosynthetic process GO:0009058 294 0.030
cellular component movement GO:0006928 335 0.029
homeostatic process GO:0042592 142 0.029
cellular response to chemical stimulus GO:0070887 157 0.029
multicellular organism growth GO:0035264 4 0.029
transport GO:0006810 220 0.028
regulation of biosynthetic process GO:0009889 250 0.028
system process GO:0003008 185 0.028
hepaticobiliary system development GO:0061008 98 0.028
regulation of cell shape GO:0008360 1 0.028
regulation of synapse organization GO:0050807 3 0.028
regulation of fatty acid metabolic process GO:0019217 1 0.027
regulation of rna metabolic process GO:0051252 224 0.027
translational initiation GO:0006413 3 0.027
response to oxygen containing compound GO:1901700 55 0.027
protein homooligomerization GO:0051260 3 0.027
regulation of synapse assembly GO:0051963 3 0.027
regulation of rna biosynthetic process GO:2001141 213 0.026
regulation of myelination GO:0031641 1 0.026
negative regulation of gene expression GO:0010629 65 0.026
establishment of localization GO:0051234 244 0.026
lymphangiogenesis GO:0001946 25 0.026
oxoacid metabolic process GO:0043436 31 0.026
eye morphogenesis GO:0048592 144 0.025
cellular nitrogen compound metabolic process GO:0034641 290 0.025
response to lipid GO:0033993 60 0.025
cellular response to biotic stimulus GO:0071216 3 0.025
muscle structure development GO:0061061 196 0.025
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.025
lymph vessel morphogenesis GO:0036303 25 0.025
central nervous system development GO:0007417 387 0.024
epithelial cell differentiation GO:0030855 116 0.024
nucleic acid templated transcription GO:0097659 181 0.024
organic cyclic compound biosynthetic process GO:1901362 223 0.024
single organism metabolic process GO:0044710 217 0.024
phagocytosis GO:0006909 3 0.024
establishment of protein localization to organelle GO:0072594 4 0.024
organelle organization GO:0006996 227 0.024
regulation of dendrite development GO:0050773 3 0.024
negative regulation of cellular biosynthetic process GO:0031327 55 0.024
multicellular organismal signaling GO:0035637 22 0.024
neuron projection development GO:0031175 180 0.024
regulation of circadian rhythm GO:0042752 4 0.023
small molecule metabolic process GO:0044281 77 0.023
heterocycle metabolic process GO:0046483 290 0.023
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.023
lymphatic endothelial cell differentiation GO:0060836 1 0.023
embryonic heart tube development GO:0035050 133 0.023
heterocycle biosynthetic process GO:0018130 215 0.023
regulation of signaling GO:0023051 235 0.022
pronuclear migration GO:0035046 1 0.022
regulation of nucleic acid templated transcription GO:1903506 213 0.022
single organism organelle organization GO:1902589 199 0.022
positive regulation of transport GO:0051050 2 0.022
transcription dna templated GO:0006351 181 0.022
positive regulation of cell adhesion GO:0045785 1 0.022
transcription from rna polymerase ii promoter GO:0006366 80 0.022
axon development GO:0061564 166 0.022
neuronal action potential GO:0019228 18 0.021
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.021
toll like receptor signaling pathway GO:0002224 4 0.021
negative regulation of cellular metabolic process GO:0031324 77 0.021
eye development GO:0001654 277 0.021
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.021
positive regulation of translation GO:0045727 1 0.021
response to organic cyclic compound GO:0014070 51 0.021
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.021
cellular lipid catabolic process GO:0044242 3 0.020
retina development in camera type eye GO:0060041 146 0.020
negative regulation of rna metabolic process GO:0051253 48 0.020
immune system development GO:0002520 191 0.020
Zebrafish Mouse
hormone secretion GO:0046879 2 0.020
cellular lipid metabolic process GO:0044255 36 0.020
digestive system development GO:0055123 289 0.020
convergent extension GO:0060026 118 0.020
cellular component biogenesis GO:0044085 178 0.019
lymph vessel development GO:0001945 27 0.019
primary neural tube formation GO:0014020 1 0.019
skeletal muscle tissue development GO:0007519 67 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.019
organelle localization GO:0051640 49 0.019
female sex differentiation GO:0046660 4 0.019
interspecies interaction between organisms GO:0044419 4 0.019
negative regulation of metabolic process GO:0009892 86 0.019
regulation of cellular component organization GO:0051128 86 0.019
myelination GO:0042552 18 0.019
muscle organ development GO:0007517 101 0.019
cell projection organization GO:0030030 284 0.019
multi organism cellular process GO:0044764 2 0.019
homeostasis of number of cells GO:0048872 62 0.019
Zebrafish
lymphatic endothelial cell fate commitment GO:0060838 1 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.019
regulation of cell substrate adhesion GO:0010810 1 0.018
action potential GO:0001508 19 0.018
specification of symmetry GO:0009799 204 0.018
developmental growth GO:0048589 166 0.018
positive regulation of cellular process GO:0048522 201 0.018
protein targeting to nucleus GO:0044744 3 0.018
tube closure GO:0060606 1 0.018
multi organism process GO:0051704 134 0.018
axon extension GO:0048675 45 0.018
single organism membrane fusion GO:0044801 2 0.018
negative regulation of rna biosynthetic process GO:1902679 45 0.018
nucleocytoplasmic transport GO:0006913 4 0.018
nuclear transport GO:0051169 4 0.018
liver development GO:0001889 96 0.018
protein import GO:0017038 3 0.018
regulation of nervous system development GO:0051960 90 0.018
axon midline choice point recognition GO:0016199 4 0.018
regulation of multicellular organismal development GO:2000026 223 0.017
developmental cell growth GO:0048588 52 0.017
regulation of multicellular organism growth GO:0040014 4 0.017
alcohol biosynthetic process GO:0046165 2 0.017
regulation of cytokine production GO:0001817 3 0.017
guanosine containing compound catabolic process GO:1901069 2 0.017
regulation of anatomical structure morphogenesis GO:0022603 130 0.017
regulation of cell activation GO:0050865 1 0.017
protein import into nucleus GO:0006606 3 0.017
response to stress GO:0006950 263 0.017
positive regulation of cellular component biogenesis GO:0044089 3 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.017
cell part morphogenesis GO:0032990 246 0.017
positive regulation of biological process GO:0048518 253 0.017
Mouse
brain development GO:0007420 293 0.017
response to carbohydrate GO:0009743 3 0.016
mitochondrion organization GO:0007005 4 0.016
camera type eye development GO:0043010 222 0.016
response to acid chemical GO:0001101 17 0.016
circulatory system process GO:0003013 87 0.016
stem cell maintenance GO:0019827 4 0.016
regulation of reproductive process GO:2000241 4 0.016
locomotion GO:0040011 313 0.016
organic substance biosynthetic process GO:1901576 289 0.016
embryonic hemopoiesis GO:0035162 53 0.016
Zebrafish
intracellular receptor signaling pathway GO:0030522 30 0.016
regulation of establishment of protein localization GO:0070201 4 0.016
myeloid cell homeostasis GO:0002262 56 0.016
Zebrafish
endothelial cell differentiation GO:0045446 20 0.016
regulation of epithelial cell proliferation GO:0050678 3 0.016
negative regulation of biosynthetic process GO:0009890 55 0.016
cellular response to hormone stimulus GO:0032870 39 0.016
regulation of protein targeting GO:1903533 2 0.016
cell projection morphogenesis GO:0048858 244 0.015
regulation of protein transport GO:0051223 3 0.015
determination of dorsal ventral asymmetry GO:0048262 34 0.015
response to abiotic stimulus GO:0009628 122 0.015
regulation of cell communication GO:0010646 232 0.015
response to corticosteroid GO:0031960 1 0.015
heart process GO:0003015 71 0.015
membrane fusion GO:0061025 2 0.015
cellular transition metal ion homeostasis GO:0046916 3 0.015
regulation of cell matrix adhesion GO:0001952 1 0.015
somatic muscle development GO:0007525 4 0.015
lipid metabolic process GO:0006629 52 0.015
mitochondrial transport GO:0006839 2 0.015
erythrocyte homeostasis GO:0034101 55 0.015
Zebrafish
endothelium development GO:0003158 25 0.015
dorsal ventral pattern formation GO:0009953 125 0.015
monocarboxylic acid catabolic process GO:0072329 3 0.015
organic acid catabolic process GO:0016054 3 0.015
response to endogenous stimulus GO:0009719 83 0.015
cell proliferation GO:0008283 80 0.015
response to glucocorticoid GO:0051384 1 0.015
determination of left right symmetry GO:0007368 179 0.015
cellular component assembly GO:0022607 170 0.015
nuclear import GO:0051170 3 0.015
positive regulation of catabolic process GO:0009896 4 0.014
regulation of stem cell proliferation GO:0072091 2 0.014
amine metabolic process GO:0009308 2 0.014
nucleus localization GO:0051647 8 0.014
regulation of membrane potential GO:0042391 23 0.014
cellular localization GO:0051641 97 0.014
single organism nuclear import GO:1902593 3 0.014
negative regulation of cell differentiation GO:0045596 46 0.014
regulation of cytoplasmic transport GO:1903649 4 0.014
cellular response to extracellular stimulus GO:0031668 2 0.014
leukocyte proliferation GO:0070661 1 0.014
macromolecular complex assembly GO:0065003 35 0.014
heart morphogenesis GO:0003007 156 0.014
regulation of intracellular protein transport GO:0033157 3 0.014
death GO:0016265 121 0.014
regulation of programmed cell death GO:0043067 101 0.014
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.014
positive regulation of secretion by cell GO:1903532 1 0.014
sensory organ morphogenesis GO:0090596 200 0.014
striated muscle tissue development GO:0014706 110 0.014
positive regulation of rna biosynthetic process GO:1902680 57 0.013
ameboidal type cell migration GO:0001667 143 0.013
endocrine process GO:0050886 2 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
peptide transport GO:0015833 1 0.013
lipid catabolic process GO:0016042 4 0.013
eye photoreceptor cell development GO:0042462 30 0.013
positive regulation of cytokine production GO:0001819 2 0.013
positive regulation of cellular catabolic process GO:0031331 3 0.013
positive regulation of cell activation GO:0050867 1 0.013
pericardium morphogenesis GO:0003344 1 0.013
extrinsic apoptotic signaling pathway GO:0097191 3 0.013
regulation of cyclase activity GO:0031279 12 0.013
behavior GO:0007610 74 0.013
cellular response to external stimulus GO:0071496 2 0.013
regionalization GO:0003002 274 0.013
muscle tissue development GO:0060537 110 0.013
retina morphogenesis in camera type eye GO:0060042 79 0.013
protein localization to nucleus GO:0034504 3 0.013
positive regulation of secretion GO:0051047 1 0.013
regulation of protein catabolic process GO:0042176 1 0.013
proteasomal protein catabolic process GO:0010498 2 0.013
cellular response to molecule of bacterial origin GO:0071219 3 0.013
regulation of translational initiation GO:0006446 1 0.012
photoreceptor cell development GO:0042461 40 0.012
spermatid differentiation GO:0048515 2 0.012
regulation of neuron projection development GO:0010975 40 0.012
cell aging GO:0007569 2 0.012
cytoskeleton organization GO:0007010 96 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
establishment of organelle localization GO:0051656 45 0.012
positive regulation of immune effector process GO:0002699 3 0.012
organelle fusion GO:0048284 3 0.012
aorta development GO:0035904 4 0.012
lateral mesoderm development GO:0048368 23 0.012
regulation of signal transduction GO:0009966 225 0.012
multicellular organismal response to stress GO:0033555 2 0.012
central nervous system neuron axonogenesis GO:0021955 18 0.012
pronephros development GO:0048793 69 0.012
regulation of cell development GO:0060284 100 0.012
regulation of inflammatory response GO:0050727 2 0.012
cellular amine metabolic process GO:0044106 2 0.012
response to drug GO:0042493 3 0.012
transmission of nerve impulse GO:0019226 19 0.012
somite development GO:0061053 96 0.012
response to monosaccharide GO:0034284 3 0.012
programmed cell death GO:0012501 119 0.012
apoptotic process GO:0006915 116 0.012
erythrocyte differentiation GO:0030218 54 0.012
Zebrafish
cell growth GO:0016049 57 0.012
cytokinesis GO:0000910 3 0.012
guanosine containing compound metabolic process GO:1901068 4 0.012
growth plate cartilage development GO:0003417 2 0.012
regulation of protein complex assembly GO:0043254 3 0.012
positive regulation of cellular metabolic process GO:0031325 94 0.012
phototransduction GO:0007602 2 0.012
response to glucose GO:0009749 3 0.012
regulation of extent of cell growth GO:0061387 29 0.012
cell death GO:0008219 121 0.012
lamellipodium assembly GO:0030032 1 0.012
pharyngeal muscle development GO:0043282 4 0.011
central nervous system neuron differentiation GO:0021953 74 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.011
sequestering of metal ion GO:0051238 3 0.011
endocrine hormone secretion GO:0060986 2 0.011
cellular protein catabolic process GO:0044257 4 0.011
determination of bilateral symmetry GO:0009855 204 0.011
pericardium development GO:0060039 1 0.011
spermatid development GO:0007286 2 0.011
actin cytoskeleton organization GO:0030036 63 0.011
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.011
muscle cell differentiation GO:0042692 139 0.011
regulation of axon extension GO:0030516 24 0.011
regulation of organ growth GO:0046620 3 0.011
regulation of cell death GO:0010941 103 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
negative regulation of nucleic acid templated transcription GO:1903507 45 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
positive regulation of transcription dna templated GO:0045893 57 0.011
adult behavior GO:0030534 2 0.011
sensory perception GO:0007600 39 0.011
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.011
epithelial cell migration GO:0010631 25 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.011
cellular response to organic substance GO:0071310 105 0.011
immune system process GO:0002376 241 0.011
Zebrafish Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
regulation of response to stimulus GO:0048583 269 0.011
embryonic limb morphogenesis GO:0030326 2 0.011
cellular response to endogenous stimulus GO:0071495 68 0.010
cell proliferation involved in heart morphogenesis GO:0061323 2 0.010
chemotaxis GO:0006935 104 0.010
digestive tract development GO:0048565 265 0.010
signal transduction in absence of ligand GO:0038034 1 0.010
cell morphogenesis involved in differentiation GO:0000904 195 0.010
membrane invagination GO:0010324 1 0.010
segmentation GO:0035282 97 0.010
positive regulation of cellular biosynthetic process GO:0031328 68 0.010
i kappab kinase nf kappab signaling GO:0007249 4 0.010
neuron projection extension GO:1990138 45 0.010
positive regulation of ras protein signal transduction GO:0046579 1 0.010
modification dependent macromolecule catabolic process GO:0043632 3 0.010
negative regulation of developmental process GO:0051093 65 0.010
ubiquitin dependent protein catabolic process GO:0006511 3 0.010
negative regulation of multicellular organismal process GO:0051241 69 0.010
positive regulation of stem cell proliferation GO:2000648 1 0.010
rna localization GO:0006403 4 0.010
cellular amino acid metabolic process GO:0006520 7 0.010

tfr1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.061
disease of metabolism DOID:0014667 0 0.016
inherited metabolic disorder DOID:655 0 0.016
immune system disease DOID:2914 0 0.014
nervous system disease DOID:863 0 0.014
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013