Danio rerio

0 known processes

thbs1

thrombospondin 1

(Aliases: Tsp-1,si:dkey-11e23.1,wu:fc48c03)

thbs1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory organ development GO:0007423 393 0.707
heart morphogenesis GO:0003007 156 0.575
Mouse
embryonic organ development GO:0048568 381 0.525
cartilage development GO:0051216 96 0.522
Mouse
heart development GO:0007507 313 0.443
Mouse
vasculature development GO:0001944 278 0.437
Human Mouse
sensory organ morphogenesis GO:0090596 200 0.401
negative regulation of biological process GO:0048519 304 0.361
Human Mouse
heterocycle biosynthetic process GO:0018130 215 0.327
biosynthetic process GO:0009058 294 0.320
Human
organic substance biosynthetic process GO:1901576 289 0.302
Human
nitrogen compound metabolic process GO:0006807 319 0.263
Human
regulation of signal transduction GO:0009966 225 0.252
Human Mouse
heterocycle metabolic process GO:0046483 290 0.238
Human
regulation of response to stimulus GO:0048583 269 0.234
Human Mouse
response to external stimulus GO:0009605 264 0.219
Human Mouse
blood vessel development GO:0001568 246 0.209
Human Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.203
Human
generation of neurons GO:0048699 385 0.202
cell surface receptor signaling pathway GO:0007166 325 0.197
Human Mouse
regulation of metabolic process GO:0019222 359 0.180
Human
regulation of epithelial cell proliferation GO:0050678 3 0.178
Human Mouse
embryonic organ morphogenesis GO:0048562 274 0.172
cellular nitrogen compound metabolic process GO:0034641 290 0.165
Human
chordate embryonic development GO:0043009 271 0.161
morphogenesis of an epithelium GO:0002009 333 0.157
regulation of nucleic acid templated transcription GO:1903506 213 0.156
aromatic compound biosynthetic process GO:0019438 217 0.155
growth GO:0040007 174 0.153
Mouse
eye morphogenesis GO:0048592 144 0.153
cell motility GO:0048870 244 0.143
Human Mouse
rna metabolic process GO:0016070 219 0.136
regulation of cellular metabolic process GO:0031323 320 0.131
Human
cellular biosynthetic process GO:0044249 286 0.131
Human
transcription dna templated GO:0006351 181 0.128
regulation of protein localization to nucleus GO:1900180 2 0.128
organic cyclic compound metabolic process GO:1901360 301 0.127
Human
signal transduction GO:0007165 455 0.125
Human Mouse
nuclear transport GO:0051169 4 0.124
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.123
Human
blood vessel morphogenesis GO:0048514 216 0.122
Human Mouse
regulation of vasculature development GO:1901342 33 0.121
Human Mouse
nucleobase containing compound biosynthetic process GO:0034654 205 0.120
regionalization GO:0003002 274 0.118
embryo development ending in birth or egg hatching GO:0009792 271 0.118
regulation of macromolecule metabolic process GO:0060255 317 0.116
Human
skeletal system development GO:0001501 181 0.113
Mouse
cell migration GO:0016477 237 0.112
Human Mouse
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.109
Human
tube morphogenesis GO:0035239 349 0.108
multicellular organism growth GO:0035264 4 0.106
eye development GO:0001654 277 0.104
cell death GO:0008219 121 0.104
Human
negative regulation of cellular process GO:0048523 283 0.103
Human Mouse
regulation of multicellular organismal development GO:2000026 223 0.102
Human Mouse
collagen fibril organization GO:0030199 1 0.097
regulation of multicellular organismal process GO:0051239 277 0.097
Human Mouse
extracellular structure organization GO:0043062 27 0.096
cell projection organization GO:0030030 284 0.094
skeletal system morphogenesis GO:0048705 102 0.093
Mouse
cell morphogenesis involved in differentiation GO:0000904 195 0.092
response to amino acid GO:0043200 2 0.090
aging GO:0007568 2 0.087
appendage development GO:0048736 80 0.087
cellular macromolecule metabolic process GO:0044260 391 0.084
Human
apoptotic process GO:0006915 116 0.083
Human
cellular response to extracellular stimulus GO:0031668 2 0.081
regulation of biosynthetic process GO:0009889 250 0.081
Human
regulation of endothelial cell proliferation GO:0001936 1 0.080
Human Mouse
response to chemical GO:0042221 320 0.079
Human Mouse
notochord development GO:0030903 54 0.078
tissue remodeling GO:0048771 4 0.078
regulation of primary metabolic process GO:0080090 311 0.077
Human
cellular response to external stimulus GO:0071496 2 0.077
nucleobase containing compound metabolic process GO:0006139 274 0.077
Human
negative regulation of multicellular organismal process GO:0051241 69 0.076
Human Mouse
negative regulation of protein phosphorylation GO:0001933 4 0.076
larval development GO:0002164 2 0.076
localization of cell GO:0051674 244 0.075
Human Mouse
peptidyl serine modification GO:0018209 2 0.074
rna biosynthetic process GO:0032774 181 0.073
regulation of blood pressure GO:0008217 1 0.072
regulation of rna metabolic process GO:0051252 224 0.072
nucleic acid templated transcription GO:0097659 181 0.070
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.070
negative regulation of cell communication GO:0010648 96 0.070
Human
cellular aromatic compound metabolic process GO:0006725 295 0.070
Human
regulation of cellular ketone metabolic process GO:0010565 7 0.068
immune system process GO:0002376 241 0.068
Human Mouse
transcription from rna polymerase ii promoter GO:0006366 80 0.068
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.067
cellular ketone metabolic process GO:0042180 11 0.065
organonitrogen compound metabolic process GO:1901564 74 0.065
Human
protein localization to nucleus GO:0034504 3 0.065
cellular nitrogen compound biosynthetic process GO:0044271 218 0.064
amine metabolic process GO:0009308 2 0.064
regulation of erk1 and erk2 cascade GO:0070372 4 0.063
establishment of protein localization to organelle GO:0072594 4 0.063
nucleocytoplasmic transport GO:0006913 4 0.063
camera type eye morphogenesis GO:0048593 108 0.063
gene expression GO:0010467 252 0.061
Human
camera type eye development GO:0043010 222 0.059
muscle organ development GO:0007517 101 0.059
Fly
meiotic nuclear division GO:0007126 4 0.059
gland development GO:0048732 143 0.058
protein import into nucleus GO:0006606 3 0.058
regulation of rna biosynthetic process GO:2001141 213 0.058
negative regulation of developmental process GO:0051093 65 0.058
Human Mouse
positive regulation of cell cycle GO:0045787 3 0.057
response to stress GO:0006950 263 0.056
Human Mouse
regulation of nitrogen compound metabolic process GO:0051171 251 0.056
Human
single organism nuclear import GO:1902593 3 0.056
regulation of gene expression GO:0010468 265 0.056
Human
developmental growth GO:0048589 166 0.056
Mouse
cellular amine metabolic process GO:0044106 2 0.055
regulation of binding GO:0051098 3 0.055
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.054
Human Mouse
chondrocyte development GO:0002063 4 0.054
macromolecule biosynthetic process GO:0009059 227 0.054
Human
regulation of cellular amine metabolic process GO:0033238 0 0.054
negative regulation of signal transduction GO:0009968 94 0.053
Human
response to drug GO:0042493 3 0.053
Human
erk1 and erk2 cascade GO:0070371 4 0.053
nucleic acid metabolic process GO:0090304 244 0.052
protein targeting to nucleus GO:0044744 3 0.052
small molecule metabolic process GO:0044281 77 0.052
Human
primary neural tube formation GO:0014020 1 0.052
cellular protein metabolic process GO:0044267 129 0.051
Human
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.049
cellular macromolecule biosynthetic process GO:0034645 224 0.049
Human
extracellular matrix organization GO:0030198 27 0.049
positive regulation of cellular amine metabolic process GO:0033240 0 0.049
cell morphogenesis GO:0000902 289 0.048
regulation of cytoplasmic transport GO:1903649 4 0.048
response to corticosteroid GO:0031960 1 0.047
outflow tract morphogenesis GO:0003151 1 0.047
Mouse
neuron differentiation GO:0030182 353 0.047
positive regulation of response to stimulus GO:0048584 80 0.046
Human Mouse
angiogenesis GO:0001525 158 0.046
Human Mouse
cellular response to chemical stimulus GO:0070887 157 0.045
Human Mouse
positive regulation of biological process GO:0048518 253 0.045
Human Mouse
positive regulation of cellular metabolic process GO:0031325 94 0.045
Human
embryonic cranial skeleton morphogenesis GO:0048701 90 0.044
digestive tract morphogenesis GO:0048546 231 0.044
hemopoiesis GO:0030097 183 0.043
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.043
embryonic skeletal system development GO:0048706 97 0.042
positive regulation of cellular process GO:0048522 201 0.042
Human Mouse
cellular response to organic substance GO:0071310 105 0.042
Human Mouse
regulation of protein targeting GO:1903533 2 0.042
cognition GO:0050890 1 0.041
nuclear import GO:0051170 3 0.041
determination of left right symmetry GO:0007368 179 0.041
regulation of multicellular organism growth GO:0040014 4 0.041
response to abiotic stimulus GO:0009628 122 0.040
negative regulation of signaling GO:0023057 96 0.040
Human
cellular component morphogenesis GO:0032989 336 0.040
hematopoietic or lymphoid organ development GO:0048534 191 0.040
wnt signaling pathway GO:0016055 80 0.040
connective tissue development GO:0061448 99 0.039
Zebrafish Mouse
cardiac muscle tissue development GO:0048738 48 0.039
enzyme linked receptor protein signaling pathway GO:0007167 106 0.039
Human Mouse
organic cyclic compound biosynthetic process GO:1901362 223 0.039
bmp signaling pathway GO:0030509 52 0.038
convergent extension GO:0060026 118 0.038
death GO:0016265 121 0.038
Human
homeostatic process GO:0042592 142 0.038
negative regulation of macromolecule metabolic process GO:0010605 76 0.038
Human
oxoacid metabolic process GO:0043436 31 0.037
neurological system process GO:0050877 62 0.037
cellular response to stress GO:0033554 62 0.036
Mouse
phagocytosis GO:0006909 3 0.036
Human
protein stabilization GO:0050821 2 0.036
programmed cell death GO:0012501 119 0.036
Human
organic acid metabolic process GO:0006082 31 0.035
response to organic substance GO:0010033 153 0.035
Human Mouse
macromolecule modification GO:0043412 111 0.035
Human
positive regulation of cellular catabolic process GO:0031331 3 0.034
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.034
single organism biosynthetic process GO:0044711 71 0.034
regulation of nucleocytoplasmic transport GO:0046822 2 0.034
regulation of angiogenesis GO:0045765 26 0.034
Human Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.033
cellular protein modification process GO:0006464 100 0.033
Human
positive regulation of apoptotic process GO:0043065 29 0.032
Human
immune system development GO:0002520 191 0.032
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.032
Human Mouse
regulation of intracellular signal transduction GO:1902531 57 0.031
Human
liver development GO:0001889 96 0.031
proteoglycan metabolic process GO:0006029 14 0.031
response to nutrient GO:0007584 3 0.031
regulation of anatomical structure morphogenesis GO:0022603 130 0.031
Human Mouse
negative regulation of gene expression GO:0010629 65 0.031
Human
cellular response to nutrient levels GO:0031669 2 0.031
neuron projection morphogenesis GO:0048812 161 0.031
regulation of cell communication GO:0010646 232 0.031
Human Mouse
regulation of cysteine type endopeptidase activity GO:2000116 21 0.031
Human
protein metabolic process GO:0019538 183 0.031
Human
positive regulation of signaling GO:0023056 56 0.030
Human Mouse
inner ear morphogenesis GO:0042472 63 0.030
gastrulation GO:0007369 208 0.030
endothelial cell proliferation GO:0001935 11 0.030
Human Mouse
cell part morphogenesis GO:0032990 246 0.030
cellular carbohydrate metabolic process GO:0044262 4 0.030
smoothened signaling pathway GO:0007224 30 0.029
regulation of meiotic cell cycle GO:0051445 1 0.029
regulation of protein import into nucleus GO:0042306 2 0.029
cellular response to xenobiotic stimulus GO:0071466 35 0.029
positive regulation of translation GO:0045727 1 0.029
Human
blood circulation GO:0008015 87 0.029
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.029
Human
protein import GO:0017038 3 0.029
regulation of signaling GO:0023051 235 0.029
Human Mouse
response to hydrogen peroxide GO:0042542 3 0.028
response to inorganic substance GO:0010035 38 0.028
Human Mouse
anatomical structure homeostasis GO:0060249 36 0.028
embryonic skeletal system morphogenesis GO:0048704 93 0.028
morphogenesis of an epithelial sheet GO:0002011 49 0.028
response to wounding GO:0009611 116 0.028
Human
convergent extension involved in axis elongation GO:0060028 26 0.028
positive regulation of biosynthetic process GO:0009891 68 0.028
Human
neuroblast differentiation GO:0014016 1 0.028
regulation of embryonic development GO:0045995 47 0.028
inner ear development GO:0048839 126 0.027
response to nutrient levels GO:0031667 10 0.027
energy reserve metabolic process GO:0006112 2 0.027
regulation of cellular amino acid metabolic process GO:0006521 0 0.027
regulation of establishment of protein localization GO:0070201 4 0.027
chemotaxis GO:0006935 104 0.027
Human Mouse
neuron projection development GO:0031175 180 0.027
negative regulation of metabolic process GO:0009892 86 0.027
Human
epithelial tube morphogenesis GO:0060562 148 0.027
single organism localization GO:1902578 225 0.027
Human
regulation of intracellular protein transport GO:0033157 3 0.027
collagen metabolic process GO:0032963 2 0.026
regulation of establishment of planar polarity GO:0090175 4 0.026
positive regulation of cytoskeleton organization GO:0051495 3 0.026
head development GO:0060322 303 0.025
lipid storage GO:0019915 1 0.025
circulatory system process GO:0003013 87 0.025
glycoprotein metabolic process GO:0009100 23 0.025
negative regulation of cellular metabolic process GO:0031324 77 0.025
Human
positive regulation of nucleic acid templated transcription GO:1903508 57 0.025
determination of bilateral symmetry GO:0009855 204 0.025
ventricular cardiac muscle tissue development GO:0003229 3 0.025
cellular response to endogenous stimulus GO:0071495 68 0.025
Human Mouse
olfactory lobe development GO:0021988 4 0.025
carbohydrate homeostasis GO:0033500 1 0.025
neural tube development GO:0021915 62 0.025
skeletal muscle organ development GO:0060538 78 0.025
Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.024
regulation of wnt signaling pathway GO:0030111 53 0.024
positive regulation of transport GO:0051050 2 0.024
regulation of protein transport GO:0051223 3 0.024
somitogenesis GO:0001756 87 0.024
determination of heart left right asymmetry GO:0061371 117 0.024
positive regulation of myeloid cell differentiation GO:0045639 2 0.024
embryonic limb morphogenesis GO:0030326 2 0.024
regulation of transcription dna templated GO:0006355 213 0.024
ameboidal type cell migration GO:0001667 143 0.024
Human
cell substrate junction assembly GO:0007044 2 0.024
regulation of cellular protein metabolic process GO:0032268 52 0.024
Human
embryonic heart tube morphogenesis GO:0003143 108 0.024
regulation of reproductive process GO:2000241 4 0.024
intracellular receptor signaling pathway GO:0030522 30 0.024
specification of symmetry GO:0009799 204 0.024
lymphatic endothelial cell fate commitment GO:0060838 1 0.023
regulation of cytokine production GO:0001817 3 0.023
Human
hindbrain development GO:0030902 91 0.023
cell substrate adhesion GO:0031589 4 0.023
Human Mouse
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.023
appendage morphogenesis GO:0035107 56 0.023
phosphorus metabolic process GO:0006793 109 0.023
Human
cellular component movement GO:0006928 335 0.023
Human Mouse
single organism transport GO:0044765 206 0.023
Human
cell projection morphogenesis GO:0048858 244 0.022
digestive system development GO:0055123 289 0.022
macromolecular complex subunit organization GO:0043933 74 0.022
positive regulation of macromolecule metabolic process GO:0010604 93 0.022
Human
regulation of response to external stimulus GO:0032101 31 0.022
Human Mouse
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.022
Human
sexual reproduction GO:0019953 36 0.022
response to carbohydrate GO:0009743 3 0.022
Human
regulation of protein binding GO:0043393 3 0.021
canonical wnt signaling pathway GO:0060070 48 0.021
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.021
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.021
positive regulation of metabolic process GO:0009893 108 0.021
Human
regulation of macromolecule biosynthetic process GO:0010556 225 0.021
Human
brain development GO:0007420 293 0.021
establishment of localization GO:0051234 244 0.021
Human
regeneration GO:0031099 91 0.021
cellular localization GO:0051641 97 0.021
g1 s transition of mitotic cell cycle GO:0000082 1 0.021
negative regulation of gastrulation GO:2000542 11 0.021
meiotic chromosome segregation GO:0045132 3 0.020
positive regulation of epithelial cell proliferation GO:0050679 1 0.020
maintenance of location GO:0051235 4 0.020
regulation of receptor activity GO:0010469 2 0.020
cellular component biogenesis GO:0044085 178 0.020
multi organism process GO:0051704 134 0.020
carboxylic acid metabolic process GO:0019752 22 0.020
cardiac chamber morphogenesis GO:0003206 12 0.020
regulation of cell division GO:0051302 12 0.020
retina morphogenesis in camera type eye GO:0060042 79 0.020
transport GO:0006810 220 0.020
Human
regulation of endopeptidase activity GO:0052548 23 0.020
Human
cellular amino acid metabolic process GO:0006520 7 0.020
notch signaling pathway GO:0007219 35 0.020
regulation of purine nucleotide catabolic process GO:0033121 2 0.020
taxis GO:0042330 109 0.020
Human Mouse
striated muscle tissue development GO:0014706 110 0.019
stem cell maintenance GO:0019827 4 0.019
regulation of protein ubiquitination GO:0031396 3 0.019
positive regulation of protein kinase b signaling GO:0051897 1 0.019
Human
cardiac atrium development GO:0003230 4 0.019
response to glucose GO:0009749 3 0.019
Human
regulation of stem cell differentiation GO:2000736 4 0.019
forebrain development GO:0030900 96 0.018
response to xenobiotic stimulus GO:0009410 45 0.018
protein phosphorylation GO:0006468 47 0.018
Human
protein dephosphorylation GO:0006470 3 0.018
cytosolic calcium ion transport GO:0060401 3 0.018
dopaminergic neuron differentiation GO:0071542 14 0.018
cytokinesis GO:0000910 3 0.018
embryonic heart tube development GO:0035050 133 0.018
non canonical wnt signaling pathway GO:0035567 13 0.018
multicellular organismal macromolecule metabolic process GO:0044259 2 0.018
response to vitamin GO:0033273 3 0.018
cell fate specification GO:0001708 68 0.018
mucopolysaccharide metabolic process GO:1903510 2 0.017
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.017
negative regulation of mesodermal cell fate specification GO:0042662 3 0.017
cellular protein catabolic process GO:0044257 4 0.017
digestive tract development GO:0048565 265 0.017
sulfur compound metabolic process GO:0006790 13 0.017
positive regulation of cellular biosynthetic process GO:0031328 68 0.017
Human
muscle structure development GO:0061061 196 0.017
Fly
organonitrogen compound biosynthetic process GO:1901566 47 0.017
regulation of nucleotide catabolic process GO:0030811 2 0.017
protein modification process GO:0036211 100 0.017
Human
locomotion GO:0040011 313 0.017
Human Mouse
ear development GO:0043583 127 0.017
macromolecule localization GO:0033036 54 0.017
Human
regulation of bmp signaling pathway GO:0030510 39 0.017
retina development in camera type eye GO:0060041 146 0.017
regulation of biological quality GO:0065008 263 0.017
Human
pigmentation GO:0043473 85 0.017
urogenital system development GO:0001655 97 0.017
synaptic growth at neuromuscular junction GO:0051124 2 0.017
negative regulation of response to stimulus GO:0048585 104 0.016
Human
tube closure GO:0060606 1 0.016
neuroblast fate determination GO:0007400 1 0.016
wound healing GO:0042060 90 0.016
Human
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.016
response to organic cyclic compound GO:0014070 51 0.016
multicellular organismal metabolic process GO:0044236 2 0.016
single organism metabolic process GO:0044710 217 0.016
Human
cardiac ventricle development GO:0003231 9 0.016
lateral line system development GO:0048925 76 0.016
intracellular signal transduction GO:0035556 85 0.016
Human
cellular macromolecule localization GO:0070727 21 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.015
protein acylation GO:0043543 3 0.015
neural retina development GO:0003407 49 0.015
cellular response to lipid GO:0071396 39 0.015
muscle cell fate determination GO:0007521 1 0.015
small gtpase mediated signal transduction GO:0007264 8 0.015
regulation of cell motility GO:2000145 46 0.015
Human Mouse
modification dependent protein catabolic process GO:0019941 3 0.015
negative regulation of protein processing GO:0010955 10 0.015
Human
positive regulation of catabolic process GO:0009896 4 0.015
organelle organization GO:0006996 227 0.015
ubiquitin dependent protein catabolic process GO:0006511 3 0.015
developmental maturation GO:0021700 34 0.014
stem cell fate commitment GO:0048865 1 0.014
response to hormone GO:0009725 48 0.014
negative regulation of catalytic activity GO:0043086 21 0.014
Human
stem cell differentiation GO:0048863 117 0.014
cardiac chamber development GO:0003205 19 0.014
cell cycle GO:0007049 93 0.014
Human
positive regulation of cytokine production GO:0001819 2 0.014
Human
positive regulation of cellular component biogenesis GO:0044089 3 0.014
regulation of gtpase activity GO:0043087 2 0.014
posterior lateral line system development GO:0048915 46 0.014
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.014
cellular response to radiation GO:0071478 4 0.014
response to external biotic stimulus GO:0043207 97 0.014
regulation of cell death GO:0010941 103 0.014
Human
aminoglycan metabolic process GO:0006022 9 0.014
regulation of cellular component movement GO:0051270 55 0.014
Human Mouse
heart looping GO:0001947 94 0.014
regulation of canonical wnt signaling pathway GO:0060828 34 0.014
establishment of localization in cell GO:0051649 77 0.014
negative regulation of reproductive process GO:2000242 3 0.013
nuclear division GO:0000280 23 0.013
mesenchymal cell proliferation GO:0010463 1 0.013
carbohydrate biosynthetic process GO:0016051 1 0.013
regulation of growth GO:0040008 42 0.013
cellular component assembly GO:0022607 170 0.013
muscle fiber development GO:0048747 52 0.013
positive regulation of apoptotic signaling pathway GO:2001235 1 0.013
Human
glial cell proliferation GO:0014009 4 0.013
neuron projection guidance GO:0097485 86 0.013
fin morphogenesis GO:0033334 53 0.013
regulation of response to stress GO:0080134 36 0.013
Human
chondroitin sulfate proteoglycan metabolic process GO:0050654 8 0.013
regulation of epithelial to mesenchymal transition GO:0010717 3 0.013
membrane invagination GO:0010324 1 0.013
Human
spermatid differentiation GO:0048515 2 0.013
glucose homeostasis GO:0042593 1 0.013
response to hexose GO:0009746 3 0.013
Human
regulation of cell substrate adhesion GO:0010810 1 0.013
Human Mouse
reproductive process GO:0022414 40 0.013
regulation of apoptotic process GO:0042981 98 0.013
Human
axonogenesis GO:0007409 152 0.013
regulation of developmental process GO:0050793 247 0.013
Human Mouse
wnt signaling pathway planar cell polarity pathway GO:0060071 4 0.013
epithelial to mesenchymal transition GO:0001837 21 0.013
protein localization GO:0008104 40 0.013
positive regulation of rna biosynthetic process GO:1902680 57 0.013
regulation of cellular component organization GO:0051128 86 0.012
cellular response to growth factor stimulus GO:0071363 39 0.012
Human Mouse
positive regulation of gene expression GO:0010628 71 0.012
Human
germ line stem cell maintenance GO:0030718 2 0.012
regulation of autophagy GO:0010506 3 0.012
negative regulation of mapk cascade GO:0043409 4 0.012
glycosaminoglycan metabolic process GO:0030203 9 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.012
Human
posttranscriptional regulation of gene expression GO:0010608 14 0.012
Human
nucleobase containing small molecule metabolic process GO:0055086 32 0.012
Human
response to uv GO:0009411 3 0.012
cell projection assembly GO:0030031 64 0.012
regulation of peptidase activity GO:0052547 23 0.012
Human
regulation of hormone secretion GO:0046883 2 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
regulation of tube size GO:0035150 2 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.012
actin filament based process GO:0030029 64 0.012
single organism cellular localization GO:1902580 46 0.012
negative regulation of stem cell differentiation GO:2000737 2 0.012
gtp metabolic process GO:0046039 4 0.012
cell proliferation GO:0008283 80 0.012
Human Mouse
regulation of mesenchymal cell proliferation GO:0010464 1 0.012
muscle tissue development GO:0060537 110 0.012
bone remodeling GO:0046849 2 0.012
response to other organism GO:0051707 97 0.011
negative regulation of rna biosynthetic process GO:1902679 45 0.011
regulation of cell development GO:0060284 100 0.011
extrinsic apoptotic signaling pathway GO:0097191 3 0.011
Human
regulation of mitotic cell cycle GO:0007346 25 0.011
trabecula formation GO:0060343 2 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.011
epidermis development GO:0008544 48 0.011
regulation of protein catabolic process GO:0042176 1 0.011
oocyte maturation GO:0001556 4 0.011
cell division GO:0051301 20 0.011
developmental growth involved in morphogenesis GO:0060560 86 0.011
Mouse
positive regulation of secretion GO:0051047 1 0.011
septum transversum development GO:0003343 4 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.011
embryonic eye morphogenesis GO:0048048 30 0.011
endodermal cell differentiation GO:0035987 19 0.011
endoderm development GO:0007492 49 0.011
negative regulation of multi organism process GO:0043901 3 0.011
regulation of cell proliferation GO:0042127 37 0.011
Human Mouse
muscle cell differentiation GO:0042692 139 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.011
Human
neuron development GO:0048666 262 0.011
phagocytosis engulfment GO:0006911 1 0.011
Human
cardiocyte differentiation GO:0035051 44 0.011
regulation of carbohydrate biosynthetic process GO:0043255 1 0.011
regulation of molecular function GO:0065009 70 0.011
Human
sensory system development GO:0048880 76 0.011
oocyte differentiation GO:0009994 14 0.011
chemical homeostasis GO:0048878 49 0.011
skin development GO:0043588 54 0.011
fin development GO:0033333 77 0.011
meiotic cell cycle process GO:1903046 3 0.011
cell growth GO:0016049 57 0.011
secondary metabolic process GO:0019748 3 0.011
peptidyl serine phosphorylation GO:0018105 1 0.011
cell cycle g1 s phase transition GO:0044843 1 0.011

thbs1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.113
musculoskeletal system disease DOID:17 0 0.051
nervous system disease DOID:863 0 0.040
disease of cellular proliferation DOID:14566 0 0.030
connective tissue disease DOID:65 0 0.029
bone development disease DOID:0080006 0 0.027
bone disease DOID:0080001 0 0.027
immune system disease DOID:2914 0 0.015
cancer DOID:162 0 0.012
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011