Danio rerio

0 known processes

thoc2

THO complex 2

(Aliases: fb73e08,wu:fb73e08,wu:fd21d11,Tho2,THO,si:bz1o18.2,fd21d11)

thoc2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of biosynthetic process GO:0009889 250 0.330
regulation of metabolic process GO:0019222 359 0.313
gene expression GO:0010467 252 0.265
organic cyclic compound metabolic process GO:1901360 301 0.263
cellular aromatic compound metabolic process GO:0006725 295 0.260
cellular macromolecule biosynthetic process GO:0034645 224 0.251
cellular macromolecule metabolic process GO:0044260 391 0.249
larval development GO:0002164 2 0.241
Worm
regulation of rna metabolic process GO:0051252 224 0.240
cellular biosynthetic process GO:0044249 286 0.237
nucleic acid metabolic process GO:0090304 244 0.237
organelle organization GO:0006996 227 0.236
Worm
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.231
heterocycle metabolic process GO:0046483 290 0.225
rna metabolic process GO:0016070 219 0.216
regulation of macromolecule biosynthetic process GO:0010556 225 0.205
biosynthetic process GO:0009058 294 0.166
heterocycle biosynthetic process GO:0018130 215 0.163
regulation of cellular biosynthetic process GO:0031326 245 0.157
aromatic compound biosynthetic process GO:0019438 217 0.157
cellular nitrogen compound metabolic process GO:0034641 290 0.156
nitrogen compound metabolic process GO:0006807 319 0.152
macromolecule biosynthetic process GO:0009059 227 0.144
regulation of transcription dna templated GO:0006355 213 0.140
regulation of primary metabolic process GO:0080090 311 0.139
regulation of gene expression GO:0010468 265 0.134
regulation of macromolecule metabolic process GO:0060255 317 0.122
meiotic nuclear division GO:0007126 4 0.111
Worm
autophagy GO:0006914 4 0.107
organic substance biosynthetic process GO:1901576 289 0.107
regulation of rna biosynthetic process GO:2001141 213 0.097
nucleobase containing compound biosynthetic process GO:0034654 205 0.095
negative regulation of cellular process GO:0048523 283 0.094
cellular nitrogen compound biosynthetic process GO:0044271 218 0.094
rna biosynthetic process GO:0032774 181 0.091
organic cyclic compound biosynthetic process GO:1901362 223 0.089
single organism organelle organization GO:1902589 199 0.084
nucleic acid templated transcription GO:0097659 181 0.081
establishment of protein localization to organelle GO:0072594 4 0.072
regulation of nucleic acid templated transcription GO:1903506 213 0.067
nucleobase containing compound metabolic process GO:0006139 274 0.066
stem cell maintenance GO:0019827 4 0.062
establishment of apical basal cell polarity GO:0035089 2 0.059
regulation of nitrogen compound metabolic process GO:0051171 251 0.059
tube morphogenesis GO:0035239 349 0.051
transcription from rna polymerase ii promoter GO:0006366 80 0.049
positive regulation of biological process GO:0048518 253 0.048
cellular response to lipopolysaccharide GO:0071222 3 0.046
transcription dna templated GO:0006351 181 0.046
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.045
negative regulation of macromolecule metabolic process GO:0010605 76 0.045
regulation of protein catabolic process GO:0042176 1 0.045
protein demethylation GO:0006482 2 0.044
aging GO:0007568 2 0.044
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.043
positive regulation of protein complex assembly GO:0031334 2 0.041
negative regulation of metabolic process GO:0009892 86 0.041
cell proliferation GO:0008283 80 0.040
regulation of protein transport GO:0051223 3 0.040
macromolecular complex subunit organization GO:0043933 74 0.038
actin polymerization or depolymerization GO:0008154 2 0.038
nuclear transport GO:0051169 4 0.036
circadian sleep wake cycle GO:0042745 2 0.036
regulation of jak stat cascade GO:0046425 3 0.036
negative regulation of cellular metabolic process GO:0031324 77 0.036
response to uv GO:0009411 3 0.036
positive regulation of map kinase activity GO:0043406 3 0.035
cellular response to molecule of bacterial origin GO:0071219 3 0.035
regulation of cell cycle GO:0051726 52 0.035
cell cycle g1 s phase transition GO:0044843 1 0.034
stem cell proliferation GO:0072089 4 0.034
regulation of cellular metabolic process GO:0031323 320 0.033
regulation of protein complex assembly GO:0043254 3 0.033
negative regulation of rna metabolic process GO:0051253 48 0.032
regulation of meiotic cell cycle GO:0051445 1 0.032
regulation of autophagy GO:0010506 3 0.032
regulation of cytokine production GO:0001817 3 0.031
internal protein amino acid acetylation GO:0006475 2 0.031
transmembrane transport GO:0055085 120 0.031
chromatin organization GO:0006325 22 0.030
localization within membrane GO:0051668 1 0.030
development of primary female sexual characteristics GO:0046545 4 0.028
regulation of response to stimulus GO:0048583 269 0.028
regulation of multicellular organism growth GO:0040014 4 0.028
response to stress GO:0006950 263 0.027
generation of neurons GO:0048699 385 0.027
protein import into nucleus GO:0006606 3 0.027
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.027
positive regulation of cell activation GO:0050867 1 0.027
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.027
positive regulation of catabolic process GO:0009896 4 0.026
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.026
single organism metabolic process GO:0044710 217 0.026
chloride transmembrane transport GO:1902476 4 0.026
positive regulation of cellular component biogenesis GO:0044089 3 0.026
chromosome organization GO:0051276 31 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.026
negative regulation of gene expression GO:0010629 65 0.025
regulation of jun kinase activity GO:0043506 3 0.025
cellular response to radiation GO:0071478 4 0.025
carbohydrate homeostasis GO:0033500 1 0.025
cellular response to biotic stimulus GO:0071216 3 0.025
cell cycle process GO:0022402 53 0.025
Worm
transport GO:0006810 220 0.024
signal transduction GO:0007165 455 0.024
protein metabolic process GO:0019538 183 0.024
rna transport GO:0050658 2 0.024
head development GO:0060322 303 0.023
antimicrobial humoral response GO:0019730 2 0.022
protein acetylation GO:0006473 2 0.022
positive regulation of secretion by cell GO:1903532 1 0.022
regulation of cytoplasmic transport GO:1903649 4 0.022
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.022
regulation of organelle organization GO:0033043 29 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.022
positive regulation of cellular biosynthetic process GO:0031328 68 0.022
positive regulation of cell cycle GO:0045787 3 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.022
negative regulation of biosynthetic process GO:0009890 55 0.022
somatic stem cell maintenance GO:0035019 1 0.021
dna templated transcription initiation GO:0006352 1 0.021
circadian sleep wake cycle sleep GO:0050802 1 0.021
regulation of mitotic cell cycle GO:0007346 25 0.021
regulation of nucleocytoplasmic transport GO:0046822 2 0.021
regulation of synapse assembly GO:0051963 3 0.021
regulation of postsynaptic membrane potential GO:0060078 1 0.020
regulation of cell activation GO:0050865 1 0.020
negative regulation of rna biosynthetic process GO:1902679 45 0.020
spermatid differentiation GO:0048515 2 0.020
positive regulation of cellular catabolic process GO:0031331 3 0.020
chordate embryonic development GO:0043009 271 0.020
neurotransmitter secretion GO:0007269 2 0.020
regulation of glial cell differentiation GO:0045685 4 0.020
establishment of localization GO:0051234 244 0.020
positive regulation of stem cell proliferation GO:2000648 1 0.019
epithelial cell differentiation GO:0030855 116 0.019
regionalization GO:0003002 274 0.019
protein complex disassembly GO:0043241 1 0.019
positive regulation of rna metabolic process GO:0051254 59 0.019
negative regulation of synapse assembly GO:0051964 2 0.019
positive regulation of immune effector process GO:0002699 3 0.019
single organism nuclear import GO:1902593 3 0.019
response to external stimulus GO:0009605 264 0.018
positive regulation of transport GO:0051050 2 0.018
cellular response to external stimulus GO:0071496 2 0.018
hormone transport GO:0009914 2 0.018
cellular protein complex disassembly GO:0043624 1 0.018
synaptic target recognition GO:0008039 1 0.018
cellular protein metabolic process GO:0044267 129 0.018
neuronal action potential GO:0019228 18 0.018
cellular amide metabolic process GO:0043603 4 0.017
immune system development GO:0002520 191 0.017
cellular response to extracellular stimulus GO:0031668 2 0.017
female gonad development GO:0008585 4 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
regulation of dna replication GO:0006275 3 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.017
cell part morphogenesis GO:0032990 246 0.017
rna localization GO:0006403 4 0.017
specification of symmetry GO:0009799 204 0.017
regulation of intracellular protein transport GO:0033157 3 0.017
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.017
protein import GO:0017038 3 0.017
cytoskeleton organization GO:0007010 96 0.016
circadian sleep wake cycle process GO:0022410 2 0.016
neuroblast proliferation GO:0007405 2 0.016
transmission of nerve impulse GO:0019226 19 0.016
peptide transport GO:0015833 1 0.016
cellular response to nutrient levels GO:0031669 2 0.016
positive regulation of secretion GO:0051047 1 0.016
regulation of signaling GO:0023051 235 0.016
synaptic growth at neuromuscular junction GO:0051124 2 0.016
regulation of establishment of protein localization GO:0070201 4 0.016
macromolecular complex disassembly GO:0032984 1 0.015
positive regulation of jnk cascade GO:0046330 3 0.015
spermatid development GO:0007286 2 0.015
cellular component disassembly GO:0022411 1 0.015
programmed cell death GO:0012501 119 0.015
Worm
negative regulation of gliogenesis GO:0014014 1 0.015
cell aging GO:0007569 2 0.015
positive regulation of epithelial cell proliferation GO:0050679 1 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.015
positive regulation of rna biosynthetic process GO:1902680 57 0.015
regulation of synapse organization GO:0050807 3 0.015
organelle assembly GO:0070925 110 0.015
histone demethylation GO:0016577 2 0.015
nuclear import GO:0051170 3 0.015
regulation of protein localization to nucleus GO:1900180 2 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.015
positive regulation of jun kinase activity GO:0043507 2 0.015
neuroblast differentiation GO:0014016 1 0.015
mitotic g2 m transition checkpoint GO:0044818 3 0.015
cell surface receptor signaling pathway GO:0007166 325 0.014
maintenance of location GO:0051235 4 0.014
internal peptidyl lysine acetylation GO:0018393 2 0.014
negative regulation of kinase activity GO:0033673 4 0.014
somatic muscle development GO:0007525 4 0.014
regulation of protein import into nucleus GO:0042306 2 0.014
defense response to fungus GO:0050832 2 0.014
macromolecule modification GO:0043412 111 0.014
g1 s transition of mitotic cell cycle GO:0000082 1 0.014
nucleocytoplasmic transport GO:0006913 4 0.014
endosomal transport GO:0016197 2 0.014
positive regulation of biosynthetic process GO:0009891 68 0.014
epithelial cell development GO:0002064 42 0.014
single organism transport GO:0044765 206 0.014
odontogenesis of dentin containing tooth GO:0042475 1 0.013
mrna stabilization GO:0048255 4 0.013
negative regulation of chromatin modification GO:1903309 1 0.013
stem cell differentiation GO:0048863 117 0.013
regulation of neurological system process GO:0031644 2 0.013
establishment of monopolar cell polarity GO:0061162 2 0.013
regulation of biological quality GO:0065008 263 0.013
peptidyl lysine acetylation GO:0018394 2 0.013
regulation of histone methylation GO:0031060 3 0.013
response to drug GO:0042493 3 0.013
cellular amine metabolic process GO:0044106 2 0.013
positive regulation of apoptotic signaling pathway GO:2001235 1 0.013
protein acylation GO:0043543 3 0.013
regulation of protein metabolic process GO:0051246 56 0.013
brain development GO:0007420 293 0.013
locomotion GO:0040011 313 0.013
Worm
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.012
regulation of establishment of planar polarity GO:0090175 4 0.012
activation of mapk activity GO:0000187 3 0.012
stem cell fate commitment GO:0048865 1 0.012
protein localization to nucleus GO:0034504 3 0.012
response to external biotic stimulus GO:0043207 97 0.012
regulation of mrna splicing via spliceosome GO:0048024 3 0.012
multicellular organism growth GO:0035264 4 0.012
cellular response to dna damage stimulus GO:0006974 24 0.012
adherens junction organization GO:0034332 4 0.012
regulation of oligodendrocyte differentiation GO:0048713 1 0.012
regulation of response to nutrient levels GO:0032107 1 0.012
enzyme linked receptor protein signaling pathway GO:0007167 106 0.012
somite development GO:0061053 96 0.012
regulation of protein ubiquitination GO:0031396 3 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.011
mrna metabolic process GO:0016071 20 0.011
mitotic dna integrity checkpoint GO:0044774 4 0.011
protein polymerization GO:0051258 4 0.011
axis elongation GO:0003401 31 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
nuclear export GO:0051168 1 0.011
glucose homeostasis GO:0042593 1 0.011
type i interferon production GO:0032606 2 0.011
regulation of photoreceptor cell differentiation GO:0046532 2 0.011
mitotic cell cycle GO:0000278 64 0.011
regulation of cellular ketone metabolic process GO:0010565 7 0.011
single organism localization GO:1902578 225 0.011
positive regulation of nucleic acid templated transcription GO:1903508 57 0.011
primary neural tube formation GO:0014020 1 0.011
locomotor rhythm GO:0045475 3 0.011
hormone secretion GO:0046879 2 0.011
cellular response to starvation GO:0009267 1 0.011
tube closure GO:0060606 1 0.011
nucleobase containing compound transport GO:0015931 2 0.011
positive regulation of macromolecule metabolic process GO:0010604 93 0.011
neuron differentiation GO:0030182 353 0.011
modification dependent macromolecule catabolic process GO:0043632 3 0.011
cellular protein catabolic process GO:0044257 4 0.011
response to corticosteroid GO:0031960 1 0.011
carboxylic acid metabolic process GO:0019752 22 0.011
proteolysis GO:0006508 38 0.011
regulation of innate immune response GO:0045088 11 0.010
regulation of hormone secretion GO:0046883 2 0.010
regulation of cell communication GO:0010646 232 0.010
regulation of programmed cell death GO:0043067 101 0.010
death GO:0016265 121 0.010
Worm
positive regulation of cytokine production GO:0001819 2 0.010
regulation of skeletal muscle fiber development GO:0048742 2 0.010
establishment of mitotic spindle localization GO:0040001 12 0.010
regulation of cellular amine metabolic process GO:0033238 0 0.010
histone lysine demethylation GO:0070076 2 0.010
multicellular organismal signaling GO:0035637 22 0.010
intracellular mrna localization GO:0008298 1 0.010
regulation of protein targeting GO:1903533 2 0.010
digestive system development GO:0055123 289 0.010
chemotaxis GO:0006935 104 0.010
polyol metabolic process GO:0019751 1 0.010
renal system vasculature development GO:0061437 2 0.010
cellular localization GO:0051641 97 0.010
embryo development ending in birth or egg hatching GO:0009792 271 0.010
Worm
long chain fatty acid metabolic process GO:0001676 1 0.010

thoc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org