Danio rerio

0 known processes

thoc3

THO complex 3

(Aliases: zgc:100815)

thoc3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular nitrogen compound metabolic process GO:0034641 290 0.421
cellular nitrogen compound biosynthetic process GO:0044271 218 0.266
gene expression GO:0010467 252 0.206
Human
cellular macromolecule metabolic process GO:0044260 391 0.190
cellular aromatic compound metabolic process GO:0006725 295 0.185
heterocycle metabolic process GO:0046483 290 0.171
biosynthetic process GO:0009058 294 0.138
embryo development ending in birth or egg hatching GO:0009792 271 0.133
nucleobase containing compound metabolic process GO:0006139 274 0.132
rna metabolic process GO:0016070 219 0.126
nitrogen compound metabolic process GO:0006807 319 0.124
organic cyclic compound biosynthetic process GO:1901362 223 0.114
negative regulation of biological process GO:0048519 304 0.101
positive regulation of cellular process GO:0048522 201 0.101
single organism metabolic process GO:0044710 217 0.097
nucleobase containing compound biosynthetic process GO:0034654 205 0.088
cellular macromolecule biosynthetic process GO:0034645 224 0.086
organelle organization GO:0006996 227 0.078
aromatic compound biosynthetic process GO:0019438 217 0.075
cellular biosynthetic process GO:0044249 286 0.071
intra s dna damage checkpoint GO:0031573 1 0.069
negative regulation of signal transduction by p53 class mediator GO:1901797 8 0.068
organic cyclic compound metabolic process GO:1901360 301 0.067
organic substance biosynthetic process GO:1901576 289 0.065
regulation of signal transduction GO:0009966 225 0.063
negative regulation of response to dna damage stimulus GO:2001021 3 0.063
negative regulation of cellular process GO:0048523 283 0.062
regulation of metabolic process GO:0019222 359 0.061
response to monosaccharide GO:0034284 3 0.059
regulation of signal transduction by p53 class mediator GO:1901796 9 0.058
response to hexose GO:0009746 3 0.056
regulation of primary metabolic process GO:0080090 311 0.055
regulation of signaling GO:0023051 235 0.054
nuclear transport GO:0051169 4 0.051
Human
protein complex localization GO:0031503 1 0.048
g1 s transition of mitotic cell cycle GO:0000082 1 0.047
nucleic acid templated transcription GO:0097659 181 0.047
regulation of response to stimulus GO:0048583 269 0.046
nuclear division GO:0000280 23 0.046
larval development GO:0002164 2 0.044
protein metabolic process GO:0019538 183 0.043
macromolecule biosynthetic process GO:0009059 227 0.043
transcription dna templated GO:0006351 181 0.043
signal transduction GO:0007165 455 0.042
cellular carbohydrate metabolic process GO:0044262 4 0.042
cell cycle g1 s phase transition GO:0044843 1 0.041
transcription from rna polymerase ii promoter GO:0006366 80 0.041
immune system development GO:0002520 191 0.039
response to carbohydrate GO:0009743 3 0.039
regulation of establishment of protein localization GO:0070201 4 0.039
intracellular signal transduction GO:0035556 85 0.039
regulation of gene expression GO:0010468 265 0.038
response to stress GO:0006950 263 0.038
i kappab kinase nf kappab signaling GO:0007249 4 0.038
organonitrogen compound metabolic process GO:1901564 74 0.038
response to glucose GO:0009749 3 0.037
signal transduction by p53 class mediator GO:0072331 13 0.037
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.036
regulation of nucleocytoplasmic transport GO:0046822 2 0.036
glucose homeostasis GO:0042593 1 0.036
mrna metabolic process GO:0016071 20 0.036
rna biosynthetic process GO:0032774 181 0.035
regulation of cellular metabolic process GO:0031323 320 0.035
negative regulation of protein transport GO:0051224 3 0.034
regulation of cell communication GO:0010646 232 0.034
single organism organelle organization GO:1902589 199 0.032
nucleic acid metabolic process GO:0090304 244 0.032
positive regulation of transport GO:0051050 2 0.032
regulation of macromolecule metabolic process GO:0060255 317 0.031
regulation of protein transport GO:0051223 3 0.031
hematopoietic or lymphoid organ development GO:0048534 191 0.031
positive regulation of catabolic process GO:0009896 4 0.031
negative regulation of nuclear division GO:0051784 3 0.031
cellular response to stress GO:0033554 62 0.030
regulation of mitochondrion organization GO:0010821 1 0.029
cellular component assembly GO:0022607 170 0.029
rna 3 end processing GO:0031123 2 0.029
positive regulation of cell cycle GO:0045787 3 0.029
regulation of macromolecule biosynthetic process GO:0010556 225 0.028
cellular ketone metabolic process GO:0042180 11 0.028
cellular response to extracellular stimulus GO:0031668 2 0.028
heterocycle biosynthetic process GO:0018130 215 0.028
hematopoietic stem cell migration GO:0035701 4 0.027
regulation of cytoplasmic transport GO:1903649 4 0.027
negative regulation of biosynthetic process GO:0009890 55 0.027
small molecule metabolic process GO:0044281 77 0.027
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.027
negative regulation of gene expression GO:0010629 65 0.026
central nervous system development GO:0007417 387 0.026
regulation of protein targeting GO:1903533 2 0.026
mitochondrion organization GO:0007005 4 0.026
mitotic cell cycle GO:0000278 64 0.026
regulation of cellular biosynthetic process GO:0031326 245 0.026
regulation of apoptotic process GO:0042981 98 0.026
negative regulation of mapk cascade GO:0043409 4 0.025
negative regulation of metabolic process GO:0009892 86 0.025
single organism nuclear import GO:1902593 3 0.025
meiotic nuclear division GO:0007126 4 0.025
regulation of protein localization to nucleus GO:1900180 2 0.025
carbohydrate homeostasis GO:0033500 1 0.024
regulation of cellular ketone metabolic process GO:0010565 7 0.023
synaptic vesicle localization GO:0097479 1 0.023
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.023
regulation of biological quality GO:0065008 263 0.023
establishment of protein localization to organelle GO:0072594 4 0.023
cellular response to dna damage stimulus GO:0006974 24 0.022
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.022
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.022
negative regulation of signal transduction GO:0009968 94 0.022
regulation of intracellular protein transport GO:0033157 3 0.022
mitotic dna damage checkpoint GO:0044773 4 0.021
maintenance of location GO:0051235 4 0.021
determination of bilateral symmetry GO:0009855 204 0.020
regulation of nitrogen compound metabolic process GO:0051171 251 0.020
establishment of protein localization to plasma membrane GO:0090002 1 0.020
negative regulation of protein localization to nucleus GO:1900181 2 0.020
localization within membrane GO:0051668 1 0.020
specification of symmetry GO:0009799 204 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.019
negative regulation of response to stimulus GO:0048585 104 0.019
regulation of cellular amine metabolic process GO:0033238 0 0.019
regulation of response to stress GO:0080134 36 0.018
protein secretion GO:0009306 1 0.018
establishment of localization GO:0051234 244 0.018
Human
pore complex assembly GO:0046931 2 0.018
cell cycle g2 m phase transition GO:0044839 4 0.018
mitotic dna integrity checkpoint GO:0044774 4 0.018
regulation of biosynthetic process GO:0009889 250 0.018
negative regulation of macromolecule metabolic process GO:0010605 76 0.018
positive regulation of cellular catabolic process GO:0031331 3 0.018
positive regulation of biological process GO:0048518 253 0.018
peptide transport GO:0015833 1 0.018
phagocytosis GO:0006909 3 0.018
cellular protein metabolic process GO:0044267 129 0.018
cellular response to external stimulus GO:0071496 2 0.018
protein import into nucleus GO:0006606 3 0.018
protein localization to plasma membrane GO:0072659 1 0.017
adult behavior GO:0030534 2 0.017
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.017
regulation of programmed cell death GO:0043067 101 0.017
negative regulation of cellular metabolic process GO:0031324 77 0.017
protein targeting to nucleus GO:0044744 3 0.017
macromolecule modification GO:0043412 111 0.017
nucleocytoplasmic transport GO:0006913 4 0.017
Human
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
homeostatic process GO:0042592 142 0.017
negative regulation of programmed cell death GO:0043069 58 0.017
regulation of rna metabolic process GO:0051252 224 0.016
nuclear import GO:0051170 3 0.016
macromolecular complex assembly GO:0065003 35 0.016
cellular amino acid metabolic process GO:0006520 7 0.016
negative regulation of signaling GO:0023057 96 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.016
meiotic cell cycle process GO:1903046 3 0.016
reactive oxygen species biosynthetic process GO:1903409 1 0.016
single organism cellular localization GO:1902580 46 0.016
cellular component movement GO:0006928 335 0.015
organism emergence from protective structure GO:0071684 4 0.015
embryonic hemopoiesis GO:0035162 53 0.015
aging GO:0007568 2 0.015
protein modification process GO:0036211 100 0.015
intracellular estrogen receptor signaling pathway GO:0030520 3 0.015
regulation of autophagy GO:0010506 3 0.015
rna processing GO:0006396 25 0.015
g2 m transition of mitotic cell cycle GO:0000086 4 0.015
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.015
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.015
cellular response to oxygen levels GO:0071453 1 0.014
apoptotic process GO:0006915 116 0.014
regulation of protein import into nucleus GO:0042306 2 0.014
positive regulation of macromolecule metabolic process GO:0010604 93 0.014
ribosome assembly GO:0042255 1 0.014
protein import GO:0017038 3 0.014
negative regulation of intracellular transport GO:0032387 3 0.014
positive regulation of carbohydrate metabolic process GO:0045913 1 0.014
response to abiotic stimulus GO:0009628 122 0.014
mitotic cell cycle process GO:1903047 48 0.014
regulation of meiotic cell cycle GO:0051445 1 0.014
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.014
brain development GO:0007420 293 0.014
regulation of nucleic acid templated transcription GO:1903506 213 0.013
regulation of protein ubiquitination GO:0031396 3 0.013
establishment of rna localization GO:0051236 3 0.013
Human
cell cycle phase transition GO:0044770 9 0.013
hemopoiesis GO:0030097 183 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.013
generation of neurons GO:0048699 385 0.013
carbohydrate biosynthetic process GO:0016051 1 0.013
regulation of carbohydrate biosynthetic process GO:0043255 1 0.013
regulation of transcription dna templated GO:0006355 213 0.013
positive regulation of biosynthetic process GO:0009891 68 0.013
rna modification GO:0009451 2 0.013
regulation of dna damage response signal transduction by p53 class mediator GO:0043516 4 0.013
cell migration GO:0016477 237 0.013
negative regulation of rna metabolic process GO:0051253 48 0.013
cell cycle process GO:0022402 53 0.013
regulation of exocytosis GO:0017157 1 0.013
regulation of cell activation GO:0050865 1 0.013
single organism transport GO:0044765 206 0.013
cellular response to chemical stimulus GO:0070887 157 0.012
regulation of synaptic plasticity GO:0048167 1 0.012
synaptic vesicle transport GO:0048489 1 0.012
purine nucleoside monophosphate catabolic process GO:0009128 4 0.012
negative regulation of intracellular signal transduction GO:1902532 22 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.012
neurotransmitter transport GO:0006836 2 0.012
ribonucleoside biosynthetic process GO:0042455 2 0.012
regulation of intracellular signal transduction GO:1902531 57 0.012
regulation of hormone secretion GO:0046883 2 0.012
membrane fusion GO:0061025 2 0.012
autophagy GO:0006914 4 0.012
cell cycle GO:0007049 93 0.012
regulation of rna biosynthetic process GO:2001141 213 0.012
guanosine containing compound catabolic process GO:1901069 2 0.012
microtubule organizing center organization GO:0031023 1 0.012
organic substance transport GO:0071702 58 0.012
Human
response to external stimulus GO:0009605 264 0.011
hatching GO:0035188 4 0.011
energy reserve metabolic process GO:0006112 2 0.011
mitotic cell cycle embryonic GO:0045448 2 0.011
ncrna catabolic process GO:0034661 1 0.011
macromolecular complex subunit organization GO:0043933 74 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.011
positive regulation of response to stimulus GO:0048584 80 0.011
protein phosphorylation GO:0006468 47 0.011
gtp metabolic process GO:0046039 4 0.011
macromolecule localization GO:0033036 54 0.011
Human
establishment of synaptic vesicle localization GO:0097480 1 0.011
cellular component biogenesis GO:0044085 178 0.011
guanosine containing compound metabolic process GO:1901068 4 0.011
gtp catabolic process GO:0006184 2 0.011
regulation of cell cycle GO:0051726 52 0.011
organelle assembly GO:0070925 110 0.011
regulation of mitotic cell cycle GO:0007346 25 0.011
cellular protein localization GO:0034613 20 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
regulation of dna recombination GO:0000018 2 0.011
single organism localization GO:1902578 225 0.011
cellular macromolecular complex assembly GO:0034622 24 0.011
response to uv GO:0009411 3 0.011
negative regulation of cell death GO:0060548 60 0.011
phosphorus metabolic process GO:0006793 109 0.011
organic acid metabolic process GO:0006082 31 0.011
cellular protein complex localization GO:0034629 1 0.010
catecholamine metabolic process GO:0006584 2 0.010
negative regulation of apoptotic process GO:0043066 55 0.010
regionalization GO:0003002 274 0.010
peptidyl lysine acetylation GO:0018394 2 0.010
heart development GO:0007507 313 0.010
mitotic nuclear division GO:0007067 18 0.010
negative regulation of protein phosphorylation GO:0001933 4 0.010
mitotic g2 dna damage checkpoint GO:0007095 3 0.010
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.010
embryonic organ development GO:0048568 381 0.010
g2 dna damage checkpoint GO:0031572 3 0.010
nitric oxide biosynthetic process GO:0006809 2 0.010
negative regulation of rna biosynthetic process GO:1902679 45 0.010
non recombinational repair GO:0000726 2 0.010
protein localization to nucleus GO:0034504 3 0.010
protein complex disassembly GO:0043241 1 0.010

thoc3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.011