Danio rerio

96 known processes

thraa

thyroid hormone receptor alpha a

(Aliases: thral,nr1a1,thra,tra,tra1,TR[a]1,wu:fb59g07)

thraa biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
establishment of protein localization to organelle GO:0072594 4 0.337
Mouse
regulation of signal transduction GO:0009966 225 0.268
Zebrafish Mouse
circadian regulation of gene expression GO:0032922 8 0.250
Zebrafish
nucleocytoplasmic transport GO:0006913 4 0.239
Mouse
nuclear transport GO:0051169 4 0.238
Mouse
protein targeting to nucleus GO:0044744 3 0.214
Mouse
protein localization to nucleus GO:0034504 3 0.188
Mouse
cognition GO:0050890 1 0.183
Mouse
maintenance of location GO:0051235 4 0.171
Mouse
single organism transport GO:0044765 206 0.169
Mouse
head development GO:0060322 303 0.160
Zebrafish Rat
gland development GO:0048732 143 0.158
Zebrafish Mouse Rat
generation of neurons GO:0048699 385 0.153
Zebrafish
regulation of primary metabolic process GO:0080090 311 0.148
negative regulation of cytoplasmic transport GO:1903650 2 0.142
Mouse
negative regulation of protein localization to nucleus GO:1900181 2 0.133
Mouse
regulation of cellular metabolic process GO:0031323 320 0.133
cell surface receptor signaling pathway GO:0007166 325 0.126
Zebrafish
regulation of protein targeting GO:1903533 2 0.126
Mouse
protein import GO:0017038 3 0.124
Mouse
response to drug GO:0042493 3 0.119
Rat
immune system development GO:0002520 191 0.119
Mouse
neuron differentiation GO:0030182 353 0.117
Zebrafish
hemopoiesis GO:0030097 183 0.110
Mouse
regulation of gene expression GO:0010468 265 0.107
single organism nuclear import GO:1902593 3 0.104
Mouse
gene expression GO:0010467 252 0.102
regulation of nitrogen compound metabolic process GO:0051171 251 0.100
signal transduction GO:0007165 455 0.096
establishment of localization GO:0051234 244 0.091
Mouse
lipid storage GO:0019915 1 0.091
negative regulation of protein transport GO:0051224 3 0.090
Mouse
organic cyclic compound metabolic process GO:1901360 301 0.089
nucleobase containing compound metabolic process GO:0006139 274 0.088
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.087
embryonic organ development GO:0048568 381 0.085
Rat
specification of symmetry GO:0009799 204 0.083
Zebrafish
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.082
Mouse
nuclear import GO:0051170 3 0.081
Mouse
regulation of circadian rhythm GO:0042752 4 0.081
cellular component movement GO:0006928 335 0.080
regulation of protein localization to nucleus GO:1900180 2 0.079
Mouse
cellular macromolecule metabolic process GO:0044260 391 0.079
response to chemical GO:0042221 320 0.077
regulation of intracellular protein transport GO:0033157 3 0.077
Mouse
autophagy GO:0006914 4 0.076
chordate embryonic development GO:0043009 271 0.076
Zebrafish
hepaticobiliary system development GO:0061008 98 0.075
Zebrafish Rat
heterocycle metabolic process GO:0046483 290 0.074
camera type eye development GO:0043010 222 0.073
Zebrafish
negative regulation of cellular process GO:0048523 283 0.072
mitochondrion organization GO:0007005 4 0.071
small molecule metabolic process GO:0044281 77 0.068
eye morphogenesis GO:0048592 144 0.068
Zebrafish
protein import into nucleus GO:0006606 3 0.067
Mouse
aging GO:0007568 2 0.067
brain development GO:0007420 293 0.067
Zebrafish Rat
sensory organ morphogenesis GO:0090596 200 0.066
Zebrafish
negative regulation of protein import into nucleus GO:0042308 2 0.066
Mouse
regulation of rna metabolic process GO:0051252 224 0.066
glucose import GO:0046323 2 0.066
negative regulation of protein complex assembly GO:0031333 1 0.066
Human
negative regulation of signal transduction GO:0009968 94 0.066
Zebrafish
negative regulation of biological process GO:0048519 304 0.065
regulation of cytoplasmic transport GO:1903649 4 0.064
Mouse
skeletal system development GO:0001501 181 0.061
Mouse
regulation of multicellular organismal process GO:0051239 277 0.061
Mouse
transcription dna templated GO:0006351 181 0.061
rhythmic process GO:0048511 21 0.060
Zebrafish
negative regulation of response to stimulus GO:0048585 104 0.060
Zebrafish
photoreceptor cell differentiation GO:0046530 55 0.059
Zebrafish
negative regulation of cell communication GO:0010648 96 0.058
Zebrafish
cellular protein catabolic process GO:0044257 4 0.058
hindbrain development GO:0030902 91 0.057
Zebrafish
central nervous system development GO:0007417 387 0.057
Zebrafish Rat
heterocycle biosynthetic process GO:0018130 215 0.057
response to monosaccharide GO:0034284 3 0.057
regulation of protein catabolic process GO:0042176 1 0.056
response to stress GO:0006950 263 0.055
Mouse
blood vessel development GO:0001568 246 0.055
guanosine containing compound metabolic process GO:1901068 4 0.055
nucleic acid templated transcription GO:0097659 181 0.055
cellular aromatic compound metabolic process GO:0006725 295 0.054
retina morphogenesis in camera type eye GO:0060042 79 0.054
Zebrafish
regulation of signaling GO:0023051 235 0.054
Zebrafish Mouse
camera type eye morphogenesis GO:0048593 108 0.053
Zebrafish
vasculature development GO:0001944 278 0.053
regulation of protein import into nucleus GO:0042306 2 0.052
Mouse
negative regulation of intracellular transport GO:0032387 3 0.052
Mouse
cellular carbohydrate metabolic process GO:0044262 4 0.051
organic substance biosynthetic process GO:1901576 289 0.051
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.051
liver development GO:0001889 96 0.050
Zebrafish Rat
negative regulation of signaling GO:0023057 96 0.050
Zebrafish
cellular nitrogen compound biosynthetic process GO:0044271 218 0.050
response to hormone GO:0009725 48 0.048
phagocytosis GO:0006909 3 0.047
cellular response to external stimulus GO:0071496 2 0.047
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.047
negative regulation of intracellular protein transport GO:0090317 3 0.046
Mouse
regulation of hormone secretion GO:0046883 2 0.046
negative regulation of macromolecule metabolic process GO:0010605 76 0.045
regulation of glucose import GO:0046324 1 0.045
regulation of establishment of protein localization GO:0070201 4 0.045
Mouse
rna biosynthetic process GO:0032774 181 0.045
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.045
Zebrafish
regulation of metabolic process GO:0019222 359 0.045
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.045
hormone transport GO:0009914 2 0.045
cellular response to nutrient levels GO:0031669 2 0.044
single organism metabolic process GO:0044710 217 0.044
Mouse
nitric oxide biosynthetic process GO:0006809 2 0.044
locomotion GO:0040011 313 0.044
biosynthetic process GO:0009058 294 0.043
regulation of autophagy GO:0010506 3 0.042
gtp metabolic process GO:0046039 4 0.042
regulation of cellular biosynthetic process GO:0031326 245 0.041
determination of heart left right asymmetry GO:0061371 117 0.040
Zebrafish
nucleic acid metabolic process GO:0090304 244 0.040
negative regulation of metabolic process GO:0009892 86 0.040
positive regulation of cell cycle GO:0045787 3 0.039
regulation of developmental process GO:0050793 247 0.039
Mouse
phosphorus metabolic process GO:0006793 109 0.039
transport GO:0006810 220 0.039
Mouse
embryo development ending in birth or egg hatching GO:0009792 271 0.039
Zebrafish
regulation of endocrine process GO:0044060 2 0.038
developmental programmed cell death GO:0010623 4 0.038
aromatic compound biosynthetic process GO:0019438 217 0.038
hormone secretion GO:0046879 2 0.038
regulation of glucose transport GO:0010827 1 0.038
regulation of macromolecule metabolic process GO:0060255 317 0.038
negative regulation of cellular metabolic process GO:0031324 77 0.038
blood circulation GO:0008015 87 0.038
Mouse
digestive tract development GO:0048565 265 0.037
Zebrafish Rat
regulation of reactive oxygen species metabolic process GO:2000377 2 0.037
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.037
negative regulation of catabolic process GO:0009895 3 0.037
endocrine system development GO:0035270 65 0.037
Mouse Rat
regulation of transcription dna templated GO:0006355 213 0.036
regulation of cell communication GO:0010646 232 0.036
Zebrafish Mouse
cell migration GO:0016477 237 0.036
heart development GO:0007507 313 0.036
Zebrafish
mesenchyme development GO:0060485 127 0.036
Zebrafish
cellular response to starvation GO:0009267 1 0.036
modification dependent macromolecule catabolic process GO:0043632 3 0.036
response to organic substance GO:0010033 153 0.036
cellular response to extracellular stimulus GO:0031668 2 0.036
cellular nitrogen compound metabolic process GO:0034641 290 0.036
positive regulation of jun kinase activity GO:0043507 2 0.035
cellular component morphogenesis GO:0032989 336 0.035
immune system process GO:0002376 241 0.035
Mouse
proteasomal protein catabolic process GO:0010498 2 0.035
cell part morphogenesis GO:0032990 246 0.035
protein complex localization GO:0031503 1 0.035
positive regulation of biological process GO:0048518 253 0.035
retina development in camera type eye GO:0060041 146 0.035
Zebrafish
regulation of multicellular organism growth GO:0040014 4 0.035
positive regulation of catabolic process GO:0009896 4 0.034
thyroid gland development GO:0030878 12 0.034
Mouse
carboxylic acid metabolic process GO:0019752 22 0.034
cell motility GO:0048870 244 0.033
regulation of nucleoside metabolic process GO:0009118 2 0.033
epithelial tube morphogenesis GO:0060562 148 0.033
localization of cell GO:0051674 244 0.033
meiotic nuclear division GO:0007126 4 0.033
blood vessel morphogenesis GO:0048514 216 0.033
mesoderm development GO:0007498 88 0.032
Zebrafish
transcription from rna polymerase ii promoter GO:0006366 80 0.032
determination of bilateral symmetry GO:0009855 204 0.032
Zebrafish
nitrogen compound metabolic process GO:0006807 319 0.032
pancreas development GO:0031016 84 0.032
Zebrafish
organic cyclic compound biosynthetic process GO:1901362 223 0.032
camera type eye photoreceptor cell differentiation GO:0060219 19 0.032
Zebrafish
meiotic cell cycle process GO:1903046 3 0.032
negative regulation of protein phosphorylation GO:0001933 4 0.032
cell projection morphogenesis GO:0048858 244 0.032
intracellular transport GO:0046907 32 0.032
Mouse
response to vitamin GO:0033273 3 0.032
cellular response to chemical stimulus GO:0070887 157 0.031
Human Mouse
sensory organ development GO:0007423 393 0.031
Zebrafish
negative regulation of secretion GO:0051048 2 0.031
endocrine process GO:0050886 2 0.031
membrane lipid biosynthetic process GO:0046467 2 0.031
forebrain development GO:0030900 96 0.031
multicellular organism growth GO:0035264 4 0.031
enzyme linked receptor protein signaling pathway GO:0007167 106 0.031
Zebrafish
organelle organization GO:0006996 227 0.031
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.031
nucleobase containing compound biosynthetic process GO:0034654 205 0.030
adrenal gland development GO:0030325 10 0.030
Rat
myeloid cell differentiation GO:0030099 86 0.030
Mouse
response to external stimulus GO:0009605 264 0.030
Rat
regulation of nucleocytoplasmic transport GO:0046822 2 0.030
Mouse
response to nutrient GO:0007584 3 0.030
positive regulation of transport GO:0051050 2 0.030
positive regulation of cellular catabolic process GO:0031331 3 0.029
steroid hormone secretion GO:0035929 1 0.029
cellular response to dna damage stimulus GO:0006974 24 0.029
reactive nitrogen species metabolic process GO:2001057 0 0.029
glial cell proliferation GO:0014009 4 0.029
cellular macromolecule biosynthetic process GO:0034645 224 0.029
regulation of organ growth GO:0046620 3 0.029
modification dependent protein catabolic process GO:0019941 3 0.029
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.029
microtubule organizing center organization GO:0031023 1 0.029
extrinsic apoptotic signaling pathway GO:0097191 3 0.028
single organism membrane fusion GO:0044801 2 0.028
gtp catabolic process GO:0006184 2 0.028
regulation of rna biosynthetic process GO:2001141 213 0.028
morphogenesis of an epithelium GO:0002009 333 0.028
regulation of localization GO:0032879 104 0.028
Mouse
neuron development GO:0048666 262 0.028
Zebrafish
meiosis i GO:0007127 1 0.028
cell morphogenesis GO:0000902 289 0.028
lipid catabolic process GO:0016042 4 0.027
Mouse
regulation of nucleotide catabolic process GO:0030811 2 0.027
guanosine containing compound catabolic process GO:1901069 2 0.027
response to hexose GO:0009746 3 0.027
amine metabolic process GO:0009308 2 0.027
heart process GO:0003015 71 0.027
Mouse
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.027
odontogenesis of dentin containing tooth GO:0042475 1 0.027
reactive oxygen species biosynthetic process GO:1903409 1 0.027
response to glucose GO:0009749 3 0.027
locomotor rhythm GO:0045475 3 0.026
female sex differentiation GO:0046660 4 0.026
positive regulation of neuron apoptotic process GO:0043525 1 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.026
regulation of reproductive process GO:2000241 4 0.026
negative regulation of secretion by cell GO:1903531 2 0.026
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.026
regulation of purine nucleotide catabolic process GO:0033121 2 0.026
sprouting angiogenesis GO:0002040 53 0.026
positive regulation of cytokine production GO:0001819 2 0.026
larval development GO:0002164 2 0.026
tube morphogenesis GO:0035239 349 0.026
rna metabolic process GO:0016070 219 0.026
cell projection organization GO:0030030 284 0.026
circadian sleep wake cycle sleep GO:0050802 1 0.025
establishment of localization in cell GO:0051649 77 0.025
Mouse
cilium organization GO:0044782 71 0.025
carbohydrate homeostasis GO:0033500 1 0.025
positive regulation of rna biosynthetic process GO:1902680 57 0.025
response to ketone GO:1901654 1 0.025
alpha amino acid metabolic process GO:1901605 3 0.025
regulation of cell death GO:0010941 103 0.025
Mouse
cellular amine metabolic process GO:0044106 2 0.025
response to oxygen containing compound GO:1901700 55 0.025
Zebrafish
peptide transport GO:0015833 1 0.025
determination of left right symmetry GO:0007368 179 0.025
Zebrafish
establishment of synaptic vesicle localization GO:0097480 1 0.025
ubiquitin dependent protein catabolic process GO:0006511 3 0.024
embryonic organ morphogenesis GO:0048562 274 0.024
viral process GO:0016032 1 0.024
regulation of gtp catabolic process GO:0033124 2 0.024
positive regulation of map kinase activity GO:0043406 3 0.024
regulation of apoptotic process GO:0042981 98 0.024
Mouse
regulation of cellular protein catabolic process GO:1903362 1 0.024
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.024
intracellular receptor signaling pathway GO:0030522 30 0.024
cartilage development GO:0051216 96 0.024
Mouse
cellular localization GO:0051641 97 0.023
Mouse
macromolecule biosynthetic process GO:0009059 227 0.023
regulation of response to nutrient levels GO:0032107 1 0.023
response to carbohydrate GO:0009743 3 0.023
positive regulation of macromolecule metabolic process GO:0010604 93 0.023
regulation of dna replication GO:0006275 3 0.023
regulation of cell cycle GO:0051726 52 0.023
organic acid metabolic process GO:0006082 31 0.023
macroautophagy GO:0016236 1 0.023
regulation of protein complex assembly GO:0043254 3 0.023
Human
multi organism cellular process GO:0044764 2 0.023
regulation of nervous system development GO:0051960 90 0.023
centrosome organization GO:0051297 1 0.023
leukocyte proliferation GO:0070661 1 0.023
neurological system process GO:0050877 62 0.022
Mouse
negative regulation of kinase activity GO:0033673 4 0.022
oxoacid metabolic process GO:0043436 31 0.022
apoptotic process involved in development GO:1902742 2 0.022
regulation of mitochondrion organization GO:0010821 1 0.022
transmission of nerve impulse GO:0019226 19 0.022
urogenital system development GO:0001655 97 0.022
Rat
neurotransmitter secretion GO:0007269 2 0.022
digestive system development GO:0055123 289 0.022
Zebrafish Rat
response to hydrogen peroxide GO:0042542 3 0.022
positive regulation of cellular component biogenesis GO:0044089 3 0.022
response to corticosteroid GO:0031960 1 0.022
membrane fusion GO:0061025 2 0.022
positive regulation of nucleic acid templated transcription GO:1903508 57 0.022
circadian rhythm GO:0007623 19 0.021
Zebrafish
negative regulation of ras protein signal transduction GO:0046580 1 0.021
zymogen activation GO:0031638 3 0.021
system process GO:0003008 185 0.021
Mouse
positive regulation of neuron death GO:1901216 1 0.021
signal transduction in absence of ligand GO:0038034 1 0.021
skeletal system morphogenesis GO:0048705 102 0.021
Mouse
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.021
regulation of multicellular organismal development GO:2000026 223 0.021
cellular biosynthetic process GO:0044249 286 0.021
erythrocyte differentiation GO:0030218 54 0.021
Mouse
negative regulation of nuclear division GO:0051784 3 0.021
skeletal muscle tissue development GO:0007519 67 0.021
positive regulation of gene expression GO:0010628 71 0.021
ovulation cycle process GO:0022602 2 0.021
stem cell proliferation GO:0072089 4 0.021
positive regulation of muscle tissue development GO:1901863 1 0.021
regulation of cell differentiation GO:0045595 142 0.020
Mouse
angiogenesis GO:0001525 158 0.020
somite development GO:0061053 96 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.020
regulation of protein ubiquitination GO:0031396 3 0.020
regulation of cell activation GO:0050865 1 0.020
development of primary female sexual characteristics GO:0046545 4 0.020
lipid metabolic process GO:0006629 52 0.020
Mouse
regulation of transmembrane transporter activity GO:0022898 2 0.020
regulation of protein binding GO:0043393 3 0.020
regulation of response to oxidative stress GO:1902882 2 0.020
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.020
Rat
regulation of epithelial cell proliferation GO:0050678 3 0.020
negative regulation of cellular catabolic process GO:0031330 3 0.019
striated muscle cell differentiation GO:0051146 129 0.019
Mouse
entrainment of circadian clock GO:0009649 2 0.019
cellular amino acid metabolic process GO:0006520 7 0.019
regulation of carbohydrate metabolic process GO:0006109 4 0.019
response to alkaloid GO:0043279 2 0.019
cell death GO:0008219 121 0.019
Mouse
negative regulation of rna metabolic process GO:0051253 48 0.019
regulation of intracellular signal transduction GO:1902531 57 0.019
regulation of cytokine production GO:0001817 3 0.019
striated muscle cell development GO:0055002 108 0.019
circadian sleep wake cycle process GO:0022410 2 0.019
response to uv GO:0009411 3 0.019
protein metabolic process GO:0019538 183 0.019
appendage development GO:0048736 80 0.019
Zebrafish
regulation of biosynthetic process GO:0009889 250 0.019
developmental growth GO:0048589 166 0.019
multicellular organismal response to stress GO:0033555 2 0.019
regulation of response to extracellular stimulus GO:0032104 1 0.019
apoptotic process GO:0006915 116 0.019
Mouse
negative regulation of biosynthetic process GO:0009890 55 0.019
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.018
interspecies interaction between organisms GO:0044419 4 0.018
regulation of gtpase activity GO:0043087 2 0.018
negative regulation of cellular biosynthetic process GO:0031327 55 0.018
eye development GO:0001654 277 0.018
Zebrafish
hematopoietic or lymphoid organ development GO:0048534 191 0.018
Mouse
response to xenobiotic stimulus GO:0009410 45 0.018
positive regulation of cellular metabolic process GO:0031325 94 0.018
positive regulation of developmental process GO:0051094 50 0.018
Mouse
cell cycle g1 s phase transition GO:0044843 1 0.018
positive regulation of striated muscle tissue development GO:0045844 1 0.018
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.018
female gonad development GO:0008585 4 0.018
regulation of binding GO:0051098 3 0.018
single organism organelle organization GO:1902589 199 0.017
dna templated transcription initiation GO:0006352 1 0.017
Human
organic substance transport GO:0071702 58 0.017
Mouse
tissue remodeling GO:0048771 4 0.017
internal peptidyl lysine acetylation GO:0018393 2 0.017
regulation of postsynaptic membrane potential GO:0060078 1 0.017
regulation of neurogenesis GO:0050767 87 0.017
regulation of receptor activity GO:0010469 2 0.017
organelle fusion GO:0048284 3 0.017
mononuclear cell proliferation GO:0032943 1 0.017
regulation of myotube differentiation GO:0010830 2 0.017
Mouse
single organism localization GO:1902578 225 0.017
Mouse
secondary metabolic process GO:0019748 3 0.017
regulation of nucleic acid templated transcription GO:1903506 213 0.017
positive regulation of apoptotic signaling pathway GO:2001235 1 0.017
spermatid differentiation GO:0048515 2 0.017
circadian sleep wake cycle GO:0042745 2 0.017
response to inorganic substance GO:0010035 38 0.017
positive regulation of immune effector process GO:0002699 3 0.017
positive regulation of cellular process GO:0048522 201 0.017
ovarian follicle development GO:0001541 2 0.017
regulation of mitotic cell cycle GO:0007346 25 0.017
protein polyubiquitination GO:0000209 4 0.017
meiotic chromosome segregation GO:0045132 3 0.017
striated muscle tissue development GO:0014706 110 0.017
regulation of metal ion transport GO:0010959 4 0.017
activation of mapk activity GO:0000187 3 0.017
negative regulation of autophagy GO:0010507 1 0.017
regulation of cell matrix adhesion GO:0001952 1 0.017
response to cold GO:0009409 4 0.017
Mouse
lateral line system development GO:0048925 76 0.016
response to glucocorticoid GO:0051384 1 0.016
cell type specific apoptotic process GO:0097285 22 0.016
Mouse
dna biosynthetic process GO:0071897 3 0.016
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.016
regulation of macromolecule biosynthetic process GO:0010556 225 0.016
cellular response to biotic stimulus GO:0071216 3 0.016
common bile duct development GO:0061009 13 0.016
Zebrafish
regulation of dendrite morphogenesis GO:0048814 3 0.016
b cell activation GO:0042113 2 0.016
macromolecule localization GO:0033036 54 0.016
Mouse
eye photoreceptor cell differentiation GO:0001754 45 0.016
Zebrafish
carbohydrate transport GO:0008643 13 0.016
spermatid development GO:0007286 2 0.016
cilium morphogenesis GO:0060271 85 0.016
growth GO:0040007 174 0.016
cell proliferation GO:0008283 80 0.016
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 8 0.016
erk1 and erk2 cascade GO:0070371 4 0.016
death GO:0016265 121 0.016
Mouse
positive regulation of muscle organ development GO:0048636 1 0.016
cell aging GO:0007569 2 0.016
regulation of blood vessel size GO:0050880 2 0.016
negative regulation of protein kinase activity GO:0006469 4 0.016
regulation of stem cell proliferation GO:0072091 2 0.015
lymphocyte proliferation GO:0046651 1 0.015
hypothalamus cell differentiation GO:0021979 4 0.015
regionalization GO:0003002 274 0.015
cell matrix adhesion GO:0007160 4 0.015
organic substance catabolic process GO:1901575 28 0.015
Mouse
negative regulation of mapk cascade GO:0043409 4 0.015
spindle assembly GO:0051225 2 0.015
cellular response to stress GO:0033554 62 0.015
regulation of protein transport GO:0051223 3 0.015
Mouse
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 2 0.015
muscle structure development GO:0061061 196 0.015
Mouse
phosphorylation GO:0016310 69 0.015
somitogenesis GO:0001756 87 0.015
glucose homeostasis GO:0042593 1 0.015
programmed cell death GO:0012501 119 0.015
Mouse
cellular response to oxygen levels GO:0071453 1 0.015
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.015
interaction with host GO:0051701 4 0.015
lipid homeostasis GO:0055088 3 0.015
membrane invagination GO:0010324 1 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
cellular response to organic substance GO:0071310 105 0.015
Human Mouse
i kappab kinase nf kappab signaling GO:0007249 4 0.015
protein modification process GO:0036211 100 0.015
negative regulation of dna metabolic process GO:0051053 4 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.015
neuroblast proliferation GO:0007405 2 0.015
segmentation GO:0035282 97 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.015
Zebrafish
heart contraction GO:0060047 71 0.015
Mouse
mitochondrial transport GO:0006839 2 0.015
negative regulation of rna biosynthetic process GO:1902679 45 0.015
nitric oxide metabolic process GO:0046209 2 0.015
protein kinase b signaling GO:0043491 9 0.015
positive regulation of stress activated mapk cascade GO:0032874 3 0.015
cellular response to hypoxia GO:0071456 1 0.014
negative regulation of programmed cell death GO:0043069 58 0.014
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.014
regulation of organelle assembly GO:1902115 4 0.014
phagocytosis engulfment GO:0006911 1 0.014
regulation of heart growth GO:0060420 2 0.014
regulation of response to stimulus GO:0048583 269 0.014
Zebrafish Mouse
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.014
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.014
germ line stem cell maintenance GO:0030718 2 0.014
regulation of photoreceptor cell differentiation GO:0046532 2 0.014
cellular response to endogenous stimulus GO:0071495 68 0.014
Human Mouse
single organism cellular localization GO:1902580 46 0.014
Mouse
neuron projection morphogenesis GO:0048812 161 0.014
regulation of response to cytokine stimulus GO:0060759 3 0.014
regulation of chronic inflammatory response GO:0002676 1 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
cellular response to hormone stimulus GO:0032870 39 0.014
Human Mouse
regulation of cellular component movement GO:0051270 55 0.014
cellular protein metabolic process GO:0044267 129 0.014
adult behavior GO:0030534 2 0.014
negative regulation of mitosis GO:0045839 3 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.014
organonitrogen compound metabolic process GO:1901564 74 0.014
regulation of transport GO:0051049 45 0.014
Mouse
regulation of cysteine type endopeptidase activity GO:2000116 21 0.014
organelle assembly GO:0070925 110 0.014
regulation of cytokine mediated signaling pathway GO:0001959 3 0.014
single organism intracellular transport GO:1902582 25 0.014
Mouse
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.014
stem cell division GO:0017145 1 0.014
positive regulation of gtpase activity GO:0043547 1 0.014
regulation of erk1 and erk2 cascade GO:0070372 4 0.013
positive regulation of nucleoside metabolic process GO:0045979 1 0.013
kidney development GO:0001822 92 0.013
Rat
protein secretion GO:0009306 1 0.013
positive regulation of secretion GO:0051047 1 0.013
endosomal transport GO:0016197 2 0.013
positive regulation of translation GO:0045727 1 0.013
reciprocal dna recombination GO:0035825 1 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.013
pyruvate metabolic process GO:0006090 1 0.013
response to topologically incorrect protein GO:0035966 2 0.013
carbohydrate biosynthetic process GO:0016051 1 0.013
heart morphogenesis GO:0003007 156 0.013
regulation of synapse organization GO:0050807 3 0.013
regulation of programmed cell death GO:0043067 101 0.013
Mouse

thraa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.178
Human
nervous system disease DOID:863 0 0.034
cancer DOID:162 0 0.024
disease of cellular proliferation DOID:14566 0 0.024
organ system cancer DOID:0050686 0 0.024
disease of metabolism DOID:0014667 0 0.023
inherited metabolic disorder DOID:655 0 0.018