Danio rerio

0 known processes

thrab

thyroid hormone receptor alpha b

thrab biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to external stimulus GO:0009605 264 0.375
Rat
cellular macromolecule biosynthetic process GO:0034645 224 0.326
Human Zebrafish Mouse Rat
intracellular receptor signaling pathway GO:0030522 30 0.303
Human Zebrafish Mouse
central nervous system development GO:0007417 387 0.250
Zebrafish Rat
transcription dna templated GO:0006351 181 0.183
Human Zebrafish Mouse Rat
regulation of nitrogen compound metabolic process GO:0051171 251 0.169
Human Zebrafish Mouse Rat
heterocycle biosynthetic process GO:0018130 215 0.169
Human Zebrafish Mouse Rat
striated muscle cell differentiation GO:0051146 129 0.167
Mouse
brain development GO:0007420 293 0.148
Zebrafish Rat
gene expression GO:0010467 252 0.147
Human Zebrafish Mouse Rat
single organism localization GO:1902578 225 0.131
Mouse
response to hormone GO:0009725 48 0.131
Human Zebrafish Mouse
determination of left right symmetry GO:0007368 179 0.129
Zebrafish
nucleic acid metabolic process GO:0090304 244 0.119
Human Zebrafish Mouse Rat
negative regulation of protein transport GO:0051224 3 0.117
Mouse
regulation of gene expression GO:0010468 265 0.117
Human Zebrafish Mouse Rat
heart development GO:0007507 313 0.113
Zebrafish
regulation of signal transduction GO:0009966 225 0.113
Zebrafish Mouse
response to drug GO:0042493 3 0.112
Rat
organic substance biosynthetic process GO:1901576 289 0.112
Human Zebrafish Mouse Rat
response to nutrient GO:0007584 3 0.111
response to stress GO:0006950 263 0.110
Mouse
lipid homeostasis GO:0055088 3 0.109
protein localization to nucleus GO:0034504 3 0.109
Mouse
aging GO:0007568 2 0.106
regulation of cytoplasmic transport GO:1903649 4 0.105
Mouse
lipid catabolic process GO:0016042 4 0.105
Mouse
regulation of rna biosynthetic process GO:2001141 213 0.104
Human Zebrafish Mouse Rat
acylglycerol homeostasis GO:0055090 2 0.104
specification of symmetry GO:0009799 204 0.102
Zebrafish
regulation of establishment of protein localization GO:0070201 4 0.101
Mouse
small molecule metabolic process GO:0044281 77 0.098
rna biosynthetic process GO:0032774 181 0.098
Human Zebrafish Mouse Rat
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.096
Human Zebrafish Mouse Rat
regulation of nucleic acid templated transcription GO:1903506 213 0.095
Human Zebrafish Mouse Rat
larval development GO:0002164 2 0.095
locomotion GO:0040011 313 0.092
triglyceride homeostasis GO:0070328 2 0.090
system process GO:0003008 185 0.090
Mouse
sensory organ development GO:0007423 393 0.089
Zebrafish
nuclear import GO:0051170 3 0.089
Mouse
skeletal system development GO:0001501 181 0.088
Mouse
regulation of intracellular protein transport GO:0033157 3 0.088
Mouse
regulation of epithelial cell proliferation GO:0050678 3 0.088
muscle cell differentiation GO:0042692 139 0.086
Mouse
negative regulation of cellular process GO:0048523 283 0.086
Human Zebrafish Mouse
regulation of developmental process GO:0050793 247 0.086
Mouse
response to chemical GO:0042221 320 0.085
Human Zebrafish Mouse Rat
maintenance of location GO:0051235 4 0.084
Mouse
death GO:0016265 121 0.084
Mouse
positive regulation of transport GO:0051050 2 0.084
head development GO:0060322 303 0.081
Zebrafish Rat
transport GO:0006810 220 0.080
Mouse
organic cyclic compound metabolic process GO:1901360 301 0.080
Human Zebrafish Mouse Rat
determination of bilateral symmetry GO:0009855 204 0.080
Zebrafish
embryo development ending in birth or egg hatching GO:0009792 271 0.079
Zebrafish
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.078
Human Zebrafish Mouse Rat
mitochondrion organization GO:0007005 4 0.078
response to vitamin GO:0033273 3 0.078
macromolecule biosynthetic process GO:0009059 227 0.077
Human Zebrafish Mouse Rat
single organism transport GO:0044765 206 0.077
Mouse
hindbrain development GO:0030902 91 0.077
Zebrafish
rna metabolic process GO:0016070 219 0.076
Human Zebrafish Mouse Rat
lipid storage GO:0019915 1 0.076
cellular aromatic compound metabolic process GO:0006725 295 0.076
Human Zebrafish Mouse Rat
steroid hormone mediated signaling pathway GO:0043401 9 0.075
hormone mediated signaling pathway GO:0009755 9 0.075
Human Mouse
positive regulation of biological process GO:0048518 253 0.074
Zebrafish Mouse Rat
epithelial cell differentiation GO:0030855 116 0.073
Mouse
regulation of protein targeting GO:1903533 2 0.072
Mouse
signal transduction GO:0007165 455 0.070
Human Zebrafish Mouse
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.069
Rat
regulation of cellular metabolic process GO:0031323 320 0.068
Human Zebrafish Mouse Rat
protein targeting to nucleus GO:0044744 3 0.068
Mouse
oxoacid metabolic process GO:0043436 31 0.068
regulation of primary metabolic process GO:0080090 311 0.067
Human Zebrafish Mouse Rat
generation of neurons GO:0048699 385 0.067
Zebrafish
neuron differentiation GO:0030182 353 0.067
Zebrafish
response to organic substance GO:0010033 153 0.066
Human Zebrafish Mouse
gland development GO:0048732 143 0.065
Zebrafish Mouse Rat
aromatic compound biosynthetic process GO:0019438 217 0.063
Human Zebrafish Mouse Rat
establishment of localization in cell GO:0051649 77 0.061
Mouse
circulatory system process GO:0003013 87 0.060
Mouse
cellular response to external stimulus GO:0071496 2 0.060
organic cyclic compound biosynthetic process GO:1901362 223 0.060
Human Zebrafish Mouse Rat
phagocytosis GO:0006909 3 0.059
lipid metabolic process GO:0006629 52 0.059
Mouse
striated muscle cell development GO:0055002 108 0.058
negative regulation of cell death GO:0060548 60 0.058
negative regulation of cytoplasmic transport GO:1903650 2 0.058
Mouse
nucleocytoplasmic transport GO:0006913 4 0.058
Mouse
tube morphogenesis GO:0035239 349 0.055
cognition GO:0050890 1 0.055
Mouse
organic acid metabolic process GO:0006082 31 0.055
cellular component movement GO:0006928 335 0.055
cell morphogenesis GO:0000902 289 0.054
regulation of multicellular organismal process GO:0051239 277 0.054
Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.052
Human Zebrafish Mouse Rat
cellular biosynthetic process GO:0044249 286 0.051
Human Zebrafish Mouse Rat
response to glucose GO:0009749 3 0.051
programmed cell death GO:0012501 119 0.051
Mouse
cellular macromolecule metabolic process GO:0044260 391 0.051
Human Zebrafish Mouse Rat
heterocycle metabolic process GO:0046483 290 0.050
Human Zebrafish Mouse Rat
cellular nitrogen compound biosynthetic process GO:0044271 218 0.050
Human Zebrafish Mouse Rat
cell projection morphogenesis GO:0048858 244 0.050
nucleobase containing compound biosynthetic process GO:0034654 205 0.049
Human Zebrafish Mouse Rat
protein import GO:0017038 3 0.049
Mouse
regulation of tube size GO:0035150 2 0.049
negative regulation of protein localization to nucleus GO:1900181 2 0.048
Mouse
regulation of cell differentiation GO:0045595 142 0.048
Mouse
macromolecule localization GO:0033036 54 0.048
Mouse
positive regulation of rna metabolic process GO:0051254 59 0.048
Zebrafish Mouse Rat
transcription from rna polymerase ii promoter GO:0006366 80 0.048
Human Zebrafish Mouse Rat
regulation of transcription dna templated GO:0006355 213 0.048
Human Zebrafish Mouse Rat
negative regulation of macromolecule metabolic process GO:0010605 76 0.048
Human Zebrafish Mouse
nitrogen compound metabolic process GO:0006807 319 0.048
Human Zebrafish Mouse Rat
nuclear transport GO:0051169 4 0.048
Mouse
positive regulation of biosynthetic process GO:0009891 68 0.047
Zebrafish Mouse Rat
determination of heart left right asymmetry GO:0061371 117 0.047
Zebrafish
response to monosaccharide GO:0034284 3 0.047
nucleobase containing compound metabolic process GO:0006139 274 0.047
Human Zebrafish Mouse Rat
cellular response to chemical stimulus GO:0070887 157 0.047
Human Mouse
regulation of localization GO:0032879 104 0.046
Mouse
regulation of macromolecule biosynthetic process GO:0010556 225 0.046
Human Zebrafish Mouse Rat
carboxylic acid metabolic process GO:0019752 22 0.046
single organism metabolic process GO:0044710 217 0.046
Mouse
regulation of programmed cell death GO:0043067 101 0.045
Mouse
cell substrate adhesion GO:0031589 4 0.043
segmentation GO:0035282 97 0.043
negative regulation of molecular function GO:0044092 23 0.043
Rat
embryonic organ development GO:0048568 381 0.042
Rat
regulation of macromolecule metabolic process GO:0060255 317 0.042
Human Zebrafish Mouse Rat
urogenital system development GO:0001655 97 0.041
Rat
long chain fatty acid metabolic process GO:0001676 1 0.041
establishment of protein localization to organelle GO:0072594 4 0.041
Mouse
establishment of localization GO:0051234 244 0.041
Mouse
kidney development GO:0001822 92 0.040
Rat
ion transport GO:0006811 114 0.040
regulation of nucleocytoplasmic transport GO:0046822 2 0.040
Mouse
regulation of blood vessel size GO:0050880 2 0.040
heart morphogenesis GO:0003007 156 0.039
heart contraction GO:0060047 71 0.039
Mouse
blood circulation GO:0008015 87 0.039
Mouse
positive regulation of nucleic acid templated transcription GO:1903508 57 0.038
Zebrafish Mouse Rat
regulation of blood pressure GO:0008217 1 0.038
regulation of cellular ketone metabolic process GO:0010565 7 0.038
regulation of dna replication GO:0006275 3 0.038
regulation of rna metabolic process GO:0051252 224 0.038
Human Zebrafish Mouse Rat
positive regulation of cell differentiation GO:0045597 30 0.038
Mouse
response to carbohydrate GO:0009743 3 0.038
multi organism process GO:0051704 134 0.038
Mouse
regulation of cell death GO:0010941 103 0.038
Mouse
regulation of apoptotic process GO:0042981 98 0.038
Mouse
muscle cell development GO:0055001 115 0.037
positive regulation of gene expression GO:0010628 71 0.037
Zebrafish Mouse Rat
alcohol biosynthetic process GO:0046165 2 0.037
liver development GO:0001889 96 0.037
Zebrafish Rat
amine metabolic process GO:0009308 2 0.037
regulation of protein localization to nucleus GO:1900180 2 0.036
Mouse
cellular component assembly GO:0022607 170 0.036
Human
skeletal muscle tissue development GO:0007519 67 0.036
immune system process GO:0002376 241 0.036
Mouse
muscle tissue development GO:0060537 110 0.036
regulation of signaling GO:0023051 235 0.036
Zebrafish Mouse
homeostatic process GO:0042592 142 0.035
Mouse
behavior GO:0007610 74 0.035
Mouse
regulation of biosynthetic process GO:0009889 250 0.035
Human Zebrafish Mouse Rat
response to acid chemical GO:0001101 17 0.034
Zebrafish
retina development in camera type eye GO:0060041 146 0.034
Zebrafish
cellular amine metabolic process GO:0044106 2 0.034
regulation of biological quality GO:0065008 263 0.034
Mouse
biosynthetic process GO:0009058 294 0.034
Human Zebrafish Mouse Rat
cellular response to nutrient levels GO:0031669 2 0.034
positive regulation of cellular biosynthetic process GO:0031328 68 0.034
Zebrafish Mouse Rat
response to oxygen containing compound GO:1901700 55 0.034
Zebrafish
cellular component morphogenesis GO:0032989 336 0.034
regulation of binding GO:0051098 3 0.033
cellular component biogenesis GO:0044085 178 0.033
Human
cellular response to extracellular stimulus GO:0031668 2 0.033
positive regulation of cell cycle GO:0045787 3 0.033
fatty acid transport GO:0015908 1 0.033
cellular response to organic substance GO:0071310 105 0.033
Human Mouse
nucleic acid templated transcription GO:0097659 181 0.033
Human Zebrafish Mouse Rat
peptide transport GO:0015833 1 0.033
regulation of cellular biosynthetic process GO:0031326 245 0.033
Human Zebrafish Mouse Rat
digestive tract development GO:0048565 265 0.032
Zebrafish Rat
heart process GO:0003015 71 0.032
Mouse
positive regulation of rna biosynthetic process GO:1902680 57 0.032
Zebrafish Mouse Rat
positive regulation of macromolecule metabolic process GO:0010604 93 0.032
Zebrafish Mouse Rat
response to endogenous stimulus GO:0009719 83 0.032
Human Zebrafish Mouse
immune system development GO:0002520 191 0.032
Mouse
response to ketone GO:1901654 1 0.031
regulation of molecular function GO:0065009 70 0.031
Rat
embryonic organ morphogenesis GO:0048562 274 0.031
cell migration GO:0016477 237 0.031
retinoic acid receptor signaling pathway GO:0048384 16 0.031
Zebrafish
regulation of cytokine production GO:0001817 3 0.031
regulation of multicellular organismal development GO:2000026 223 0.030
negative regulation of transcription dna templated GO:0045892 45 0.030
Human Zebrafish Mouse
smooth muscle contraction GO:0006939 2 0.030
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.030
Zebrafish Mouse Rat
regulation of cell communication GO:0010646 232 0.030
Zebrafish Mouse
hormone secretion GO:0046879 2 0.030
embryonic heart tube development GO:0035050 133 0.030
regulation of hormone secretion GO:0046883 2 0.030
guanosine containing compound metabolic process GO:1901068 4 0.030
response to alkaloid GO:0043279 2 0.030
negative regulation of intracellular protein transport GO:0090317 3 0.029
Mouse
eye development GO:0001654 277 0.029
Zebrafish
negative regulation of metabolic process GO:0009892 86 0.029
Human Zebrafish Mouse
regulation of blood circulation GO:1903522 32 0.029
Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.029
Human Zebrafish Mouse
photoreceptor cell differentiation GO:0046530 55 0.029
Zebrafish
gtp metabolic process GO:0046039 4 0.029
intracellular signal transduction GO:0035556 85 0.029
cellular response to organic cyclic compound GO:0071407 38 0.029
camera type eye development GO:0043010 222 0.029
Zebrafish
neuron development GO:0048666 262 0.029
Zebrafish
regulation of reproductive process GO:2000241 4 0.029
negative regulation of protein complex assembly GO:0031333 1 0.028
Human
regulation of metal ion transport GO:0010959 4 0.028
positive regulation of secretion by cell GO:1903532 1 0.028
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.028
response to retinoic acid GO:0032526 6 0.028
Zebrafish
long chain fatty acid transport GO:0015909 1 0.028
secondary metabolic process GO:0019748 3 0.027
response to hexose GO:0009746 3 0.027
myeloid cell differentiation GO:0030099 86 0.027
Mouse
regulation of protein catabolic process GO:0042176 1 0.027
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.027
Mouse
response to vitamin b3 GO:0033552 2 0.026
hindbrain morphogenesis GO:0021575 22 0.026
Zebrafish
regulation of sequence specific dna binding transcription factor activity GO:0051090 9 0.026
Rat
regulation of cellular amine metabolic process GO:0033238 0 0.026
single organism nuclear import GO:1902593 3 0.026
Mouse
cell motility GO:0048870 244 0.026
protein secretion GO:0009306 1 0.026
reproduction GO:0000003 40 0.026
Mouse
protein modification process GO:0036211 100 0.026
negative regulation of epithelial cell proliferation GO:0050680 1 0.025
chordate embryonic development GO:0043009 271 0.025
Zebrafish
negative regulation of protein kinase activity GO:0006469 4 0.025
positive regulation of secretion GO:0051047 1 0.025
cell death GO:0008219 121 0.025
Mouse
negative regulation of dna metabolic process GO:0051053 4 0.025
negative regulation of dna replication GO:0008156 2 0.025
multicellular organism reproduction GO:0032504 35 0.025
Mouse
dorsal ventral pattern formation GO:0009953 125 0.025
multicellular organism growth GO:0035264 4 0.025
skeletal system morphogenesis GO:0048705 102 0.025
Mouse
meiotic nuclear division GO:0007126 4 0.025
negative regulation of multicellular organismal process GO:0051241 69 0.024
somite development GO:0061053 96 0.024
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.024
positive regulation of cytokine production GO:0001819 2 0.024
regulation of purine nucleotide catabolic process GO:0033121 2 0.024
regulation of meiotic cell cycle GO:0051445 1 0.024
epithelial tube morphogenesis GO:0060562 148 0.024
guanosine containing compound catabolic process GO:1901069 2 0.024
apoptotic process GO:0006915 116 0.024
Mouse
localization of cell GO:0051674 244 0.024
forebrain development GO:0030900 96 0.024
muscle fiber development GO:0048747 52 0.023
response to corticosteroid GO:0031960 1 0.023
morphogenesis of an epithelium GO:0002009 333 0.023
regionalization GO:0003002 274 0.023
adult behavior GO:0030534 2 0.023
cartilage development GO:0051216 96 0.023
Mouse
response to organic cyclic compound GO:0014070 51 0.023
positive regulation of developmental process GO:0051094 50 0.023
Mouse
organelle organization GO:0006996 227 0.023
cellular localization GO:0051641 97 0.022
Mouse
negative regulation of protein phosphorylation GO:0001933 4 0.022
negative regulation of rna metabolic process GO:0051253 48 0.022
Human Zebrafish Mouse
growth GO:0040007 174 0.022
response to inorganic substance GO:0010035 38 0.022
cellular ketone metabolic process GO:0042180 11 0.022
regulation of myotube differentiation GO:0010830 2 0.022
Mouse
response to cold GO:0009409 4 0.022
Mouse
protein import into nucleus GO:0006606 3 0.022
Mouse
negative regulation of intracellular transport GO:0032387 3 0.022
Mouse
heart looping GO:0001947 94 0.022
regulation of cell development GO:0060284 100 0.022
diterpenoid metabolic process GO:0016101 15 0.022
xenobiotic metabolic process GO:0006805 4 0.022
negative regulation of biosynthetic process GO:0009890 55 0.022
Human Zebrafish Mouse
regulation of gtpase activity GO:0043087 2 0.022
stem cell maintenance GO:0019827 4 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
regulation of system process GO:0044057 40 0.021
Mouse
eye photoreceptor cell development GO:0042462 30 0.021
Zebrafish
eye photoreceptor cell differentiation GO:0001754 45 0.021
Zebrafish
meiotic cell cycle process GO:1903046 3 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.021
Zebrafish Mouse Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.021
Zebrafish Mouse Rat
negative regulation of cellular metabolic process GO:0031324 77 0.021
Human Zebrafish Mouse
response to biotic stimulus GO:0009607 97 0.021
protein acetylation GO:0006473 2 0.021
regulation of inflammatory response GO:0050727 2 0.021
regulation of nucleotide catabolic process GO:0030811 2 0.021
modification dependent macromolecule catabolic process GO:0043632 3 0.021
sensory organ morphogenesis GO:0090596 200 0.021
Zebrafish
embryonic heart tube morphogenesis GO:0003143 108 0.021
striated muscle tissue development GO:0014706 110 0.021
negative regulation of cell communication GO:0010648 96 0.021
Zebrafish
developmental maturation GO:0021700 34 0.021
cellular response to lipid GO:0071396 39 0.021
cellular protein catabolic process GO:0044257 4 0.020
negative regulation of cellular biosynthetic process GO:0031327 55 0.020
Human Zebrafish Mouse
fin development GO:0033333 77 0.020
Zebrafish
regulation of production of molecular mediator of immune response GO:0002700 1 0.020
cellular amino acid metabolic process GO:0006520 7 0.020
rna localization GO:0006403 4 0.020
phagocytosis engulfment GO:0006911 1 0.020
g1 s transition of mitotic cell cycle GO:0000082 1 0.020
oxidation reduction process GO:0055114 41 0.020
skeletal muscle organ development GO:0060538 78 0.020
neurological system process GO:0050877 62 0.020
Mouse
digestive system development GO:0055123 289 0.020
Zebrafish Rat
gtp catabolic process GO:0006184 2 0.020
glucose homeostasis GO:0042593 1 0.020
mesenchyme development GO:0060485 127 0.020
Zebrafish
negative regulation of catabolic process GO:0009895 3 0.019
regulation of intracellular signal transduction GO:1902531 57 0.019
positive regulation of cellular component biogenesis GO:0044089 3 0.019
carbohydrate homeostasis GO:0033500 1 0.019
multicellular organismal signaling GO:0035637 22 0.019
cellular response to retinoic acid GO:0071300 1 0.019
chemical homeostasis GO:0048878 49 0.019
lateral line system development GO:0048925 76 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.019
Human Zebrafish Mouse Rat
positive regulation of cellular catabolic process GO:0031331 3 0.019
positive regulation of catabolic process GO:0009896 4 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.018
cell cycle g1 s phase transition GO:0044843 1 0.018
regulation of stem cell proliferation GO:0072091 2 0.018
regulation of carbohydrate metabolic process GO:0006109 4 0.018
regulation of proteolysis GO:0030162 24 0.018
endocrine system development GO:0035270 65 0.018
Mouse Rat
regulation of gtp catabolic process GO:0033124 2 0.018
positive regulation of multicellular organismal process GO:0051240 52 0.018
cellular response to oxygen levels GO:0071453 1 0.018
negative regulation of kinase activity GO:0033673 4 0.018
regulation of calcium ion transport GO:0051924 2 0.018
response to other organism GO:0051707 97 0.018
intrahepatic bile duct development GO:0035622 11 0.018
Zebrafish
stem cell proliferation GO:0072089 4 0.018
ossification GO:0001503 23 0.018
Mouse
lipid oxidation GO:0034440 1 0.018
cell projection organization GO:0030030 284 0.018
negative regulation of secretion GO:0051048 2 0.018
production of molecular mediator of immune response GO:0002440 2 0.018
regulation of protein import into nucleus GO:0042306 2 0.018
Mouse
positive regulation of immune effector process GO:0002699 3 0.017
response to external biotic stimulus GO:0043207 97 0.017
proteasomal protein catabolic process GO:0010498 2 0.017
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.017
fatty acid metabolic process GO:0006631 5 0.017
regulation of protein transport GO:0051223 3 0.017
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.017
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.017
Zebrafish
response to metal ion GO:0010038 34 0.017
cellular response to steroid hormone stimulus GO:0071383 31 0.017
regulation of cell activation GO:0050865 1 0.017
response to steroid hormone GO:0048545 35 0.017
organic substance transport GO:0071702 58 0.017
Mouse
positive regulation of gtpase activity GO:0043547 1 0.017
camera type eye photoreceptor cell differentiation GO:0060219 19 0.017
Zebrafish
muscle organ development GO:0007517 101 0.017
response to glucocorticoid GO:0051384 1 0.017
collagen metabolic process GO:0032963 2 0.016
eye morphogenesis GO:0048592 144 0.016
Zebrafish
embryonic skeletal system development GO:0048706 97 0.016
extrinsic apoptotic signaling pathway GO:0097191 3 0.016
cytokinesis GO:0000910 3 0.016
autophagy GO:0006914 4 0.016
negative regulation of apoptotic process GO:0043066 55 0.016
gastrulation GO:0007369 208 0.016
fatty acid oxidation GO:0019395 1 0.016
i kappab kinase nf kappab signaling GO:0007249 4 0.016
peptidyl lysine acetylation GO:0018394 2 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.016
Human Zebrafish Mouse
muscle structure development GO:0061061 196 0.016
Mouse
response to abiotic stimulus GO:0009628 122 0.016
Mouse
membrane invagination GO:0010324 1 0.016
interspecies interaction between organisms GO:0044419 4 0.016
digestive tract morphogenesis GO:0048546 231 0.016
regulation of protein ubiquitination GO:0031396 3 0.016
cell surface receptor signaling pathway GO:0007166 325 0.016
Zebrafish
multicellular organismal metabolic process GO:0044236 2 0.016
reactive oxygen species biosynthetic process GO:1903409 1 0.016
taxis GO:0042330 109 0.015
connective tissue development GO:0061448 99 0.015
Mouse
hormone transport GO:0009914 2 0.015
antimicrobial humoral response GO:0019730 2 0.015
blood vessel development GO:0001568 246 0.015
positive regulation of stress activated mapk cascade GO:0032874 3 0.015
anterior posterior pattern specification GO:0009952 152 0.015
circadian regulation of gene expression GO:0032922 8 0.015
Zebrafish
negative regulation of rna biosynthetic process GO:1902679 45 0.015
Human Zebrafish Mouse
transmission of nerve impulse GO:0019226 19 0.015
regeneration GO:0031099 91 0.015
defense response to other organism GO:0098542 33 0.015
erk1 and erk2 cascade GO:0070371 4 0.015
modification dependent protein catabolic process GO:0019941 3 0.015
cellular protein modification process GO:0006464 100 0.015
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.015
regulation of rho protein signal transduction GO:0035023 2 0.015
regulation of cellular protein catabolic process GO:1903362 1 0.015
positive regulation of nucleoside metabolic process GO:0045979 1 0.015
multicellular organismal response to stress GO:0033555 2 0.015
ear development GO:0043583 127 0.015
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.015
fertilization GO:0009566 3 0.015
positive regulation of cellular metabolic process GO:0031325 94 0.015
Zebrafish Mouse Rat
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.015
anion transport GO:0006820 38 0.015
negative regulation of defense response GO:0031348 2 0.015
cell matrix adhesion GO:0007160 4 0.015
negative regulation of biological process GO:0048519 304 0.015
Human Zebrafish Mouse Rat
negative regulation of response to stimulus GO:0048585 104 0.015
Zebrafish
regulation of cell shape GO:0008360 1 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.014
protein localization GO:0008104 40 0.014
Mouse
b cell activation GO:0042113 2 0.014
angiogenesis GO:0001525 158 0.014
regulation of cellular component organization GO:0051128 86 0.014
Human
regulation of reactive oxygen species metabolic process GO:2000377 2 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.014
regulation of nucleoside metabolic process GO:0009118 2 0.014
hepaticobiliary system development GO:0061008 98 0.014
Zebrafish Rat
tissue remodeling GO:0048771 4 0.014
cellular response to hormone stimulus GO:0032870 39 0.014
Human Mouse
neuroblast proliferation GO:0007405 2 0.014
response to temperature stimulus GO:0009266 15 0.014
Mouse
defense response GO:0006952 47 0.014
synaptic growth at neuromuscular junction GO:0051124 2 0.014
alpha amino acid metabolic process GO:1901605 3 0.014
ovulation cycle process GO:0022602 2 0.014
regulation of protein binding GO:0043393 3 0.014
somitogenesis GO:0001756 87 0.014
regulation of organ growth GO:0046620 3 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
cation transport GO:0006812 81 0.014
cell part morphogenesis GO:0032990 246 0.014
cellular response to starvation GO:0009267 1 0.014
diencephalon development GO:0021536 58 0.014
negative regulation of protein import into nucleus GO:0042308 2 0.014
Mouse
dna biosynthetic process GO:0071897 3 0.014
ubiquitin dependent protein catabolic process GO:0006511 3 0.014
negative regulation of signal transduction GO:0009968 94 0.014
Zebrafish
action potential GO:0001508 19 0.014
cellular carbohydrate metabolic process GO:0044262 4 0.013
negative regulation of nucleic acid templated transcription GO:1903507 45 0.013
Human Zebrafish Mouse
g2 m transition of mitotic cell cycle GO:0000086 4 0.013
cellular response to stress GO:0033554 62 0.013
lymphocyte proliferation GO:0046651 1 0.013
lateral line development GO:0048882 66 0.013
positive regulation of gtp catabolic process GO:0033126 1 0.013
positive regulation of cell activation GO:0050867 1 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
negative regulation of bmp signaling pathway GO:0030514 13 0.013
Zebrafish
cytoskeleton organization GO:0007010 96 0.013
positive regulation of gliogenesis GO:0014015 2 0.013
regulation of protein complex assembly GO:0043254 3 0.013
Human
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.013
cellular response to endogenous stimulus GO:0071495 68 0.013
Human Mouse
embryonic cranial skeleton morphogenesis GO:0048701 90 0.013
membrane fusion GO:0061025 2 0.013
cytosolic calcium ion transport GO:0060401 3 0.013
vasculature development GO:0001944 278 0.013
phosphatidylinositol mediated signaling GO:0048015 2 0.013
stem cell division GO:0017145 1 0.013
single organism membrane fusion GO:0044801 2 0.013
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
cilium morphogenesis GO:0060271 85 0.013
hemopoiesis GO:0030097 183 0.013
Mouse
cellular protein metabolic process GO:0044267 129 0.013
negative regulation of cellular catabolic process GO:0031330 3 0.012
mitochondrial transport GO:0006839 2 0.012
terpenoid metabolic process GO:0006721 15 0.012
pharyngeal system development GO:0060037 18 0.012
Zebrafish
negative regulation of cytokine production GO:0001818 1 0.012
chemotaxis GO:0006935 104 0.012
single organism organelle organization GO:1902589 199 0.012
regulation of cell substrate adhesion GO:0010810 1 0.012
positive regulation of lipid metabolic process GO:0045834 1 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.012
camera type eye morphogenesis GO:0048593 108 0.012
Zebrafish
energy reserve metabolic process GO:0006112 2 0.012
retinoid metabolic process GO:0001523 15 0.012

thrab disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.089
Human
cancer DOID:162 0 0.020
disease of cellular proliferation DOID:14566 0 0.020
organ system cancer DOID:0050686 0 0.020
disease of metabolism DOID:0014667 0 0.015
inherited metabolic disorder DOID:655 0 0.015