Danio rerio

95 known processes

thrb

thyroid hormone receptor beta

(Aliases: wu:fj24f03,NR1A2,trb,fj24f03,TR-beta,TR[b]1)

thrb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of transcription dna templated GO:0045893 57 0.799
Zebrafish Mouse
regulation of biosynthetic process GO:0009889 250 0.749
regulation of cellular metabolic process GO:0031323 320 0.699
regulation of primary metabolic process GO:0080090 311 0.673
regulation of nucleic acid templated transcription GO:1903506 213 0.655
regulation of cellular biosynthetic process GO:0031326 245 0.634
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.617
regulation of gene expression GO:0010468 265 0.613
neuron differentiation GO:0030182 353 0.610
regulation of transcription dna templated GO:0006355 213 0.595
macromolecule biosynthetic process GO:0009059 227 0.568
organic cyclic compound biosynthetic process GO:1901362 223 0.555
cellular component morphogenesis GO:0032989 336 0.536
nucleobase containing compound metabolic process GO:0006139 274 0.485
gene expression GO:0010467 252 0.482
cellular aromatic compound metabolic process GO:0006725 295 0.461
regulation of multicellular organismal process GO:0051239 277 0.459
Mouse Rat
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.452
organic substance biosynthetic process GO:1901576 289 0.442
muscle structure development GO:0061061 196 0.433
regulation of macromolecule biosynthetic process GO:0010556 225 0.432
generation of neurons GO:0048699 385 0.424
nucleic acid metabolic process GO:0090304 244 0.419
brain development GO:0007420 293 0.409
Zebrafish
rna biosynthetic process GO:0032774 181 0.404
aging GO:0007568 2 0.404
positive regulation of gene expression GO:0010628 71 0.395
Zebrafish Mouse
regulation of developmental process GO:0050793 247 0.394
Rat
digestive tract development GO:0048565 265 0.380
Zebrafish
central nervous system development GO:0007417 387 0.369
Zebrafish
cellular macromolecule biosynthetic process GO:0034645 224 0.365
regionalization GO:0003002 274 0.361
regulation of nitrogen compound metabolic process GO:0051171 251 0.361
cellular biosynthetic process GO:0044249 286 0.360
positive regulation of cellular process GO:0048522 201 0.355
Zebrafish Mouse Rat
neuron development GO:0048666 262 0.349
regulation of macromolecule metabolic process GO:0060255 317 0.340
regulation of rna biosynthetic process GO:2001141 213 0.338
positive regulation of biological process GO:0048518 253 0.319
Zebrafish Mouse Rat
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.300
Zebrafish Mouse
transcription from rna polymerase ii promoter GO:0006366 80 0.300
negative regulation of protein phosphorylation GO:0001933 4 0.294
embryonic organ development GO:0048568 381 0.283
Rat
retina development in camera type eye GO:0060041 146 0.280
positive regulation of cellular biosynthetic process GO:0031328 68 0.271
Zebrafish Mouse
transcription dna templated GO:0006351 181 0.260
negative regulation of gene expression GO:0010629 65 0.258
Zebrafish Mouse
head development GO:0060322 303 0.256
Zebrafish
biosynthetic process GO:0009058 294 0.255
locomotion GO:0040011 313 0.251
nucleobase containing compound biosynthetic process GO:0034654 205 0.246
anterior posterior pattern specification GO:0009952 152 0.244
response to stress GO:0006950 263 0.241
heterocycle metabolic process GO:0046483 290 0.240
nucleic acid templated transcription GO:0097659 181 0.238
skeletal system development GO:0001501 181 0.235
Rat
heart development GO:0007507 313 0.234
Zebrafish
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.219
positive regulation of rna biosynthetic process GO:1902680 57 0.215
Zebrafish Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.214
gastrulation GO:0007369 208 0.213
digestive tract morphogenesis GO:0048546 231 0.212
regulation of metabolic process GO:0019222 359 0.207
chemotaxis GO:0006935 104 0.207
positive regulation of cellular metabolic process GO:0031325 94 0.207
Zebrafish Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.206
Zebrafish Mouse
rna metabolic process GO:0016070 219 0.197
cell morphogenesis GO:0000902 289 0.195
tube morphogenesis GO:0035239 349 0.190
nitrogen compound metabolic process GO:0006807 319 0.188
positive regulation of rna metabolic process GO:0051254 59 0.186
Zebrafish Mouse
system process GO:0003008 185 0.185
Mouse
cellular component movement GO:0006928 335 0.185
cell motility GO:0048870 244 0.183
negative regulation of signal transduction GO:0009968 94 0.179
Zebrafish
negative regulation of biological process GO:0048519 304 0.173
Zebrafish Mouse
multicellular organismal signaling GO:0035637 22 0.170
inner ear development GO:0048839 126 0.169
cellular nitrogen compound metabolic process GO:0034641 290 0.169
negative regulation of nucleic acid templated transcription GO:1903507 45 0.166
Zebrafish Mouse
sensory organ development GO:0007423 393 0.165
cell projection organization GO:0030030 284 0.161
negative regulation of developmental process GO:0051093 65 0.159
protein import into nucleus GO:0006606 3 0.156
positive regulation of nucleic acid templated transcription GO:1903508 57 0.156
Zebrafish Mouse
cognition GO:0050890 1 0.156
aromatic compound biosynthetic process GO:0019438 217 0.154
positive regulation of macromolecule metabolic process GO:0010604 93 0.153
Zebrafish Mouse
positive regulation of biosynthetic process GO:0009891 68 0.150
Zebrafish Mouse
eye development GO:0001654 277 0.149
single organism nuclear import GO:1902593 3 0.146
cellular macromolecule metabolic process GO:0044260 391 0.146
signal transduction GO:0007165 455 0.142
sensory organ morphogenesis GO:0090596 200 0.142
heterocycle biosynthetic process GO:0018130 215 0.141
negative regulation of protein kinase activity GO:0006469 4 0.135
stem cell development GO:0048864 82 0.134
positive regulation of metabolic process GO:0009893 108 0.130
Zebrafish Mouse
response to organic substance GO:0010033 153 0.128
Zebrafish
regulation of cell differentiation GO:0045595 142 0.127
Rat
maintenance of location GO:0051235 4 0.125
establishment of protein localization to organelle GO:0072594 4 0.121
cell adhesion GO:0007155 40 0.121
cell migration GO:0016477 237 0.116
positive regulation of multicellular organismal process GO:0051240 52 0.115
Rat
convergent extension GO:0060026 118 0.114
actin cytoskeleton organization GO:0030036 63 0.114
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.114
Zebrafish Mouse
nucleocytoplasmic transport GO:0006913 4 0.112
larval development GO:0002164 2 0.111
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.109
Zebrafish Mouse
protein localization to nucleus GO:0034504 3 0.107
neuron remodeling GO:0016322 1 0.105
negative regulation of biosynthetic process GO:0009890 55 0.104
Zebrafish Mouse
regulation of stem cell differentiation GO:2000736 4 0.102
response to abiotic stimulus GO:0009628 122 0.101
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.101
determination of left right symmetry GO:0007368 179 0.101
Zebrafish
cell migration involved in gastrulation GO:0042074 79 0.101
multicellular organism growth GO:0035264 4 0.100
behavior GO:0007610 74 0.099
Mouse
response to drug GO:0042493 3 0.099
ameboidal type cell migration GO:0001667 143 0.099
determination of bilateral symmetry GO:0009855 204 0.099
Zebrafish
embryo development ending in birth or egg hatching GO:0009792 271 0.098
Zebrafish
mechanosensory behavior GO:0007638 2 0.097
response to chemical GO:0042221 320 0.096
Zebrafish
chordate embryonic development GO:0043009 271 0.093
Zebrafish
regulation of signal transduction GO:0009966 225 0.093
Zebrafish
photoreceptor cell differentiation GO:0046530 55 0.091
neurological system process GO:0050877 62 0.090
Mouse
intracellular receptor signaling pathway GO:0030522 30 0.090
nuclear import GO:0051170 3 0.088
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.088
transmission of nerve impulse GO:0019226 19 0.088
response to external stimulus GO:0009605 264 0.086
organic cyclic compound metabolic process GO:1901360 301 0.086
heart morphogenesis GO:0003007 156 0.086
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.086
ossification GO:0001503 23 0.085
Rat
regulation of anatomical structure morphogenesis GO:0022603 130 0.083
localization of cell GO:0051674 244 0.083
developmental growth GO:0048589 166 0.081
cellular component assembly GO:0022607 170 0.080
single organism localization GO:1902578 225 0.079
negative regulation of cellular biosynthetic process GO:0031327 55 0.079
Zebrafish Mouse
regulation of nervous system development GO:0051960 90 0.079
ear development GO:0043583 127 0.078
growth GO:0040007 174 0.077
photoreceptor cell fate commitment GO:0046552 1 0.077
autophagy GO:0006914 4 0.077
purine containing compound biosynthetic process GO:0072522 20 0.076
regulation of multicellular organism growth GO:0040014 4 0.076
regulation of cellular amino acid metabolic process GO:0006521 0 0.075
macromolecule modification GO:0043412 111 0.075
neuron projection development GO:0031175 180 0.074
digestive system development GO:0055123 289 0.074
Zebrafish
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.073
regulation of cellular ketone metabolic process GO:0010565 7 0.073
chemosensory behavior GO:0007635 1 0.072
regulation of biological quality GO:0065008 263 0.072
Mouse
cellular component biogenesis GO:0044085 178 0.071
striated muscle tissue development GO:0014706 110 0.069
regulation of protein transport GO:0051223 3 0.069
apoptotic process GO:0006915 116 0.068
regulation of nucleocytoplasmic transport GO:0046822 2 0.068
embryonic organ morphogenesis GO:0048562 274 0.067
pericardium development GO:0060039 1 0.067
negative regulation of cellular metabolic process GO:0031324 77 0.066
Zebrafish Mouse
axonal defasciculation GO:0007414 2 0.065
response to decreased oxygen levels GO:0036293 25 0.065
regulation of synapse organization GO:0050807 3 0.065
regulation of rna metabolic process GO:0051252 224 0.065
muscle cell development GO:0055001 115 0.065
vasculature development GO:0001944 278 0.065
nuclear transport GO:0051169 4 0.065
regulation of intracellular protein transport GO:0033157 3 0.065
regulation of cell communication GO:0010646 232 0.065
Zebrafish
cellular carbohydrate metabolic process GO:0044262 4 0.064
regulation of reactive oxygen species metabolic process GO:2000377 2 0.064
neuronal action potential GO:0019228 18 0.064
response to oxygen containing compound GO:1901700 55 0.064
Zebrafish
negative regulation of multicellular organismal process GO:0051241 69 0.064
cell growth GO:0016049 57 0.063
regulation of binding GO:0051098 3 0.063
lipid storage GO:0019915 1 0.062
negative regulation of rna metabolic process GO:0051253 48 0.062
Zebrafish Mouse
positive regulation of transport GO:0051050 2 0.061
striated muscle cell differentiation GO:0051146 129 0.060
axon guidance GO:0007411 86 0.060
regulation of carbohydrate metabolic process GO:0006109 4 0.060
neural crest cell differentiation GO:0014033 72 0.060
cellular response to chemical stimulus GO:0070887 157 0.059
regulation of cell shape GO:0008360 1 0.059
cellular component assembly involved in morphogenesis GO:0010927 107 0.058
positive regulation of cell proliferation GO:0008284 15 0.058
Rat
single organism metabolic process GO:0044710 217 0.058
Rat
cell substrate adhesion GO:0031589 4 0.058
positive regulation of cell cycle GO:0045787 3 0.057
negative regulation of response to stimulus GO:0048585 104 0.056
Zebrafish
neuron projection morphogenesis GO:0048812 161 0.056
regulation of cell death GO:0010941 103 0.056
cell part morphogenesis GO:0032990 246 0.055
negative regulation of macromolecule metabolic process GO:0010605 76 0.055
Zebrafish Mouse
response to lipid GO:0033993 60 0.055
Zebrafish
regulation of autophagy GO:0010506 3 0.055
extrinsic apoptotic signaling pathway GO:0097191 3 0.054
regulation of neuron differentiation GO:0045664 56 0.054
organelle organization GO:0006996 227 0.054
establishment of localization GO:0051234 244 0.053
regulation of epithelial cell proliferation GO:0050678 3 0.053
negative regulation of transcription dna templated GO:0045892 45 0.053
Zebrafish Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.053
Zebrafish Mouse
mesenchymal cell differentiation GO:0048762 87 0.053
positive regulation of map kinase activity GO:0043406 3 0.052
negative regulation of metabolic process GO:0009892 86 0.052
Zebrafish Mouse
gastrulation with mouth forming second GO:0001702 44 0.052
cellular ketone metabolic process GO:0042180 11 0.052
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.052
Zebrafish Mouse
actin polymerization or depolymerization GO:0008154 2 0.051
regulation of cell growth GO:0001558 29 0.051
transport GO:0006810 220 0.051
mesenchyme development GO:0060485 127 0.051
Zebrafish
sleep GO:0030431 1 0.051
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.050
phosphate containing compound metabolic process GO:0006796 108 0.050
hematopoietic or lymphoid organ development GO:0048534 191 0.050
regulation of multicellular organismal development GO:2000026 223 0.049
Rat
regulation of protein targeting GO:1903533 2 0.049
axonogenesis GO:0007409 152 0.049
negative regulation of molecular function GO:0044092 23 0.049
single organism transport GO:0044765 206 0.049
negative regulation of epithelial cell migration GO:0010633 1 0.049
regulation of myotube differentiation GO:0010830 2 0.048
segmentation GO:0035282 97 0.048
regulation of synapse assembly GO:0051963 3 0.048
cell projection assembly GO:0030031 64 0.047
amine metabolic process GO:0009308 2 0.047
protein targeting to nucleus GO:0044744 3 0.047
cellular protein modification process GO:0006464 100 0.047
regulation of cytoplasmic transport GO:1903649 4 0.046
regulation of epithelial to mesenchymal transition GO:0010717 3 0.046
single organism organelle organization GO:1902589 199 0.046
myotube differentiation GO:0014902 45 0.045
reactive oxygen species metabolic process GO:0072593 6 0.045
negative regulation of kinase activity GO:0033673 4 0.045
regulation of cell substrate adhesion GO:0010810 1 0.045
regulation of cell proliferation GO:0042127 37 0.045
Rat
defense response GO:0006952 47 0.045
death GO:0016265 121 0.045
positive regulation of signal transduction GO:0009967 56 0.044
morphogenesis of an epithelium GO:0002009 333 0.044
response to wounding GO:0009611 116 0.044
immune system process GO:0002376 241 0.044
regulation of organelle assembly GO:1902115 4 0.044
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.044
cellular response to molecule of bacterial origin GO:0071219 3 0.044
germ line stem cell maintenance GO:0030718 2 0.043
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.043
ensheathment of neurons GO:0007272 18 0.043
forebrain development GO:0030900 96 0.043
regulation of heart growth GO:0060420 2 0.043
determination of heart left right asymmetry GO:0061371 117 0.043
Zebrafish
regeneration GO:0031099 91 0.043
myeloid cell differentiation GO:0030099 86 0.043
protein import GO:0017038 3 0.043
thermosensory behavior GO:0040040 1 0.042
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.042
Zebrafish Mouse
response to hormone GO:0009725 48 0.041
Zebrafish
regulation of erk1 and erk2 cascade GO:0070372 4 0.041
midbrain development GO:0030901 28 0.041
positive regulation of cell adhesion GO:0045785 1 0.040
epithelial tube morphogenesis GO:0060562 148 0.040
muscle organ development GO:0007517 101 0.040
oxoacid metabolic process GO:0043436 31 0.040
enzyme linked receptor protein signaling pathway GO:0007167 106 0.040
Zebrafish
regulation of cellular protein metabolic process GO:0032268 52 0.039
regulation of cell development GO:0060284 100 0.039
muscle tissue development GO:0060537 110 0.039
positive regulation of muscle cell differentiation GO:0051149 1 0.039
regulation of membrane potential GO:0042391 23 0.039
positive regulation of stress activated mapk cascade GO:0032874 3 0.039
somitogenesis GO:0001756 87 0.039
specification of symmetry GO:0009799 204 0.039
Zebrafish
regulation of response to stimulus GO:0048583 269 0.039
Zebrafish
negative regulation of synapse assembly GO:0051964 2 0.038
mesenchymal cell development GO:0014031 78 0.038
cellular amine metabolic process GO:0044106 2 0.038
camera type eye development GO:0043010 222 0.038
negative regulation of cell communication GO:0010648 96 0.038
Zebrafish
somite development GO:0061053 96 0.038
response to fluid shear stress GO:0034405 2 0.037
cell surface receptor signaling pathway GO:0007166 325 0.037
Zebrafish
cell cell signaling GO:0007267 52 0.037
myeloid cell homeostasis GO:0002262 56 0.036
regulation of neurogenesis GO:0050767 87 0.036
retina morphogenesis in camera type eye GO:0060042 79 0.036
stem cell proliferation GO:0072089 4 0.036
biological adhesion GO:0022610 40 0.036
response to carbohydrate GO:0009743 3 0.036
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.036
response to corticosteroid GO:0031960 1 0.036
cell morphogenesis involved in differentiation GO:0000904 195 0.036
nucleoside phosphate biosynthetic process GO:1901293 21 0.036
cellular response to hypoxia GO:0071456 1 0.036
circadian sleep wake cycle sleep GO:0050802 1 0.035
photoreceptor cell fate specification GO:0043704 1 0.035
cell proliferation GO:0008283 80 0.035
Rat
epithelial cell differentiation GO:0030855 116 0.035
Mouse
protein metabolic process GO:0019538 183 0.035
axon development GO:0061564 166 0.035
phosphorus metabolic process GO:0006793 109 0.035
negative regulation of catabolic process GO:0009895 3 0.035
positive regulation of cell division GO:0051781 2 0.035
gland development GO:0048732 143 0.035
Zebrafish
neuron neuron synaptic transmission GO:0007270 1 0.034
regulation of establishment of protein localization GO:0070201 4 0.034
stem cell maintenance GO:0019827 4 0.034
cell projection morphogenesis GO:0048858 244 0.034
regulation of cellular amine metabolic process GO:0033238 0 0.034
regulation of signaling GO:0023051 235 0.034
Zebrafish
axon ensheathment GO:0008366 18 0.034
establishment of localization in cell GO:0051649 77 0.034
bmp signaling pathway GO:0030509 52 0.034
Zebrafish
erythrocyte homeostasis GO:0034101 55 0.034
hard palate development GO:0060022 4 0.033
embryonic heart tube development GO:0035050 133 0.033
visual perception GO:0007601 17 0.033
response to glucocorticoid GO:0051384 1 0.032
positive regulation of glucose import GO:0046326 1 0.032
neuroblast proliferation GO:0007405 2 0.032
positive regulation of developmental process GO:0051094 50 0.032
Rat
response to nutrient GO:0007584 3 0.031
regulation of apoptotic process GO:0042981 98 0.031
regulation of catalytic activity GO:0050790 55 0.031
circadian sleep wake cycle process GO:0022410 2 0.031
embryonic cranial skeleton morphogenesis GO:0048701 90 0.031
regulation of protein import into nucleus GO:0042306 2 0.031
regulation of dendrite development GO:0050773 3 0.031
adult behavior GO:0030534 2 0.031
macromolecular complex subunit organization GO:0043933 74 0.031
regulation of skeletal muscle fiber development GO:0048742 2 0.031
positive regulation of protein kinase b signaling GO:0051897 1 0.031
single organismal cell cell adhesion GO:0016337 29 0.031
positive regulation of epithelial cell proliferation GO:0050679 1 0.030
small molecule metabolic process GO:0044281 77 0.030
Rat
action potential GO:0001508 19 0.029
post embryonic organ development GO:0048569 4 0.029
actin filament based process GO:0030029 64 0.029
stem cell division GO:0017145 1 0.029
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.029
macroautophagy GO:0016236 1 0.029
regulation of dendrite morphogenesis GO:0048814 3 0.029
regulation of response to external stimulus GO:0032101 31 0.029
regulation of protein localization to nucleus GO:1900180 2 0.029
stem cell differentiation GO:0048863 117 0.029
nuclear export GO:0051168 1 0.029
response to hexose GO:0009746 3 0.029
nucleotide biosynthetic process GO:0009165 21 0.029
cell death GO:0008219 121 0.029
regulation of cardiac muscle tissue development GO:0055024 1 0.029
cellular amino acid metabolic process GO:0006520 7 0.029
purine ribonucleotide biosynthetic process GO:0009152 20 0.028
regulation of localization GO:0032879 104 0.028
regulation of growth GO:0040008 42 0.028
regulation of metal ion transport GO:0010959 4 0.028
regulation of cellular component organization GO:0051128 86 0.028
cell fate specification GO:0001708 68 0.028
striated muscle cell development GO:0055002 108 0.028
myelination GO:0042552 18 0.028
regulation of protein metabolic process GO:0051246 56 0.028
blood circulation GO:0008015 87 0.028
Mouse
lateral line system development GO:0048925 76 0.028
response to alkaloid GO:0043279 2 0.027
actin filament organization GO:0007015 15 0.027
adherens junction organization GO:0034332 4 0.027
negative regulation of cell differentiation GO:0045596 46 0.027
somatic muscle development GO:0007525 4 0.027
purine nucleotide biosynthetic process GO:0006164 20 0.027
cellular protein metabolic process GO:0044267 129 0.027
negative regulation of autophagy GO:0010507 1 0.027
g protein coupled receptor signaling pathway GO:0007186 74 0.027
cyclic nucleotide biosynthetic process GO:0009190 18 0.027
development of primary female sexual characteristics GO:0046545 4 0.027
cellular response to oxygen levels GO:0071453 1 0.027
organic acid metabolic process GO:0006082 31 0.026
sensory perception GO:0007600 39 0.026
Mouse
carbohydrate derivative biosynthetic process GO:1901137 43 0.026
cellular response to decreased oxygen levels GO:0036294 1 0.026
lateral line development GO:0048882 66 0.026
central nervous system projection neuron axonogenesis GO:0021952 15 0.026
homeostatic process GO:0042592 142 0.026
taxis GO:0042330 109 0.026
sensory perception of chemical stimulus GO:0007606 3 0.025
carboxylic acid metabolic process GO:0019752 22 0.025
regulation of cell projection assembly GO:0060491 4 0.025
regulation of protein binding GO:0043393 3 0.025
regulation of wnt signaling pathway GO:0030111 53 0.025
wound healing GO:0042060 90 0.025
programmed cell death GO:0012501 119 0.025
circadian sleep wake cycle GO:0042745 2 0.025
positive regulation of cell differentiation GO:0045597 30 0.025
Rat
response to monosaccharide GO:0034284 3 0.025
lymphocyte proliferation GO:0046651 1 0.025
phosphorylation GO:0016310 69 0.024
positive regulation of striated muscle tissue development GO:0045844 1 0.024
fin regeneration GO:0031101 51 0.024
nitric oxide metabolic process GO:0046209 2 0.024
female gonad development GO:0008585 4 0.024
apoptotic process involved in development GO:1902742 2 0.024
ear morphogenesis GO:0042471 64 0.024
negative regulation of cellular process GO:0048523 283 0.024
Zebrafish Mouse
skeletal system morphogenesis GO:0048705 102 0.024
embryonic pattern specification GO:0009880 44 0.023
response to oxygen levels GO:0070482 25 0.023
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.023
Zebrafish
inner ear morphogenesis GO:0042472 63 0.023
macromolecule localization GO:0033036 54 0.023
insulin like growth factor receptor signaling pathway GO:0048009 4 0.023
developmental pigmentation GO:0048066 48 0.023
neural precursor cell proliferation GO:0061351 20 0.023
regulation of response to extracellular stimulus GO:0032104 1 0.023
multi organism process GO:0051704 134 0.023
Mouse
cell fate commitment GO:0045165 99 0.023
regulation of cell morphogenesis GO:0022604 42 0.022
cyclic nucleotide metabolic process GO:0009187 18 0.022
anatomical structure homeostasis GO:0060249 36 0.022
response to glucose GO:0009749 3 0.022
metal ion transport GO:0030001 58 0.022
neural crest cell migration GO:0001755 42 0.022
cytokinesis GO:0000910 3 0.022
muscle cell differentiation GO:0042692 139 0.022
regulation of circadian sleep wake cycle GO:0042749 1 0.021
hindbrain development GO:0030902 91 0.021
Zebrafish
response to hypoxia GO:0001666 25 0.021
cyclic purine nucleotide metabolic process GO:0052652 18 0.021
immune system development GO:0002520 191 0.021
internal peptidyl lysine acetylation GO:0018393 2 0.021
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.021
regulation of cell activation GO:0050865 1 0.021
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.021
negative regulation of rna biosynthetic process GO:1902679 45 0.021
Zebrafish Mouse
regulation of protein complex assembly GO:0043254 3 0.021
regulation of cell matrix adhesion GO:0001952 1 0.021
sensory system development GO:0048880 76 0.021
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.021
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.021
cellular response to hormone stimulus GO:0032870 39 0.020
regulation of response to nutrient levels GO:0032107 1 0.020
single organism behavior GO:0044708 24 0.020
negative regulation of cytoplasmic transport GO:1903650 2 0.020
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.020
release of sequestered calcium ion into cytosol GO:0051209 3 0.020
meiotic nuclear division GO:0007126 4 0.020
cellular response to extracellular stimulus GO:0031668 2 0.020
blood vessel endothelial cell migration GO:0043534 18 0.020
interaction with host GO:0051701 4 0.020
protein modification process GO:0036211 100 0.020
lens development in camera type eye GO:0002088 22 0.020
negative regulation of apoptotic process GO:0043066 55 0.020
regulation of molecular function GO:0065009 70 0.020
negative regulation of intracellular protein transport GO:0090317 3 0.020
intracellular transport GO:0046907 32 0.020
cytoskeleton organization GO:0007010 96 0.020
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.020
regulation of skeletal muscle tissue development GO:0048641 4 0.020
peptidyl tyrosine phosphorylation GO:0018108 5 0.019
intracellular signal transduction GO:0035556 85 0.019
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.019
developmental growth involved in morphogenesis GO:0060560 86 0.019
ribonucleotide biosynthetic process GO:0009260 20 0.019
cellular response to starvation GO:0009267 1 0.019
locomotor rhythm GO:0045475 3 0.019
eye morphogenesis GO:0048592 144 0.019
regulation of neural precursor cell proliferation GO:2000177 3 0.019
regulation of programmed cell death GO:0043067 101 0.019
regulation of organ morphogenesis GO:2000027 35 0.019
negative regulation of chemotaxis GO:0050922 4 0.019
peptide transport GO:0015833 1 0.019
cell matrix adhesion GO:0007160 4 0.019
negative regulation of defense response GO:0031348 2 0.019
lateral inhibition GO:0046331 1 0.019
embryonic heart tube morphogenesis GO:0003143 108 0.019
regulation of protein phosphorylation GO:0001932 18 0.019
regulation of growth rate GO:0040009 1 0.019
cellular response to radiation GO:0071478 4 0.018
cellular response to organic substance GO:0071310 105 0.018
blood vessel development GO:0001568 246 0.018

thrb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.058
Human
retinal disease DOID:5679 0 0.046
retinal degeneration DOID:8466 0 0.046
sensory system disease DOID:0050155 0 0.046
eye and adnexa disease DOID:1492 0 0.046
nervous system disease DOID:863 0 0.046
eye disease DOID:5614 0 0.046
retinitis pigmentosa DOID:10584 0 0.025