Danio rerio

0 known processes

tial1

TIA1 cytotoxic granule-associated RNA binding protein-like 1

(Aliases: MGC66130,zgc:66130)

tial1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular macromolecule metabolic process GO:0044260 391 0.403
Yeast Fly
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.355
Fly
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.307
Fly
regulation of gene expression GO:0010468 265 0.216
Yeast Fly
nucleobase containing compound metabolic process GO:0006139 274 0.168
Yeast Fly
regulation of mrna splicing via spliceosome GO:0048024 3 0.152
Fly
regulation of mrna processing GO:0050684 3 0.148
Fly
larval development GO:0002164 2 0.147
Worm
regulation of cellular metabolic process GO:0031323 320 0.143
Fly
regulation of primary metabolic process GO:0080090 311 0.122
Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.111
Yeast Fly
endosomal transport GO:0016197 2 0.109
regulation of macromolecule metabolic process GO:0060255 317 0.105
Yeast Fly
modification dependent macromolecule catabolic process GO:0043632 3 0.095
signal transduction GO:0007165 455 0.095
regulation of rna metabolic process GO:0051252 224 0.091
Fly
proteasomal protein catabolic process GO:0010498 2 0.090
negative regulation of cellular process GO:0048523 283 0.079
ubiquitin dependent protein catabolic process GO:0006511 3 0.079
positive regulation of cellular process GO:0048522 201 0.077
Mouse
alternative mrna splicing via spliceosome GO:0000380 1 0.076
Fly
organic substance biosynthetic process GO:1901576 289 0.067
nitrogen compound metabolic process GO:0006807 319 0.065
Yeast Fly
rna localization GO:0006403 4 0.064
microtubule organizing center organization GO:0031023 1 0.064
maintenance of location GO:0051235 4 0.064
heterocycle metabolic process GO:0046483 290 0.062
Yeast Fly
intracellular signal transduction GO:0035556 85 0.061
regulation of biosynthetic process GO:0009889 250 0.060
organic cyclic compound biosynthetic process GO:1901362 223 0.059
nuclear migration GO:0007097 3 0.059
cellular nitrogen compound biosynthetic process GO:0044271 218 0.058
stem cell maintenance GO:0019827 4 0.058
positive regulation of biological process GO:0048518 253 0.057
Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.056
Yeast Fly
regulation of transcription dna templated GO:0006355 213 0.055
organic cyclic compound metabolic process GO:1901360 301 0.055
Yeast Fly
cellular macromolecule biosynthetic process GO:0034645 224 0.052
mrna export from nucleus GO:0006406 1 0.051
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.050
cellular biosynthetic process GO:0044249 286 0.050
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.049
lipid storage GO:0019915 1 0.049
regulation of protein ubiquitination GO:0031396 3 0.049
centrosome organization GO:0051297 1 0.048
double strand break repair GO:0006302 3 0.047
regulation of response to stimulus GO:0048583 269 0.047
cell substrate adhesion GO:0031589 4 0.047
regulation of rna biosynthetic process GO:2001141 213 0.046
regulation of cellular biosynthetic process GO:0031326 245 0.044
mrna metabolic process GO:0016071 20 0.043
Yeast Fly
nuclear transport GO:0051169 4 0.043
cellular protein catabolic process GO:0044257 4 0.042
negative regulation of biological process GO:0048519 304 0.042
regulation of biological quality GO:0065008 263 0.041
Yeast
immune system process GO:0002376 241 0.041
biosynthetic process GO:0009058 294 0.041
hemopoiesis GO:0030097 183 0.041
gene expression GO:0010467 252 0.040
Yeast Fly
response to stress GO:0006950 263 0.040
regulation of dna templated transcription in response to stress GO:0043620 0 0.039
cell surface receptor signaling pathway GO:0007166 325 0.039
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.039
protein metabolic process GO:0019538 183 0.039
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.038
centrosome cycle GO:0007098 1 0.038
positive regulation of metabolic process GO:0009893 108 0.038
rna metabolic process GO:0016070 219 0.037
Yeast Fly
protein k48 linked ubiquitination GO:0070936 1 0.037
heterocycle biosynthetic process GO:0018130 215 0.036
nucleic acid templated transcription GO:0097659 181 0.036
phagocytosis GO:0006909 3 0.036
cellular protein metabolic process GO:0044267 129 0.035
protein polyubiquitination GO:0000209 4 0.035
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.035
immune system development GO:0002520 191 0.035
muscle cell differentiation GO:0042692 139 0.035
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.033
positive regulation of catabolic process GO:0009896 4 0.033
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.032
response to chemical GO:0042221 320 0.032
carbohydrate biosynthetic process GO:0016051 1 0.032
regulation of signal transduction GO:0009966 225 0.031
aging GO:0007568 2 0.031
guanosine containing compound metabolic process GO:1901068 4 0.031
nucleic acid metabolic process GO:0090304 244 0.030
Yeast Fly
translational initiation GO:0006413 3 0.030
transcription dna templated GO:0006351 181 0.030
gtp catabolic process GO:0006184 2 0.030
protein import GO:0017038 3 0.030
negative regulation of chromosome organization GO:2001251 1 0.029
negative regulation of metabolic process GO:0009892 86 0.029
regulation of protein catabolic process GO:0042176 1 0.028
single organism metabolic process GO:0044710 217 0.028
modification dependent protein catabolic process GO:0019941 3 0.027
regulation of macromolecule biosynthetic process GO:0010556 225 0.027
protein polymerization GO:0051258 4 0.026
nucleobase containing compound biosynthetic process GO:0034654 205 0.026
negative regulation of catabolic process GO:0009895 3 0.026
response to drug GO:0042493 3 0.026
regulation of nucleic acid templated transcription GO:1903506 213 0.026
regulation of nitrogen compound metabolic process GO:0051171 251 0.026
Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.025
positive regulation of signal transduction GO:0009967 56 0.025
cellular response to starvation GO:0009267 1 0.025
rna biosynthetic process GO:0032774 181 0.024
regulation of erk1 and erk2 cascade GO:0070372 4 0.024
transport GO:0006810 220 0.024
positive regulation of muscle cell differentiation GO:0051149 1 0.024
golgi vesicle transport GO:0048193 3 0.024
regulation of cell differentiation GO:0045595 142 0.024
regulation of autophagy GO:0010506 3 0.023
protein secretion GO:0009306 1 0.023
production of molecular mediator of immune response GO:0002440 2 0.023
positive regulation of ras protein signal transduction GO:0046579 1 0.023
negative regulation of cytoplasmic transport GO:1903650 2 0.023
protein import into nucleus GO:0006606 3 0.023
secondary metabolic process GO:0019748 3 0.023
protein stabilization GO:0050821 2 0.022
regulation of metabolic process GO:0019222 359 0.022
Yeast Fly
intracellular estrogen receptor signaling pathway GO:0030520 3 0.022
autophagy GO:0006914 4 0.022
germ line stem cell maintenance GO:0030718 2 0.022
positive regulation of apoptotic process GO:0043065 29 0.022
protein localization to nucleus GO:0034504 3 0.022
ribosomal small subunit biogenesis GO:0042274 2 0.022
regulation of cell communication GO:0010646 232 0.022
positive regulation of apoptotic signaling pathway GO:2001235 1 0.022
positive regulation of cellular catabolic process GO:0031331 3 0.021
positive regulation of response to stimulus GO:0048584 80 0.021
macromolecular complex subunit organization GO:0043933 74 0.021
Yeast
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.021
pole plasm assembly GO:0007315 4 0.021
peptide transport GO:0015833 1 0.021
regulation of cell substrate adhesion GO:0010810 1 0.021
regulation of gtp catabolic process GO:0033124 2 0.021
regulation of anatomical structure morphogenesis GO:0022603 130 0.021
regulation of cellular ketone metabolic process GO:0010565 7 0.021
regulation of cell death GO:0010941 103 0.021
regulation of cell development GO:0060284 100 0.021
nuclear import GO:0051170 3 0.021
hormone transport GO:0009914 2 0.020
neuroblast proliferation GO:0007405 2 0.020
regulation of apoptotic process GO:0042981 98 0.020
positive regulation of macromolecule metabolic process GO:0010604 93 0.020
rna splicing GO:0008380 16 0.020
Fly
regulation of production of molecular mediator of immune response GO:0002700 1 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.020
gtp metabolic process GO:0046039 4 0.020
negative regulation of protein complex assembly GO:0031333 1 0.020
cell cycle process GO:0022402 53 0.020
nucleic acid transport GO:0050657 2 0.020
regulation of reproductive process GO:2000241 4 0.020
positive regulation of neuron apoptotic process GO:0043525 1 0.019
regulation of multicellular organism growth GO:0040014 4 0.019
erk1 and erk2 cascade GO:0070371 4 0.019
nucleocytoplasmic transport GO:0006913 4 0.019
small gtpase mediated signal transduction GO:0007264 8 0.019
death GO:0016265 121 0.019
regulation of cell shape GO:0008360 1 0.019
single organism organelle organization GO:1902589 199 0.019
response to hexose GO:0009746 3 0.019
positive regulation of transport GO:0051050 2 0.019
cell cycle g2 m phase transition GO:0044839 4 0.019
cellular ketone metabolic process GO:0042180 11 0.018
carbohydrate homeostasis GO:0033500 1 0.018
positive regulation of cell cycle GO:0045787 3 0.018
apoptotic process GO:0006915 116 0.018
regulation of establishment of protein localization GO:0070201 4 0.018
regulation of microtubule cytoskeleton organization GO:0070507 3 0.018
activation of mapk activity GO:0000187 3 0.018
regulation of cell activation GO:0050865 1 0.018
macromolecule biosynthetic process GO:0009059 227 0.018
negative regulation of histone modification GO:0031057 1 0.018
stem cell proliferation GO:0072089 4 0.018
heart development GO:0007507 313 0.018
rna export from nucleus GO:0006405 1 0.018
stem cell differentiation GO:0048863 117 0.018
negative regulation of gene expression GO:0010629 65 0.017
nephron epithelium morphogenesis GO:0072088 1 0.017
macromolecule modification GO:0043412 111 0.017
hematopoietic or lymphoid organ development GO:0048534 191 0.017
positive regulation of map kinase activity GO:0043406 3 0.017
ras protein signal transduction GO:0007265 7 0.017
guanosine containing compound catabolic process GO:1901069 2 0.017
mrna transport GO:0051028 2 0.017
programmed cell death GO:0012501 119 0.017
regulation of defense response to virus by host GO:0050691 1 0.017
regulation of protein transport GO:0051223 3 0.017
protein modification process GO:0036211 100 0.017
antimicrobial humoral response GO:0019730 2 0.017
regulation of wound healing GO:0061041 2 0.017
positive regulation of stress activated mapk cascade GO:0032874 3 0.017
meiotic nuclear division GO:0007126 4 0.017
extrinsic apoptotic signaling pathway GO:0097191 3 0.017
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.017
microtubule cytoskeleton organization GO:0000226 33 0.017
positive regulation of leukocyte differentiation GO:1902107 1 0.017
regulation of purine nucleotide catabolic process GO:0033121 2 0.016
mitotic dna damage checkpoint GO:0044773 4 0.016
anterior posterior pattern specification GO:0009952 152 0.016
cognition GO:0050890 1 0.016
nucleobase containing compound transport GO:0015931 2 0.016
pronuclear migration GO:0035046 1 0.016
positive regulation of stem cell proliferation GO:2000648 1 0.016
renal tubule morphogenesis GO:0061333 1 0.016
limb bud formation GO:0060174 2 0.016
negative regulation of protein phosphorylation GO:0001933 4 0.016
protein modification by small protein conjugation or removal GO:0070647 14 0.016
positive regulation of programmed cell death GO:0043068 29 0.016
macroautophagy GO:0016236 1 0.016
protein targeting to nucleus GO:0044744 3 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
positive regulation of translation GO:0045727 1 0.015
regulation of photoreceptor cell differentiation GO:0046532 2 0.015
regulation of rna splicing GO:0043484 8 0.015
Fly
regulation of developmental process GO:0050793 247 0.015
positive regulation of wound healing GO:0090303 1 0.015
hormone secretion GO:0046879 2 0.015
cellular component morphogenesis GO:0032989 336 0.015
blood vessel development GO:0001568 246 0.015
transcription from rna polymerase ii promoter GO:0006366 80 0.015
protein modification by small protein conjugation GO:0032446 13 0.015
hatching GO:0035188 4 0.015
mitochondrion organization GO:0007005 4 0.015
liver development GO:0001889 96 0.015
phagocytosis engulfment GO:0006911 1 0.015
positive regulation of neuron death GO:1901216 1 0.015
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.015
cellular amine metabolic process GO:0044106 2 0.015
regulation of signaling GO:0023051 235 0.015
stem cell development GO:0048864 82 0.015
nuclear export GO:0051168 1 0.015
cytoskeleton organization GO:0007010 96 0.015
muscle structure development GO:0061061 196 0.015
single organism transport GO:0044765 206 0.014
g1 s transition of mitotic cell cycle GO:0000082 1 0.014
regulation of organ growth GO:0046620 3 0.014
positive regulation of dna templated transcription elongation GO:0032786 1 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
atp catabolic process GO:0006200 4 0.014
chordate embryonic development GO:0043009 271 0.014
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 10 0.014
Fly
amine metabolic process GO:0009308 2 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.014
biological adhesion GO:0022610 40 0.014
positive regulation of cellular metabolic process GO:0031325 94 0.014
negative regulation of cellular metabolic process GO:0031324 77 0.014
cell death GO:0008219 121 0.014
aromatic compound biosynthetic process GO:0019438 217 0.014
negative regulation of epithelial cell proliferation GO:0050680 1 0.014
regulation of carbohydrate metabolic process GO:0006109 4 0.014
organism emergence from protective structure GO:0071684 4 0.014
morphogenesis of an epithelium GO:0002009 333 0.014
response to organic substance GO:0010033 153 0.014
g2 m transition of mitotic cell cycle GO:0000086 4 0.014
mrna processing GO:0006397 14 0.014
Fly
regulation of tube size GO:0035150 2 0.014
organic acid metabolic process GO:0006082 31 0.014
regulation of chromosome segregation GO:0051983 1 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
blood vessel morphogenesis GO:0048514 216 0.013
regulation of neural precursor cell proliferation GO:2000177 3 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
positive regulation of cell death GO:0010942 29 0.013
cytoskeleton dependent cytokinesis GO:0061640 3 0.013
regulation of hormone secretion GO:0046883 2 0.013
regulation of cytoplasmic transport GO:1903649 4 0.013
regulation of response to biotic stimulus GO:0002831 2 0.013
positive regulation of dna metabolic process GO:0051054 1 0.013
regulation of multicellular organismal development GO:2000026 223 0.013
cellular component disassembly GO:0022411 1 0.013
regulation of cytokine production GO:0001817 3 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.013
cell matrix adhesion GO:0007160 4 0.013
cellular response to extracellular stimulus GO:0031668 2 0.013
regulation of calcium ion transport GO:0051924 2 0.013
peptidyl serine modification GO:0018209 2 0.013
phosphate containing compound metabolic process GO:0006796 108 0.013
skeletal muscle organ development GO:0060538 78 0.013
cellular carbohydrate metabolic process GO:0044262 4 0.012
male meiosis GO:0007140 2 0.012
regulation of organelle assembly GO:1902115 4 0.012
apoptotic process involved in development GO:1902742 2 0.012
nucleoside monophosphate catabolic process GO:0009125 4 0.012
negative regulation of dna metabolic process GO:0051053 4 0.012
regulation of carbohydrate biosynthetic process GO:0043255 1 0.012
positive regulation of secretion GO:0051047 1 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.012
gland development GO:0048732 143 0.012
membrane invagination GO:0010324 1 0.012
positive regulation of gtp catabolic process GO:0033126 1 0.012
ribonucleoside monophosphate catabolic process GO:0009158 4 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
regulation of programmed cell death GO:0043067 101 0.012
microtubule based process GO:0007017 60 0.012
peptidyl serine phosphorylation GO:0018105 1 0.012
recombinational repair GO:0000725 1 0.012
mononuclear cell proliferation GO:0032943 1 0.012
telomere maintenance GO:0000723 1 0.012
cellular response to nutrient levels GO:0031669 2 0.012
fertilization GO:0009566 3 0.012
regulation of dendrite development GO:0050773 3 0.012
regionalization GO:0003002 274 0.012
multicellular organism growth GO:0035264 4 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.012
homeostatic process GO:0042592 142 0.012
regulation of blood pressure GO:0008217 1 0.012
oxidative phosphorylation GO:0006119 1 0.012
cell proliferation GO:0008283 80 0.012
Mouse
regulation of mrna metabolic process GO:1903311 6 0.012
Fly
establishment of rna localization GO:0051236 3 0.012
cell projection morphogenesis GO:0048858 244 0.012
regulation of multicellular organismal process GO:0051239 277 0.012
rna splicing via transesterification reactions GO:0000375 10 0.012
Fly
regulation of protein polymerization GO:0032271 2 0.012
positive regulation of cell communication GO:0010647 56 0.012
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.012
negative regulation of gliogenesis GO:0014014 1 0.012
segmentation GO:0035282 97 0.012
regulation of dendrite morphogenesis GO:0048814 3 0.012
positive regulation of cellular component biogenesis GO:0044089 3 0.012
histone phosphorylation GO:0016572 2 0.011
regulation of intracellular signal transduction GO:1902531 57 0.011
negative regulation of autophagy GO:0010507 1 0.011
cellular response to dna damage stimulus GO:0006974 24 0.011
sex determination GO:0007530 1 0.011
establishment of protein localization to organelle GO:0072594 4 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
single organism membrane fusion GO:0044801 2 0.011
cell cycle g1 s phase transition GO:0044843 1 0.011
positive regulation of multi organism process GO:0043902 3 0.011
response to carbohydrate GO:0009743 3 0.011
nephron morphogenesis GO:0072028 2 0.011
cellular response to oxygen levels GO:0071453 1 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
negative regulation of protein transport GO:0051224 3 0.011
peptide metabolic process GO:0006518 1 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
regulation of circadian rhythm GO:0042752 4 0.011
regulation of response to oxidative stress GO:1902882 2 0.011
methylation GO:0032259 22 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
response to lipid GO:0033993 60 0.011
regulation of epidermis development GO:0045682 2 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.011
establishment of localization GO:0051234 244 0.011
negative regulation of i kappab kinase nf kappab signaling GO:0043124 1 0.011
regulation of systemic arterial blood pressure GO:0003073 1 0.011
cortical cytoskeleton organization GO:0030865 1 0.011
regulation of epithelial cell proliferation GO:0050678 3 0.010
cytoplasm organization GO:0007028 4 0.010
regulation of oocyte development GO:0060281 3 0.010
cellular response to organic substance GO:0071310 105 0.010
cytokinesis GO:0000910 3 0.010
lipid homeostasis GO:0055088 3 0.010
regulation of cell cycle GO:0051726 52 0.010
positive regulation of cytokine production GO:0001819 2 0.010
protein localization to plasma membrane GO:0072659 1 0.010
positive regulation of signaling GO:0023056 56 0.010
cellular response to decreased oxygen levels GO:0036294 1 0.010
intracellular mrna localization GO:0008298 1 0.010
hepaticobiliary system development GO:0061008 98 0.010
somatic muscle development GO:0007525 4 0.010
cellular protein modification process GO:0006464 100 0.010
regulation of stem cell proliferation GO:0072091 2 0.010
chemosensory behavior GO:0007635 1 0.010
cellular amino acid metabolic process GO:0006520 7 0.010
negative regulation of kinase activity GO:0033673 4 0.010
oxoacid metabolic process GO:0043436 31 0.010
peptidyl threonine phosphorylation GO:0018107 1 0.010
purine nucleoside monophosphate catabolic process GO:0009128 4 0.010
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.010
single organism localization GO:1902578 225 0.010
locomotor rhythm GO:0045475 3 0.010
response to other organism GO:0051707 97 0.010
organelle organization GO:0006996 227 0.010
Yeast

tial1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
musculoskeletal system disease DOID:17 0 0.022
muscular disease DOID:0080000 0 0.013
muscle tissue disease DOID:66 0 0.013
myopathy DOID:423 0 0.012