Danio rerio

10 known processes

tjp3

tight junction protein 3

(Aliases: wu:fj93c08,cb766)

tjp3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular macromolecule biosynthetic process GO:0034645 224 0.579
oxoacid metabolic process GO:0043436 31 0.343
liver development GO:0001889 96 0.297
s adenosylmethionine metabolic process GO:0046500 1 0.264
regulation of nucleic acid templated transcription GO:1903506 213 0.251
regulation of primary metabolic process GO:0080090 311 0.212
cell surface receptor signaling pathway GO:0007166 325 0.211
modification dependent protein catabolic process GO:0019941 3 0.201
cell projection organization GO:0030030 284 0.196
vasculature development GO:0001944 278 0.191
digestive tract development GO:0048565 265 0.189
organic acid metabolic process GO:0006082 31 0.180
cellular protein modification process GO:0006464 100 0.173
cellular macromolecule metabolic process GO:0044260 391 0.172
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.164
regulation of gene expression GO:0010468 265 0.164
biosynthetic process GO:0009058 294 0.154
organic cyclic compound biosynthetic process GO:1901362 223 0.152
organic cyclic compound metabolic process GO:1901360 301 0.146
carboxylic acid metabolic process GO:0019752 22 0.139
nitrogen compound metabolic process GO:0006807 319 0.138
heterocycle biosynthetic process GO:0018130 215 0.126
cell adhesion GO:0007155 40 0.123
biological adhesion GO:0022610 40 0.118
macromolecule biosynthetic process GO:0009059 227 0.116
gastrulation GO:0007369 208 0.114
hepaticobiliary system development GO:0061008 98 0.114
rna metabolic process GO:0016070 219 0.113
nucleobase containing compound metabolic process GO:0006139 274 0.108
regulation of rna biosynthetic process GO:2001141 213 0.101
small molecule metabolic process GO:0044281 77 0.093
organic substance biosynthetic process GO:1901576 289 0.093
very long chain fatty acid biosynthetic process GO:0042761 4 0.088
cellular aromatic compound metabolic process GO:0006725 295 0.086
regulation of rna metabolic process GO:0051252 224 0.085
adherens junction organization GO:0034332 4 0.085
regulation of stem cell proliferation GO:0072091 2 0.085
nucleic acid metabolic process GO:0090304 244 0.082
single fertilization GO:0007338 3 0.082
single organism metabolic process GO:0044710 217 0.081
cellular component assembly GO:0022607 170 0.080
transcription dna templated GO:0006351 181 0.078
heterocycle metabolic process GO:0046483 290 0.077
cellular response to extracellular stimulus GO:0031668 2 0.077
digestive system development GO:0055123 289 0.076
heart looping GO:0001947 94 0.072
regulation of metabolic process GO:0019222 359 0.071
regulation of transcription dna templated GO:0006355 213 0.067
cellular nitrogen compound metabolic process GO:0034641 290 0.065
regulation of cellular metabolic process GO:0031323 320 0.062
blood circulation GO:0008015 87 0.062
regulation of macromolecule metabolic process GO:0060255 317 0.061
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.059
aromatic compound biosynthetic process GO:0019438 217 0.058
signal transduction GO:0007165 455 0.058
cellular protein metabolic process GO:0044267 129 0.056
cell junction organization GO:0034330 11 0.055
regulation of multicellular organismal process GO:0051239 277 0.054
heart morphogenesis GO:0003007 156 0.053
innervation GO:0060384 3 0.053
larval development GO:0002164 2 0.052
regulation of macromolecule biosynthetic process GO:0010556 225 0.050
morphogenesis of an epithelium GO:0002009 333 0.050
regulation of cellular ketone metabolic process GO:0010565 7 0.050
neuron projection morphogenesis GO:0048812 161 0.049
protein modification process GO:0036211 100 0.048
cell death GO:0008219 121 0.048
muscle cell differentiation GO:0042692 139 0.048
establishment of cell polarity involved in mesendodermal cell migration GO:0003369 1 0.046
endoderm development GO:0007492 49 0.046
regulation of embryonic development GO:0045995 47 0.046
cellular modified amino acid metabolic process GO:0006575 3 0.046
cell morphogenesis GO:0000902 289 0.046
cellular amino acid metabolic process GO:0006520 7 0.046
rna biosynthetic process GO:0032774 181 0.045
regulation of biosynthetic process GO:0009889 250 0.045
long chain fatty acid metabolic process GO:0001676 1 0.045
cellular biosynthetic process GO:0044249 286 0.044
generation of neurons GO:0048699 385 0.044
regulation of cytoplasmic transport GO:1903649 4 0.044
macromolecule modification GO:0043412 111 0.042
cell cell adhesion involved in mesendodermal cell migration GO:0003370 1 0.042
neuron projection development GO:0031175 180 0.041
cell part morphogenesis GO:0032990 246 0.041
protein metabolic process GO:0019538 183 0.041
eye development GO:0001654 277 0.041
blood vessel morphogenesis GO:0048514 216 0.041
fatty acid elongation GO:0030497 1 0.041
organelle localization GO:0051640 49 0.040
digestive tract morphogenesis GO:0048546 231 0.040
cellular nitrogen compound biosynthetic process GO:0044271 218 0.040
transcription from rna polymerase ii promoter GO:0006366 80 0.039
organonitrogen compound metabolic process GO:1901564 74 0.039
regulation of nitrogen compound metabolic process GO:0051171 251 0.038
cellular carbohydrate metabolic process GO:0044262 4 0.038
cell cell junction organization GO:0045216 10 0.038
nucleocytoplasmic transport GO:0006913 4 0.038
epithelial cell morphogenesis GO:0003382 2 0.037
regulation of cellular biosynthetic process GO:0031326 245 0.037
nucleobase containing compound biosynthetic process GO:0034654 205 0.036
long chain fatty acid biosynthetic process GO:0042759 1 0.034
regulation of dna templated transcription in response to stress GO:0043620 0 0.034
cellular component biogenesis GO:0044085 178 0.033
positive regulation of cell adhesion GO:0045785 1 0.033
cellular component morphogenesis GO:0032989 336 0.033
developmental maturation GO:0021700 34 0.033
embryonic heart tube development GO:0035050 133 0.032
regulation of anatomical structure morphogenesis GO:0022603 130 0.032
erk1 and erk2 cascade GO:0070371 4 0.031
muscle cell development GO:0055001 115 0.030
circulatory system process GO:0003013 87 0.030
aging GO:0007568 2 0.029
positive regulation of macromolecule metabolic process GO:0010604 93 0.029
sensory perception GO:0007600 39 0.029
fertilization GO:0009566 3 0.028
maintenance of location GO:0051235 4 0.028
regulation of carbohydrate metabolic process GO:0006109 4 0.028
negative regulation of protein kinase activity GO:0006469 4 0.028
cell migration GO:0016477 237 0.028
nucleic acid templated transcription GO:0097659 181 0.028
blood vessel development GO:0001568 246 0.028
macromolecular complex disassembly GO:0032984 1 0.027
positive regulation of rna biosynthetic process GO:1902680 57 0.027
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016339 2 0.027
regulation of glucose transport GO:0010827 1 0.027
cell morphogenesis involved in differentiation GO:0000904 195 0.026
cellular response to external stimulus GO:0071496 2 0.026
nuclear migration GO:0007097 3 0.026
regulation of organ growth GO:0046620 3 0.025
regulation of establishment of protein localization GO:0070201 4 0.025
regulation of multicellular organismal development GO:2000026 223 0.025
regionalization GO:0003002 274 0.024
positive regulation of translation GO:0045727 1 0.024
cellular response to starvation GO:0009267 1 0.024
neuron differentiation GO:0030182 353 0.024
system process GO:0003008 185 0.023
cardiac muscle tissue development GO:0048738 48 0.023
chordate embryonic development GO:0043009 271 0.023
cellular ketone metabolic process GO:0042180 11 0.023
cell projection morphogenesis GO:0048858 244 0.022
fatty acid elongation unsaturated fatty acid GO:0019368 1 0.022
determination of left right symmetry GO:0007368 179 0.022
regulation of blood circulation GO:1903522 32 0.022
regulation of cell matrix adhesion GO:0001952 1 0.021
positive regulation of epithelial cell migration GO:0010634 2 0.021
protein acetylation GO:0006473 2 0.021
tight junction assembly GO:0070830 1 0.021
reproduction GO:0000003 40 0.020
regulation of cell death GO:0010941 103 0.020
epithelial tube morphogenesis GO:0060562 148 0.020
neuron development GO:0048666 262 0.019
actin filament based process GO:0030029 64 0.019
single organism cell adhesion GO:0098602 29 0.019
regulation of protein transport GO:0051223 3 0.019
multi organism reproductive process GO:0044703 36 0.019
regulation of intracellular protein transport GO:0033157 3 0.018
cell proliferation GO:0008283 80 0.018
negative regulation of dna replication GO:0008156 2 0.018
specification of symmetry GO:0009799 204 0.018
negative regulation of protein phosphorylation GO:0001933 4 0.018
cellular protein catabolic process GO:0044257 4 0.018
regulation of nucleocytoplasmic transport GO:0046822 2 0.018
anterior posterior axis specification GO:0009948 20 0.018
synaptic vesicle transport GO:0048489 1 0.018
regulation of molecular function GO:0065009 70 0.018
macromolecule localization GO:0033036 54 0.017
peptidyl serine phosphorylation GO:0018105 1 0.017
protein complex disassembly GO:0043241 1 0.017
sensory organ development GO:0007423 393 0.017
adherens junction maintenance GO:0034334 2 0.017
regulation of biological quality GO:0065008 263 0.017
kupffer s vesicle development GO:0070121 50 0.017
multi organism process GO:0051704 134 0.017
regulation of metal ion transport GO:0010959 4 0.017
negative regulation of epithelial cell proliferation GO:0050680 1 0.017
regulation of cellular protein metabolic process GO:0032268 52 0.016
striated muscle cell differentiation GO:0051146 129 0.016
death GO:0016265 121 0.016
cell maturation GO:0048469 23 0.016
lipid storage GO:0019915 1 0.016
positive regulation of cellular biosynthetic process GO:0031328 68 0.016
negative regulation of dna metabolic process GO:0051053 4 0.016
sensory organ morphogenesis GO:0090596 200 0.016
negative regulation of stem cell differentiation GO:2000737 2 0.015
positive regulation of biological process GO:0048518 253 0.015
endosome organization GO:0007032 2 0.015
glucocorticoid metabolic process GO:0008211 2 0.015
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.015
odontogenesis of dentin containing tooth GO:0042475 1 0.015
cell junction maintenance GO:0034331 2 0.014
muscle tissue development GO:0060537 110 0.014
regulation of cardiac muscle tissue development GO:0055024 1 0.014
detection of stimulus GO:0051606 29 0.014
establishment of organelle localization GO:0051656 45 0.014
regulation of organ morphogenesis GO:2000027 35 0.014
organelle assembly GO:0070925 110 0.014
action potential GO:0001508 19 0.013
convergent extension GO:0060026 118 0.013
determination of bilateral symmetry GO:0009855 204 0.013
axonogenesis GO:0007409 152 0.013
golgi vesicle transport GO:0048193 3 0.013
proteasomal protein catabolic process GO:0010498 2 0.013
response to decreased oxygen levels GO:0036293 25 0.013
vesicle localization GO:0051648 27 0.013
carbohydrate derivative metabolic process GO:1901135 61 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.012
heart development GO:0007507 313 0.012
regulation of cell development GO:0060284 100 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.012
negative regulation of kinase activity GO:0033673 4 0.012
regulation of dna templated transcription elongation GO:0032784 3 0.012
muscle structure development GO:0061061 196 0.012
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.012
regulation of protein localization to nucleus GO:1900180 2 0.012
carbohydrate derivative biosynthetic process GO:1901137 43 0.012
response to chemical GO:0042221 320 0.012
response to drug GO:0042493 3 0.011
regulation of heart growth GO:0060420 2 0.011
protein import GO:0017038 3 0.011
sulfur compound metabolic process GO:0006790 13 0.011
negative regulation of biological process GO:0048519 304 0.011
endocrine hormone secretion GO:0060986 2 0.011
eye morphogenesis GO:0048592 144 0.011
regulation of establishment of planar polarity GO:0090175 4 0.011
nuclear transport GO:0051169 4 0.011
single organismal cell cell adhesion GO:0016337 29 0.011
gland development GO:0048732 143 0.011
locomotion GO:0040011 313 0.011
positive regulation of secretion by cell GO:1903532 1 0.011
notochord development GO:0030903 54 0.011
retina morphogenesis in camera type eye GO:0060042 79 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
cellular component assembly involved in morphogenesis GO:0010927 107 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
multicellular organismal water homeostasis GO:0050891 1 0.010
internal protein amino acid acetylation GO:0006475 2 0.010
lipid biosynthetic process GO:0008610 22 0.010
regulation of blood pressure GO:0008217 1 0.010
central nervous system development GO:0007417 387 0.010
regulation of eye photoreceptor cell development GO:0042478 2 0.010
response to oxygen levels GO:0070482 25 0.010
cellular response to nutrient levels GO:0031669 2 0.010

tjp3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
intrinsic cardiomyopathy DOID:0060036 0 0.070
muscular disease DOID:0080000 0 0.070
heart disease DOID:114 0 0.070
cardiovascular system disease DOID:1287 0 0.070
disease of anatomical entity DOID:7 0 0.070
muscle tissue disease DOID:66 0 0.070
musculoskeletal system disease DOID:17 0 0.070
myopathy DOID:423 0 0.070
cardiomyopathy DOID:0050700 0 0.070
disease of mental health DOID:150 0 0.024
developmental disorder of mental health DOID:0060037 0 0.024
disease of cellular proliferation DOID:14566 0 0.012
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.012
connective tissue disease DOID:65 0 0.011