Danio rerio

9 known processes

tlr3

toll-like receptor 3

(Aliases: MGC123006,zgc:123006)

tlr3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to lipopolysaccharide GO:0071222 3 0.937
response to other organism GO:0051707 97 0.689
defense response to bacterium GO:0042742 22 0.670
Worm Fly
response to external stimulus GO:0009605 264 0.639
neuron development GO:0048666 262 0.587
Fly
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.577
Mouse
immune system process GO:0002376 241 0.574
Human Mouse Fly
immune response regulating signaling pathway GO:0002764 5 0.563
Human
positive regulation of cytokine production GO:0001819 2 0.538
Human Mouse
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.524
Human Mouse
positive regulation of stress activated mapk cascade GO:0032874 3 0.519
Mouse
regulation of production of molecular mediator of immune response GO:0002700 1 0.515
Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.471
Mouse Fly
activation of immune response GO:0002253 9 0.464
Human
leukocyte proliferation GO:0070661 1 0.463
cellular response to molecule of bacterial origin GO:0071219 3 0.446
cellular response to biotic stimulus GO:0071216 3 0.446
regulation of cytokine production GO:0001817 3 0.440
Human Mouse
response to biotic stimulus GO:0009607 97 0.437
regulation of biosynthetic process GO:0009889 250 0.428
Human Mouse Fly
positive regulation of cell activation GO:0050867 1 0.423
regulation of protein transport GO:0051223 3 0.402
Human
i kappab kinase nf kappab signaling GO:0007249 4 0.390
Human Mouse
defense response GO:0006952 47 0.368
Mouse Worm Fly
positive regulation of jnk cascade GO:0046330 3 0.364
Mouse
hematopoietic or lymphoid organ development GO:0048534 191 0.361
cellular protein metabolic process GO:0044267 129 0.345
Human Fly
protein secretion GO:0009306 1 0.344
immune response activating signal transduction GO:0002757 5 0.338
Human
regulation of metabolic process GO:0019222 359 0.327
Human Mouse Fly
cellular macromolecule metabolic process GO:0044260 391 0.312
Human Mouse Fly
defense response to other organism GO:0098542 33 0.309
Mouse Worm Fly
response to bacterium GO:0009617 58 0.303
negative regulation of biological process GO:0048519 304 0.301
regulation of nitrogen compound metabolic process GO:0051171 251 0.295
Mouse Fly
single organism metabolic process GO:0044710 217 0.294
Mouse Fly
regulation of establishment of protein localization GO:0070201 4 0.293
Human
cellular macromolecule biosynthetic process GO:0034645 224 0.291
Mouse Fly
regulation of immune response GO:0050776 14 0.289
Human Fly
nitrogen compound metabolic process GO:0006807 319 0.284
Mouse Fly
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.276
immune system development GO:0002520 191 0.262
myeloid cell differentiation GO:0030099 86 0.261
aromatic compound biosynthetic process GO:0019438 217 0.257
Mouse
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.248
Human Mouse
regulation of cellular metabolic process GO:0031323 320 0.247
Human Mouse Fly
phosphate containing compound metabolic process GO:0006796 108 0.245
Human Mouse
organonitrogen compound metabolic process GO:1901564 74 0.239
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.233
Mouse Fly
hemopoiesis GO:0030097 183 0.233
response to external biotic stimulus GO:0043207 97 0.231
regulation of cell differentiation GO:0045595 142 0.226
Fly
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.225
response to dsrna GO:0043331 7 0.225
Human Mouse
positive regulation of catalytic activity GO:0043085 25 0.222
regulation of nucleic acid templated transcription GO:1903506 213 0.222
Mouse
mononuclear cell proliferation GO:0032943 1 0.221
central nervous system development GO:0007417 387 0.217
regulation of cellular protein metabolic process GO:0032268 52 0.213
Fly
protein metabolic process GO:0019538 183 0.211
Human Mouse Fly
regulation of primary metabolic process GO:0080090 311 0.210
Human Mouse Fly
regulation of cellular biosynthetic process GO:0031326 245 0.207
Human Mouse Fly
multi organism process GO:0051704 134 0.205
aging GO:0007568 2 0.203
organic cyclic compound metabolic process GO:1901360 301 0.203
Mouse
transport GO:0006810 220 0.198
Human
regulation of macromolecule biosynthetic process GO:0010556 225 0.193
Human Mouse Fly
gene expression GO:0010467 252 0.190
Mouse
nucleocytoplasmic transport GO:0006913 4 0.188
Human
cellular response to lipid GO:0071396 39 0.187
positive regulation of cellular process GO:0048522 201 0.186
Human Mouse Fly
regulation of gene expression GO:0010468 265 0.183
Mouse
organic substance biosynthetic process GO:1901576 289 0.182
Human Mouse Fly
response to wounding GO:0009611 116 0.180
nucleobase containing compound metabolic process GO:0006139 274 0.179
Mouse
biosynthetic process GO:0009058 294 0.177
Human Mouse Fly
cellular component movement GO:0006928 335 0.177
multicellular organismal homeostasis GO:0048871 29 0.175
regulation of binding GO:0051098 3 0.173
neuron projection development GO:0031175 180 0.172
regulation of cellular amine metabolic process GO:0033238 0 0.170
positive regulation of immune effector process GO:0002699 3 0.167
Fly
protein modification process GO:0036211 100 0.166
Human Fly
intracellular signal transduction GO:0035556 85 0.165
Human Mouse
response to chemical GO:0042221 320 0.165
Human Mouse Fly
cell projection organization GO:0030030 284 0.164
regulation of response to stimulus GO:0048583 269 0.164
Human Mouse Fly
reactive nitrogen species metabolic process GO:2001057 0 0.162
neuron differentiation GO:0030182 353 0.160
Fly
regulation of localization GO:0032879 104 0.155
Human
extrinsic apoptotic signaling pathway GO:0097191 3 0.154
Human
positive regulation of molecular function GO:0044093 33 0.152
Mouse
regulation of transcription dna templated GO:0006355 213 0.151
Mouse
nitric oxide biosynthetic process GO:0006809 2 0.150
response to organic substance GO:0010033 153 0.150
Human Mouse
cellular amino acid metabolic process GO:0006520 7 0.148
leukocyte differentiation GO:0002521 25 0.146
response to nutrient GO:0007584 3 0.145
signal transduction GO:0007165 455 0.145
Human Mouse
positive regulation of cellular metabolic process GO:0031325 94 0.145
Human Mouse Fly
regulation of macromolecule metabolic process GO:0060255 317 0.142
Human Mouse Fly
regulation of multicellular organismal development GO:2000026 223 0.141
regulation of biological quality GO:0065008 263 0.141
regulation of protein localization to nucleus GO:1900180 2 0.139
Human
rna biosynthetic process GO:0032774 181 0.138
Mouse
phosphorylation GO:0016310 69 0.135
Human Mouse
response to molecule of bacterial origin GO:0002237 14 0.135
protein import GO:0017038 3 0.134
Human
cellular biosynthetic process GO:0044249 286 0.133
Human Mouse Fly
small molecule metabolic process GO:0044281 77 0.133
generation of neurons GO:0048699 385 0.131
Fly
cellular response to organic substance GO:0071310 105 0.130
response to lipopolysaccharide GO:0032496 13 0.129
regulation of reactive oxygen species metabolic process GO:2000377 2 0.129
regulation of sequence specific dna binding transcription factor activity GO:0051090 9 0.128
Mouse
positive regulation of interferon beta production GO:0032728 1 0.127
Human Mouse
transcription dna templated GO:0006351 181 0.126
Mouse
regulation of protein targeting GO:1903533 2 0.125
Human
nucleobase containing compound biosynthetic process GO:0034654 205 0.122
Mouse
reactive oxygen species metabolic process GO:0072593 6 0.121
amine metabolic process GO:0009308 2 0.121
regulation of protein import into nucleus GO:0042306 2 0.119
Human
phosphorus metabolic process GO:0006793 109 0.119
Human Mouse
regulation of developmental process GO:0050793 247 0.118
Fly
regulation of cell activation GO:0050865 1 0.117
response to abiotic stimulus GO:0009628 122 0.114
Human
negative regulation of gene expression GO:0010629 65 0.112
morphogenesis of an epithelium GO:0002009 333 0.111
oxoacid metabolic process GO:0043436 31 0.110
regulation of phosphorus metabolic process GO:0051174 43 0.110
Mouse
cellular amine metabolic process GO:0044106 2 0.110
larval development GO:0002164 2 0.110
Worm
cellular response to chemical stimulus GO:0070887 157 0.109
response to glucocorticoid GO:0051384 1 0.108
regulation of signaling GO:0023051 235 0.107
Human Mouse
cellular localization GO:0051641 97 0.107
Human
carboxylic acid metabolic process GO:0019752 22 0.106
nucleic acid metabolic process GO:0090304 244 0.106
Mouse
response to drug GO:0042493 3 0.105
cell part morphogenesis GO:0032990 246 0.105
reactive oxygen species biosynthetic process GO:1903409 1 0.105
regulation of signal transduction GO:0009966 225 0.105
Human Mouse
regulation of protein metabolic process GO:0051246 56 0.104
Human Mouse Fly
positive regulation of metabolic process GO:0009893 108 0.104
Human Mouse Fly
positive regulation of leukocyte mediated immunity GO:0002705 1 0.103
regulation of leukocyte mediated immunity GO:0002703 1 0.102
neuron projection morphogenesis GO:0048812 161 0.102
organic cyclic compound biosynthetic process GO:1901362 223 0.102
Mouse
innate immune response GO:0045087 13 0.102
Fly
positive regulation of response to external stimulus GO:0032103 9 0.101
Fly
response to organic cyclic compound GO:0014070 51 0.101
Human Mouse
multicellular organismal metabolic process GO:0044236 2 0.100
cell projection morphogenesis GO:0048858 244 0.100
cell morphogenesis involved in differentiation GO:0000904 195 0.100
lymphocyte proliferation GO:0046651 1 0.099
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.097
Mouse
regulation of immune system process GO:0002682 34 0.097
Human Fly
peptide transport GO:0015833 1 0.097
Human
positive regulation of map kinase activity GO:0043406 3 0.095
negative regulation of cellular process GO:0048523 283 0.094
axon development GO:0061564 166 0.094
positive regulation of biological process GO:0048518 253 0.093
Human Mouse Fly
cytokine mediated signaling pathway GO:0019221 7 0.092
homeostatic process GO:0042592 142 0.092
cell proliferation GO:0008283 80 0.091
Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.090
Mouse Fly
tissue homeostasis GO:0001894 25 0.090
cellular response to nutrient levels GO:0031669 2 0.090
protein targeting to nucleus GO:0044744 3 0.090
Human
regulation of cellular amino acid metabolic process GO:0006521 0 0.090
macromolecule modification GO:0043412 111 0.089
Human Fly
cell surface receptor signaling pathway GO:0007166 325 0.088
Human
regulation of cell communication GO:0010646 232 0.088
Human Mouse
cellular ketone metabolic process GO:0042180 11 0.088
ossification GO:0001503 23 0.087
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.086
Mouse
response to transition metal nanoparticle GO:1990267 28 0.086
protein localization to nucleus GO:0034504 3 0.086
Human
embryonic organ development GO:0048568 381 0.085
cellular component biogenesis GO:0044085 178 0.085
Fly
negative regulation of metabolic process GO:0009892 86 0.085
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 1 0.084
cellular protein modification process GO:0006464 100 0.084
Human Fly
positive regulation of cellular catabolic process GO:0031331 3 0.084
negative regulation of protein phosphorylation GO:0001933 4 0.083
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.083
protein phosphorylation GO:0006468 47 0.083
Human
cellular nitrogen compound biosynthetic process GO:0044271 218 0.083
Mouse Fly
nuclear transport GO:0051169 4 0.082
Human
establishment of localization GO:0051234 244 0.082
Human
liver development GO:0001889 96 0.081
single organism nuclear import GO:1902593 3 0.081
Human
nik nf kappab signaling GO:0038061 1 0.081
anatomical structure homeostasis GO:0060249 36 0.081
regulation of molecular function GO:0065009 70 0.079
Mouse
retina development in camera type eye GO:0060041 146 0.079
macromolecule biosynthetic process GO:0009059 227 0.079
Human Mouse Fly
erythrocyte homeostasis GO:0034101 55 0.077
axonogenesis GO:0007409 152 0.076
osteoclast differentiation GO:0030316 1 0.076
negative regulation of protein transport GO:0051224 3 0.076
rna metabolic process GO:0016070 219 0.075
Mouse
positive regulation of cell communication GO:0010647 56 0.075
Human Mouse
production of molecular mediator of immune response GO:0002440 2 0.074
Fly
positive regulation of immune system process GO:0002684 17 0.074
Human Fly
epithelial tube morphogenesis GO:0060562 148 0.074
alpha amino acid metabolic process GO:1901605 3 0.073
response to stress GO:0006950 263 0.073
Mouse Worm Fly
response to oxygen containing compound GO:1901700 55 0.073
localization of cell GO:0051674 244 0.071
single organism transport GO:0044765 206 0.071
Human
response to virus GO:0009615 21 0.071
chordate embryonic development GO:0043009 271 0.070
tissue remodeling GO:0048771 4 0.070
negative regulation of signal transduction GO:0009968 94 0.070
growth GO:0040007 174 0.070
regulation of rna biosynthetic process GO:2001141 213 0.070
Mouse
regulation of phosphate metabolic process GO:0019220 43 0.070
Mouse
protein localization GO:0008104 40 0.069
Human
cell migration GO:0016477 237 0.069
response to alkaloid GO:0043279 2 0.069
regulation of cell proliferation GO:0042127 37 0.068
regulation of nucleocytoplasmic transport GO:0046822 2 0.068
Human
cellular aromatic compound metabolic process GO:0006725 295 0.068
Mouse
heterocycle biosynthetic process GO:0018130 215 0.068
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.067
Human Mouse
nitric oxide metabolic process GO:0046209 2 0.066
anion transport GO:0006820 38 0.066
cell morphogenesis GO:0000902 289 0.065
response to exogenous dsrna GO:0043330 6 0.065
Human Mouse
sensory perception of pain GO:0019233 1 0.065
negative regulation of macromolecule metabolic process GO:0010605 76 0.064
positive regulation of myeloid cell differentiation GO:0045639 2 0.064
cellular response to extracellular stimulus GO:0031668 2 0.064
response to lipid GO:0033993 60 0.064
vasculature development GO:0001944 278 0.063
response to decreased oxygen levels GO:0036293 25 0.063
establishment of protein localization to organelle GO:0072594 4 0.063
Human
response to metal ion GO:0010038 34 0.062
response to ketone GO:1901654 1 0.061
eye development GO:0001654 277 0.061
cellular carbohydrate metabolic process GO:0044262 4 0.061
Fly
small molecule catabolic process GO:0044282 3 0.061
amino acid transport GO:0006865 2 0.060
immunoglobulin mediated immune response GO:0016064 3 0.060
angiogenesis GO:0001525 158 0.060
negative regulation of cytokine production GO:0001818 1 0.060
regulation of phosphorylation GO:0042325 26 0.060
Mouse
positive regulation of transport GO:0051050 2 0.060
Human
erythrocyte differentiation GO:0030218 54 0.060
immunoglobulin production GO:0002377 1 0.059
positive regulation of rna biosynthetic process GO:1902680 57 0.059
Mouse
regulation of response to external stimulus GO:0032101 31 0.059
Fly
phagocytosis GO:0006909 3 0.058
response to endogenous stimulus GO:0009719 83 0.058
immune effector process GO:0002252 23 0.058
Mouse Fly
secondary metabolic process GO:0019748 3 0.058
regulation of cell cycle GO:0051726 52 0.058
negative regulation of cell communication GO:0010648 96 0.057
macromolecule localization GO:0033036 54 0.057
Human
locomotion GO:0040011 313 0.056
Fly
positive regulation of gene expression GO:0010628 71 0.056
Mouse
protein polyubiquitination GO:0000209 4 0.055
gtp metabolic process GO:0046039 4 0.055
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.054
sensory organ development GO:0007423 393 0.054
regulation of intracellular protein transport GO:0033157 3 0.054
Human
nuclear import GO:0051170 3 0.054
Human
ion homeostasis GO:0050801 41 0.053
signal transduction by phosphorylation GO:0023014 18 0.053
Mouse
sensory organ morphogenesis GO:0090596 200 0.053
cell motility GO:0048870 244 0.052
metal ion homeostasis GO:0055065 26 0.052
positive regulation of cellular biosynthetic process GO:0031328 68 0.052
Human Mouse Fly
organic acid catabolic process GO:0016054 3 0.052
guanosine containing compound metabolic process GO:1901068 4 0.052
regulation of rna metabolic process GO:0051252 224 0.051
Mouse
cellular response to external stimulus GO:0071496 2 0.051
Human
regulation of mapk cascade GO:0043408 14 0.051
Mouse
blood vessel development GO:0001568 246 0.051
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.049
organic acid metabolic process GO:0006082 31 0.049
positive regulation of cellular amine metabolic process GO:0033240 0 0.049
negative regulation of kinase activity GO:0033673 4 0.048
positive regulation of cell cycle GO:0045787 3 0.048
regulation of transferase activity GO:0051338 16 0.048
brain development GO:0007420 293 0.047
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.047
positive regulation of response to stimulus GO:0048584 80 0.047
Human Mouse Fly
response to acid chemical GO:0001101 17 0.047
regulation of cytoplasmic transport GO:1903649 4 0.047
Human
tyrosine phosphorylation of stat protein GO:0007260 1 0.047
regulation of response to stress GO:0080134 36 0.046
Human Mouse Fly
regulation of protein phosphorylation GO:0001932 18 0.046
positive regulation of neuron apoptotic process GO:0043525 1 0.046
single organism cellular localization GO:1902580 46 0.046
Human
establishment of localization in cell GO:0051649 77 0.046
Human
hindbrain development GO:0030902 91 0.045
iron ion homeostasis GO:0055072 4 0.045
protein complex localization GO:0031503 1 0.045
Human
regulation of nervous system development GO:0051960 90 0.045
developmental growth involved in morphogenesis GO:0060560 86 0.045
positive regulation of jak stat cascade GO:0046427 2 0.045
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.044
adaptive immune response GO:0002250 5 0.044
developmental growth GO:0048589 166 0.044
muscle organ development GO:0007517 101 0.044
chemotaxis GO:0006935 104 0.043
Fly
lymphocyte mediated immunity GO:0002449 5 0.043
regulation of cellular ketone metabolic process GO:0010565 7 0.043
defense response to gram negative bacterium GO:0050829 8 0.043
Worm
response to arsenic containing substance GO:0046685 5 0.043
positive regulation of signal transduction GO:0009967 56 0.042
Human Mouse
tube morphogenesis GO:0035239 349 0.042
hepaticobiliary system development GO:0061008 98 0.042
negative regulation of protein kinase activity GO:0006469 4 0.042
response to monosaccharide GO:0034284 3 0.041
anterior posterior pattern specification GO:0009952 152 0.041
intracellular transport GO:0046907 32 0.041
Human
negative regulation of intracellular signal transduction GO:1902532 22 0.041
regulation of metal ion transport GO:0010959 4 0.041
regulation of multicellular organismal process GO:0051239 277 0.041
Human Mouse Fly
positive regulation of gtp catabolic process GO:0033126 1 0.040
head development GO:0060322 303 0.040
carbohydrate derivative biosynthetic process GO:1901137 43 0.040
Fly
chemical homeostasis GO:0048878 49 0.040
regulation of translation GO:0006417 3 0.040
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.040
cellular response to starvation GO:0009267 1 0.039
system process GO:0003008 185 0.039
multicellular organism growth GO:0035264 4 0.038
embryonic hemopoiesis GO:0035162 53 0.038
leukocyte activation GO:0045321 12 0.038
positive regulation of macromolecule metabolic process GO:0010604 93 0.038
Human Mouse
positive regulation of secretion GO:0051047 1 0.038
positive regulation of gliogenesis GO:0014015 2 0.037
guanosine containing compound catabolic process GO:1901069 2 0.037
regulation of myeloid cell differentiation GO:0045637 8 0.037
positive regulation of cell death GO:0010942 29 0.037
regulation of cellular component organization GO:0051128 86 0.036
nucleic acid templated transcription GO:0097659 181 0.036
Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.036
positive regulation of catabolic process GO:0009896 4 0.036
somatic muscle development GO:0007525 4 0.035
negative regulation of response to stimulus GO:0048585 104 0.035
carboxylic acid catabolic process GO:0046395 3 0.035
astrocyte differentiation GO:0048708 1 0.035
positive regulation of rna metabolic process GO:0051254 59 0.035
Mouse
regulation of kinase activity GO:0043549 15 0.034
maintenance of location GO:0051235 4 0.034
cellular component morphogenesis GO:0032989 336 0.034
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.034
regulation of jak stat cascade GO:0046425 3 0.034
b cell activation GO:0042113 2 0.034
response to glucose GO:0009749 3 0.034
negative regulation of signaling GO:0023057 96 0.034
positive regulation of inflammatory response GO:0050729 1 0.034
mitochondrion organization GO:0007005 4 0.033
negative regulation of hormone secretion GO:0046888 2 0.033
immune response GO:0006955 28 0.033
Fly
b cell mediated immunity GO:0019724 3 0.033
regulation of catalytic activity GO:0050790 55 0.033
cellular component assembly GO:0022607 170 0.033
Fly
positive regulation of cell proliferation GO:0008284 15 0.032
cell fate commitment GO:0045165 99 0.032
regulation of transport GO:0051049 45 0.032
Human
multicellular organismal macromolecule metabolic process GO:0044259 2 0.032
regulation of neuron differentiation GO:0045664 56 0.032
regulation of tyrosine phosphorylation of stat3 protein GO:0042516 1 0.032
regulation of cell death GO:0010941 103 0.032
negative regulation of phosphate metabolic process GO:0045936 13 0.032
response to corticosteroid GO:0031960 1 0.032
myeloid leukocyte differentiation GO:0002573 15 0.031
translational initiation GO:0006413 3 0.031
dicarboxylic acid transport GO:0006835 1 0.031
gland development GO:0048732 143 0.031
response to amino acid GO:0043200 2 0.031
regulation of anatomical structure morphogenesis GO:0022603 130 0.031
cellular response to stress GO:0033554 62 0.031
Mouse
regulation of calcium ion transport GO:0051924 2 0.031
heterocycle metabolic process GO:0046483 290 0.030
Mouse
phagocytosis engulfment GO:0006911 1 0.030
homeostasis of number of cells GO:0048872 62 0.030
negative regulation of cellular metabolic process GO:0031324 77 0.030
single organism localization GO:1902578 225 0.029
Human
neural retina development GO:0003407 49 0.029
regulation of purine nucleotide catabolic process GO:0033121 2 0.029
regulation of immune effector process GO:0002697 5 0.029
Fly
lipid storage GO:0019915 1 0.029
regulation of cellular component movement GO:0051270 55 0.029
regulation of circadian rhythm GO:0042752 4 0.029
death GO:0016265 121 0.029
Human
response to hypoxia GO:0001666 25 0.029
response to nitrogen compound GO:1901698 19 0.028
Human Mouse
enzyme linked receptor protein signaling pathway GO:0007167 106 0.028
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.028
positive regulation of epithelial cell proliferation GO:0050679 1 0.028
carbohydrate metabolic process GO:0005975 12 0.028
Fly
multi organism cellular process GO:0044764 2 0.028
spinal cord development GO:0021510 46 0.028
regulation of nucleotide catabolic process GO:0030811 2 0.027
protein import into nucleus GO:0006606 3 0.027
Human
regulation of protein ubiquitination GO:0031396 3 0.027
striated muscle cell differentiation GO:0051146 129 0.026
organelle organization GO:0006996 227 0.026
myeloid cell homeostasis GO:0002262 56 0.026
regulation of cell growth GO:0001558 29 0.026
single organism biosynthetic process GO:0044711 71 0.026
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.026
t cell activation GO:0042110 6 0.026
regulation of cell motility GO:2000145 46 0.026
positive regulation of developmental process GO:0051094 50 0.026
carbohydrate derivative metabolic process GO:1901135 61 0.026
Fly
eye morphogenesis GO:0048592 144 0.026
positive regulation of phosphorus metabolic process GO:0010562 21 0.025
Mouse
positive regulation of secretion by cell GO:1903532 1 0.025
regulation of inflammatory response GO:0050727 2 0.025
response to cytokine GO:0034097 7 0.025
cellular response to cytokine stimulus GO:0071345 7 0.025
cellular response to endogenous stimulus GO:0071495 68 0.025
erk1 and erk2 cascade GO:0070371 4 0.025
response to hormone GO:0009725 48 0.025
hormone transport GO:0009914 2 0.025
developmental cell growth GO:0048588 52 0.025
negative regulation of rna metabolic process GO:0051253 48 0.024
energy reserve metabolic process GO:0006112 2 0.024
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.024
negative regulation of cellular biosynthetic process GO:0031327 55 0.024
regulation of neurogenesis GO:0050767 87 0.024
gtp catabolic process GO:0006184 2 0.024
convergent extension GO:0060026 118 0.024
melanin metabolic process GO:0006582 2 0.024
leukocyte mediated immunity GO:0002443 6 0.024
calcium mediated signaling GO:0019722 2 0.024
negative regulation of mapk cascade GO:0043409 4 0.024
regulation of collagen metabolic process GO:0010712 2 0.024
regulation of circadian sleep wake cycle GO:0042749 1 0.024
collagen metabolic process GO:0032963 2 0.024
regulation of cellular response to stress GO:0080135 20 0.024
Mouse
regulation of multicellular organism growth GO:0040014 4 0.024
response to uv GO:0009411 3 0.024
regulation of lymphocyte mediated immunity GO:0002706 1 0.024
retina morphogenesis in camera type eye GO:0060042 79 0.024
negative regulation of biosynthetic process GO:0009890 55 0.023
fatty acid biosynthetic process GO:0006633 4 0.023
regulation of blood vessel size GO:0050880 2 0.023
camera type eye development GO:0043010 222 0.023
regulation of response to cytokine stimulus GO:0060759 3 0.023
negative regulation of cell differentiation GO:0045596 46 0.023
regulation of protein kinase activity GO:0045859 15 0.023
humoral immune response mediated by circulating immunoglobulin GO:0002455 3 0.023
pyruvate metabolic process GO:0006090 1 0.023
determination of left right symmetry GO:0007368 179 0.023
positive regulation of apoptotic signaling pathway GO:2001235 1 0.023
long chain fatty acid metabolic process GO:0001676 1 0.023
regulation of hormone secretion GO:0046883 2 0.023
regulation of programmed cell death GO:0043067 101 0.023
interspecies interaction between organisms GO:0044419 4 0.023
stem cell proliferation GO:0072089 4 0.023
cellular response to oxygen containing compound GO:1901701 20 0.023
transcription from rna polymerase ii promoter GO:0006366 80 0.022
Mouse
cell growth GO:0016049 57 0.022
negative regulation of secretion GO:0051048 2 0.022
regulation of multicellular organismal metabolic process GO:0044246 2 0.022
negative regulation of rna biosynthetic process GO:1902679 45 0.022
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.022
regulation of apoptotic process GO:0042981 98 0.022
negative regulation of secretion by cell GO:1903531 2 0.022
positive regulation of tyrosine phosphorylation of stat protein GO:0042531 1 0.022
cellular response to hypoxia GO:0071456 1 0.022
membrane invagination GO:0010324 1 0.021
lipid metabolic process GO:0006629 52 0.021
neuron death GO:0070997 21 0.021
cellular transition metal ion homeostasis GO:0046916 3 0.021
response to carbohydrate GO:0009743 3 0.021
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.021
positive regulation of leukocyte differentiation GO:1902107 1 0.021
regulation of intracellular signal transduction GO:1902531 57 0.021
Human Mouse
regulation of cell development GO:0060284 100 0.021
positive regulation of biosynthetic process GO:0009891 68 0.021
Human Mouse Fly
blood vessel morphogenesis GO:0048514 216 0.021
regulation of glucose transport GO:0010827 1 0.020
glucose homeostasis GO:0042593 1 0.020
regulation of response to nutrient levels GO:0032107 1 0.020
regulation of nucleoside metabolic process GO:0009118 2 0.020
protein kinase b signaling GO:0043491 9 0.020
gliogenesis GO:0042063 45 0.020
positive regulation of protein kinase b signaling GO:0051897 1 0.020
myotube differentiation GO:0014902 45 0.020
response to hexose GO:0009746 3 0.020
positive regulation of multi organism process GO:0043902 3 0.020
Fly
regulation of system process GO:0044057 40 0.020
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.020
negative regulation of multicellular organismal process GO:0051241 69 0.020

tlr3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
organ system cancer DOID:0050686 0 0.036
cancer DOID:162 0 0.036
disease of cellular proliferation DOID:14566 0 0.036
disease of metabolism DOID:0014667 0 0.025
disease of anatomical entity DOID:7 0 0.024