Danio rerio

49 known processes

tmie

transmembrane inner ear

(Aliases: si:ch211-163f10.1)

tmie biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory organ development GO:0007423 393 0.948
generation of neurons GO:0048699 385 0.584
hair cell differentiation GO:0035315 32 0.525
neuromast development GO:0048884 46 0.441
regulation of biological quality GO:0065008 263 0.332
sensory organ morphogenesis GO:0090596 200 0.307
ear development GO:0043583 127 0.306
pigmentation GO:0043473 85 0.270
response to chemical GO:0042221 320 0.239
sensory system development GO:0048880 76 0.217
inner ear receptor stereocilium organization GO:0060122 8 0.204
lateral line system development GO:0048925 76 0.201
transmembrane transport GO:0055085 120 0.194
detection of mechanical stimulus involved in sensory perception GO:0050974 11 0.187
lateral line development GO:0048882 66 0.186
monoamine transport GO:0015844 1 0.176
single organism localization GO:1902578 225 0.169
inner ear development GO:0048839 126 0.155
eye development GO:0001654 277 0.139
epidermal cell differentiation GO:0009913 36 0.137
mechanoreceptor differentiation GO:0042490 37 0.120
reflex GO:0060004 2 0.120
adult behavior GO:0030534 2 0.119
myelination of lateral line nerve axons GO:0048897 5 0.118
pigment granule localization GO:0051875 25 0.117
eye morphogenesis GO:0048592 144 0.113
cilium organization GO:0044782 71 0.106
microtubule based movement GO:0007018 33 0.098
sensory perception of mechanical stimulus GO:0050954 16 0.089
signal transduction GO:0007165 455 0.080
epithelial cell differentiation GO:0030855 116 0.077
retina development in camera type eye GO:0060041 146 0.077
neuron differentiation GO:0030182 353 0.077
post embryonic organ development GO:0048569 4 0.074
nitrogen compound metabolic process GO:0006807 319 0.073
homeostasis of number of cells GO:0048872 62 0.072
localization of cell GO:0051674 244 0.071
myelination of anterior lateral line nerve axons GO:0048914 3 0.070
epidermis development GO:0008544 48 0.070
anion transmembrane transport GO:0098656 12 0.065
liver development GO:0001889 96 0.065
neurological system process GO:0050877 62 0.064
neuron neuron synaptic transmission GO:0007270 1 0.064
pigment cell differentiation GO:0050931 38 0.062
inner ear morphogenesis GO:0042472 63 0.061
response to drug GO:0042493 3 0.060
synaptic vesicle recycling GO:0036465 1 0.060
larval development GO:0002164 2 0.059
photoreceptor cell outer segment organization GO:0035845 9 0.059
regionalization GO:0003002 274 0.057
transport GO:0006810 220 0.057
gland development GO:0048732 143 0.056
negative regulation of response to stimulus GO:0048585 104 0.056
embryonic organ morphogenesis GO:0048562 274 0.055
ion transmembrane transport GO:0034220 91 0.055
response to xenobiotic stimulus GO:0009410 45 0.054
camera type eye morphogenesis GO:0048593 108 0.054
single organism transport GO:0044765 206 0.054
neurotransmitter transport GO:0006836 2 0.054
regulation of signaling GO:0023051 235 0.052
system process GO:0003008 185 0.051
cell morphogenesis GO:0000902 289 0.050
inner ear receptor cell development GO:0060119 20 0.050
establishment of localization GO:0051234 244 0.048
tissue regeneration GO:0042246 74 0.048
morphogenesis of an epithelium GO:0002009 333 0.047
hepaticobiliary system development GO:0061008 98 0.047
cation transmembrane transport GO:0098655 65 0.046
regulation of blood pressure GO:0008217 1 0.045
cell surface receptor signaling pathway GO:0007166 325 0.045
neuron development GO:0048666 262 0.044
action potential GO:0001508 19 0.044
developmental pigmentation GO:0048066 48 0.044
negative regulation of biological process GO:0048519 304 0.044
cell projection organization GO:0030030 284 0.043
inner ear receptor cell differentiation GO:0060113 29 0.043
inorganic ion transmembrane transport GO:0098660 57 0.041
programmed cell death GO:0012501 119 0.040
positive regulation of secretion GO:0051047 1 0.040
phagocytosis GO:0006909 3 0.040
skin development GO:0043588 54 0.039
regulation of multicellular organismal development GO:2000026 223 0.039
wound healing GO:0042060 90 0.039
regulation of developmental process GO:0050793 247 0.039
digestive tract development GO:0048565 265 0.038
cell projection morphogenesis GO:0048858 244 0.038
positive regulation of biological process GO:0048518 253 0.037
regulation of membrane repolarization GO:0060306 1 0.037
startle response GO:0001964 4 0.036
peripheral nervous system development GO:0007422 55 0.036
fin development GO:0033333 77 0.036
regulation of cell communication GO:0010646 232 0.036
post embryonic organ morphogenesis GO:0048563 1 0.036
auditory receptor cell differentiation GO:0042491 15 0.035
developmental programmed cell death GO:0010623 4 0.035
microtubule based process GO:0007017 60 0.034
regulation of response to stimulus GO:0048583 269 0.034
multicellular organismal signaling GO:0035637 22 0.034
cell part morphogenesis GO:0032990 246 0.034
positive regulation of response to stimulus GO:0048584 80 0.033
cilium morphogenesis GO:0060271 85 0.033
hematopoietic or lymphoid organ development GO:0048534 191 0.033
regulation of binding GO:0051098 3 0.033
positive regulation of catabolic process GO:0009896 4 0.033
erythrocyte homeostasis GO:0034101 55 0.033
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.033
retina morphogenesis in camera type eye GO:0060042 79 0.032
amine metabolic process GO:0009308 2 0.032
cellular component assembly involved in morphogenesis GO:0010927 107 0.032
immune system development GO:0002520 191 0.032
membrane hyperpolarization GO:0060081 1 0.032
exocytosis GO:0006887 1 0.032
response to stress GO:0006950 263 0.032
cellular response to chemical stimulus GO:0070887 157 0.031
regeneration GO:0031099 91 0.031
heterocycle metabolic process GO:0046483 290 0.031
regulation of protein binding GO:0043393 3 0.031
small molecule metabolic process GO:0044281 77 0.031
transmission of nerve impulse GO:0019226 19 0.031
death GO:0016265 121 0.031
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.031
detection of mechanical stimulus GO:0050982 11 0.031
cognition GO:0050890 1 0.031
medial fin development GO:0033338 16 0.030
embryonic hemopoiesis GO:0035162 53 0.030
positive regulation of wound healing GO:0090303 1 0.030
circulatory system process GO:0003013 87 0.030
extrinsic apoptotic signaling pathway GO:0097191 3 0.030
positive regulation of cell communication GO:0010647 56 0.029
regulation of apoptotic process GO:0042981 98 0.029
organelle organization GO:0006996 227 0.029
cellular aromatic compound metabolic process GO:0006725 295 0.029
ion transport GO:0006811 114 0.029
cellular component biogenesis GO:0044085 178 0.028
nonmotile primary cilium assembly GO:0035058 2 0.028
guanosine containing compound catabolic process GO:1901069 2 0.028
regulation of synaptic plasticity GO:0048167 1 0.028
cell projection assembly GO:0030031 64 0.028
positive regulation of nucleoside metabolic process GO:0045979 1 0.028
cilium assembly GO:0042384 58 0.027
multicellular organism growth GO:0035264 4 0.027
regulation of multicellular organismal process GO:0051239 277 0.027
morphogenesis of follicular epithelium GO:0016333 1 0.027
phosphate containing compound metabolic process GO:0006796 108 0.027
growth GO:0040007 174 0.027
regulation of protein catabolic process GO:0042176 1 0.026
eye photoreceptor cell differentiation GO:0001754 45 0.026
cellular component morphogenesis GO:0032989 336 0.026
cell death GO:0008219 121 0.026
oxoacid metabolic process GO:0043436 31 0.026
behavior GO:0007610 74 0.026
brain development GO:0007420 293 0.026
auditory receptor cell morphogenesis GO:0002093 4 0.026
determination of bilateral symmetry GO:0009855 204 0.025
positive regulation of cellular amine metabolic process GO:0033240 0 0.025
appendage development GO:0048736 80 0.025
cilium movement GO:0003341 26 0.025
regulation of membrane potential GO:0042391 23 0.025
positive regulation of transport GO:0051050 2 0.025
erythrocyte differentiation GO:0030218 54 0.025
dorsal ventral pattern formation GO:0009953 125 0.025
regulation of retina development in camera type eye GO:1902866 2 0.025
nucleoside monophosphate catabolic process GO:0009125 4 0.025
positive regulation of gtp catabolic process GO:0033126 1 0.024
axoneme assembly GO:0035082 9 0.024
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.024
cellular amine metabolic process GO:0044106 2 0.024
positive regulation of ras protein signal transduction GO:0046579 1 0.024
appendage morphogenesis GO:0035107 56 0.024
homeostatic process GO:0042592 142 0.024
regulation of ion transmembrane transporter activity GO:0032412 2 0.024
neuromuscular process GO:0050905 7 0.024
response to external stimulus GO:0009605 264 0.023
regulation of localization GO:0032879 104 0.023
cellular protein modification process GO:0006464 100 0.023
kidney development GO:0001822 92 0.023
camera type eye development GO:0043010 222 0.023
positive regulation of cell adhesion GO:0045785 1 0.022
digestive system development GO:0055123 289 0.022
modification dependent protein catabolic process GO:0019941 3 0.022
somatic muscle development GO:0007525 4 0.022
autophagy GO:0006914 4 0.022
regulation of establishment of protein localization GO:0070201 4 0.022
regulation of macromolecule metabolic process GO:0060255 317 0.022
regulation of protein transport GO:0051223 3 0.022
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.022
regulation of molecular function GO:0065009 70 0.022
synaptic vesicle transport GO:0048489 1 0.022
organonitrogen compound metabolic process GO:1901564 74 0.021
anion transport GO:0006820 38 0.021
regulation of cellular amine metabolic process GO:0033238 0 0.021
membrane repolarization GO:0086009 2 0.021
apoptotic process involved in development GO:1902742 2 0.021
synaptic vesicle endocytosis GO:0048488 1 0.021
protein metabolic process GO:0019538 183 0.021
regulation of cell death GO:0010941 103 0.020
negative regulation of programmed cell death GO:0043069 58 0.020
establishment of synaptic vesicle localization GO:0097480 1 0.020
apoptotic process GO:0006915 116 0.020
auditory receptor cell development GO:0060117 8 0.020
regulation of signal transduction GO:0009966 225 0.020
endocrine process GO:0050886 2 0.020
anterior lateral line nerve glial cell development GO:0048939 3 0.020
response to wounding GO:0009611 116 0.020
transcription from rna polymerase ii promoter GO:0006366 80 0.020
immune system process GO:0002376 241 0.019
synaptic transmission glycinergic GO:0060012 1 0.019
amino acid transport GO:0006865 2 0.019
hemopoiesis GO:0030097 183 0.019
retinal rod cell development GO:0046548 4 0.019
cellular macromolecule metabolic process GO:0044260 391 0.019
signal transduction in absence of ligand GO:0038034 1 0.019
cellular amino acid metabolic process GO:0006520 7 0.019
cellular response to external stimulus GO:0071496 2 0.019
alcohol biosynthetic process GO:0046165 2 0.019
organic substance transport GO:0071702 58 0.019
cellular response to nutrient levels GO:0031669 2 0.019
cellular response to organic substance GO:0071310 105 0.019
establishment of protein localization to organelle GO:0072594 4 0.019
blood vessel morphogenesis GO:0048514 216 0.019
positive regulation of epithelial cell proliferation GO:0050679 1 0.019
multi organism process GO:0051704 134 0.019
regulation of transporter activity GO:0032409 2 0.018
negative regulation of signal transduction GO:0009968 94 0.018
positive regulation of signal transduction GO:0009967 56 0.018
regulation of nucleoside metabolic process GO:0009118 2 0.018
response to abiotic stimulus GO:0009628 122 0.018
embryonic appendage morphogenesis GO:0035113 30 0.018
synaptic vesicle localization GO:0097479 1 0.018
positive regulation of nucleotide catabolic process GO:0030813 1 0.018
glucose import GO:0046323 2 0.018
cellular response to starvation GO:0009267 1 0.018
cellular component disassembly GO:0022411 1 0.018
stem cell differentiation GO:0048863 117 0.018
tube closure GO:0060606 1 0.017
centrosome cycle GO:0007098 1 0.017
organelle assembly GO:0070925 110 0.017
regulation of transmembrane transporter activity GO:0022898 2 0.017
positive regulation of map kinase activity GO:0043406 3 0.017
axon ensheathment GO:0008366 18 0.017
regulation of purine nucleotide catabolic process GO:0033121 2 0.017
neurotransmitter secretion GO:0007269 2 0.017
anterior lateral line nerve glial cell differentiation GO:0048913 3 0.017
neural crest cell differentiation GO:0014033 72 0.017
vasculature development GO:0001944 278 0.017
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.017
l amino acid transport GO:0015807 1 0.017
negative regulation of catabolic process GO:0009895 3 0.017
apoptotic process involved in morphogenesis GO:0060561 2 0.017
regulation of cell differentiation GO:0045595 142 0.017
response to topologically incorrect protein GO:0035966 2 0.017
fin regeneration GO:0031101 51 0.017
regulation of metal ion transport GO:0010959 4 0.016
mechanosensory behavior GO:0007638 2 0.016
macroautophagy GO:0016236 1 0.016
ear morphogenesis GO:0042471 64 0.016
regulation of multicellular organism growth GO:0040014 4 0.016
regulation of neuronal synaptic plasticity GO:0048168 1 0.016
myeloid cell differentiation GO:0030099 86 0.016
neuroblast proliferation GO:0007405 2 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.016
anterior lateral line nerve development GO:0048909 4 0.016
golgi vesicle transport GO:0048193 3 0.016
ribonucleoside monophosphate catabolic process GO:0009158 4 0.016
nucleic acid metabolic process GO:0090304 244 0.016
determination of left right symmetry GO:0007368 179 0.016
myelination GO:0042552 18 0.016
locomotory behavior GO:0007626 34 0.016
primary neural tube formation GO:0014020 1 0.016
sodium ion transport GO:0006814 24 0.015
regulation of glucose import GO:0046324 1 0.015
embryonic organ development GO:0048568 381 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.015
hormone secretion GO:0046879 2 0.015
positive regulation of gtpase activity GO:0043547 1 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.015
regulation of organ growth GO:0046620 3 0.015
regulation of nucleotide catabolic process GO:0030811 2 0.015
modification dependent macromolecule catabolic process GO:0043632 3 0.015
negative regulation of endopeptidase activity GO:0010951 10 0.015
anterior lateral line nerve glial cell morphogenesis involved in differentiation GO:0048940 3 0.015
ribosomal small subunit biogenesis GO:0042274 2 0.015
stem cell proliferation GO:0072089 4 0.015
melanocyte differentiation GO:0030318 26 0.015
regulation of metabolic process GO:0019222 359 0.015
tissue remodeling GO:0048771 4 0.015
germ line stem cell maintenance GO:0030718 2 0.014
positive regulation of cellular catabolic process GO:0031331 3 0.014
regulation of muscle hypertrophy GO:0014743 2 0.014
negative regulation of secretion GO:0051048 2 0.014
organism emergence from protective structure GO:0071684 4 0.014
trabecula morphogenesis GO:0061383 2 0.014
leukocyte proliferation GO:0070661 1 0.014
regulation of cellular component organization GO:0051128 86 0.014
regulation of dendrite development GO:0050773 3 0.014
compound eye development GO:0048749 2 0.014
photoreceptor cell differentiation GO:0046530 55 0.014
response to organic substance GO:0010033 153 0.014
schwann cell development GO:0014044 9 0.014
regulation of primary metabolic process GO:0080090 311 0.014
negative regulation of cell communication GO:0010648 96 0.014
head development GO:0060322 303 0.014
cellular ketone metabolic process GO:0042180 11 0.014
positive regulation of secretion by cell GO:1903532 1 0.014
metal ion transport GO:0030001 58 0.013
positive regulation of cellular component biogenesis GO:0044089 3 0.013
developmental growth GO:0048589 166 0.013
cellular response to extracellular stimulus GO:0031668 2 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.013
chloride transmembrane transport GO:1902476 4 0.013
purine nucleoside monophosphate catabolic process GO:0009128 4 0.013
locomotion GO:0040011 313 0.013
lymph vessel morphogenesis GO:0036303 25 0.013
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.013
otic vesicle development GO:0071599 42 0.013
myeloid cell homeostasis GO:0002262 56 0.013
nuclear export GO:0051168 1 0.013
proteasomal protein catabolic process GO:0010498 2 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.013
meiotic cell cycle process GO:1903046 3 0.013
melanosome localization GO:0032400 21 0.013
regulation of neuron differentiation GO:0045664 56 0.013
protein complex disassembly GO:0043241 1 0.013
neuromuscular process controlling balance GO:0050885 3 0.012
intracellular signal transduction GO:0035556 85 0.012
regulation of gtp catabolic process GO:0033124 2 0.012
golgi organization GO:0007030 1 0.012
cell motility GO:0048870 244 0.012
establishment of vesicle localization GO:0051650 24 0.012
negative regulation of reproductive process GO:2000242 3 0.012
aging GO:0007568 2 0.012
mesenchymal cell development GO:0014031 78 0.012
single organism membrane fusion GO:0044801 2 0.012
tube morphogenesis GO:0035239 349 0.012
regulation of catalytic activity GO:0050790 55 0.012
blood vessel development GO:0001568 246 0.012
skeletal system morphogenesis GO:0048705 102 0.012
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.012
cellular protein catabolic process GO:0044257 4 0.012
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.012
regulation of cellular ketone metabolic process GO:0010565 7 0.012
regulation of reproductive process GO:2000241 4 0.012
cation transport GO:0006812 81 0.012
regulation of mitotic recombination GO:0000019 2 0.011
centrosome organization GO:0051297 1 0.011
lamellipodium organization GO:0097581 1 0.011
chemosensory behavior GO:0007635 1 0.011
positive regulation of neuron death GO:1901216 1 0.011
cellular response to light stimulus GO:0071482 4 0.011
regulation of ion transmembrane transport GO:0034765 18 0.011
neuromast hair cell differentiation GO:0048886 12 0.011
single organism cellular localization GO:1902580 46 0.011
post embryonic morphogenesis GO:0009886 4 0.011
regulation of epithelial cell proliferation GO:0050678 3 0.011
cellular protein metabolic process GO:0044267 129 0.011
regulation of cell activation GO:0050865 1 0.011
protein sumoylation GO:0016925 2 0.011
regulation of systemic arterial blood pressure GO:0003073 1 0.011
protein localization GO:0008104 40 0.011
macromolecular complex disassembly GO:0032984 1 0.011
positive regulation of apoptotic signaling pathway GO:2001235 1 0.011
nucleobase containing compound metabolic process GO:0006139 274 0.011
regulation of blood vessel size GO:0050880 2 0.011
renal system development GO:0072001 94 0.011
cellular localization GO:0051641 97 0.011
ensheathment of neurons GO:0007272 18 0.011
homeostasis of number of cells within a tissue GO:0048873 4 0.011
regulation of transport GO:0051049 45 0.011
response to radiation GO:0009314 51 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
regulation of gene expression GO:0010468 265 0.011
negative regulation of apoptotic process GO:0043066 55 0.011
regulation of system process GO:0044057 40 0.011
detection of mechanical stimulus involved in sensory perception of sound GO:0050910 3 0.011
regulation of protein metabolic process GO:0051246 56 0.011
regulation of neurotransmitter secretion GO:0046928 1 0.011
microglia differentiation GO:0014004 1 0.011
regulation of cytokine production GO:0001817 3 0.010
bmp signaling pathway GO:0030509 52 0.010
antimicrobial humoral response GO:0019730 2 0.010
organelle fusion GO:0048284 3 0.010
guanosine containing compound metabolic process GO:1901068 4 0.010
regulation of dendrite morphogenesis GO:0048814 3 0.010
atp catabolic process GO:0006200 4 0.010
glial cell differentiation GO:0010001 42 0.010
cellular response to xenobiotic stimulus GO:0071466 35 0.010
regulation of autophagy GO:0010506 3 0.010
neural crest cell development GO:0014032 62 0.010
negative regulation of cell death GO:0060548 60 0.010
establishment of rna localization GO:0051236 3 0.010
camera type eye photoreceptor cell differentiation GO:0060219 19 0.010
regulation of cellular metabolic process GO:0031323 320 0.010
positive regulation of notch signaling pathway GO:0045747 3 0.010
single organism metabolic process GO:0044710 217 0.010
protein localization to plasma membrane GO:0072659 1 0.010
mitotic recombination GO:0006312 2 0.010
lamellipodium assembly GO:0030032 1 0.010
regulation of protein ubiquitination GO:0031396 3 0.010
developmental maturation GO:0021700 34 0.010

tmie disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.045
nervous system disease DOID:863 0 0.036
auditory system disease DOID:2742 0 0.036
nonsyndromic deafness DOID:0050563 0 0.036
sensory system disease DOID:0050155 0 0.036
immune system disease DOID:2914 0 0.023
disease of cellular proliferation DOID:14566 0 0.018
hematopoietic system disease DOID:74 0 0.017
organ system cancer DOID:0050686 0 0.013
cancer DOID:162 0 0.013