Danio rerio

38 known processes

tnfa

tumor necrosis factor a (TNF superfamily, member 2)

(Aliases: MGC152825)

tnfa biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of glucose transport GO:0010827 1 0.586
Mouse Rat
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.503
Mouse Rat
response to carbohydrate GO:0009743 3 0.501
lipid catabolic process GO:0016042 4 0.454
response to chemical GO:0042221 320 0.398
positive regulation of transport GO:0051050 2 0.386
Mouse Rat
response to biotic stimulus GO:0009607 97 0.385
protein complex localization GO:0031503 1 0.380
Mouse
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.374
Mouse
regulation of multicellular organismal process GO:0051239 277 0.362
Mouse Rat
cellular nitrogen compound metabolic process GO:0034641 290 0.350
Mouse
positive regulation of inflammatory response GO:0050729 1 0.330
Mouse Rat
response to arsenic containing substance GO:0046685 5 0.329
response to external stimulus GO:0009605 264 0.327
cellular response to lipopolysaccharide GO:0071222 3 0.326
Mouse
gene expression GO:0010467 252 0.313
Mouse
regulation of protein localization to nucleus GO:1900180 2 0.298
Mouse
nucleocytoplasmic transport GO:0006913 4 0.297
Mouse
regulation of glucose import GO:0046324 1 0.295
Mouse Rat
regulation of establishment of protein localization GO:0070201 4 0.281
Mouse Rat
regulation of biosynthetic process GO:0009889 250 0.277
Mouse
response to bacterium GO:0009617 58 0.277
peptide transport GO:0015833 1 0.263
Mouse
positive regulation of secretion by cell GO:1903532 1 0.263
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.262
Mouse Rat
response to monosaccharide GO:0034284 3 0.252
response to stress GO:0006950 263 0.243
immune system process GO:0002376 241 0.239
signal transduction GO:0007165 455 0.229
Zebrafish Mouse Rat Fly
protein localization to nucleus GO:0034504 3 0.227
Mouse
cellular response to external stimulus GO:0071496 2 0.225
cellular macromolecule metabolic process GO:0044260 391 0.217
Mouse
nuclear transport GO:0051169 4 0.216
Mouse
defense response to bacterium GO:0042742 22 0.213
cell surface receptor signaling pathway GO:0007166 325 0.212
Zebrafish Mouse Fly
regulation of protein import into nucleus GO:0042306 2 0.210
Mouse
regulation of inflammatory response GO:0050727 2 0.206
Mouse Rat
immune response GO:0006955 28 0.205
positive regulation of stress activated mapk cascade GO:0032874 3 0.204
Mouse
regulation of cytokine production GO:0001817 3 0.203
Mouse Rat
response to glucose GO:0009749 3 0.197
glucose import GO:0046323 2 0.195
Mouse Rat
regulation of hormone secretion GO:0046883 2 0.195
response to dsrna GO:0043331 7 0.190
nucleic acid metabolic process GO:0090304 244 0.189
Mouse
cellular component movement GO:0006928 335 0.186
Mouse
negative regulation of biological process GO:0048519 304 0.185
Mouse Rat Fly
mononuclear cell proliferation GO:0032943 1 0.183
hormone transport GO:0009914 2 0.182
regulation of protein targeting GO:1903533 2 0.178
Mouse
locomotion GO:0040011 313 0.175
Mouse
response to other organism GO:0051707 97 0.175
amide transport GO:0042886 12 0.175
Mouse
regulation of biological quality GO:0065008 263 0.174
Mouse Rat Fly
monosaccharide transport GO:0015749 6 0.172
Mouse Rat
cellular carbohydrate metabolic process GO:0044262 4 0.170
regulation of gene expression GO:0010468 265 0.167
Mouse
response to copper ion GO:0046688 13 0.165
negative regulation of secretion by cell GO:1903531 2 0.165
response to exogenous dsrna GO:0043330 6 0.163
regulation of protein transport GO:0051223 3 0.163
Mouse Rat
regulation of endocrine process GO:0044060 2 0.161
nucleobase containing compound biosynthetic process GO:0034654 205 0.160
Mouse
blood vessel development GO:0001568 246 0.160
regulation of nitrogen compound metabolic process GO:0051171 251 0.157
Mouse
protein secretion GO:0009306 1 0.157
Mouse
cellular response to endogenous stimulus GO:0071495 68 0.155
Mouse
defense response to other organism GO:0098542 33 0.154
single organism metabolic process GO:0044710 217 0.153
Mouse Fly
response to hexose GO:0009746 3 0.153
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.152
negative regulation of protein kinase activity GO:0006469 4 0.151
response to mechanical stimulus GO:0009612 24 0.149
Rat
regulation of macromolecule metabolic process GO:0060255 317 0.149
Mouse
transport GO:0006810 220 0.148
Mouse Rat Fly
response to organic substance GO:0010033 153 0.147
programmed cell death GO:0012501 119 0.146
Zebrafish Mouse Rat Fly
positive regulation of jnk cascade GO:0046330 3 0.145
Mouse
negative regulation of protein phosphorylation GO:0001933 4 0.145
nitrogen compound metabolic process GO:0006807 319 0.144
Mouse
negative regulation of secretion GO:0051048 2 0.143
aging GO:0007568 2 0.141
aromatic compound biosynthetic process GO:0019438 217 0.141
Mouse
hexose transport GO:0008645 6 0.140
Mouse Rat
sensory organ development GO:0007423 393 0.140
carbohydrate transport GO:0008643 13 0.138
Mouse Rat
regulation of signal transduction GO:0009966 225 0.137
Zebrafish Mouse Rat
protein targeting to nucleus GO:0044744 3 0.137
Mouse
response to hormone GO:0009725 48 0.136
multi organism process GO:0051704 134 0.135
maintenance of location GO:0051235 4 0.134
regulation of metabolic process GO:0019222 359 0.133
Mouse
central nervous system development GO:0007417 387 0.132
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.131
positive regulation of cell cycle GO:0045787 3 0.130
Rat
response to wounding GO:0009611 116 0.129
Mouse Rat
regulation of immune system process GO:0002682 34 0.129
Mouse
organic cyclic compound metabolic process GO:1901360 301 0.128
Mouse Fly
carboxylic acid metabolic process GO:0019752 22 0.127
regulation of primary metabolic process GO:0080090 311 0.126
Mouse
endocrine hormone secretion GO:0060986 2 0.123
nuclear import GO:0051170 3 0.123
Mouse
response to organic cyclic compound GO:0014070 51 0.122
negative regulation of map kinase activity GO:0043407 2 0.122
negative regulation of response to stimulus GO:0048585 104 0.120
establishment of protein localization to organelle GO:0072594 4 0.120
Mouse
biosynthetic process GO:0009058 294 0.119
Mouse
positive regulation of map kinase activity GO:0043406 3 0.119
regulation of nucleocytoplasmic transport GO:0046822 2 0.119
Mouse
organic substance biosynthetic process GO:1901576 289 0.119
Mouse
response to drug GO:0042493 3 0.117
Rat
oxoacid metabolic process GO:0043436 31 0.117
blood vessel morphogenesis GO:0048514 216 0.116
regulation of intracellular protein transport GO:0033157 3 0.115
Mouse
cellular response to chemical stimulus GO:0070887 157 0.112
Mouse
regulation of transcription dna templated GO:0006355 213 0.112
Mouse
amino acid transport GO:0006865 2 0.112
Rat
nucleic acid templated transcription GO:0097659 181 0.111
Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.111
Mouse
hemopoiesis GO:0030097 183 0.111
Mouse
cellular biosynthetic process GO:0044249 286 0.111
Mouse
response to nutrient GO:0007584 3 0.110
Rat
rna biosynthetic process GO:0032774 181 0.110
Mouse
tissue remodeling GO:0048771 4 0.109
cellular response to biotic stimulus GO:0071216 3 0.108
Mouse
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.108
Zebrafish
regulation of signaling GO:0023051 235 0.108
Zebrafish Mouse Rat Fly
glucose homeostasis GO:0042593 1 0.107
heterocycle metabolic process GO:0046483 290 0.104
Mouse
reactive nitrogen species metabolic process GO:2001057 0 0.104
negative regulation of kinase activity GO:0033673 4 0.101
regulation of cellular metabolic process GO:0031323 320 0.101
Mouse
regulation of cytoplasmic transport GO:1903649 4 0.101
Mouse
endocrine process GO:0050886 2 0.101
positive regulation of cytokine production GO:0001819 2 0.100
Mouse Rat
lipid storage GO:0019915 1 0.099
positive regulation of secretion GO:0051047 1 0.099
regulation of carbohydrate metabolic process GO:0006109 4 0.097
regulation of response to stimulus GO:0048583 269 0.097
Zebrafish Mouse Rat
positive regulation of response to external stimulus GO:0032103 9 0.097
Mouse Rat
response to glucocorticoid GO:0051384 1 0.097
response to corticosteroid GO:0031960 1 0.096
sensory system development GO:0048880 76 0.092
macromolecule biosynthetic process GO:0009059 227 0.092
Mouse
cell proliferation GO:0008283 80 0.092
Mouse Rat
positive regulation of cellular process GO:0048522 201 0.091
Zebrafish Mouse Rat
protein metabolic process GO:0019538 183 0.091
Mouse
regulation of macromolecule biosynthetic process GO:0010556 225 0.090
Mouse
response to abiotic stimulus GO:0009628 122 0.090
Rat
organic acid metabolic process GO:0006082 31 0.090
cellular aromatic compound metabolic process GO:0006725 295 0.090
Mouse Fly
regulation of defense response GO:0031347 14 0.089
Mouse Rat
protein modification process GO:0036211 100 0.088
Mouse
defense response GO:0006952 47 0.088
cellular protein metabolic process GO:0044267 129 0.088
Mouse
negative regulation of multicellular organismal process GO:0051241 69 0.086
Mouse
cognition GO:0050890 1 0.084
hematopoietic or lymphoid organ development GO:0048534 191 0.083
Mouse
embryonic organ development GO:0048568 381 0.083
cellular macromolecule biosynthetic process GO:0034645 224 0.082
Mouse
vasculature development GO:0001944 278 0.082
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.082
positive regulation of cell proliferation GO:0008284 15 0.082
Rat
single organism transport GO:0044765 206 0.082
Mouse Rat Fly
positive regulation of lipid metabolic process GO:0045834 1 0.081
regulation of protein catabolic process GO:0042176 1 0.081
system process GO:0003008 185 0.080
Rat
protein import GO:0017038 3 0.080
Mouse
negative regulation of mapk cascade GO:0043409 4 0.080
generation of neurons GO:0048699 385 0.079
Rat
rna metabolic process GO:0016070 219 0.078
Mouse
negative regulation of cell communication GO:0010648 96 0.078
Fly
carbohydrate metabolic process GO:0005975 12 0.077
Mouse
response to alkaloid GO:0043279 2 0.076
positive regulation of cellular metabolic process GO:0031325 94 0.075
Mouse
response to temperature stimulus GO:0009266 15 0.074
establishment of localization GO:0051234 244 0.074
Mouse Rat Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.073
Mouse
regulation of rna biosynthetic process GO:2001141 213 0.073
Mouse
negative regulation of catabolic process GO:0009895 3 0.073
nik nf kappab signaling GO:0038061 1 0.072
positive regulation of macromolecule metabolic process GO:0010604 93 0.072
Mouse
small molecule catabolic process GO:0044282 3 0.072
cell migration GO:0016477 237 0.072
Mouse
i kappab kinase nf kappab signaling GO:0007249 4 0.071
Mouse Rat
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.071
regulation of cell communication GO:0010646 232 0.071
Zebrafish Mouse Rat Fly
lymphocyte proliferation GO:0046651 1 0.071
cellular response to hormone stimulus GO:0032870 39 0.070
negative regulation of cellular process GO:0048523 283 0.070
Mouse Rat Fly
protein import into nucleus GO:0006606 3 0.069
Mouse
sensory organ morphogenesis GO:0090596 200 0.069
positive regulation of metabolic process GO:0009893 108 0.069
Mouse
positive regulation of signal transduction GO:0009967 56 0.069
Zebrafish Mouse Rat
digestive system development GO:0055123 289 0.069
angiogenesis GO:0001525 158 0.068
negative regulation of macromolecule metabolic process GO:0010605 76 0.067
Mouse
regulation of cell motility GO:2000145 46 0.066
anion transport GO:0006820 38 0.066
Rat
organonitrogen compound metabolic process GO:1901564 74 0.066
multi organism cellular process GO:0044764 2 0.066
cellular nitrogen compound biosynthetic process GO:0044271 218 0.065
Mouse
response to external biotic stimulus GO:0043207 97 0.065
positive regulation of immune system process GO:0002684 17 0.064
Mouse
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.063
Mouse
cell death GO:0008219 121 0.063
Zebrafish Mouse Rat Fly
glucose transport GO:0015758 6 0.063
Mouse Rat
amine metabolic process GO:0009308 2 0.063
positive regulation of defense response GO:0031349 9 0.063
Mouse Rat
negative regulation of cytokine production GO:0001818 1 0.063
cytokinesis GO:0000910 3 0.062
regulation of cell death GO:0010941 103 0.062
Zebrafish Mouse Rat
signal transduction in absence of ligand GO:0038034 1 0.062
circadian sleep wake cycle process GO:0022410 2 0.062
positive regulation of glucose transport GO:0010828 1 0.062
response to lipid GO:0033993 60 0.062
ameboidal type cell migration GO:0001667 143 0.061
regulation of system process GO:0044057 40 0.060
cellular response to organic substance GO:0071310 105 0.060
Mouse
fatty acid transport GO:0015908 1 0.060
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.060
Mouse
positive regulation of cell adhesion GO:0045785 1 0.060
nitric oxide biosynthetic process GO:0006809 2 0.060
localization of cell GO:0051674 244 0.060
Mouse
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.059
death GO:0016265 121 0.059
Zebrafish Mouse Rat Fly
cellular protein modification process GO:0006464 100 0.059
Mouse
regulation of nucleic acid templated transcription GO:1903506 213 0.058
Mouse
mitotic cell cycle GO:0000278 64 0.058
Rat
regulation of reactive oxygen species metabolic process GO:2000377 2 0.058
Mouse
small molecule metabolic process GO:0044281 77 0.058
regulation of dna replication GO:0006275 3 0.058
macromolecule modification GO:0043412 111 0.057
Mouse
regulation of cell activation GO:0050865 1 0.056
cytokine mediated signaling pathway GO:0019221 7 0.056
Mouse
response to endogenous stimulus GO:0009719 83 0.056
Mouse
alcohol biosynthetic process GO:0046165 2 0.056
peptide metabolic process GO:0006518 1 0.056
eye development GO:0001654 277 0.054
phosphate containing compound metabolic process GO:0006796 108 0.054
Mouse Fly
phosphorus metabolic process GO:0006793 109 0.054
Mouse Fly
cellular response to organic cyclic compound GO:0071407 38 0.054
carboxylic acid catabolic process GO:0046395 3 0.054
positive regulation of cell activation GO:0050867 1 0.053
apoptotic process GO:0006915 116 0.053
Zebrafish Mouse Rat Fly
response to lipopolysaccharide GO:0032496 13 0.053
carbohydrate homeostasis GO:0033500 1 0.053
mechanosensory lateral line system development GO:0048881 49 0.053
epithelial cell differentiation GO:0030855 116 0.052
negative regulation of signaling GO:0023057 96 0.052
Fly
single organism nuclear import GO:1902593 3 0.052
Mouse
negative regulation of cell migration GO:0030336 17 0.051
cellular ketone metabolic process GO:0042180 11 0.051
cellular response to drug GO:0035690 1 0.051
heart development GO:0007507 313 0.051
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.051
cellular protein catabolic process GO:0044257 4 0.051
negative regulation of cell motility GO:2000146 17 0.050
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.050
Mouse
enzyme linked receptor protein signaling pathway GO:0007167 106 0.050
negative regulation of hormone secretion GO:0046888 2 0.050
regulation of cellular ketone metabolic process GO:0010565 7 0.050
specification of symmetry GO:0009799 204 0.050
organic cyclic compound biosynthetic process GO:1901362 223 0.050
Mouse
negative regulation of dna metabolic process GO:0051053 4 0.050
connective tissue development GO:0061448 99 0.049
determination of bilateral symmetry GO:0009855 204 0.049
positive regulation of developmental process GO:0051094 50 0.049
Mouse Rat
positive regulation of jun kinase activity GO:0043507 2 0.049
neuron development GO:0048666 262 0.049
regulation of cellular component movement GO:0051270 55 0.049
response to oxygen containing compound GO:1901700 55 0.049
lipid oxidation GO:0034440 1 0.048
neuroblast proliferation GO:0007405 2 0.047
negative regulation of signal transduction GO:0009968 94 0.047
dorsal ventral pattern formation GO:0009953 125 0.047
collagen metabolic process GO:0032963 2 0.046
inner ear development GO:0048839 126 0.045
regulation of cytokine biosynthetic process GO:0042035 1 0.045
nuclear migration GO:0007097 3 0.045
developmental programmed cell death GO:0010623 4 0.045
regulation of cell cycle GO:0051726 52 0.045
Rat
cellular response to starvation GO:0009267 1 0.045
immune system development GO:0002520 191 0.044
Mouse
nitric oxide metabolic process GO:0046209 2 0.044
proteolysis GO:0006508 38 0.044
Mouse
skeletal system development GO:0001501 181 0.044
single organism localization GO:1902578 225 0.044
Mouse Rat Fly
cellular response to nutrient levels GO:0031669 2 0.044
regulation of anatomical structure morphogenesis GO:0022603 130 0.044
Mouse
regulation of metal ion transport GO:0010959 4 0.044
response to inorganic substance GO:0010035 38 0.043
positive regulation of biological process GO:0048518 253 0.043
Zebrafish Mouse Rat
regulation of epithelial cell proliferation GO:0050678 3 0.043
carbohydrate derivative biosynthetic process GO:1901137 43 0.043
regulation of multicellular organismal development GO:2000026 223 0.042
Mouse Rat
positive regulation of catabolic process GO:0009896 4 0.042
response to vitamin GO:0033273 3 0.042
autophagy GO:0006914 4 0.042
adult behavior GO:0030534 2 0.041
nucleobase containing compound metabolic process GO:0006139 274 0.041
Mouse
regulation of locomotion GO:0040012 55 0.041
positive regulation of cellular amine metabolic process GO:0033240 0 0.041
regulation of programmed cell death GO:0043067 101 0.041
Zebrafish Mouse Rat
negative regulation of dna replication GO:0008156 2 0.041
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.040
Mouse
intracellular signal transduction GO:0035556 85 0.040
Mouse Rat Fly
multicellular organismal macromolecule metabolic process GO:0044259 2 0.040
cellular response to oxygen levels GO:0071453 1 0.040
multicellular organismal metabolic process GO:0044236 2 0.039
positive regulation of rna metabolic process GO:0051254 59 0.039
Mouse
cellular response to extracellular stimulus GO:0031668 2 0.039
regulation of jun kinase activity GO:0043506 3 0.039
regulation of developmental process GO:0050793 247 0.039
Mouse Rat
negative regulation of cell death GO:0060548 60 0.039
head development GO:0060322 303 0.039
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.039
regulation of mrna processing GO:0050684 3 0.038
activation of immune response GO:0002253 9 0.038
mesoderm development GO:0007498 88 0.038
lateral line system development GO:0048925 76 0.038
regulation of cellular amino acid metabolic process GO:0006521 0 0.038
t cell activation GO:0042110 6 0.038
response to decreased oxygen levels GO:0036293 25 0.038
Rat
multicellular organismal homeostasis GO:0048871 29 0.038
Mouse
positive regulation of glucose import GO:0046326 1 0.038
cellular response to molecule of bacterial origin GO:0071219 3 0.037
Mouse
positive regulation of cellular biosynthetic process GO:0031328 68 0.037
Mouse
tissue regeneration GO:0042246 74 0.037
phosphorylation GO:0016310 69 0.037
Mouse Fly
positive regulation of signaling GO:0023056 56 0.037
Zebrafish Mouse Rat
circadian sleep wake cycle GO:0042745 2 0.037
regulation of cell migration GO:0030334 40 0.036
regulation of protein metabolic process GO:0051246 56 0.036
Mouse
lipid metabolic process GO:0006629 52 0.036
regulation of cellular protein metabolic process GO:0032268 52 0.036
Mouse
response to molecule of bacterial origin GO:0002237 14 0.036
extrinsic apoptotic signaling pathway GO:0097191 3 0.036
Zebrafish Mouse Fly
blood circulation GO:0008015 87 0.036
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.036
transcription from rna polymerase ii promoter GO:0006366 80 0.036
Mouse
reactive oxygen species biosynthetic process GO:1903409 1 0.035
cell cycle process GO:0022402 53 0.035
Rat
tube morphogenesis GO:0035239 349 0.035
homeostatic process GO:0042592 142 0.035
Mouse Fly
cellular amine metabolic process GO:0044106 2 0.035
response to virus GO:0009615 21 0.035
cellular response to lipid GO:0071396 39 0.035
Mouse
response to activity GO:0014823 14 0.034
Rat
transcription dna templated GO:0006351 181 0.034
Mouse
ear development GO:0043583 127 0.034
regulation of protein complex assembly GO:0043254 3 0.034
regulation of vasculature development GO:1901342 33 0.034
brain development GO:0007420 293 0.034
sequestering of metal ion GO:0051238 3 0.034
negative regulation of cellular component movement GO:0051271 18 0.034
organic acid catabolic process GO:0016054 3 0.033
cartilage development GO:0051216 96 0.033
regulation of proteolysis GO:0030162 24 0.033
Mouse
chordate embryonic development GO:0043009 271 0.033
negative regulation of locomotion GO:0040013 18 0.033
larval development GO:0002164 2 0.033
regulation of response to stress GO:0080134 36 0.033
Mouse Rat
establishment of localization in cell GO:0051649 77 0.033
Mouse
activation of mapk activity GO:0000187 3 0.033
positive regulation of cellular catabolic process GO:0031331 3 0.032
cellular response to stress GO:0033554 62 0.032
Mouse Fly
regulation of lipid catabolic process GO:0050994 2 0.032
wound healing GO:0042060 90 0.032
digestive tract development GO:0048565 265 0.032
regulation of transport GO:0051049 45 0.032
Mouse Rat
regulation of intracellular signal transduction GO:1902531 57 0.031
Mouse Rat
immune effector process GO:0002252 23 0.031
Mouse
cell motility GO:0048870 244 0.031
Mouse
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.031
signal transduction by phosphorylation GO:0023014 18 0.031
Mouse Fly
positive regulation of response to wounding GO:1903036 5 0.030
Mouse Rat
response to oxygen levels GO:0070482 25 0.030
Rat
cellular lipid catabolic process GO:0044242 3 0.030
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.030
Mouse
regulation of cellular component organization GO:0051128 86 0.030
Rat
chemotaxis GO:0006935 104 0.030
regulation of localization GO:0032879 104 0.030
Mouse Rat
regulation of cellular amine metabolic process GO:0033238 0 0.030
insulin like growth factor receptor signaling pathway GO:0048009 4 0.030
urogenital system development GO:0001655 97 0.030
negative regulation of metabolic process GO:0009892 86 0.030
Mouse
antimicrobial humoral response GO:0019730 2 0.030
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.029
Mouse
response to nutrient levels GO:0031667 10 0.029
Rat
gastrulation GO:0007369 208 0.029
hepaticobiliary system development GO:0061008 98 0.029
regionalization GO:0003002 274 0.029
calcium ion transport into cytosol GO:0060402 3 0.029
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.029
sensory perception of pain GO:0019233 1 0.029
Rat
regulation of calcium ion transport GO:0051924 2 0.029
digestive tract morphogenesis GO:0048546 231 0.029
positive regulation of cell division GO:0051781 2 0.028
Rat
leukocyte differentiation GO:0002521 25 0.028
Mouse
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.028
epithelial tube morphogenesis GO:0060562 148 0.028
negative regulation of protein complex assembly GO:0031333 1 0.028
regulation of molecular function GO:0065009 70 0.028
Mouse
protein phosphorylation GO:0006468 47 0.028
Mouse
liver development GO:0001889 96 0.028
neuron differentiation GO:0030182 353 0.028
hindbrain development GO:0030902 91 0.027
hormone secretion GO:0046879 2 0.027
neutrophil migration GO:1990266 10 0.027
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.027
Mouse
negative regulation of sequestering of calcium ion GO:0051283 4 0.027
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.027
regulation of glial cell differentiation GO:0045685 4 0.027
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.027
Mouse
single organism biosynthetic process GO:0044711 71 0.027
embryonic organ morphogenesis GO:0048562 274 0.027
embryonic heart tube development GO:0035050 133 0.027
cellular component morphogenesis GO:0032989 336 0.027
fat soluble vitamin metabolic process GO:0006775 4 0.026
cell morphogenesis involved in differentiation GO:0000904 195 0.026
chemical homeostasis GO:0048878 49 0.026
negative regulation of apoptotic process GO:0043066 55 0.026
regulation of binding GO:0051098 3 0.026
heterocycle biosynthetic process GO:0018130 215 0.026
Mouse
regulation of mitotic cell cycle GO:0007346 25 0.026
Rat
regulation of angiogenesis GO:0045765 26 0.026
embryo development ending in birth or egg hatching GO:0009792 271 0.026
cytokine metabolic process GO:0042107 1 0.026
positive regulation of cellular component biogenesis GO:0044089 3 0.026
carbohydrate biosynthetic process GO:0016051 1 0.026
regulation of membrane potential GO:0042391 23 0.025
Rat
regulation of cell cell adhesion GO:0022407 13 0.025
adherens junction organization GO:0034332 4 0.025
organonitrogen compound biosynthetic process GO:1901566 47 0.025
regulation of phosphate metabolic process GO:0019220 43 0.025
Mouse
peptidyl lysine acetylation GO:0018394 2 0.025
morphogenesis of an epithelium GO:0002009 333 0.025
Mouse
regulation of protein ubiquitination GO:0031396 3 0.025
positive regulation of muscle cell differentiation GO:0051149 1 0.025
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.024
Mouse
circulatory system process GO:0003013 87 0.024
synaptic target recognition GO:0008039 1 0.024
regulation of response to external stimulus GO:0032101 31 0.024
Mouse Rat
negative regulation of epithelial cell proliferation GO:0050680 1 0.024
positive regulation of response to stimulus GO:0048584 80 0.024
Zebrafish Mouse Rat
multicellular organism growth GO:0035264 4 0.023
cellular localization GO:0051641 97 0.023
Mouse
cellular response to hypoxia GO:0071456 1 0.023
regulation of production of molecular mediator of immune response GO:0002700 1 0.023
Mouse
humoral immune response GO:0006959 5 0.023
Mouse
cellular response to oxygen containing compound GO:1901701 20 0.023
Mouse
regulation of hormone levels GO:0010817 21 0.023
positive regulation of rna biosynthetic process GO:1902680 57 0.023
Mouse
cell cycle GO:0007049 93 0.023
Rat
regulation of meiotic cell cycle GO:0051445 1 0.023
fatty acid oxidation GO:0019395 1 0.023
protein kinase b signaling GO:0043491 9 0.023
Mouse
positive regulation of cytokine biosynthetic process GO:0042108 1 0.023
cell division GO:0051301 20 0.023
Rat
regulation of circadian rhythm GO:0042752 4 0.022
interspecies interaction between organisms GO:0044419 4 0.022
Mouse
modification dependent protein catabolic process GO:0019941 3 0.022
toll like receptor signaling pathway GO:0002224 4 0.022
organelle organization GO:0006996 227 0.022
Rat
taxis GO:0042330 109 0.022
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.022
regulation of sequestering of calcium ion GO:0051282 4 0.022
regulation of rna metabolic process GO:0051252 224 0.022
Mouse
axon development GO:0061564 166 0.022
negative regulation of rna metabolic process GO:0051253 48 0.022
Mouse
single organism organelle organization GO:1902589 199 0.022
Rat
steroid hormone secretion GO:0035929 1 0.022
response to metal ion GO:0010038 34 0.022
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.021
Mouse
protein acetylation GO:0006473 2 0.021
intracellular transport GO:0046907 32 0.021
Mouse
granulocyte migration GO:0097530 11 0.021
response to hypoxia GO:0001666 25 0.021
Rat
response to nicotine GO:0035094 2 0.021
astrocyte differentiation GO:0048708 1 0.021
cellular lipid metabolic process GO:0044255 36 0.021
modification dependent macromolecule catabolic process GO:0043632 3 0.021
single organism intracellular transport GO:1902582 25 0.021
Mouse
neuromast development GO:0048884 46 0.021
regulation of protein binding GO:0043393 3 0.021
monocarboxylic acid catabolic process GO:0072329 3 0.021
negative regulation of defense response GO:0031348 2 0.021
erk1 and erk2 cascade GO:0070371 4 0.020
regulation of tube size GO:0035150 2 0.020
neurological system process GO:0050877 62 0.020
Rat
proteasomal protein catabolic process GO:0010498 2 0.020
regulation of immune response GO:0050776 14 0.020
Mouse
regulation of reproductive process GO:2000241 4 0.020

tnfa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.099
cancer DOID:162 0 0.035
disease of cellular proliferation DOID:14566 0 0.035
organ system cancer DOID:0050686 0 0.035
nervous system disease DOID:863 0 0.028