Danio rerio

15 known processes

tnfrsf1a

tumor necrosis factor receptor superfamily, member 1a

(Aliases: wu:fj65b10,zgc:85914)

tnfrsf1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to bacterium GO:0009617 58 0.557
regulation of multicellular organismal process GO:0051239 277 0.510
Rat
cell migration GO:0016477 237 0.492
multi organism process GO:0051704 134 0.437
regulation of multicellular organismal development GO:2000026 223 0.369
Rat
response to external stimulus GO:0009605 264 0.340
regulation of developmental process GO:0050793 247 0.318
Rat
response to abiotic stimulus GO:0009628 122 0.309
Human Rat
cell projection organization GO:0030030 284 0.300
immune system process GO:0002376 241 0.291
signal transduction GO:0007165 455 0.285
Human Mouse Rat
regulation of synapse organization GO:0050807 3 0.261
regulation of protein complex assembly GO:0043254 3 0.247
localization of cell GO:0051674 244 0.245
regulation of biological quality GO:0065008 263 0.240
liver development GO:0001889 96 0.237
synaptic growth at neuromuscular junction GO:0051124 2 0.233
regulation of metabolic process GO:0019222 359 0.232
Human Zebrafish Mouse Rat
regulation of programmed cell death GO:0043067 101 0.227
Zebrafish Rat
regulation of transcription dna templated GO:0006355 213 0.226
Human Mouse
positive regulation of cellular component biogenesis GO:0044089 3 0.221
peptidyl serine phosphorylation GO:0018105 1 0.217
single organism metabolic process GO:0044710 217 0.212
regulation of apoptotic process GO:0042981 98 0.206
Zebrafish Rat
stem cell maintenance GO:0019827 4 0.206
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.205
locomotion GO:0040011 313 0.200
multicellular organism growth GO:0035264 4 0.195
nucleobase containing compound metabolic process GO:0006139 274 0.189
Human Mouse
response to other organism GO:0051707 97 0.186
peptidyl serine modification GO:0018209 2 0.185
protein secretion GO:0009306 1 0.181
phagocytosis GO:0006909 3 0.178
response to hypoxia GO:0001666 25 0.177
Rat
programmed cell death GO:0012501 119 0.172
Zebrafish Mouse Rat
cellular nitrogen compound metabolic process GO:0034641 290 0.168
Human Mouse
defense response GO:0006952 47 0.166
positive regulation of cellular process GO:0048522 201 0.158
Human Zebrafish Mouse Rat
positive regulation of biological process GO:0048518 253 0.157
Human Zebrafish Mouse Rat
regulation of meiotic cell cycle GO:0051445 1 0.153
muscle structure development GO:0061061 196 0.150
negative regulation of biological process GO:0048519 304 0.148
Human Rat
regulation of cellular component organization GO:0051128 86 0.147
cellular component assembly GO:0022607 170 0.144
Rat
cell surface receptor signaling pathway GO:0007166 325 0.142
Mouse Rat
regulation of nitrogen compound metabolic process GO:0051171 251 0.140
Human Mouse
taxis GO:0042330 109 0.138
generation of neurons GO:0048699 385 0.134
aromatic compound biosynthetic process GO:0019438 217 0.131
Human Mouse
cell motility GO:0048870 244 0.130
cellular component movement GO:0006928 335 0.128
gene expression GO:0010467 252 0.125
Human Mouse Rat
regulation of primary metabolic process GO:0080090 311 0.125
Human Zebrafish Mouse
cellular ketone metabolic process GO:0042180 11 0.122
regulation of synapse assembly GO:0051963 3 0.122
membrane invagination GO:0010324 1 0.121
regulation of nucleic acid templated transcription GO:1903506 213 0.121
Human Mouse
cellular biosynthetic process GO:0044249 286 0.121
Human Mouse
regulation of cell death GO:0010941 103 0.119
Zebrafish Rat
cortical cytoskeleton organization GO:0030865 1 0.119
response to stress GO:0006950 263 0.118
heterocycle metabolic process GO:0046483 290 0.117
Human Mouse Rat
nucleobase containing compound biosynthetic process GO:0034654 205 0.117
Human Mouse
organic substance biosynthetic process GO:1901576 289 0.115
Human Mouse
regulation of multicellular organism growth GO:0040014 4 0.114
regulation of cellular metabolic process GO:0031323 320 0.114
Human Zebrafish Mouse
nitrogen compound metabolic process GO:0006807 319 0.112
Human Mouse Rat
blood vessel morphogenesis GO:0048514 216 0.111
Rat
response to light stimulus GO:0009416 46 0.110
apoptotic process GO:0006915 116 0.110
Zebrafish Mouse Rat
negative regulation of cellular process GO:0048523 283 0.108
Rat
maintenance of location GO:0051235 4 0.106
cell death GO:0008219 121 0.105
Zebrafish Mouse Rat
regulation of establishment of protein localization GO:0070201 4 0.105
Rat
response to oxidative stress GO:0006979 11 0.103
oxoacid metabolic process GO:0043436 31 0.103
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.101
organic cyclic compound biosynthetic process GO:1901362 223 0.101
Human Mouse
meiotic nuclear division GO:0007126 4 0.101
cytoskeleton organization GO:0007010 96 0.101
regulation of cellular ketone metabolic process GO:0010565 7 0.098
single organism localization GO:1902578 225 0.098
Rat
larval development GO:0002164 2 0.097
homeostasis of number of cells GO:0048872 62 0.095
response to external biotic stimulus GO:0043207 97 0.095
response to biotic stimulus GO:0009607 97 0.092
biosynthetic process GO:0009058 294 0.092
Human Mouse
cellular component morphogenesis GO:0032989 336 0.091
secondary metabolic process GO:0019748 3 0.090
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.090
Human Mouse
cellular component biogenesis GO:0044085 178 0.090
Rat
enzyme linked receptor protein signaling pathway GO:0007167 106 0.088
female sex differentiation GO:0046660 4 0.086
phagocytosis engulfment GO:0006911 1 0.086
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.086
regulation of signaling GO:0023051 235 0.085
Human
cellular aromatic compound metabolic process GO:0006725 295 0.083
Human Mouse Rat
negative regulation of cellular metabolic process GO:0031324 77 0.082
regulation of macromolecule metabolic process GO:0060255 317 0.082
Human Zebrafish Mouse Rat
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.081
cortical actin cytoskeleton organization GO:0030866 1 0.081
aging GO:0007568 2 0.080
positive regulation of transport GO:0051050 2 0.079
Rat
stem cell differentiation GO:0048863 117 0.078
cellular response to chemical stimulus GO:0070887 157 0.076
Mouse Rat
stem cell development GO:0048864 82 0.076
cellular amine metabolic process GO:0044106 2 0.075
adult behavior GO:0030534 2 0.074
hemopoiesis GO:0030097 183 0.074
specification of symmetry GO:0009799 204 0.074
locomotor rhythm GO:0045475 3 0.072
regulation of localization GO:0032879 104 0.072
Rat
nucleic acid templated transcription GO:0097659 181 0.072
Human Mouse
response to ketone GO:1901654 1 0.072
protein polymerization GO:0051258 4 0.072
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.072
regulation of filopodium assembly GO:0051489 2 0.071
regulation of protein polymerization GO:0032271 2 0.070
organic acid metabolic process GO:0006082 31 0.070
growth GO:0040007 174 0.069
developmental growth GO:0048589 166 0.069
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.068
pyruvate metabolic process GO:0006090 1 0.068
chemotaxis GO:0006935 104 0.066
extrinsic apoptotic signaling pathway GO:0097191 3 0.065
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.065
cellular macromolecule metabolic process GO:0044260 391 0.064
Human Zebrafish Mouse
single organism transport GO:0044765 206 0.064
Rat
phosphorus metabolic process GO:0006793 109 0.063
Human
glucose homeostasis GO:0042593 1 0.063
regulation of dna templated transcription in response to stress GO:0043620 0 0.063
cell morphogenesis GO:0000902 289 0.063
axonogenesis GO:0007409 152 0.063
neuron differentiation GO:0030182 353 0.062
carboxylic acid metabolic process GO:0019752 22 0.061
small molecule metabolic process GO:0044281 77 0.061
muscle tissue development GO:0060537 110 0.061
posterior lateral line neuromast hair cell development GO:0035677 3 0.061
melanin metabolic process GO:0006582 2 0.061
positive regulation of programmed cell death GO:0043068 29 0.060
Zebrafish Rat
cellular macromolecule biosynthetic process GO:0034645 224 0.059
Human Mouse
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.059
regulation of cell projection organization GO:0031344 44 0.058
defense response to bacterium GO:0042742 22 0.058
axon guidance GO:0007411 86 0.058
guanosine containing compound metabolic process GO:1901068 4 0.058
angiogenesis GO:0001525 158 0.057
Rat
positive regulation of apoptotic process GO:0043065 29 0.057
Zebrafish Rat
germ line stem cell maintenance GO:0030718 2 0.057
rna metabolic process GO:0016070 219 0.056
Human Mouse
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.056
regulation of anatomical structure size GO:0090066 33 0.055
lamellipodium organization GO:0097581 1 0.055
central nervous system development GO:0007417 387 0.055
cellular carbohydrate metabolic process GO:0044262 4 0.054
regulation of cell differentiation GO:0045595 142 0.054
negative regulation of protein phosphorylation GO:0001933 4 0.053
rhythmic process GO:0048511 21 0.053
regulation of dna replication GO:0006275 3 0.053
regulation of cellular biosynthetic process GO:0031326 245 0.052
Human Mouse
development of primary female sexual characteristics GO:0046545 4 0.052
ion transport GO:0006811 114 0.051
regulation of developmental growth GO:0048638 38 0.051
positive regulation of transcription dna templated GO:0045893 57 0.051
Human Mouse
nuclear migration GO:0007097 3 0.050
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.049
positive regulation of cellular protein metabolic process GO:0032270 22 0.049
Human Zebrafish
regulation of cellular amine metabolic process GO:0033238 0 0.049
immune system development GO:0002520 191 0.049
positive regulation of cell adhesion GO:0045785 1 0.049
regulation of signal transduction GO:0009966 225 0.049
Human
myeloid cell homeostasis GO:0002262 56 0.049
hormone biosynthetic process GO:0042446 3 0.049
heterocycle biosynthetic process GO:0018130 215 0.048
Human Mouse
actomyosin structure organization GO:0031032 53 0.048
regulation of cysteine type endopeptidase activity GO:2000116 21 0.048
Zebrafish
regulation of cell shape GO:0008360 1 0.048
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.048
Zebrafish
organonitrogen compound metabolic process GO:1901564 74 0.048
Rat
gtp catabolic process GO:0006184 2 0.048
response to organic substance GO:0010033 153 0.047
Mouse Rat
carbohydrate homeostasis GO:0033500 1 0.047
death GO:0016265 121 0.047
Zebrafish Mouse Rat
amine metabolic process GO:0009308 2 0.047
protein complex biogenesis GO:0070271 30 0.047
Rat
transcription dna templated GO:0006351 181 0.046
Human Mouse
stem cell proliferation GO:0072089 4 0.046
macromolecular complex assembly GO:0065003 35 0.046
Rat
interaction with host GO:0051701 4 0.045
positive regulation of developmental process GO:0051094 50 0.045
Rat
regulation of gene expression GO:0010468 265 0.045
Human Mouse Rat
cell projection morphogenesis GO:0048858 244 0.045
neuron projection guidance GO:0097485 86 0.044
embryonic organ development GO:0048568 381 0.044
posterior lateral line neuromast hair cell differentiation GO:0048923 8 0.044
cellular component assembly involved in morphogenesis GO:0010927 107 0.044
anterior posterior pattern specification GO:0009952 152 0.044
guanosine containing compound catabolic process GO:1901069 2 0.044
positive regulation of protein complex assembly GO:0031334 2 0.044
regulation of rna metabolic process GO:0051252 224 0.044
Human Mouse
heart development GO:0007507 313 0.043
response to endogenous stimulus GO:0009719 83 0.043
Rat
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.042
Human Mouse
regulation of nervous system development GO:0051960 90 0.042
response to chemical GO:0042221 320 0.042
Mouse Rat
regulation of intracellular protein transport GO:0033157 3 0.041
Rat
regulation of cell development GO:0060284 100 0.041
positive regulation of neuron apoptotic process GO:0043525 1 0.041
Rat
stem cell division GO:0017145 1 0.041
lipid homeostasis GO:0055088 3 0.041
negative regulation of protein complex assembly GO:0031333 1 0.041
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.041
Human
regulation of cell projection assembly GO:0060491 4 0.041
actin cytoskeleton organization GO:0030036 63 0.041
system process GO:0003008 185 0.040
actin filament based process GO:0030029 64 0.040
myeloid cell differentiation GO:0030099 86 0.040
hepaticobiliary system development GO:0061008 98 0.040
epithelial cell differentiation GO:0030855 116 0.040
urogenital system development GO:0001655 97 0.040
viral process GO:0016032 1 0.040
erythrocyte differentiation GO:0030218 54 0.040
renal system development GO:0072001 94 0.039
positive regulation of cell death GO:0010942 29 0.039
Zebrafish Rat
vasculature development GO:0001944 278 0.039
Rat
protein localization GO:0008104 40 0.039
Rat
oxidation reduction process GO:0055114 41 0.039
blood vessel development GO:0001568 246 0.039
Rat
skeletal system morphogenesis GO:0048705 102 0.039
regulation of growth GO:0040008 42 0.038
regulation of response to stimulus GO:0048583 269 0.038
Human Mouse
cell part morphogenesis GO:0032990 246 0.038
regulation of microtubule cytoskeleton organization GO:0070507 3 0.038
spermatid development GO:0007286 2 0.037
response to carbohydrate GO:0009743 3 0.037
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.037
Human Mouse
neuron development GO:0048666 262 0.037
axon development GO:0061564 166 0.037
determination of bilateral symmetry GO:0009855 204 0.037
negative regulation of signaling GO:0023057 96 0.037
membrane organization GO:0061024 21 0.036
blood circulation GO:0008015 87 0.036
positive regulation of synapse assembly GO:0051965 1 0.036
neuromuscular synaptic transmission GO:0007274 2 0.036
gtp metabolic process GO:0046039 4 0.036
cell migration involved in gastrulation GO:0042074 79 0.036
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.036
mitochondrion organization GO:0007005 4 0.036
epidermal cell differentiation GO:0009913 36 0.035
response to decreased oxygen levels GO:0036293 25 0.035
Rat
gland development GO:0048732 143 0.035
regulation of cytokine production GO:0001817 3 0.035
Rat
response to wounding GO:0009611 116 0.035
Human Mouse Rat
rna biosynthetic process GO:0032774 181 0.035
Human Mouse
nucleocytoplasmic transport GO:0006913 4 0.034
Rat
positive regulation of apoptotic signaling pathway GO:2001235 1 0.034
cellular response to reactive oxygen species GO:0034614 2 0.034
transcription from rna polymerase ii promoter GO:0006366 80 0.034
Human Mouse
protein localization to plasma membrane GO:0072659 1 0.034
protein localization to nucleus GO:0034504 3 0.034
Rat
female gonad development GO:0008585 4 0.034
organic cyclic compound metabolic process GO:1901360 301 0.034
Human Mouse Rat
protein import GO:0017038 3 0.033
Rat
circadian rhythm GO:0007623 19 0.033
response to nitrogen compound GO:1901698 19 0.033
Rat
fertilization GO:0009566 3 0.033
transport GO:0006810 220 0.033
Rat
response to oxygen containing compound GO:1901700 55 0.033
Rat
macromolecule biosynthetic process GO:0009059 227 0.033
Human Mouse
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.033
striated muscle cell development GO:0055002 108 0.033
cellular response to endogenous stimulus GO:0071495 68 0.032
Rat
negative regulation of kinase activity GO:0033673 4 0.032
regulation of stem cell differentiation GO:2000736 4 0.032
neuron projection morphogenesis GO:0048812 161 0.032
cellular protein complex assembly GO:0043623 19 0.032
positive regulation of metabolic process GO:0009893 108 0.032
Human Zebrafish Mouse Rat
regulation of cellular amino acid metabolic process GO:0006521 0 0.032
organelle assembly GO:0070925 110 0.032
protein metabolic process GO:0019538 183 0.032
Human Zebrafish
proteolysis GO:0006508 38 0.031
Zebrafish
regulation of protein transport GO:0051223 3 0.031
Rat
regulation of neurogenesis GO:0050767 87 0.031
neuromast development GO:0048884 46 0.031
cell morphogenesis involved in differentiation GO:0000904 195 0.031
skeletal system development GO:0001501 181 0.031
immune response GO:0006955 28 0.031
actin polymerization or depolymerization GO:0008154 2 0.031
regulation of protein ubiquitination GO:0031396 3 0.031
cytoskeleton dependent cytokinesis GO:0061640 3 0.031
regulation of locomotion GO:0040012 55 0.031
lamellipodium assembly GO:0030032 1 0.031
lipid storage GO:0019915 1 0.031
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.031
Human Mouse
cell proliferation GO:0008283 80 0.030
positive regulation of cell cycle GO:0045787 3 0.030
muscle organ development GO:0007517 101 0.030
response to temperature stimulus GO:0009266 15 0.030
phosphorylation GO:0016310 69 0.030
Human
digestive tract development GO:0048565 265 0.030
positive regulation of catabolic process GO:0009896 4 0.030
bmp signaling pathway GO:0030509 52 0.030
negative regulation of rna metabolic process GO:0051253 48 0.030
regulation of bmp signaling pathway GO:0030510 39 0.030
regulation of epithelial cell proliferation GO:0050678 3 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.030
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.030
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.030
Human Mouse
retina morphogenesis in camera type eye GO:0060042 79 0.030
cytokinesis GO:0000910 3 0.029
protein complex assembly GO:0006461 30 0.029
Rat
membrane fusion GO:0061025 2 0.029
inorganic cation transmembrane transport GO:0098662 50 0.029
response to radiation GO:0009314 51 0.029
negative regulation of mapk cascade GO:0043409 4 0.029
mitochondrial transport GO:0006839 2 0.029
regulation of molecular function GO:0065009 70 0.029
Zebrafish
specification of organ axis polarity GO:0010084 2 0.029
cellular protein catabolic process GO:0044257 4 0.028
locomotory behavior GO:0007626 34 0.028
regulation of neural precursor cell proliferation GO:2000177 3 0.028
regulation of cell substrate adhesion GO:0010810 1 0.028
cation transport GO:0006812 81 0.028
regulation of cellular component size GO:0032535 30 0.028
establishment of protein localization to plasma membrane GO:0090002 1 0.028
regulation of wound healing GO:0061041 2 0.027
homeostatic process GO:0042592 142 0.027
i kappab kinase nf kappab signaling GO:0007249 4 0.027
Human
negative regulation of cell death GO:0060548 60 0.027
Rat
cellular amino acid metabolic process GO:0006520 7 0.027
regulation of protein import into nucleus GO:0042306 2 0.027
Rat
cell substrate adhesion GO:0031589 4 0.027
pancreas development GO:0031016 84 0.027
erythrocyte homeostasis GO:0034101 55 0.027
hematopoietic or lymphoid organ development GO:0048534 191 0.027
proteasomal protein catabolic process GO:0010498 2 0.027
negative regulation of cellular biosynthetic process GO:0031327 55 0.026
regulation of rna biosynthetic process GO:2001141 213 0.026
Human Mouse
nucleic acid metabolic process GO:0090304 244 0.026
Human Mouse
positive regulation of secretion GO:0051047 1 0.026
skin development GO:0043588 54 0.026
positive regulation of oocyte development GO:0060282 1 0.026
macromolecule localization GO:0033036 54 0.026
Rat
regulation of sequestering of calcium ion GO:0051282 4 0.026
negative regulation of rna biosynthetic process GO:1902679 45 0.025
regulation of cell communication GO:0010646 232 0.025
Human
regulation of nucleoside metabolic process GO:0009118 2 0.025
response to amino acid GO:0043200 2 0.025
Rat
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.025
Human Mouse
regulation of response to cytokine stimulus GO:0060759 3 0.025
regulation of behavior GO:0050795 24 0.025
regulation of cell motility GO:2000145 46 0.025
response to uv GO:0009411 3 0.025
positive regulation of rna metabolic process GO:0051254 59 0.025
Human Mouse
cellular component disassembly GO:0022411 1 0.025
ovulation cycle GO:0042698 2 0.024
heart morphogenesis GO:0003007 156 0.024
embryonic skeletal system development GO:0048706 97 0.024
negative regulation of cell communication GO:0010648 96 0.024
entrainment of circadian clock GO:0009649 2 0.024
cellular macromolecule localization GO:0070727 21 0.024
Rat
regulation of chromosome segregation GO:0051983 1 0.024
regulation of protein metabolic process GO:0051246 56 0.024
Human Zebrafish
modulation by virus of host morphology or physiology GO:0019048 1 0.024
superoxide metabolic process GO:0006801 2 0.024
negative regulation of multicellular organismal process GO:0051241 69 0.024
Rat
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.024
single organism membrane fusion GO:0044801 2 0.023
multi organism reproductive process GO:0044703 36 0.023
germ cell development GO:0007281 22 0.023
regulation of binding GO:0051098 3 0.023
pronuclear migration GO:0035046 1 0.023
positive regulation of notch signaling pathway GO:0045747 3 0.023
neurological system process GO:0050877 62 0.023
negative regulation of mitosis GO:0045839 3 0.023
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.023
regulation of cell activation GO:0050865 1 0.023
multicellular organism reproduction GO:0032504 35 0.022
regulation of protein catabolic process GO:0042176 1 0.022
regulation of cell migration GO:0030334 40 0.022
actin filament polymerization GO:0030041 2 0.022
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.022
asymmetric protein localization GO:0008105 6 0.022
chondrocyte development GO:0002063 4 0.022
dorsal ventral pattern formation GO:0009953 125 0.022
cellular nitrogen compound biosynthetic process GO:0044271 218 0.022
Human Mouse
positive regulation of secretion by cell GO:1903532 1 0.022
production of molecular mediator of immune response GO:0002440 2 0.022
organelle organization GO:0006996 227 0.022
developmental growth involved in morphogenesis GO:0060560 86 0.022
positive regulation of immune system process GO:0002684 17 0.022
striated muscle tissue development GO:0014706 110 0.022
regulation of metal ion transport GO:0010959 4 0.022
embryonic heart tube development GO:0035050 133 0.022
tube morphogenesis GO:0035239 349 0.022
tissue remodeling GO:0048771 4 0.022
cardiac muscle tissue development GO:0048738 48 0.022
reactive oxygen species metabolic process GO:0072593 6 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.021
innate immune response GO:0045087 13 0.021
response to acid chemical GO:0001101 17 0.021
Rat
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 10 0.021
Zebrafish
cellular protein modification process GO:0006464 100 0.021
Human
single organism biosynthetic process GO:0044711 71 0.021
negative regulation of protein kinase activity GO:0006469 4 0.021
nuclear transport GO:0051169 4 0.021
Rat
negative regulation of cell migration GO:0030336 17 0.021
cellular protein metabolic process GO:0044267 129 0.021
Human Zebrafish
regulation of receptor activity GO:0010469 2 0.021
microtubule organizing center organization GO:0031023 1 0.021
exocytosis GO:0006887 1 0.021
glial cell migration GO:0008347 3 0.020
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.020
positive regulation of cellular catabolic process GO:0031331 3 0.020
cell cell signaling GO:0007267 52 0.020
cellular response to stress GO:0033554 62 0.020
Mouse
retina development in camera type eye GO:0060041 146 0.020
camera type eye development GO:0043010 222 0.020
spermatid differentiation GO:0048515 2 0.020
signal transduction in absence of ligand GO:0038034 1 0.020
regulation of protein localization to nucleus GO:1900180 2 0.020
Rat
b cell activation GO:0042113 2 0.020
camera type eye morphogenesis GO:0048593 108 0.020
positive regulation of lipid metabolic process GO:0045834 1 0.020
negative regulation of catabolic process GO:0009895 3 0.020
convergent extension GO:0060026 118 0.020
purine nucleotide metabolic process GO:0006163 27 0.020
regulation of establishment of protein localization to plasma membrane GO:0090003 1 0.020
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.020
negative regulation of immune response GO:0050777 2 0.020
response to arsenic containing substance GO:0046685 5 0.019
peripheral nervous system development GO:0007422 55 0.019
meiotic cell cycle process GO:1903046 3 0.019
response to drug GO:0042493 3 0.019
centrosome organization GO:0051297 1 0.019
regulation of exocytosis GO:0017157 1 0.019
peripheral nervous system neuron differentiation GO:0048934 28 0.019
regulation of inflammatory response GO:0050727 2 0.019
Human Mouse
regionalization GO:0003002 274 0.019
reproductive process GO:0022414 40 0.019
establishment of localization GO:0051234 244 0.019
Rat
gamete generation GO:0007276 33 0.019
antimicrobial humoral response GO:0019730 2 0.019
organ regeneration GO:0031100 1 0.019
single organism reproductive process GO:0044702 40 0.019
single organism cell adhesion GO:0098602 29 0.019
regulation of muscle contraction GO:0006937 3 0.019
positive regulation of gene expression GO:0010628 71 0.019
Human Mouse Rat
multi organism cellular process GO:0044764 2 0.019
chordate embryonic development GO:0043009 271 0.019
keratinocyte differentiation GO:0030216 0 0.019
cell projection assembly GO:0030031 64 0.018
head development GO:0060322 303 0.018
receptor internalization GO:0031623 2 0.018
cell substrate junction assembly GO:0007044 2 0.018
regulation of cellular component movement GO:0051270 55 0.018
hatching GO:0035188 4 0.018
macromolecule modification GO:0043412 111 0.018
Human
regulation of carbohydrate metabolic process GO:0006109 4 0.018
response to hydrogen peroxide GO:0042542 3 0.018
digestive tract morphogenesis GO:0048546 231 0.018
negative regulation of metabolic process GO:0009892 86 0.018
Rat
modification dependent protein catabolic process GO:0019941 3 0.018
regulation of circadian rhythm GO:0042752 4 0.018
regulation of cellular component biogenesis GO:0044087 12 0.018
cellular response to oxygen levels GO:0071453 1 0.018
interspecies interaction between organisms GO:0044419 4 0.018
single organism cellular localization GO:1902580 46 0.018
Rat
regulation of protein binding GO:0043393 3 0.018
regulation of anatomical structure morphogenesis GO:0022603 130 0.018
Rat
organelle fusion GO:0048284 3 0.018
embryonic skeletal system morphogenesis GO:0048704 93 0.018
positive regulation of catalytic activity GO:0043085 25 0.018
Zebrafish
positive regulation of signal transduction GO:0009967 56 0.018
Human
positive regulation of cellular extravasation GO:0002693 1 0.017
cell aging GO:0007569 2 0.017
digestive system development GO:0055123 289 0.017
actin filament based movement GO:0030048 1 0.017
sulfur compound biosynthetic process GO:0044272 9 0.017
regulation of nucleotide catabolic process GO:0030811 2 0.017
protein complex disassembly GO:0043241 1 0.017
notochord development GO:0030903 54 0.017
regulation of system process GO:0044057 40 0.017
mesenchymal cell differentiation GO:0048762 87 0.017
establishment of protein localization to organelle GO:0072594 4 0.017
Rat
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.017
carbohydrate derivative metabolic process GO:1901135 61 0.017
negative regulation of neuron projection regeneration GO:0070571 4 0.017
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.017
Human

tnfrsf1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.188
Human
disease of metabolism DOID:0014667 0 0.046
cardiovascular system disease DOID:1287 0 0.035
cancer DOID:162 0 0.029
disease of cellular proliferation DOID:14566 0 0.029
organ system cancer DOID:0050686 0 0.029
musculoskeletal system disease DOID:17 0 0.020
immune system disease DOID:2914 0 0.017