Danio rerio

19 known processes

tnfrsfa

tumor necrosis factor receptor superfamily, member a

(Aliases: OTR,tnf,wu:fc27c09)

tnfrsfa biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell communication GO:0010646 232 0.911
Human
sensory organ development GO:0007423 393 0.881
cellular macromolecule metabolic process GO:0044260 391 0.845
Zebrafish
regulation of signal transduction GO:0009966 225 0.787
Human
defense response GO:0006952 47 0.774
Zebrafish
embryonic organ morphogenesis GO:0048562 274 0.773
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.730
regulation of signaling GO:0023051 235 0.627
Human
signal transduction GO:0007165 455 0.618
Human
apoptotic process GO:0006915 116 0.612
defense response to bacterium GO:0042742 22 0.603
Zebrafish
response to wounding GO:0009611 116 0.603
response to exogenous dsrna GO:0043330 6 0.562
extrinsic apoptotic signaling pathway GO:0097191 3 0.558
Human
generation of neurons GO:0048699 385 0.544
phagocytosis GO:0006909 3 0.539
protein localization to nucleus GO:0034504 3 0.535
skeletal system morphogenesis GO:0048705 102 0.493
ameboidal type cell migration GO:0001667 143 0.475
cell surface receptor signaling pathway GO:0007166 325 0.472
Human
regulation of multicellular organismal process GO:0051239 277 0.465
establishment of localization GO:0051234 244 0.465
secondary metabolic process GO:0019748 3 0.456
regulation of transcription dna templated GO:0006355 213 0.450
response to stress GO:0006950 263 0.442
Human Zebrafish
immune response GO:0006955 28 0.436
Zebrafish
regionalization GO:0003002 274 0.429
regulation of peptidase activity GO:0052547 23 0.427
Zebrafish
retina development in camera type eye GO:0060041 146 0.416
negative regulation of cell communication GO:0010648 96 0.413
negative regulation of biological process GO:0048519 304 0.413
head development GO:0060322 303 0.409
mechanosensory lateral line system development GO:0048881 49 0.408
blood vessel morphogenesis GO:0048514 216 0.405
regulation of cell death GO:0010941 103 0.393
blood vessel development GO:0001568 246 0.392
positive regulation of signaling GO:0023056 56 0.386
Human
cell motility GO:0048870 244 0.379
central nervous system development GO:0007417 387 0.374
gene expression GO:0010467 252 0.367
regulation of programmed cell death GO:0043067 101 0.354
regulation of nitrogen compound metabolic process GO:0051171 251 0.352
regulation of cell development GO:0060284 100 0.349
regulation of metabolic process GO:0019222 359 0.348
Zebrafish
organic cyclic compound biosynthetic process GO:1901362 223 0.347
immune system process GO:0002376 241 0.336
Zebrafish
cellular aromatic compound metabolic process GO:0006725 295 0.334
cell migration GO:0016477 237 0.334
regulation of stem cell proliferation GO:0072091 2 0.333
sensory organ morphogenesis GO:0090596 200 0.331
heterocycle metabolic process GO:0046483 290 0.327
embryonic organ development GO:0048568 381 0.324
organic cyclic compound metabolic process GO:1901360 301 0.322
camera type eye development GO:0043010 222 0.322
positive regulation of macromolecule metabolic process GO:0010604 93 0.315
Zebrafish
programmed cell death GO:0012501 119 0.297
organic acid metabolic process GO:0006082 31 0.296
wound healing GO:0042060 90 0.282
negative regulation of cellular process GO:0048523 283 0.279
localization of cell GO:0051674 244 0.278
negative regulation of protein kinase b signaling GO:0051898 2 0.277
posterior lateral line development GO:0048916 38 0.270
cellular protein metabolic process GO:0044267 129 0.267
Zebrafish
neuron development GO:0048666 262 0.266
negative regulation of response to stimulus GO:0048585 104 0.262
cellular component movement GO:0006928 335 0.259
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.259
response to organic substance GO:0010033 153 0.255
immune system development GO:0002520 191 0.252
regulation of multicellular organismal development GO:2000026 223 0.247
regulation of nucleic acid templated transcription GO:1903506 213 0.241
response to external stimulus GO:0009605 264 0.241
Human Zebrafish
regulation of cellular amino acid metabolic process GO:0006521 0 0.238
stem cell proliferation GO:0072089 4 0.236
gland development GO:0048732 143 0.236
regulation of response to stimulus GO:0048583 269 0.230
Human
melanin metabolic process GO:0006582 2 0.230
regulation of cell differentiation GO:0045595 142 0.229
oxoacid metabolic process GO:0043436 31 0.226
locomotion GO:0040011 313 0.225
apoptotic signaling pathway GO:0097190 23 0.221
Human
protein import GO:0017038 3 0.221
regulation of skeletal muscle tissue development GO:0048641 4 0.221
vasculature development GO:0001944 278 0.219
hematopoietic or lymphoid organ development GO:0048534 191 0.219
response to radiation GO:0009314 51 0.215
cellular macromolecule biosynthetic process GO:0034645 224 0.215
regulation of cysteine type endopeptidase activity GO:2000116 21 0.214
Zebrafish
homeostasis of number of cells GO:0048872 62 0.214
positive regulation of apoptotic signaling pathway GO:2001235 1 0.213
regulation of cellular metabolic process GO:0031323 320 0.213
Zebrafish
astrocyte differentiation GO:0048708 1 0.211
carboxylic acid metabolic process GO:0019752 22 0.210
nucleobase containing compound biosynthetic process GO:0034654 205 0.210
response to other organism GO:0051707 97 0.210
Zebrafish
multicellular organism growth GO:0035264 4 0.203
regeneration GO:0031099 91 0.199
regulation of mechanoreceptor differentiation GO:0045631 1 0.195
epidermis development GO:0008544 48 0.193
chemotaxis GO:0006935 104 0.188
central nervous system neuron differentiation GO:0021953 74 0.184
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.184
myeloid cell differentiation GO:0030099 86 0.180
regulation of protein import into nucleus GO:0042306 2 0.180
tissue regeneration GO:0042246 74 0.180
amine metabolic process GO:0009308 2 0.180
negative regulation of signaling GO:0023057 96 0.180
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.179
axonogenesis GO:0007409 152 0.178
response to arsenic containing substance GO:0046685 5 0.178
cellular component assembly GO:0022607 170 0.177
regulation of inner ear receptor cell differentiation GO:2000980 1 0.176
striated muscle tissue development GO:0014706 110 0.173
negative regulation of cyclic nucleotide biosynthetic process GO:0030803 7 0.171
cellular component biogenesis GO:0044085 178 0.169
regulation of apoptotic process GO:0042981 98 0.168
single organism nuclear import GO:1902593 3 0.168
regulation of anatomical structure morphogenesis GO:0022603 130 0.167
wnt signaling pathway GO:0016055 80 0.165
regulation of molecular function GO:0065009 70 0.165
Zebrafish
aging GO:0007568 2 0.165
taxis GO:0042330 109 0.164
larval development GO:0002164 2 0.163
response to biotic stimulus GO:0009607 97 0.163
Zebrafish
regulation of cellular biosynthetic process GO:0031326 245 0.162
eye development GO:0001654 277 0.161
macromolecule biosynthetic process GO:0009059 227 0.161
response to endogenous stimulus GO:0009719 83 0.161
response to chemical GO:0042221 320 0.159
cellular nitrogen compound metabolic process GO:0034641 290 0.157
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.155
cellular component morphogenesis GO:0032989 336 0.155
cellular ketone metabolic process GO:0042180 11 0.154
establishment of protein localization to organelle GO:0072594 4 0.150
regulation of multicellular organism growth GO:0040014 4 0.150
cellular protein modification process GO:0006464 100 0.149
regulation of proteolysis GO:0030162 24 0.148
Zebrafish
cellular response to chemical stimulus GO:0070887 157 0.148
regulation of macromolecule biosynthetic process GO:0010556 225 0.145
sensory perception GO:0007600 39 0.141
liver development GO:0001889 96 0.139
positive regulation of programmed cell death GO:0043068 29 0.135
death GO:0016265 121 0.134
heart development GO:0007507 313 0.134
transport GO:0006810 220 0.133
leukocyte differentiation GO:0002521 25 0.133
neurological system process GO:0050877 62 0.130
regulation of cellular amine metabolic process GO:0033238 0 0.130
protein modification process GO:0036211 100 0.130
actin filament based process GO:0030029 64 0.129
cellular amine metabolic process GO:0044106 2 0.128
positive regulation of cellular process GO:0048522 201 0.128
regulation of cellular protein metabolic process GO:0032268 52 0.128
Zebrafish
regulation of nervous system development GO:0051960 90 0.127
regulation of gene expression GO:0010468 265 0.127
rna biosynthetic process GO:0032774 181 0.126
regulation of cellular ketone metabolic process GO:0010565 7 0.126
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.125
Zebrafish
neuron projection guidance GO:0097485 86 0.125
regulation of rna biosynthetic process GO:2001141 213 0.125
defense response to other organism GO:0098542 33 0.124
Zebrafish
inner ear development GO:0048839 126 0.124
regulation of macromolecule metabolic process GO:0060255 317 0.117
Zebrafish
cell fate specification GO:0001708 68 0.116
dorsal ventral pattern formation GO:0009953 125 0.115
negative regulation of cyclase activity GO:0031280 6 0.114
growth GO:0040007 174 0.114
response to lipid GO:0033993 60 0.114
regulation of synapse assembly GO:0051963 3 0.113
regulation of apoptotic signaling pathway GO:2001233 12 0.113
regulation of synapse organization GO:0050807 3 0.112
positive regulation of biological process GO:0048518 253 0.109
negative regulation of signal transduction GO:0009968 94 0.108
regulation of cell morphogenesis GO:0022604 42 0.108
entrainment of circadian clock GO:0009649 2 0.107
phosphorylation GO:0016310 69 0.104
lateral line development GO:0048882 66 0.104
regulation of catalytic activity GO:0050790 55 0.103
Zebrafish
mechanoreceptor differentiation GO:0042490 37 0.102
muscle tissue development GO:0060537 110 0.100
transcription from rna polymerase ii promoter GO:0006366 80 0.100
positive regulation of gene expression GO:0010628 71 0.100
negative regulation of multicellular organismal process GO:0051241 69 0.099
membrane organization GO:0061024 21 0.099
response to organic cyclic compound GO:0014070 51 0.099
embryonic skeletal system development GO:0048706 97 0.099
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.098
positive regulation of cellular metabolic process GO:0031325 94 0.098
Zebrafish
protein import into nucleus GO:0006606 3 0.097
embryonic skeletal system morphogenesis GO:0048704 93 0.097
hair cell differentiation GO:0035315 32 0.097
response to nutrient GO:0007584 3 0.096
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.096
cellular response to retinoic acid GO:0071300 1 0.095
regulation of neurogenesis GO:0050767 87 0.094
skeletal system development GO:0001501 181 0.093
system process GO:0003008 185 0.093
posterior lateral line system development GO:0048915 46 0.093
negative regulation of purine nucleotide biosynthetic process GO:1900372 7 0.092
axon development GO:0061564 166 0.092
positive regulation of transcription dna templated GO:0045893 57 0.092
peripheral nervous system development GO:0007422 55 0.092
regulation of growth GO:0040008 42 0.091
nucleic acid templated transcription GO:0097659 181 0.091
rna metabolic process GO:0016070 219 0.091
regulation of response to stress GO:0080134 36 0.091
determination of bilateral symmetry GO:0009855 204 0.091
ear development GO:0043583 127 0.090
morphogenesis of an epithelium GO:0002009 333 0.090
positive regulation of signal transduction GO:0009967 56 0.090
Human
regulation of neuron projection development GO:0010975 40 0.089
negative regulation of cyclic nucleotide metabolic process GO:0030800 7 0.089
cellular response to organic substance GO:0071310 105 0.088
transcription dna templated GO:0006351 181 0.088
positive regulation of rna metabolic process GO:0051254 59 0.088
cell morphogenesis GO:0000902 289 0.088
forebrain development GO:0030900 96 0.088
peripheral nervous system neuron differentiation GO:0048934 28 0.087
digestive system development GO:0055123 289 0.087
intracellular signal transduction GO:0035556 85 0.086
Human
small molecule metabolic process GO:0044281 77 0.085
striated muscle cell differentiation GO:0051146 129 0.084
brain development GO:0007420 293 0.083
nucleobase containing compound metabolic process GO:0006139 274 0.083
heterocycle biosynthetic process GO:0018130 215 0.082
specification of symmetry GO:0009799 204 0.082
i kappab kinase nf kappab signaling GO:0007249 4 0.081
Human
cellular nitrogen compound biosynthetic process GO:0044271 218 0.081
regulation of endopeptidase activity GO:0052548 23 0.081
Zebrafish
mitochondrion organization GO:0007005 4 0.081
response to hormone GO:0009725 48 0.080
negative regulation of cell death GO:0060548 60 0.079
embryonic cranial skeleton morphogenesis GO:0048701 90 0.079
single organism localization GO:1902578 225 0.078
positive regulation of apoptotic process GO:0043065 29 0.078
regulation of rna metabolic process GO:0051252 224 0.077
tube morphogenesis GO:0035239 349 0.077
heart morphogenesis GO:0003007 156 0.076
regulation of neuron differentiation GO:0045664 56 0.075
regulation of cell projection organization GO:0031344 44 0.075
negative regulation of lyase activity GO:0051350 6 0.075
cell death GO:0008219 121 0.074
organic substance biosynthetic process GO:1901576 289 0.073
neuron differentiation GO:0030182 353 0.073
response to external biotic stimulus GO:0043207 97 0.073
Zebrafish
camera type eye morphogenesis GO:0048593 108 0.072
regulation of biosynthetic process GO:0009889 250 0.072
chordate embryonic development GO:0043009 271 0.071
phosphorus metabolic process GO:0006793 109 0.070
endodermal cell fate determination GO:0007493 2 0.069
nitrogen compound metabolic process GO:0006807 319 0.068
positive regulation of response to wounding GO:1903036 5 0.068
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.068
embryo development ending in birth or egg hatching GO:0009792 271 0.067
lymphatic endothelial cell differentiation GO:0060836 1 0.067
determination of heart left right asymmetry GO:0061371 117 0.066
cytokinesis GO:0000910 3 0.066
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.065
positive regulation of cellular amine metabolic process GO:0033240 0 0.065
regulation of protein localization to nucleus GO:1900180 2 0.065
response to alkaloid GO:0043279 2 0.064
regulation of cellular component organization GO:0051128 86 0.064
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.064
positive regulation of rna biosynthetic process GO:1902680 57 0.063
single organism organelle organization GO:1902589 199 0.063
homeostatic process GO:0042592 142 0.062
regulation of jak stat cascade GO:0046425 3 0.062
signal transduction in absence of ligand GO:0038034 1 0.062
response to glucocorticoid GO:0051384 1 0.061
cellular amino acid metabolic process GO:0006520 7 0.061
skeletal muscle tissue development GO:0007519 67 0.061
response to abiotic stimulus GO:0009628 122 0.061
Human
macromolecule modification GO:0043412 111 0.061
axon guidance GO:0007411 86 0.061
response to bacterium GO:0009617 58 0.061
Zebrafish
positive regulation of metabolic process GO:0009893 108 0.060
Zebrafish
neuron projection development GO:0031175 180 0.060
protein localization GO:0008104 40 0.060
muscle structure development GO:0061061 196 0.059
cell part morphogenesis GO:0032990 246 0.059
regulation of circadian rhythm GO:0042752 4 0.059
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.059
neuromast development GO:0048884 46 0.057
regulation of stem cell differentiation GO:2000736 4 0.056
response to nitrogen compound GO:1901698 19 0.055
hepaticobiliary system development GO:0061008 98 0.054
positive regulation of cell cycle GO:0045787 3 0.054
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.054
mapk cascade GO:0000165 18 0.054
circadian rhythm GO:0007623 19 0.053
cellular response to endogenous stimulus GO:0071495 68 0.053
cytoskeleton organization GO:0007010 96 0.053
synaptic growth at neuromuscular junction GO:0051124 2 0.053
digestive tract morphogenesis GO:0048546 231 0.052
regulation of protein targeting GO:1903533 2 0.052
negative regulation of innate immune response GO:0045824 2 0.052
regulation of primary metabolic process GO:0080090 311 0.052
Zebrafish
negative regulation of nucleotide biosynthetic process GO:0030809 7 0.051
negative regulation of apoptotic process GO:0043066 55 0.051
single organism transport GO:0044765 206 0.051
rhythmic process GO:0048511 21 0.051
negative regulation of camp metabolic process GO:0030815 7 0.050
eye morphogenesis GO:0048592 144 0.050
lateral line system development GO:0048925 76 0.049
cellular component assembly involved in morphogenesis GO:0010927 107 0.049
negative regulation of developmental process GO:0051093 65 0.048
negative regulation of response to cytokine stimulus GO:0060761 2 0.048
cardiac conduction system development GO:0003161 1 0.048
phosphate containing compound metabolic process GO:0006796 108 0.047
neuromuscular synaptic transmission GO:0007274 2 0.047
regulation of canonical wnt signaling pathway GO:0060828 34 0.047
neuron cellular homeostasis GO:0070050 3 0.047
proteolysis GO:0006508 38 0.047
Zebrafish
nucleic acid metabolic process GO:0090304 244 0.046
regulation of inflammatory response GO:0050727 2 0.046
cellular biosynthetic process GO:0044249 286 0.046
neuroblast proliferation GO:0007405 2 0.046
nuclear transport GO:0051169 4 0.046
nucleocytoplasmic transport GO:0006913 4 0.046
epithelial tube morphogenesis GO:0060562 148 0.046
carbohydrate metabolic process GO:0005975 12 0.046
aromatic compound biosynthetic process GO:0019438 217 0.046
activation of mapk activity GO:0000187 3 0.046
organelle organization GO:0006996 227 0.046
muscle cell development GO:0055001 115 0.045
cellular protein catabolic process GO:0044257 4 0.045
regulation of protein metabolic process GO:0051246 56 0.045
Zebrafish
embryonic heart tube development GO:0035050 133 0.044
cartilage development GO:0051216 96 0.044
membrane invagination GO:0010324 1 0.044
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.044
establishment of cell polarity GO:0030010 18 0.043
actin cytoskeleton organization GO:0030036 63 0.043
determination of left right symmetry GO:0007368 179 0.043
response to light stimulus GO:0009416 46 0.043
ectodermal placode morphogenesis GO:0071697 32 0.043
inner ear morphogenesis GO:0042472 63 0.043
positive regulation of gliogenesis GO:0014015 2 0.043
positive regulation of cellular component biogenesis GO:0044089 3 0.042
erythrocyte homeostasis GO:0034101 55 0.041
innate immune response GO:0045087 13 0.041
Zebrafish
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.041
gtp catabolic process GO:0006184 2 0.041
signal transduction by phosphorylation GO:0023014 18 0.041
negative regulation of camp biosynthetic process GO:0030818 7 0.040
regulation of neuron migration GO:2001222 2 0.040
striated muscle cell development GO:0055002 108 0.040
response to lipopolysaccharide GO:0032496 13 0.040
cell fate commitment GO:0045165 99 0.040
response to inorganic substance GO:0010035 38 0.040
endocytosis GO:0006897 16 0.040
myotube cell development GO:0014904 35 0.039
pigment metabolic process GO:0042440 12 0.039
positive regulation of protein metabolic process GO:0051247 23 0.039
Zebrafish
nuclear import GO:0051170 3 0.039
negative regulation of protein phosphorylation GO:0001933 4 0.039
positive regulation of cell communication GO:0010647 56 0.039
Human
protein targeting to nucleus GO:0044744 3 0.039
digestive tract development GO:0048565 265 0.039
negative regulation of metabolic process GO:0009892 86 0.038
organelle assembly GO:0070925 110 0.038
pituitary gland development GO:0021983 16 0.038
determination of left right asymmetry in nervous system GO:0035545 4 0.038
neuron projection regeneration GO:0031102 16 0.038
negative regulation of nervous system development GO:0051961 22 0.038
cell projection organization GO:0030030 284 0.037
positive regulation of protein complex assembly GO:0031334 2 0.037
regulation of establishment of protein localization GO:0070201 4 0.037
regulation of developmental process GO:0050793 247 0.037
renal tubule morphogenesis GO:0061333 1 0.037
regulation of circadian sleep wake cycle GO:0042749 1 0.037
cellular response to hormone stimulus GO:0032870 39 0.037
skeletal muscle organ development GO:0060538 78 0.037
cell cell signaling GO:0007267 52 0.037
actomyosin structure organization GO:0031032 53 0.037
response to steroid hormone GO:0048545 35 0.037
development of primary female sexual characteristics GO:0046545 4 0.036
negative regulation of intracellular signal transduction GO:1902532 22 0.036
regulation of cyclic nucleotide metabolic process GO:0030799 15 0.036
response to dsrna GO:0043331 7 0.036
regulation of intracellular signal transduction GO:1902531 57 0.036
Human
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.036
Human
organonitrogen compound metabolic process GO:1901564 74 0.036
cell proliferation GO:0008283 80 0.036
neuron death GO:0070997 21 0.036
lipid catabolic process GO:0016042 4 0.036
single organism metabolic process GO:0044710 217 0.036
cardiac atrium development GO:0003230 4 0.035
cellular carbohydrate metabolic process GO:0044262 4 0.035
cellular response to lipid GO:0071396 39 0.035
cellular response to stress GO:0033554 62 0.035
Human
negative regulation of cell differentiation GO:0045596 46 0.034
regulation of muscle organ development GO:0048634 9 0.034
embryonic heart tube morphogenesis GO:0003143 108 0.034
muscle fiber development GO:0048747 52 0.034
regulation of biological quality GO:0065008 263 0.034
negative regulation of catalytic activity GO:0043086 21 0.033
phagocytosis engulfment GO:0006911 1 0.033
apical protein localization GO:0045176 6 0.033
ear morphogenesis GO:0042471 64 0.033
cell cycle process GO:0022402 53 0.032
cellular response to external stimulus GO:0071496 2 0.032
Human
regulation of heart growth GO:0060420 2 0.032
regulation of striated muscle tissue development GO:0016202 6 0.031
cell projection morphogenesis GO:0048858 244 0.031
glial cell migration GO:0008347 3 0.031
stem cell maintenance GO:0019827 4 0.031
carbohydrate derivative biosynthetic process GO:1901137 43 0.031
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.031
stem cell division GO:0017145 1 0.031
detection of stimulus GO:0051606 29 0.030
sensory perception of pain GO:0019233 1 0.030
positive regulation of stem cell proliferation GO:2000648 1 0.030
artery development GO:0060840 22 0.030
positive regulation of nucleic acid templated transcription GO:1903508 57 0.030
multicellular organism reproduction GO:0032504 35 0.030
cardiac muscle tissue development GO:0048738 48 0.029
positive regulation of nervous system development GO:0051962 25 0.029
muscle cell differentiation GO:0042692 139 0.029
regulation of protein transport GO:0051223 3 0.029
jak stat cascade GO:0007259 5 0.029
positive regulation of cellular biosynthetic process GO:0031328 68 0.029
posterior lateral line neuromast development GO:0048919 20 0.029
long chain fatty acid transport GO:0015909 1 0.029
neuron projection morphogenesis GO:0048812 161 0.028
positive regulation of intracellular signal transduction GO:1902533 15 0.028
Human
myotube differentiation GO:0014902 45 0.028
hindbrain development GO:0030902 91 0.028
otic vesicle formation GO:0030916 27 0.028
positive regulation of cell death GO:0010942 29 0.028
cell morphogenesis involved in differentiation GO:0000904 195 0.028
guanosine containing compound catabolic process GO:1901069 2 0.028
skeletal muscle cell proliferation GO:0014856 2 0.027
connective tissue development GO:0061448 99 0.027
regulation of localization GO:0032879 104 0.027
cranial nerve morphogenesis GO:0021602 15 0.027
anterior posterior pattern specification GO:0009952 152 0.027
aorta morphogenesis GO:0035909 3 0.027
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.027
regulation of phosphorus metabolic process GO:0051174 43 0.027
positive regulation of transport GO:0051050 2 0.027
heart contraction GO:0060047 71 0.026
positive regulation of jak stat cascade GO:0046427 2 0.026
negative regulation of wnt signaling pathway GO:0030178 30 0.026
regulation of protein kinase b signaling GO:0051896 8 0.026
protein phosphorylation GO:0006468 47 0.026
muscle organ development GO:0007517 101 0.026
response to corticosteroid GO:0031960 1 0.026
epithelium regeneration GO:1990399 14 0.026
establishment of localization in cell GO:0051649 77 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.026
organ regeneration GO:0031100 1 0.026
extraocular skeletal muscle development GO:0002074 3 0.026
negative regulation of cellular metabolic process GO:0031324 77 0.026
detection of external stimulus GO:0009581 24 0.025
developmental maturation GO:0021700 34 0.025
positive regulation of multicellular organismal process GO:0051240 52 0.025
regulation of cellular component movement GO:0051270 55 0.025
blood circulation GO:0008015 87 0.025
guanosine containing compound metabolic process GO:1901068 4 0.025
single organism cellular localization GO:1902580 46 0.025
regulation of cell migration GO:0030334 40 0.025
positive regulation of proteolysis GO:0045862 10 0.025
Zebrafish
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.025
establishment of spindle localization GO:0051293 12 0.025
regulation of wound healing GO:0061041 2 0.025
positive regulation of cysteine type endopeptidase activity GO:2001056 10 0.024
Zebrafish
organic hydroxy compound metabolic process GO:1901615 16 0.024
negative regulation of nucleotide metabolic process GO:0045980 7 0.024
cell cycle GO:0007049 93 0.024
skeletal muscle fiber development GO:0048741 35 0.024
developmental growth GO:0048589 166 0.024
nephron epithelium morphogenesis GO:0072088 1 0.024
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.023
Human
vesicle mediated transport GO:0016192 22 0.023
mesenchyme development GO:0060485 127 0.023
otic vesicle morphogenesis GO:0071600 34 0.023
compound eye development GO:0048749 2 0.023
germ cell development GO:0007281 22 0.023
heart looping GO:0001947 94 0.023
negative regulation of neurogenesis GO:0050768 20 0.023
neural tube development GO:0021915 62 0.023
myofibril assembly GO:0030239 48 0.022
regulation of cell cycle GO:0051726 52 0.022
regulation of axon regeneration GO:0048679 7 0.022
regulation of phosphate metabolic process GO:0019220 43 0.022
response to metal ion GO:0010038 34 0.022
muscle cell migration GO:0014812 4 0.022

tnfrsfa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.288
cardiovascular system disease DOID:1287 0 0.052
auditory system disease DOID:2742 0 0.044
nonsyndromic deafness DOID:0050563 0 0.044
sensory system disease DOID:0050155 0 0.044
nervous system disease DOID:863 0 0.044
musculoskeletal system disease DOID:17 0 0.038
connective tissue disease DOID:65 0 0.038
bone development disease DOID:0080006 0 0.024
bone disease DOID:0080001 0 0.024
muscular disease DOID:0080000 0 0.022