Danio rerio

3 known processes

tnnc2

troponin C type 2 (fast)

(Aliases: wu:fb39a12,fb39a12,tnnc)

tnnc2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
striated muscle cell differentiation GO:0051146 129 0.767
muscle cell development GO:0055001 115 0.758
ventricular cardiac myofibril assembly GO:0055005 4 0.751
cellular component assembly involved in morphogenesis GO:0010927 107 0.573
muscle structure development GO:0061061 196 0.561
cellular component morphogenesis GO:0032989 336 0.515
heart morphogenesis GO:0003007 156 0.475
muscle tissue development GO:0060537 110 0.452
striated muscle cell development GO:0055002 108 0.416
actin filament based process GO:0030029 64 0.404
actomyosin structure organization GO:0031032 53 0.398
cytoskeleton dependent cytokinesis GO:0061640 3 0.383
skeletal muscle thin filament assembly GO:0030240 4 0.381
myofibril assembly GO:0030239 48 0.381
ventricular cardiac muscle cell differentiation GO:0055012 6 0.357
muscle system process GO:0003012 20 0.356
Human Zebrafish
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.322
striated muscle tissue development GO:0014706 110 0.314
heart development GO:0007507 313 0.306
Zebrafish
skeletal myofibril assembly GO:0014866 7 0.296
organelle assembly GO:0070925 110 0.292
single organism organelle organization GO:1902589 199 0.282
heart contraction GO:0060047 71 0.260
Zebrafish
positive regulation of nucleoside metabolic process GO:0045979 1 0.259
fatty acid catabolic process GO:0009062 1 0.234
reactive nitrogen species metabolic process GO:2001057 0 0.233
cardiac muscle cell differentiation GO:0055007 30 0.213
ion transmembrane transport GO:0034220 91 0.201
muscle cell differentiation GO:0042692 139 0.199
atrial cardiac myofibril assembly GO:0055004 2 0.198
positive regulation of blood circulation GO:1903524 2 0.193
larval development GO:0002164 2 0.192
ventricular cardiac muscle cell development GO:0055015 5 0.191
cellular component biogenesis GO:0044085 178 0.182
cellular component assembly GO:0022607 170 0.176
cytokinesis GO:0000910 3 0.169
regulation of heart contraction GO:0008016 32 0.154
heart process GO:0003015 71 0.151
Zebrafish
ventricular cardiac muscle tissue development GO:0003229 3 0.138
cardiac muscle cell development GO:0055013 20 0.137
muscle organ development GO:0007517 101 0.129
adult behavior GO:0030534 2 0.125
cardiac cell development GO:0055006 21 0.122
cardiac myofibril assembly GO:0055003 9 0.121
sarcomere organization GO:0045214 26 0.120
atp catabolic process GO:0006200 4 0.119
musculoskeletal movement GO:0050881 8 0.118
Human
transmembrane transport GO:0055085 120 0.117
lymphoid lineage cell migration GO:0097534 4 0.115
cellular aromatic compound metabolic process GO:0006725 295 0.114
reactive oxygen species biosynthetic process GO:1903409 1 0.109
actin cytoskeleton organization GO:0030036 63 0.108
oocyte anterior posterior axis specification GO:0007314 4 0.107
purine nucleoside monophosphate catabolic process GO:0009128 4 0.106
negative regulation of cellular process GO:0048523 283 0.106
regulation of cellular metabolic process GO:0031323 320 0.106
regulation of protein complex assembly GO:0043254 3 0.103
protein polymerization GO:0051258 4 0.102
cardiac muscle tissue development GO:0048738 48 0.102
regulation of muscle contraction GO:0006937 3 0.098
negative regulation of biological process GO:0048519 304 0.098
monocarboxylic acid catabolic process GO:0072329 3 0.097
positive regulation of heart contraction GO:0045823 2 0.093
pole plasm assembly GO:0007315 4 0.093
regulation of macromolecule biosynthetic process GO:0010556 225 0.092
regulation of purine nucleotide catabolic process GO:0033121 2 0.092
nitrogen compound metabolic process GO:0006807 319 0.089
tube morphogenesis GO:0035239 349 0.088
striated muscle contraction GO:0006941 12 0.088
Human Zebrafish
organic substance biosynthetic process GO:1901576 289 0.086
nucleoside monophosphate catabolic process GO:0009125 4 0.086
embryonic heart tube development GO:0035050 133 0.086
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.085
system process GO:0003008 185 0.083
Human Zebrafish
regulation of nucleoside metabolic process GO:0009118 2 0.082
regulation of protein polymerization GO:0032271 2 0.081
lipid catabolic process GO:0016042 4 0.080
purine ribonucleoside triphosphate biosynthetic process GO:0009206 2 0.078
regulation of nitric oxide mediated signal transduction GO:0010749 1 0.076
cytoplasm organization GO:0007028 4 0.075
regulation of transmembrane transporter activity GO:0022898 2 0.075
cardiac muscle tissue morphogenesis GO:0055008 7 0.074
organic acid catabolic process GO:0016054 3 0.073
muscle contraction GO:0006936 18 0.071
Human Zebrafish
cellular amino acid biosynthetic process GO:0008652 2 0.070
regulation of blood circulation GO:1903522 32 0.070
lymphoid lineage cell migration into thymus GO:0097535 4 0.070
organelle organization GO:0006996 227 0.070
maintenance of location GO:0051235 4 0.069
mitotic cytokinesis GO:0000281 3 0.069
regulation of multicellular organismal process GO:0051239 277 0.069
cell projection morphogenesis GO:0048858 244 0.069
reactive oxygen species metabolic process GO:0072593 6 0.069
pronephros development GO:0048793 69 0.069
regulation of system process GO:0044057 40 0.068
neuron development GO:0048666 262 0.067
regulation of systemic arterial blood pressure GO:0003073 1 0.065
determination of heart left right asymmetry GO:0061371 117 0.064
small molecule catabolic process GO:0044282 3 0.063
aging GO:0007568 2 0.062
cardiac ventricle morphogenesis GO:0003208 7 0.062
heart looping GO:0001947 94 0.061
kidney development GO:0001822 92 0.061
cardiocyte differentiation GO:0035051 44 0.061
cell part morphogenesis GO:0032990 246 0.060
regulation of ion transmembrane transporter activity GO:0032412 2 0.059
morphogenesis of an epithelium GO:0002009 333 0.059
cellular modified amino acid metabolic process GO:0006575 3 0.058
ribonucleoside monophosphate catabolic process GO:0009158 4 0.058
maternal determination of anterior posterior axis embryo GO:0008358 4 0.056
nitric oxide biosynthetic process GO:0006809 2 0.055
myosin filament organization GO:0031033 6 0.055
circulatory system process GO:0003013 87 0.054
Zebrafish
fatty acid beta oxidation GO:0006635 1 0.054
regulation of nucleotide catabolic process GO:0030811 2 0.054
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.050
intracellular mrna localization GO:0008298 1 0.048
nucleoside biosynthetic process GO:0009163 2 0.047
positive regulation of biological process GO:0048518 253 0.047
rna localization GO:0006403 4 0.046
regulation of metal ion transport GO:0010959 4 0.046
cardiac ventricle development GO:0003231 9 0.046
Zebrafish
cytoskeleton organization GO:0007010 96 0.046
endocardial cushion formation GO:0003272 2 0.045
cardiac chamber morphogenesis GO:0003206 12 0.045
regulation of striated muscle contraction GO:0006942 2 0.044
regulation of purine nucleotide metabolic process GO:1900542 17 0.044
heterocycle metabolic process GO:0046483 290 0.044
positive regulation of cellular biosynthetic process GO:0031328 68 0.044
neuron projection development GO:0031175 180 0.043
endocardial cushion morphogenesis GO:0003203 3 0.043
actin filament based movement GO:0030048 1 0.042
positive regulation of transport GO:0051050 2 0.042
cellular component movement GO:0006928 335 0.042
sequestering of calcium ion GO:0051208 3 0.041
muscle fiber development GO:0048747 52 0.040
epithelial tube morphogenesis GO:0060562 148 0.040
cellular response to unfolded protein GO:0034620 2 0.040
lipid storage GO:0019915 1 0.040
neuron differentiation GO:0030182 353 0.040
biosynthetic process GO:0009058 294 0.040
regulation of transporter activity GO:0032409 2 0.039
nucleic acid metabolic process GO:0090304 244 0.039
regulation of cell projection assembly GO:0060491 4 0.038
mitochondrion organization GO:0007005 4 0.038
positive regulation of cellular catabolic process GO:0031331 3 0.038
post embryonic organ development GO:0048569 4 0.037
multicellular organismal movement GO:0050879 8 0.037
Human
cellular nitrogen compound metabolic process GO:0034641 290 0.037
muscle organ morphogenesis GO:0048644 8 0.037
organic cyclic compound metabolic process GO:1901360 301 0.037
regulation of sequestering of calcium ion GO:0051282 4 0.036
axon development GO:0061564 166 0.035
er nucleus signaling pathway GO:0006984 2 0.035
response to organic substance GO:0010033 153 0.035
lamellipodium organization GO:0097581 1 0.035
cell projection assembly GO:0030031 64 0.034
single organism biosynthetic process GO:0044711 71 0.034
mesenchyme development GO:0060485 127 0.034
regulation of ion transport GO:0043269 22 0.034
cellular amino acid metabolic process GO:0006520 7 0.033
sequestering of metal ion GO:0051238 3 0.033
actin polymerization or depolymerization GO:0008154 2 0.032
transmission of nerve impulse GO:0019226 19 0.032
embryonic organ development GO:0048568 381 0.032
regulation of reproductive process GO:2000241 4 0.032
regulation of nucleic acid templated transcription GO:1903506 213 0.032
localization of cell GO:0051674 244 0.032
regulation of biological quality GO:0065008 263 0.031
hematopoietic stem cell differentiation GO:0060218 20 0.031
regulation of binding GO:0051098 3 0.031
protein complex disassembly GO:0043241 1 0.031
neuromuscular synaptic transmission GO:0007274 2 0.031
regulation of transmembrane transport GO:0034762 18 0.031
regulation of nitrogen compound metabolic process GO:0051171 251 0.030
aromatic compound biosynthetic process GO:0019438 217 0.030
cell morphogenesis GO:0000902 289 0.030
actin filament polymerization GO:0030041 2 0.030
heterocycle biosynthetic process GO:0018130 215 0.030
phosphorus metabolic process GO:0006793 109 0.030
regulation of protein complex disassembly GO:0043244 1 0.029
nucleoside metabolic process GO:0009116 11 0.029
locomotion GO:0040011 313 0.029
protein complex assembly GO:0006461 30 0.028
renal system development GO:0072001 94 0.028
generation of neurons GO:0048699 385 0.028
signal transduction GO:0007165 455 0.028
regulation of circadian rhythm GO:0042752 4 0.028
embryonic heart tube morphogenesis GO:0003143 108 0.028
centrosome cycle GO:0007098 1 0.028
regulation of calcium ion transport GO:0051924 2 0.028
cellular macromolecule biosynthetic process GO:0034645 224 0.028
nitric oxide metabolic process GO:0046209 2 0.027
protein depolymerization GO:0051261 1 0.027
water homeostasis GO:0030104 4 0.027
guanosine containing compound metabolic process GO:1901068 4 0.027
cellular lipid catabolic process GO:0044242 3 0.027
somatic muscle development GO:0007525 4 0.026
cell projection organization GO:0030030 284 0.026
negative regulation of kinase activity GO:0033673 4 0.026
mechanosensory behavior GO:0007638 2 0.026
cardiac chamber development GO:0003205 19 0.026
Zebrafish
nucleobase containing compound metabolic process GO:0006139 274 0.026
regulation of primary metabolic process GO:0080090 311 0.026
negative regulation of muscle contraction GO:0045932 1 0.026
response to chemical GO:0042221 320 0.025
positive regulation of cellular component biogenesis GO:0044089 3 0.025
single organism localization GO:1902578 225 0.025
cation transport GO:0006812 81 0.024
actin filament organization GO:0007015 15 0.024
dendrite development GO:0016358 9 0.023
calcium ion import GO:0070509 4 0.023
embryo development ending in birth or egg hatching GO:0009792 271 0.023
regulation of membrane potential GO:0042391 23 0.023
atrial cardiac muscle cell differentiation GO:0055011 5 0.023
cell motility GO:0048870 244 0.023
regulation of cell shape GO:0008360 1 0.023
organonitrogen compound metabolic process GO:1901564 74 0.023
small molecule metabolic process GO:0044281 77 0.023
protein metabolic process GO:0019538 183 0.023
metal ion transport GO:0030001 58 0.023
meiotic nuclear division GO:0007126 4 0.023
rna metabolic process GO:0016070 219 0.023
regulation of macromolecule metabolic process GO:0060255 317 0.023
regulation of cell communication GO:0010646 232 0.023
single organism metabolic process GO:0044710 217 0.023
cellular biosynthetic process GO:0044249 286 0.022
atrial cardiac muscle cell development GO:0055014 4 0.022
regulation of localization GO:0032879 104 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.022
carboxylic acid catabolic process GO:0046395 3 0.022
regulation of cellular biosynthetic process GO:0031326 245 0.022
cellular response to topologically incorrect protein GO:0035967 2 0.021
response to unfolded protein GO:0006986 2 0.021
ribose phosphate metabolic process GO:0019693 27 0.021
regulation of cardiac muscle contraction GO:0055117 2 0.021
protein localization to nucleus GO:0034504 3 0.021
nucleobase containing compound biosynthetic process GO:0034654 205 0.021
cytosolic calcium ion transport GO:0060401 3 0.020
homeostatic process GO:0042592 142 0.020
circadian sleep wake cycle process GO:0022410 2 0.020
regulation of multicellular organismal development GO:2000026 223 0.020
myotube cell development GO:0014904 35 0.020
behavior GO:0007610 74 0.019
circadian sleep wake cycle GO:0042745 2 0.019
striated muscle myosin thick filament assembly GO:0071688 6 0.019
cell migration GO:0016477 237 0.019
regionalization GO:0003002 274 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.019
oxoacid metabolic process GO:0043436 31 0.019
venous blood vessel morphogenesis GO:0048845 3 0.019
ribonucleotide metabolic process GO:0009259 27 0.019
regulation of cellular component size GO:0032535 30 0.018
urogenital system development GO:0001655 97 0.018
ion transport GO:0006811 114 0.018
cellular nitrogen compound biosynthetic process GO:0044271 218 0.018
blood circulation GO:0008015 87 0.018
Zebrafish
central nervous system development GO:0007417 387 0.018
skeletal muscle fiber development GO:0048741 35 0.018
regulation of metabolic process GO:0019222 359 0.018
intracellular signal transduction GO:0035556 85 0.018
immune system process GO:0002376 241 0.017
regulation of response to cytokine stimulus GO:0060759 3 0.017
neuron projection morphogenesis GO:0048812 161 0.017
sleep GO:0030431 1 0.017
cellular response to organic substance GO:0071310 105 0.017
multicellular organismal signaling GO:0035637 22 0.017
regulation of cellular amine metabolic process GO:0033238 0 0.017
establishment of localization GO:0051234 244 0.017
cell division GO:0051301 20 0.017
regulation of biosynthetic process GO:0009889 250 0.016
proteasomal protein catabolic process GO:0010498 2 0.016
cell morphogenesis involved in differentiation GO:0000904 195 0.016
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.016
homeostasis of number of cells GO:0048872 62 0.016
endoplasmic reticulum unfolded protein response GO:0030968 2 0.016
regulation of protein import into nucleus GO:0042306 2 0.016
positive regulation of cellular process GO:0048522 201 0.016
myotube differentiation GO:0014902 45 0.016
transport GO:0006810 220 0.016
fatty acid oxidation GO:0019395 1 0.016
negative regulation of cellular biosynthetic process GO:0031327 55 0.016
determination of bilateral symmetry GO:0009855 204 0.016
sensory organ development GO:0007423 393 0.016
protein complex biogenesis GO:0070271 30 0.016
organic acid metabolic process GO:0006082 31 0.015
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.015
positive regulation of multicellular organismal process GO:0051240 52 0.015
astrocyte differentiation GO:0048708 1 0.015
regulation of protein depolymerization GO:1901879 1 0.015
regulation of signal transduction GO:0009966 225 0.015
skeletal muscle contraction GO:0003009 5 0.015
Human
rna biosynthetic process GO:0032774 181 0.015
mitotic cell cycle process GO:1903047 48 0.015
regulation of gene expression GO:0010468 265 0.015
myosin filament assembly GO:0031034 6 0.015
morphogenesis of a branching epithelium GO:0061138 16 0.015
nucleoside triphosphate biosynthetic process GO:0009142 2 0.015
positive regulation of cellular metabolic process GO:0031325 94 0.015
vasculature development GO:0001944 278 0.015
protein complex subunit organization GO:0071822 46 0.015
positive regulation of secretion by cell GO:1903532 1 0.015
muscle cell migration GO:0014812 4 0.015
regulation of blood pressure GO:0008217 1 0.015
regulation of molecular function GO:0065009 70 0.015
mitotic cell cycle GO:0000278 64 0.015
phosphate containing compound metabolic process GO:0006796 108 0.014
protein import GO:0017038 3 0.014
cellular component disassembly GO:0022411 1 0.014
negative regulation of protein phosphorylation GO:0001933 4 0.014
lamellipodium assembly GO:0030032 1 0.014
carbohydrate derivative metabolic process GO:1901135 61 0.014
response to external stimulus GO:0009605 264 0.014
action potential GO:0001508 19 0.014
regulation of cellular component biogenesis GO:0044087 12 0.014
cardiac muscle fiber development GO:0048739 3 0.014
mesenchyme morphogenesis GO:0072132 5 0.014
transcription dna templated GO:0006351 181 0.014
chordate embryonic development GO:0043009 271 0.014
macromolecular complex subunit organization GO:0043933 74 0.013
female sex differentiation GO:0046660 4 0.013
response to external biotic stimulus GO:0043207 97 0.013
skeletal muscle organ development GO:0060538 78 0.013
nucleotide metabolic process GO:0009117 28 0.013
negative regulation of protein kinase activity GO:0006469 4 0.013
neuronal action potential GO:0019228 18 0.013
regulation of myotube differentiation GO:0010830 2 0.013
patterning of blood vessels GO:0001569 15 0.013
amine metabolic process GO:0009308 2 0.013
protein dephosphorylation GO:0006470 3 0.013
macromolecule biosynthetic process GO:0009059 227 0.013
establishment of protein localization to organelle GO:0072594 4 0.013
regulation of stem cell differentiation GO:2000736 4 0.013
regulation of cell development GO:0060284 100 0.013
cardiac muscle contraction GO:0060048 6 0.013
Zebrafish
regulation of stem cell proliferation GO:0072091 2 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
response to drug GO:0042493 3 0.012
regulation of establishment of protein localization GO:0070201 4 0.012
blood vessel development GO:0001568 246 0.012
cellular amine metabolic process GO:0044106 2 0.012
eye development GO:0001654 277 0.012
regulation of response to stimulus GO:0048583 269 0.012
positive regulation of skeletal muscle tissue development GO:0048643 1 0.012
twitch skeletal muscle contraction GO:0014721 4 0.012
cellular macromolecular complex assembly GO:0034622 24 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
regulation of cell projection organization GO:0031344 44 0.012
dopamine metabolic process GO:0042417 2 0.012
cell cycle GO:0007049 93 0.012
protein heterooligomerization GO:0051291 1 0.012
circadian sleep wake cycle sleep GO:0050802 1 0.012
axis specification GO:0009798 43 0.012
regulation of anatomical structure size GO:0090066 33 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.011
organophosphate metabolic process GO:0019637 37 0.011
positive regulation of nucleic acid templated transcription GO:1903508 57 0.011
regulation of protein targeting GO:1903533 2 0.011
sarcomerogenesis GO:0048769 4 0.011
gtp metabolic process GO:0046039 4 0.011
glucose homeostasis GO:0042593 1 0.011
endocardial cushion development GO:0003197 6 0.011
hematopoietic or lymphoid organ development GO:0048534 191 0.011
regulation of synaptic plasticity GO:0048167 1 0.011
regulation of transport GO:0051049 45 0.011
purine nucleotide metabolic process GO:0006163 27 0.011
alternative mrna splicing via spliceosome GO:0000380 1 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
cellular protein complex assembly GO:0043623 19 0.011
inorganic cation transmembrane transport GO:0098662 50 0.011
negative regulation of mapk cascade GO:0043409 4 0.011
carboxylic acid metabolic process GO:0019752 22 0.011
cell growth GO:0016049 57 0.011
regulation of circadian sleep wake cycle GO:0042749 1 0.011
morphogenesis of a branching structure GO:0001763 21 0.011
regulation of protein binding GO:0043393 3 0.010
connective tissue development GO:0061448 99 0.010
organic cyclic compound biosynthetic process GO:1901362 223 0.010
centrosome organization GO:0051297 1 0.010
trabecula formation GO:0060343 2 0.010
single organism nuclear import GO:1902593 3 0.010
nucleic acid templated transcription GO:0097659 181 0.010
regulation of cellular ketone metabolic process GO:0010565 7 0.010
larval behavior GO:0030537 5 0.010

tnnc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 0 0.222
disease of anatomical entity DOID:7 0 0.222
muscular disease DOID:0080000 0 0.222
muscle tissue disease DOID:66 0 0.186
intrinsic cardiomyopathy DOID:0060036 0 0.099
cardiovascular system disease DOID:1287 0 0.099
myopathy DOID:423 0 0.099
heart disease DOID:114 0 0.099
cardiomyopathy DOID:0050700 0 0.099
hypertrophic cardiomyopathy DOID:11984 0 0.099
distal arthrogryposis DOID:0050646 0 0.056