Danio rerio

0 known processes

tpm2

tropomyosin 2 (beta)

(Aliases: wu:fb68h02,fb68h02,tpm4l,zgc:86810,wu:fj63f03,cb836)

tpm2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
myofibril assembly GO:0030239 48 0.432
Zebrafish
actin filament based process GO:0030029 64 0.342
Zebrafish Worm
organelle assembly GO:0070925 110 0.311
Zebrafish
larval development GO:0002164 2 0.284
Worm
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.259
axon development GO:0061564 166 0.254
cardiac muscle cell development GO:0055013 20 0.245
Zebrafish
muscle tissue development GO:0060537 110 0.243
Zebrafish
cell morphogenesis involved in differentiation GO:0000904 195 0.243
muscle cell development GO:0055001 115 0.224
Zebrafish
striated muscle cell development GO:0055002 108 0.213
Zebrafish
cell morphogenesis GO:0000902 289 0.209
heart development GO:0007507 313 0.185
Zebrafish Fly
cytokinesis GO:0000910 3 0.175
Worm
neuron projection morphogenesis GO:0048812 161 0.172
cell projection organization GO:0030030 284 0.139
neuron development GO:0048666 262 0.138
cardiac muscle tissue development GO:0048738 48 0.133
Zebrafish
nucleoside monophosphate catabolic process GO:0009125 4 0.128
Human
cellular component morphogenesis GO:0032989 336 0.128
Zebrafish
circulatory system process GO:0003013 87 0.127
Zebrafish
muscle structure development GO:0061061 196 0.126
Zebrafish
cellular component assembly involved in morphogenesis GO:0010927 107 0.119
Zebrafish
neuron projection development GO:0031175 180 0.119
regulation of gene expression GO:0010468 265 0.112
cytoskeleton dependent cytokinesis GO:0061640 3 0.106
generation of neurons GO:0048699 385 0.105
sarcomere organization GO:0045214 26 0.100
blood circulation GO:0008015 87 0.098
Zebrafish
muscle contraction GO:0006936 18 0.096
Zebrafish
muscle organ development GO:0007517 101 0.095
skeletal muscle organ development GO:0060538 78 0.091
neuron differentiation GO:0030182 353 0.089
regulation of metal ion transport GO:0010959 4 0.086
actomyosin structure organization GO:0031032 53 0.084
Zebrafish
cytoskeleton organization GO:0007010 96 0.081
Zebrafish Worm
embryo development ending in birth or egg hatching GO:0009792 271 0.078
Worm
multi organism process GO:0051704 134 0.077
Worm
skeletal muscle tissue development GO:0007519 67 0.073
system process GO:0003008 185 0.073
Zebrafish
directional locomotion GO:0033058 1 0.073
regulation of nucleoside metabolic process GO:0009118 2 0.072
Human
cardiac myofibril assembly GO:0055003 9 0.067
Zebrafish
cellular component assembly GO:0022607 170 0.067
Zebrafish Worm
regulation of mrna splicing via spliceosome GO:0048024 3 0.066
axonogenesis GO:0007409 152 0.065
regulation of macromolecule biosynthetic process GO:0010556 225 0.064
cell cycle process GO:0022402 53 0.061
Worm
cell projection morphogenesis GO:0048858 244 0.060
aging GO:0007568 2 0.059
regionalization GO:0003002 274 0.057
cell part morphogenesis GO:0032990 246 0.056
regulation of muscle contraction GO:0006937 3 0.055
somatic muscle development GO:0007525 4 0.053
maintenance of location GO:0051235 4 0.053
regulation of primary metabolic process GO:0080090 311 0.051
Human
positive regulation of transport GO:0051050 2 0.051
locomotion GO:0040011 313 0.050
Worm
mitochondrion organization GO:0007005 4 0.049
cell migration GO:0016477 237 0.048
muscle cell differentiation GO:0042692 139 0.048
Zebrafish
alternative mrna splicing via spliceosome GO:0000380 1 0.047
cellular component biogenesis GO:0044085 178 0.047
Zebrafish Worm
regulation of biological quality GO:0065008 263 0.046
Worm
spermatid differentiation GO:0048515 2 0.046
neurotransmitter transport GO:0006836 2 0.045
positive regulation of cytokine production GO:0001819 2 0.045
cellular component movement GO:0006928 335 0.045
regulation of cellular metabolic process GO:0031323 320 0.045
Human
regulation of system process GO:0044057 40 0.045
ameboidal type cell migration GO:0001667 143 0.044
cellular macromolecule metabolic process GO:0044260 391 0.044
regulation of developmental process GO:0050793 247 0.044
positive regulation of cell cycle GO:0045787 3 0.043
protein stabilization GO:0050821 2 0.042
neuron recognition GO:0008038 18 0.041
cardiac muscle fiber development GO:0048739 3 0.041
regulation of cell projection assembly GO:0060491 4 0.040
response to biotic stimulus GO:0009607 97 0.039
spermatid development GO:0007286 2 0.039
cognition GO:0050890 1 0.038
striated muscle cell differentiation GO:0051146 129 0.038
Zebrafish
regulation of synapse assembly GO:0051963 3 0.038
regulation of mrna processing GO:0050684 3 0.036
nucleobase containing compound metabolic process GO:0006139 274 0.036
Human
single organism membrane fusion GO:0044801 2 0.035
response to external stimulus GO:0009605 264 0.035
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.034
purine nucleoside monophosphate catabolic process GO:0009128 4 0.034
Human
heart process GO:0003015 71 0.034
Zebrafish
multicellular organism reproduction GO:0032504 35 0.034
Worm
regulation of dendrite development GO:0050773 3 0.034
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.034
transport GO:0006810 220 0.034
synaptic growth at neuromuscular junction GO:0051124 2 0.034
cytokinetic process GO:0032506 2 0.033
cardiac muscle contraction GO:0060048 6 0.033
Zebrafish
cellular nitrogen compound metabolic process GO:0034641 290 0.032
Human
glial cell migration GO:0008347 3 0.032
growth GO:0040007 174 0.032
chordate embryonic development GO:0043009 271 0.032
cytoplasm organization GO:0007028 4 0.032
taxis GO:0042330 109 0.031
anterior posterior pattern specification GO:0009952 152 0.031
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.031
Human
stem cell development GO:0048864 82 0.031
regulation of cellular ketone metabolic process GO:0010565 7 0.031
muscle attachment GO:0016203 9 0.030
regulation of binding GO:0051098 3 0.030
Worm
biosynthetic process GO:0009058 294 0.030
maintenance of epithelial cell apical basal polarity GO:0045199 5 0.030
regulation of cellular component organization GO:0051128 86 0.030
Worm
muscle system process GO:0003012 20 0.030
Zebrafish
cell recognition GO:0008037 19 0.029
inositol lipid mediated signaling GO:0048017 2 0.029
lipid homeostasis GO:0055088 3 0.029
nucleic acid templated transcription GO:0097659 181 0.029
post embryonic morphogenesis GO:0009886 4 0.029
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.029
Human
intracellular mrna localization GO:0008298 1 0.029
aromatic compound biosynthetic process GO:0019438 217 0.029
lamellipodium assembly GO:0030032 1 0.028
actin cytoskeleton organization GO:0030036 63 0.028
Zebrafish Worm
ventricular cardiac muscle tissue development GO:0003229 3 0.028
cellular biosynthetic process GO:0044249 286 0.027
somitogenesis GO:0001756 87 0.027
regulation of cell differentiation GO:0045595 142 0.027
negative regulation of macromolecule metabolic process GO:0010605 76 0.027
neuroblast proliferation GO:0007405 2 0.027
regulation of ion transmembrane transporter activity GO:0032412 2 0.027
rna localization GO:0006403 4 0.027
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.026
circadian sleep wake cycle sleep GO:0050802 1 0.026
regulation of nucleotide catabolic process GO:0030811 2 0.026
Human
heterocycle metabolic process GO:0046483 290 0.026
Human
collagen metabolic process GO:0032963 2 0.025
sequestering of metal ion GO:0051238 3 0.025
single organism organelle organization GO:1902589 199 0.025
Zebrafish Worm
regulation of nitrogen compound metabolic process GO:0051171 251 0.025
Human
mesodermal cell migration GO:0008078 12 0.025
positive regulation of cellular component biogenesis GO:0044089 3 0.025
behavior GO:0007610 74 0.025
Worm
regulation of purine nucleotide catabolic process GO:0033121 2 0.024
Human
long chain fatty acid biosynthetic process GO:0042759 1 0.024
carboxylic acid metabolic process GO:0019752 22 0.024
voluntary skeletal muscle contraction GO:0003010 4 0.024
actin polymerization or depolymerization GO:0008154 2 0.024
Worm
ventricular cardiac myofibril assembly GO:0055005 4 0.024
regulation of biosynthetic process GO:0009889 250 0.023
regulation of cell shape GO:0008360 1 0.023
maternal determination of anterior posterior axis embryo GO:0008358 4 0.023
axonal fasciculation GO:0007413 11 0.023
cardiac muscle cell differentiation GO:0055007 30 0.023
Zebrafish
regulation of localization GO:0032879 104 0.023
gene expression GO:0010467 252 0.023
lipid storage GO:0019915 1 0.023
signal transduction GO:0007165 455 0.023
negative regulation of cellular process GO:0048523 283 0.022
Worm
ventricular cardiac muscle cell differentiation GO:0055012 6 0.022
reproductive process GO:0022414 40 0.022
Worm
nitrogen compound metabolic process GO:0006807 319 0.022
Human
oxoacid metabolic process GO:0043436 31 0.022
regulation of organelle organization GO:0033043 29 0.022
Worm
organic substance biosynthetic process GO:1901576 289 0.022
ion transport GO:0006811 114 0.021
regulation of rna metabolic process GO:0051252 224 0.021
nucleic acid metabolic process GO:0090304 244 0.021
convergent extension involved in gastrulation GO:0060027 71 0.021
fatty acid transport GO:0015908 1 0.021
cellular nitrogen compound biosynthetic process GO:0044271 218 0.021
organic cyclic compound metabolic process GO:1901360 301 0.021
Human
regulation of blood circulation GO:1903522 32 0.020
segmentation GO:0035282 97 0.020
regulation of synapse organization GO:0050807 3 0.020
multi organism reproductive process GO:0044703 36 0.020
Worm
pole plasm assembly GO:0007315 4 0.020
regulation of macromolecule metabolic process GO:0060255 317 0.020
sequestering of calcium ion GO:0051208 3 0.020
oocyte anterior posterior axis specification GO:0007314 4 0.019
mrna metabolic process GO:0016071 20 0.019
fatty acid biosynthetic process GO:0006633 4 0.019
regulation of dendrite morphogenesis GO:0048814 3 0.019
mitotic cell cycle GO:0000278 64 0.019
cellular amine metabolic process GO:0044106 2 0.019
neurotransmitter secretion GO:0007269 2 0.019
regulation of meiotic cell cycle GO:0051445 1 0.018
regulation of transmembrane transporter activity GO:0022898 2 0.018
localization of cell GO:0051674 244 0.018
regulation of cell cycle GO:0051726 52 0.018
organonitrogen compound metabolic process GO:1901564 74 0.018
Human
regulation of circadian rhythm GO:0042752 4 0.018
small molecule metabolic process GO:0044281 77 0.018
Human
multicellular organism growth GO:0035264 4 0.018
membrane fusion GO:0061025 2 0.018
single organism metabolic process GO:0044710 217 0.018
Human
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.018
axis specification GO:0009798 43 0.017
regulation of response to stimulus GO:0048583 269 0.017
cell division GO:0051301 20 0.017
Worm
neuron projection guidance GO:0097485 86 0.017
g1 s transition of mitotic cell cycle GO:0000082 1 0.017
protein metabolic process GO:0019538 183 0.017
circadian sleep wake cycle process GO:0022410 2 0.017
striated muscle contraction GO:0006941 12 0.017
Zebrafish
heart morphogenesis GO:0003007 156 0.017
actin filament based movement GO:0030048 1 0.017
regulation of blood pressure GO:0008217 1 0.017
regulation of heart contraction GO:0008016 32 0.017
long chain fatty acid metabolic process GO:0001676 1 0.017
single organism reproductive process GO:0044702 40 0.017
Worm
long chain fatty acid transport GO:0015909 1 0.017
anatomical structure homeostasis GO:0060249 36 0.017
dorsal ventral pattern formation GO:0009953 125 0.017
amine metabolic process GO:0009308 2 0.017
regulation of striated muscle contraction GO:0006942 2 0.017
rna metabolic process GO:0016070 219 0.017
cellular ketone metabolic process GO:0042180 11 0.016
twitch skeletal muscle contraction GO:0014721 4 0.016
cardiac atrium development GO:0003230 4 0.016
regulation of multicellular organismal process GO:0051239 277 0.016
establishment of protein localization to organelle GO:0072594 4 0.016
macromolecular complex disassembly GO:0032984 1 0.016
Worm
striated muscle tissue development GO:0014706 110 0.016
Zebrafish
anatomical structure arrangement GO:0048532 2 0.016
slow twitch skeletal muscle fiber contraction GO:0031444 3 0.015
cell cycle GO:0007049 93 0.015
Worm
regulation of sequestering of calcium ion GO:0051282 4 0.015
negative regulation of developmental process GO:0051093 65 0.015
cellular component disassembly GO:0022411 1 0.015
Worm
macromolecule modification GO:0043412 111 0.015
regulation of rho protein signal transduction GO:0035023 2 0.015
modification dependent protein catabolic process GO:0019941 3 0.015
protein depolymerization GO:0051261 1 0.015
Worm
nitric oxide biosynthetic process GO:0006809 2 0.015
membrane invagination GO:0010324 1 0.015
rna splicing GO:0008380 16 0.015
negative regulation of biological process GO:0048519 304 0.015
Worm
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.015
reactive oxygen species biosynthetic process GO:1903409 1 0.015
nitric oxide metabolic process GO:0046209 2 0.015
calcium ion transport into cytosol GO:0060402 3 0.015
ubiquitin dependent protein catabolic process GO:0006511 3 0.014
lipid oxidation GO:0034440 1 0.014
regulation of cytokine production GO:0001817 3 0.014
muscle cell cellular homeostasis GO:0046716 5 0.014
ribonucleoside monophosphate catabolic process GO:0009158 4 0.014
Human
regulation of cell activation GO:0050865 1 0.014
regulation of protein complex assembly GO:0043254 3 0.014
Worm
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.014
somite development GO:0061053 96 0.014
meiotic nuclear division GO:0007126 4 0.014
protein localization to plasma membrane GO:0072659 1 0.014
cellular response to starvation GO:0009267 1 0.014
cardiac atrium morphogenesis GO:0003209 2 0.014
cell cycle g1 s phase transition GO:0044843 1 0.014
midbrain development GO:0030901 28 0.014
adult behavior GO:0030534 2 0.014
phagocytosis engulfment GO:0006911 1 0.014
nuclear division GO:0000280 23 0.014
cellular aromatic compound metabolic process GO:0006725 295 0.014
Human
cardiac cell development GO:0055006 21 0.014
Zebrafish
cell surface receptor signaling pathway GO:0007166 325 0.013
negative regulation of protein kinase activity GO:0006469 4 0.013
intracellular signal transduction GO:0035556 85 0.013
negative regulation of protein phosphorylation GO:0001933 4 0.013
locomotor rhythm GO:0045475 3 0.013
oocyte development GO:0048599 14 0.013
establishment of localization GO:0051234 244 0.013
regulation of cytoplasmic transport GO:1903649 4 0.013
developmental programmed cell death GO:0010623 4 0.013
cellular amino acid metabolic process GO:0006520 7 0.013
negative regulation of translation GO:0017148 1 0.013
regulation of calcium ion transport GO:0051924 2 0.013
heterocycle biosynthetic process GO:0018130 215 0.013
multicellular organismal reproductive process GO:0048609 35 0.013
Worm
regulation of cell communication GO:0010646 232 0.013
cell fate commitment GO:0045165 99 0.013
heart contraction GO:0060047 71 0.013
Zebrafish
regulation of multicellular organism growth GO:0040014 4 0.013
catabolic process GO:0009056 32 0.013
Human
regulation of intracellular protein transport GO:0033157 3 0.013
homeostatic process GO:0042592 142 0.013
regulation of signaling GO:0023051 235 0.012
modification dependent macromolecule catabolic process GO:0043632 3 0.012
positive regulation of catabolic process GO:0009896 4 0.012
positive regulation of cellular catabolic process GO:0031331 3 0.012
regulation of organ growth GO:0046620 3 0.012
regulation of synaptic plasticity GO:0048167 1 0.012
germ line stem cell maintenance GO:0030718 2 0.012
protein import GO:0017038 3 0.012
nuclear import GO:0051170 3 0.012
apoptotic process involved in development GO:1902742 2 0.012
response to external biotic stimulus GO:0043207 97 0.012
neurological system process GO:0050877 62 0.012
organic acid metabolic process GO:0006082 31 0.012
monocarboxylic acid metabolic process GO:0032787 17 0.012
phosphorus metabolic process GO:0006793 109 0.012
Human
mitotic cytokinesis GO:0000281 3 0.012
cellular response to extracellular stimulus GO:0031668 2 0.011
3 utr mediated mrna stabilization GO:0070935 3 0.011
mrna stabilization GO:0048255 4 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
skeletal muscle myosin thick filament assembly GO:0030241 5 0.011
neuroblast fate determination GO:0007400 1 0.011
regulation of metabolic process GO:0019222 359 0.011
Human
regulation of protein binding GO:0043393 3 0.011
Worm
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
nucleoside phosphate metabolic process GO:0006753 28 0.011
Human
neuroblast differentiation GO:0014016 1 0.011
blood vessel morphogenesis GO:0048514 216 0.011
chemosensory behavior GO:0007635 1 0.011
lipid catabolic process GO:0016042 4 0.011
regulation of nervous system development GO:0051960 90 0.011
regulation of response to biotic stimulus GO:0002831 2 0.011
regulation of cellular biosynthetic process GO:0031326 245 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.011
phagocytosis GO:0006909 3 0.011
adherens junction organization GO:0034332 4 0.011
proteasomal protein catabolic process GO:0010498 2 0.011
rna biosynthetic process GO:0032774 181 0.011
carbohydrate derivative biosynthetic process GO:1901137 43 0.011
proximal distal pattern formation GO:0009954 1 0.011
regulation of heart growth GO:0060420 2 0.011
epithelial cell morphogenesis GO:0003382 2 0.011
chemotaxis GO:0006935 104 0.011
multi organism cellular process GO:0044764 2 0.011
dna templated transcription elongation GO:0006354 3 0.011
cytosolic calcium ion transport GO:0060401 3 0.011
feeding behavior GO:0007631 5 0.011
sensory organ development GO:0007423 393 0.011
angiogenesis GO:0001525 158 0.011
cell death GO:0008219 121 0.011
cellular macromolecule biosynthetic process GO:0034645 224 0.011
death GO:0016265 121 0.011
nucleocytoplasmic transport GO:0006913 4 0.010
blood vessel development GO:0001568 246 0.010
regulation of immune system process GO:0002682 34 0.010
negative regulation of sequestering of calcium ion GO:0051283 4 0.010
actin filament polymerization GO:0030041 2 0.010
Worm
inorganic cation transmembrane transport GO:0098662 50 0.010
regulation of cellular amino acid metabolic process GO:0006521 0 0.010
complement activation GO:0006956 3 0.010
cellular protein metabolic process GO:0044267 129 0.010
cell motility GO:0048870 244 0.010
small molecule catabolic process GO:0044282 3 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
regulation of locomotion GO:0040012 55 0.010
regulation of organelle assembly GO:1902115 4 0.010
pigmentation GO:0043473 85 0.010
protein complex disassembly GO:0043241 1 0.010
Worm

tpm2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.136
Human
myopathy DOID:423 0 0.090
musculoskeletal system disease DOID:17 0 0.090
Human
muscle tissue disease DOID:66 0 0.090
Human
muscular disease DOID:0080000 0 0.090
Human
cardiovascular system disease DOID:1287 0 0.039
heart disease DOID:114 0 0.022
cardiomyopathy DOID:0050700 0 0.022
intrinsic cardiomyopathy DOID:0060036 0 0.022
hypertrophic cardiomyopathy DOID:11984 0 0.015