Danio rerio

76 known processes

traf6

TNF receptor-associated factor 6

(Aliases: MGC63704,zgc:63704,fi15f02,wu:fi15f02)

traf6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.307
cellular macromolecule biosynthetic process GO:0034645 224 0.218
heterocycle biosynthetic process GO:0018130 215 0.202
regulation of gene expression GO:0010468 265 0.190
nucleic acid metabolic process GO:0090304 244 0.184
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.180
regulation of biosynthetic process GO:0009889 250 0.173
regulation of transcription dna templated GO:0006355 213 0.171
nucleic acid templated transcription GO:0097659 181 0.169
cellular macromolecule metabolic process GO:0044260 391 0.161
aromatic compound biosynthetic process GO:0019438 217 0.160
regulation of nitrogen compound metabolic process GO:0051171 251 0.159
transcription dna templated GO:0006351 181 0.155
rna biosynthetic process GO:0032774 181 0.153
signal transduction GO:0007165 455 0.152
Human Mouse Rat
cellular biosynthetic process GO:0044249 286 0.149
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.144
cellular nitrogen compound metabolic process GO:0034641 290 0.143
regulation of macromolecule biosynthetic process GO:0010556 225 0.141
regulation of cellular metabolic process GO:0031323 320 0.140
nucleobase containing compound metabolic process GO:0006139 274 0.140
biosynthetic process GO:0009058 294 0.128
response to external stimulus GO:0009605 264 0.126
nucleobase containing compound biosynthetic process GO:0034654 205 0.125
nitrogen compound metabolic process GO:0006807 319 0.122
regulation of primary metabolic process GO:0080090 311 0.121
organic cyclic compound metabolic process GO:1901360 301 0.120
cellular aromatic compound metabolic process GO:0006725 295 0.111
cellular response to external stimulus GO:0071496 2 0.110
rna metabolic process GO:0016070 219 0.110
regulation of rna metabolic process GO:0051252 224 0.106
regulation of nucleic acid templated transcription GO:1903506 213 0.103
positive regulation of interferon beta production GO:0032728 1 0.103
gene expression GO:0010467 252 0.103
regulation of metabolic process GO:0019222 359 0.103
cytokinesis GO:0000910 3 0.102
regulation of autophagy GO:0010506 3 0.098
nucleocytoplasmic transport GO:0006913 4 0.096
cellular nitrogen compound biosynthetic process GO:0044271 218 0.090
cellular response to nutrient levels GO:0031669 2 0.087
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.083
Human
establishment of protein localization to organelle GO:0072594 4 0.081
regulation of macromolecule metabolic process GO:0060255 317 0.080
heterocycle metabolic process GO:0046483 290 0.079
positive regulation of transport GO:0051050 2 0.079
positive regulation of biological process GO:0048518 253 0.078
organic cyclic compound biosynthetic process GO:1901362 223 0.077
positive regulation of stress activated mapk cascade GO:0032874 3 0.077
Human
macromolecule biosynthetic process GO:0009059 227 0.074
positive regulation of cellular process GO:0048522 201 0.073
regulation of cytokine production GO:0001817 3 0.071
Human Mouse
regulation of rna biosynthetic process GO:2001141 213 0.070
response to bacterium GO:0009617 58 0.069
extrinsic apoptotic signaling pathway GO:0097191 3 0.067
cellular response to lipopolysaccharide GO:0071222 3 0.067
Human Mouse
generation of neurons GO:0048699 385 0.066
cell surface receptor signaling pathway GO:0007166 325 0.065
Human Mouse Rat
single organism nuclear import GO:1902593 3 0.065
cytoskeleton dependent cytokinesis GO:0061640 3 0.065
aging GO:0007568 2 0.065
i kappab kinase nf kappab signaling GO:0007249 4 0.062
Human Mouse
positive regulation of cellular biosynthetic process GO:0031328 68 0.062
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.061
Human Mouse
apoptotic process GO:0006915 116 0.061
protein import GO:0017038 3 0.061
neuron development GO:0048666 262 0.061
cellular component morphogenesis GO:0032989 336 0.060
transport GO:0006810 220 0.059
Mouse
cellular amide metabolic process GO:0043603 4 0.058
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.057
multicellular organism growth GO:0035264 4 0.057
dorsal ventral pattern formation GO:0009953 125 0.057
regulation of protein transport GO:0051223 3 0.057
Mouse
cell morphogenesis GO:0000902 289 0.056
organonitrogen compound metabolic process GO:1901564 74 0.055
response to stress GO:0006950 263 0.055
organic substance biosynthetic process GO:1901576 289 0.055
cellular response to extracellular stimulus GO:0031668 2 0.055
positive regulation of transcription dna templated GO:0045893 57 0.054
regulation of cellular biosynthetic process GO:0031326 245 0.054
protein targeting to nucleus GO:0044744 3 0.053
regionalization GO:0003002 274 0.053
positive regulation of cytokine production GO:0001819 2 0.053
Human Mouse
nuclear transport GO:0051169 4 0.052
regulation of signaling GO:0023051 235 0.052
Human Mouse
establishment of localization GO:0051234 244 0.051
Mouse
phosphorus metabolic process GO:0006793 109 0.051
Human Rat
response to external biotic stimulus GO:0043207 97 0.051
nuclear import GO:0051170 3 0.051
regulation of multicellular organism growth GO:0040014 4 0.050
regulation of cell communication GO:0010646 232 0.049
Human Mouse
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.049
Human Mouse
blood vessel morphogenesis GO:0048514 216 0.049
regulation of multicellular organismal process GO:0051239 277 0.048
Human Mouse
programmed cell death GO:0012501 119 0.047
maintenance of location GO:0051235 4 0.047
response to nutrient GO:0007584 3 0.047
cellular carbohydrate metabolic process GO:0044262 4 0.047
multi organism process GO:0051704 134 0.047
autophagy GO:0006914 4 0.046
neuron projection morphogenesis GO:0048812 161 0.046
cell morphogenesis involved in differentiation GO:0000904 195 0.045
toll like receptor signaling pathway GO:0002224 4 0.045
mitochondrion organization GO:0007005 4 0.045
cell part morphogenesis GO:0032990 246 0.044
protein import into nucleus GO:0006606 3 0.043
cell projection morphogenesis GO:0048858 244 0.043
cell death GO:0008219 121 0.043
cellular amine metabolic process GO:0044106 2 0.043
response to biotic stimulus GO:0009607 97 0.043
cellular response to starvation GO:0009267 1 0.043
phagocytosis GO:0006909 3 0.043
regulation of metal ion transport GO:0010959 4 0.042
neuron differentiation GO:0030182 353 0.041
antimicrobial humoral response GO:0019730 2 0.041
regulation of production of molecular mediator of immune response GO:0002700 1 0.040
Human Mouse
defense response to other organism GO:0098542 33 0.040
immune system process GO:0002376 241 0.040
response to virus GO:0009615 21 0.040
positive regulation of catabolic process GO:0009896 4 0.039
positive regulation of jnk cascade GO:0046330 3 0.039
Human
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.039
cellular component movement GO:0006928 335 0.039
sensory organ development GO:0007423 393 0.038
gtp metabolic process GO:0046039 4 0.038
intracellular signal transduction GO:0035556 85 0.038
Human Mouse Rat
protein secretion GO:0009306 1 0.037
Mouse
cell cycle GO:0007049 93 0.037
positive regulation of secretion by cell GO:1903532 1 0.037
response to other organism GO:0051707 97 0.037
regulation of response to nutrient levels GO:0032107 1 0.036
regulation of protein ubiquitination GO:0031396 3 0.036
regulation of developmental process GO:0050793 247 0.036
Human
cell projection organization GO:0030030 284 0.036
guanosine containing compound catabolic process GO:1901069 2 0.036
cellular response to stress GO:0033554 62 0.036
Human Rat
membrane fusion GO:0061025 2 0.035
macroautophagy GO:0016236 1 0.035
protein metabolic process GO:0019538 183 0.035
Human Mouse
taxis GO:0042330 109 0.034
positive regulation of cellular catabolic process GO:0031331 3 0.034
oxoacid metabolic process GO:0043436 31 0.034
regulation of immune system process GO:0002682 34 0.034
Human Mouse
regulation of signal transduction GO:0009966 225 0.033
Human Mouse
negative regulation of biological process GO:0048519 304 0.033
Human
response to chemical GO:0042221 320 0.033
Human Mouse Rat
carboxylic acid metabolic process GO:0019752 22 0.033
activation of immune response GO:0002253 9 0.033
Human
regulation of biological quality GO:0065008 263 0.032
Mouse
chemotaxis GO:0006935 104 0.032
regulation of protein localization to nucleus GO:1900180 2 0.032
positive regulation of rna metabolic process GO:0051254 59 0.032
blood vessel development GO:0001568 246 0.032
hemopoiesis GO:0030097 183 0.032
Human Mouse
negative regulation of protein phosphorylation GO:0001933 4 0.032
positive regulation of cellular metabolic process GO:0031325 94 0.032
cellular component assembly GO:0022607 170 0.032
Rat
regulation of cellular amino acid metabolic process GO:0006521 0 0.032
lipid storage GO:0019915 1 0.032
regulation of response to stress GO:0080134 36 0.032
Human
regulation of jak stat cascade GO:0046425 3 0.032
locomotion GO:0040011 313 0.032
tissue remodeling GO:0048771 4 0.031
Mouse
axonogenesis GO:0007409 152 0.031
single organism metabolic process GO:0044710 217 0.031
Human Rat
response to organic substance GO:0010033 153 0.031
Human Mouse Rat
single organism transport GO:0044765 206 0.031
Mouse
embryonic organ development GO:0048568 381 0.031
ubiquitin dependent protein catabolic process GO:0006511 3 0.030
cellular component biogenesis GO:0044085 178 0.030
Rat
positive regulation of response to stimulus GO:0048584 80 0.030
Human Mouse
positive regulation of metabolic process GO:0009893 108 0.030
positive regulation of signaling GO:0023056 56 0.029
Human Mouse
growth GO:0040007 174 0.029
cognition GO:0050890 1 0.028
organelle organization GO:0006996 227 0.028
death GO:0016265 121 0.028
stem cell proliferation GO:0072089 4 0.028
central nervous system development GO:0007417 387 0.028
regulation of nucleotide catabolic process GO:0030811 2 0.028
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.028
morphogenesis of an epithelium GO:0002009 333 0.027
Mouse
mitotic cell cycle GO:0000278 64 0.027
vasculature development GO:0001944 278 0.027
peptidyl serine phosphorylation GO:0018105 1 0.027
amine metabolic process GO:0009308 2 0.026
regulation of protein targeting GO:1903533 2 0.026
cell growth GO:0016049 57 0.026
regulation of organelle assembly GO:1902115 4 0.026
small molecule metabolic process GO:0044281 77 0.026
regulation of nucleoside metabolic process GO:0009118 2 0.026
regulation of cytoplasmic transport GO:1903649 4 0.026
peptidyl serine modification GO:0018209 2 0.026
regulation of nucleocytoplasmic transport GO:0046822 2 0.026
regulation of establishment of protein localization GO:0070201 4 0.026
Mouse
regulation of purine nucleotide catabolic process GO:0033121 2 0.026
axon development GO:0061564 166 0.026
positive regulation of biosynthetic process GO:0009891 68 0.025
cellular ketone metabolic process GO:0042180 11 0.025
cellular response to biotic stimulus GO:0071216 3 0.025
Human Mouse
regulation of response to stimulus GO:0048583 269 0.025
Human Mouse
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.025
regulation of protein import into nucleus GO:0042306 2 0.025
regulation of cellular amine metabolic process GO:0033238 0 0.025
angiogenesis GO:0001525 158 0.025
negative regulation of nuclear division GO:0051784 3 0.025
response to ketone GO:1901654 1 0.025
regulation of intracellular protein transport GO:0033157 3 0.024
carbohydrate derivative biosynthetic process GO:1901137 43 0.024
system process GO:0003008 185 0.024
organic acid metabolic process GO:0006082 31 0.024
regulation of calcium ion transport GO:0051924 2 0.024
protein localization to nucleus GO:0034504 3 0.024
peptide transport GO:0015833 1 0.024
positive regulation of cellular component biogenesis GO:0044089 3 0.024
negative regulation of apoptotic process GO:0043066 55 0.024
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.023
modification dependent protein catabolic process GO:0019941 3 0.023
cellular amino acid metabolic process GO:0006520 7 0.023
regulation of protein catabolic process GO:0042176 1 0.023
regulation of response to extracellular stimulus GO:0032104 1 0.023
heart development GO:0007507 313 0.023
positive regulation of multi organism process GO:0043902 3 0.023
Mouse
mitotic dna integrity checkpoint GO:0044774 4 0.023
regulation of carbohydrate metabolic process GO:0006109 4 0.023
positive regulation of myeloid cell differentiation GO:0045639 2 0.023
Human
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.022
Human
guanosine containing compound metabolic process GO:1901068 4 0.022
homeostatic process GO:0042592 142 0.022
Mouse
regulation of circadian rhythm GO:0042752 4 0.022
female sex differentiation GO:0046660 4 0.022
cell migration GO:0016477 237 0.022
positive regulation of rna biosynthetic process GO:1902680 57 0.022
phosphorylation GO:0016310 69 0.022
Human Rat
gtp catabolic process GO:0006184 2 0.022
phagocytosis engulfment GO:0006911 1 0.022
regulation of cell death GO:0010941 103 0.022
eye development GO:0001654 277 0.022
response to monosaccharide GO:0034284 3 0.022
response to drug GO:0042493 3 0.021
protein complex localization GO:0031503 1 0.021
regulation of protein complex assembly GO:0043254 3 0.021
negative regulation of catabolic process GO:0009895 3 0.021
positive regulation of immune effector process GO:0002699 3 0.021
Human
single organism membrane fusion GO:0044801 2 0.021
immune system development GO:0002520 191 0.021
Human Mouse
cell cycle g1 s phase transition GO:0044843 1 0.021
modification dependent macromolecule catabolic process GO:0043632 3 0.021
cellular protein modification process GO:0006464 100 0.021
Human Mouse
tube morphogenesis GO:0035239 349 0.021
Mouse
developmental growth GO:0048589 166 0.021
cellular protein catabolic process GO:0044257 4 0.021
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.021
erythrocyte differentiation GO:0030218 54 0.021
phosphate containing compound metabolic process GO:0006796 108 0.021
Human Rat
positive regulation of neuron apoptotic process GO:0043525 1 0.021
chordate embryonic development GO:0043009 271 0.021
Mouse
positive regulation of stem cell proliferation GO:2000648 1 0.021
negative regulation of programmed cell death GO:0043069 58 0.020
positive regulation of cellular amine metabolic process GO:0033240 0 0.020
positive regulation of dna metabolic process GO:0051054 1 0.020
negative regulation of mitosis GO:0045839 3 0.020
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.020
Human Mouse
positive regulation of cell cycle GO:0045787 3 0.020
positive regulation of macromolecule metabolic process GO:0010604 93 0.020
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.020
regulation of apoptotic process GO:0042981 98 0.020
wound healing GO:0042060 90 0.020
neuron projection guidance GO:0097485 86 0.020
meiotic nuclear division GO:0007126 4 0.020
regulation of gtpase activity GO:0043087 2 0.020
regulation of cellular protein catabolic process GO:1903362 1 0.020
g1 s transition of mitotic cell cycle GO:0000082 1 0.020
mitotic cell cycle process GO:1903047 48 0.020
enzyme linked receptor protein signaling pathway GO:0007167 106 0.019
response to glucocorticoid GO:0051384 1 0.019
regulation of gtp catabolic process GO:0033124 2 0.019
organelle fusion GO:0048284 3 0.019
positive regulation of signal transduction GO:0009967 56 0.019
Human Mouse
nucleoside monophosphate catabolic process GO:0009125 4 0.019
cellular response to molecule of bacterial origin GO:0071219 3 0.019
Human Mouse
positive regulation of secretion GO:0051047 1 0.019
homeostasis of number of cells GO:0048872 62 0.019
regulation of programmed cell death GO:0043067 101 0.019
alpha amino acid metabolic process GO:1901605 3 0.019
phosphatidylinositol mediated signaling GO:0048015 2 0.019
somatic muscle development GO:0007525 4 0.019
regulation of glucose transport GO:0010827 1 0.019
regulation of cellular component organization GO:0051128 86 0.019
negative regulation of secretion GO:0051048 2 0.019
circulatory system process GO:0003013 87 0.019
regulation of cellular ketone metabolic process GO:0010565 7 0.019
lipid homeostasis GO:0055088 3 0.018
neuron projection development GO:0031175 180 0.018
regulation of cytokine biosynthetic process GO:0042035 1 0.018
Mouse
gastrulation GO:0007369 208 0.018
interferon beta production GO:0032608 1 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.018
positive regulation of cell communication GO:0010647 56 0.018
Human Mouse
b cell activation GO:0042113 2 0.018
protein acetylation GO:0006473 2 0.018
cellular component disassembly GO:0022411 1 0.018
positive regulation of type i interferon production GO:0032481 1 0.018
female gonad development GO:0008585 4 0.018
stem cell maintenance GO:0019827 4 0.017
positive regulation of nucleotide catabolic process GO:0030813 1 0.017
positive regulation of nucleoside metabolic process GO:0045979 1 0.017
positive regulation of gtpase activity GO:0043547 1 0.017
negative regulation of cellular catabolic process GO:0031330 3 0.017
response to carbohydrate GO:0009743 3 0.017
mitotic dna damage checkpoint GO:0044773 4 0.017
neuron neuron synaptic transmission GO:0007270 1 0.017
positive regulation of gtp catabolic process GO:0033126 1 0.017
double strand break repair GO:0006302 3 0.017
cellular response to topologically incorrect protein GO:0035967 2 0.017
synaptic target recognition GO:0008039 1 0.017
negative regulation of metabolic process GO:0009892 86 0.017
Human
mononuclear cell proliferation GO:0032943 1 0.017
Mouse
carbohydrate derivative metabolic process GO:1901135 61 0.017
blood circulation GO:0008015 87 0.017
cellular response to radiation GO:0071478 4 0.017
response to uv GO:0009411 3 0.017
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.017
negative regulation of cellular process GO:0048523 283 0.017
Human
single organism localization GO:1902578 225 0.017
Mouse
membrane invagination GO:0010324 1 0.017
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.017
negative regulation of response to stimulus GO:0048585 104 0.017
cellular protein metabolic process GO:0044267 129 0.017
Human Mouse
defense response to virus GO:0051607 10 0.017
response to hexose GO:0009746 3 0.017
glucose homeostasis GO:0042593 1 0.017
regulation of binding GO:0051098 3 0.017
Human
negative regulation of cell communication GO:0010648 96 0.016
cytokine metabolic process GO:0042107 1 0.016
Mouse
atp catabolic process GO:0006200 4 0.016
response to organic cyclic compound GO:0014070 51 0.016
translational initiation GO:0006413 3 0.016
internal protein amino acid acetylation GO:0006475 2 0.016
reproduction GO:0000003 40 0.016
protein acylation GO:0043543 3 0.016
stem cell division GO:0017145 1 0.016
positive regulation of apoptotic signaling pathway GO:2001235 1 0.016
regulation of defense response GO:0031347 14 0.016
iron ion homeostasis GO:0055072 4 0.016
protein modification process GO:0036211 100 0.016
Human Mouse
regulation of innate immune response GO:0045088 11 0.016
retina development in camera type eye GO:0060041 146 0.016
viral process GO:0016032 1 0.016
peptidyl lysine acetylation GO:0018394 2 0.016
meiotic cell cycle process GO:1903046 3 0.016
hematopoietic or lymphoid organ development GO:0048534 191 0.016
Human Mouse
transcription from rna polymerase ii promoter GO:0006366 80 0.016
Human
organonitrogen compound biosynthetic process GO:1901566 47 0.016
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.016
internal peptidyl lysine acetylation GO:0018393 2 0.016
regulation of inflammatory response GO:0050727 2 0.016
regulation of response to cytokine stimulus GO:0060759 3 0.016
erk1 and erk2 cascade GO:0070371 4 0.016
regulation of dna replication GO:0006275 3 0.015
synaptic growth at neuromuscular junction GO:0051124 2 0.015
cell cycle process GO:0022402 53 0.015
single organism organelle organization GO:1902589 199 0.015
positive regulation of leukocyte mediated immunity GO:0002705 1 0.015
Human
erythrocyte homeostasis GO:0034101 55 0.015
negative regulation of signaling GO:0023057 96 0.015
leukocyte proliferation GO:0070661 1 0.015
Mouse
transmembrane transport GO:0055085 120 0.015
germ line stem cell maintenance GO:0030718 2 0.015
regulation of anatomical structure morphogenesis GO:0022603 130 0.015
secondary metabolic process GO:0019748 3 0.015
negative regulation of macromolecule metabolic process GO:0010605 76 0.015
Human
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.015
Human
negative regulation of cellular metabolic process GO:0031324 77 0.015
Human
embryo development ending in birth or egg hatching GO:0009792 271 0.015
Mouse
negative regulation of secretion by cell GO:1903531 2 0.015
defense response GO:0006952 47 0.015
inositol lipid mediated signaling GO:0048017 2 0.015
macromolecule modification GO:0043412 111 0.015
Human Mouse
production of molecular mediator of immune response GO:0002440 2 0.015
Human Mouse
regulation of dendrite development GO:0050773 3 0.015
negative regulation of cytokine production GO:0001818 1 0.015
fatty acid biosynthetic process GO:0006633 4 0.015
response to corticosteroid GO:0031960 1 0.015
regulation of transporter activity GO:0032409 2 0.015
signal transduction in absence of ligand GO:0038034 1 0.015
positive regulation of neuron death GO:1901216 1 0.015
positive regulation of innate immune response GO:0045089 8 0.014
response to glucose GO:0009749 3 0.014
localization of cell GO:0051674 244 0.014
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.014
negative regulation of protein transport GO:0051224 3 0.014
glial cell migration GO:0008347 3 0.014
innate immune response GO:0045087 13 0.014
digestive system development GO:0055123 289 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.014
ovulation cycle process GO:0022602 2 0.014
regulation of cell activation GO:0050865 1 0.014
Mouse
negative regulation of cell death GO:0060548 60 0.014
cellular response to chemical stimulus GO:0070887 157 0.014
Human Mouse Rat
regulation of cellular protein metabolic process GO:0032268 52 0.014
Human
positive regulation of cell adhesion GO:0045785 1 0.014
defense response to fungus GO:0050832 2 0.014
development of primary female sexual characteristics GO:0046545 4 0.014
developmental growth involved in morphogenesis GO:0060560 86 0.014
heart process GO:0003015 71 0.014
regulation of stem cell differentiation GO:2000736 4 0.014
response to hydrogen peroxide GO:0042542 3 0.014
axon guidance GO:0007411 86 0.014
digestive tract morphogenesis GO:0048546 231 0.014
positive regulation of lipase activity GO:0060193 1 0.014
carbohydrate homeostasis GO:0033500 1 0.014
response to topologically incorrect protein GO:0035966 2 0.014
negative regulation of kinase activity GO:0033673 4 0.014
chemosensory behavior GO:0007635 1 0.014
regulation of organ growth GO:0046620 3 0.014
organic acid catabolic process GO:0016054 3 0.014
liver development GO:0001889 96 0.014
peripheral nervous system development GO:0007422 55 0.014
negative regulation of mapk cascade GO:0043409 4 0.013
negative regulation of protein kinase activity GO:0006469 4 0.013
cellular response to organic substance GO:0071310 105 0.013
Human Mouse Rat
cellular response to unfolded protein GO:0034620 2 0.013
cellular localization GO:0051641 97 0.013
Mouse
regulation of cell shape GO:0008360 1 0.013
regulation of synaptic plasticity GO:0048167 1 0.013
adult behavior GO:0030534 2 0.013
response to lipid GO:0033993 60 0.013
Human Mouse
regulation of mitochondrion organization GO:0010821 1 0.013
golgi vesicle transport GO:0048193 3 0.013
neurological system process GO:0050877 62 0.013
negative regulation of biosynthetic process GO:0009890 55 0.013
Human
response to vitamin GO:0033273 3 0.013
positive regulation of cell activation GO:0050867 1 0.013
Mouse
monovalent inorganic cation transport GO:0015672 42 0.013
regulation of immune response GO:0050776 14 0.013
Human
positive regulation of production of molecular mediator of immune response GO:0002702 1 0.013
Human
negative regulation of immune response GO:0050777 2 0.013
regulation of localization GO:0032879 104 0.013
Mouse
organic substance transport GO:0071702 58 0.013
Mouse
spermatid development GO:0007286 2 0.013
type i interferon biosynthetic process GO:0045351 1 0.013
regulation of type i interferon production GO:0032479 2 0.013
response to abiotic stimulus GO:0009628 122 0.013
interspecies interaction between organisms GO:0044419 4 0.013
metal ion transport GO:0030001 58 0.013
apoptotic signaling pathway GO:0097190 23 0.013
regulation of response to external stimulus GO:0032101 31 0.013
Mouse
ion transmembrane transport GO:0034220 91 0.012
immune response regulating signaling pathway GO:0002764 5 0.012
Human
mitotic g2 m transition checkpoint GO:0044818 3 0.012
positive regulation of inflammatory response GO:0050729 1 0.012
head development GO:0060322 303 0.012
compound eye development GO:0048749 2 0.012
activation of mapk activity GO:0000187 3 0.012
regulation of tube size GO:0035150 2 0.012
hormone biosynthetic process GO:0042446 3 0.012
regulation of epithelial cell proliferation GO:0050678 3 0.012
multi organism cellular process GO:0044764 2 0.012
positive regulation of gene expression GO:0010628 71 0.012
negative regulation of defense response GO:0031348 2 0.012
cell proliferation GO:0008283 80 0.012
Mouse Rat
positive regulation of nucleic acid templated transcription GO:1903508 57 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.012
amide biosynthetic process GO:0043604 1 0.012
regulation of multicellular organismal development GO:2000026 223 0.012
Human
innate immune response activating signal transduction GO:0002758 5 0.012
cellular transition metal ion homeostasis GO:0046916 3 0.012
regulation of synapse assembly GO:0051963 3 0.012
regulation of stem cell proliferation GO:0072091 2 0.012
positive regulation of translation GO:0045727 1 0.012
endosomal transport GO:0016197 2 0.012
regulation of erk1 and erk2 cascade GO:0070372 4 0.012
response to wounding GO:0009611 116 0.012
mitotic cytokinesis GO:0000281 3 0.012
cation transport GO:0006812 81 0.012
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.012
g2 dna damage checkpoint GO:0031572 3 0.012
lymphocyte proliferation GO:0046651 1 0.012
Mouse
regulation of dna templated transcription in response to stress GO:0043620 0 0.012
sensory perception of pain GO:0019233 1 0.012
myeloid cell homeostasis GO:0002262 56 0.012
regeneration GO:0031099 91 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.012
glucose import GO:0046323 2 0.012
positive regulation of immune system process GO:0002684 17 0.012
Human Mouse
purine nucleoside monophosphate catabolic process GO:0009128 4 0.012
mitotic g2 dna damage checkpoint GO:0007095 3 0.011

traf6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032
nervous system disease DOID:863 0 0.018
disease of cellular proliferation DOID:14566 0 0.014
cancer DOID:162 0 0.014
organ system cancer DOID:0050686 0 0.013
disease of metabolism DOID:0014667 0 0.011