Danio rerio

47 known processes

tsc1a

tuberous sclerosis 1a

(Aliases: zgc:63657,wu:fa99f04,fa99f04)

tsc1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular component morphogenesis GO:0032989 336 0.248
larval development GO:0002164 2 0.193
digestive tract development GO:0048565 265 0.159
heart development GO:0007507 313 0.154
Mouse
nucleic acid metabolic process GO:0090304 244 0.151
cellular nitrogen compound metabolic process GO:0034641 290 0.125
Human Fly
organic cyclic compound metabolic process GO:1901360 301 0.115
Human Fly
regulation of synapse assembly GO:0051963 3 0.115
nucleocytoplasmic transport GO:0006913 4 0.114
Human
regulation of synapse organization GO:0050807 3 0.111
tube morphogenesis GO:0035239 349 0.109
Mouse
cell morphogenesis GO:0000902 289 0.107
cellular component biogenesis GO:0044085 178 0.105
Human
amine metabolic process GO:0009308 2 0.104
digestive system development GO:0055123 289 0.103
cellular ketone metabolic process GO:0042180 11 0.098
ameboidal type cell migration GO:0001667 143 0.095
protein metabolic process GO:0019538 183 0.094
Human Mouse
vasculature development GO:0001944 278 0.093
cell projection organization GO:0030030 284 0.088
sensory organ development GO:0007423 393 0.080
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.079
generation of neurons GO:0048699 385 0.079
developmental growth GO:0048589 166 0.076
Fly
central nervous system development GO:0007417 387 0.076
Mouse
growth GO:0040007 174 0.075
Fly
system process GO:0003008 185 0.074
Mouse
signal transduction GO:0007165 455 0.072
neuron differentiation GO:0030182 353 0.072
phosphorylation GO:0016310 69 0.071
Mouse Fly
protein localization to nucleus GO:0034504 3 0.071
regulation of multicellular organism growth GO:0040014 4 0.069
heterocycle metabolic process GO:0046483 290 0.068
Human Fly
cellular response to extracellular stimulus GO:0031668 2 0.067
peptidyl serine phosphorylation GO:0018105 1 0.065
mitochondrion organization GO:0007005 4 0.065
regulation of signal transduction GO:0009966 225 0.064
regulation of cellular amino acid metabolic process GO:0006521 0 0.063
peptidyl serine modification GO:0018209 2 0.061
locomotion GO:0040011 313 0.060
regulation of biosynthetic process GO:0009889 250 0.059
Human
response to stress GO:0006950 263 0.059
Fly
single organism metabolic process GO:0044710 217 0.058
Human Fly
regulation of cellular biosynthetic process GO:0031326 245 0.057
Human
protein import into nucleus GO:0006606 3 0.055
organelle organization GO:0006996 227 0.055
Human
blood vessel development GO:0001568 246 0.055
regulation of establishment of protein localization GO:0070201 4 0.055
cellular amine metabolic process GO:0044106 2 0.055
cellular biosynthetic process GO:0044249 286 0.054
Human
carboxylic acid metabolic process GO:0019752 22 0.054
regulation of primary metabolic process GO:0080090 311 0.054
Human Mouse Fly
cellular response to external stimulus GO:0071496 2 0.054
regulation of cellular amine metabolic process GO:0033238 0 0.053
lipid storage GO:0019915 1 0.053
regulation of organ growth GO:0046620 3 0.053
Fly
cellular component assembly GO:0022607 170 0.052
Human
positive regulation of cell cycle GO:0045787 3 0.051
regulation of nitrogen compound metabolic process GO:0051171 251 0.051
Human Fly
cell surface receptor signaling pathway GO:0007166 325 0.051
Fly
muscle cell differentiation GO:0042692 139 0.051
Mouse
small gtpase mediated signal transduction GO:0007264 8 0.050
stem cell proliferation GO:0072089 4 0.048
regulation of cytoplasmic transport GO:1903649 4 0.047
organelle assembly GO:0070925 110 0.046
blood vessel morphogenesis GO:0048514 216 0.046
multicellular organism growth GO:0035264 4 0.046
lateral inhibition GO:0046331 1 0.046
regulation of systemic arterial blood pressure GO:0003073 1 0.046
blood circulation GO:0008015 87 0.045
synaptic growth at neuromuscular junction GO:0051124 2 0.045
regulation of intracellular protein transport GO:0033157 3 0.045
single organism nuclear import GO:1902593 3 0.045
meiotic nuclear division GO:0007126 4 0.044
regulation of metal ion transport GO:0010959 4 0.043
positive regulation of transport GO:0051050 2 0.043
regulation of protein transport GO:0051223 3 0.043
maintenance of location GO:0051235 4 0.042
regulation of macromolecule metabolic process GO:0060255 317 0.042
Human Mouse
extrinsic apoptotic signaling pathway GO:0097191 3 0.042
regulation of cellular metabolic process GO:0031323 320 0.042
Human Mouse Fly
cellular macromolecule metabolic process GO:0044260 391 0.042
Human Mouse
protein targeting to nucleus GO:0044744 3 0.041
modification dependent protein catabolic process GO:0019941 3 0.041
regulation of metabolic process GO:0019222 359 0.041
Human Mouse Fly
autophagy GO:0006914 4 0.041
Fly
biosynthetic process GO:0009058 294 0.041
Human
organic acid metabolic process GO:0006082 31 0.040
lipid catabolic process GO:0016042 4 0.040
regulation of cellular ketone metabolic process GO:0010565 7 0.040
eye morphogenesis GO:0048592 144 0.039
aging GO:0007568 2 0.039
Fly
nitrogen compound metabolic process GO:0006807 319 0.039
Human Fly
neuron projection development GO:0031175 180 0.039
negative regulation of cellular process GO:0048523 283 0.038
Human Mouse Fly
digestive tract morphogenesis GO:0048546 231 0.038
regulation of transcription dna templated GO:0006355 213 0.037
aromatic compound biosynthetic process GO:0019438 217 0.037
regulation of carbohydrate metabolic process GO:0006109 4 0.037
nitric oxide biosynthetic process GO:0006809 2 0.037
gastrulation GO:0007369 208 0.036
locomotor rhythm GO:0045475 3 0.036
zymogen activation GO:0031638 3 0.036
regulation of autophagy GO:0010506 3 0.036
Fly
regulation of molecular function GO:0065009 70 0.036
Human Mouse Fly
regulation of protein ubiquitination GO:0031396 3 0.035
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.035
negative regulation of cell communication GO:0010648 96 0.035
Human Fly
cell matrix adhesion GO:0007160 4 0.035
Human
cellular response to nutrient levels GO:0031669 2 0.035
negative regulation of metabolic process GO:0009892 86 0.034
Human
adherens junction organization GO:0034332 4 0.034
Human
positive regulation of biological process GO:0048518 253 0.034
Human Fly
regulation of skeletal muscle fiber development GO:0048742 2 0.034
cognition GO:0050890 1 0.034
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.034
Human Fly
cellular carbohydrate metabolic process GO:0044262 4 0.034
negative regulation of catabolic process GO:0009895 3 0.034
establishment of protein localization to organelle GO:0072594 4 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.033
organic cyclic compound biosynthetic process GO:1901362 223 0.033
cell migration GO:0016477 237 0.033
circulatory system process GO:0003013 87 0.033
long chain fatty acid transport GO:0015909 1 0.032
regulation of circadian rhythm GO:0042752 4 0.032
rna biosynthetic process GO:0032774 181 0.032
cellular response to starvation GO:0009267 1 0.032
cell aging GO:0007569 2 0.032
guanosine containing compound metabolic process GO:1901068 4 0.031
Human Fly
morphogenesis of an epithelium GO:0002009 333 0.031
Mouse
regulation of protein targeting GO:1903533 2 0.031
cellular component movement GO:0006928 335 0.031
regulation of rna metabolic process GO:0051252 224 0.030
nuclear import GO:0051170 3 0.030
guanosine containing compound catabolic process GO:1901069 2 0.030
Human Fly
small molecule metabolic process GO:0044281 77 0.030
Human Fly
regulation of cell communication GO:0010646 232 0.030
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.030
cellular amino acid metabolic process GO:0006520 7 0.030
regulation of response to stimulus GO:0048583 269 0.030
nucleobase containing compound metabolic process GO:0006139 274 0.030
Human Fly
cellular protein modification process GO:0006464 100 0.030
Mouse
neuron development GO:0048666 262 0.029
negative regulation of cellular metabolic process GO:0031324 77 0.029
Human
protein complex subunit organization GO:0071822 46 0.029
Human
gene expression GO:0010467 252 0.029
Human
regulation of dna replication GO:0006275 3 0.029
regulation of biological quality GO:0065008 263 0.029
Human Mouse Fly
response to corticosteroid GO:0031960 1 0.029
cellular response to chemical stimulus GO:0070887 157 0.029
Fly
negative regulation of biological process GO:0048519 304 0.029
Human Mouse Fly
response to external stimulus GO:0009605 264 0.028
Fly
regulation of cellular component organization GO:0051128 86 0.028
Human Fly
neurotransmitter secretion GO:0007269 2 0.028
cell motility GO:0048870 244 0.028
organic substance biosynthetic process GO:1901576 289 0.028
Human
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.028
post embryonic organ development GO:0048569 4 0.028
regulation of developmental process GO:0050793 247 0.028
Fly
cell projection morphogenesis GO:0048858 244 0.028
macromolecule modification GO:0043412 111 0.027
Mouse
gtp metabolic process GO:0046039 4 0.027
Human Fly
regulation of protein metabolic process GO:0051246 56 0.027
Human Mouse
positive regulation of cellular component biogenesis GO:0044089 3 0.027
Human
regulation of reactive oxygen species metabolic process GO:2000377 2 0.027
Fly
neuron neuron synaptic transmission GO:0007270 1 0.026
ras protein signal transduction GO:0007265 7 0.026
cell part morphogenesis GO:0032990 246 0.026
cellular lipid catabolic process GO:0044242 3 0.026
nitric oxide metabolic process GO:0046209 2 0.026
hormone transport GO:0009914 2 0.026
regulation of binding GO:0051098 3 0.025
neuroblast proliferation GO:0007405 2 0.025
cellular protein catabolic process GO:0044257 4 0.025
embryonic organ development GO:0048568 381 0.025
adherens junction maintenance GO:0034334 2 0.025
germ line stem cell division GO:0042078 1 0.025
cellular lipid metabolic process GO:0044255 36 0.025
bmp signaling pathway GO:0030509 52 0.025
cellular component disassembly GO:0022411 1 0.025
negative regulation of epithelial cell proliferation GO:0050680 1 0.025
regulation of cysteine type endopeptidase activity GO:2000116 21 0.025
negative regulation of protein phosphorylation GO:0001933 4 0.025
somatic muscle development GO:0007525 4 0.025
glucose import GO:0046323 2 0.025
Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.024
immune system development GO:0002520 191 0.024
macroautophagy GO:0016236 1 0.024
neurotransmitter transport GO:0006836 2 0.024
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.024
gtp catabolic process GO:0006184 2 0.024
Human Fly
regulation of rna biosynthetic process GO:2001141 213 0.024
regulation of purine nucleotide catabolic process GO:0033121 2 0.024
Human Fly
striated muscle cell development GO:0055002 108 0.024
phagocytosis GO:0006909 3 0.024
negative regulation of cellular catabolic process GO:0031330 3 0.024
circadian sleep wake cycle process GO:0022410 2 0.024
peptidyl threonine modification GO:0018210 1 0.024
regulation of gtp catabolic process GO:0033124 2 0.024
Human Fly
positive regulation of cellular amine metabolic process GO:0033240 0 0.024
heterocycle biosynthetic process GO:0018130 215 0.023
medulla oblongata development GO:0021550 4 0.023
protein import GO:0017038 3 0.023
regulation of neurotransmitter transport GO:0051588 1 0.023
reactive oxygen species biosynthetic process GO:1903409 1 0.023
regulation of protein localization to nucleus GO:1900180 2 0.023
regulation of dna templated transcription in response to stress GO:0043620 0 0.023
regulation of nucleocytoplasmic transport GO:0046822 2 0.023
regulation of synaptic plasticity GO:0048167 1 0.023
localization of cell GO:0051674 244 0.023
adult behavior GO:0030534 2 0.023
regulation of neuron differentiation GO:0045664 56 0.023
cell substrate adhesion GO:0031589 4 0.023
Human
startle response GO:0001964 4 0.023
embryonic heart tube development GO:0035050 133 0.023
hemopoiesis GO:0030097 183 0.023
membrane invagination GO:0010324 1 0.022
negative regulation of protein transport GO:0051224 3 0.022
muscle structure development GO:0061061 196 0.022
Mouse
regulation of protein complex assembly GO:0043254 3 0.022
positive regulation of cellular process GO:0048522 201 0.022
Human Fly
response to nutrient GO:0007584 3 0.022
Fly
protein localization to plasma membrane GO:0072659 1 0.022
negative regulation of biosynthetic process GO:0009890 55 0.022
Human
organonitrogen compound metabolic process GO:1901564 74 0.022
Human Fly
nucleic acid templated transcription GO:0097659 181 0.022
regulation of protein catabolic process GO:0042176 1 0.022
glucose homeostasis GO:0042593 1 0.022
negative regulation of protein kinase activity GO:0006469 4 0.022
regulation of bmp signaling pathway GO:0030510 39 0.022
negative regulation of synapse assembly GO:0051964 2 0.022
transcription dna templated GO:0006351 181 0.022
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.022
stem cell division GO:0017145 1 0.022
regulation of jak stat cascade GO:0046425 3 0.021
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.021
eye development GO:0001654 277 0.021
regulation of programmed cell death GO:0043067 101 0.021
circadian sleep wake cycle GO:0042745 2 0.021
mitotic dna integrity checkpoint GO:0044774 4 0.021
peptidyl threonine phosphorylation GO:0018107 1 0.021
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.021
hematopoietic or lymphoid organ development GO:0048534 191 0.021
carbohydrate biosynthetic process GO:0016051 1 0.021
positive regulation of cell communication GO:0010647 56 0.021
positive regulation of carbohydrate metabolic process GO:0045913 1 0.021
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.021
regulation of gene expression GO:0010468 265 0.021
Human
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.021
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.020
nuclear transport GO:0051169 4 0.020
Human
regulation of sodium ion transport GO:0002028 2 0.020
single organism organelle organization GO:1902589 199 0.020
Human
stem cell maintenance GO:0019827 4 0.020
cell morphogenesis involved in differentiation GO:0000904 195 0.020
oxoacid metabolic process GO:0043436 31 0.020
modification dependent macromolecule catabolic process GO:0043632 3 0.020
negative regulation of mapk cascade GO:0043409 4 0.020
intracellular signal transduction GO:0035556 85 0.020
regulation of stem cell differentiation GO:2000736 4 0.020
negative regulation of autophagy GO:0010507 1 0.020
proteolysis GO:0006508 38 0.020
regulation of macromolecule biosynthetic process GO:0010556 225 0.020
Human
fin morphogenesis GO:0033334 53 0.020
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.020
Human
regulation of erk1 and erk2 cascade GO:0070372 4 0.019
rna metabolic process GO:0016070 219 0.019
negative regulation of protein complex assembly GO:0031333 1 0.019
cellular macromolecule biosynthetic process GO:0034645 224 0.019
Human
axonogenesis GO:0007409 152 0.019
positive regulation of multicellular organismal process GO:0051240 52 0.019
lipid metabolic process GO:0006629 52 0.019
Fly
negative regulation of kinase activity GO:0033673 4 0.019
sensory organ morphogenesis GO:0090596 200 0.019
positive regulation of response to stimulus GO:0048584 80 0.019
macromolecular complex disassembly GO:0032984 1 0.019
regulation of protein binding GO:0043393 3 0.019
positive regulation of catabolic process GO:0009896 4 0.019
Human Fly
antimicrobial humoral response GO:0019730 2 0.019
neuron projection morphogenesis GO:0048812 161 0.019
angiogenesis GO:0001525 158 0.019
protein modification process GO:0036211 100 0.018
Mouse
regulation of cell shape GO:0008360 1 0.018
regulation of nucleic acid templated transcription GO:1903506 213 0.018
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.018
camera type eye morphogenesis GO:0048593 108 0.018
heart contraction GO:0060047 71 0.018
regionalization GO:0003002 274 0.018
phagocytosis engulfment GO:0006911 1 0.018
regulation of epithelial cell proliferation GO:0050678 3 0.018
cellular biogenic amine metabolic process GO:0006576 2 0.018
regulation of intracellular signal transduction GO:1902531 57 0.018
hypothalamus cell differentiation GO:0021979 4 0.018
cell proliferation GO:0008283 80 0.018
Human Mouse Fly
multi organism process GO:0051704 134 0.018
Fly
reactive nitrogen species metabolic process GO:2001057 0 0.018
positive regulation of cellular metabolic process GO:0031325 94 0.018
Human Fly
lipid oxidation GO:0034440 1 0.018
protein acylation GO:0043543 3 0.017
heart process GO:0003015 71 0.017
developmental pigmentation GO:0048066 48 0.017
regulation of apoptotic process GO:0042981 98 0.017
convergent extension GO:0060026 118 0.017
actin cytoskeleton organization GO:0030036 63 0.017
Human
response to hexose GO:0009746 3 0.017
nucleobase containing compound biosynthetic process GO:0034654 205 0.017
cytokinesis GO:0000910 3 0.017
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.017
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.017
meiotic cell cycle process GO:1903046 3 0.017
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.017
regulation of heart growth GO:0060420 2 0.017
positive regulation of nucleoside metabolic process GO:0045979 1 0.017
Human Fly
enzyme linked receptor protein signaling pathway GO:0007167 106 0.017
Fly
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.017
regulation of response to nutrient levels GO:0032107 1 0.017
regulation of vasculature development GO:1901342 33 0.017
positive regulation of gliogenesis GO:0014015 2 0.017
locomotory behavior GO:0007626 34 0.017
cellular localization GO:0051641 97 0.017
Human
negative regulation of map kinase activity GO:0043407 2 0.017
centrosome organization GO:0051297 1 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.017
embryonic organ morphogenesis GO:0048562 274 0.017
female gonad development GO:0008585 4 0.016
pharyngeal muscle development GO:0043282 4 0.016
regulation of nucleotide catabolic process GO:0030811 2 0.016
Human Fly
actomyosin structure organization GO:0031032 53 0.016
Human
transmission of nerve impulse GO:0019226 19 0.016
Mouse
regulation of hormone secretion GO:0046883 2 0.016
cellular component assembly involved in morphogenesis GO:0010927 107 0.016
development of primary female sexual characteristics GO:0046545 4 0.016
carbohydrate homeostasis GO:0033500 1 0.016
hormone secretion GO:0046879 2 0.016
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.016
regulation of anatomical structure morphogenesis GO:0022603 130 0.016
regulation of multicellular organismal process GO:0051239 277 0.016
Fly
convergent extension involved in gastrulation GO:0060027 71 0.016
regulation of dna templated transcription elongation GO:0032784 3 0.016
regulation of catalytic activity GO:0050790 55 0.016
Human Mouse Fly
regulation of blood circulation GO:1903522 32 0.016
tissue remodeling GO:0048771 4 0.016
regulation of multicellular organismal development GO:2000026 223 0.016
programmed cell death GO:0012501 119 0.016
camera type eye development GO:0043010 222 0.016
energy reserve metabolic process GO:0006112 2 0.016
appendage development GO:0048736 80 0.016
regulation of response to extracellular stimulus GO:0032104 1 0.015
response to carbohydrate GO:0009743 3 0.015
positive regulation of muscle organ development GO:0048636 1 0.015
single organism carbohydrate metabolic process GO:0044723 12 0.015
cell death GO:0008219 121 0.015
erk1 and erk2 cascade GO:0070371 4 0.015
establishment of synaptic vesicle localization GO:0097480 1 0.015
actin polymerization or depolymerization GO:0008154 2 0.015
regulation of tube size GO:0035150 2 0.015
mitotic dna damage checkpoint GO:0044773 4 0.015
regeneration GO:0031099 91 0.015
cilium morphogenesis GO:0060271 85 0.015
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.015
protein phosphorylation GO:0006468 47 0.015
Mouse
regulation of blood vessel size GO:0050880 2 0.015
multicellular organismal signaling GO:0035637 22 0.015
Mouse
spindle assembly GO:0051225 2 0.015
regulation of nervous system development GO:0051960 90 0.015
membrane fusion GO:0061025 2 0.015
response to drug GO:0042493 3 0.015
negative regulation of gene expression GO:0010629 65 0.015
Human
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 7 0.015
regulation of cell substrate adhesion GO:0010810 1 0.015
Human
response to osmotic stress GO:0006970 11 0.014
axon development GO:0061564 166 0.014
cellular protein metabolic process GO:0044267 129 0.014
Human Mouse
proteasomal protein catabolic process GO:0010498 2 0.014
circadian sleep wake cycle sleep GO:0050802 1 0.014
apoptotic process GO:0006915 116 0.014
cellular component maintenance GO:0043954 3 0.014
branching morphogenesis of a nerve GO:0048755 4 0.014
negative regulation of rna metabolic process GO:0051253 48 0.014
death GO:0016265 121 0.014
Fly
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.014
dopamine metabolic process GO:0042417 2 0.014
positive regulation of signaling GO:0023056 56 0.014
positive regulation of cellular catabolic process GO:0031331 3 0.014
Human Fly
regulation of oocyte development GO:0060281 3 0.014
protein complex disassembly GO:0043241 1 0.014
positive regulation of striated muscle tissue development GO:0045844 1 0.014
sensory perception of pain GO:0019233 1 0.014
multicellular organismal metabolic process GO:0044236 2 0.014
regulation of lipid catabolic process GO:0050994 2 0.014
heart morphogenesis GO:0003007 156 0.014
water homeostasis GO:0030104 4 0.014
regulation of blood pressure GO:0008217 1 0.014
cellular response to hypoxia GO:0071456 1 0.013
Fly
protein polymerization GO:0051258 4 0.013
establishment of localization GO:0051234 244 0.013
Human Mouse
response to uv GO:0009411 3 0.013
cell cell signaling GO:0007267 52 0.013
immune system process GO:0002376 241 0.013
regulation of cell development GO:0060284 100 0.013
positive regulation of cell division GO:0051781 2 0.013
regulation of photoreceptor cell differentiation GO:0046532 2 0.013
transport GO:0006810 220 0.013
Human Mouse
negative regulation of cytoplasmic transport GO:1903650 2 0.013
connective tissue development GO:0061448 99 0.013
iron ion homeostasis GO:0055072 4 0.013
regulation of skeletal muscle tissue development GO:0048641 4 0.013
epithelial cell migration GO:0010631 25 0.013
single organism transport GO:0044765 206 0.013
Human Mouse
regulation of circadian sleep wake cycle GO:0042749 1 0.013
negative regulation of macromolecule metabolic process GO:0010605 76 0.013
Human
muscle cell development GO:0055001 115 0.013
catecholamine metabolic process GO:0006584 2 0.013
phosphate containing compound metabolic process GO:0006796 108 0.013
Human Mouse Fly
nephron tubule morphogenesis GO:0072078 1 0.013
negative regulation of intracellular protein transport GO:0090317 3 0.013
positive regulation of dna templated transcription elongation GO:0032786 1 0.013
regulation of dendrite development GO:0050773 3 0.013
meiotic chromosome segregation GO:0045132 3 0.013
protein complex assembly GO:0006461 30 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.013
Human Fly
regulation of anatomical structure size GO:0090066 33 0.013
Mouse Fly
smooth muscle tissue development GO:0048745 1 0.013
regulation of myotube differentiation GO:0010830 2 0.013
response to glucocorticoid GO:0051384 1 0.013
cellular response to stress GO:0033554 62 0.013
Fly
epithelial cell differentiation GO:0030855 116 0.013
Fly
respiratory electron transport chain GO:0022904 2 0.013
microtubule organizing center organization GO:0031023 1 0.013
porphyrin containing compound metabolic process GO:0006778 10 0.013
production of molecular mediator of immune response GO:0002440 2 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.013
positive regulation of gtp catabolic process GO:0033126 1 0.013
Human Fly
cellular modified amino acid metabolic process GO:0006575 3 0.013
regulation of developmental growth GO:0048638 38 0.013
Fly
peripheral nervous system neuron differentiation GO:0048934 28 0.013
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.012
regulation of ion transmembrane transporter activity GO:0032412 2 0.012
cellular aromatic compound metabolic process GO:0006725 295 0.012
Human Fly
response to abiotic stimulus GO:0009628 122 0.012
Fly
negative regulation of chemotaxis GO:0050922 4 0.012
negative regulation of apoptotic process GO:0043066 55 0.012
mesenchymal cell development GO:0014031 78 0.012
embryonic skeletal joint development GO:0072498 3 0.012
dorsal ventral pattern formation GO:0009953 125 0.012
protein acetylation GO:0006473 2 0.012
regulation of meiotic cell cycle GO:0051445 1 0.012
maternal determination of anterior posterior axis embryo GO:0008358 4 0.012
post embryonic morphogenesis GO:0009886 4 0.012
Fly
regulation of cell differentiation GO:0045595 142 0.012
Fly
negative regulation of intracellular signal transduction GO:1902532 22 0.012
Human Fly
regulation of reproductive process GO:2000241 4 0.012
nephron morphogenesis GO:0072028 2 0.012
response to monosaccharide GO:0034284 3 0.012
anterior posterior pattern specification GO:0009952 152 0.012
cofactor metabolic process GO:0051186 15 0.012
response to ketone GO:1901654 1 0.012
regulation of transmembrane transporter activity GO:0022898 2 0.012
chordate embryonic development GO:0043009 271 0.012
Mouse
regulation of glucose import GO:0046324 1 0.012
multicellular organismal homeostasis GO:0048871 29 0.012
p38mapk cascade GO:0038066 1 0.012
regulation of cell death GO:0010941 103 0.012
regulation of cell matrix adhesion GO:0001952 1 0.012
Human
ubiquitin dependent protein catabolic process GO:0006511 3 0.012
regulation of lipid transport GO:0032368 4 0.012
ear development GO:0043583 127 0.012
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.012
response to chemical GO:0042221 320 0.012
Human Fly
regulation of fatty acid metabolic process GO:0019217 1 0.012
pigment cell differentiation GO:0050931 38 0.012
vasculogenesis GO:0001570 41 0.012
positive regulation of lipid metabolic process GO:0045834 1 0.012
cell growth GO:0016049 57 0.012
Fly
regulation of cellular protein catabolic process GO:1903362 1 0.012
rna localization GO:0006403 4 0.011
Human
regulation of glucose transport GO:0010827 1 0.011
negative regulation of dna replication GO:0008156 2 0.011
fatty acid oxidation GO:0019395 1 0.011
modification of morphology or physiology of other organism GO:0035821 4 0.011
cellular response to xenobiotic stimulus GO:0071466 35 0.011
response to wounding GO:0009611 116 0.011
negative regulation of dna metabolic process GO:0051053 4 0.011
skeletal muscle tissue development GO:0007519 67 0.011
positive regulation of macromolecule metabolic process GO:0010604 93 0.011
regulation of protein import into nucleus GO:0042306 2 0.011

tsc1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
disease of metabolism DOID:0014667 0 0.019
inherited metabolic disorder DOID:655 0 0.018
nervous system disease DOID:863 0 0.014
cancer DOID:162 0 0.013
organ system cancer DOID:0050686 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
immune system disease DOID:2914 0 0.012
musculoskeletal system disease DOID:17 0 0.011