Danio rerio

46 known processes

tsc2

tuberous sclerosis 2

(Aliases: wu:fc16b02,tuberin,fc16b02)

tsc2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell motility GO:0048870 244 0.167
chordate embryonic development GO:0043009 271 0.158
cellular component movement GO:0006928 335 0.133
single organism transport GO:0044765 206 0.127
organelle organization GO:0006996 227 0.126
sensory organ development GO:0007423 393 0.126
meiotic nuclear division GO:0007126 4 0.121
cellular protein catabolic process GO:0044257 4 0.111
head development GO:0060322 303 0.098
multicellular organism growth GO:0035264 4 0.094
establishment of localization GO:0051234 244 0.092
single organism localization GO:1902578 225 0.088
protein localization to nucleus GO:0034504 3 0.084
protein targeting to nucleus GO:0044744 3 0.084
larval development GO:0002164 2 0.082
aging GO:0007568 2 0.081
brain development GO:0007420 293 0.077
organelle assembly GO:0070925 110 0.075
cell projection morphogenesis GO:0048858 244 0.074
immune system development GO:0002520 191 0.074
morphogenesis of an epithelium GO:0002009 333 0.073
single organism nuclear import GO:1902593 3 0.071
central nervous system development GO:0007417 387 0.070
axon guidance GO:0007411 86 0.070
carboxylic acid catabolic process GO:0046395 3 0.069
digestive tract development GO:0048565 265 0.069
regulation of stem cell proliferation GO:0072091 2 0.068
blood vessel morphogenesis GO:0048514 216 0.066
regulation of cell matrix adhesion GO:0001952 1 0.066
lipid catabolic process GO:0016042 4 0.066
nitrogen compound metabolic process GO:0006807 319 0.065
cell substrate adhesion GO:0031589 4 0.064
protein import GO:0017038 3 0.064
embryonic cranial skeleton morphogenesis GO:0048701 90 0.063
regulation of multicellular organism growth GO:0040014 4 0.061
regulation of metabolic process GO:0019222 359 0.061
vasculature development GO:0001944 278 0.061
spindle assembly GO:0051225 2 0.059
protein import into nucleus GO:0006606 3 0.057
cell part morphogenesis GO:0032990 246 0.057
myeloid cell differentiation GO:0030099 86 0.056
establishment of protein localization to organelle GO:0072594 4 0.055
determination of left right symmetry GO:0007368 179 0.055
mitochondrion morphogenesis GO:0070584 2 0.055
meiotic cell cycle process GO:1903046 3 0.055
cilium morphogenesis GO:0060271 85 0.054
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.054
cellular ketone metabolic process GO:0042180 11 0.053
eye development GO:0001654 277 0.053
regulation of endothelial cell proliferation GO:0001936 1 0.052
generation of neurons GO:0048699 385 0.051
single organism metabolic process GO:0044710 217 0.051
locomotor rhythm GO:0045475 3 0.051
growth GO:0040007 174 0.051
oxoacid metabolic process GO:0043436 31 0.050
cell matrix adhesion GO:0007160 4 0.050
cellular macromolecule metabolic process GO:0044260 391 0.050
glial cell proliferation GO:0014009 4 0.050
determination of bilateral symmetry GO:0009855 204 0.049
regulation of erk1 and erk2 cascade GO:0070372 4 0.048
cellular biosynthetic process GO:0044249 286 0.048
establishment of melanosome localization GO:0032401 19 0.048
embryonic organ morphogenesis GO:0048562 274 0.047
negative regulation of ras protein signal transduction GO:0046580 1 0.046
guanosine containing compound metabolic process GO:1901068 4 0.046
nuclear import GO:0051170 3 0.046
meiotic chromosome segregation GO:0045132 3 0.046
organic acid catabolic process GO:0016054 3 0.044
cellular component biogenesis GO:0044085 178 0.044
specification of symmetry GO:0009799 204 0.044
single organism organelle organization GO:1902589 199 0.044
sensory organ morphogenesis GO:0090596 200 0.044
negative regulation of protein transport GO:0051224 3 0.044
modification dependent protein catabolic process GO:0019941 3 0.044
positive regulation of camp biosynthetic process GO:0030819 2 0.044
regulation of nucleoside metabolic process GO:0009118 2 0.043
regulation of neural precursor cell proliferation GO:2000177 3 0.043
positive regulation of epithelial cell proliferation GO:0050679 1 0.043
stem cell proliferation GO:0072089 4 0.042
microtubule organizing center organization GO:0031023 1 0.041
guanosine containing compound catabolic process GO:1901069 2 0.041
cytoskeleton organization GO:0007010 96 0.041
negative regulation of gliogenesis GO:0014014 1 0.040
locomotion GO:0040011 313 0.040
fatty acid beta oxidation GO:0006635 1 0.040
negative regulation of kinase activity GO:0033673 4 0.040
localization of cell GO:0051674 244 0.040
nucleobase containing compound biosynthetic process GO:0034654 205 0.040
regulation of glial cell differentiation GO:0045685 4 0.040
neural tube development GO:0021915 62 0.039
regulation of autophagy GO:0010506 3 0.039
regulation of macromolecule metabolic process GO:0060255 317 0.039
regulation of cellular ketone metabolic process GO:0010565 7 0.039
ameboidal type cell migration GO:0001667 143 0.039
single organism cellular localization GO:1902580 46 0.038
modification dependent macromolecule catabolic process GO:0043632 3 0.038
positive regulation of catabolic process GO:0009896 4 0.038
positive regulation of cellular catabolic process GO:0031331 3 0.038
brain morphogenesis GO:0048854 18 0.038
maintenance of location GO:0051235 4 0.037
eye morphogenesis GO:0048592 144 0.037
positive regulation of endothelial cell proliferation GO:0001938 1 0.037
fatty acid catabolic process GO:0009062 1 0.037
liver development GO:0001889 96 0.037
blood vessel development GO:0001568 246 0.037
skeletal system morphogenesis GO:0048705 102 0.037
lipid storage GO:0019915 1 0.037
gtp metabolic process GO:0046039 4 0.037
transmission of nerve impulse GO:0019226 19 0.036
regulation of cellular metabolic process GO:0031323 320 0.036
negative regulation of cytoplasmic transport GO:1903650 2 0.036
microtubule based process GO:0007017 60 0.036
response to chemical GO:0042221 320 0.036
regulation of nucleocytoplasmic transport GO:0046822 2 0.035
negative regulation of protein kinase activity GO:0006469 4 0.035
endosomal transport GO:0016197 2 0.035
centrosome organization GO:0051297 1 0.035
cellular nitrogen compound metabolic process GO:0034641 290 0.034
synaptic growth at neuromuscular junction GO:0051124 2 0.034
skeletal system development GO:0001501 181 0.034
melanosome transport GO:0032402 19 0.034
transport GO:0006810 220 0.034
regulation of protein import into nucleus GO:0042306 2 0.034
regeneration GO:0031099 91 0.034
startle response GO:0001964 4 0.033
cellular component assembly GO:0022607 170 0.033
apoptotic process GO:0006915 116 0.033
regulation of oligodendrocyte differentiation GO:0048713 1 0.033
lipid oxidation GO:0034440 1 0.032
cellular component morphogenesis GO:0032989 336 0.031
embryonic skeletal system morphogenesis GO:0048704 93 0.031
cellular protein modification process GO:0006464 100 0.031
cellular component disassembly GO:0022411 1 0.031
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.031
small molecule metabolic process GO:0044281 77 0.031
organic acid metabolic process GO:0006082 31 0.031
negative regulation of protein phosphorylation GO:0001933 4 0.031
cellular lipid catabolic process GO:0044242 3 0.031
nucleocytoplasmic transport GO:0006913 4 0.031
regulation of multicellular organismal process GO:0051239 277 0.031
erk1 and erk2 cascade GO:0070371 4 0.031
regulation of gtp catabolic process GO:0033124 2 0.030
negative regulation of protein localization to nucleus GO:1900181 2 0.030
axon development GO:0061564 166 0.030
autophagy GO:0006914 4 0.029
developmental growth GO:0048589 166 0.029
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.029
neural crest cell development GO:0014032 62 0.029
response to drug GO:0042493 3 0.029
amine metabolic process GO:0009308 2 0.029
protein metabolic process GO:0019538 183 0.029
cellular response to hypoxia GO:0071456 1 0.028
vesicle localization GO:0051648 27 0.028
nucleobase containing compound metabolic process GO:0006139 274 0.028
regulation of nucleotide catabolic process GO:0030811 2 0.027
cellular response to extracellular stimulus GO:0031668 2 0.027
regulation of multicellular organismal development GO:2000026 223 0.027
response to external stimulus GO:0009605 264 0.027
microtubule based movement GO:0007018 33 0.027
digestive tract morphogenesis GO:0048546 231 0.027
cellular amine metabolic process GO:0044106 2 0.027
fatty acid oxidation GO:0019395 1 0.027
pigmentation GO:0043473 85 0.027
nuclear transport GO:0051169 4 0.027
collagen fibril organization GO:0030199 1 0.026
heart looping GO:0001947 94 0.026
spindle assembly involved in mitosis GO:0090307 1 0.026
regulation of intracellular protein transport GO:0033157 3 0.026
protein modification process GO:0036211 100 0.026
heterocycle metabolic process GO:0046483 290 0.026
cellular response to external stimulus GO:0071496 2 0.026
maintenance of gastrointestinal epithelium GO:0030277 7 0.026
cilium movement GO:0003341 26 0.026
embryonic organ development GO:0048568 381 0.026
macromolecule modification GO:0043412 111 0.025
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.025
proteasomal protein catabolic process GO:0010498 2 0.025
positive regulation of camp metabolic process GO:0030816 2 0.025
regulation of cellular amine metabolic process GO:0033238 0 0.025
carboxylic acid metabolic process GO:0019752 22 0.025
neural crest cell migration GO:0001755 42 0.024
organic substance catabolic process GO:1901575 28 0.024
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.024
cellular response to nutrient levels GO:0031669 2 0.024
small molecule catabolic process GO:0044282 3 0.024
renal filtration GO:0097205 10 0.024
hemopoiesis GO:0030097 183 0.024
cellular response to oxygen levels GO:0071453 1 0.024
cellular response to starvation GO:0009267 1 0.024
cell morphogenesis involved in differentiation GO:0000904 195 0.024
neuroblast proliferation GO:0007405 2 0.024
positive regulation of apoptotic signaling pathway GO:2001235 1 0.023
regulation of neurotransmitter secretion GO:0046928 1 0.023
regulation of protein binding GO:0043393 3 0.023
embryonic heart tube morphogenesis GO:0003143 108 0.023
mitochondrion organization GO:0007005 4 0.023
negative regulation of epithelial cell proliferation GO:0050680 1 0.023
regulation of binding GO:0051098 3 0.023
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
phosphate containing compound metabolic process GO:0006796 108 0.022
astrocyte differentiation GO:0048708 1 0.022
positive regulation of neuron apoptotic process GO:0043525 1 0.022
angiogenesis GO:0001525 158 0.022
muscle structure development GO:0061061 196 0.022
death GO:0016265 121 0.022
gtp catabolic process GO:0006184 2 0.022
positive regulation of stem cell proliferation GO:2000648 1 0.022
cellular aromatic compound metabolic process GO:0006725 295 0.022
digestive system development GO:0055123 289 0.022
regulation of protein targeting GO:1903533 2 0.022
cell projection organization GO:0030030 284 0.022
muscle cell development GO:0055001 115 0.021
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.021
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.021
gene expression GO:0010467 252 0.021
ubiquitin dependent protein catabolic process GO:0006511 3 0.021
extrinsic apoptotic signaling pathway GO:0097191 3 0.021
nucleoside monophosphate catabolic process GO:0009125 4 0.021
cell aging GO:0007569 2 0.021
positive regulation of gtp catabolic process GO:0033126 1 0.021
pigment granule localization GO:0051875 25 0.021
mitotic dna damage checkpoint GO:0044773 4 0.020
regulation of circadian rhythm GO:0042752 4 0.020
regulation of cellular protein catabolic process GO:1903362 1 0.020
cell morphogenesis GO:0000902 289 0.020
regulation of nitrogen compound metabolic process GO:0051171 251 0.020
protein localization GO:0008104 40 0.020
heart development GO:0007507 313 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.020
maturation of ssu rrna GO:0030490 1 0.020
embryonic heart tube development GO:0035050 133 0.020
neuron projection development GO:0031175 180 0.020
autonomic nervous system development GO:0048483 19 0.020
embryonic skeletal system development GO:0048706 97 0.020
immune system process GO:0002376 241 0.019
cell death GO:0008219 121 0.019
negative regulation of intracellular protein transport GO:0090317 3 0.019
lymphocyte proliferation GO:0046651 1 0.019
lipid metabolic process GO:0006629 52 0.019
cell cycle g1 s phase transition GO:0044843 1 0.019
embryonic viscerocranium morphogenesis GO:0048703 52 0.019
organic cyclic compound metabolic process GO:1901360 301 0.019
cellular lipid metabolic process GO:0044255 36 0.019
cell surface receptor signaling pathway GO:0007166 325 0.019
regulation of rac protein signal transduction GO:0035020 1 0.019
cognition GO:0050890 1 0.019
cellular protein metabolic process GO:0044267 129 0.019
convergent extension GO:0060026 118 0.019
negative regulation of intracellular transport GO:0032387 3 0.019
establishment of vesicle localization GO:0051650 24 0.019
somite development GO:0061053 96 0.019
mitotic dna integrity checkpoint GO:0044774 4 0.019
cellular pigmentation GO:0033059 30 0.019
regulation of production of molecular mediator of immune response GO:0002700 1 0.019
positive regulation of gtpase activity GO:0043547 1 0.018
regulation of lipid catabolic process GO:0050994 2 0.018
monocarboxylic acid catabolic process GO:0072329 3 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
regulation of epithelial cell proliferation GO:0050678 3 0.018
nucleic acid templated transcription GO:0097659 181 0.018
regulation of microtubule cytoskeleton organization GO:0070507 3 0.018
compound eye development GO:0048749 2 0.018
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.018
osteoclast differentiation GO:0030316 1 0.018
ribosomal small subunit biogenesis GO:0042274 2 0.018
neuromast development GO:0048884 46 0.018
cell migration GO:0016477 237 0.018
atp catabolic process GO:0006200 4 0.018
convergent extension involved in gastrulation GO:0060027 71 0.018
dna metabolic process GO:0006259 27 0.018
meiosis i GO:0007127 1 0.018
organic substance biosynthetic process GO:1901576 289 0.018
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.018
determination of heart left right asymmetry GO:0061371 117 0.018
stem cell differentiation GO:0048863 117 0.018
regulation of ras gtpase activity GO:0032318 2 0.017
regulation of protein transport GO:0051223 3 0.017
homeostasis of number of cells GO:0048872 62 0.017
neurotransmitter secretion GO:0007269 2 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
regulation of synapse organization GO:0050807 3 0.017
positive regulation of nucleoside metabolic process GO:0045979 1 0.017
cellular response to decreased oxygen levels GO:0036294 1 0.017
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.017
response to topologically incorrect protein GO:0035966 2 0.017
regulation of ion transmembrane transporter activity GO:0032412 2 0.017
tube morphogenesis GO:0035239 349 0.017
camera type eye morphogenesis GO:0048593 108 0.017
pigment granule transport GO:0051904 19 0.017
chemosensory behavior GO:0007635 1 0.017
regulation of protein complex assembly GO:0043254 3 0.017
positive regulation of protein complex assembly GO:0031334 2 0.017
macromolecular complex subunit organization GO:0043933 74 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.016
organic cyclic compound biosynthetic process GO:1901362 223 0.016
positive regulation of neuron death GO:1901216 1 0.016
cellular hormone metabolic process GO:0034754 19 0.016
system process GO:0003008 185 0.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.016
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.016
regulation of reproductive process GO:2000241 4 0.016
nephron tubule morphogenesis GO:0072078 1 0.016
regulation of synapse assembly GO:0051963 3 0.016
homeostatic process GO:0042592 142 0.016
rna localization GO:0006403 4 0.016
adult behavior GO:0030534 2 0.016
protein complex disassembly GO:0043241 1 0.016
neuron neuron synaptic transmission GO:0007270 1 0.016
regulation of purine nucleotide catabolic process GO:0033121 2 0.016
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.016
positive regulation of biological process GO:0048518 253 0.016
regulation of cyclase activity GO:0031279 12 0.015
positive regulation of secretion GO:0051047 1 0.015
wnt signaling pathway GO:0016055 80 0.015
tube closure GO:0060606 1 0.015
cellular catabolic process GO:0044248 27 0.015
neuron development GO:0048666 262 0.015
regulation of cell activation GO:0050865 1 0.015
negative regulation of synapse assembly GO:0051964 2 0.015
pancreas development GO:0031016 84 0.015
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.015
positive regulation of cellular component biogenesis GO:0044089 3 0.015
response to uv GO:0009411 3 0.015
g2 dna damage checkpoint GO:0031572 3 0.015
biosynthetic process GO:0009058 294 0.015
small gtpase mediated signal transduction GO:0007264 8 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
regulation of synaptic plasticity GO:0048167 1 0.015
negative regulation of map kinase activity GO:0043407 2 0.015
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.015
cellular response to chemical stimulus GO:0070887 157 0.015
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.015
synaptic vesicle localization GO:0097479 1 0.015
neuron differentiation GO:0030182 353 0.015
stem cell maintenance GO:0019827 4 0.015
positive regulation of cytoskeleton organization GO:0051495 3 0.015
striated muscle cell development GO:0055002 108 0.015
nuclear export GO:0051168 1 0.015
embryo development ending in birth or egg hatching GO:0009792 271 0.015
macromolecular complex disassembly GO:0032984 1 0.015
regulation of meiotic cell cycle GO:0051445 1 0.015
neuron projection guidance GO:0097485 86 0.015
primary neural tube formation GO:0014020 1 0.015
developmental programmed cell death GO:0010623 4 0.015
negative regulation of leukocyte differentiation GO:1902106 1 0.015
nucleic acid metabolic process GO:0090304 244 0.015
ion transport GO:0006811 114 0.015
regulation of cellular response to growth factor stimulus GO:0090287 35 0.014
smooth muscle tissue development GO:0048745 1 0.014
heart morphogenesis GO:0003007 156 0.014
protein localization to plasma membrane GO:0072659 1 0.014
transcription dna templated GO:0006351 181 0.014
aromatic compound biosynthetic process GO:0019438 217 0.014
regulation of protein ubiquitination GO:0031396 3 0.014
ribonucleoside monophosphate catabolic process GO:0009158 4 0.014
g1 s transition of mitotic cell cycle GO:0000082 1 0.014
positive regulation of cell activation GO:0050867 1 0.014
regulation of membrane potential GO:0042391 23 0.014
regulation of cytokine production GO:0001817 3 0.014
regulation of vasculature development GO:1901342 33 0.014
sympathetic nervous system development GO:0048485 3 0.014
regulation of signal transduction GO:0009966 225 0.014
production of molecular mediator of immune response GO:0002440 2 0.014
regulation of establishment of protein localization GO:0070201 4 0.014
axonogenesis GO:0007409 152 0.014
golgi organization GO:0007030 1 0.014
protein complex biogenesis GO:0070271 30 0.014
lateral line system development GO:0048925 76 0.014
glycerolipid biosynthetic process GO:0045017 1 0.014
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.014
macroautophagy GO:0016236 1 0.014
neural tube patterning GO:0021532 33 0.014
enzyme linked receptor protein signaling pathway GO:0007167 106 0.014
extracellular matrix organization GO:0030198 27 0.014
neuron apoptotic process GO:0051402 20 0.013
antimicrobial humoral response GO:0019730 2 0.013
mesenchyme development GO:0060485 127 0.013
protein polymerization GO:0051258 4 0.013
microtubule depolymerization GO:0007019 1 0.013
renal system process GO:0003014 14 0.013
leukocyte homeostasis GO:0001776 2 0.013
positive regulation of stress activated mapk cascade GO:0032874 3 0.013
leukocyte differentiation GO:0002521 25 0.013
establishment of pigment granule localization GO:0051905 22 0.013
extracellular structure organization GO:0043062 27 0.013
regulation of neurogenesis GO:0050767 87 0.013
negative regulation of autophagy GO:0010507 1 0.013
microtubule polymerization or depolymerization GO:0031109 3 0.013
transmembrane transport GO:0055085 120 0.013
oligodendrocyte differentiation GO:0048709 23 0.013
cellular protein complex disassembly GO:0043624 1 0.013
regulation of blood vessel size GO:0050880 2 0.013
appendage morphogenesis GO:0035107 56 0.013
tissue remodeling GO:0048771 4 0.013
establishment of synaptic vesicle localization GO:0097480 1 0.013
response to organic substance GO:0010033 153 0.013
renal tubule morphogenesis GO:0061333 1 0.013
phosphatidylinositol mediated signaling GO:0048015 2 0.013
mesenchymal cell development GO:0014031 78 0.013
regulation of gene expression GO:0010468 265 0.013
fin development GO:0033333 77 0.012
cellular localization GO:0051641 97 0.012
cellular component assembly involved in morphogenesis GO:0010927 107 0.012
regulation of neuronal synaptic plasticity GO:0048168 1 0.012
regulation of protein localization to nucleus GO:1900180 2 0.012
cellular macromolecule biosynthetic process GO:0034645 224 0.012
neuron projection morphogenesis GO:0048812 161 0.012
regulation of nervous system development GO:0051960 90 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
muscle cell differentiation GO:0042692 139 0.012
nucleobase containing small molecule metabolic process GO:0055086 32 0.012
positive regulation of map kinase activity GO:0043406 3 0.012
regulation of tissue remodeling GO:0034103 2 0.012
wound healing GO:0042060 90 0.012
synaptic vesicle transport GO:0048489 1 0.012
sprouting angiogenesis GO:0002040 53 0.012
internal protein amino acid acetylation GO:0006475 2 0.012
regulation of organ growth GO:0046620 3 0.012
hepaticobiliary system development GO:0061008 98 0.012
cellular amide metabolic process GO:0043603 4 0.012
regulation of apoptotic process GO:0042981 98 0.012
axonal defasciculation GO:0007414 2 0.012
protein depolymerization GO:0051261 1 0.012
leukocyte proliferation GO:0070661 1 0.012
odontogenesis of dentin containing tooth GO:0042475 1 0.012
peptidyl threonine phosphorylation GO:0018107 1 0.012
peptidyl serine modification GO:0018209 2 0.012
regulation of dna replication GO:0006275 3 0.012
oxidative phosphorylation GO:0006119 1 0.012
cell killing GO:0001906 2 0.012
regulation of transmembrane transporter activity GO:0022898 2 0.012
positive regulation of myeloid cell differentiation GO:0045639 2 0.012
cytokinesis GO:0000910 3 0.012
regulation of signaling GO:0023051 235 0.012
purine nucleoside monophosphate catabolic process GO:0009128 4 0.012
sleep GO:0030431 1 0.011
regulation of cell development GO:0060284 100 0.011
organic substance transport GO:0071702 58 0.011
cell substrate adherens junction assembly GO:0007045 1 0.011
cell cycle arrest GO:0007050 1 0.011
melanosome localization GO:0032400 21 0.011
regulation of transporter activity GO:0032409 2 0.011
peptidyl serine phosphorylation GO:0018105 1 0.011
camera type eye development GO:0043010 222 0.011
neuronal action potential GO:0019228 18 0.011
fin morphogenesis GO:0033334 53 0.011
positive regulation of histone modification GO:0031058 1 0.011
positive regulation of translation GO:0045727 1 0.011
negative regulation of cellular catabolic process GO:0031330 3 0.011
cellular nitrogen compound biosynthetic process GO:0044271 218 0.011
positive regulation of cellular metabolic process GO:0031325 94 0.011
regulation of gtpase activity GO:0043087 2 0.011
centrosome cycle GO:0007098 1 0.011
b cell activation GO:0042113 2 0.011
retina layer formation GO:0010842 24 0.011
sensory system development GO:0048880 76 0.011
regulation of bone remodeling GO:0046850 2 0.011
negative regulation of chromosome organization GO:2001251 1 0.011
positive regulation of lyase activity GO:0051349 6 0.011
regulation of histone methylation GO:0031060 3 0.011
mesenchymal cell differentiation GO:0048762 87 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.011
actin filament polymerization GO:0030041 2 0.011
negative regulation of neural precursor cell proliferation GO:2000178 1 0.011
rna metabolic process GO:0016070 219 0.011
dorsal ventral pattern formation GO:0009953 125 0.011
gland development GO:0048732 143 0.011
organonitrogen compound metabolic process GO:1901564 74 0.011
chromosome organization GO:0051276 31 0.011
organophosphate metabolic process GO:0019637 37 0.011
regulation of cell projection assembly GO:0060491 4 0.011
myofibril assembly GO:0030239 48 0.011
regulation of neurotransmitter transport GO:0051588 1 0.011
regulation of rho protein signal transduction GO:0035023 2 0.011
actin cytoskeleton organization GO:0030036 63 0.011
embryonic hemopoiesis GO:0035162 53 0.011
exocytosis GO:0006887 1 0.011
thermosensory behavior GO:0040040 1 0.011
regulation of reactive oxygen species metabolic process GO:2000377 2 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
cellular biogenic amine metabolic process GO:0006576 2 0.011

tsc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.063
cardiovascular system disease DOID:1287 0 0.063
disease of cellular proliferation DOID:14566 0 0.031
nervous system disease DOID:863 0 0.020
musculoskeletal system disease DOID:17 0 0.017
myopathy DOID:423 0 0.016
muscular disease DOID:0080000 0 0.016
muscle tissue disease DOID:66 0 0.016
cancer DOID:162 0 0.013
organ system cancer DOID:0050686 0 0.012
disease of metabolism DOID:0014667 0 0.011
heart disease DOID:114 0 0.011
inherited metabolic disorder DOID:655 0 0.011
immune system disease DOID:2914 0 0.011