Danio rerio

0 known processes

ttc25

tetratricopeptide repeat domain 25

(Aliases: MGC56362,zgc:56362)

ttc25 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
meiotic cell cycle process GO:1903046 3 0.162
meiotic nuclear division GO:0007126 4 0.131
negative regulation of biological process GO:0048519 304 0.119
spindle assembly GO:0051225 2 0.111
aging GO:0007568 2 0.105
epithelial cilium movement GO:0003351 15 0.094
heart development GO:0007507 313 0.084
tube morphogenesis GO:0035239 349 0.082
digestive system development GO:0055123 289 0.072
regulation of muscle contraction GO:0006937 3 0.071
regulation of signal transduction GO:0009966 225 0.050
epithelial cilium movement involved in determination of left right asymmetry GO:0060287 8 0.046
cytokinesis GO:0000910 3 0.046
regulation of cell communication GO:0010646 232 0.045
signal transduction GO:0007165 455 0.044
negative regulation of gene expression GO:0010629 65 0.044
larval development GO:0002164 2 0.043
negative regulation of cellular process GO:0048523 283 0.041
organelle organization GO:0006996 227 0.039
regulation of cytokine production GO:0001817 3 0.039
cellular aromatic compound metabolic process GO:0006725 295 0.038
maintenance of location GO:0051235 4 0.038
regulation of cardiac muscle contraction GO:0055117 2 0.038
ribonucleoside monophosphate catabolic process GO:0009158 4 0.038
ear morphogenesis GO:0042471 64 0.037
release of sequestered calcium ion into cytosol GO:0051209 3 0.036
positive regulation of catabolic process GO:0009896 4 0.035
regulation of response to stimulus GO:0048583 269 0.034
positive regulation of transport GO:0051050 2 0.034
gene expression GO:0010467 252 0.033
positive regulation of translation GO:0045727 1 0.032
determination of bilateral symmetry GO:0009855 204 0.032
organelle localization GO:0051640 49 0.031
cilium morphogenesis GO:0060271 85 0.031
sensory organ morphogenesis GO:0090596 200 0.031
female meiotic division GO:0007143 2 0.031
cellular component morphogenesis GO:0032989 336 0.031
spermatid development GO:0007286 2 0.029
stem cell maintenance GO:0019827 4 0.029
regulation of protein ubiquitination GO:0031396 3 0.029
embryonic organ development GO:0048568 381 0.028
amine metabolic process GO:0009308 2 0.028
somatic stem cell maintenance GO:0035019 1 0.027
positive regulation of biological process GO:0048518 253 0.027
cation transport GO:0006812 81 0.027
mitotic dna integrity checkpoint GO:0044774 4 0.027
regulation of cellular amine metabolic process GO:0033238 0 0.026
epithelial tube morphogenesis GO:0060562 148 0.026
ectodermal placode formation GO:0060788 26 0.025
cilium movement GO:0003341 26 0.025
cell morphogenesis GO:0000902 289 0.025
regulation of cellular amino acid metabolic process GO:0006521 0 0.025
circulatory system process GO:0003013 87 0.025
negative regulation of cell death GO:0060548 60 0.025
rna metabolic process GO:0016070 219 0.024
cellular nitrogen compound metabolic process GO:0034641 290 0.024
lipid storage GO:0019915 1 0.024
positive regulation of cellular component biogenesis GO:0044089 3 0.024
protein complex disassembly GO:0043241 1 0.024
cell proliferation GO:0008283 80 0.024
nephron epithelium morphogenesis GO:0072088 1 0.024
nitrogen compound metabolic process GO:0006807 319 0.024
regulation of reactive oxygen species metabolic process GO:2000377 2 0.024
morphogenesis of an epithelium GO:0002009 333 0.024
response to stress GO:0006950 263 0.024
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.023
embryonic organ morphogenesis GO:0048562 274 0.023
negative regulation of kinase activity GO:0033673 4 0.023
cellular component disassembly GO:0022411 1 0.023
renal tubule morphogenesis GO:0061333 1 0.023
regulation of metal ion transport GO:0010959 4 0.023
ion transport GO:0006811 114 0.023
regulation of metabolic process GO:0019222 359 0.022
protein metabolic process GO:0019538 183 0.022
germ line stem cell maintenance GO:0030718 2 0.022
regulation of cellular metabolic process GO:0031323 320 0.022
cellular response to xenobiotic stimulus GO:0071466 35 0.022
blood vessel development GO:0001568 246 0.021
cellular component biogenesis GO:0044085 178 0.021
heterocycle metabolic process GO:0046483 290 0.021
cellular protein metabolic process GO:0044267 129 0.021
regulation of microtubule based movement GO:0060632 3 0.020
lymphocyte proliferation GO:0046651 1 0.020
oxoacid metabolic process GO:0043436 31 0.020
regulation of cell shape GO:0008360 1 0.020
mitotic cell cycle GO:0000278 64 0.020
regulation of ion transmembrane transporter activity GO:0032412 2 0.020
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.019
system process GO:0003008 185 0.019
regulation of cell activation GO:0050865 1 0.019
negative regulation of dna replication GO:0008156 2 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.019
amino acid transport GO:0006865 2 0.019
response to monosaccharide GO:0034284 3 0.019
sensory organ development GO:0007423 393 0.019
mitotic cell cycle process GO:1903047 48 0.018
cellular component movement GO:0006928 335 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
single organism organelle organization GO:1902589 199 0.018
cell surface receptor signaling pathway GO:0007166 325 0.018
organonitrogen compound metabolic process GO:1901564 74 0.018
nucleobase containing compound metabolic process GO:0006139 274 0.018
embryonic heart tube development GO:0035050 133 0.018
cellular macromolecule metabolic process GO:0044260 391 0.018
response to chemical GO:0042221 320 0.018
alternative mrna splicing via spliceosome GO:0000380 1 0.018
response to organic substance GO:0010033 153 0.018
regulation of hormone secretion GO:0046883 2 0.018
sequestering of metal ion GO:0051238 3 0.018
regulation of cell differentiation GO:0045595 142 0.018
regulation of striated muscle contraction GO:0006942 2 0.018
female sex differentiation GO:0046660 4 0.018
muscle contraction GO:0006936 18 0.018
negative regulation of sequestering of calcium ion GO:0051283 4 0.017
regulation of mrna processing GO:0050684 3 0.017
nephron morphogenesis GO:0072028 2 0.017
spermatid differentiation GO:0048515 2 0.017
dicarboxylic acid transport GO:0006835 1 0.017
meiotic spindle organization GO:0000212 1 0.017
cellular localization GO:0051641 97 0.017
aromatic compound biosynthetic process GO:0019438 217 0.017
determination of heart left right asymmetry GO:0061371 117 0.017
liver development GO:0001889 96 0.017
modification dependent macromolecule catabolic process GO:0043632 3 0.017
response to hexose GO:0009746 3 0.017
transport GO:0006810 220 0.017
cellular response to external stimulus GO:0071496 2 0.016
development of primary female sexual characteristics GO:0046545 4 0.016
regulation of protein catabolic process GO:0042176 1 0.016
blood circulation GO:0008015 87 0.016
organelle assembly GO:0070925 110 0.016
cellular ketone metabolic process GO:0042180 11 0.016
negative regulation of protein phosphorylation GO:0001933 4 0.016
cellular amine metabolic process GO:0044106 2 0.016
regulation of cellular protein metabolic process GO:0032268 52 0.016
positive regulation of embryonic development GO:0040019 3 0.016
nuclear division GO:0000280 23 0.016
embryo development ending in birth or egg hatching GO:0009792 271 0.016
ear development GO:0043583 127 0.016
meiotic chromosome segregation GO:0045132 3 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.016
sodium ion transmembrane transport GO:0035725 21 0.016
regulation of signaling GO:0023051 235 0.016
regulation of tube size GO:0035150 2 0.016
long chain fatty acid metabolic process GO:0001676 1 0.016
intracellular signal transduction GO:0035556 85 0.016
cytoskeleton dependent cytokinesis GO:0061640 3 0.016
regulation of mrna splicing via spliceosome GO:0048024 3 0.015
cell projection organization GO:0030030 284 0.015
nucleocytoplasmic transport GO:0006913 4 0.015
regulation of programmed cell death GO:0043067 101 0.015
macromolecular complex subunit organization GO:0043933 74 0.015
gland development GO:0048732 143 0.015
actin filament based movement GO:0030048 1 0.015
small gtpase mediated signal transduction GO:0007264 8 0.015
single organism localization GO:1902578 225 0.015
regulation of cell cycle process GO:0010564 20 0.015
cell cycle arrest GO:0007050 1 0.015
regulation of transporter activity GO:0032409 2 0.015
epithelial cell morphogenesis GO:0003382 2 0.015
mrna metabolic process GO:0016071 20 0.015
regulation of multicellular organism growth GO:0040014 4 0.014
female gonad development GO:0008585 4 0.014
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.014
b cell activation GO:0042113 2 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.014
negative regulation of stem cell differentiation GO:2000737 2 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.014
regulation of stem cell differentiation GO:2000736 4 0.014
regulation of anatomical structure size GO:0090066 33 0.014
cell cycle process GO:0022402 53 0.014
adult behavior GO:0030534 2 0.014
cell part morphogenesis GO:0032990 246 0.014
regulation of apoptotic process GO:0042981 98 0.014
guanosine containing compound metabolic process GO:1901068 4 0.014
ectodermal placode development GO:0071696 37 0.014
response to carbohydrate GO:0009743 3 0.014
positive regulation of cellular metabolic process GO:0031325 94 0.014
negative regulation of macromolecule metabolic process GO:0010605 76 0.014
microtubule based process GO:0007017 60 0.013
response to xenobiotic stimulus GO:0009410 45 0.013
inner ear morphogenesis GO:0042472 63 0.013
chromosome segregation GO:0007059 12 0.013
rna biosynthetic process GO:0032774 181 0.013
regulation of dna replication GO:0006275 3 0.013
regulation of cellular biosynthetic process GO:0031326 245 0.013
regulation of gtpase activity GO:0043087 2 0.013
cellular modified amino acid metabolic process GO:0006575 3 0.013
negative regulation of rna biosynthetic process GO:1902679 45 0.013
positive regulation of map kinase activity GO:0043406 3 0.013
establishment of localization GO:0051234 244 0.013
positive regulation of gtpase activity GO:0043547 1 0.013
regionalization GO:0003002 274 0.013
cellular response to chemical stimulus GO:0070887 157 0.013
cellular response to unfolded protein GO:0034620 2 0.013
response to inorganic substance GO:0010035 38 0.013
regulation of macromolecule metabolic process GO:0060255 317 0.013
lipid homeostasis GO:0055088 3 0.013
organic acid metabolic process GO:0006082 31 0.013
toll like receptor signaling pathway GO:0002224 4 0.013
gastrulation GO:0007369 208 0.013
hormone secretion GO:0046879 2 0.013
regulation of cell death GO:0010941 103 0.013
regulation of gtp catabolic process GO:0033124 2 0.012
specification of axis polarity GO:0065001 4 0.012
negative regulation of dna metabolic process GO:0051053 4 0.012
cytoskeleton organization GO:0007010 96 0.012
cellular component assembly GO:0022607 170 0.012
regulation of establishment of protein localization GO:0070201 4 0.012
digestive tract morphogenesis GO:0048546 231 0.012
negative regulation of rna metabolic process GO:0051253 48 0.012
regulation of protein transport GO:0051223 3 0.012
cognition GO:0050890 1 0.012
regulation of protein metabolic process GO:0051246 56 0.012
muscle structure development GO:0061061 196 0.012
response to glucose GO:0009749 3 0.012
hormone transport GO:0009914 2 0.012
small molecule metabolic process GO:0044281 77 0.012
response to drug GO:0042493 3 0.012
cell death GO:0008219 121 0.012
positive regulation of cellular catabolic process GO:0031331 3 0.012
mitotic nuclear division GO:0007067 18 0.012
regulation of sequestering of calcium ion GO:0051282 4 0.012
multicellular organism growth GO:0035264 4 0.012
tube formation GO:0035148 25 0.012
carboxylic acid metabolic process GO:0019752 22 0.012
regulation of calcium ion transport GO:0051924 2 0.012
regulation of transmembrane transporter activity GO:0022898 2 0.011
regulation of blood pressure GO:0008217 1 0.011
smoothened signaling pathway GO:0007224 30 0.011
immunoglobulin mediated immune response GO:0016064 3 0.011
cellular amino acid metabolic process GO:0006520 7 0.011
cellular response to organic substance GO:0071310 105 0.011
heart looping GO:0001947 94 0.011
response to lipid GO:0033993 60 0.011
rna export from nucleus GO:0006405 1 0.011
transmission of nerve impulse GO:0019226 19 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
cellular nitrogen compound biosynthetic process GO:0044271 218 0.011
positive regulation of cell cycle GO:0045787 3 0.011
microtubule organizing center organization GO:0031023 1 0.011
ras protein signal transduction GO:0007265 7 0.011
nucleoside monophosphate catabolic process GO:0009125 4 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.011
post golgi vesicle mediated transport GO:0006892 1 0.011
centrosome organization GO:0051297 1 0.011
negative regulation of molecular function GO:0044092 23 0.011
cellular protein modification process GO:0006464 100 0.011
regulation of nitrogen compound metabolic process GO:0051171 251 0.011
negative regulation of signal transduction GO:0009968 94 0.011
organic cyclic compound metabolic process GO:1901360 301 0.011
positive regulation of reproductive process GO:2000243 2 0.011
regulation of blood vessel size GO:0050880 2 0.011
regulation of circadian rhythm GO:0042752 4 0.010
macromolecule modification GO:0043412 111 0.010
regulation of cellular component organization GO:0051128 86 0.010
venous endothelial cell migration involved in lymph vessel development GO:0060855 4 0.010
positive regulation of metabolic process GO:0009893 108 0.010
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.010
negative regulation of cell communication GO:0010648 96 0.010
multi organism process GO:0051704 134 0.010
death GO:0016265 121 0.010
negative regulation of metabolic process GO:0009892 86 0.010
negative regulation of biosynthetic process GO:0009890 55 0.010
nephron tubule morphogenesis GO:0072078 1 0.010
neurological system process GO:0050877 62 0.010
regulation of rna metabolic process GO:0051252 224 0.010
cerebellum formation GO:0021588 2 0.010
purine nucleoside monophosphate catabolic process GO:0009128 4 0.010
organelle fission GO:0048285 23 0.010
establishment of protein localization to organelle GO:0072594 4 0.010
response to oxygen containing compound GO:1901700 55 0.010
regulation of cell projection assembly GO:0060491 4 0.010

ttc25 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.052
disease of cellular proliferation DOID:14566 0 0.011
cancer DOID:162 0 0.011
organ system cancer DOID:0050686 0 0.011
hematopoietic system disease DOID:74 0 0.010
immune system disease DOID:2914 0 0.010