Danio rerio

0 known processes

tube1

tubulin, epsilon 1

(Aliases: MGC63582,zgc:63582)

tube1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cilium morphogenesis GO:0060271 85 0.213
signal transduction GO:0007165 455 0.110
epithelial cilium movement GO:0003351 15 0.110
smoothened signaling pathway GO:0007224 30 0.106
urogenital system development GO:0001655 97 0.104
tube morphogenesis GO:0035239 349 0.083
meiotic nuclear division GO:0007126 4 0.080
regulation of developmental process GO:0050793 247 0.079
microtubule based movement GO:0007018 33 0.071
regulation of establishment of protein localization GO:0070201 4 0.064
aging GO:0007568 2 0.063
regulation of oligodendrocyte differentiation GO:0048713 1 0.062
positive regulation of transport GO:0051050 2 0.062
nuclear import GO:0051170 3 0.061
regulation of cytokine production GO:0001817 3 0.060
transport GO:0006810 220 0.058
regulation of cell communication GO:0010646 232 0.057
establishment of endothelial barrier GO:0061028 3 0.055
single organism metabolic process GO:0044710 217 0.053
larval development GO:0002164 2 0.051
maintenance of location GO:0051235 4 0.051
regulation of protein transport GO:0051223 3 0.050
regulation of response to stimulus GO:0048583 269 0.047
cilium movement GO:0003341 26 0.047
cognition GO:0050890 1 0.045
regulation of metabolic process GO:0019222 359 0.044
digestive system development GO:0055123 289 0.044
nephron tubule morphogenesis GO:0072078 1 0.043
regulation of nucleotide catabolic process GO:0030811 2 0.043
guanosine containing compound metabolic process GO:1901068 4 0.042
gtp catabolic process GO:0006184 2 0.041
heterocycle metabolic process GO:0046483 290 0.041
nucleocytoplasmic transport GO:0006913 4 0.041
renal tubule morphogenesis GO:0061333 1 0.038
positive regulation of cellular catabolic process GO:0031331 3 0.038
regulation of signaling GO:0023051 235 0.037
epithelial cilium movement involved in determination of left right asymmetry GO:0060287 8 0.037
epithelial tube morphogenesis GO:0060562 148 0.037
negative regulation of kinase activity GO:0033673 4 0.037
regulation of nucleoside metabolic process GO:0009118 2 0.036
cellular localization GO:0051641 97 0.036
negative regulation of gliogenesis GO:0014014 1 0.036
negative regulation of cellular process GO:0048523 283 0.036
regulation of cell shape GO:0008360 1 0.035
regulation of gtp catabolic process GO:0033124 2 0.034
regulation of glial cell differentiation GO:0045685 4 0.034
response to chemical GO:0042221 320 0.034
cellular nitrogen compound metabolic process GO:0034641 290 0.033
lipid storage GO:0019915 1 0.033
regulation of purine nucleotide catabolic process GO:0033121 2 0.033
positive regulation of translation GO:0045727 1 0.033
small molecule metabolic process GO:0044281 77 0.033
regulation of stem cell differentiation GO:2000736 4 0.033
single organism localization GO:1902578 225 0.033
cell morphogenesis GO:0000902 289 0.032
hormone secretion GO:0046879 2 0.032
nitrogen compound metabolic process GO:0006807 319 0.031
negative regulation of biological process GO:0048519 304 0.031
regulation of dna replication GO:0006275 3 0.031
alternative mrna splicing via spliceosome GO:0000380 1 0.030
b cell activation GO:0042113 2 0.030
single organism nuclear import GO:1902593 3 0.029
positive regulation of catabolic process GO:0009896 4 0.029
gastrulation GO:0007369 208 0.029
stem cell maintenance GO:0019827 4 0.029
cellular macromolecule metabolic process GO:0044260 391 0.029
leukocyte proliferation GO:0070661 1 0.029
gtp metabolic process GO:0046039 4 0.029
nuclear export GO:0051168 1 0.028
establishment of protein localization to organelle GO:0072594 4 0.028
positive regulation of metabolic process GO:0009893 108 0.028
positive regulation of cell cycle GO:0045787 3 0.028
cellular aromatic compound metabolic process GO:0006725 295 0.028
lymphocyte proliferation GO:0046651 1 0.027
protein metabolic process GO:0019538 183 0.027
embryo development ending in birth or egg hatching GO:0009792 271 0.027
nuclear transport GO:0051169 4 0.026
intracellular signal transduction GO:0035556 85 0.026
small gtpase mediated signal transduction GO:0007264 8 0.025
guanosine containing compound catabolic process GO:1901069 2 0.025
regulation of rho protein signal transduction GO:0035023 2 0.025
single organism transport GO:0044765 206 0.025
organic cyclic compound metabolic process GO:1901360 301 0.025
cellular component morphogenesis GO:0032989 336 0.025
regulation of cellular metabolic process GO:0031323 320 0.025
cellular macromolecule biosynthetic process GO:0034645 224 0.025
organelle fission GO:0048285 23 0.024
response to organic substance GO:0010033 153 0.024
negative regulation of signal transduction GO:0009968 94 0.024
meiotic cell cycle process GO:1903046 3 0.024
heart development GO:0007507 313 0.024
toll like receptor signaling pathway GO:0002224 4 0.024
multicellular organismal signaling GO:0035637 22 0.023
negative regulation of protein phosphorylation GO:0001933 4 0.023
cell projection organization GO:0030030 284 0.023
modification dependent protein catabolic process GO:0019941 3 0.023
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.023
regulation of cell differentiation GO:0045595 142 0.023
morphogenesis of an epithelium GO:0002009 333 0.023
chordate embryonic development GO:0043009 271 0.022
regulation of gtpase activity GO:0043087 2 0.022
response to stress GO:0006950 263 0.022
protein modification process GO:0036211 100 0.022
regulation of primary metabolic process GO:0080090 311 0.022
cellular component disassembly GO:0022411 1 0.022
regulation of signal transduction GO:0009966 225 0.022
negative regulation of metabolic process GO:0009892 86 0.022
spermatid development GO:0007286 2 0.022
response to oxygen containing compound GO:1901700 55 0.022
negative regulation of stem cell differentiation GO:2000737 2 0.022
regulation of protein targeting GO:1903533 2 0.021
female meiotic division GO:0007143 2 0.021
regulation of cytoplasmic transport GO:1903649 4 0.021
liver development GO:0001889 96 0.021
oxoacid metabolic process GO:0043436 31 0.021
regulation of cell activation GO:0050865 1 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
ras protein signal transduction GO:0007265 7 0.020
negative regulation of protein kinase activity GO:0006469 4 0.020
nucleobase containing compound metabolic process GO:0006139 274 0.020
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.020
transmission of nerve impulse GO:0019226 19 0.020
protein complex disassembly GO:0043241 1 0.020
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 1 0.020
gene expression GO:0010467 252 0.020
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.020
negative regulation of protein transport GO:0051224 3 0.020
regulation of cellular ketone metabolic process GO:0010565 7 0.020
organic substance transport GO:0071702 58 0.019
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.019
positive regulation of gtp catabolic process GO:0033126 1 0.019
regulation of macromolecule metabolic process GO:0060255 317 0.019
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.019
protein import into nucleus GO:0006606 3 0.019
peptide transport GO:0015833 1 0.019
negative regulation of ras protein signal transduction GO:0046580 1 0.019
cell surface receptor signaling pathway GO:0007166 325 0.019
regulation of leukocyte mediated immunity GO:0002703 1 0.019
specification of symmetry GO:0009799 204 0.019
protein acetylation GO:0006473 2 0.019
regulation of cellular amine metabolic process GO:0033238 0 0.018
positive regulation of secretion GO:0051047 1 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.018
positive regulation of gtpase activity GO:0043547 1 0.018
establishment of localization in cell GO:0051649 77 0.018
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.018
macromolecular complex subunit organization GO:0043933 74 0.018
cell part morphogenesis GO:0032990 246 0.018
cellular amine metabolic process GO:0044106 2 0.018
embryonic organ morphogenesis GO:0048562 274 0.018
immunoglobulin mediated immune response GO:0016064 3 0.018
modification dependent macromolecule catabolic process GO:0043632 3 0.018
mononuclear cell proliferation GO:0032943 1 0.018
organic acid metabolic process GO:0006082 31 0.018
gliogenesis GO:0042063 45 0.018
cellular ketone metabolic process GO:0042180 11 0.017
renal system development GO:0072001 94 0.017
cellular nitrogen compound biosynthetic process GO:0044271 218 0.017
regulation of nucleocytoplasmic transport GO:0046822 2 0.017
multicellular organism growth GO:0035264 4 0.017
regulation of protein localization to nucleus GO:1900180 2 0.017
regulation of mrna processing GO:0050684 3 0.017
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.017
positive regulation of biological process GO:0048518 253 0.017
establishment of localization GO:0051234 244 0.017
centrosome organization GO:0051297 1 0.017
negative regulation of cytokine production GO:0001818 1 0.017
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.017
spermatid differentiation GO:0048515 2 0.017
regulation of neural precursor cell proliferation GO:2000177 3 0.017
regulation of receptor activity GO:0010469 2 0.017
somatic stem cell maintenance GO:0035019 1 0.017
regulation of cellular biosynthetic process GO:0031326 245 0.016
response to carbohydrate GO:0009743 3 0.016
positive regulation of nucleoside metabolic process GO:0045979 1 0.016
amino acid transport GO:0006865 2 0.016
macromolecular complex disassembly GO:0032984 1 0.016
negative regulation of dna metabolic process GO:0051053 4 0.016
internal protein amino acid acetylation GO:0006475 2 0.016
regulation of cell substrate adhesion GO:0010810 1 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.016
cilium organization GO:0044782 71 0.016
macromolecule modification GO:0043412 111 0.016
regulation of intracellular signal transduction GO:1902531 57 0.016
protein secretion GO:0009306 1 0.016
organonitrogen compound metabolic process GO:1901564 74 0.016
organelle organization GO:0006996 227 0.016
determination of liver left right asymmetry GO:0071910 11 0.016
ensheathment of neurons GO:0007272 18 0.015
regulation of molecular function GO:0065009 70 0.015
microtubule organizing center organization GO:0031023 1 0.015
digestive tract morphogenesis GO:0048546 231 0.015
embryonic organ development GO:0048568 381 0.015
cell cycle GO:0007049 93 0.015
nephron morphogenesis GO:0072028 2 0.015
regulation of protein catabolic process GO:0042176 1 0.015
nitrogen compound transport GO:0071705 23 0.015
cellular protein catabolic process GO:0044257 4 0.015
internal peptidyl lysine acetylation GO:0018393 2 0.015
positive regulation of cellular component biogenesis GO:0044089 3 0.015
regulation of intracellular protein transport GO:0033157 3 0.015
protein import GO:0017038 3 0.014
regulation of cell development GO:0060284 100 0.014
regulation of muscle contraction GO:0006937 3 0.014
cellular protein modification process GO:0006464 100 0.014
neuronal action potential GO:0019228 18 0.014
response to amino acid GO:0043200 2 0.014
protein targeting to nucleus GO:0044744 3 0.014
female gonad development GO:0008585 4 0.014
regulation of hormone secretion GO:0046883 2 0.014
regulation of protein import into nucleus GO:0042306 2 0.014
transcription from rna polymerase ii promoter GO:0006366 80 0.014
regulation of smoothened signaling pathway GO:0008589 18 0.014
nucleic acid templated transcription GO:0097659 181 0.014
cytokinesis GO:0000910 3 0.013
cell cycle arrest GO:0007050 1 0.013
regulation of tube size GO:0035150 2 0.013
innate immune response activating signal transduction GO:0002758 5 0.013
regulation of transporter activity GO:0032409 2 0.013
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.013
action potential GO:0001508 19 0.013
negative regulation of macromolecule metabolic process GO:0010605 76 0.013
regulation of biosynthetic process GO:0009889 250 0.013
b cell mediated immunity GO:0019724 3 0.013
negative regulation of signaling GO:0023057 96 0.013
kidney development GO:0001822 92 0.013
rna transport GO:0050658 2 0.013
negative regulation of secretion by cell GO:1903531 2 0.013
regulation of multicellular organismal development GO:2000026 223 0.013
positive regulation of jnk cascade GO:0046330 3 0.013
determination of bilateral symmetry GO:0009855 204 0.013
development of primary female sexual characteristics GO:0046545 4 0.013
regulation of mrna splicing via spliceosome GO:0048024 3 0.013
rna localization GO:0006403 4 0.013
regulation of microtubule cytoskeleton organization GO:0070507 3 0.012
regulation of cellular protein metabolic process GO:0032268 52 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.012
regulation of cell matrix adhesion GO:0001952 1 0.012
macromolecular complex assembly GO:0065003 35 0.012
cytoskeleton dependent cytokinesis GO:0061640 3 0.012
g2 m transition of mitotic cell cycle GO:0000086 4 0.012
phosphate containing compound metabolic process GO:0006796 108 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
negative regulation of cell communication GO:0010648 96 0.012
transmembrane transport GO:0055085 120 0.012
female sex differentiation GO:0046660 4 0.012
regulation of cardiac muscle contraction GO:0055117 2 0.012
release of sequestered calcium ion into cytosol GO:0051209 3 0.012
meiotic spindle organization GO:0000212 1 0.012
mitotic dna damage checkpoint GO:0044773 4 0.012
regulation of catalytic activity GO:0050790 55 0.012
regulation of ras gtpase activity GO:0032318 2 0.012
anion transport GO:0006820 38 0.012
negative regulation of response to stimulus GO:0048585 104 0.012
single organism organelle organization GO:1902589 199 0.012
negative regulation of developmental process GO:0051093 65 0.011
cellular amino acid metabolic process GO:0006520 7 0.011
organic cyclic compound biosynthetic process GO:1901362 223 0.011
regulation of protein metabolic process GO:0051246 56 0.011
nitric oxide metabolic process GO:0046209 2 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
positive regulation of cyclin dependent protein serine threonine kinase activity GO:0045737 1 0.011
cellular protein metabolic process GO:0044267 129 0.011
cell proliferation GO:0008283 80 0.011
nucleobase containing compound biosynthetic process GO:0034654 205 0.011
carboxylic acid metabolic process GO:0019752 22 0.011
regulation of nucleotide metabolic process GO:0006140 17 0.011
regulation of phosphate metabolic process GO:0019220 43 0.011
positive regulation of ras gtpase activity GO:0032320 1 0.011
proximal distal pattern formation GO:0009954 1 0.011
regulation of neurogenesis GO:0050767 87 0.011
regulation of transport GO:0051049 45 0.011
regulation of establishment of planar polarity GO:0090175 4 0.011
regulation of cell proliferation GO:0042127 37 0.011
cellular component movement GO:0006928 335 0.011
epithelial cell differentiation GO:0030855 116 0.011
transcription dna templated GO:0006351 181 0.011
rho protein signal transduction GO:0007266 5 0.011
intra s dna damage checkpoint GO:0031573 1 0.011
regulation of transmembrane transporter activity GO:0022898 2 0.011
synaptic vesicle endocytosis GO:0048488 1 0.011
cell death GO:0008219 121 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.011
regulation of metal ion transport GO:0010959 4 0.011
regulation of protein complex assembly GO:0043254 3 0.011
cellular response to xenobiotic stimulus GO:0071466 35 0.011
cellular response to organic substance GO:0071310 105 0.011
regulation of blood vessel size GO:0050880 2 0.011
pancreas development GO:0031016 84 0.011
lipid homeostasis GO:0055088 3 0.011
immune system process GO:0002376 241 0.011
proteasomal protein catabolic process GO:0010498 2 0.011
angiogenesis GO:0001525 158 0.011
protein localization to nucleus GO:0034504 3 0.010
nucleobase containing compound transport GO:0015931 2 0.010
positive regulation of cellular metabolic process GO:0031325 94 0.010
cation transport GO:0006812 81 0.010
axon development GO:0061564 166 0.010
auditory receptor cell fate commitment GO:0009912 4 0.010
protein dephosphorylation GO:0006470 3 0.010
lateral line system development GO:0048925 76 0.010
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.010
regulation of ion transmembrane transporter activity GO:0032412 2 0.010
phagocytosis GO:0006909 3 0.010
cellular respiration GO:0045333 3 0.010
synaptic target recognition GO:0008039 1 0.010
single organism intracellular transport GO:1902582 25 0.010
wnt signaling pathway GO:0016055 80 0.010
organic substance biosynthetic process GO:1901576 289 0.010
amine metabolic process GO:0009308 2 0.010

tube1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.042
nervous system disease DOID:863 0 0.019
retinal disease DOID:5679 0 0.015
retinal degeneration DOID:8466 0 0.015
sensory system disease DOID:0050155 0 0.015
eye and adnexa disease DOID:1492 0 0.015
eye disease DOID:5614 0 0.015
disease of cellular proliferation DOID:14566 0 0.011