Danio rerio

0 known processes

txndc5

thioredoxin domain containing 5

(Aliases: MGC66265,wu:fb20a07,wu:fb55b10,zgc:66265)

txndc5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.462
locomotion GO:0040011 313 0.229
cellular biosynthetic process GO:0044249 286 0.148
single organism metabolic process GO:0044710 217 0.144
establishment of localization GO:0051234 244 0.130
Fly
regulation of biological quality GO:0065008 263 0.125
positive regulation of protein complex assembly GO:0031334 2 0.118
positive regulation of cellular component biogenesis GO:0044089 3 0.113
regulation of reproductive process GO:2000241 4 0.108
regulation of protein complex assembly GO:0043254 3 0.104
maintenance of location GO:0051235 4 0.101
organelle organization GO:0006996 227 0.099
phagocytosis GO:0006909 3 0.095
Fly
protein n linked glycosylation GO:0006487 1 0.086
protein polymerization GO:0051258 4 0.080
meiotic nuclear division GO:0007126 4 0.078
neuron development GO:0048666 262 0.077
cell morphogenesis GO:0000902 289 0.074
regulation of protein polymerization GO:0032271 2 0.069
cell cycle GO:0007049 93 0.067
cell part morphogenesis GO:0032990 246 0.066
regulation of synapse assembly GO:0051963 3 0.065
synaptic growth at neuromuscular junction GO:0051124 2 0.064
cell projection organization GO:0030030 284 0.061
cytokinesis GO:0000910 3 0.061
macromolecule biosynthetic process GO:0009059 227 0.056
actin polymerization or depolymerization GO:0008154 2 0.056
cellular nitrogen compound metabolic process GO:0034641 290 0.054
regulation of synapse organization GO:0050807 3 0.054
actin filament polymerization GO:0030041 2 0.054
regulation of meiotic cell cycle GO:0051445 1 0.053
cell projection morphogenesis GO:0048858 244 0.053
organic substance biosynthetic process GO:1901576 289 0.053
cell substrate adhesion GO:0031589 4 0.053
gene expression GO:0010467 252 0.052
oocyte anterior posterior axis specification GO:0007314 4 0.052
regulation of multicellular organismal process GO:0051239 277 0.051
biosynthetic process GO:0009058 294 0.050
cellular macromolecule metabolic process GO:0044260 391 0.049
aging GO:0007568 2 0.048
digestive tract morphogenesis GO:0048546 231 0.048
ribonucleoside monophosphate catabolic process GO:0009158 4 0.046
lipid storage GO:0019915 1 0.046
single organism membrane fusion GO:0044801 2 0.046
nitrogen compound metabolic process GO:0006807 319 0.045
single organism organelle organization GO:1902589 199 0.045
generation of neurons GO:0048699 385 0.043
regulation of gene expression GO:0010468 265 0.043
embryo development ending in birth or egg hatching GO:0009792 271 0.043
multi organism process GO:0051704 134 0.043
ameboidal type cell migration GO:0001667 143 0.042
single organism localization GO:1902578 225 0.042
Fly
digestive tract development GO:0048565 265 0.041
regulation of multicellular organism growth GO:0040014 4 0.041
golgi vesicle transport GO:0048193 3 0.040
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.040
transcription dna templated GO:0006351 181 0.039
multicellular organism growth GO:0035264 4 0.038
digestive system development GO:0055123 289 0.038
heterocycle metabolic process GO:0046483 290 0.037
neuron differentiation GO:0030182 353 0.037
sensory organ development GO:0007423 393 0.037
heterocycle biosynthetic process GO:0018130 215 0.037
positive regulation of transport GO:0051050 2 0.036
Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.035
purine nucleoside monophosphate catabolic process GO:0009128 4 0.035
cell cycle process GO:0022402 53 0.035
response to chemical GO:0042221 320 0.034
carbohydrate derivative biosynthetic process GO:1901137 43 0.034
mitotic cell cycle GO:0000278 64 0.034
gastrulation GO:0007369 208 0.034
regulation of cellular biosynthetic process GO:0031326 245 0.033
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.033
cell division GO:0051301 20 0.033
organelle fusion GO:0048284 3 0.033
cellular macromolecule biosynthetic process GO:0034645 224 0.033
positive regulation of cellular process GO:0048522 201 0.032
negative regulation of biological process GO:0048519 304 0.032
regulation of anatomical structure size GO:0090066 33 0.032
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.032
positive regulation of developmental process GO:0051094 50 0.032
cellular component movement GO:0006928 335 0.031
lateral inhibition GO:0046331 1 0.031
positive regulation of biological process GO:0048518 253 0.031
Fly
regulation of cell division GO:0051302 12 0.030
cell death GO:0008219 121 0.030
positive regulation of cytoskeleton organization GO:0051495 3 0.029
signal transduction GO:0007165 455 0.029
protein localization to nucleus GO:0034504 3 0.029
regulation of cellular component organization GO:0051128 86 0.029
Fly
cellular component biogenesis GO:0044085 178 0.029
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.029
regulation of protein catabolic process GO:0042176 1 0.029
atp catabolic process GO:0006200 4 0.028
morphogenesis of an epithelium GO:0002009 333 0.028
cellular protein metabolic process GO:0044267 129 0.028
positive regulation of protein polymerization GO:0032273 2 0.028
death GO:0016265 121 0.028
adherens junction organization GO:0034332 4 0.027
regulation of primary metabolic process GO:0080090 311 0.027
rna biosynthetic process GO:0032774 181 0.027
developmental growth GO:0048589 166 0.027
growth GO:0040007 174 0.027
blood vessel development GO:0001568 246 0.027
aromatic compound biosynthetic process GO:0019438 217 0.027
amine metabolic process GO:0009308 2 0.026
cellular amine metabolic process GO:0044106 2 0.026
macromolecular complex disassembly GO:0032984 1 0.026
regulation of macromolecule metabolic process GO:0060255 317 0.026
cellular component disassembly GO:0022411 1 0.026
convergent extension GO:0060026 118 0.025
multicellular organismal reproductive process GO:0048609 35 0.025
localization of cell GO:0051674 244 0.025
cellular component morphogenesis GO:0032989 336 0.024
establishment of protein localization to organelle GO:0072594 4 0.024
organic cyclic compound metabolic process GO:1901360 301 0.024
regulation of biosynthetic process GO:0009889 250 0.024
nucleobase containing compound metabolic process GO:0006139 274 0.023
cellular nitrogen compound biosynthetic process GO:0044271 218 0.023
regulation of cell activation GO:0050865 1 0.023
organic cyclic compound biosynthetic process GO:1901362 223 0.023
regulation of multicellular organismal development GO:2000026 223 0.023
cell surface receptor signaling pathway GO:0007166 325 0.023
regulation of cell cycle GO:0051726 52 0.022
mononuclear cell proliferation GO:0032943 1 0.022
regulation of cellular metabolic process GO:0031323 320 0.022
regionalization GO:0003002 274 0.022
cytoskeleton dependent cytokinesis GO:0061640 3 0.022
protein import GO:0017038 3 0.022
protein metabolic process GO:0019538 183 0.022
germ line stem cell maintenance GO:0030718 2 0.022
regulation of organelle organization GO:0033043 29 0.022
protein complex disassembly GO:0043241 1 0.022
negative regulation of synapse assembly GO:0051964 2 0.021
membrane fusion GO:0061025 2 0.021
regulation of macromolecule biosynthetic process GO:0010556 225 0.021
regulation of chromosome segregation GO:0051983 1 0.021
negative regulation of protein phosphorylation GO:0001933 4 0.021
reproduction GO:0000003 40 0.021
axonogenesis GO:0007409 152 0.021
nucleocytoplasmic transport GO:0006913 4 0.021
negative regulation of protein kinase activity GO:0006469 4 0.020
organic acid metabolic process GO:0006082 31 0.020
meiotic cell cycle process GO:1903046 3 0.020
oxoacid metabolic process GO:0043436 31 0.020
regulation of developmental growth GO:0048638 38 0.020
neuron projection development GO:0031175 180 0.019
actin cytoskeleton organization GO:0030036 63 0.019
apoptotic process GO:0006915 116 0.019
cell motility GO:0048870 244 0.019
regulation of establishment of protein localization GO:0070201 4 0.019
cell morphogenesis involved in differentiation GO:0000904 195 0.019
regulation of developmental process GO:0050793 247 0.019
regulation of transcription dna templated GO:0006355 213 0.019
carboxylic acid metabolic process GO:0019752 22 0.019
cellular aromatic compound metabolic process GO:0006725 295 0.019
homeostatic process GO:0042592 142 0.019
positive regulation of multicellular organismal process GO:0051240 52 0.019
macromolecule modification GO:0043412 111 0.019
cytoskeleton organization GO:0007010 96 0.019
regulation of translational initiation GO:0006446 1 0.019
regulation of cellular amine metabolic process GO:0033238 0 0.018
pole plasm assembly GO:0007315 4 0.018
actin filament based process GO:0030029 64 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
cell migration involved in gastrulation GO:0042074 79 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
guanosine containing compound metabolic process GO:1901068 4 0.018
meiotic chromosome segregation GO:0045132 3 0.018
cellular protein modification process GO:0006464 100 0.018
cell migration GO:0016477 237 0.018
regulation of rna metabolic process GO:0051252 224 0.018
regulation of metal ion transport GO:0010959 4 0.018
mitochondrion organization GO:0007005 4 0.018
maternal determination of anterior posterior axis embryo GO:0008358 4 0.017
chordate embryonic development GO:0043009 271 0.017
translational initiation GO:0006413 3 0.017
regulation of dna replication GO:0006275 3 0.017
negative regulation of cellular process GO:0048523 283 0.017
protein homooligomerization GO:0051260 3 0.017
neuron projection morphogenesis GO:0048812 161 0.017
multicellular organism reproduction GO:0032504 35 0.017
cellular response to external stimulus GO:0071496 2 0.017
kidney development GO:0001822 92 0.017
positive regulation of secretion GO:0051047 1 0.017
blood vessel morphogenesis GO:0048514 216 0.017
regulation of oocyte development GO:0060281 3 0.017
macromolecular complex subunit organization GO:0043933 74 0.017
response to drug GO:0042493 3 0.017
cytoplasm organization GO:0007028 4 0.017
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.017
nuclear import GO:0051170 3 0.016
leukocyte proliferation GO:0070661 1 0.016
angiogenesis GO:0001525 158 0.016
cellular amino acid metabolic process GO:0006520 7 0.016
er to golgi vesicle mediated transport GO:0006888 1 0.016
reproductive process GO:0022414 40 0.016
transport GO:0006810 220 0.016
Fly
single organism nuclear import GO:1902593 3 0.016
negative regulation of reproductive process GO:2000242 3 0.016
regulation of protein localization to nucleus GO:1900180 2 0.016
adult behavior GO:0030534 2 0.016
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.016
regulation of binding GO:0051098 3 0.016
head development GO:0060322 303 0.016
regulation of filopodium assembly GO:0051489 2 0.016
nucleic acid metabolic process GO:0090304 244 0.016
cellular localization GO:0051641 97 0.016
response to external stimulus GO:0009605 264 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
axon development GO:0061564 166 0.016
glomerulus development GO:0032835 27 0.016
cellular component assembly GO:0022607 170 0.015
protein targeting to nucleus GO:0044744 3 0.015
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.015
response to biotic stimulus GO:0009607 97 0.015
autophagy GO:0006914 4 0.015
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.015
tube morphogenesis GO:0035239 349 0.015
membrane invagination GO:0010324 1 0.015
single organism biosynthetic process GO:0044711 71 0.015
negative regulation of metabolic process GO:0009892 86 0.015
mitochondrial transport GO:0006839 2 0.015
system process GO:0003008 185 0.015
cellular response to extracellular stimulus GO:0031668 2 0.015
regulation of stem cell differentiation GO:2000736 4 0.015
positive regulation of catabolic process GO:0009896 4 0.015
positive regulation of cell cycle GO:0045787 3 0.015
proteasomal protein catabolic process GO:0010498 2 0.014
regulation of microtubule cytoskeleton organization GO:0070507 3 0.014
positive regulation of chromatin modification GO:1903310 1 0.014
behavior GO:0007610 74 0.014
cellular component assembly involved in morphogenesis GO:0010927 107 0.014
single organism transport GO:0044765 206 0.014
Fly
regulation of cell projection assembly GO:0060491 4 0.014
renal system development GO:0072001 94 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
positive regulation of apoptotic signaling pathway GO:2001235 1 0.014
peptidyl serine modification GO:0018209 2 0.014
post golgi vesicle mediated transport GO:0006892 1 0.014
i kappab kinase nf kappab signaling GO:0007249 4 0.013
negative regulation of cellular metabolic process GO:0031324 77 0.013
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.013
rna metabolic process GO:0016070 219 0.013
negative regulation of kinase activity GO:0033673 4 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
regulation of nucleic acid templated transcription GO:1903506 213 0.013
positive regulation of cell division GO:0051781 2 0.013
nucleic acid templated transcription GO:0097659 181 0.013
regulation of cytoplasmic transport GO:1903649 4 0.013
negative regulation of chromosome organization GO:2001251 1 0.013
protein complex subunit organization GO:0071822 46 0.013
cellular transition metal ion homeostasis GO:0046916 3 0.013
nuclear transport GO:0051169 4 0.013
response to other organism GO:0051707 97 0.013
regulation of signal transduction GO:0009966 225 0.013
stem cell proliferation GO:0072089 4 0.013
endosomal transport GO:0016197 2 0.013
eye development GO:0001654 277 0.013
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.013
regulation of receptor mediated endocytosis GO:0048259 4 0.013
cellular component maintenance GO:0043954 3 0.012
response to stress GO:0006950 263 0.012
regulation of dendrite development GO:0050773 3 0.012
extrinsic apoptotic signaling pathway GO:0097191 3 0.012
spermatid development GO:0007286 2 0.012
osteoclast differentiation GO:0030316 1 0.012
establishment of localization in cell GO:0051649 77 0.012
hormone secretion GO:0046879 2 0.012
cellular protein complex assembly GO:0043623 19 0.012
organonitrogen compound metabolic process GO:1901564 74 0.012
regulation of protein complex disassembly GO:0043244 1 0.012
lymphocyte proliferation GO:0046651 1 0.012
positive regulation of cellular catabolic process GO:0031331 3 0.012
cellular ketone metabolic process GO:0042180 11 0.012
camera type eye development GO:0043010 222 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.012
negative chemotaxis GO:0050919 1 0.012
negative regulation of protein complex assembly GO:0031333 1 0.012
regulation of growth rate GO:0040009 1 0.012
central nervous system development GO:0007417 387 0.012
nucleobase containing compound biosynthetic process GO:0034654 205 0.012
female sex differentiation GO:0046660 4 0.012
determination of bilateral symmetry GO:0009855 204 0.012
protein modification process GO:0036211 100 0.012
regulation of locomotion GO:0040012 55 0.012
small molecule metabolic process GO:0044281 77 0.012
immune system process GO:0002376 241 0.012
alpha amino acid metabolic process GO:1901605 3 0.012
protein heterooligomerization GO:0051291 1 0.012
negative regulation of macromolecule metabolic process GO:0010605 76 0.012
striated muscle cell differentiation GO:0051146 129 0.012
gtp metabolic process GO:0046039 4 0.012
positive regulation of reproductive process GO:2000243 2 0.011
ovulation cycle GO:0042698 2 0.011
peptidyl serine phosphorylation GO:0018105 1 0.011
protein import into nucleus GO:0006606 3 0.011
cellular extravasation GO:0045123 1 0.011
cell proliferation GO:0008283 80 0.011
positive regulation of secretion by cell GO:1903532 1 0.011
gtp catabolic process GO:0006184 2 0.011
regulation of cellular component size GO:0032535 30 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
nucleoside monophosphate catabolic process GO:0009125 4 0.011
mitotic cytokinesis GO:0000281 3 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.011
regulation of protein binding GO:0043393 3 0.011
guanosine containing compound catabolic process GO:1901069 2 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.011
negative regulation of catabolic process GO:0009895 3 0.011
single organism reproductive process GO:0044702 40 0.011
modification dependent macromolecule catabolic process GO:0043632 3 0.011
actin filament organization GO:0007015 15 0.011
positive regulation of chromosome organization GO:2001252 1 0.011
stem cell maintenance GO:0019827 4 0.011
protein stabilization GO:0050821 2 0.011
female gonad development GO:0008585 4 0.011
regulation of localization GO:0032879 104 0.011
Fly
macromolecule glycosylation GO:0043413 9 0.011
g1 s transition of mitotic cell cycle GO:0000082 1 0.011
cellular modified amino acid metabolic process GO:0006575 3 0.011
microtubule based process GO:0007017 60 0.011
regulation of metabolic process GO:0019222 359 0.011
ubiquitin dependent protein catabolic process GO:0006511 3 0.010
protein depolymerization GO:0051261 1 0.010
neuroblast proliferation GO:0007405 2 0.010
segmentation GO:0035282 97 0.010
cell aging GO:0007569 2 0.010
muscle fiber development GO:0048747 52 0.010
muscle hypertrophy GO:0014896 2 0.010
embryonic heart tube development GO:0035050 133 0.010
regulation of protein transport GO:0051223 3 0.010
regulation of cell differentiation GO:0045595 142 0.010
phagocytosis engulfment GO:0006911 1 0.010
negative regulation of cytokine production GO:0001818 1 0.010
glycoprotein biosynthetic process GO:0009101 21 0.010
dorsal ventral pattern formation GO:0009953 125 0.010

txndc5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
bone disease DOID:0080001 0 0.010
musculoskeletal system disease DOID:17 0 0.010
connective tissue disease DOID:65 0 0.010