Danio rerio

0 known processes

u2af1

U2(RNU2) small nuclear RNA auxiliary factor 1

(Aliases: zgc:111896,CHUNP6860,MGC111896)

u2af1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.761
Worm
organic cyclic compound metabolic process GO:1901360 301 0.548
Fly
cellular macromolecule metabolic process GO:0044260 391 0.500
Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.488
Worm
nucleobase containing compound metabolic process GO:0006139 274 0.479
Fly
rna splicing GO:0008380 16 0.461
Fly
rna metabolic process GO:0016070 219 0.418
Fly
regulation of metabolic process GO:0019222 359 0.392
Fly
cell cycle GO:0007049 93 0.375
Fly
cellular aromatic compound metabolic process GO:0006725 295 0.374
Fly
heterocycle metabolic process GO:0046483 290 0.362
Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.349
Fly
nitrogen compound metabolic process GO:0006807 319 0.347
Fly
regulation of gene expression GO:0010468 265 0.303
Fly
gene expression GO:0010467 252 0.299
Fly
single organism organelle organization GO:1902589 199 0.292
Fly
regulation of biological quality GO:0065008 263 0.291
nucleic acid metabolic process GO:0090304 244 0.266
Fly
cell cycle process GO:0022402 53 0.260
Fly
neuron differentiation GO:0030182 353 0.239
mitotic cell cycle GO:0000278 64 0.230
Fly
response to stress GO:0006950 263 0.204
mrna splicing via spliceosome GO:0000398 10 0.199
Fly
regulation of mrna splicing via spliceosome GO:0048024 3 0.198
Fly
meiotic nuclear division GO:0007126 4 0.193
positive regulation of cell cycle GO:0045787 3 0.190
mrna metabolic process GO:0016071 20 0.183
Fly
reproduction GO:0000003 40 0.181
Worm
regulation of meiotic cell cycle GO:0051445 1 0.177
rna biosynthetic process GO:0032774 181 0.173
neuron development GO:0048666 262 0.157
organelle organization GO:0006996 227 0.139
Fly
heart development GO:0007507 313 0.132
aging GO:0007568 2 0.132
generation of neurons GO:0048699 385 0.132
macromolecular complex subunit organization GO:0043933 74 0.130
Fly
regulation of rna metabolic process GO:0051252 224 0.129
Fly
nucleobase containing compound biosynthetic process GO:0034654 205 0.129
nuclear transport GO:0051169 4 0.128
fertilization GO:0009566 3 0.116
regulation of multicellular organismal development GO:2000026 223 0.114
nuclear export GO:0051168 1 0.114
regulation of nitrogen compound metabolic process GO:0051171 251 0.107
Fly
microtubule cytoskeleton organization GO:0000226 33 0.106
Fly
single organism metabolic process GO:0044710 217 0.102
mrna processing GO:0006397 14 0.100
Fly
response to chemical GO:0042221 320 0.100
organelle assembly GO:0070925 110 0.098
regulation of nucleic acid templated transcription GO:1903506 213 0.096
negative regulation of cellular process GO:0048523 283 0.095
sensory organ development GO:0007423 393 0.093
spliceosomal snrnp assembly GO:0000387 2 0.091
sensory organ morphogenesis GO:0090596 200 0.090
rna splicing via transesterification reactions GO:0000375 10 0.089
Fly
regulation of cellular biosynthetic process GO:0031326 245 0.088
macromolecule biosynthetic process GO:0009059 227 0.088
organelle fission GO:0048285 23 0.086
transport GO:0006810 220 0.084
maintenance of location GO:0051235 4 0.084
cellular biosynthetic process GO:0044249 286 0.083
erk1 and erk2 cascade GO:0070371 4 0.083
cell projection organization GO:0030030 284 0.081
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.077
cellular component biogenesis GO:0044085 178 0.077
regulation of mrna processing GO:0050684 3 0.074
Fly
nucleocytoplasmic transport GO:0006913 4 0.071
rna processing GO:0006396 25 0.070
Fly
establishment of protein localization to organelle GO:0072594 4 0.069
cellular component assembly GO:0022607 170 0.068
transcription from rna polymerase ii promoter GO:0006366 80 0.068
signal transduction GO:0007165 455 0.068
regulation of developmental process GO:0050793 247 0.068
regulation of cellular metabolic process GO:0031323 320 0.066
Fly
cellular component morphogenesis GO:0032989 336 0.065
organic substance biosynthetic process GO:1901576 289 0.063
spindle organization GO:0007051 5 0.063
Fly
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 10 0.063
Fly
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.062
Fly
protein localization to nucleus GO:0034504 3 0.062
cytoskeleton organization GO:0007010 96 0.061
Fly
regulation of macromolecule metabolic process GO:0060255 317 0.061
Fly
regulation of cellular component organization GO:0051128 86 0.061
immune system development GO:0002520 191 0.060
regulation of macromolecule biosynthetic process GO:0010556 225 0.060
regulation of biosynthetic process GO:0009889 250 0.059
cell surface receptor signaling pathway GO:0007166 325 0.058
transcription dna templated GO:0006351 181 0.058
mitotic cell cycle process GO:1903047 48 0.058
Fly
death GO:0016265 121 0.057
developmental process involved in reproduction GO:0003006 27 0.057
Worm
mitotic nuclear division GO:0007067 18 0.057
regulation of signal transduction GO:0009966 225 0.056
cellular macromolecule biosynthetic process GO:0034645 224 0.055
neuron projection development GO:0031175 180 0.055
cellular nitrogen compound biosynthetic process GO:0044271 218 0.055
regulation of cell cycle GO:0051726 52 0.055
cell part morphogenesis GO:0032990 246 0.055
aromatic compound biosynthetic process GO:0019438 217 0.054
apoptotic process GO:0006915 116 0.053
establishment of localization GO:0051234 244 0.053
response to abiotic stimulus GO:0009628 122 0.053
negative regulation of biological process GO:0048519 304 0.051
phagocytosis GO:0006909 3 0.051
protein import GO:0017038 3 0.051
nuclear division GO:0000280 23 0.051
organic cyclic compound biosynthetic process GO:1901362 223 0.050
positive regulation of macromolecule metabolic process GO:0010604 93 0.050
eye development GO:0001654 277 0.050
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.050
reproductive process GO:0022414 40 0.050
Worm
eye morphogenesis GO:0048592 144 0.049
protein import into nucleus GO:0006606 3 0.048
proteasomal protein catabolic process GO:0010498 2 0.048
regulation of anatomical structure morphogenesis GO:0022603 130 0.048
single fertilization GO:0007338 3 0.048
nuclear import GO:0051170 3 0.048
cell projection morphogenesis GO:0048858 244 0.047
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.047
response to external stimulus GO:0009605 264 0.047
lipid storage GO:0019915 1 0.047
response to organic substance GO:0010033 153 0.044
ubiquitin dependent protein catabolic process GO:0006511 3 0.044
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.044
cell morphogenesis involved in differentiation GO:0000904 195 0.043
modification dependent protein catabolic process GO:0019941 3 0.043
cell death GO:0008219 121 0.042
oocyte anterior posterior axis specification GO:0007314 4 0.042
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.042
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.041
Fly
spermatid development GO:0007286 2 0.041
single organism nuclear import GO:1902593 3 0.041
regulation of multicellular organismal process GO:0051239 277 0.041
positive regulation of metabolic process GO:0009893 108 0.040
regulation of protein ubiquitination GO:0031396 3 0.040
regulation of rna biosynthetic process GO:2001141 213 0.039
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.039
protein targeting to nucleus GO:0044744 3 0.039
regulation of cell differentiation GO:0045595 142 0.038
alternative mrna splicing via spliceosome GO:0000380 1 0.036
Fly
germ cell development GO:0007281 22 0.036
mitotic g2 dna damage checkpoint GO:0007095 3 0.036
stem cell proliferation GO:0072089 4 0.036
cellular localization GO:0051641 97 0.035
spermatid differentiation GO:0048515 2 0.035
regulation of erk1 and erk2 cascade GO:0070372 4 0.034
locomotion GO:0040011 313 0.034
Worm
biosynthetic process GO:0009058 294 0.033
modification dependent macromolecule catabolic process GO:0043632 3 0.033
mitotic dna integrity checkpoint GO:0044774 4 0.033
macromolecular complex assembly GO:0065003 35 0.033
embryonic organ development GO:0048568 381 0.032
i kappab kinase nf kappab signaling GO:0007249 4 0.032
regionalization GO:0003002 274 0.032
cell morphogenesis GO:0000902 289 0.031
ras protein signal transduction GO:0007265 7 0.031
cellular protein metabolic process GO:0044267 129 0.031
digestive system development GO:0055123 289 0.030
regulation of transcription dna templated GO:0006355 213 0.030
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.030
pole plasm assembly GO:0007315 4 0.030
sexual reproduction GO:0019953 36 0.030
regulation of cell shape GO:0008360 1 0.029
positive regulation of cellular process GO:0048522 201 0.029
regulation of cell communication GO:0010646 232 0.029
cellular response to external stimulus GO:0071496 2 0.029
atp catabolic process GO:0006200 4 0.029
axonogenesis GO:0007409 152 0.028
cellular catabolic process GO:0044248 27 0.027
photoreceptor cell differentiation GO:0046530 55 0.027
cellular response to extracellular stimulus GO:0031668 2 0.027
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.027
negative regulation of rna splicing GO:0033119 1 0.026
negative regulation of metabolic process GO:0009892 86 0.026
nucleic acid templated transcription GO:0097659 181 0.026
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.026
spindle assembly GO:0051225 2 0.026
hemopoiesis GO:0030097 183 0.025
gamete generation GO:0007276 33 0.025
cellular response to stress GO:0033554 62 0.025
regulation of heart growth GO:0060420 2 0.025
response to temperature stimulus GO:0009266 15 0.025
cellular response to nutrient levels GO:0031669 2 0.025
ribonucleoside monophosphate catabolic process GO:0009158 4 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.024
regulation of signaling GO:0023051 235 0.024
neuron projection morphogenesis GO:0048812 161 0.024
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.024
meiotic cell cycle process GO:1903046 3 0.024
cell motility GO:0048870 244 0.024
autophagy GO:0006914 4 0.024
striated muscle cell differentiation GO:0051146 129 0.024
mitotic spindle organization GO:0007052 5 0.023
Fly
digestive tract development GO:0048565 265 0.023
organism emergence from protective structure GO:0071684 4 0.023
chemotaxis GO:0006935 104 0.023
anterior posterior pattern specification GO:0009952 152 0.023
multicellular organismal reproductive process GO:0048609 35 0.023
regulation of oocyte development GO:0060281 3 0.023
cognition GO:0050890 1 0.023
meiotic cell cycle GO:0051321 5 0.023
system process GO:0003008 185 0.023
myeloid cell differentiation GO:0030099 86 0.022
microtubule based process GO:0007017 60 0.022
Fly
meiotic chromosome segregation GO:0045132 3 0.022
single organism localization GO:1902578 225 0.022
cellular response to chemical stimulus GO:0070887 157 0.022
segmentation GO:0035282 97 0.022
positive regulation of biological process GO:0048518 253 0.022
cell proliferation GO:0008283 80 0.022
organic substance catabolic process GO:1901575 28 0.022
rna localization GO:0006403 4 0.022
maturation of ssu rrna GO:0030490 1 0.022
regulation of neurogenesis GO:0050767 87 0.021
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.021
developmental growth GO:0048589 166 0.021
spindle assembly involved in mitosis GO:0090307 1 0.021
positive regulation of cell communication GO:0010647 56 0.021
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 4 0.021
pronuclear migration GO:0035046 1 0.021
camera type eye development GO:0043010 222 0.021
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.021
localization of cell GO:0051674 244 0.021
dna templated transcription elongation GO:0006354 3 0.021
hatching GO:0035188 4 0.021
heterocycle biosynthetic process GO:0018130 215 0.021
negative regulation of cellular metabolic process GO:0031324 77 0.021
regulation of response to stimulus GO:0048583 269 0.021
protein complex assembly GO:0006461 30 0.020
regulation of reproductive process GO:2000241 4 0.020
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.020
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.020
cell substrate junction assembly GO:0007044 2 0.020
growth GO:0040007 174 0.020
single organism transport GO:0044765 206 0.020
regulation of cell development GO:0060284 100 0.020
tube morphogenesis GO:0035239 349 0.020
rna export from nucleus GO:0006405 1 0.020
organic acid metabolic process GO:0006082 31 0.020
nucleobase containing compound transport GO:0015931 2 0.020
mitotic dna damage checkpoint GO:0044773 4 0.019
axon development GO:0061564 166 0.019
regulation of cytoplasmic transport GO:1903649 4 0.019
positive regulation of cellular metabolic process GO:0031325 94 0.019
cellular component movement GO:0006928 335 0.019
neuroblast proliferation GO:0007405 2 0.019
central nervous system development GO:0007417 387 0.019
hematopoietic or lymphoid organ development GO:0048534 191 0.019
cellular protein catabolic process GO:0044257 4 0.019
regulation of epithelial cell proliferation GO:0050678 3 0.019
regulation of programmed cell death GO:0043067 101 0.019
carboxylic acid metabolic process GO:0019752 22 0.018
negative regulation of rna metabolic process GO:0051253 48 0.018
maternal determination of anterior posterior axis embryo GO:0008358 4 0.018
positive regulation of cell death GO:0010942 29 0.018
cellular response to biotic stimulus GO:0071216 3 0.018
actin filament based process GO:0030029 64 0.018
cytoplasm organization GO:0007028 4 0.018
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.017
regeneration GO:0031099 91 0.017
multicellular organism reproduction GO:0032504 35 0.017
multi organism process GO:0051704 134 0.017
cellular amine metabolic process GO:0044106 2 0.017
cellular response to starvation GO:0009267 1 0.017
proteolysis GO:0006508 38 0.017
phosphate containing compound metabolic process GO:0006796 108 0.017
chordate embryonic development GO:0043009 271 0.017
eye photoreceptor cell development GO:0042462 30 0.017
female gonad development GO:0008585 4 0.016
retina development in camera type eye GO:0060041 146 0.016
extrinsic apoptotic signaling pathway GO:0097191 3 0.016
regulation of rna splicing GO:0043484 8 0.016
Fly
muscle cell development GO:0055001 115 0.016
gtp catabolic process GO:0006184 2 0.016
negative regulation of developmental process GO:0051093 65 0.016
protein homooligomerization GO:0051260 3 0.016
small gtpase mediated signal transduction GO:0007264 8 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
positive regulation of cellular catabolic process GO:0031331 3 0.016
regulation of primary metabolic process GO:0080090 311 0.016
Fly
cell division GO:0051301 20 0.016
regulation of mitotic cell cycle GO:0007346 25 0.016
establishment of localization in cell GO:0051649 77 0.016
digestive tract morphogenesis GO:0048546 231 0.016
negative regulation of mrna processing GO:0050686 1 0.016
protein acetylation GO:0006473 2 0.016
regulation of nucleocytoplasmic transport GO:0046822 2 0.016
taxis GO:0042330 109 0.015
rna polyadenylation GO:0043631 2 0.015
protein complex disassembly GO:0043241 1 0.015
cell fate commitment GO:0045165 99 0.015
photoreceptor cell development GO:0042461 40 0.015
chemosensory behavior GO:0007635 1 0.015
g2 dna damage checkpoint GO:0031572 3 0.015
protein metabolic process GO:0019538 183 0.015
nucleoside monophosphate catabolic process GO:0009125 4 0.015
wnt signaling pathway GO:0016055 80 0.015
female sex differentiation GO:0046660 4 0.015
single organism reproductive process GO:0044702 40 0.015
Worm
positive regulation of nucleoside metabolic process GO:0045979 1 0.015
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.015
positive regulation of transport GO:0051050 2 0.015
regulation of stem cell proliferation GO:0072091 2 0.015
regulation of protein transport GO:0051223 3 0.015
negative regulation of myeloid cell differentiation GO:0045638 1 0.015
amine metabolic process GO:0009308 2 0.015
negative regulation of response to stimulus GO:0048585 104 0.014
ncrna catabolic process GO:0034661 1 0.014
organonitrogen compound metabolic process GO:1901564 74 0.014
rna 3 end processing GO:0031123 2 0.014
angiogenesis GO:0001525 158 0.014
regulation of cellular protein metabolic process GO:0032268 52 0.014
positive regulation of chromatin modification GO:1903310 1 0.014
regulation of protein metabolic process GO:0051246 56 0.014
response to radiation GO:0009314 51 0.014
homeostatic process GO:0042592 142 0.014
negative regulation of mrna metabolic process GO:1903312 3 0.014
cellular response to organic substance GO:0071310 105 0.014
protein polymerization GO:0051258 4 0.014
intracellular mrna localization GO:0008298 1 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
regulation of translational initiation GO:0006446 1 0.014
ear development GO:0043583 127 0.014
positive regulation of biosynthetic process GO:0009891 68 0.014
compound eye development GO:0048749 2 0.014
negative regulation of cell differentiation GO:0045596 46 0.014
protein complex biogenesis GO:0070271 30 0.013
macromolecular complex disassembly GO:0032984 1 0.013
positive regulation of catabolic process GO:0009896 4 0.013
enzyme linked receptor protein signaling pathway GO:0007167 106 0.013
muscle cell differentiation GO:0042692 139 0.013
purine nucleoside monophosphate catabolic process GO:0009128 4 0.013
peptidyl lysine acetylation GO:0018394 2 0.013
nucleic acid transport GO:0050657 2 0.013
positive regulation of dna templated transcription elongation GO:0032786 1 0.013
muscle organ development GO:0007517 101 0.013
establishment of rna localization GO:0051236 3 0.013
muscle structure development GO:0061061 196 0.013
regulation of rho protein signal transduction GO:0035023 2 0.013
regulation of cell cycle process GO:0010564 20 0.013
cell migration GO:0016477 237 0.013
negative regulation of transcription dna templated GO:0045892 45 0.013
cytoskeleton dependent cytokinesis GO:0061640 3 0.013
response to nutrient GO:0007584 3 0.013
embryonic pattern specification GO:0009880 44 0.013
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.013
regulation of cell maturation GO:1903429 1 0.013
protein secretion GO:0009306 1 0.012
neuron projection guidance GO:0097485 86 0.012
negative regulation of signal transduction GO:0009968 94 0.012
regulation of cell proliferation GO:0042127 37 0.012
regulation of organ growth GO:0046620 3 0.012
positive regulation of histone modification GO:0031058 1 0.012
cytokinesis GO:0000910 3 0.012
regulation of embryonic development GO:0045995 47 0.012
erythrocyte differentiation GO:0030218 54 0.012
regulation of cellular ketone metabolic process GO:0010565 7 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.012
gtp metabolic process GO:0046039 4 0.012
multicellular organism growth GO:0035264 4 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.012
forebrain regionalization GO:0021871 4 0.012
interspecies interaction between organisms GO:0044419 4 0.012
developmental maturation GO:0021700 34 0.012
membrane invagination GO:0010324 1 0.012
guanosine containing compound catabolic process GO:1901069 2 0.012
intracellular signal transduction GO:0035556 85 0.012
lateral inhibition GO:0046331 1 0.012
phosphorus metabolic process GO:0006793 109 0.012
cellular component disassembly GO:0022411 1 0.012
internal protein amino acid acetylation GO:0006475 2 0.012
primary neural tube formation GO:0014020 1 0.012
regulation of intracellular signal transduction GO:1902531 57 0.011
catabolic process GO:0009056 32 0.011
regulation of establishment of protein localization GO:0070201 4 0.011
intracellular transport GO:0046907 32 0.011
regulation of molecular function GO:0065009 70 0.011
development of primary female sexual characteristics GO:0046545 4 0.011
negative regulation of signaling GO:0023057 96 0.011
cell death in response to oxidative stress GO:0036473 2 0.011
negative regulation of neural precursor cell proliferation GO:2000178 1 0.011
stem cell division GO:0017145 1 0.011
multi organism reproductive process GO:0044703 36 0.011
striated muscle cell development GO:0055002 108 0.011
mrna 3 end processing GO:0031124 2 0.011
response to light stimulus GO:0009416 46 0.011
adult behavior GO:0030534 2 0.011
regulation of multicellular organism growth GO:0040014 4 0.011
gland development GO:0048732 143 0.011
axis specification GO:0009798 43 0.011
developmental cell growth GO:0048588 52 0.011
negative regulation of gene expression GO:0010629 65 0.010
regulation of dna templated transcription elongation GO:0032784 3 0.010
cell growth GO:0016049 57 0.010
programmed cell death GO:0012501 119 0.010
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.010
regulation of cell death GO:0010941 103 0.010
negative regulation of multicellular organismal process GO:0051241 69 0.010
guanosine containing compound metabolic process GO:1901068 4 0.010
regulation of protein catabolic process GO:0042176 1 0.010
regulation of protein import into nucleus GO:0042306 2 0.010
macromolecule localization GO:0033036 54 0.010
phagocytosis engulfment GO:0006911 1 0.010
regulation of protein localization to nucleus GO:1900180 2 0.010
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.010
sex determination GO:0007530 1 0.010
protein acylation GO:0043543 3 0.010

u2af1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org