Danio rerio

0 known processes

uba2

ubiquitin-like modifier activating enzyme 2

(Aliases: sae2b,sae2,uble1b,wu:fi17g06,zgc:66354)

uba2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.366
organic cyclic compound metabolic process GO:1901360 301 0.244
nucleic acid metabolic process GO:0090304 244 0.238
nucleobase containing compound metabolic process GO:0006139 274 0.201
response to stress GO:0006950 263 0.178
nucleic acid templated transcription GO:0097659 181 0.176
cellular nitrogen compound metabolic process GO:0034641 290 0.156
organelle organization GO:0006996 227 0.146
organic cyclic compound biosynthetic process GO:1901362 223 0.130
nitrogen compound metabolic process GO:0006807 319 0.127
negative regulation of biological process GO:0048519 304 0.126
regulation of signal transduction GO:0009966 225 0.122
regulation of nitrogen compound metabolic process GO:0051171 251 0.111
biosynthetic process GO:0009058 294 0.107
heterocycle biosynthetic process GO:0018130 215 0.104
cellular aromatic compound metabolic process GO:0006725 295 0.100
heterocycle metabolic process GO:0046483 290 0.096
central nervous system development GO:0007417 387 0.092
cellular macromolecule biosynthetic process GO:0034645 224 0.091
generation of neurons GO:0048699 385 0.086
rna biosynthetic process GO:0032774 181 0.085
positive regulation of cell cycle GO:0045787 3 0.084
protein acetylation GO:0006473 2 0.082
brain development GO:0007420 293 0.078
aromatic compound biosynthetic process GO:0019438 217 0.078
regulation of response to stimulus GO:0048583 269 0.078
negative regulation of response to stimulus GO:0048585 104 0.075
negative regulation of cellular process GO:0048523 283 0.074
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.072
rna metabolic process GO:0016070 219 0.071
single organism localization GO:1902578 225 0.070
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.068
maintenance of location GO:0051235 4 0.067
cellular macromolecule metabolic process GO:0044260 391 0.066
signal transduction GO:0007165 455 0.066
regulation of cell communication GO:0010646 232 0.066
negative regulation of signal transduction GO:0009968 94 0.066
tube morphogenesis GO:0035239 349 0.063
internal protein amino acid acetylation GO:0006475 2 0.061
cellular nitrogen compound biosynthetic process GO:0044271 218 0.060
cytokinesis GO:0000910 3 0.059
aging GO:0007568 2 0.059
digestive tract morphogenesis GO:0048546 231 0.058
negative regulation of cell communication GO:0010648 96 0.058
regulation of developmental process GO:0050793 247 0.057
regulation of rna metabolic process GO:0051252 224 0.057
negative regulation of signaling GO:0023057 96 0.056
digestive tract development GO:0048565 265 0.056
meiotic nuclear division GO:0007126 4 0.055
regulation of signaling GO:0023051 235 0.052
peptidyl lysine acetylation GO:0018394 2 0.049
embryonic organ development GO:0048568 381 0.048
response to wounding GO:0009611 116 0.048
nuclear transport GO:0051169 4 0.048
regionalization GO:0003002 274 0.048
microtubule organizing center organization GO:0031023 1 0.047
neuron development GO:0048666 262 0.046
nucleobase containing compound biosynthetic process GO:0034654 205 0.045
regulation of metabolic process GO:0019222 359 0.045
head development GO:0060322 303 0.044
cytoskeleton organization GO:0007010 96 0.043
regulation of rna biosynthetic process GO:2001141 213 0.043
protein acylation GO:0043543 3 0.042
chromosome organization GO:0051276 31 0.041
transport GO:0006810 220 0.041
gastrulation GO:0007369 208 0.039
regulation of macromolecule biosynthetic process GO:0010556 225 0.038
gene expression GO:0010467 252 0.038
internal peptidyl lysine acetylation GO:0018393 2 0.038
single organism metabolic process GO:0044710 217 0.038
cell substrate adhesion GO:0031589 4 0.038
response to drug GO:0042493 3 0.037
phagocytosis GO:0006909 3 0.037
regulation of meiotic cell cycle GO:0051445 1 0.036
cell migration GO:0016477 237 0.036
regulation of cell shape GO:0008360 1 0.036
regulation of cell cycle GO:0051726 52 0.035
transcription dna templated GO:0006351 181 0.035
nucleocytoplasmic transport GO:0006913 4 0.034
regulation of chromosome segregation GO:0051983 1 0.034
cellular ketone metabolic process GO:0042180 11 0.033
regulation of macromolecule metabolic process GO:0060255 317 0.033
meiotic chromosome segregation GO:0045132 3 0.033
regulation of biological quality GO:0065008 263 0.033
cellular carbohydrate metabolic process GO:0044262 4 0.033
neuron differentiation GO:0030182 353 0.033
regulation of cellular metabolic process GO:0031323 320 0.033
centrosome duplication GO:0051298 1 0.033
single organism organelle organization GO:1902589 199 0.032
positive regulation of biological process GO:0048518 253 0.032
centrosome organization GO:0051297 1 0.032
regulation of multicellular organismal process GO:0051239 277 0.031
small molecule metabolic process GO:0044281 77 0.031
protein metabolic process GO:0019538 183 0.030
protein localization to nucleus GO:0034504 3 0.030
wnt signaling pathway GO:0016055 80 0.030
multicellular organism growth GO:0035264 4 0.030
regulation of transcription dna templated GO:0006355 213 0.030
lipid storage GO:0019915 1 0.030
cell morphogenesis GO:0000902 289 0.029
mrna metabolic process GO:0016071 20 0.029
regulation of gene expression GO:0010468 265 0.029
determination of bilateral symmetry GO:0009855 204 0.029
cell part morphogenesis GO:0032990 246 0.029
locomotion GO:0040011 313 0.028
regulation of multicellular organismal development GO:2000026 223 0.028
meiotic cell cycle process GO:1903046 3 0.028
determination of left right symmetry GO:0007368 179 0.028
regeneration GO:0031099 91 0.027
response to glucose GO:0009749 3 0.027
response to external stimulus GO:0009605 264 0.026
regulation of protein transport GO:0051223 3 0.026
protein import into nucleus GO:0006606 3 0.026
positive regulation of cellular process GO:0048522 201 0.026
protein targeting to nucleus GO:0044744 3 0.026
specification of symmetry GO:0009799 204 0.025
mitotic cell cycle GO:0000278 64 0.025
cell cycle process GO:0022402 53 0.025
negative regulation of neuron projection regeneration GO:0070571 4 0.025
heart morphogenesis GO:0003007 156 0.024
developmental growth GO:0048589 166 0.024
stem cell maintenance GO:0019827 4 0.024
regulation of multicellular organism growth GO:0040014 4 0.024
positive regulation of cellular component biogenesis GO:0044089 3 0.024
cell projection organization GO:0030030 284 0.023
regulation of establishment of protein localization GO:0070201 4 0.023
cellular amino acid metabolic process GO:0006520 7 0.023
wound healing GO:0042060 90 0.023
regulation of intracellular protein transport GO:0033157 3 0.023
sensory organ development GO:0007423 393 0.023
digestive system development GO:0055123 289 0.023
positive regulation of transport GO:0051050 2 0.022
single organism nuclear import GO:1902593 3 0.022
macromolecule modification GO:0043412 111 0.022
regulation of protein localization to nucleus GO:1900180 2 0.022
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.021
negative regulation of biosynthetic process GO:0009890 55 0.021
rna localization GO:0006403 4 0.021
immune system process GO:0002376 241 0.021
regulation of cytoplasmic transport GO:1903649 4 0.021
regulation of cell differentiation GO:0045595 142 0.021
proteasomal protein catabolic process GO:0010498 2 0.021
apoptotic process GO:0006915 116 0.021
embryonic organ morphogenesis GO:0048562 274 0.021
response to chemical GO:0042221 320 0.021
organelle assembly GO:0070925 110 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
chromatin organization GO:0006325 22 0.020
heart development GO:0007507 313 0.020
g2 dna damage checkpoint GO:0031572 3 0.020
tissue regeneration GO:0042246 74 0.020
positive regulation of cellular biosynthetic process GO:0031328 68 0.020
response to monosaccharide GO:0034284 3 0.019
cell substrate junction assembly GO:0007044 2 0.019
establishment of localization GO:0051234 244 0.019
blood vessel development GO:0001568 246 0.019
cellular protein catabolic process GO:0044257 4 0.019
cell migration involved in gastrulation GO:0042074 79 0.019
regulation of cell development GO:0060284 100 0.019
mitotic g2 dna damage checkpoint GO:0007095 3 0.019
regulation of nervous system development GO:0051960 90 0.019
response to hexose GO:0009746 3 0.019
negative regulation of multicellular organismal process GO:0051241 69 0.019
regulation of carbohydrate metabolic process GO:0006109 4 0.019
cellular protein metabolic process GO:0044267 129 0.019
negative regulation of intracellular signal transduction GO:1902532 22 0.019
negative regulation of cellular biosynthetic process GO:0031327 55 0.018
nuclear migration GO:0007097 3 0.018
regulation of programmed cell death GO:0043067 101 0.018
negative regulation of macromolecule metabolic process GO:0010605 76 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.018
organic substance biosynthetic process GO:1901576 289 0.018
regulation of cellular ketone metabolic process GO:0010565 7 0.018
regulation of stem cell proliferation GO:0072091 2 0.018
regulation of protein import into nucleus GO:0042306 2 0.018
regulation of cellular amine metabolic process GO:0033238 0 0.018
centrosome cycle GO:0007098 1 0.018
cellular component movement GO:0006928 335 0.017
angiogenesis GO:0001525 158 0.017
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.017
regulation of nucleic acid templated transcription GO:1903506 213 0.017
regulation of cellular biosynthetic process GO:0031326 245 0.017
negative regulation of developmental process GO:0051093 65 0.017
cell aging GO:0007569 2 0.017
regulation of stem cell differentiation GO:2000736 4 0.017
regulation of biosynthetic process GO:0009889 250 0.017
g1 s transition of mitotic cell cycle GO:0000082 1 0.017
segmentation GO:0035282 97 0.016
cell projection morphogenesis GO:0048858 244 0.016
muscle structure development GO:0061061 196 0.016
regulation of wnt signaling pathway GO:0030111 53 0.016
homeostatic process GO:0042592 142 0.016
camera type eye development GO:0043010 222 0.016
non recombinational repair GO:0000726 2 0.016
cellular component disassembly GO:0022411 1 0.016
localization of cell GO:0051674 244 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.016
peptidyl serine modification GO:0018209 2 0.016
positive regulation of rna metabolic process GO:0051254 59 0.016
g2 m transition of mitotic cell cycle GO:0000086 4 0.016
protein modification process GO:0036211 100 0.016
intracellular signal transduction GO:0035556 85 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
eye development GO:0001654 277 0.016
protein secretion GO:0009306 1 0.016
regulation of cell death GO:0010941 103 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.016
cytoskeleton dependent cytokinesis GO:0061640 3 0.015
chordate embryonic development GO:0043009 271 0.015
cellular amine metabolic process GO:0044106 2 0.015
embryo development ending in birth or egg hatching GO:0009792 271 0.015
cellular response to chemical stimulus GO:0070887 157 0.015
macromolecule localization GO:0033036 54 0.015
protein import GO:0017038 3 0.015
embryonic digestive tract development GO:0048566 4 0.015
protein complex localization GO:0031503 1 0.015
neuron projection development GO:0031175 180 0.015
protein methylation GO:0006479 13 0.015
growth GO:0040007 174 0.015
cellular biosynthetic process GO:0044249 286 0.015
establishment of protein localization to organelle GO:0072594 4 0.015
guanosine containing compound metabolic process GO:1901068 4 0.015
regulation of protein complex assembly GO:0043254 3 0.015
regulation of synapse organization GO:0050807 3 0.015
mitotic cell cycle process GO:1903047 48 0.015
mitotic dna integrity checkpoint GO:0044774 4 0.015
chromatin modification GO:0016568 21 0.015
fin regeneration GO:0031101 51 0.015
modification dependent protein catabolic process GO:0019941 3 0.014
negative regulation of cellular metabolic process GO:0031324 77 0.014
macromolecular complex subunit organization GO:0043933 74 0.014
cell matrix adhesion GO:0007160 4 0.014
anterior posterior pattern specification GO:0009952 152 0.014
regulation of protein targeting GO:1903533 2 0.014
regulation of carbohydrate biosynthetic process GO:0043255 1 0.014
eye morphogenesis GO:0048592 144 0.014
regulation of dna recombination GO:0000018 2 0.013
system process GO:0003008 185 0.013
regulation of cell activation GO:0050865 1 0.013
cell cycle g2 m phase transition GO:0044839 4 0.013
cell morphogenesis involved in differentiation GO:0000904 195 0.013
regulation of circadian rhythm GO:0042752 4 0.013
mrna 3 end processing GO:0031124 2 0.013
positive regulation of dna metabolic process GO:0051054 1 0.013
multi organism process GO:0051704 134 0.013
protein polyubiquitination GO:0000209 4 0.013
amine metabolic process GO:0009308 2 0.013
cellular protein modification process GO:0006464 100 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
muscle organ development GO:0007517 101 0.013
cell motility GO:0048870 244 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.012
organonitrogen compound metabolic process GO:1901564 74 0.012
transcription from rna polymerase ii promoter GO:0006366 80 0.012
cell death GO:0008219 121 0.012
glucose homeostasis GO:0042593 1 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
positive regulation of transcription dna templated GO:0045893 57 0.012
organic acid metabolic process GO:0006082 31 0.012
regulation of synapse assembly GO:0051963 3 0.012
cellular localization GO:0051641 97 0.012
negative regulation of metabolic process GO:0009892 86 0.012
mitotic dna damage checkpoint GO:0044773 4 0.012
chromosome segregation GO:0007059 12 0.012
response to biotic stimulus GO:0009607 97 0.012
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.012
negative regulation of apoptotic process GO:0043066 55 0.012
ubiquitin dependent protein catabolic process GO:0006511 3 0.012
regulation of mitotic cell cycle GO:0007346 25 0.012
macromolecule biosynthetic process GO:0009059 227 0.012
cell cycle GO:0007049 93 0.012
regulation of apoptotic process GO:0042981 98 0.012
negative regulation of nucleic acid templated transcription GO:1903507 45 0.012
regulation of anatomical structure morphogenesis GO:0022603 130 0.011
cell fate commitment GO:0045165 99 0.011
positive regulation of macromolecule metabolic process GO:0010604 93 0.011
regulation of neurogenesis GO:0050767 87 0.011
energy reserve metabolic process GO:0006112 2 0.011
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.011
protein complex disassembly GO:0043241 1 0.011
regulation of mitotic cell cycle phase transition GO:1901990 8 0.011
autophagy GO:0006914 4 0.011
oocyte anterior posterior axis specification GO:0007314 4 0.011
embryonic digestive tract morphogenesis GO:0048557 3 0.011
sensory organ morphogenesis GO:0090596 200 0.011
response to carbohydrate GO:0009743 3 0.011
negative regulation of transcription dna templated GO:0045892 45 0.011
blood vessel morphogenesis GO:0048514 216 0.011
microtubule based process GO:0007017 60 0.011
pharyngeal muscle development GO:0043282 4 0.011
embryonic heart tube morphogenesis GO:0003143 108 0.011
programmed cell death GO:0012501 119 0.011
signal transduction by p53 class mediator GO:0072331 13 0.011
fertilization GO:0009566 3 0.011
meiosis i GO:0007127 1 0.011
regulation of canonical wnt signaling pathway GO:0060828 34 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
negative regulation of gene expression GO:0010629 65 0.011
carboxylic acid metabolic process GO:0019752 22 0.011
cellular component morphogenesis GO:0032989 336 0.011
cellular response to stress GO:0033554 62 0.011
regulation of microtubule cytoskeleton organization GO:0070507 3 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
positive regulation of carbohydrate metabolic process GO:0045913 1 0.011
cell fate specification GO:0001708 68 0.011
regulation of protein catabolic process GO:0042176 1 0.011
synaptic growth at neuromuscular junction GO:0051124 2 0.011
response to organic substance GO:0010033 153 0.010
protein localization to plasma membrane GO:0072659 1 0.010
locomotor rhythm GO:0045475 3 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.010
mitotic g2 m transition checkpoint GO:0044818 3 0.010
male meiosis GO:0007140 2 0.010
immunoglobulin mediated immune response GO:0016064 3 0.010
single organism biosynthetic process GO:0044711 71 0.010
nuclear import GO:0051170 3 0.010
sequestering of calcium ion GO:0051208 3 0.010
dorsal ventral pattern formation GO:0009953 125 0.010
embryonic heart tube development GO:0035050 133 0.010
establishment of localization in cell GO:0051649 77 0.010
positive regulation of apoptotic signaling pathway GO:2001235 1 0.010
negative regulation of catabolic process GO:0009895 3 0.010
stem cell differentiation GO:0048863 117 0.010

uba2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014
disease of metabolism DOID:0014667 0 0.011