Danio rerio

0 known processes

ube2i2

ubiquitin-conjugating enzyme E2I2

(Aliases: Ubc9-2,ube2ib)

ube2i2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular macromolecule metabolic process GO:0044260 391 0.560
Human Yeast Zebrafish Mouse Rat Worm Fly
cellular macromolecule biosynthetic process GO:0034645 224 0.530
Human Mouse Rat Worm
macromolecule biosynthetic process GO:0009059 227 0.501
Human Mouse Rat Worm
gene expression GO:0010467 252 0.482
Human Mouse Rat Worm
regulation of metabolic process GO:0019222 359 0.430
Human Mouse Rat Worm
regulation of nitrogen compound metabolic process GO:0051171 251 0.376
Human Mouse Rat Worm
mitotic g2 dna damage checkpoint GO:0007095 3 0.354
Fly
biosynthetic process GO:0009058 294 0.343
Human Mouse Rat Worm
regulation of macromolecule metabolic process GO:0060255 317 0.314
Human Mouse Rat Worm
regulation of macromolecule biosynthetic process GO:0010556 225 0.304
Human Mouse Rat Worm
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.294
Human Mouse Rat Worm
larval development GO:0002164 2 0.292
Worm Fly
regulation of cellular metabolic process GO:0031323 320 0.284
Human Mouse Rat Worm
organic substance biosynthetic process GO:1901576 289 0.278
Human Mouse Rat Worm
regulation of biosynthetic process GO:0009889 250 0.241
Human Mouse Rat Worm
cellular ketone metabolic process GO:0042180 11 0.227
positive regulation of cell cycle GO:0045787 3 0.210
chromosome organization GO:0051276 31 0.201
transcription from rna polymerase ii promoter GO:0006366 80 0.199
Human Mouse Worm
heterocycle biosynthetic process GO:0018130 215 0.183
Human Mouse Rat Worm
regulation of cellular amine metabolic process GO:0033238 0 0.177
regulation of mrna processing GO:0050684 3 0.174
positive regulation of cellular process GO:0048522 201 0.171
Mouse Rat
positive regulation of biological process GO:0048518 253 0.169
Mouse Rat
cellular aromatic compound metabolic process GO:0006725 295 0.167
Human Mouse Rat Worm
regulation of primary metabolic process GO:0080090 311 0.163
Human Mouse Rat Worm
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.159
Rat
nucleic acid metabolic process GO:0090304 244 0.159
Human Mouse Rat Worm
nucleobase containing compound metabolic process GO:0006139 274 0.158
Human Mouse Rat Worm
cell surface receptor signaling pathway GO:0007166 325 0.156
Fly
mitotic dna integrity checkpoint GO:0044774 4 0.156
Fly
positive regulation of cellular component biogenesis GO:0044089 3 0.155
regulation of cellular amino acid metabolic process GO:0006521 0 0.151
cellular nitrogen compound biosynthetic process GO:0044271 218 0.151
Human Mouse Rat Worm
protein localization to nucleus GO:0034504 3 0.151
Fly
regulation of cellular ketone metabolic process GO:0010565 7 0.137
amine metabolic process GO:0009308 2 0.133
cellular protein metabolic process GO:0044267 129 0.131
Human Yeast Zebrafish Rat Worm Fly
organic cyclic compound metabolic process GO:1901360 301 0.129
Human Mouse Rat Worm
nucleobase containing compound biosynthetic process GO:0034654 205 0.126
Human Mouse Rat Worm
organic cyclic compound biosynthetic process GO:1901362 223 0.123
Human Mouse Rat Worm
organelle organization GO:0006996 227 0.122
Yeast Zebrafish Fly
regulation of transcription dna templated GO:0006355 213 0.121
Human Mouse Rat Worm
cellular protein catabolic process GO:0044257 4 0.121
Rat
regulation of rna metabolic process GO:0051252 224 0.113
Human Mouse Rat Worm
regulation of nucleic acid templated transcription GO:1903506 213 0.112
Human Mouse Rat Worm
nuclear migration GO:0007097 3 0.112
heterocycle metabolic process GO:0046483 290 0.110
Human Mouse Rat Worm
cellular protein modification process GO:0006464 100 0.106
Human Yeast Zebrafish Rat Worm Fly
regulation of protein binding GO:0043393 3 0.105
neuroblast proliferation GO:0007405 2 0.105
negative regulation of protein kinase activity GO:0006469 4 0.105
rna biosynthetic process GO:0032774 181 0.101
Human Mouse Rat Worm
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.097
Human Mouse Rat Worm
nitrogen compound metabolic process GO:0006807 319 0.097
Human Mouse Rat Worm
aromatic compound biosynthetic process GO:0019438 217 0.097
Human Mouse Rat Worm
regulation of protein polymerization GO:0032271 2 0.093
regulation of protein localization to nucleus GO:1900180 2 0.091
oxoacid metabolic process GO:0043436 31 0.090
regulation of cellular biosynthetic process GO:0031326 245 0.089
Human Mouse Rat Worm
negative regulation of kinase activity GO:0033673 4 0.088
negative regulation of cellular process GO:0048523 283 0.087
Human Mouse Worm Fly
peptidyl lysine acetylation GO:0018394 2 0.085
cellular biosynthetic process GO:0044249 286 0.084
Human Mouse Rat Worm
regulation of cellular protein metabolic process GO:0032268 52 0.084
pronuclear migration GO:0035046 1 0.083
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.083
protein dephosphorylation GO:0006470 3 0.083
regulation of gene expression GO:0010468 265 0.082
Human Mouse Rat Worm
cell death GO:0008219 121 0.082
Worm
aging GO:0007568 2 0.081
internal protein amino acid acetylation GO:0006475 2 0.080
embryo development ending in birth or egg hatching GO:0009792 271 0.078
Worm Fly
modification dependent macromolecule catabolic process GO:0043632 3 0.078
Rat
regulation of mrna splicing via spliceosome GO:0048024 3 0.077
carboxylic acid metabolic process GO:0019752 22 0.076
rna metabolic process GO:0016070 219 0.076
Human Mouse Rat Worm
cellular component disassembly GO:0022411 1 0.075
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.075
negative regulation of gene expression GO:0010629 65 0.073
Human Mouse Worm
positive regulation of translation GO:0045727 1 0.072
actin filament polymerization GO:0030041 2 0.071
negative regulation of protein phosphorylation GO:0001933 4 0.071
cellular amino acid metabolic process GO:0006520 7 0.070
response to stress GO:0006950 263 0.069
Worm Fly
actin polymerization or depolymerization GO:0008154 2 0.068
positive regulation of metabolic process GO:0009893 108 0.067
nucleic acid templated transcription GO:0097659 181 0.067
Human Mouse Rat Worm
protein acetylation GO:0006473 2 0.067
multicellular organism growth GO:0035264 4 0.067
positive regulation of biosynthetic process GO:0009891 68 0.067
ubiquitin dependent protein catabolic process GO:0006511 3 0.066
Rat
chromosome segregation GO:0007059 12 0.066
Fly
alternative mrna splicing via spliceosome GO:0000380 1 0.066
negative regulation of metabolic process GO:0009892 86 0.065
Human Mouse Worm
regulation of meiotic cell cycle GO:0051445 1 0.065
erk1 and erk2 cascade GO:0070371 4 0.065
protein metabolic process GO:0019538 183 0.065
Human Yeast Zebrafish Rat Worm Fly
generation of neurons GO:0048699 385 0.064
stem cell proliferation GO:0072089 4 0.064
regulation of cell communication GO:0010646 232 0.064
Mouse Rat Fly
protein stabilization GO:0050821 2 0.064
protein targeting to nucleus GO:0044744 3 0.063
Fly
neuron differentiation GO:0030182 353 0.063
single organism organelle organization GO:1902589 199 0.062
Yeast Zebrafish
centrosome duplication GO:0051298 1 0.060
negative regulation of biological process GO:0048519 304 0.060
Human Mouse Worm Fly
nucleocytoplasmic transport GO:0006913 4 0.059
Fly
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.058
positive regulation of transcription dna templated GO:0045893 57 0.057
negative regulation of neural precursor cell proliferation GO:2000178 1 0.057
negative regulation of ras protein signal transduction GO:0046580 1 0.057
nuclear transport GO:0051169 4 0.056
Fly
protein modification process GO:0036211 100 0.056
Human Yeast Zebrafish Rat Worm Fly
organic acid metabolic process GO:0006082 31 0.056
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.055
Rat
internal peptidyl lysine acetylation GO:0018393 2 0.055
muscle structure development GO:0061061 196 0.055
Worm
single organism metabolic process GO:0044710 217 0.055
transcription dna templated GO:0006351 181 0.054
Human Mouse Rat Worm
cytoskeleton organization GO:0007010 96 0.054
Yeast
positive regulation of cellular amine metabolic process GO:0033240 0 0.052
regulation of binding GO:0051098 3 0.052
positive regulation of gene expression GO:0010628 71 0.052
regulation of protein complex assembly GO:0043254 3 0.052
protein import into nucleus GO:0006606 3 0.051
Fly
blood circulation GO:0008015 87 0.051
protein acylation GO:0043543 3 0.051
negative regulation of protein complex assembly GO:0031333 1 0.051
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.049
cellular amine metabolic process GO:0044106 2 0.049
neuromuscular synaptic transmission GO:0007274 2 0.049
positive regulation of rna biosynthetic process GO:1902680 57 0.049
positive regulation of cellular metabolic process GO:0031325 94 0.048
blood vessel morphogenesis GO:0048514 216 0.048
regulation of establishment of protein localization GO:0070201 4 0.047
protein complex disassembly GO:0043241 1 0.047
chromatin organization GO:0006325 22 0.047
autophagy GO:0006914 4 0.047
nuclear import GO:0051170 3 0.047
Fly
mitotic cell cycle GO:0000278 64 0.046
Yeast Zebrafish Fly
macromolecule modification GO:0043412 111 0.046
Human Yeast Zebrafish Rat Worm Fly
regulation of protein metabolic process GO:0051246 56 0.046
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.046
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.046
maintenance of location GO:0051235 4 0.045
regulation of mitotic cell cycle GO:0007346 25 0.045
Zebrafish Fly
mitotic dna damage checkpoint GO:0044773 4 0.045
Fly
modification dependent protein catabolic process GO:0019941 3 0.044
Rat
single organism nuclear import GO:1902593 3 0.044
Fly
positive regulation of catabolic process GO:0009896 4 0.044
mitotic g2 m transition checkpoint GO:0044818 3 0.044
Fly
negative regulation of mitotic cell cycle phase transition GO:1901991 5 0.043
Fly
lamellipodium assembly GO:0030032 1 0.042
cell substrate adhesion GO:0031589 4 0.042
stem cell division GO:0017145 1 0.042
peptidyl serine phosphorylation GO:0018105 1 0.042
cellular nitrogen compound metabolic process GO:0034641 290 0.042
Human Mouse Rat Worm
positive regulation of transport GO:0051050 2 0.042
positive regulation of macromolecule metabolic process GO:0010604 93 0.041
wnt signaling pathway GO:0016055 80 0.041
vasculature development GO:0001944 278 0.040
cell cycle g2 m phase transition GO:0044839 4 0.040
rna splicing GO:0008380 16 0.040
spermatid differentiation GO:0048515 2 0.040
fertilization GO:0009566 3 0.039
phagocytosis GO:0006909 3 0.039
mitotic cell cycle embryonic GO:0045448 2 0.038
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.038
regulation of cell substrate adhesion GO:0010810 1 0.038
signal transduction GO:0007165 455 0.038
Mouse Rat Fly
regulation of protein transport GO:0051223 3 0.038
translational initiation GO:0006413 3 0.037
cellular component morphogenesis GO:0032989 336 0.037
negative regulation of cellular metabolic process GO:0031324 77 0.037
Human Mouse Worm
multi organism process GO:0051704 134 0.035
Worm Fly
positive regulation of cell division GO:0051781 2 0.035
protein complex localization GO:0031503 1 0.035
positive regulation of dna metabolic process GO:0051054 1 0.035
regulation of cell projection assembly GO:0060491 4 0.035
system process GO:0003008 185 0.034
neutrophil mediated immunity GO:0002446 1 0.034
regulation of intracellular protein transport GO:0033157 3 0.034
single fertilization GO:0007338 3 0.034
membrane invagination GO:0010324 1 0.034
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.034
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.033
regulation of protein catabolic process GO:0042176 1 0.033
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.033
regulation of rna biosynthetic process GO:2001141 213 0.033
Human Mouse Rat Worm
negative regulation of chromosome organization GO:2001251 1 0.033
cytoskeleton dependent cytokinesis GO:0061640 3 0.033
proteasomal protein catabolic process GO:0010498 2 0.033
Rat
regulation of cell shape GO:0008360 1 0.033
covalent chromatin modification GO:0016569 20 0.033
regulation of cell cycle GO:0051726 52 0.033
Zebrafish Fly
cell cycle process GO:0022402 53 0.033
Yeast Zebrafish Fly
protein polymerization GO:0051258 4 0.033
central nervous system development GO:0007417 387 0.032
mechanosensory behavior GO:0007638 2 0.032
negative regulation of catalytic activity GO:0043086 21 0.032
er to golgi vesicle mediated transport GO:0006888 1 0.032
establishment of nucleus localization GO:0040023 7 0.032
regulation of cellular protein catabolic process GO:1903362 1 0.032
cellular component assembly GO:0022607 170 0.031
digestive system development GO:0055123 289 0.031
Worm
establishment of localization GO:0051234 244 0.031
Fly
regulation of protein ubiquitination GO:0031396 3 0.031
regulation of translational initiation GO:0006446 1 0.031
carbohydrate derivative biosynthetic process GO:1901137 43 0.031
cellular carbohydrate metabolic process GO:0044262 4 0.031
positive regulation of cellular extravasation GO:0002693 1 0.030
regulation of neurogenesis GO:0050767 87 0.030
cytokinesis GO:0000910 3 0.030
spliceosomal complex assembly GO:0000245 1 0.030
localization of cell GO:0051674 244 0.029
Fly
regulation of organelle organization GO:0033043 29 0.029
Zebrafish
specification of axis polarity GO:0065001 4 0.029
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.029
regulation of synapse assembly GO:0051963 3 0.029
regulation of stem cell differentiation GO:2000736 4 0.028
positive regulation of stress activated mapk cascade GO:0032874 3 0.028
sensory perception of touch GO:0050975 2 0.028
cellular extravasation GO:0045123 1 0.028
intracellular signal transduction GO:0035556 85 0.028
Mouse
spermatid development GO:0007286 2 0.028
muscle organ development GO:0007517 101 0.028
Worm
response to abiotic stimulus GO:0009628 122 0.028
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 4 0.028
regulation of calcium dependent cell cell adhesion GO:0046586 1 0.027
cognition GO:0050890 1 0.027
dna templated transcription elongation GO:0006354 3 0.027
regulation of cellular extravasation GO:0002691 1 0.027
positive regulation of myeloid cell differentiation GO:0045639 2 0.027
positive regulation of cellular biosynthetic process GO:0031328 68 0.027
locomotion GO:0040011 313 0.027
Worm Fly
regulation of dna templated transcription elongation GO:0032784 3 0.027
immune system process GO:0002376 241 0.026
Fly
membrane repolarization GO:0086009 2 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.026
pole plasm assembly GO:0007315 4 0.026
regulation of biological quality GO:0065008 263 0.026
Zebrafish
establishment of protein localization to organelle GO:0072594 4 0.026
Fly
positive regulation of rna metabolic process GO:0051254 59 0.026
peptidyl serine modification GO:0018209 2 0.026
protein import GO:0017038 3 0.026
Fly
regulation of signaling GO:0023051 235 0.025
Mouse Rat Fly
cell motility GO:0048870 244 0.025
Fly
positive regulation of protein complex assembly GO:0031334 2 0.025
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.025
muscle cell differentiation GO:0042692 139 0.025
apoptotic process GO:0006915 116 0.025
Worm
golgi vesicle transport GO:0048193 3 0.025
regulation of oocyte development GO:0060281 3 0.025
centrosome organization GO:0051297 1 0.025
single organism membrane fusion GO:0044801 2 0.024
regulation of tube size GO:0035150 2 0.024
transport GO:0006810 220 0.024
Fly
g2 dna damage checkpoint GO:0031572 3 0.024
Fly
heart development GO:0007507 313 0.024
peptide transport GO:0015833 1 0.024
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.024
Human Mouse Worm
neuron projection morphogenesis GO:0048812 161 0.024
regulation of nucleocytoplasmic transport GO:0046822 2 0.024
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.024
organonitrogen compound metabolic process GO:1901564 74 0.023
adherens junction organization GO:0034332 4 0.023
regulation of neutrophil extravasation GO:2000389 1 0.023
purine nucleoside monophosphate catabolic process GO:0009128 4 0.023
small gtpase mediated signal transduction GO:0007264 8 0.023
regulation of stem cell proliferation GO:0072091 2 0.023
protein modification by small protein removal GO:0070646 1 0.023
protein localization GO:0008104 40 0.023
Worm Fly
microtubule based process GO:0007017 60 0.022
Yeast
regulation of signal transduction GO:0009966 225 0.022
Mouse Rat Fly
microtubule organizing center organization GO:0031023 1 0.022
positive regulation of neutrophil migration GO:1902624 0 0.022
nuclear export GO:0051168 1 0.022
negative regulation of calcium dependent cell cell adhesion GO:0046588 1 0.022
membrane fusion GO:0061025 2 0.022
response to chemical GO:0042221 320 0.022
Fly
macromolecular complex disassembly GO:0032984 1 0.021
regulation of microtubule cytoskeleton organization GO:0070507 3 0.021
cellular component biogenesis GO:0044085 178 0.021
regulation of cellular component organization GO:0051128 86 0.021
Zebrafish
positive regulation of dna templated transcription elongation GO:0032786 1 0.021
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.021
dorsal ventral pattern formation GO:0009953 125 0.021
Fly
regulation of cytokine production GO:0001817 3 0.021
digestive tract development GO:0048565 265 0.021
Worm
negative regulation of cellular protein metabolic process GO:0032269 16 0.021
regulation of multicellular organism growth GO:0040014 4 0.021
positive regulation of ras protein signal transduction GO:0046579 1 0.021
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.020
regulation of cytoskeleton organization GO:0051493 11 0.020
cellular localization GO:0051641 97 0.020
Fly
regulation of cell cycle phase transition GO:1901987 8 0.020
Fly
phagocytosis engulfment GO:0006911 1 0.020
regulation of cell death GO:0010941 103 0.020
positive regulation of jnk cascade GO:0046330 3 0.020
regulation of nucleoside metabolic process GO:0009118 2 0.020
regulation of receptor activity GO:0010469 2 0.020
Rat
blood vessel development GO:0001568 246 0.019
mrna metabolic process GO:0016071 20 0.019
positive regulation of nucleoside metabolic process GO:0045979 1 0.019
meiotic cell cycle process GO:1903046 3 0.019
Fly
cytoplasm organization GO:0007028 4 0.019
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.019
meiotic chromosome segregation GO:0045132 3 0.019
Fly
neuron development GO:0048666 262 0.019
keratinocyte differentiation GO:0030216 0 0.019
g1 s transition of mitotic cell cycle GO:0000082 1 0.019
positive regulation of cellular catabolic process GO:0031331 3 0.019
small molecule metabolic process GO:0044281 77 0.019
cell part morphogenesis GO:0032990 246 0.019
regulation of phosphorus metabolic process GO:0051174 43 0.019
synaptic growth at neuromuscular junction GO:0051124 2 0.019
regulation of neural precursor cell proliferation GO:2000177 3 0.019
negative regulation of phosphate metabolic process GO:0045936 13 0.019
chromatin modification GO:0016568 21 0.019
extrinsic apoptotic signaling pathway GO:0097191 3 0.019
positive regulation of nucleic acid templated transcription GO:1903508 57 0.018
cellular macromolecule localization GO:0070727 21 0.018
Fly
rna stabilization GO:0043489 4 0.018
establishment of organelle localization GO:0051656 45 0.018
macromolecular complex subunit organization GO:0043933 74 0.018
Yeast
regulation of protein complex disassembly GO:0043244 1 0.018
negative regulation of i kappab kinase nf kappab signaling GO:0043124 1 0.018
neutrophil extravasation GO:0072672 1 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.018
myofibril assembly GO:0030239 48 0.018
type i interferon production GO:0032606 2 0.018
organelle fusion GO:0048284 3 0.018
positive regulation of neuron death GO:1901216 1 0.018
positive regulation of epithelial cell proliferation GO:0050679 1 0.018
regulation of organelle assembly GO:1902115 4 0.018
dna templated transcription initiation GO:0006352 1 0.018
positive regulation of chromatin modification GO:1903310 1 0.018
gtp catabolic process GO:0006184 2 0.018
cell migration involved in gastrulation GO:0042074 79 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.017
Human Mouse Worm
midbrain development GO:0030901 28 0.017
regulation of erythrocyte differentiation GO:0045646 2 0.017
organic substance transport GO:0071702 58 0.017
Fly
macromolecular complex assembly GO:0065003 35 0.017
rna 3 end processing GO:0031123 2 0.017
negative regulation of mitosis GO:0045839 3 0.017
regulation of cytoplasmic transport GO:1903649 4 0.017
regulation of chromosome segregation GO:0051983 1 0.017
positive regulation of chromosome organization GO:2001252 1 0.017
cellular response to extracellular stimulus GO:0031668 2 0.017
regulation of metal ion transport GO:0010959 4 0.017
rna catabolic process GO:0006401 7 0.017
mitotic nuclear division GO:0007067 18 0.017
Zebrafish
regulation of synapse organization GO:0050807 3 0.017
cell projection morphogenesis GO:0048858 244 0.017
actin filament organization GO:0007015 15 0.017
mitotic cell cycle checkpoint GO:0007093 5 0.017
Fly
positive regulation of apoptotic signaling pathway GO:2001235 1 0.017
circulatory system process GO:0003013 87 0.017
regulation of cell differentiation GO:0045595 142 0.017
Fly
negative regulation of mapk cascade GO:0043409 4 0.017
regulation of anatomical structure morphogenesis GO:0022603 130 0.017
synaptic vesicle recycling GO:0036465 1 0.017
myeloid cell homeostasis GO:0002262 56 0.016
protein localization to plasma membrane GO:0072659 1 0.016
negative regulation of catabolic process GO:0009895 3 0.016
regulation of chromatin organization GO:1902275 5 0.016
establishment of localization in cell GO:0051649 77 0.016
Fly
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.016
Human Mouse Worm
negative regulation of protein metabolic process GO:0051248 16 0.016
gastrulation GO:0007369 208 0.016
heart process GO:0003015 71 0.016
translation GO:0006412 5 0.016
positive regulation of histone modification GO:0031058 1 0.016
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.016
Mouse
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.016
negative regulation of cellular catabolic process GO:0031330 3 0.016
heart contraction GO:0060047 71 0.016
positive regulation of cytoskeleton organization GO:0051495 3 0.016
negative regulation of protein transport GO:0051224 3 0.016
secondary metabolic process GO:0019748 3 0.016
mitochondrion organization GO:0007005 4 0.016
gamete generation GO:0007276 33 0.016
Fly
response to radiation GO:0009314 51 0.016
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.016
ameboidal type cell migration GO:0001667 143 0.016
septum transversum development GO:0003343 4 0.016
meiotic nuclear division GO:0007126 4 0.016
Fly
positive regulation of synapse assembly GO:0051965 1 0.015
lateral inhibition GO:0046331 1 0.015
adult behavior GO:0030534 2 0.015
cellular response to chemical stimulus GO:0070887 157 0.015
Fly
cellular protein complex disassembly GO:0043624 1 0.015
single organism cellular localization GO:1902580 46 0.015
Fly
negative regulation of mitotic cell cycle GO:0045930 11 0.015
Fly
cell cycle g1 s phase transition GO:0044843 1 0.015
positive regulation of signaling GO:0023056 56 0.015
Mouse Rat
gtp metabolic process GO:0046039 4 0.015
cellular response to lipopolysaccharide GO:0071222 3 0.015
regulation of transporter activity GO:0032409 2 0.015
synaptic vesicle localization GO:0097479 1 0.015
brain development GO:0007420 293 0.015
morphogenesis of an epithelium GO:0002009 333 0.015
Fly
protein homooligomerization GO:0051260 3 0.015
actin cytoskeleton organization GO:0030036 63 0.015
growth GO:0040007 174 0.015
nucleoside monophosphate catabolic process GO:0009125 4 0.015
negative regulation of cytokine production GO:0001818 1 0.015
mrna catabolic process GO:0006402 6 0.015
response to other organism GO:0051707 97 0.015
protein complex assembly GO:0006461 30 0.015
cellular response to endogenous stimulus GO:0071495 68 0.015
Fly
centrosome cycle GO:0007098 1 0.015
regulation of intracellular signal transduction GO:1902531 57 0.015
Mouse
phosphorylation GO:0016310 69 0.015
regulation of purine nucleotide catabolic process GO:0033121 2 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.014
protein complex subunit organization GO:0071822 46 0.014
Yeast
negative regulation of chromatin modification GO:1903309 1 0.014
neural nucleus development GO:0048857 15 0.014
cellular macromolecular complex assembly GO:0034622 24 0.014
regulation of filopodium assembly GO:0051489 2 0.014
response to superoxide GO:0000303 2 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.014
synaptic vesicle transport GO:0048489 1 0.014
positive regulation of cell adhesion GO:0045785 1 0.014
programmed cell death GO:0012501 119 0.014
Worm
multicellular organismal reproductive process GO:0048609 35 0.014
Worm Fly
negative regulation of signaling GO:0023057 96 0.014
Fly
regulation of apoptotic process GO:0042981 98 0.014
negative regulation of macromolecule metabolic process GO:0010605 76 0.014
Human Mouse Worm
microtubule based movement GO:0007018 33 0.014
death GO:0016265 121 0.014
Worm
maintenance of cell polarity GO:0030011 5 0.014
rna localization GO:0006403 4 0.014
i kappab kinase nf kappab signaling GO:0007249 4 0.014
Mouse
regulation of protein targeting GO:1903533 2 0.014
response to glucose GO:0009749 3 0.014
negative regulation of nuclear division GO:0051784 3 0.014
phosphorus metabolic process GO:0006793 109 0.014
positive regulation of map kinase activity GO:0043406 3 0.014
negative regulation of biosynthetic process GO:0009890 55 0.014
Human Mouse Worm
regulation of molecular function GO:0065009 70 0.014
Rat
cellular response to stress GO:0033554 62 0.014
Worm Fly
protein depolymerization GO:0051261 1 0.014
spliceosomal snrnp assembly GO:0000387 2 0.014
mrna processing GO:0006397 14 0.014
mitotic cell cycle phase transition GO:0044772 9 0.014
Fly
cellular catabolic process GO:0044248 27 0.014
Rat
cell projection assembly GO:0030031 64 0.014
regulation of cell development GO:0060284 100 0.014
glucose homeostasis GO:0042593 1 0.013
positive regulation of neutrophil extravasation GO:2000391 1 0.013
positive regulation of neuron apoptotic process GO:0043525 1 0.013
cell fate commitment GO:0045165 99 0.013
cell substrate junction assembly GO:0007044 2 0.013
establishment of synaptic vesicle localization GO:0097480 1 0.013
cell matrix adhesion GO:0007160 4 0.013
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.013
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.013
determination of left right asymmetry in nervous system GO:0035545 4 0.013
negative regulation of signal transduction GO:0009968 94 0.013
Fly
lamellipodium organization GO:0097581 1 0.013
regulation of organ growth GO:0046620 3 0.013
regulation of epithelial cell proliferation GO:0050678 3 0.013
gland development GO:0048732 143 0.013
Fly
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.013
rna export from nucleus GO:0006405 1 0.013
positive regulation of striated muscle tissue development GO:0045844 1 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
protein glycosylation GO:0006486 9 0.013
cellular response to external stimulus GO:0071496 2 0.013
melanin metabolic process GO:0006582 2 0.013
intracellular mrna localization GO:0008298 1 0.013
response to bacterium GO:0009617 58 0.013
negative regulation of rna splicing GO:0033119 1 0.013
regulation of multicellular organismal development GO:2000026 223 0.013
Worm Fly
thermosensory behavior GO:0040040 1 0.013
regulation of catalytic activity GO:0050790 55 0.013
histone modification GO:0016570 20 0.013
actin filament based process GO:0030029 64 0.013
response to carbohydrate GO:0009743 3 0.013
guanosine containing compound catabolic process GO:1901069 2 0.013
regulation of actin cytoskeleton organization GO:0032956 8 0.013
glycoprotein biosynthetic process GO:0009101 21 0.012
negative regulation of defense response GO:0031348 2 0.012
single organism localization GO:1902578 225 0.012
Fly
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.012
negative regulation of mrna processing GO:0050686 1 0.012
cellular protein complex localization GO:0034629 1 0.012
mrna splicing via spliceosome GO:0000398 10 0.012

ube2i2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.025
muscular disease DOID:0080000 0 0.025
disease of anatomical entity DOID:7 0 0.025
musculoskeletal system disease DOID:17 0 0.025
muscle tissue disease DOID:66 0 0.025
nervous system disease DOID:863 0 0.021
disease of cellular proliferation DOID:14566 0 0.013