Danio rerio

43 known processes

unc5b

unc-5 homolog B (C. elegans)

(Aliases: unc5h2)

unc5b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
blood vessel development GO:0001568 246 0.860
regulation of multicellular organismal development GO:2000026 223 0.694
vasculature development GO:0001944 278 0.688
sensory organ morphogenesis GO:0090596 200 0.668
cellular component movement GO:0006928 335 0.614
Mouse Rat Worm Fly
locomotion GO:0040011 313 0.580
Mouse Rat Worm Fly
regulation of biological quality GO:0065008 263 0.574
Worm
central nervous system neuron axonogenesis GO:0021955 18 0.567
embryonic viscerocranium morphogenesis GO:0048703 52 0.544
lymph vessel development GO:0001945 27 0.514
cell migration GO:0016477 237 0.508
Worm Fly
ameboidal type cell migration GO:0001667 143 0.498
Worm
sensory organ development GO:0007423 393 0.485
camera type eye morphogenesis GO:0048593 108 0.479
cellular macromolecule biosynthetic process GO:0034645 224 0.462
blood vessel morphogenesis GO:0048514 216 0.452
eye development GO:0001654 277 0.449
muscle cell development GO:0055001 115 0.425
regulation of anatomical structure morphogenesis GO:0022603 130 0.400
heterocycle biosynthetic process GO:0018130 215 0.393
angiogenesis GO:0001525 158 0.392
neural crest cell development GO:0014032 62 0.360
stem cell differentiation GO:0048863 117 0.352
striated muscle cell differentiation GO:0051146 129 0.343
single organism organelle organization GO:1902589 199 0.342
neuron projection development GO:0031175 180 0.333
Mouse Rat Worm Fly
eye morphogenesis GO:0048592 144 0.332
striated muscle cell development GO:0055002 108 0.332
localization of cell GO:0051674 244 0.328
Worm Fly
heart development GO:0007507 313 0.306
cellular component assembly involved in morphogenesis GO:0010927 107 0.302
skeletal system development GO:0001501 181 0.292
regulation of synapse organization GO:0050807 3 0.289
positive regulation of cellular catabolic process GO:0031331 3 0.288
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.284
embryonic limb morphogenesis GO:0030326 2 0.269
positive regulation of catabolic process GO:0009896 4 0.267
embryonic organ development GO:0048568 381 0.266
specification of symmetry GO:0009799 204 0.266
regulation of locomotion GO:0040012 55 0.265
Worm
muscle structure development GO:0061061 196 0.255
single organism metabolic process GO:0044710 217 0.250
regulation of cell shape GO:0008360 1 0.246
neuron differentiation GO:0030182 353 0.244
Mouse Rat Worm Fly
neuron projection morphogenesis GO:0048812 161 0.221
Mouse Rat Worm Fly
brain development GO:0007420 293 0.215
ectodermal placode formation GO:0060788 26 0.213
dorsal ventral pattern formation GO:0009953 125 0.211
reproductive process GO:0022414 40 0.209
Worm
retina development in camera type eye GO:0060041 146 0.205
organic acid metabolic process GO:0006082 31 0.199
regionalization GO:0003002 274 0.193
Fly
regulation of developmental process GO:0050793 247 0.189
regulation of response to stimulus GO:0048583 269 0.187
Human Rat
regulation of synapse assembly GO:0051963 3 0.185
epithelial cell migration GO:0010631 25 0.183
sympathetic nervous system development GO:0048485 3 0.180
regulation of organ growth GO:0046620 3 0.177
cell motility GO:0048870 244 0.177
Worm Fly
heterocycle metabolic process GO:0046483 290 0.176
positive regulation of cellular metabolic process GO:0031325 94 0.176
nitrogen compound metabolic process GO:0006807 319 0.175
lens development in camera type eye GO:0002088 22 0.172
neuron projection guidance GO:0097485 86 0.170
Mouse Rat Worm Fly
regulation of dendrite development GO:0050773 3 0.170
endothelial cell migration GO:0043542 19 0.170
neural crest cell migration GO:0001755 42 0.166
bmp signaling pathway GO:0030509 52 0.163
stem cell development GO:0048864 82 0.163
chordate embryonic development GO:0043009 271 0.162
embryonic eye morphogenesis GO:0048048 30 0.158
axonogenesis GO:0007409 152 0.158
Mouse Rat Worm Fly
organic substance biosynthetic process GO:1901576 289 0.155
embryonic skeletal system morphogenesis GO:0048704 93 0.154
response to abiotic stimulus GO:0009628 122 0.153
striated muscle tissue development GO:0014706 110 0.153
positive regulation of biological process GO:0048518 253 0.153
Human Rat Worm
regulation of nitrogen compound metabolic process GO:0051171 251 0.149
blood coagulation GO:0007596 12 0.147
regulation of cell migration GO:0030334 40 0.144
axon midline choice point recognition GO:0016199 4 0.143
regulation of multicellular organismal process GO:0051239 277 0.141
nucleobase containing compound biosynthetic process GO:0034654 205 0.138
cellular nitrogen compound metabolic process GO:0034641 290 0.136
taxis GO:0042330 109 0.135
Mouse Rat Worm Fly
cytoskeleton organization GO:0007010 96 0.135
cardiac cell fate commitment GO:0060911 1 0.134
cell projection organization GO:0030030 284 0.132
Mouse Rat Worm Fly
protein import GO:0017038 3 0.130
mesenchymal cell development GO:0014031 78 0.128
camera type eye development GO:0043010 222 0.127
modification dependent macromolecule catabolic process GO:0043632 3 0.127
wound healing GO:0042060 90 0.127
regulation of primary metabolic process GO:0080090 311 0.126
neuroblast differentiation GO:0014016 1 0.123
cell substrate adhesion GO:0031589 4 0.120
protein localization to nucleus GO:0034504 3 0.119
embryonic retina morphogenesis in camera type eye GO:0060059 22 0.114
otic vesicle morphogenesis GO:0071600 34 0.113
positive regulation of macromolecule metabolic process GO:0010604 93 0.113
ear morphogenesis GO:0042471 64 0.113
establishment of localization GO:0051234 244 0.113
determination of dorsal ventral asymmetry GO:0048262 34 0.111
small gtpase mediated signal transduction GO:0007264 8 0.108
regulation of metabolic process GO:0019222 359 0.108
regulation of nucleic acid templated transcription GO:1903506 213 0.106
regulation of retina development in camera type eye GO:1902866 2 0.103
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.102
mesenchyme development GO:0060485 127 0.102
positive regulation of nucleic acid templated transcription GO:1903508 57 0.100
negative regulation of mitosis GO:0045839 3 0.097
protein import into nucleus GO:0006606 3 0.097
heart morphogenesis GO:0003007 156 0.097
otic placode formation GO:0043049 23 0.097
regulation of cellular component organization GO:0051128 86 0.097
Worm
cell projection morphogenesis GO:0048858 244 0.096
Mouse Rat Worm Fly
defense response GO:0006952 47 0.094
morphogenesis of an epithelial sheet GO:0002011 49 0.093
central nervous system development GO:0007417 387 0.093
developmental cell growth GO:0048588 52 0.093
Worm
nuclear transport GO:0051169 4 0.093
regulation of macromolecule metabolic process GO:0060255 317 0.092
developmental growth GO:0048589 166 0.092
Worm
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.092
response to stress GO:0006950 263 0.091
positive regulation of cell adhesion GO:0045785 1 0.090
synaptic growth at neuromuscular junction GO:0051124 2 0.089
single organism nuclear import GO:1902593 3 0.089
regulation of cell differentiation GO:0045595 142 0.088
Worm
regulation of cell projection organization GO:0031344 44 0.087
Worm
tissue migration GO:0090130 37 0.087
Worm
regulation of cell development GO:0060284 100 0.087
Worm
regulation of cell motility GO:2000145 46 0.086
positive regulation of multicellular organismal process GO:0051240 52 0.083
Worm
larval development GO:0002164 2 0.083
axon choice point recognition GO:0016198 5 0.083
regulation of neural retina development GO:0061074 2 0.081
fin development GO:0033333 77 0.080
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.079
positive regulation of cellular process GO:0048522 201 0.078
Human Rat Worm
epithelial tube morphogenesis GO:0060562 148 0.078
positive regulation of secretion GO:0051047 1 0.078
axon extension involved in axon guidance GO:0048846 10 0.076
response to oxygen levels GO:0070482 25 0.076
ubiquitin dependent protein catabolic process GO:0006511 3 0.076
ganglion development GO:0061548 5 0.075
regulation of rac protein signal transduction GO:0035020 1 0.075
enzyme linked receptor protein signaling pathway GO:0007167 106 0.075
protein targeting to nucleus GO:0044744 3 0.074
negative regulation of cell projection organization GO:0031345 9 0.074
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.073
cellular protein catabolic process GO:0044257 4 0.072
central nervous system neuron differentiation GO:0021953 74 0.071
head morphogenesis GO:0060323 8 0.069
lateral inhibition GO:0046331 1 0.069
negative regulation of axon extension GO:0030517 7 0.068
regulation of cell morphogenesis GO:0022604 42 0.068
Worm
regulation of transcription involved in cell fate commitment GO:0060850 1 0.068
rna metabolic process GO:0016070 219 0.065
gland development GO:0048732 143 0.064
Fly
skin development GO:0043588 54 0.064
apoptotic process GO:0006915 116 0.064
Human Rat
determination of left right symmetry GO:0007368 179 0.064
morphogenesis of an epithelium GO:0002009 333 0.063
positive regulation of gtp catabolic process GO:0033126 1 0.063
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.063
regulation of macromolecule biosynthetic process GO:0010556 225 0.063
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.063
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.063
pharyngeal system development GO:0060037 18 0.061
ear development GO:0043583 127 0.061
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.061
Mouse Rat Worm Fly
carbohydrate derivative metabolic process GO:1901135 61 0.060
vasculogenesis GO:0001570 41 0.060
response to decreased oxygen levels GO:0036293 25 0.059
regulation of cell substrate adhesion GO:0010810 1 0.059
positive regulation of nucleoside metabolic process GO:0045979 1 0.058
ras protein signal transduction GO:0007265 7 0.058
primary neural tube formation GO:0014020 1 0.058
forebrain generation of neurons GO:0021872 14 0.058
positive regulation of transport GO:0051050 2 0.057
cellular response to organic substance GO:0071310 105 0.057
organelle organization GO:0006996 227 0.056
meiotic cell cycle process GO:1903046 3 0.056
cardioblast migration to the midline involved in heart field formation GO:0060975 7 0.056
positive regulation of signal transduction GO:0009967 56 0.056
Human Rat
transcription dna templated GO:0006351 181 0.056
positive regulation of cellular component biogenesis GO:0044089 3 0.055
axonal defasciculation GO:0007414 2 0.055
positive regulation of gtpase activity GO:0043547 1 0.055
cellular aromatic compound metabolic process GO:0006725 295 0.054
regulation of chronic inflammatory response GO:0002676 1 0.054
neuron projection extension involved in neuron projection guidance GO:1902284 10 0.054
aromatic compound biosynthetic process GO:0019438 217 0.054
regulation of protein glycosylation GO:0060049 3 0.054
regulation of rna biosynthetic process GO:2001141 213 0.054
regulation of protein catabolic process GO:0042176 1 0.054
regulation of protein targeting GO:1903533 2 0.052
axon extension GO:0048675 45 0.052
Worm
multicellular organism growth GO:0035264 4 0.052
guanosine containing compound metabolic process GO:1901068 4 0.052
embryonic skeletal system development GO:0048706 97 0.051
regulation of cellular protein catabolic process GO:1903362 1 0.051
biosynthetic process GO:0009058 294 0.051
cell morphogenesis involved in differentiation GO:0000904 195 0.051
Mouse Rat Worm Fly
organic cyclic compound metabolic process GO:1901360 301 0.051
positive regulation of apoptotic signaling pathway GO:2001235 1 0.051
Rat
cellular component biogenesis GO:0044085 178 0.051
determination of bilateral symmetry GO:0009855 204 0.050
peptidyl serine phosphorylation GO:0018105 1 0.050
positive regulation of developmental process GO:0051094 50 0.050
Worm
protein complex assembly GO:0006461 30 0.050
cellular macromolecule metabolic process GO:0044260 391 0.050
water homeostasis GO:0030104 4 0.050
actin filament based process GO:0030029 64 0.049
lymph vessel morphogenesis GO:0036303 25 0.049
regulation of dendrite morphogenesis GO:0048814 3 0.049
mesenchymal cell differentiation GO:0048762 87 0.049
proteasomal protein catabolic process GO:0010498 2 0.048
negative regulation of kinase activity GO:0033673 4 0.048
oligodendrocyte differentiation GO:0048709 23 0.047
retina morphogenesis in camera type eye GO:0060042 79 0.047
negative regulation of axon guidance GO:1902668 1 0.047
hormone secretion GO:0046879 2 0.046
cellular response to hypoxia GO:0071456 1 0.046
positive regulation of biosynthetic process GO:0009891 68 0.046
notochord cell differentiation GO:0060034 18 0.046
epithelium migration GO:0090132 25 0.045
myelination GO:0042552 18 0.044
regulation of skeletal muscle fiber development GO:0048742 2 0.044
regulation of cellular component movement GO:0051270 55 0.043
cell death GO:0008219 121 0.043
Human Rat
maintenance of location GO:0051235 4 0.042
blood vessel endothelial cell migration GO:0043534 18 0.042
cellular localization GO:0051641 97 0.042
response to endogenous stimulus GO:0009719 83 0.042
stem cell maintenance GO:0019827 4 0.042
outflow tract morphogenesis GO:0003151 1 0.042
protein complex subunit organization GO:0071822 46 0.042
otic vesicle development GO:0071599 42 0.041
morphogenesis of a branching epithelium GO:0061138 16 0.040
regulation of transcription dna templated GO:0006355 213 0.040
negative regulation of protein complex assembly GO:0031333 1 0.040
positive regulation of transcription dna templated GO:0045893 57 0.040
glycoprotein metabolic process GO:0009100 23 0.040
negative regulation of synapse assembly GO:0051964 2 0.039
response to external biotic stimulus GO:0043207 97 0.039
regulation of vasculature development GO:1901342 33 0.039
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.039
inner ear development GO:0048839 126 0.039
cell fate commitment GO:0045165 99 0.038
inner ear morphogenesis GO:0042472 63 0.038
negative regulation of chemotaxis GO:0050922 4 0.037
brain morphogenesis GO:0048854 18 0.037
response to ketone GO:1901654 1 0.037
positive regulation of hydrolase activity GO:0051345 13 0.037
developmental growth involved in morphogenesis GO:0060560 86 0.036
Worm
negative regulation of neuron projection development GO:0010977 9 0.036
embryonic organ morphogenesis GO:0048562 274 0.036
regulation of apoptotic process GO:0042981 98 0.036
Human Rat
cell growth GO:0016049 57 0.036
Worm
anatomical structure homeostasis GO:0060249 36 0.035
nuclear import GO:0051170 3 0.035
positive regulation of gene expression GO:0010628 71 0.035
cell cycle g1 s phase transition GO:0044843 1 0.035
stem cell fate commitment GO:0048865 1 0.035
regulation of rho protein signal transduction GO:0035023 2 0.035
cardiocyte differentiation GO:0035051 44 0.034
cell morphogenesis GO:0000902 289 0.034
Mouse Rat Worm Fly
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.034
response to bacterium GO:0009617 58 0.034
regeneration GO:0031099 91 0.034
neuron recognition GO:0008038 18 0.034
establishment of protein localization to organelle GO:0072594 4 0.034
lymphangiogenesis GO:0001946 25 0.033
interaction with host GO:0051701 4 0.033
regulation of hormone secretion GO:0046883 2 0.033
extracellular structure organization GO:0043062 27 0.033
diencephalon development GO:0021536 58 0.033
peripheral nervous system development GO:0007422 55 0.033
regulation of synapse structure and activity GO:0050803 5 0.033
macromolecule biosynthetic process GO:0009059 227 0.033
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.033
Worm
regulation of cellular component biogenesis GO:0044087 12 0.032
somatic stem cell maintenance GO:0035019 1 0.032
positive regulation of bmp signaling pathway GO:0030513 10 0.032
neuron projection extension GO:1990138 45 0.032
Worm
autonomic nervous system development GO:0048483 19 0.032
protein metabolic process GO:0019538 183 0.032
Worm
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.032
response to wounding GO:0009611 116 0.032
negative regulation of axonogenesis GO:0050771 7 0.032
gene expression GO:0010467 252 0.031
response to other organism GO:0051707 97 0.031
embryonic heart tube development GO:0035050 133 0.031
embryonic heart tube morphogenesis GO:0003143 108 0.031
skeletal system morphogenesis GO:0048705 102 0.030
cardioblast migration GO:0003260 7 0.030
synapse organization GO:0050808 21 0.030
cellular response to oxygen levels GO:0071453 1 0.030
regulation of chemotaxis GO:0050920 18 0.030
positive regulation of rna metabolic process GO:0051254 59 0.030
biological adhesion GO:0022610 40 0.030
multi organism process GO:0051704 134 0.030
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.030
negative regulation of locomotion GO:0040013 18 0.030
cellular amine metabolic process GO:0044106 2 0.029
regulation of anatomical structure size GO:0090066 33 0.029
Worm
negative regulation of cell motility GO:2000146 17 0.029
regulation of autophagy GO:0010506 3 0.029
positive regulation of glial cell differentiation GO:0045687 1 0.029
positive regulation of cell matrix adhesion GO:0001954 1 0.029
rac protein signal transduction GO:0016601 1 0.029
intracellular transport GO:0046907 32 0.028
negative regulation of histone modification GO:0031057 1 0.028
establishment of localization in cell GO:0051649 77 0.028
glial cell differentiation GO:0010001 42 0.028
gtp metabolic process GO:0046039 4 0.028
organic substance transport GO:0071702 58 0.028
negative regulation of programmed cell death GO:0043069 58 0.028
Human
gliogenesis GO:0042063 45 0.027
Fly
anterior posterior axon guidance GO:0033564 5 0.027
Mouse
embryonic camera type eye development GO:0031076 29 0.027
developmental programmed cell death GO:0010623 4 0.027
modification dependent protein catabolic process GO:0019941 3 0.027
regulation of protein localization to nucleus GO:1900180 2 0.027
regulation of intracellular signal transduction GO:1902531 57 0.026
Human
neural crest cell differentiation GO:0014033 72 0.026
negative regulation of ras protein signal transduction GO:0046580 1 0.026
cellular response to decreased oxygen levels GO:0036294 1 0.026
regulation of gene expression GO:0010468 265 0.026
regulation of angiogenesis GO:0045765 26 0.026
entrainment of circadian clock GO:0009649 2 0.026
cognition GO:0050890 1 0.026
canonical wnt signaling pathway GO:0060070 48 0.026
cellular biosynthetic process GO:0044249 286 0.026
muscle tissue development GO:0060537 110 0.026
embryonic cranial skeleton morphogenesis GO:0048701 90 0.025
cell fate specification involved in pattern specification GO:0060573 3 0.025
regulation of programmed cell death GO:0043067 101 0.025
Human Rat
guanosine containing compound catabolic process GO:1901069 2 0.025
neuroblast fate commitment GO:0014017 1 0.025
single organism cell adhesion GO:0098602 29 0.024
cellular component assembly GO:0022607 170 0.024
glial cell development GO:0021782 20 0.024
gtp catabolic process GO:0006184 2 0.024
homeostatic process GO:0042592 142 0.024
regulation of epithelial cell migration GO:0010632 5 0.024
negative regulation of biological process GO:0048519 304 0.024
fin morphogenesis GO:0033334 53 0.024
retinal ganglion cell axon guidance GO:0031290 35 0.024
spinal cord development GO:0021510 46 0.024
cardiac muscle tissue development GO:0048738 48 0.024
cellular lipid metabolic process GO:0044255 36 0.024
macromolecular complex subunit organization GO:0043933 74 0.024
synaptic target recognition GO:0008039 1 0.024
regulation of circadian rhythm GO:0042752 4 0.024
otic vesicle formation GO:0030916 27 0.023
cell migration involved in heart formation GO:0060974 10 0.023
organelle assembly GO:0070925 110 0.023
forebrain development GO:0030900 96 0.023
central nervous system projection neuron axonogenesis GO:0021952 15 0.023
cell fate specification GO:0001708 68 0.022
cellular hormone metabolic process GO:0034754 19 0.022
hepatocyte proliferation GO:0072574 2 0.022
positive regulation of nucleotide catabolic process GO:0030813 1 0.022
regulation of epithelial cell proliferation GO:0050678 3 0.022
negative regulation of epithelial cell proliferation GO:0050680 1 0.022
regulation of protein transport GO:0051223 3 0.022
negative regulation of cellular metabolic process GO:0031324 77 0.022
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.022
regulation of cellular metabolic process GO:0031323 320 0.021
detection of temperature stimulus GO:0016048 0 0.021
regulation of neuron projection development GO:0010975 40 0.021
Worm
single organism localization GO:1902578 225 0.021
forebrain cell migration GO:0021885 1 0.021
heart looping GO:0001947 94 0.021
heart formation GO:0060914 13 0.021
regulation of multicellular organism growth GO:0040014 4 0.021
regulation of localization GO:0032879 104 0.021
intracellular signal transduction GO:0035556 85 0.021
Human
negative regulation of chromosome organization GO:2001251 1 0.021
positive regulation of cell cycle GO:0045787 3 0.021
carboxylic acid metabolic process GO:0019752 22 0.020
cell surface receptor signaling pathway GO:0007166 325 0.020
Human Rat
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.020
negative regulation of cell morphogenesis involved in differentiation GO:0010771 8 0.020
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.020
regulation of intracellular protein transport GO:0033157 3 0.020
small molecule catabolic process GO:0044282 3 0.020
regulation of cell size GO:0008361 29 0.020
Worm
regulation of skeletal muscle tissue development GO:0048641 4 0.020
regulation of biomineral tissue development GO:0070167 2 0.020
proteolysis GO:0006508 38 0.020
rna biosynthetic process GO:0032774 181 0.020
regulation of axon guidance GO:1902667 8 0.020
regulation of axon extension involved in axon guidance GO:0048841 6 0.020
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.019
renal system development GO:0072001 94 0.019
negative regulation of rho protein signal transduction GO:0035024 1 0.019
regulation of cellular amine metabolic process GO:0033238 0 0.019
muscle cell proliferation GO:0033002 7 0.019
negative regulation of cell migration GO:0030336 17 0.019
regulation of gtp catabolic process GO:0033124 2 0.019
septum transversum development GO:0003343 4 0.019
positive regulation of molecular function GO:0044093 33 0.019
convergent extension GO:0060026 118 0.019
aging GO:0007568 2 0.019
negative chemotaxis GO:0050919 1 0.018
negative regulation of cell differentiation GO:0045596 46 0.018
regulation of gtpase activity GO:0043087 2 0.018
response to hypoxia GO:0001666 25 0.018
actin cytoskeleton organization GO:0030036 63 0.018
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.018
organonitrogen compound metabolic process GO:1901564 74 0.018
endocardial progenitor cell migration to the midline involved in heart field formation GO:0003262 4 0.018
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.018
germ line stem cell maintenance GO:0030718 2 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
neuroblast fate determination GO:0007400 1 0.018
negative regulation of nuclear division GO:0051784 3 0.018
amine metabolic process GO:0009308 2 0.018
positive regulation of phospholipase c activity GO:0010863 1 0.018
lymphatic endothelial cell differentiation GO:0060836 1 0.018
apoptotic process involved in development GO:1902742 2 0.018
negative regulation of nervous system development GO:0051961 22 0.018
neuroblast proliferation GO:0007405 2 0.018
negative regulation of protein kinase activity GO:0006469 4 0.018
regulation of stem cell proliferation GO:0072091 2 0.018
regulation of cellular response to growth factor stimulus GO:0090287 35 0.018
cell type specific apoptotic process GO:0097285 22 0.018
Human
cell projection assembly GO:0030031 64 0.018
motor neuron axon guidance GO:0008045 23 0.017
Worm Fly
ensheathment of neurons GO:0007272 18 0.017
axon guidance GO:0007411 86 0.017
Mouse Rat Worm Fly
regulation of establishment of protein localization GO:0070201 4 0.017
positive regulation of response to external stimulus GO:0032103 9 0.017
lamellipodium assembly GO:0030032 1 0.017
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 10 0.017
pectoral fin development GO:0033339 50 0.017
negative regulation of cellular component movement GO:0051271 18 0.017
hormone transport GO:0009914 2 0.017
response to external stimulus GO:0009605 264 0.017
Mouse Rat Worm Fly
regulation of nucleoside metabolic process GO:0009118 2 0.017
cellular response to chemical stimulus GO:0070887 157 0.017
regulation of molecular function GO:0065009 70 0.017
direct ossification GO:0036072 3 0.017
small molecule metabolic process GO:0044281 77 0.017
system process GO:0003008 185 0.017
endocrine process GO:0050886 2 0.016
production of molecular mediator of immune response GO:0002440 2 0.016
cell proliferation in forebrain GO:0021846 3 0.016
epithelial cell development GO:0002064 42 0.016
negative regulation of chromatin modification GO:1903309 1 0.016
embryonic camera type eye morphogenesis GO:0048596 19 0.016
regulation of axon extension GO:0030516 24 0.016
Worm
positive regulation of map kinase activity GO:0043406 3 0.016
central nervous system neuron development GO:0021954 29 0.016
regulation of ras gtpase activity GO:0032318 2 0.016
optic cup morphogenesis involved in camera type eye development GO:0002072 7 0.016
generation of neurons GO:0048699 385 0.016
Mouse Rat Worm Fly
gabaergic neuron differentiation GO:0097154 2 0.016
positive regulation of cellular biosynthetic process GO:0031328 68 0.016
actomyosin structure organization GO:0031032 53 0.016
lipid catabolic process GO:0016042 4 0.016
spemann organizer formation at the embryonic shield GO:0060063 2 0.015
regulation of rna metabolic process GO:0051252 224 0.015
neuron development GO:0048666 262 0.015
Mouse Rat Worm Fly
cilium organization GO:0044782 71 0.015
coagulation GO:0050817 13 0.015
nucleic acid metabolic process GO:0090304 244 0.015
positive regulation of response to stimulus GO:0048584 80 0.015
Human Rat
cellular protein metabolic process GO:0044267 129 0.015
regulation of response to external stimulus GO:0032101 31 0.015
microtubule based process GO:0007017 60 0.015
regulation of bmp signaling pathway GO:0030510 39 0.015
negative regulation of bmp signaling pathway GO:0030514 13 0.015
immune system development GO:0002520 191 0.015
positive regulation of secretion by cell GO:1903532 1 0.015
regulation of cell death GO:0010941 103 0.015
Human Rat
regulation of biosynthetic process GO:0009889 250 0.015
endocardial cushion formation GO:0003272 2 0.015
regulation of protein import into nucleus GO:0042306 2 0.015
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 3 0.015

unc5b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.096
disease of metabolism DOID:0014667 0 0.084
amyloidosis DOID:9120 0 0.084
acquired metabolic disease DOID:0060158 0 0.084
bone development disease DOID:0080006 0 0.078
bone disease DOID:0080001 0 0.078
dysostosis DOID:1934 0 0.078
musculoskeletal system disease DOID:17 0 0.078
connective tissue disease DOID:65 0 0.078
synostosis DOID:11971 0 0.063
sensory system disease DOID:0050155 0 0.015
eye and adnexa disease DOID:1492 0 0.015
nervous system disease DOID:863 0 0.015
eye disease DOID:5614 0 0.015