Danio rerio

39 known processes

upf1

upf1 regulator of nonsense transcripts homolog (yeast)

(Aliases: wu:fj48a01,wu:fi40f07,zgc:55472,rent1)

upf1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 4 0.856
cellular macromolecule metabolic process GO:0044260 391 0.583
mrna catabolic process GO:0006402 6 0.538
nuclear transcribed mrna catabolic process GO:0000956 4 0.424
rna catabolic process GO:0006401 7 0.297
regulation of cellular metabolic process GO:0031323 320 0.253
Human
nucleic acid metabolic process GO:0090304 244 0.252
rna metabolic process GO:0016070 219 0.243
organelle organization GO:0006996 227 0.220
regulation of nitrogen compound metabolic process GO:0051171 251 0.199
organic substance catabolic process GO:1901575 28 0.189
nucleobase containing compound metabolic process GO:0006139 274 0.170
larval development GO:0002164 2 0.160
embryo development ending in birth or egg hatching GO:0009792 271 0.156
regulation of macromolecule metabolic process GO:0060255 317 0.147
Human Mouse Worm
signal transduction GO:0007165 455 0.144
nucleic acid templated transcription GO:0097659 181 0.138
heterocycle metabolic process GO:0046483 290 0.130
cellular aromatic compound metabolic process GO:0006725 295 0.127
regulation of rna biosynthetic process GO:2001141 213 0.127
response to chemical GO:0042221 320 0.125
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.123
regulation of rna metabolic process GO:0051252 224 0.116
regulation of macromolecule biosynthetic process GO:0010556 225 0.116
Human
regulation of establishment of protein localization GO:0070201 4 0.116
establishment of localization GO:0051234 244 0.115
nuclear transport GO:0051169 4 0.106
organic cyclic compound metabolic process GO:1901360 301 0.105
mrna metabolic process GO:0016071 20 0.096
cellular ketone metabolic process GO:0042180 11 0.092
regulation of oocyte development GO:0060281 3 0.092
positive regulation of transport GO:0051050 2 0.088
regulation of metabolic process GO:0019222 359 0.087
Human Mouse Worm
cellular nitrogen compound metabolic process GO:0034641 290 0.086
embryonic organ development GO:0048568 381 0.086
Worm
peptidyl serine phosphorylation GO:0018105 1 0.085
cellular nitrogen compound biosynthetic process GO:0044271 218 0.084
positive regulation of signal transduction GO:0009967 56 0.083
maintenance of location GO:0051235 4 0.083
aging GO:0007568 2 0.082
regulation of cellular biosynthetic process GO:0031326 245 0.082
Human
macromolecule biosynthetic process GO:0009059 227 0.080
Human
nitrogen compound metabolic process GO:0006807 319 0.080
tube morphogenesis GO:0035239 349 0.078
regulation of gene expression GO:0010468 265 0.078
Human Mouse Worm
meiotic nuclear division GO:0007126 4 0.078
regulation of primary metabolic process GO:0080090 311 0.077
Human
axon development GO:0061564 166 0.077
locomotion GO:0040011 313 0.077
neuroblast proliferation GO:0007405 2 0.076
modification dependent protein catabolic process GO:0019941 3 0.075
regulation of mrna splicing via spliceosome GO:0048024 3 0.074
nucleocytoplasmic transport GO:0006913 4 0.074
negative regulation of signal transduction GO:0009968 94 0.073
regulation of signal transduction GO:0009966 225 0.071
rna splicing GO:0008380 16 0.071
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.070
rna biosynthetic process GO:0032774 181 0.070
peptidyl serine modification GO:0018209 2 0.066
positive regulation of biological process GO:0048518 253 0.065
cellular component biogenesis GO:0044085 178 0.064
regulation of protein catabolic process GO:0042176 1 0.062
regulation of nucleic acid templated transcription GO:1903506 213 0.061
cellular protein catabolic process GO:0044257 4 0.060
regulation of response to stimulus GO:0048583 269 0.059
regulation of nucleocytoplasmic transport GO:0046822 2 0.059
neuron differentiation GO:0030182 353 0.059
negative regulation of biological process GO:0048519 304 0.059
Worm
growth GO:0040007 174 0.058
positive regulation of cellular process GO:0048522 201 0.057
alternative mrna splicing via spliceosome GO:0000380 1 0.056
cellular macromolecule biosynthetic process GO:0034645 224 0.055
Human
modification dependent macromolecule catabolic process GO:0043632 3 0.055
regulation of protein targeting GO:1903533 2 0.055
regulation of cellular ketone metabolic process GO:0010565 7 0.055
chordate embryonic development GO:0043009 271 0.054
nucleobase containing compound biosynthetic process GO:0034654 205 0.054
protein localization to nucleus GO:0034504 3 0.054
cellular amine metabolic process GO:0044106 2 0.054
generation of neurons GO:0048699 385 0.052
regulation of protein transport GO:0051223 3 0.052
regulation of mrna processing GO:0050684 3 0.052
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.052
regulation of intracellular protein transport GO:0033157 3 0.050
regulation of multicellular organismal process GO:0051239 277 0.049
cellular catabolic process GO:0044248 27 0.048
transport GO:0006810 220 0.048
transcription dna templated GO:0006351 181 0.048
regulation of meiotic cell cycle GO:0051445 1 0.048
cellular component movement GO:0006928 335 0.048
cell surface receptor signaling pathway GO:0007166 325 0.048
gene expression GO:0010467 252 0.047
Human Mouse Worm
single organism reproductive process GO:0044702 40 0.047
Worm
single organism organelle organization GO:1902589 199 0.046
organic cyclic compound biosynthetic process GO:1901362 223 0.045
fertilization GO:0009566 3 0.045
neuron development GO:0048666 262 0.045
positive regulation of cellular metabolic process GO:0031325 94 0.045
cartilage development GO:0051216 96 0.045
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.045
lateral inhibition GO:0046331 1 0.045
cellular response to organic substance GO:0071310 105 0.044
regulation of cellular protein catabolic process GO:1903362 1 0.044
regionalization GO:0003002 274 0.043
regulation of protein ubiquitination GO:0031396 3 0.043
regulation of cellular amine metabolic process GO:0033238 0 0.043
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.042
Human
amine metabolic process GO:0009308 2 0.042
response to stress GO:0006950 263 0.042
Human
positive regulation of catabolic process GO:0009896 4 0.042
carboxylic acid metabolic process GO:0019752 22 0.042
single organism localization GO:1902578 225 0.042
regulation of developmental process GO:0050793 247 0.041
tube closure GO:0060606 1 0.041
regulation of cellular component organization GO:0051128 86 0.041
Human
response to endogenous stimulus GO:0009719 83 0.040
digestive tract mesoderm development GO:0007502 1 0.040
organic substance biosynthetic process GO:1901576 289 0.039
Human
lipid storage GO:0019915 1 0.038
protein complex biogenesis GO:0070271 30 0.038
regulation of cellular amino acid metabolic process GO:0006521 0 0.038
phosphorus metabolic process GO:0006793 109 0.038
Human
phagocytosis GO:0006909 3 0.037
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.037
establishment of protein localization to organelle GO:0072594 4 0.037
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.037
digestive system development GO:0055123 289 0.036
multicellular organism growth GO:0035264 4 0.036
positive regulation of cellular catabolic process GO:0031331 3 0.036
negative regulation of chromosome organization GO:2001251 1 0.036
peptidyl threonine phosphorylation GO:0018107 1 0.036
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.036
cellular response to extracellular stimulus GO:0031668 2 0.036
digestive tract morphogenesis GO:0048546 231 0.035
aromatic compound biosynthetic process GO:0019438 217 0.035
adherens junction maintenance GO:0034334 2 0.035
cellular biosynthetic process GO:0044249 286 0.035
Human
cellular response to nutrient levels GO:0031669 2 0.035
regulation of protein complex assembly GO:0043254 3 0.035
stem cell fate commitment GO:0048865 1 0.034
positive regulation of cellular amine metabolic process GO:0033240 0 0.034
mitotic cell cycle process GO:1903047 48 0.034
chemotaxis GO:0006935 104 0.034
regulation of organelle organization GO:0033043 29 0.033
regulation of response to cytokine stimulus GO:0060759 3 0.033
regulation of cell communication GO:0010646 232 0.033
positive regulation of cell cycle GO:0045787 3 0.032
negative regulation of cellular metabolic process GO:0031324 77 0.032
regulation of biosynthetic process GO:0009889 250 0.032
Human
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.032
actin cytoskeleton organization GO:0030036 63 0.031
lipid metabolic process GO:0006629 52 0.031
positive regulation of cell adhesion GO:0045785 1 0.031
positive regulation of rna metabolic process GO:0051254 59 0.031
negative regulation of cytoplasmic transport GO:1903650 2 0.031
regulation of reproductive process GO:2000241 4 0.031
transcription from rna polymerase ii promoter GO:0006366 80 0.031
cellular amino acid metabolic process GO:0006520 7 0.030
epithelial tube morphogenesis GO:0060562 148 0.030
response to external stimulus GO:0009605 264 0.030
regulation of protein import into nucleus GO:0042306 2 0.030
positive regulation of cellular biosynthetic process GO:0031328 68 0.030
single organism nuclear import GO:1902593 3 0.030
positive regulation of response to stimulus GO:0048584 80 0.030
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.029
positive regulation of metabolic process GO:0009893 108 0.029
protein modification process GO:0036211 100 0.029
response to organic substance GO:0010033 153 0.029
protein import GO:0017038 3 0.029
myeloid cell differentiation GO:0030099 86 0.029
cellular response to chemical stimulus GO:0070887 157 0.029
developmental growth GO:0048589 166 0.028
digestive tract development GO:0048565 265 0.028
oxoacid metabolic process GO:0043436 31 0.028
cell morphogenesis GO:0000902 289 0.028
cellular macromolecule catabolic process GO:0044265 12 0.028
actin filament polymerization GO:0030041 2 0.028
multi organism reproductive process GO:0044703 36 0.027
organic acid metabolic process GO:0006082 31 0.027
single organism transport GO:0044765 206 0.027
cellular component assembly GO:0022607 170 0.027
glucose homeostasis GO:0042593 1 0.027
positive regulation of cellular component biogenesis GO:0044089 3 0.026
ubiquitin dependent protein catabolic process GO:0006511 3 0.026
small molecule catabolic process GO:0044282 3 0.026
regulation of transcription dna templated GO:0006355 213 0.026
actin filament based process GO:0030029 64 0.026
synaptic growth at neuromuscular junction GO:0051124 2 0.026
cell migration GO:0016477 237 0.026
primary neural tube formation GO:0014020 1 0.026
transmembrane transport GO:0055085 120 0.025
mitotic cell cycle GO:0000278 64 0.025
negative regulation of protein kinase activity GO:0006469 4 0.025
negative regulation of dna metabolic process GO:0051053 4 0.025
adult behavior GO:0030534 2 0.025
cell part morphogenesis GO:0032990 246 0.025
protein dephosphorylation GO:0006470 3 0.025
heterocycle biosynthetic process GO:0018130 215 0.024
actin polymerization or depolymerization GO:0008154 2 0.024
peptidyl threonine modification GO:0018210 1 0.024
somatic muscle development GO:0007525 4 0.024
regulation of cytoplasmic transport GO:1903649 4 0.024
stem cell maintenance GO:0019827 4 0.024
purine nucleoside monophosphate catabolic process GO:0009128 4 0.024
Human
actin filament organization GO:0007015 15 0.024
localization of cell GO:0051674 244 0.024
macromolecule catabolic process GO:0009057 15 0.024
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.023
anterior posterior pattern specification GO:0009952 152 0.023
nuclear import GO:0051170 3 0.023
gtp catabolic process GO:0006184 2 0.023
small molecule metabolic process GO:0044281 77 0.023
Human
wnt signaling pathway GO:0016055 80 0.023
peptide transport GO:0015833 1 0.023
negative regulation of protein phosphorylation GO:0001933 4 0.023
positive regulation of notch signaling pathway GO:0045747 3 0.022
synaptic target recognition GO:0008039 1 0.022
positive regulation of rna biosynthetic process GO:1902680 57 0.022
protein metabolic process GO:0019538 183 0.022
Human
regulation of signaling GO:0023051 235 0.022
adherens junction organization GO:0034332 4 0.022
negative regulation of cellular process GO:0048523 283 0.022
positive regulation of transcription dna templated GO:0045893 57 0.021
retina development in camera type eye GO:0060041 146 0.021
ameboidal type cell migration GO:0001667 143 0.021
macromolecular complex subunit organization GO:0043933 74 0.021
Human
hindbrain development GO:0030902 91 0.021
extrinsic apoptotic signaling pathway GO:0097191 3 0.021
positive regulation of gene expression GO:0010628 71 0.021
positive regulation of translation GO:0045727 1 0.021
single organism metabolic process GO:0044710 217 0.021
Human
positive regulation of nucleic acid templated transcription GO:1903508 57 0.021
locomotor rhythm GO:0045475 3 0.021
regulation of response to nutrient levels GO:0032107 1 0.021
neuron projection development GO:0031175 180 0.021
biosynthetic process GO:0009058 294 0.021
Human
connective tissue development GO:0061448 99 0.021
carboxylic acid catabolic process GO:0046395 3 0.020
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.020
negative regulation of rna metabolic process GO:0051253 48 0.020
negative regulation of histone modification GO:0031057 1 0.020
regulation of multicellular organism growth GO:0040014 4 0.020
cellular localization GO:0051641 97 0.020
fatty acid oxidation GO:0019395 1 0.020
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.020
pronuclear migration GO:0035046 1 0.020
regulation of nucleoside metabolic process GO:0009118 2 0.020
regulation of purine nucleotide catabolic process GO:0033121 2 0.020
stem cell development GO:0048864 82 0.020
organelle localization GO:0051640 49 0.020
gtp metabolic process GO:0046039 4 0.020
determination of bilateral symmetry GO:0009855 204 0.020
positive regulation of jun kinase activity GO:0043507 2 0.019
cell cycle g1 s phase transition GO:0044843 1 0.019
post embryonic organ development GO:0048569 4 0.019
response to glucose GO:0009749 3 0.019
regulation of fatty acid metabolic process GO:0019217 1 0.019
multi organism process GO:0051704 134 0.019
protein targeting to nucleus GO:0044744 3 0.019
endodermal cell differentiation GO:0035987 19 0.019
cell projection morphogenesis GO:0048858 244 0.019
positive regulation of apoptotic signaling pathway GO:2001235 1 0.019
membrane invagination GO:0010324 1 0.019
regulation of molecular function GO:0065009 70 0.019
autophagy GO:0006914 4 0.019
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 10 0.019
glucose import GO:0046323 2 0.019
protein complex assembly GO:0006461 30 0.019
vesicle mediated transport GO:0016192 22 0.019
spermatid development GO:0007286 2 0.019
cell cycle GO:0007049 93 0.018
cellular protein modification process GO:0006464 100 0.018
embryonic skeletal joint development GO:0072498 3 0.018
immune system development GO:0002520 191 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.018
regulation of protein localization to nucleus GO:1900180 2 0.018
single fertilization GO:0007338 3 0.018
cellular response to external stimulus GO:0071496 2 0.018
energy reserve metabolic process GO:0006112 2 0.018
regulation of synapse assembly GO:0051963 3 0.018
nuclear migration GO:0007097 3 0.018
negative regulation of cell communication GO:0010648 96 0.018
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.018
specification of symmetry GO:0009799 204 0.018
developmental process involved in reproduction GO:0003006 27 0.017
Worm
cellular response to starvation GO:0009267 1 0.017
negative regulation of cellular catabolic process GO:0031330 3 0.017
single organism cellular localization GO:1902580 46 0.017
negative chemotaxis GO:0050919 1 0.017
mesenchymal cell development GO:0014031 78 0.017
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.017
regulation of rho protein signal transduction GO:0035023 2 0.017
skeletal system development GO:0001501 181 0.017
mrna splicing via spliceosome GO:0000398 10 0.017
regulation of apoptotic process GO:0042981 98 0.017
cellular lipid metabolic process GO:0044255 36 0.017
skin development GO:0043588 54 0.017
stem cell proliferation GO:0072089 4 0.017
response to nutrient GO:0007584 3 0.017
macromolecule modification GO:0043412 111 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.017
gastrulation with mouth forming second GO:0001702 44 0.017
single organism membrane fusion GO:0044801 2 0.017
multicellular organism reproduction GO:0032504 35 0.016
oocyte maturation GO:0001556 4 0.016
negative regulation of metabolic process GO:0009892 86 0.016
Worm
organonitrogen compound metabolic process GO:1901564 74 0.016
Human
cell motility GO:0048870 244 0.016
carbohydrate homeostasis GO:0033500 1 0.016
behavior GO:0007610 74 0.016
positive regulation of protein complex assembly GO:0031334 2 0.016
embryonic skeletal system morphogenesis GO:0048704 93 0.016
cellular protein metabolic process GO:0044267 129 0.016
Human
rna processing GO:0006396 25 0.016
lamellipodium assembly GO:0030032 1 0.016
negative regulation of macromolecule metabolic process GO:0010605 76 0.016
Worm
cardiac cell fate commitment GO:0060911 1 0.016
response to uv GO:0009411 3 0.015
negative regulation of map kinase activity GO:0043407 2 0.015
sensory organ development GO:0007423 393 0.015
morphogenesis of an epithelium GO:0002009 333 0.015
regulation of response to extracellular stimulus GO:0032104 1 0.015
protein import into nucleus GO:0006606 3 0.015
establishment of organelle localization GO:0051656 45 0.015
response to carbohydrate GO:0009743 3 0.015
positive regulation of chromosome organization GO:2001252 1 0.015
development of primary female sexual characteristics GO:0046545 4 0.015
wnt signaling pathway planar cell polarity pathway GO:0060071 4 0.015
regulation of cell shape GO:0008360 1 0.015
protein homooligomerization GO:0051260 3 0.015
positive regulation of map kinase activity GO:0043406 3 0.015
negative regulation of kinase activity GO:0033673 4 0.015
negative regulation of cytokine mediated signaling pathway GO:0001960 2 0.015
macromolecule localization GO:0033036 54 0.015
canonical wnt signaling pathway GO:0060070 48 0.015
cellular response to stress GO:0033554 62 0.015
Human
negative regulation of catabolic process GO:0009895 3 0.015
sexual reproduction GO:0019953 36 0.015
regulation of biological quality GO:0065008 263 0.015
eye development GO:0001654 277 0.015
regulation of synapse organization GO:0050807 3 0.015
establishment of localization in cell GO:0051649 77 0.014
microtubule cytoskeleton organization GO:0000226 33 0.014
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.014
negative regulation of cytokine production GO:0001818 1 0.014
cellular response to lipopolysaccharide GO:0071222 3 0.014
axonogenesis GO:0007409 152 0.014
cytoskeleton organization GO:0007010 96 0.014
atp catabolic process GO:0006200 4 0.014
Human
positive regulation of stress activated mapk cascade GO:0032874 3 0.014
regulation of dendrite development GO:0050773 3 0.014
response to corticosteroid GO:0031960 1 0.014
establishment of apical basal cell polarity GO:0035089 2 0.014
response to oxygen containing compound GO:1901700 55 0.014
negative regulation of stem cell differentiation GO:2000737 2 0.014
neuron projection morphogenesis GO:0048812 161 0.014
mrna processing GO:0006397 14 0.014
regulation of type i interferon production GO:0032479 2 0.014
embryonic heart tube development GO:0035050 133 0.014
endoderm formation GO:0001706 29 0.014
regulation of gtp catabolic process GO:0033124 2 0.014
cellular carbohydrate metabolic process GO:0044262 4 0.014
somatic stem cell maintenance GO:0035019 1 0.014
response to alkaloid GO:0043279 2 0.014
system process GO:0003008 185 0.014
posttranscriptional regulation of gene expression GO:0010608 14 0.014
Human Worm
female sex differentiation GO:0046660 4 0.014
mitotic dna integrity checkpoint GO:0044774 4 0.014
erythrocyte differentiation GO:0030218 54 0.014
negative regulation of mitosis GO:0045839 3 0.014
cell proliferation GO:0008283 80 0.014
positive regulation of biosynthetic process GO:0009891 68 0.014
positive regulation of signaling GO:0023056 56 0.014
rna splicing via transesterification reactions GO:0000375 10 0.014
intracellular signal transduction GO:0035556 85 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.013
Human
cellular response to endogenous stimulus GO:0071495 68 0.013
cellular response to molecule of bacterial origin GO:0071219 3 0.013
female gonad development GO:0008585 4 0.013
regulation of glucose transport GO:0010827 1 0.013
cellular response to biotic stimulus GO:0071216 3 0.013
regulation of erk1 and erk2 cascade GO:0070372 4 0.013
protein stabilization GO:0050821 2 0.013
enzyme linked receptor protein signaling pathway GO:0007167 106 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
phosphate containing compound metabolic process GO:0006796 108 0.013
Human
regulation of proteolysis GO:0030162 24 0.013
heart development GO:0007507 313 0.013
phosphorylation GO:0016310 69 0.013
hemopoiesis GO:0030097 183 0.013
cellular response to hormone stimulus GO:0032870 39 0.013
appendage morphogenesis GO:0035107 56 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.013
angioblast cell migration involved in selective angioblast sprouting GO:0035475 4 0.013
meiotic cell cycle process GO:1903046 3 0.013
erk1 and erk2 cascade GO:0070371 4 0.012
cell cycle process GO:0022402 53 0.012
negative regulation of nuclear division GO:0051784 3 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
embryonic organ morphogenesis GO:0048562 274 0.012
Worm
multicellular organismal reproductive process GO:0048609 35 0.012
catabolic process GO:0009056 32 0.012
camera type eye development GO:0043010 222 0.012
nuclear division GO:0000280 23 0.012
determination of heart left right asymmetry GO:0061371 117 0.012
posttranscriptional gene silencing by rna GO:0035194 3 0.012
Worm
regulation of glucose import GO:0046324 1 0.012
embryonic cranial skeleton morphogenesis GO:0048701 90 0.012
macroautophagy GO:0016236 1 0.012
regulation of mitotic cell cycle GO:0007346 25 0.012
rna 3 end processing GO:0031123 2 0.012
stem cell division GO:0017145 1 0.012
stem cell differentiation GO:0048863 117 0.012
spermatid differentiation GO:0048515 2 0.012
ear morphogenesis GO:0042471 64 0.012
protein localization GO:0008104 40 0.012
heterocycle catabolic process GO:0046700 15 0.012
positive regulation of glucose transport GO:0010828 1 0.012
transcription from rna polymerase iii promoter GO:0006383 1 0.011
gene silencing by rna GO:0031047 4 0.011
Worm
phagocytosis engulfment GO:0006911 1 0.011
response to topologically incorrect protein GO:0035966 2 0.011
positive regulation of jnk cascade GO:0046330 3 0.011
negative regulation of cell cycle phase transition GO:1901988 5 0.011
proteasomal protein catabolic process GO:0010498 2 0.011
negative regulation of innate immune response GO:0045824 2 0.011
cellular component morphogenesis GO:0032989 336 0.011
regulation of anatomical structure morphogenesis GO:0022603 130 0.011
establishment of monopolar cell polarity GO:0061162 2 0.011
regulation of cellular protein metabolic process GO:0032268 52 0.011
Human
nucleoside monophosphate catabolic process GO:0009125 4 0.011
Human
embryonic skeletal system development GO:0048706 97 0.011
regulation of protein polymerization GO:0032271 2 0.011
regulation of organelle assembly GO:1902115 4 0.011
regulation of establishment or maintenance of cell polarity GO:0032878 2 0.011
lipid catabolic process GO:0016042 4 0.011
regulation of translational initiation GO:0006446 1 0.011
embryonic skeletal joint morphogenesis GO:0060272 3 0.011
negative regulation of ras protein signal transduction GO:0046580 1 0.011
hormone secretion GO:0046879 2 0.011
blood vessel development GO:0001568 246 0.011
central nervous system development GO:0007417 387 0.011
brain development GO:0007420 293 0.011
positive regulation of programmed cell death GO:0043068 29 0.011
endoderm development GO:0007492 49 0.011
cell projection organization GO:0030030 284 0.011
gastrulation GO:0007369 208 0.011
guanosine containing compound catabolic process GO:1901069 2 0.011
notch signaling pathway GO:0007219 35 0.011
regulation of programmed cell death GO:0043067 101 0.011
regulation of cell differentiation GO:0045595 142 0.011
sensory organ morphogenesis GO:0090596 200 0.011
response to hormone GO:0009725 48 0.011
negative regulation of multi organism process GO:0043901 3 0.011
protein heterooligomerization GO:0051291 1 0.011
neuroblast differentiation GO:0014016 1 0.011
nuclear export GO:0051168 1 0.010
mesenchymal cell differentiation GO:0048762 87 0.010
heart morphogenesis GO:0003007 156 0.010
cell fate commitment GO:0045165 99 0.010
ovulation cycle GO:0042698 2 0.010
establishment of spindle orientation GO:0051294 10 0.010
organophosphate metabolic process GO:0019637 37 0.010
Human
non canonical wnt signaling pathway GO:0035567 13 0.010
negative regulation of multicellular organismal process GO:0051241 69 0.010
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.010
type i interferon production GO:0032606 2 0.010
regulation of synaptic plasticity GO:0048167 1 0.010
protein localization to plasma membrane GO:0072659 1 0.010
exocrine system development GO:0035272 28 0.010
protein complex subunit organization GO:0071822 46 0.010
Human
regulation of phosphate metabolic process GO:0019220 43 0.010
mrna 3 end processing GO:0031124 2 0.010
regulation of wnt signaling pathway GO:0030111 53 0.010
negative regulation of mapk cascade GO:0043409 4 0.010
negative regulation of chromatin modification GO:1903309 1 0.010
sequestering of metal ion GO:0051238 3 0.010
entrainment of circadian clock by photoperiod GO:0043153 1 0.010

upf1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
disease of metabolism DOID:0014667 0 0.010