Danio rerio

0 known processes

usp1

ubiquitin specific protease 1

(Aliases: zgc:55962,wu:fb43a02)

usp1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.285
dna methylation GO:0006306 8 0.212
positive regulation of chromatin modification GO:1903310 1 0.199
organic cyclic compound metabolic process GO:1901360 301 0.193
Human
aging GO:0007568 2 0.176
amine metabolic process GO:0009308 2 0.164
regulation of cellular amine metabolic process GO:0033238 0 0.161
signal transduction GO:0007165 455 0.153
macromolecule methylation GO:0043414 19 0.151
histone h4 k20 methylation GO:0034770 2 0.148
cellular amine metabolic process GO:0044106 2 0.137
protein acetylation GO:0006473 2 0.136
cellular nitrogen compound metabolic process GO:0034641 290 0.135
Human
negative regulation of biological process GO:0048519 304 0.129
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.124
histone h3 k9 modification GO:0061647 5 0.123
internal protein amino acid acetylation GO:0006475 2 0.108
immune system development GO:0002520 191 0.106
cellular aromatic compound metabolic process GO:0006725 295 0.099
Human
spliceosomal snrnp assembly GO:0000387 2 0.098
macromolecular complex subunit organization GO:0043933 74 0.097
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.090
stem cell maintenance GO:0019827 4 0.085
nucleobase containing compound metabolic process GO:0006139 274 0.085
Human
regulation of multicellular organism growth GO:0040014 4 0.085
dna modification GO:0006304 8 0.082
heterocycle metabolic process GO:0046483 290 0.080
Human
internal peptidyl lysine acetylation GO:0018393 2 0.077
meiotic nuclear division GO:0007126 4 0.076
multicellular organism growth GO:0035264 4 0.076
positive regulation of cellular amine metabolic process GO:0033240 0 0.075
cellular component morphogenesis GO:0032989 336 0.075
positive regulation of dna metabolic process GO:0051054 1 0.072
regulation of cellular metabolic process GO:0031323 320 0.070
Human
hematopoietic or lymphoid organ development GO:0048534 191 0.070
regulation of metabolic process GO:0019222 359 0.067
Human
negative regulation of dna metabolic process GO:0051053 4 0.067
peptidyl lysine dimethylation GO:0018027 1 0.065
cell morphogenesis GO:0000902 289 0.065
nucleic acid templated transcription GO:0097659 181 0.063
response to organic substance GO:0010033 153 0.063
rna biosynthetic process GO:0032774 181 0.063
positive regulation of macromolecule metabolic process GO:0010604 93 0.062
small gtpase mediated signal transduction GO:0007264 8 0.061
heterocycle biosynthetic process GO:0018130 215 0.060
nitrogen compound metabolic process GO:0006807 319 0.059
Human
immune system process GO:0002376 241 0.059
nucleic acid metabolic process GO:0090304 244 0.058
Human
positive regulation of cellular process GO:0048522 201 0.057
single organism metabolic process GO:0044710 217 0.056
Human
peptidyl lysine acetylation GO:0018394 2 0.055
regulation of signal transduction GO:0009966 225 0.055
mitotic dna integrity checkpoint GO:0044774 4 0.055
response to chemical GO:0042221 320 0.055
peptidyl lysine trimethylation GO:0018023 1 0.054
positive regulation of histone modification GO:0031058 1 0.053
mitotic g2 dna damage checkpoint GO:0007095 3 0.052
organic cyclic compound biosynthetic process GO:1901362 223 0.052
nuclear pore organization GO:0006999 2 0.051
organic substance biosynthetic process GO:1901576 289 0.051
regulation of primary metabolic process GO:0080090 311 0.051
Human
oxoacid metabolic process GO:0043436 31 0.051
negative regulation of ras protein signal transduction GO:0046580 1 0.051
cytokinesis GO:0000910 3 0.050
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.050
regulation of gene silencing GO:0060968 1 0.050
small molecule metabolic process GO:0044281 77 0.050
regulation of cell activation GO:0050865 1 0.048
positive regulation of chromosome organization GO:2001252 1 0.048
histone methylation GO:0016571 13 0.048
peptidyl lysine methylation GO:0018022 3 0.047
cellular ketone metabolic process GO:0042180 11 0.047
cellular nitrogen compound biosynthetic process GO:0044271 218 0.047
intracellular signal transduction GO:0035556 85 0.047
digestive system development GO:0055123 289 0.046
cell aging GO:0007569 2 0.046
transcription from rna polymerase ii promoter GO:0006366 80 0.046
regulation of response to stimulus GO:0048583 269 0.045
Human
dna alkylation GO:0006305 8 0.045
cognition GO:0050890 1 0.045
organonitrogen compound metabolic process GO:1901564 74 0.045
covalent chromatin modification GO:0016569 20 0.045
negative regulation of rna metabolic process GO:0051253 48 0.044
positive regulation of biological process GO:0048518 253 0.044
regulation of cellular ketone metabolic process GO:0010565 7 0.044
regulation of biological quality GO:0065008 263 0.044
meiotic cell cycle process GO:1903046 3 0.044
negative regulation of gene expression GO:0010629 65 0.043
cellular component biogenesis GO:0044085 178 0.043
negative regulation of cellular process GO:0048523 283 0.042
regulation of macromolecule biosynthetic process GO:0010556 225 0.042
mitotic g2 m transition checkpoint GO:0044818 3 0.042
regulation of signaling GO:0023051 235 0.042
transcription dna templated GO:0006351 181 0.042
regulation of establishment of protein localization GO:0070201 4 0.041
regulation of cellular amino acid metabolic process GO:0006521 0 0.041
regulation of gene expression epigenetic GO:0040029 11 0.041
positive regulation of cell activation GO:0050867 1 0.041
positive regulation of biosynthetic process GO:0009891 68 0.040
organic acid metabolic process GO:0006082 31 0.040
regulation of nitrogen compound metabolic process GO:0051171 251 0.038
Human
b cell activation GO:0042113 2 0.038
nucleobase containing compound biosynthetic process GO:0034654 205 0.038
positive regulation of cellular component biogenesis GO:0044089 3 0.038
negative regulation of cell differentiation GO:0045596 46 0.038
negative regulation of signal transduction GO:0009968 94 0.038
regulation of biosynthetic process GO:0009889 250 0.038
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.038
aromatic compound biosynthetic process GO:0019438 217 0.037
negative regulation of cell communication GO:0010648 96 0.037
chromatin modification GO:0016568 21 0.037
cell motility GO:0048870 244 0.036
cellular macromolecule biosynthetic process GO:0034645 224 0.036
regulation of histone h3 k9 methylation GO:0051570 2 0.036
regulation of cellular component organization GO:0051128 86 0.036
protein methylation GO:0006479 13 0.035
protein acylation GO:0043543 3 0.034
ras protein signal transduction GO:0007265 7 0.034
immunoglobulin mediated immune response GO:0016064 3 0.033
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.033
carboxylic acid metabolic process GO:0019752 22 0.033
regulation of dna replication GO:0006275 3 0.033
protein alkylation GO:0008213 13 0.032
cellular amino acid metabolic process GO:0006520 7 0.032
lipid storage GO:0019915 1 0.032
head development GO:0060322 303 0.032
protein localization to nucleus GO:0034504 3 0.031
negative regulation of chromatin modification GO:1903309 1 0.031
central nervous system development GO:0007417 387 0.031
protein complex localization GO:0031503 1 0.031
gene expression GO:0010467 252 0.031
regionalization GO:0003002 274 0.030
growth GO:0040007 174 0.030
homeostatic process GO:0042592 142 0.030
biosynthetic process GO:0009058 294 0.030
regulation of cell communication GO:0010646 232 0.029
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.029
regulation of nucleic acid templated transcription GO:1903506 213 0.029
developmental growth GO:0048589 166 0.029
leukocyte proliferation GO:0070661 1 0.029
nuclear pore complex assembly GO:0051292 2 0.029
chemosensory behavior GO:0007635 1 0.029
chromosome organization GO:0051276 31 0.029
negative regulation of rna biosynthetic process GO:1902679 45 0.028
regulation of rna metabolic process GO:0051252 224 0.028
regulation of protein complex assembly GO:0043254 3 0.028
regulation of cellular biosynthetic process GO:0031326 245 0.028
protein modification process GO:0036211 100 0.027
Human
double strand break repair GO:0006302 3 0.027
dna methylation or demethylation GO:0044728 8 0.027
macromolecule modification GO:0043412 111 0.027
Human
cell proliferation GO:0008283 80 0.026
regulation of dna recombination GO:0000018 2 0.026
negative regulation of response to stimulus GO:0048585 104 0.026
cellular response to external stimulus GO:0071496 2 0.026
hemopoiesis GO:0030097 183 0.026
regulation of developmental process GO:0050793 247 0.026
negative regulation of cellular biosynthetic process GO:0031327 55 0.025
regulation of histone methylation GO:0031060 3 0.025
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.024
Human
regulation of protein transport GO:0051223 3 0.024
negative regulation of metabolic process GO:0009892 86 0.024
histone h3 k4 methylation GO:0051568 2 0.024
b cell mediated immunity GO:0019724 3 0.024
rna transport GO:0050658 2 0.024
dna biosynthetic process GO:0071897 3 0.023
single organism organelle organization GO:1902589 199 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.023
histone h3 k9 methylation GO:0051567 5 0.023
production of molecular mediator of immune response GO:0002440 2 0.023
regulation of production of molecular mediator of immune response GO:0002700 1 0.023
lateral inhibition GO:0046331 1 0.023
negative regulation of developmental process GO:0051093 65 0.023
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.023
meiosis i GO:0007127 1 0.023
rna localization GO:0006403 4 0.023
regulation of dna methylation GO:0044030 5 0.023
stem cell proliferation GO:0072089 4 0.022
segmentation GO:0035282 97 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.022
nucleocytoplasmic transport GO:0006913 4 0.022
embryo development ending in birth or egg hatching GO:0009792 271 0.021
rna metabolic process GO:0016070 219 0.021
protein metabolic process GO:0019538 183 0.021
Human
response to stress GO:0006950 263 0.021
Human
telomere maintenance GO:0000723 1 0.021
regulation of cell differentiation GO:0045595 142 0.021
regulation of chromatin organization GO:1902275 5 0.021
g2 dna damage checkpoint GO:0031572 3 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.020
mrna transport GO:0051028 2 0.020
apoptotic process GO:0006915 116 0.020
regulation of rna biosynthetic process GO:2001141 213 0.020
negative regulation of macromolecule metabolic process GO:0010605 76 0.020
gene silencing GO:0016458 4 0.020
cell cycle process GO:0022402 53 0.020
positive regulation of cellular metabolic process GO:0031325 94 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.019
protein targeting to nucleus GO:0044744 3 0.019
cellular component assembly involved in morphogenesis GO:0010927 107 0.019
cell cycle g2 m phase transition GO:0044839 4 0.019
regulation of reactive oxygen species metabolic process GO:2000377 2 0.019
cellular component disassembly GO:0022411 1 0.019
response to uv GO:0009411 3 0.019
Human
cytoskeleton organization GO:0007010 96 0.018
lymphocyte proliferation GO:0046651 1 0.018
positive regulation of metabolic process GO:0009893 108 0.018
mononuclear cell proliferation GO:0032943 1 0.018
cellular protein modification process GO:0006464 100 0.018
Human
double strand break repair via nonhomologous end joining GO:0006303 1 0.018
stem cell differentiation GO:0048863 117 0.018
rna 3 end processing GO:0031123 2 0.018
histone h3 k36 methylation GO:0010452 2 0.018
non recombinational repair GO:0000726 2 0.018
regulation of apoptotic process GO:0042981 98 0.018
localization within membrane GO:0051668 1 0.018
organelle organization GO:0006996 227 0.017
methylation GO:0032259 22 0.017
cellular response to chemical stimulus GO:0070887 157 0.017
regulation of gene expression GO:0010468 265 0.017
cellular macromolecular complex assembly GO:0034622 24 0.017
positive regulation of multicellular organismal process GO:0051240 52 0.017
reciprocal meiotic recombination GO:0007131 1 0.017
brain development GO:0007420 293 0.017
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.017
maintenance of location GO:0051235 4 0.017
g2 m transition of mitotic cell cycle GO:0000086 4 0.017
cellular component assembly GO:0022607 170 0.017
regulation of programmed cell death GO:0043067 101 0.016
centrosome organization GO:0051297 1 0.016
g1 s transition of mitotic cell cycle GO:0000082 1 0.016
nuclear migration GO:0007097 3 0.016
cellular localization GO:0051641 97 0.016
chromosome segregation GO:0007059 12 0.016
hematopoietic stem cell migration GO:0035701 4 0.016
mrna 3 end processing GO:0031124 2 0.016
nucleic acid transport GO:0050657 2 0.016
regulation of protein metabolic process GO:0051246 56 0.016
regulation of macromolecule metabolic process GO:0060255 317 0.015
Human
telomere organization GO:0032200 1 0.015
negative regulation of transcription dna templated GO:0045892 45 0.015
stem cell division GO:0017145 1 0.015
histone modification GO:0016570 20 0.015
digestive tract development GO:0048565 265 0.015
cellular biosynthetic process GO:0044249 286 0.015
cell part morphogenesis GO:0032990 246 0.015
localization of cell GO:0051674 244 0.015
cellular component movement GO:0006928 335 0.015
negative regulation of intracellular signal transduction GO:1902532 22 0.015
establishment of localization GO:0051234 244 0.014
cell migration GO:0016477 237 0.014
regulation of transcription dna templated GO:0006355 213 0.014
mitotic recombination GO:0006312 2 0.014
cell cycle GO:0007049 93 0.014
negative regulation of biosynthetic process GO:0009890 55 0.014
nuclear transport GO:0051169 4 0.014
positive regulation of rna metabolic process GO:0051254 59 0.014
cell cycle arrest GO:0007050 1 0.014
negative regulation of cell cycle process GO:0010948 9 0.014
nuclear export GO:0051168 1 0.014
digestive tract morphogenesis GO:0048546 231 0.014
protein import GO:0017038 3 0.014
intra s dna damage checkpoint GO:0031573 1 0.014
regulation of protein targeting GO:1903533 2 0.014
cellular response to stress GO:0033554 62 0.014
Human
protein complex disassembly GO:0043241 1 0.014
response to amino acid GO:0043200 2 0.014
chordate embryonic development GO:0043009 271 0.014
regulation of growth rate GO:0040009 1 0.014
cellular response to extracellular stimulus GO:0031668 2 0.013
reciprocal dna recombination GO:0035825 1 0.013
tube morphogenesis GO:0035239 349 0.013
meiotic chromosome segregation GO:0045132 3 0.013
positive regulation of transport GO:0051050 2 0.013
macromolecular complex disassembly GO:0032984 1 0.013
somatic cell dna recombination GO:0016444 1 0.013
locomotion GO:0040011 313 0.013
generation of neurons GO:0048699 385 0.013
positive regulation of cellular biosynthetic process GO:0031328 68 0.013
microtubule organizing center organization GO:0031023 1 0.013
regulation of stem cell differentiation GO:2000736 4 0.013
chromatin organization GO:0006325 22 0.013
cardiac atrium morphogenesis GO:0003209 2 0.013
establishment of rna localization GO:0051236 3 0.012
regulation of meiotic cell cycle GO:0051445 1 0.012
homeostasis of number of cells GO:0048872 62 0.012
rna processing GO:0006396 25 0.012
regulation of growth GO:0040008 42 0.012
autophagy GO:0006914 4 0.012
regulation of cellular protein metabolic process GO:0032268 52 0.012
synaptic vesicle transport GO:0048489 1 0.012
negative regulation of dna replication GO:0008156 2 0.012
spindle assembly GO:0051225 2 0.012
gastrulation GO:0007369 208 0.012
regulation of protein localization to nucleus GO:1900180 2 0.012
cellular response to dna damage stimulus GO:0006974 24 0.012
Human
positive regulation of cellular catabolic process GO:0031331 3 0.012
regulation of dna metabolic process GO:0051052 11 0.011
Human
negative regulation of protein phosphorylation GO:0001933 4 0.011
programmed cell death GO:0012501 119 0.011
positive regulation of rna biosynthetic process GO:1902680 57 0.011
dorsal ventral pattern formation GO:0009953 125 0.011
mitotic dna damage checkpoint GO:0044773 4 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.011
death GO:0016265 121 0.011
regulation of chromatin modification GO:1903308 5 0.011
purine nucleoside monophosphate catabolic process GO:0009128 4 0.011
ncrna catabolic process GO:0034661 1 0.011
regulation of dna templated transcription elongation GO:0032784 3 0.011
neurological system process GO:0050877 62 0.011
somitogenesis GO:0001756 87 0.011
regulation of skeletal muscle tissue development GO:0048641 4 0.011
negative regulation of cellular metabolic process GO:0031324 77 0.011
negative regulation of mapk cascade GO:0043409 4 0.011
positive regulation of immune effector process GO:0002699 3 0.011
single organism nuclear import GO:1902593 3 0.011
cellular protein complex localization GO:0034629 1 0.011
regulation of developmental growth GO:0048638 38 0.011
immunoglobulin production GO:0002377 1 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.011
regulation of histone modification GO:0031056 5 0.011
protein polymerization GO:0051258 4 0.010
embryonic organ development GO:0048568 381 0.010
macromolecule biosynthetic process GO:0009059 227 0.010
cell fate commitment GO:0045165 99 0.010
negative regulation of intracellular transport GO:0032387 3 0.010
regulation of intracellular protein transport GO:0033157 3 0.010
dna templated transcription elongation GO:0006354 3 0.010
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.010
regulation of stem cell proliferation GO:0072091 2 0.010
pore complex assembly GO:0046931 2 0.010
system process GO:0003008 185 0.010
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.010
nucleobase containing compound transport GO:0015931 2 0.010
embryonic skeletal system development GO:0048706 97 0.010

usp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.070
nervous system disease DOID:863 0 0.070
sensory system disease DOID:0050155 0 0.013