Danio rerio

23 known processes

uspl1

ubiquitin specific peptidase like 1

(Aliases: c13orf22l,MGC174731)

uspl1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.271
protein localization to nucleus GO:0034504 3 0.185
gene expression GO:0010467 252 0.162
cellular nitrogen compound biosynthetic process GO:0044271 218 0.131
rna biosynthetic process GO:0032774 181 0.122
regulation of intracellular protein transport GO:0033157 3 0.114
regulation of protein localization to nucleus GO:1900180 2 0.111
heterocycle biosynthetic process GO:0018130 215 0.108
rna metabolic process GO:0016070 219 0.107
regulation of establishment of protein localization GO:0070201 4 0.105
organic substance biosynthetic process GO:1901576 289 0.105
aging GO:0007568 2 0.102
regulation of protein transport GO:0051223 3 0.100
regulation of cellular metabolic process GO:0031323 320 0.096
nuclear transport GO:0051169 4 0.093
negative regulation of protein transport GO:0051224 3 0.088
aromatic compound biosynthetic process GO:0019438 217 0.088
nucleocytoplasmic transport GO:0006913 4 0.087
biosynthetic process GO:0009058 294 0.085
organic cyclic compound biosynthetic process GO:1901362 223 0.084
digestive tract development GO:0048565 265 0.084
cellular macromolecule biosynthetic process GO:0034645 224 0.083
regulation of transcription dna templated GO:0006355 213 0.081
regulation of protein import into nucleus GO:0042306 2 0.079
cellular macromolecule metabolic process GO:0044260 391 0.076
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.074
transcription dna templated GO:0006351 181 0.073
regulation of biosynthetic process GO:0009889 250 0.069
organic cyclic compound metabolic process GO:1901360 301 0.069
locomotion GO:0040011 313 0.068
nucleobase containing compound biosynthetic process GO:0034654 205 0.067
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.066
neuron differentiation GO:0030182 353 0.065
macromolecule biosynthetic process GO:0009059 227 0.064
cellular biosynthetic process GO:0044249 286 0.064
heterocycle metabolic process GO:0046483 290 0.063
regulation of developmental process GO:0050793 247 0.063
cellular aromatic compound metabolic process GO:0006725 295 0.059
regulation of protein targeting GO:1903533 2 0.058
multicellular organism growth GO:0035264 4 0.058
protein import into nucleus GO:0006606 3 0.057
regulation of rna metabolic process GO:0051252 224 0.055
cognition GO:0050890 1 0.054
regulation of multicellular organism growth GO:0040014 4 0.054
regulation of metabolic process GO:0019222 359 0.053
cellular component morphogenesis GO:0032989 336 0.052
regulation of cellular biosynthetic process GO:0031326 245 0.051
peptidyl lysine acetylation GO:0018394 2 0.051
regulation of cytoplasmic transport GO:1903649 4 0.050
positive regulation of transport GO:0051050 2 0.049
single organism metabolic process GO:0044710 217 0.048
nucleic acid metabolic process GO:0090304 244 0.047
nitrogen compound metabolic process GO:0006807 319 0.047
internal peptidyl lysine acetylation GO:0018393 2 0.047
generation of neurons GO:0048699 385 0.046
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.045
nuclear import GO:0051170 3 0.045
regulation of nucleic acid templated transcription GO:1903506 213 0.045
neuron development GO:0048666 262 0.043
nuclear export GO:0051168 1 0.042
regulation of macromolecule metabolic process GO:0060255 317 0.041
cell cycle g1 s phase transition GO:0044843 1 0.041
amine metabolic process GO:0009308 2 0.041
negative regulation of intracellular protein transport GO:0090317 3 0.041
establishment of protein localization to organelle GO:0072594 4 0.041
locomotor rhythm GO:0045475 3 0.040
positive regulation of cellular process GO:0048522 201 0.040
response to stress GO:0006950 263 0.040
protein import GO:0017038 3 0.040
maintenance of location GO:0051235 4 0.039
establishment of localization GO:0051234 244 0.038
regulation of cell shape GO:0008360 1 0.038
cellular amine metabolic process GO:0044106 2 0.038
system process GO:0003008 185 0.037
nucleic acid templated transcription GO:0097659 181 0.037
regulation of macromolecule biosynthetic process GO:0010556 225 0.037
nucleic acid transport GO:0050657 2 0.036
single organism localization GO:1902578 225 0.036
cytokinesis GO:0000910 3 0.036
g1 s transition of mitotic cell cycle GO:0000082 1 0.036
regulation of nitrogen compound metabolic process GO:0051171 251 0.036
positive regulation of cellular biosynthetic process GO:0031328 68 0.035
cellular ketone metabolic process GO:0042180 11 0.035
internal protein amino acid acetylation GO:0006475 2 0.035
protein acetylation GO:0006473 2 0.035
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.035
negative regulation of protein import into nucleus GO:0042308 2 0.034
eye development GO:0001654 277 0.034
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.034
regulation of gene expression GO:0010468 265 0.034
cell projection organization GO:0030030 284 0.034
negative regulation of protein localization to nucleus GO:1900181 2 0.033
cellular nitrogen compound metabolic process GO:0034641 290 0.033
transport GO:0006810 220 0.033
autophagy GO:0006914 4 0.032
protein acylation GO:0043543 3 0.032
nucleobase containing compound metabolic process GO:0006139 274 0.031
rna transport GO:0050658 2 0.031
digestive system development GO:0055123 289 0.031
spindle assembly GO:0051225 2 0.030
skin development GO:0043588 54 0.030
apoptotic process GO:0006915 116 0.030
regulation of response to stimulus GO:0048583 269 0.029
negative regulation of intracellular transport GO:0032387 3 0.028
positive regulation of rna metabolic process GO:0051254 59 0.028
positive regulation of biosynthetic process GO:0009891 68 0.028
regulation of cellular amino acid metabolic process GO:0006521 0 0.028
regulation of rna biosynthetic process GO:2001141 213 0.028
localization of cell GO:0051674 244 0.027
regulation of cellular ketone metabolic process GO:0010565 7 0.027
modification dependent macromolecule catabolic process GO:0043632 3 0.027
regulation of erk1 and erk2 cascade GO:0070372 4 0.027
cellular component disassembly GO:0022411 1 0.027
response to nutrient GO:0007584 3 0.026
transcription from rna polymerase ii promoter GO:0006366 80 0.026
negative regulation of ras protein signal transduction GO:0046580 1 0.025
vasculature development GO:0001944 278 0.025
organonitrogen compound metabolic process GO:1901564 74 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.025
centrosome duplication GO:0051298 1 0.025
regulation of biological quality GO:0065008 263 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.024
embryo development ending in birth or egg hatching GO:0009792 271 0.024
signal transduction by p53 class mediator GO:0072331 13 0.024
regulation of dna templated transcription elongation GO:0032784 3 0.024
cell migration GO:0016477 237 0.024
rna localization GO:0006403 4 0.024
positive regulation of rna biosynthetic process GO:1902680 57 0.023
cellular response to external stimulus GO:0071496 2 0.023
regulation of primary metabolic process GO:0080090 311 0.023
protein complex disassembly GO:0043241 1 0.023
macromolecular complex disassembly GO:0032984 1 0.023
production of molecular mediator of immune response GO:0002440 2 0.023
cellular component movement GO:0006928 335 0.023
neuron projection development GO:0031175 180 0.023
carboxylic acid metabolic process GO:0019752 22 0.023
response to carbohydrate GO:0009743 3 0.023
positive regulation of cell activation GO:0050867 1 0.023
single organism transport GO:0044765 206 0.023
positive regulation of macromolecule metabolic process GO:0010604 93 0.023
positive regulation of cell cycle GO:0045787 3 0.022
lipid storage GO:0019915 1 0.022
positive regulation of dna metabolic process GO:0051054 1 0.022
regulation of multicellular organismal development GO:2000026 223 0.022
erk1 and erk2 cascade GO:0070371 4 0.022
regulation of signaling GO:0023051 235 0.021
immune system process GO:0002376 241 0.021
rna export from nucleus GO:0006405 1 0.021
chromatin modification GO:0016568 21 0.021
regulation of cellular amine metabolic process GO:0033238 0 0.021
b cell activation GO:0042113 2 0.021
cellular protein catabolic process GO:0044257 4 0.021
chemosensory behavior GO:0007635 1 0.021
small molecule metabolic process GO:0044281 77 0.021
immune system development GO:0002520 191 0.020
cell morphogenesis GO:0000902 289 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.020
positive regulation of cellular amine metabolic process GO:0033240 0 0.020
female sex differentiation GO:0046660 4 0.020
interspecies interaction between organisms GO:0044419 4 0.020
regulation of photoreceptor cell differentiation GO:0046532 2 0.020
regulation of cell activation GO:0050865 1 0.020
cell projection morphogenesis GO:0048858 244 0.020
neurological system process GO:0050877 62 0.019
cell death GO:0008219 121 0.019
retina development in camera type eye GO:0060041 146 0.019
regulation of apoptotic process GO:0042981 98 0.019
regulation of protein complex assembly GO:0043254 3 0.019
establishment of rna localization GO:0051236 3 0.019
hemopoiesis GO:0030097 183 0.019
histone h3 k4 methylation GO:0051568 2 0.019
ameboidal type cell migration GO:0001667 143 0.019
cellular carbohydrate metabolic process GO:0044262 4 0.019
phagocytosis GO:0006909 3 0.019
positive regulation of transcription dna templated GO:0045893 57 0.019
viral process GO:0016032 1 0.019
regulation of multicellular organismal process GO:0051239 277 0.019
developmental pigmentation GO:0048066 48 0.018
cell part morphogenesis GO:0032990 246 0.018
signal transduction GO:0007165 455 0.018
regulation of signal transduction GO:0009966 225 0.018
ras protein signal transduction GO:0007265 7 0.018
dna templated transcription elongation GO:0006354 3 0.018
blood vessel development GO:0001568 246 0.018
ribonucleoside monophosphate catabolic process GO:0009158 4 0.018
cell motility GO:0048870 244 0.018
positive regulation of cellular component biogenesis GO:0044089 3 0.018
positive regulation of leukocyte differentiation GO:1902107 1 0.018
cellular response to extracellular stimulus GO:0031668 2 0.018
polarized epithelial cell differentiation GO:0030859 4 0.018
nucleoside monophosphate catabolic process GO:0009125 4 0.017
cell morphogenesis involved in differentiation GO:0000904 195 0.017
positive regulation of chromatin modification GO:1903310 1 0.017
cytoskeleton dependent cytokinesis GO:0061640 3 0.017
taxis GO:0042330 109 0.017
protein targeting to nucleus GO:0044744 3 0.017
regulation of embryonic development GO:0045995 47 0.017
negative regulation of biological process GO:0048519 304 0.017
ubiquitin dependent protein catabolic process GO:0006511 3 0.017
regulation of cell differentiation GO:0045595 142 0.017
positive regulation of histone modification GO:0031058 1 0.017
regulation of cell communication GO:0010646 232 0.017
cellular protein modification process GO:0006464 100 0.017
negative regulation of developmental process GO:0051093 65 0.017
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.017
regulation of production of molecular mediator of immune response GO:0002700 1 0.016
response to alkaloid GO:0043279 2 0.016
positive regulation of immune effector process GO:0002699 3 0.016
atp catabolic process GO:0006200 4 0.016
membrane lipid biosynthetic process GO:0046467 2 0.016
regulation of chromosome segregation GO:0051983 1 0.016
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.016
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.016
negative regulation of cellular process GO:0048523 283 0.016
cellular response to nutrient levels GO:0031669 2 0.016
dna templated transcription initiation GO:0006352 1 0.016
hematopoietic or lymphoid organ development GO:0048534 191 0.016
female gonad development GO:0008585 4 0.016
regulation of stem cell proliferation GO:0072091 2 0.016
positive regulation of chromosome organization GO:2001252 1 0.016
regulation of cell development GO:0060284 100 0.016
protein localization to plasma membrane GO:0072659 1 0.016
meiotic chromosome segregation GO:0045132 3 0.016
development of primary female sexual characteristics GO:0046545 4 0.016
regulation of localization GO:0032879 104 0.016
programmed cell death GO:0012501 119 0.016
regulation of anatomical structure morphogenesis GO:0022603 130 0.016
small gtpase mediated signal transduction GO:0007264 8 0.015
stem cell proliferation GO:0072089 4 0.015
oxoacid metabolic process GO:0043436 31 0.015
hormone transport GO:0009914 2 0.015
g2 dna damage checkpoint GO:0031572 3 0.015
positive regulation of myeloid cell differentiation GO:0045639 2 0.015
regulation of cell death GO:0010941 103 0.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.015
i kappab kinase nf kappab signaling GO:0007249 4 0.015
modification dependent protein catabolic process GO:0019941 3 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.015
mesoderm development GO:0007498 88 0.015
positive regulation of metabolic process GO:0009893 108 0.015
cell adhesion GO:0007155 40 0.015
sensory organ development GO:0007423 393 0.015
regulation of meiotic cell cycle GO:0051445 1 0.015
response to drug GO:0042493 3 0.015
positive regulation of muscle tissue development GO:1901863 1 0.014
response to ketone GO:1901654 1 0.014
neuroblast proliferation GO:0007405 2 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.014
meiotic cell cycle process GO:1903046 3 0.014
cellular amino acid metabolic process GO:0006520 7 0.014
stem cell division GO:0017145 1 0.014
positive regulation of leukocyte mediated immunity GO:0002705 1 0.014
death GO:0016265 121 0.014
negative regulation of protein phosphorylation GO:0001933 4 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.014
leukocyte proliferation GO:0070661 1 0.014
organic acid metabolic process GO:0006082 31 0.014
response to hexose GO:0009746 3 0.014
regulation of binding GO:0051098 3 0.014
stem cell maintenance GO:0019827 4 0.014
lymphocyte proliferation GO:0046651 1 0.014
regulation of cellular component organization GO:0051128 86 0.014
multi organism process GO:0051704 134 0.014
proteasomal protein catabolic process GO:0010498 2 0.014
regulation of organelle assembly GO:1902115 4 0.014
camera type eye development GO:0043010 222 0.014
myeloid cell homeostasis GO:0002262 56 0.013
positive regulation of protein complex assembly GO:0031334 2 0.013
neuron projection morphogenesis GO:0048812 161 0.013
rna 3 end processing GO:0031123 2 0.013
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.013
homeostatic process GO:0042592 142 0.013
phosphorus metabolic process GO:0006793 109 0.013
phosphate containing compound metabolic process GO:0006796 108 0.013
myeloid cell differentiation GO:0030099 86 0.013
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.013
tube morphogenesis GO:0035239 349 0.013
positive regulation of nucleic acid templated transcription GO:1903508 57 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
positive regulation of striated muscle tissue development GO:0045844 1 0.013
negative regulation of cytoplasmic transport GO:1903650 2 0.013
meiotic nuclear division GO:0007126 4 0.013
centrosome organization GO:0051297 1 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.013
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.013
angiogenesis GO:0001525 158 0.013
regulation of hormone secretion GO:0046883 2 0.013
protein modification process GO:0036211 100 0.013
cellular response to biotic stimulus GO:0071216 3 0.013
regulation of cytokine production GO:0001817 3 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.013
response to organic substance GO:0010033 153 0.013
positive regulation of secretion GO:0051047 1 0.013
peptidyl serine modification GO:0018209 2 0.013
regulation of reactive oxygen species metabolic process GO:2000377 2 0.013
cell matrix adhesion GO:0007160 4 0.012
protein polymerization GO:0051258 4 0.012
glucose homeostasis GO:0042593 1 0.012
eye morphogenesis GO:0048592 144 0.012
carbohydrate homeostasis GO:0033500 1 0.012
axon guidance GO:0007411 86 0.012
developmental programmed cell death GO:0010623 4 0.012
axonogenesis GO:0007409 152 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
regulation of histone methylation GO:0031060 3 0.012
cellular response to starvation GO:0009267 1 0.012
pigmentation GO:0043473 85 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.012
regulation of synapse organization GO:0050807 3 0.012
membrane invagination GO:0010324 1 0.012
extrinsic apoptotic signaling pathway GO:0097191 3 0.012
nucleobase containing compound transport GO:0015931 2 0.012
chromatin organization GO:0006325 22 0.012
cellular response to radiation GO:0071478 4 0.012
ovulation cycle GO:0042698 2 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.012
negative regulation of gliogenesis GO:0014014 1 0.012
peptidyl threonine phosphorylation GO:0018107 1 0.012
adult behavior GO:0030534 2 0.012
regulation of nervous system development GO:0051960 90 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.012
regulation of organ growth GO:0046620 3 0.012
stem cell differentiation GO:0048863 117 0.011
cellular response to stress GO:0033554 62 0.011
embryonic organ development GO:0048568 381 0.011
peptidyl serine phosphorylation GO:0018105 1 0.011
hormone secretion GO:0046879 2 0.011
regulation of synapse assembly GO:0051963 3 0.011
establishment of localization in cell GO:0051649 77 0.011
positive regulation of multi organism process GO:0043902 3 0.011
cell surface receptor signaling pathway GO:0007166 325 0.011
response to monosaccharide GO:0034284 3 0.011
negative regulation of cytokine production GO:0001818 1 0.011
regulation of blood pressure GO:0008217 1 0.011
positive regulation of cellular catabolic process GO:0031331 3 0.011
single organism organelle organization GO:1902589 199 0.011
negative regulation of epithelial cell proliferation GO:0050680 1 0.011
muscle structure development GO:0061061 196 0.011
peptide transport GO:0015833 1 0.011
regulation of programmed cell death GO:0043067 101 0.011
behavior GO:0007610 74 0.011
regulation of dna templated transcription in response to stress GO:0043620 0 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.011
sphingolipid biosynthetic process GO:0030148 2 0.011
somatic cell dna recombination GO:0016444 1 0.011
mononuclear cell proliferation GO:0032943 1 0.011
septum transversum development GO:0003343 4 0.011
organic substance transport GO:0071702 58 0.011
protein polyubiquitination GO:0000209 4 0.011
regulation of microtubule cytoskeleton organization GO:0070507 3 0.011
positive regulation of dna templated transcription elongation GO:0032786 1 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
cellular response to reactive oxygen species GO:0034614 2 0.011
positive regulation of catabolic process GO:0009896 4 0.011
cell migration involved in gastrulation GO:0042074 79 0.011
regulation of response to extracellular stimulus GO:0032104 1 0.010
mrna transport GO:0051028 2 0.010
mesenchymal cell development GO:0014031 78 0.010
recombinational repair GO:0000725 1 0.010
regulation of nucleocytoplasmic transport GO:0046822 2 0.010
developmental growth GO:0048589 166 0.010
muscle organ development GO:0007517 101 0.010
meiosis ii GO:0007135 1 0.010
b cell differentiation GO:0030183 1 0.010
ovulation cycle process GO:0022602 2 0.010
response to hydrogen peroxide GO:0042542 3 0.010
response to corticosteroid GO:0031960 1 0.010
macromolecular complex subunit organization GO:0043933 74 0.010
negative regulation of signal transduction GO:0009968 94 0.010
negative regulation of multi organism process GO:0043901 3 0.010
positive regulation of biological process GO:0048518 253 0.010
chemotaxis GO:0006935 104 0.010
response to glucose GO:0009749 3 0.010
negative regulation of dna metabolic process GO:0051053 4 0.010
spermatid differentiation GO:0048515 2 0.010
regulation of purine nucleotide catabolic process GO:0033121 2 0.010

uspl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.027
disease of anatomical entity DOID:7 0 0.027
disease of cellular proliferation DOID:14566 0 0.015
cancer DOID:162 0 0.010
organ system cancer DOID:0050686 0 0.010
retinal disease DOID:5679 0 0.010
eye and adnexa disease DOID:1492 0 0.010
sensory system disease DOID:0050155 0 0.010
eye disease DOID:5614 0 0.010