Danio rerio

74 known processes

vps18

vacuolar protein sorting protein 18

(Aliases: fj35h10,MGC103535,wu:fj35h10,chunp6929,MGC173734,hm:zehl0587)

vps18 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.575
embryo development ending in birth or egg hatching GO:0009792 271 0.277
regulation of cellular metabolic process GO:0031323 320 0.202
retina development in camera type eye GO:0060041 146 0.195
transition metal ion transport GO:0000041 6 0.185
eye development GO:0001654 277 0.178
response to transition metal nanoparticle GO:1990267 28 0.105
aging GO:0007568 2 0.095
Fly
camera type eye development GO:0043010 222 0.092
zinc ion transport GO:0006829 2 0.088
sensory organ development GO:0007423 393 0.080
autophagy GO:0006914 4 0.079
Fly
zinc ion homeostasis GO:0055069 1 0.072
maintenance of location GO:0051235 4 0.065
signal transduction GO:0007165 455 0.064
Fly
organelle organization GO:0006996 227 0.053
locomotion GO:0040011 313 0.053
Fly
establishment of localization GO:0051234 244 0.053
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.051
fertilization GO:0009566 3 0.051
i kappab kinase nf kappab signaling GO:0007249 4 0.047
embryonic organ development GO:0048568 381 0.047
vasculature development GO:0001944 278 0.046
endosome to lysosome transport GO:0008333 1 0.045
response to zinc ion GO:0010043 6 0.044
regulation of macromolecule metabolic process GO:0060255 317 0.044
endosomal transport GO:0016197 2 0.043
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.043
hemopoiesis GO:0030097 183 0.041
cellular transition metal ion homeostasis GO:0046916 3 0.041
spermatid development GO:0007286 2 0.040
regulation of epithelial cell proliferation GO:0050678 3 0.039
transport GO:0006810 220 0.039
lipid storage GO:0019915 1 0.037
lysosomal transport GO:0007041 2 0.037
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.035
regulation of cellular ketone metabolic process GO:0010565 7 0.035
regulation of metabolic process GO:0019222 359 0.034
notochord cell differentiation GO:0060034 18 0.033
regulation of protein ubiquitination GO:0031396 3 0.033
gene expression GO:0010467 252 0.032
regulation of autophagy GO:0010506 3 0.032
centrosome cycle GO:0007098 1 0.031
response to stress GO:0006950 263 0.030
Fly
multicellular organism growth GO:0035264 4 0.030
nucleic acid transport GO:0050657 2 0.029
sex determination GO:0007530 1 0.029
zinc ion transmembrane transport GO:0071577 1 0.028
sensory organ morphogenesis GO:0090596 200 0.028
synaptic vesicle transport GO:0048489 1 0.028
notochord cell development GO:0060035 9 0.028
regulation of signal transduction GO:0009966 225 0.027
Fly
protein metabolic process GO:0019538 183 0.027
Fly
alpha amino acid metabolic process GO:1901605 3 0.027
cognition GO:0050890 1 0.027
regulation of primary metabolic process GO:0080090 311 0.027
establishment of synaptic vesicle localization GO:0097480 1 0.027
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.027
cellular carbohydrate metabolic process GO:0044262 4 0.026
phagocytosis GO:0006909 3 0.026
Worm
multi organism process GO:0051704 134 0.026
Fly
positive regulation of biological process GO:0048518 253 0.026
phagocytosis engulfment GO:0006911 1 0.025
regulation of developmental process GO:0050793 247 0.024
single fertilization GO:0007338 3 0.024
meiotic cell cycle process GO:1903046 3 0.024
locomotor rhythm GO:0045475 3 0.024
eye morphogenesis GO:0048592 144 0.024
cellular ketone metabolic process GO:0042180 11 0.024
immune system development GO:0002520 191 0.024
microtubule organizing center organization GO:0031023 1 0.024
inorganic cation transmembrane transport GO:0098662 50 0.023
negative regulation of biological process GO:0048519 304 0.023
Fly
metal ion transport GO:0030001 58 0.023
rna transport GO:0050658 2 0.022
cytoplasm organization GO:0007028 4 0.022
cellular amino acid metabolic process GO:0006520 7 0.022
vacuole organization GO:0007033 9 0.022
cellular protein catabolic process GO:0044257 4 0.022
cellular biosynthetic process GO:0044249 286 0.022
Fly
regulation of multicellular organism growth GO:0040014 4 0.022
centrosome organization GO:0051297 1 0.022
regulation of cellular amine metabolic process GO:0033238 0 0.021
vacuolar transport GO:0007034 2 0.021
notochord cell vacuolation GO:0060036 7 0.021
retina morphogenesis in camera type eye GO:0060042 79 0.021
rna metabolic process GO:0016070 219 0.021
blood vessel morphogenesis GO:0048514 216 0.021
regulation of rna metabolic process GO:0051252 224 0.020
maternal determination of anterior posterior axis embryo GO:0008358 4 0.020
protein acetylation GO:0006473 2 0.020
regulation of rna biosynthetic process GO:2001141 213 0.020
protein acylation GO:0043543 3 0.019
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.019
heterocycle metabolic process GO:0046483 290 0.019
Fly
cellular response to extracellular stimulus GO:0031668 2 0.019
Fly
nitrogen compound metabolic process GO:0006807 319 0.019
Fly
neurotransmitter transport GO:0006836 2 0.019
response to wounding GO:0009611 116 0.019
programmed cell death GO:0012501 119 0.019
regulation of endothelial cell proliferation GO:0001936 1 0.018
cation transport GO:0006812 81 0.018
synaptic vesicle localization GO:0097479 1 0.018
regulation of synapse organization GO:0050807 3 0.018
blood vessel development GO:0001568 246 0.018
regulation of gene expression GO:0010468 265 0.018
heart development GO:0007507 313 0.018
swim bladder development GO:0048794 19 0.018
positive regulation of transport GO:0051050 2 0.018
cell migration GO:0016477 237 0.018
Fly
synaptic growth at neuromuscular junction GO:0051124 2 0.018
centrosome duplication GO:0051298 1 0.017
cellular amine metabolic process GO:0044106 2 0.017
regulation of blood pressure GO:0008217 1 0.017
hepaticobiliary system development GO:0061008 98 0.017
spermatid differentiation GO:0048515 2 0.017
cellular component movement GO:0006928 335 0.017
Fly
female sex differentiation GO:0046660 4 0.017
inorganic ion transmembrane transport GO:0098660 57 0.017
negative regulation of cellular process GO:0048523 283 0.017
Fly
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.016
negative regulation of signaling GO:0023057 96 0.016
Fly
stem cell proliferation GO:0072089 4 0.016
reproduction GO:0000003 40 0.016
Fly
mitochondrion organization GO:0007005 4 0.016
cell aging GO:0007569 2 0.016
negative regulation of epithelial cell proliferation GO:0050680 1 0.016
establishment of rna localization GO:0051236 3 0.016
macromolecule modification GO:0043412 111 0.016
regulation of reactive oxygen species metabolic process GO:2000377 2 0.016
nik nf kappab signaling GO:0038061 1 0.016
muscle cell differentiation GO:0042692 139 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
nucleobase containing compound metabolic process GO:0006139 274 0.016
membrane invagination GO:0010324 1 0.016
cellular nitrogen compound metabolic process GO:0034641 290 0.015
Fly
cortical cytoskeleton organization GO:0030865 1 0.015
ovulation cycle GO:0042698 2 0.015
transmembrane transport GO:0055085 120 0.015
amine metabolic process GO:0009308 2 0.015
ribosomal small subunit biogenesis GO:0042274 2 0.015
response to chemical GO:0042221 320 0.015
dorsal ventral pattern formation GO:0009953 125 0.015
protein modification by small protein removal GO:0070646 1 0.015
pole plasm assembly GO:0007315 4 0.015
chordate embryonic development GO:0043009 271 0.015
negative regulation of programmed cell death GO:0043069 58 0.015
regionalization GO:0003002 274 0.015
atp catabolic process GO:0006200 4 0.015
ribonucleoside monophosphate catabolic process GO:0009158 4 0.015
extrinsic apoptotic signaling pathway GO:0097191 3 0.015
negative regulation of protein phosphorylation GO:0001933 4 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.015
negative regulation of apoptotic process GO:0043066 55 0.015
rna localization GO:0006403 4 0.015
regulation of programmed cell death GO:0043067 101 0.014
head development GO:0060322 303 0.014
nucleocytoplasmic transport GO:0006913 4 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
regulation of meiotic cell cycle GO:0051445 1 0.014
regulation of cell activation GO:0050865 1 0.014
regulation of cellular ph GO:0030641 1 0.014
neuron development GO:0048666 262 0.014
activation of mapk activity GO:0000187 3 0.014
proteasomal protein catabolic process GO:0010498 2 0.014
cell death GO:0008219 121 0.014
Worm
regulation of cell death GO:0010941 103 0.014
membrane fusion GO:0061025 2 0.014
Worm Fly
meiosis i GO:0007127 1 0.014
ovarian follicle development GO:0001541 2 0.014
modification dependent protein catabolic process GO:0019941 3 0.014
neuron neuron synaptic transmission GO:0007270 1 0.014
negative regulation of cellular catabolic process GO:0031330 3 0.014
regulation of reproductive process GO:2000241 4 0.014
protein homooligomerization GO:0051260 3 0.013
nucleoside monophosphate catabolic process GO:0009125 4 0.013
somitogenesis GO:0001756 87 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.013
regulation of nitrogen compound metabolic process GO:0051171 251 0.013
gamete generation GO:0007276 33 0.013
Fly
neuroblast proliferation GO:0007405 2 0.013
response to inorganic substance GO:0010035 38 0.013
single organism localization GO:1902578 225 0.013
transcription dna templated GO:0006351 181 0.013
histone h3 k4 methylation GO:0051568 2 0.013
regulation of erk1 and erk2 cascade GO:0070372 4 0.013
wound healing GO:0042060 90 0.013
oocyte anterior posterior axis specification GO:0007314 4 0.013
regulation of ph GO:0006885 3 0.013
cell cycle arrest GO:0007050 1 0.013
central nervous system development GO:0007417 387 0.013
nucleic acid metabolic process GO:0090304 244 0.013
muscle structure development GO:0061061 196 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
angiogenesis GO:0001525 158 0.013
regulation of apoptotic process GO:0042981 98 0.013
developmental programmed cell death GO:0010623 4 0.012
ovulation cycle process GO:0022602 2 0.012
regulation of inflammatory response GO:0050727 2 0.012
transcription from rna polymerase iii promoter GO:0006383 1 0.012
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.012
growth GO:0040007 174 0.012
developmental growth GO:0048589 166 0.012
positive regulation of apoptotic signaling pathway GO:2001235 1 0.012
positive regulation of neuron death GO:1901216 1 0.012
cell motility GO:0048870 244 0.012
Fly
regulation of signaling GO:0023051 235 0.012
Fly
cell morphogenesis involved in differentiation GO:0000904 195 0.012
lymphocyte proliferation GO:0046651 1 0.012
regulation of synapse assembly GO:0051963 3 0.012
cell part morphogenesis GO:0032990 246 0.012
regulation of stem cell proliferation GO:0072091 2 0.012
sequestering of metal ion GO:0051238 3 0.012
gland development GO:0048732 143 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.012
b cell activation GO:0042113 2 0.012
morphogenesis of an epithelium GO:0002009 333 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.012
protein complex disassembly GO:0043241 1 0.012
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.012
liver development GO:0001889 96 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
cell projection organization GO:0030030 284 0.012
gastrulation GO:0007369 208 0.012
cell surface receptor signaling pathway GO:0007166 325 0.012
Fly
axon cargo transport GO:0008088 2 0.011
organic acid metabolic process GO:0006082 31 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
immune system process GO:0002376 241 0.011
regulation of binding GO:0051098 3 0.011
regulation of cytoplasmic transport GO:1903649 4 0.011
intracellular signal transduction GO:0035556 85 0.011
cell morphogenesis GO:0000902 289 0.011
b cell mediated immunity GO:0019724 3 0.011
regulation of nervous system development GO:0051960 90 0.011
regulation of transcription dna templated GO:0006355 213 0.011
regulation of cytokine production GO:0001817 3 0.011
digestive tract morphogenesis GO:0048546 231 0.011
positive regulation of stem cell proliferation GO:2000648 1 0.011
striated muscle tissue development GO:0014706 110 0.011
positive regulation of cell cycle GO:0045787 3 0.011
notochord development GO:0030903 54 0.011
nuclear export GO:0051168 1 0.011
single organism metabolic process GO:0044710 217 0.011
Fly
dendrite guidance GO:0070983 0 0.011
axonogenesis GO:0007409 152 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
positive regulation of myeloid cell differentiation GO:0045639 2 0.011
positive regulation of neuron apoptotic process GO:0043525 1 0.011
myeloid cell development GO:0061515 32 0.011
purine nucleoside monophosphate catabolic process GO:0009128 4 0.011
homeostasis of number of cells GO:0048872 62 0.011
organelle assembly GO:0070925 110 0.011
Worm
anterior posterior pattern specification GO:0009952 152 0.011
regulation of receptor activity GO:0010469 2 0.011
organic cyclic compound biosynthetic process GO:1901362 223 0.011
Fly
intracellular mrna localization GO:0008298 1 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
apoptotic process involved in development GO:1902742 2 0.010
actin filament polymerization GO:0030041 2 0.010
exocytosis GO:0006887 1 0.010
negative regulation of reproductive process GO:2000242 3 0.010
cellular respiration GO:0045333 3 0.010
regulation of dna templated transcription in response to stress GO:0043620 0 0.010
cellular protein metabolic process GO:0044267 129 0.010
Fly
positive regulation of chromosome organization GO:2001252 1 0.010
positive regulation of epithelial cell proliferation GO:0050679 1 0.010
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.010
g2 dna damage checkpoint GO:0031572 3 0.010
stem cell division GO:0017145 1 0.010
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.010
regulation of blood vessel size GO:0050880 2 0.010

vps18 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.079
nervous system disease DOID:863 0 0.022
musculoskeletal system disease DOID:17 0 0.020
disease of cellular proliferation DOID:14566 0 0.018
muscle tissue disease DOID:66 0 0.016
myopathy DOID:423 0 0.016
muscular disease DOID:0080000 0 0.016
organ system cancer DOID:0050686 0 0.011
cancer DOID:162 0 0.011