Danio rerio

0 known processes

wdr45

WD repeat domain 45

(Aliases: zgc:77017,MGC56345,zgc:56345)

wdr45 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
spindle assembly GO:0051225 2 0.132
aging GO:0007568 2 0.131
protein polymerization GO:0051258 4 0.107
meiotic nuclear division GO:0007126 4 0.090
meiotic chromosome segregation GO:0045132 3 0.083
maintenance of location GO:0051235 4 0.081
cellular ketone metabolic process GO:0042180 11 0.081
larval development GO:0002164 2 0.076
lipid storage GO:0019915 1 0.074
autophagy GO:0006914 4 0.071
stem cell proliferation GO:0072089 4 0.067
chromosome segregation GO:0007059 12 0.067
multicellular organism growth GO:0035264 4 0.059
meiotic cell cycle process GO:1903046 3 0.055
cellular response to external stimulus GO:0071496 2 0.052
single organism metabolic process GO:0044710 217 0.051
negative regulation of cellular process GO:0048523 283 0.050
organelle organization GO:0006996 227 0.048
spindle assembly involved in mitosis GO:0090307 1 0.046
skeletal system development GO:0001501 181 0.045
embryonic limb morphogenesis GO:0030326 2 0.045
embryo development ending in birth or egg hatching GO:0009792 271 0.044
regulation of cellular ketone metabolic process GO:0010565 7 0.043
phagocytosis GO:0006909 3 0.043
regulation of microtubule depolymerization GO:0031114 1 0.039
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.038
cellular component disassembly GO:0022411 1 0.038
response to stress GO:0006950 263 0.038
regulation of stem cell proliferation GO:0072091 2 0.038
regulation of carbohydrate metabolic process GO:0006109 4 0.037
response to chemical GO:0042221 320 0.037
lipid catabolic process GO:0016042 4 0.036
regulation of intracellular ph GO:0051453 1 0.036
negative regulation of biological process GO:0048519 304 0.034
cellular response to light stimulus GO:0071482 4 0.034
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.034
regulation of protein depolymerization GO:1901879 1 0.034
cellular response to starvation GO:0009267 1 0.033
positive regulation of stem cell proliferation GO:2000648 1 0.033
atp synthesis coupled electron transport GO:0042773 1 0.033
positive regulation of transport GO:0051050 2 0.032
cellular carbohydrate metabolic process GO:0044262 4 0.032
cellular response to nutrient levels GO:0031669 2 0.032
response to abiotic stimulus GO:0009628 122 0.031
membrane fusion GO:0061025 2 0.031
central nervous system development GO:0007417 387 0.031
protein complex disassembly GO:0043241 1 0.031
macroautophagy GO:0016236 1 0.030
organonitrogen compound metabolic process GO:1901564 74 0.030
regulation of mesenchymal cell proliferation GO:0010464 1 0.030
locomotion GO:0040011 313 0.029
small molecule metabolic process GO:0044281 77 0.029
organic cyclic compound metabolic process GO:1901360 301 0.029
amine metabolic process GO:0009308 2 0.028
microtubule depolymerization GO:0007019 1 0.028
protein metabolic process GO:0019538 183 0.028
respiratory electron transport chain GO:0022904 2 0.027
synaptic vesicle localization GO:0097479 1 0.027
macromolecular complex disassembly GO:0032984 1 0.027
mesenchymal cell proliferation GO:0010463 1 0.027
response to drug GO:0042493 3 0.027
guanosine containing compound metabolic process GO:1901068 4 0.026
protein depolymerization GO:0051261 1 0.026
lateral inhibition GO:0046331 1 0.025
cellular response to radiation GO:0071478 4 0.025
growth GO:0040007 174 0.025
ubiquitin dependent protein catabolic process GO:0006511 3 0.024
protein localization to plasma membrane GO:0072659 1 0.024
positive regulation of cell cycle GO:0045787 3 0.024
establishment of protein localization to organelle GO:0072594 4 0.024
cellular protein modification process GO:0006464 100 0.024
modification dependent protein catabolic process GO:0019941 3 0.024
mechanosensory behavior GO:0007638 2 0.024
generation of neurons GO:0048699 385 0.024
cell part morphogenesis GO:0032990 246 0.024
carboxylic acid metabolic process GO:0019752 22 0.023
cellular amine metabolic process GO:0044106 2 0.023
cellular protein catabolic process GO:0044257 4 0.022
response to topologically incorrect protein GO:0035966 2 0.022
synaptic vesicle transport GO:0048489 1 0.022
regulation of cellular ph GO:0030641 1 0.022
carbohydrate biosynthetic process GO:0016051 1 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.022
developmental growth GO:0048589 166 0.022
organic acid metabolic process GO:0006082 31 0.022
neuroblast proliferation GO:0007405 2 0.022
response to external stimulus GO:0009605 264 0.022
cell morphogenesis GO:0000902 289 0.021
cellular respiration GO:0045333 3 0.021
regulation of protein complex disassembly GO:0043244 1 0.021
positive regulation of secretion by cell GO:1903532 1 0.021
microtubule polymerization or depolymerization GO:0031109 3 0.021
cellular component biogenesis GO:0044085 178 0.021
cellular aromatic compound metabolic process GO:0006725 295 0.021
regulation of protein targeting GO:1903533 2 0.021
gtp metabolic process GO:0046039 4 0.020
regulation of multicellular organism growth GO:0040014 4 0.020
macromolecule modification GO:0043412 111 0.020
regulation of cellular amine metabolic process GO:0033238 0 0.020
regulation of ph GO:0006885 3 0.020
establishment of synaptic vesicle localization GO:0097480 1 0.020
signal transduction GO:0007165 455 0.020
protein polyubiquitination GO:0000209 4 0.020
single organism membrane fusion GO:0044801 2 0.020
cellular component assembly GO:0022607 170 0.020
transport GO:0006810 220 0.020
cellular component movement GO:0006928 335 0.020
regulation of synaptic plasticity GO:0048167 1 0.020
protein import GO:0017038 3 0.020
double strand break repair GO:0006302 3 0.020
oxoacid metabolic process GO:0043436 31 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.019
cellular protein complex disassembly GO:0043624 1 0.019
negative regulation of protein phosphorylation GO:0001933 4 0.019
regulation of metal ion transport GO:0010959 4 0.019
modification dependent macromolecule catabolic process GO:0043632 3 0.019
regulation of protein catabolic process GO:0042176 1 0.019
negative regulation of protein kinase activity GO:0006469 4 0.019
regulation of circadian rhythm GO:0042752 4 0.019
regulation of response to stimulus GO:0048583 269 0.018
organelle fusion GO:0048284 3 0.018
cellular nitrogen compound metabolic process GO:0034641 290 0.018
negative regulation of kinase activity GO:0033673 4 0.018
positive regulation of cellular catabolic process GO:0031331 3 0.018
cellular amino acid metabolic process GO:0006520 7 0.018
regulation of cellular component organization GO:0051128 86 0.018
regulation of microtubule cytoskeleton organization GO:0070507 3 0.018
extrinsic apoptotic signaling pathway GO:0097191 3 0.018
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.018
developmental growth involved in morphogenesis GO:0060560 86 0.018
cellular response to extracellular stimulus GO:0031668 2 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
cellular response to topologically incorrect protein GO:0035967 2 0.018
cytokinesis GO:0000910 3 0.018
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.018
production of molecular mediator of immune response GO:0002440 2 0.017
electron transport chain GO:0022900 2 0.017
regionalization GO:0003002 274 0.017
neurotransmitter transport GO:0006836 2 0.017
positive regulation of blood circulation GO:1903524 2 0.017
intracellular signal transduction GO:0035556 85 0.017
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.017
organelle assembly GO:0070925 110 0.017
regulation of tube size GO:0035150 2 0.017
regulation of establishment of protein localization GO:0070201 4 0.017
cell projection organization GO:0030030 284 0.017
cellular lipid catabolic process GO:0044242 3 0.017
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.017
oxidative phosphorylation GO:0006119 1 0.017
meiosis i GO:0007127 1 0.017
organic acid catabolic process GO:0016054 3 0.017
protein acylation GO:0043543 3 0.017
connective tissue development GO:0061448 99 0.017
positive regulation of biological process GO:0048518 253 0.017
rna transport GO:0050658 2 0.016
adult behavior GO:0030534 2 0.016
cartilage development GO:0051216 96 0.016
negative regulation of mapk cascade GO:0043409 4 0.016
internal peptidyl lysine acetylation GO:0018393 2 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.016
positive regulation of secretion GO:0051047 1 0.016
microtubule polymerization GO:0046785 2 0.016
response to uv GO:0009411 3 0.016
positive regulation of catabolic process GO:0009896 4 0.016
proteasomal protein catabolic process GO:0010498 2 0.016
gastrulation GO:0007369 208 0.016
hormone transport GO:0009914 2 0.016
guanosine containing compound catabolic process GO:1901069 2 0.016
regulation of biological quality GO:0065008 263 0.016
regulation of organ growth GO:0046620 3 0.016
single organism organelle organization GO:1902589 199 0.016
macromolecule deacylation GO:0098732 3 0.016
gtp catabolic process GO:0006184 2 0.016
mitochondrial atp synthesis coupled electron transport GO:0042775 1 0.016
regulation of cell shape GO:0008360 1 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
cellular response to stress GO:0033554 62 0.015
regulation of anatomical structure morphogenesis GO:0022603 130 0.015
appendage development GO:0048736 80 0.015
cellular amide metabolic process GO:0043603 4 0.015
regulation of systemic arterial blood pressure GO:0003073 1 0.015
peptidyl lysine acetylation GO:0018394 2 0.015
rna localization GO:0006403 4 0.015
chromosome organization involved in meiosis GO:0070192 1 0.015
protein acetylation GO:0006473 2 0.015
mitochondrion organization GO:0007005 4 0.015
positive regulation of signaling GO:0023056 56 0.015
neuron differentiation GO:0030182 353 0.015
regulation of blood pressure GO:0008217 1 0.015
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.015
secondary metabolic process GO:0019748 3 0.015
system process GO:0003008 185 0.015
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.014
cellular macromolecule metabolic process GO:0044260 391 0.014
positive regulation of apoptotic signaling pathway GO:2001235 1 0.014
i kappab kinase nf kappab signaling GO:0007249 4 0.014
regulation of developmental process GO:0050793 247 0.014
protein homooligomerization GO:0051260 3 0.014
nitrogen compound metabolic process GO:0006807 319 0.014
erk1 and erk2 cascade GO:0070371 4 0.014
dna templated transcription elongation GO:0006354 3 0.014
vacuole organization GO:0007033 9 0.014
membrane invagination GO:0010324 1 0.014
regulation of cytoplasmic transport GO:1903649 4 0.014
mitotic cell cycle GO:0000278 64 0.014
ph reduction GO:0045851 1 0.014
morphogenesis of an epithelium GO:0002009 333 0.014
cellular response to chemical stimulus GO:0070887 157 0.014
regulation of protein transport GO:0051223 3 0.013
protein secretion GO:0009306 1 0.013
regulation of reproductive process GO:2000241 4 0.013
negative regulation of chromosome organization GO:2001251 1 0.013
response to corticosteroid GO:0031960 1 0.013
positive regulation of stress activated mapk cascade GO:0032874 3 0.013
convergent extension GO:0060026 118 0.013
spermatid differentiation GO:0048515 2 0.013
regulation of blood vessel size GO:0050880 2 0.013
neurotransmitter secretion GO:0007269 2 0.013
cilium morphogenesis GO:0060271 85 0.013
cellular component morphogenesis GO:0032989 336 0.013
negative regulation of cellular catabolic process GO:0031330 3 0.013
lipid homeostasis GO:0055088 3 0.013
regulation of binding GO:0051098 3 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
spermatid development GO:0007286 2 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
regulation of hormone secretion GO:0046883 2 0.013
positive regulation of cell activation GO:0050867 1 0.013
gene expression GO:0010467 252 0.013
response to vitamin GO:0033273 3 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
female meiotic division GO:0007143 2 0.013
regulation of oocyte development GO:0060281 3 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
vesicle localization GO:0051648 27 0.013
intracellular mrna localization GO:0008298 1 0.013
compound eye development GO:0048749 2 0.013
negative regulation of epithelial cell proliferation GO:0050680 1 0.012
synaptic vesicle recycling GO:0036465 1 0.012
positive regulation of cellular process GO:0048522 201 0.012
taxis GO:0042330 109 0.012
regulation of multicellular organismal process GO:0051239 277 0.012
single organism nuclear import GO:1902593 3 0.012
hormone secretion GO:0046879 2 0.012
regulation of synaptic vesicle transport GO:1902803 1 0.012
organelle localization GO:0051640 49 0.012
negative regulation of neural precursor cell proliferation GO:2000178 1 0.012
internal protein amino acid acetylation GO:0006475 2 0.012
cell matrix adhesion GO:0007160 4 0.012
regulation of epithelial cell proliferation GO:0050678 3 0.012
cellular localization GO:0051641 97 0.012
phagocytosis engulfment GO:0006911 1 0.012
fatty acid catabolic process GO:0009062 1 0.012
protein dephosphorylation GO:0006470 3 0.012
cell substrate adhesion GO:0031589 4 0.012
regulation of dna recombination GO:0000018 2 0.012
male meiosis GO:0007140 2 0.012
heterocycle metabolic process GO:0046483 290 0.012
peptide metabolic process GO:0006518 1 0.012
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 1 0.012
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.012
phosphorylation GO:0016310 69 0.012
rna 3 end processing GO:0031123 2 0.012
neuron projection development GO:0031175 180 0.012
regulation of mrna processing GO:0050684 3 0.012
phosphatidylinositol mediated signaling GO:0048015 2 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
pathway restricted smad protein phosphorylation GO:0060389 1 0.011
positive regulation of carbohydrate metabolic process GO:0045913 1 0.011
alternative mrna splicing via spliceosome GO:0000380 1 0.011
protein modification process GO:0036211 100 0.011
golgi vesicle transport GO:0048193 3 0.011
mitotic nuclear division GO:0007067 18 0.011
alpha amino acid metabolic process GO:1901605 3 0.011
mitotic dna integrity checkpoint GO:0044774 4 0.011
regulation of rna biosynthetic process GO:2001141 213 0.011
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
lytic vacuole organization GO:0080171 1 0.011
regulation of primary metabolic process GO:0080090 311 0.011
regulation of fatty acid metabolic process GO:0019217 1 0.011
digestive tract development GO:0048565 265 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.011
steroid hormone secretion GO:0035929 1 0.011
response to organic substance GO:0010033 153 0.011
cell morphogenesis involved in differentiation GO:0000904 195 0.011
regulation of neurogenesis GO:0050767 87 0.011
regulation of receptor activity GO:0010469 2 0.011
single organism localization GO:1902578 225 0.011
regulation of mitotic cell cycle GO:0007346 25 0.011
cell cycle arrest GO:0007050 1 0.011
epithelial cell morphogenesis GO:0003382 2 0.011
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.011
regulation of endothelial cell differentiation GO:0045601 3 0.011
chemical homeostasis GO:0048878 49 0.011
regulation of cell development GO:0060284 100 0.011
heart development GO:0007507 313 0.011
ribonucleoside monophosphate catabolic process GO:0009158 4 0.011
regulation of erk1 and erk2 cascade GO:0070372 4 0.011
response to unfolded protein GO:0006986 2 0.011
circadian sleep wake cycle process GO:0022410 2 0.011
nuclear import GO:0051170 3 0.011
protein k48 linked ubiquitination GO:0070936 1 0.011
peptide transport GO:0015833 1 0.011
appendage morphogenesis GO:0035107 56 0.011
mitotic g2 dna damage checkpoint GO:0007095 3 0.011
synaptic vesicle endocytosis GO:0048488 1 0.011
localization within membrane GO:0051668 1 0.011
stem cell maintenance GO:0019827 4 0.011
axon development GO:0061564 166 0.011
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.010
regulation of protein binding GO:0043393 3 0.010
regulation of sodium ion transport GO:0002028 2 0.010
cellular response to molecule of bacterial origin GO:0071219 3 0.010
positive regulation of nucleoside metabolic process GO:0045979 1 0.010
axis elongation GO:0003401 31 0.010
olfactory lobe development GO:0021988 4 0.010
specification of symmetry GO:0009799 204 0.010
post embryonic organ development GO:0048569 4 0.010
fatty acid oxidation GO:0019395 1 0.010
peptidyl serine phosphorylation GO:0018105 1 0.010
histone h3 k4 methylation GO:0051568 2 0.010
inositol lipid mediated signaling GO:0048017 2 0.010
digestive tract morphogenesis GO:0048546 231 0.010
fatty acid beta oxidation GO:0006635 1 0.010
phosphorus metabolic process GO:0006793 109 0.010
adherens junction organization GO:0034332 4 0.010
regulation of apoptotic process GO:0042981 98 0.010
positive regulation of protein complex assembly GO:0031334 2 0.010
establishment of rna localization GO:0051236 3 0.010
regulation of response to biotic stimulus GO:0002831 2 0.010
heart looping GO:0001947 94 0.010
digestive system development GO:0055123 289 0.010
interspecies interaction between organisms GO:0044419 4 0.010
regulation of cell communication GO:0010646 232 0.010
regulation of cellular protein catabolic process GO:1903362 1 0.010
negative regulation of muscle cell differentiation GO:0051148 1 0.010
neuron fate determination GO:0048664 2 0.010
forebrain regionalization GO:0021871 4 0.010
negative regulation of multi organism process GO:0043901 3 0.010

wdr45 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.025
inherited metabolic disorder DOID:655 0 0.025
disease of anatomical entity DOID:7 0 0.021
lysosomal storage disease DOID:3211 0 0.016
nervous system disease DOID:863 0 0.014
disease of cellular proliferation DOID:14566 0 0.012