Danio rerio

0 known processes

wdr5

WD repeat domain 5

(Aliases: wu:fk47f04,zgc:76895,zgc:56591)

wdr5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular macromolecule metabolic process GO:0044260 391 0.582
Human Mouse Worm Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.435
Mouse
cellular biosynthetic process GO:0044249 286 0.398
Mouse
regulation of rna biosynthetic process GO:2001141 213 0.314
Mouse
negative regulation of biological process GO:0048519 304 0.307
Worm Fly
regulation of metabolic process GO:0019222 359 0.270
Mouse
regulation of developmental process GO:0050793 247 0.192
Worm
biosynthetic process GO:0009058 294 0.189
Mouse
digestive tract development GO:0048565 265 0.187
cellular nitrogen compound biosynthetic process GO:0044271 218 0.184
Mouse
positive regulation of biological process GO:0048518 253 0.181
Mouse
larval development GO:0002164 2 0.171
Worm
organic cyclic compound metabolic process GO:1901360 301 0.171
Mouse
negative regulation of cellular process GO:0048523 283 0.165
Fly
regulation of cellular metabolic process GO:0031323 320 0.164
Mouse
macromolecule biosynthetic process GO:0009059 227 0.157
Mouse
rna biosynthetic process GO:0032774 181 0.156
Mouse
organic substance biosynthetic process GO:1901576 289 0.148
Mouse
gene expression GO:0010467 252 0.141
Mouse
locomotion GO:0040011 313 0.139
Worm
single organism organelle organization GO:1902589 199 0.135
Human Mouse Worm Fly
digestive system development GO:0055123 289 0.127
regulation of cellular biosynthetic process GO:0031326 245 0.127
Mouse
heterocycle metabolic process GO:0046483 290 0.126
Mouse
regulation of biosynthetic process GO:0009889 250 0.124
Mouse
nucleic acid metabolic process GO:0090304 244 0.119
Mouse
response to chemical GO:0042221 320 0.113
regulation of nitrogen compound metabolic process GO:0051171 251 0.110
Mouse
organelle organization GO:0006996 227 0.100
Human Mouse Worm Fly
regulation of gene expression GO:0010468 265 0.098
Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.098
Mouse
rna metabolic process GO:0016070 219 0.098
Mouse
meiotic nuclear division GO:0007126 4 0.095
cellular macromolecule biosynthetic process GO:0034645 224 0.094
Mouse
negative regulation of response to stimulus GO:0048585 104 0.093
regulation of transcription dna templated GO:0006355 213 0.091
Mouse
single organism reproductive process GO:0044702 40 0.088
Worm
regulation of signal transduction GO:0009966 225 0.087
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.085
Mouse
multicellular organism growth GO:0035264 4 0.084
regulation of gene expression epigenetic GO:0040029 11 0.083
positive regulation of cell cycle GO:0045787 3 0.078
regulation of multicellular organism growth GO:0040014 4 0.077
macromolecular complex disassembly GO:0032984 1 0.077
positive regulation of cellular process GO:0048522 201 0.077
Mouse
protein localization to nucleus GO:0034504 3 0.071
heterocycle biosynthetic process GO:0018130 215 0.071
Mouse
transcription dna templated GO:0006351 181 0.071
Mouse
regulation of nucleic acid templated transcription GO:1903506 213 0.071
Mouse
immune system process GO:0002376 241 0.069
single organism metabolic process GO:0044710 217 0.064
Human Mouse Worm Fly
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.064
Mouse
multi organism process GO:0051704 134 0.063
cellular protein metabolic process GO:0044267 129 0.063
Human Mouse Worm Fly
internal protein amino acid acetylation GO:0006475 2 0.061
Human Fly
cellular aromatic compound metabolic process GO:0006725 295 0.061
Mouse
cellular component disassembly GO:0022411 1 0.061
nuclear migration GO:0007097 3 0.059
protein complex disassembly GO:0043241 1 0.059
nitrogen compound metabolic process GO:0006807 319 0.057
Mouse
organic cyclic compound biosynthetic process GO:1901362 223 0.057
Mouse
cell morphogenesis GO:0000902 289 0.055
nucleic acid templated transcription GO:0097659 181 0.052
Mouse
negative regulation of biosynthetic process GO:0009890 55 0.051
regionalization GO:0003002 274 0.051
signal transduction GO:0007165 455 0.050
digestive tract morphogenesis GO:0048546 231 0.048
nucleobase containing compound metabolic process GO:0006139 274 0.047
Mouse
positive regulation of chromatin modification GO:1903310 1 0.047
covalent chromatin modification GO:0016569 20 0.047
Human Mouse Worm Fly
positive regulation of gene expression GO:0010628 71 0.046
Mouse
protein acetylation GO:0006473 2 0.044
Human Fly
regulation of biological quality GO:0065008 263 0.043
developmental process involved in reproduction GO:0003006 27 0.043
Worm
regulation of cell shape GO:0008360 1 0.042
nucleobase containing compound biosynthetic process GO:0034654 205 0.040
Mouse
aging GO:0007568 2 0.040
Worm
negative regulation of gene expression GO:0010629 65 0.040
sexual reproduction GO:0019953 36 0.040
autophagy GO:0006914 4 0.039
macromolecular complex subunit organization GO:0043933 74 0.038
Human Mouse Worm Fly
positive regulation of macromolecule metabolic process GO:0010604 93 0.038
Mouse
neurological system process GO:0050877 62 0.038
negative regulation of cell communication GO:0010648 96 0.037
reproductive process GO:0022414 40 0.037
Worm
establishment of nucleus localization GO:0040023 7 0.037
generation of neurons GO:0048699 385 0.036
Rat
positive regulation of cellular biosynthetic process GO:0031328 68 0.036
Mouse
gene silencing GO:0016458 4 0.036
mitotic cell cycle GO:0000278 64 0.036
Fly
programmed cell death GO:0012501 119 0.035
Worm
regulation of translational initiation GO:0006446 1 0.034
nuclear transport GO:0051169 4 0.034
segmentation GO:0035282 97 0.033
neuron differentiation GO:0030182 353 0.033
Rat
cell death GO:0008219 121 0.033
Worm
positive regulation of cellular component biogenesis GO:0044089 3 0.033
establishment of localization GO:0051234 244 0.032
negative regulation of signal transduction GO:0009968 94 0.032
regulation of protein complex assembly GO:0043254 3 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.031
protein import into nucleus GO:0006606 3 0.031
regulation of primary metabolic process GO:0080090 311 0.030
Mouse
translational initiation GO:0006413 3 0.030
regulation of establishment of protein localization GO:0070201 4 0.030
protein localization GO:0008104 40 0.030
localization of cell GO:0051674 244 0.029
Worm
cell part morphogenesis GO:0032990 246 0.029
peptidyl lysine acetylation GO:0018394 2 0.028
Human Fly
aromatic compound biosynthetic process GO:0019438 217 0.028
Mouse
regulation of cellular ketone metabolic process GO:0010565 7 0.028
Mouse
cognition GO:0050890 1 0.028
negative regulation of metabolic process GO:0009892 86 0.027
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.027
rna localization GO:0006403 4 0.026
stem cell maintenance GO:0019827 4 0.026
chromatin organization GO:0006325 22 0.026
Human Mouse Worm Fly
small molecule metabolic process GO:0044281 77 0.025
Mouse
regulation of autophagy GO:0010506 3 0.025
nucleocytoplasmic transport GO:0006913 4 0.025
cellular nitrogen compound metabolic process GO:0034641 290 0.025
Mouse
g2 m transition of mitotic cell cycle GO:0000086 4 0.025
death GO:0016265 121 0.025
Worm
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.025
Mouse
cell surface receptor signaling pathway GO:0007166 325 0.025
response to nutrient GO:0007584 3 0.025
cell cycle GO:0007049 93 0.024
Fly
cytoskeleton organization GO:0007010 96 0.024
single organism localization GO:1902578 225 0.024
alternative mrna splicing via spliceosome GO:0000380 1 0.024
organonitrogen compound metabolic process GO:1901564 74 0.023
cell projection morphogenesis GO:0048858 244 0.023
regulation of protein transport GO:0051223 3 0.023
cellular amine metabolic process GO:0044106 2 0.023
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.023
positive regulation of glial cell differentiation GO:0045687 1 0.023
dorsal ventral pattern formation GO:0009953 125 0.022
internal peptidyl lysine acetylation GO:0018393 2 0.022
Human Fly
protein metabolic process GO:0019538 183 0.022
Human Mouse Worm Fly
transport GO:0006810 220 0.022
cellular response to chemical stimulus GO:0070887 157 0.022
regulation of cell communication GO:0010646 232 0.022
negative regulation of rna metabolic process GO:0051253 48 0.022
regulation of response to stress GO:0080134 36 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.021
apoptotic process GO:0006915 116 0.021
Worm
cell cycle process GO:0022402 53 0.021
Fly
protein import GO:0017038 3 0.021
response to stress GO:0006950 263 0.021
Fly
intracellular mrna localization GO:0008298 1 0.021
positive regulation of nucleic acid templated transcription GO:1903508 57 0.021
Mouse
single organism nuclear import GO:1902593 3 0.021
microtubule organizing center organization GO:0031023 1 0.021
fertilization GO:0009566 3 0.021
mitotic cell cycle process GO:1903047 48 0.021
Fly
negative regulation of cellular biosynthetic process GO:0031327 55 0.021
regulation of apoptotic process GO:0042981 98 0.020
cellular component assembly GO:0022607 170 0.020
negative regulation of cellular metabolic process GO:0031324 77 0.020
negative regulation of cell differentiation GO:0045596 46 0.020
positive regulation of biosynthetic process GO:0009891 68 0.020
Mouse
hemopoiesis GO:0030097 183 0.020
protein polyubiquitination GO:0000209 4 0.020
nuclear import GO:0051170 3 0.020
cellular ketone metabolic process GO:0042180 11 0.020
Mouse
protein methylation GO:0006479 13 0.019
Human Mouse Worm Fly
intracellular signal transduction GO:0035556 85 0.019
amine metabolic process GO:0009308 2 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.019
Mouse
positive regulation of gliogenesis GO:0014015 2 0.019
growth GO:0040007 174 0.019
response to wounding GO:0009611 116 0.019
regulation of intracellular signal transduction GO:1902531 57 0.019
regulation of cellular component organization GO:0051128 86 0.019
regulation of dna metabolic process GO:0051052 11 0.019
cell morphogenesis involved in differentiation GO:0000904 195 0.019
regulation of cellular protein metabolic process GO:0032268 52 0.019
negative regulation of signaling GO:0023057 96 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.018
determination of bilateral symmetry GO:0009855 204 0.018
multi organism reproductive process GO:0044703 36 0.018
cellular response to extracellular stimulus GO:0031668 2 0.018
positive regulation of cellular metabolic process GO:0031325 94 0.018
Mouse
positive regulation of dna metabolic process GO:0051054 1 0.018
protein modification process GO:0036211 100 0.018
Human Mouse Worm Fly
negative regulation of intracellular signal transduction GO:1902532 22 0.017
protein k63 linked ubiquitination GO:0070534 2 0.017
response to drug GO:0042493 3 0.017
g1 s transition of mitotic cell cycle GO:0000082 1 0.017
ncrna metabolic process GO:0034660 12 0.017
regulation of mitotic cell cycle GO:0007346 25 0.017
Fly
muscle organ development GO:0007517 101 0.017
positive regulation of mrna splicing via spliceosome GO:0048026 1 0.017
macromolecule modification GO:0043412 111 0.017
Human Mouse Worm Fly
cellular response to external stimulus GO:0071496 2 0.017
developmental growth GO:0048589 166 0.017
cell cycle g2 m phase transition GO:0044839 4 0.017
regulation of rna metabolic process GO:0051252 224 0.016
Mouse
regulation of glial cell differentiation GO:0045685 4 0.016
cellular component biogenesis GO:0044085 178 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
phagocytosis GO:0006909 3 0.016
phosphorylation GO:0016310 69 0.016
muscle structure development GO:0061061 196 0.016
positive regulation of rna metabolic process GO:0051254 59 0.016
Mouse
transcription from rna polymerase iii promoter GO:0006383 1 0.016
anterior posterior pattern specification GO:0009952 152 0.016
synaptic growth at neuromuscular junction GO:0051124 2 0.016
transcription from rna polymerase ii promoter GO:0006366 80 0.016
Mouse
response to carbohydrate GO:0009743 3 0.016
positive regulation of developmental process GO:0051094 50 0.016
protein targeting to nucleus GO:0044744 3 0.016
behavior GO:0007610 74 0.016
central nervous system development GO:0007417 387 0.015
regulation of response to stimulus GO:0048583 269 0.015
muscle cell differentiation GO:0042692 139 0.015
regulation of cytoplasmic transport GO:1903649 4 0.015
oxoacid metabolic process GO:0043436 31 0.015
neuron development GO:0048666 262 0.015
Rat
cell motility GO:0048870 244 0.015
Worm
mitotic cell cycle phase transition GO:0044772 9 0.015
Fly
positive regulation of cell differentiation GO:0045597 30 0.015
carbohydrate biosynthetic process GO:0016051 1 0.015
Mouse
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.014
establishment of protein localization to organelle GO:0072594 4 0.014
protein polymerization GO:0051258 4 0.014
single organism biosynthetic process GO:0044711 71 0.014
Mouse
chromatin modification GO:0016568 21 0.014
Human Mouse Worm Fly
response to external stimulus GO:0009605 264 0.014
regulation of programmed cell death GO:0043067 101 0.014
cellular protein complex localization GO:0034629 1 0.014
3 utr mediated mrna stabilization GO:0070935 3 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
regulation of intracellular protein transport GO:0033157 3 0.014
regulation of cytokine production GO:0001817 3 0.014
homeostatic process GO:0042592 142 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.014
gamete generation GO:0007276 33 0.014
macromolecule methylation GO:0043414 19 0.014
Human Mouse Worm Fly
homeostasis of number of cells GO:0048872 62 0.014
cell proliferation GO:0008283 80 0.014
mrna metabolic process GO:0016071 20 0.014
negative regulation of cell death GO:0060548 60 0.014
hematopoietic or lymphoid organ development GO:0048534 191 0.014
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.013
Mouse
system process GO:0003008 185 0.013
positive regulation of metabolic process GO:0009893 108 0.013
Mouse
tube morphogenesis GO:0035239 349 0.013
negative regulation of macromolecule metabolic process GO:0010605 76 0.013
cellular macromolecule localization GO:0070727 21 0.013
organic acid metabolic process GO:0006082 31 0.013
positive regulation of mrna metabolic process GO:1903313 2 0.013
spliceosomal snrnp assembly GO:0000387 2 0.013
negative regulation of apoptotic process GO:0043066 55 0.013
mitotic cell cycle embryonic GO:0045448 2 0.013
mitotic nuclear envelope reassembly GO:0007084 2 0.013
sex determination GO:0007530 1 0.013
regulation of cell death GO:0010941 103 0.012
cytokinesis GO:0000910 3 0.012
meiotic cell cycle process GO:1903046 3 0.012
protein alkylation GO:0008213 13 0.012
Human Mouse Worm Fly
pronuclear migration GO:0035046 1 0.012
embryonic digestive tract morphogenesis GO:0048557 3 0.012
immune system development GO:0002520 191 0.012
regulation of response to nutrient levels GO:0032107 1 0.012
regulation of anatomical structure morphogenesis GO:0022603 130 0.012
cell aging GO:0007569 2 0.012
germ cell development GO:0007281 22 0.012
negative regulation of rna biosynthetic process GO:1902679 45 0.012
mrna catabolic process GO:0006402 6 0.012
response to other organism GO:0051707 97 0.012
stem cell differentiation GO:0048863 117 0.012
cellular localization GO:0051641 97 0.012
regulation of protein targeting GO:1903533 2 0.012
dna catabolic process GO:0006308 1 0.012
organism emergence from protective structure GO:0071684 4 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.012
Mouse
skin development GO:0043588 54 0.012
response to hexose GO:0009746 3 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.012
heart development GO:0007507 313 0.012
negative regulation of cell cycle process GO:0010948 9 0.012
Fly
organelle localization GO:0051640 49 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
production of molecular mediator of immune response GO:0002440 2 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.011
regulation of protein localization to nucleus GO:1900180 2 0.011
response to monosaccharide GO:0034284 3 0.011
regulation of cell differentiation GO:0045595 142 0.011
striated muscle tissue development GO:0014706 110 0.011
chromosome organization GO:0051276 31 0.011
Human Mouse Worm Fly
positive regulation of multicellular organismal process GO:0051240 52 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.011
histone modification GO:0016570 20 0.011
Human Mouse Worm Fly
stem cell proliferation GO:0072089 4 0.011
nuclear pore organization GO:0006999 2 0.011
positive regulation of chromosome organization GO:2001252 1 0.011
response to external biotic stimulus GO:0043207 97 0.011
rna transport GO:0050658 2 0.011
determination of dorsal ventral asymmetry GO:0048262 34 0.010
negative regulation of programmed cell death GO:0043069 58 0.010
regulation of meiotic cell cycle GO:0051445 1 0.010
double strand break repair GO:0006302 3 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
cell substrate junction assembly GO:0007044 2 0.010
cell cycle g1 s phase transition GO:0044843 1 0.010
regulation of dna replication GO:0006275 3 0.010
regulation of protein catabolic process GO:0042176 1 0.010
mitotic metaphase plate congression GO:0007080 1 0.010
specification of symmetry GO:0009799 204 0.010
response to corticosteroid GO:0031960 1 0.010
cellular protein modification process GO:0006464 100 0.010
Human Mouse Worm Fly
protein complex localization GO:0031503 1 0.010
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.010
response to glucose GO:0009749 3 0.010

wdr5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org