Danio rerio

14 known processes

wtap

Wilms tumor 1 associated protein

(Aliases: zgc:66202,wu:fi29a09)

wtap biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic cyclic compound metabolic process GO:1901360 301 0.401
Human
positive regulation of biological process GO:0048518 253 0.378
regulation of rna metabolic process GO:0051252 224 0.304
Human
regulation of macromolecule metabolic process GO:0060255 317 0.252
Human
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.241
immune system development GO:0002520 191 0.215
nucleic acid metabolic process GO:0090304 244 0.212
Human
gene expression GO:0010467 252 0.206
Human
cellular nitrogen compound metabolic process GO:0034641 290 0.206
Human
nucleobase containing compound metabolic process GO:0006139 274 0.204
Human
heart development GO:0007507 313 0.177
positive regulation of cellular process GO:0048522 201 0.175
regulation of nitrogen compound metabolic process GO:0051171 251 0.174
Human
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.172
Human
hemopoiesis GO:0030097 183 0.161
rna metabolic process GO:0016070 219 0.159
Human
cellular macromolecule biosynthetic process GO:0034645 224 0.149
regulation of rna biosynthetic process GO:2001141 213 0.146
regulation of nucleic acid templated transcription GO:1903506 213 0.145
segmentation GO:0035282 97 0.135
cellular component morphogenesis GO:0032989 336 0.133
regulation of transcription dna templated GO:0006355 213 0.126
nitrogen compound metabolic process GO:0006807 319 0.126
Human
cellular nitrogen compound biosynthetic process GO:0044271 218 0.122
response to chemical GO:0042221 320 0.110
heterocycle metabolic process GO:0046483 290 0.108
Human
sensory organ development GO:0007423 393 0.105
hematopoietic or lymphoid organ development GO:0048534 191 0.104
positive regulation of metabolic process GO:0009893 108 0.096
regulation of primary metabolic process GO:0080090 311 0.095
Human
cellular aromatic compound metabolic process GO:0006725 295 0.090
Human
transcription dna templated GO:0006351 181 0.090
biosynthetic process GO:0009058 294 0.077
heterocycle biosynthetic process GO:0018130 215 0.075
alternative mrna splicing via spliceosome GO:0000380 1 0.073
Human
regulation of macromolecule biosynthetic process GO:0010556 225 0.072
cell morphogenesis GO:0000902 289 0.071
regulation of biological quality GO:0065008 263 0.070
female sex differentiation GO:0046660 4 0.070
signal transduction GO:0007165 455 0.070
macromolecule biosynthetic process GO:0009059 227 0.068
chordate embryonic development GO:0043009 271 0.067
regulation of gene expression GO:0010468 265 0.065
Human
organic cyclic compound biosynthetic process GO:1901362 223 0.065
positive regulation of rna metabolic process GO:0051254 59 0.063
eye development GO:0001654 277 0.063
stem cell proliferation GO:0072089 4 0.063
response to uv GO:0009411 3 0.061
embryo development ending in birth or egg hatching GO:0009792 271 0.059
somite development GO:0061053 96 0.058
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.056
regulation of biosynthetic process GO:0009889 250 0.056
homeostatic process GO:0042592 142 0.054
aromatic compound biosynthetic process GO:0019438 217 0.053
rna biosynthetic process GO:0032774 181 0.053
stem cell division GO:0017145 1 0.051
nucleobase containing compound biosynthetic process GO:0034654 205 0.051
immune system process GO:0002376 241 0.049
central nervous system development GO:0007417 387 0.049
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.048
positive regulation of apoptotic signaling pathway GO:2001235 1 0.048
nucleic acid templated transcription GO:0097659 181 0.047
transcription from rna polymerase ii promoter GO:0006366 80 0.047
anterior posterior pattern specification GO:0009952 152 0.046
regulation of developmental process GO:0050793 247 0.046
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.045
regulation of cellular biosynthetic process GO:0031326 245 0.045
regulation of anterior head development GO:2000742 2 0.044
generation of neurons GO:0048699 385 0.043
regulation of organ growth GO:0046620 3 0.042
regulation of cell activation GO:0050865 1 0.042
cell surface receptor signaling pathway GO:0007166 325 0.041
organic substance biosynthetic process GO:1901576 289 0.041
positive regulation of neuron apoptotic process GO:0043525 1 0.041
locomotion GO:0040011 313 0.041
development of primary female sexual characteristics GO:0046545 4 0.041
regulation of multicellular organism growth GO:0040014 4 0.041
single organism metabolic process GO:0044710 217 0.041
cellular macromolecule metabolic process GO:0044260 391 0.040
Human
positive regulation of cellular metabolic process GO:0031325 94 0.040
regulation of cellular metabolic process GO:0031323 320 0.039
Human
regulation of metabolic process GO:0019222 359 0.039
Human
protein metabolic process GO:0019538 183 0.038
maintenance of location GO:0051235 4 0.038
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.038
double strand break repair GO:0006302 3 0.038
organelle organization GO:0006996 227 0.036
positive regulation of transcription dna templated GO:0045893 57 0.036
spliceosomal complex assembly GO:0000245 1 0.036
regulation of cell shape GO:0008360 1 0.036
regulation of cell morphogenesis GO:0022604 42 0.035
positive regulation of cellular component biogenesis GO:0044089 3 0.035
single organism localization GO:1902578 225 0.035
regulation of signal transduction GO:0009966 225 0.034
stem cell maintenance GO:0019827 4 0.033
cellular biosynthetic process GO:0044249 286 0.033
programmed cell death GO:0012501 119 0.033
recombinational repair GO:0000725 1 0.032
response to organic substance GO:0010033 153 0.032
regionalization GO:0003002 274 0.032
determination of left right symmetry GO:0007368 179 0.032
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.031
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.030
positive regulation of jnk cascade GO:0046330 3 0.030
regulation of binding GO:0051098 3 0.030
sexual reproduction GO:0019953 36 0.030
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.030
Human
death GO:0016265 121 0.030
somitogenesis GO:0001756 87 0.030
lipid homeostasis GO:0055088 3 0.030
proteasomal protein catabolic process GO:0010498 2 0.029
growth GO:0040007 174 0.029
regulation of mrna splicing via spliceosome GO:0048024 3 0.029
Human
regulation of synapse organization GO:0050807 3 0.029
developmental growth GO:0048589 166 0.029
positive regulation of synapse assembly GO:0051965 1 0.029
cell projection organization GO:0030030 284 0.028
morphogenesis of an epithelium GO:0002009 333 0.028
response to stress GO:0006950 263 0.027
convergent extension GO:0060026 118 0.027
positive regulation of transport GO:0051050 2 0.027
regulation of circadian rhythm GO:0042752 4 0.027
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.027
negative regulation of cellular process GO:0048523 283 0.026
double strand break repair via homologous recombination GO:0000724 1 0.026
regulation of dna replication GO:0006275 3 0.026
gland development GO:0048732 143 0.026
regulation of multicellular organismal process GO:0051239 277 0.026
adult behavior GO:0030534 2 0.025
multicellular organism growth GO:0035264 4 0.025
meiotic nuclear division GO:0007126 4 0.025
negative regulation of metabolic process GO:0009892 86 0.025
cell morphogenesis involved in differentiation GO:0000904 195 0.025
forebrain cell migration GO:0021885 1 0.024
blood vessel development GO:0001568 246 0.024
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.024
carboxylic acid metabolic process GO:0019752 22 0.024
regulation of response to oxidative stress GO:1902882 2 0.024
embryonic hemopoiesis GO:0035162 53 0.024
embryonic pattern specification GO:0009880 44 0.024
compound eye development GO:0048749 2 0.024
embryonic organ development GO:0048568 381 0.023
regulation of cell communication GO:0010646 232 0.023
negative regulation of rna metabolic process GO:0051253 48 0.023
modification dependent protein catabolic process GO:0019941 3 0.023
negative regulation of cell differentiation GO:0045596 46 0.023
female gonad development GO:0008585 4 0.023
negative regulation of macromolecule metabolic process GO:0010605 76 0.023
digestive tract development GO:0048565 265 0.023
regulation of purine nucleotide catabolic process GO:0033121 2 0.022
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.022
neuroblast proliferation GO:0007405 2 0.022
intracellular mrna localization GO:0008298 1 0.022
phagocytosis GO:0006909 3 0.022
establishment of localization GO:0051234 244 0.022
triglyceride homeostasis GO:0070328 2 0.022
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.021
positive regulation of signal transduction GO:0009967 56 0.021
positive regulation of macromolecule metabolic process GO:0010604 93 0.021
positive regulation of rna biosynthetic process GO:1902680 57 0.021
response to biotic stimulus GO:0009607 97 0.021
oocyte anterior posterior axis specification GO:0007314 4 0.021
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.021
neural tube patterning GO:0021532 33 0.020
tube morphogenesis GO:0035239 349 0.020
regulation of synapse assembly GO:0051963 3 0.020
small molecule metabolic process GO:0044281 77 0.020
endothelial cell fate commitment GO:0060839 3 0.020
cellular amino acid metabolic process GO:0006520 7 0.020
positive regulation of epithelial cell proliferation GO:0050679 1 0.020
b cell activation GO:0042113 2 0.020
regulation of mrna processing GO:0050684 3 0.020
Human
regulation of cell differentiation GO:0045595 142 0.019
modification dependent macromolecule catabolic process GO:0043632 3 0.019
positive regulation of response to stimulus GO:0048584 80 0.019
dorsal ventral pattern formation GO:0009953 125 0.019
myeloid cell differentiation GO:0030099 86 0.019
regulation of growth GO:0040008 42 0.019
positive regulation of protein complex assembly GO:0031334 2 0.019
regulation of response to stimulus GO:0048583 269 0.019
acylglycerol homeostasis GO:0055090 2 0.019
cellular response to chemical stimulus GO:0070887 157 0.018
positive regulation of nucleic acid templated transcription GO:1903508 57 0.018
transport GO:0006810 220 0.018
response to abiotic stimulus GO:0009628 122 0.018
regulation of nucleoside metabolic process GO:0009118 2 0.018
negative regulation of gene expression GO:0010629 65 0.018
lipid storage GO:0019915 1 0.018
endodermal cell fate determination GO:0007493 2 0.018
positive regulation of cell activation GO:0050867 1 0.018
cell death in response to oxidative stress GO:0036473 2 0.018
cellular response to extracellular stimulus GO:0031668 2 0.018
microtubule based process GO:0007017 60 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.018
regulation of reproductive process GO:2000241 4 0.018
mononuclear cell proliferation GO:0032943 1 0.018
neuron projection development GO:0031175 180 0.018
negative regulation of dna replication GO:0008156 2 0.018
regulation of rna splicing GO:0043484 8 0.017
Human
embryonic organ morphogenesis GO:0048562 274 0.017
embryonic limb morphogenesis GO:0030326 2 0.017
chemical homeostasis GO:0048878 49 0.017
reciprocal dna recombination GO:0035825 1 0.017
cortical cytoskeleton organization GO:0030865 1 0.017
carbohydrate biosynthetic process GO:0016051 1 0.017
neuron differentiation GO:0030182 353 0.017
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.017
erythrocyte homeostasis GO:0034101 55 0.017
positive regulation of cellular catabolic process GO:0031331 3 0.017
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.017
intracellular signal transduction GO:0035556 85 0.017
positive regulation of nucleoside metabolic process GO:0045979 1 0.016
primitive hemopoiesis GO:0060215 27 0.016
cell matrix adhesion GO:0007160 4 0.016
cardiac muscle tissue morphogenesis GO:0055008 7 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
regulation of stem cell proliferation GO:0072091 2 0.016
central nervous system neuron differentiation GO:0021953 74 0.016
cell part morphogenesis GO:0032990 246 0.016
cellular response to radiation GO:0071478 4 0.016
multi organism reproductive process GO:0044703 36 0.016
regulation of developmental growth GO:0048638 38 0.016
response to drug GO:0042493 3 0.016
regulation of neural precursor cell proliferation GO:2000177 3 0.016
regulation of molecular function GO:0065009 70 0.016
cellular carbohydrate metabolic process GO:0044262 4 0.016
ubiquitin dependent protein catabolic process GO:0006511 3 0.016
odontogenesis of dentin containing tooth GO:0042475 1 0.016
pole plasm assembly GO:0007315 4 0.015
digestive system development GO:0055123 289 0.015
negative regulation of developmental process GO:0051093 65 0.015
single organism biosynthetic process GO:0044711 71 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.015
single organism organelle organization GO:1902589 199 0.015
positive regulation of chromatin modification GO:1903310 1 0.015
regulation of gene expression epigenetic GO:0040029 11 0.015
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.015
regulation of multicellular organismal development GO:2000026 223 0.015
brain development GO:0007420 293 0.015
mitochondrion organization GO:0007005 4 0.015
aorta development GO:0035904 4 0.015
muscle structure development GO:0061061 196 0.015
neuron neuron synaptic transmission GO:0007270 1 0.015
positive regulation of ras protein signal transduction GO:0046579 1 0.015
cellular amine metabolic process GO:0044106 2 0.015
muscle organ development GO:0007517 101 0.015
entrainment of circadian clock GO:0009649 2 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.014
localization of cell GO:0051674 244 0.014
cellular ketone metabolic process GO:0042180 11 0.014
response to endogenous stimulus GO:0009719 83 0.014
organic acid metabolic process GO:0006082 31 0.014
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.014
positive regulation of cell communication GO:0010647 56 0.014
meiosis i GO:0007127 1 0.014
protein acylation GO:0043543 3 0.014
erythrocyte maturation GO:0043249 8 0.014
cell cycle arrest GO:0007050 1 0.014
cellular response to external stimulus GO:0071496 2 0.014
erythrocyte differentiation GO:0030218 54 0.014
cell death GO:0008219 121 0.014
mrna metabolic process GO:0016071 20 0.014
Human
organonitrogen compound metabolic process GO:1901564 74 0.014
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
peptidyl lysine acetylation GO:0018394 2 0.013
secondary metabolic process GO:0019748 3 0.013
regulation of signaling GO:0023051 235 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.013
cellular response to dna damage stimulus GO:0006974 24 0.013
purine nucleoside monophosphate catabolic process GO:0009128 4 0.013
cytoskeleton dependent cytokinesis GO:0061640 3 0.013
regulation of response to biotic stimulus GO:0002831 2 0.013
g1 s transition of mitotic cell cycle GO:0000082 1 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.013
lymphocyte differentiation GO:0030098 9 0.013
positive regulation of cell division GO:0051781 2 0.013
positive regulation of histone modification GO:0031058 1 0.013
neuron projection morphogenesis GO:0048812 161 0.013
neural precursor cell proliferation GO:0061351 20 0.013
maternal determination of anterior posterior axis embryo GO:0008358 4 0.013
cellular response to nutrient levels GO:0031669 2 0.013
3 utr mediated mrna stabilization GO:0070935 3 0.013
negative regulation of biological process GO:0048519 304 0.013
regulation of protein binding GO:0043393 3 0.013
regulation of photoreceptor cell differentiation GO:0046532 2 0.013
positive regulation of catabolic process GO:0009896 4 0.013
reproductive process GO:0022414 40 0.013
cytokinetic process GO:0032506 2 0.013
pharyngeal muscle development GO:0043282 4 0.013
regulation of growth rate GO:0040009 1 0.013
negative regulation of leukocyte differentiation GO:1902106 1 0.012
multi organism process GO:0051704 134 0.012
regulation of cytoplasmic transport GO:1903649 4 0.012
neurotransmitter transport GO:0006836 2 0.012
cellular response to organic substance GO:0071310 105 0.012
positive regulation of cellular biosynthetic process GO:0031328 68 0.012
myeloid cell homeostasis GO:0002262 56 0.012
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.012
anterior head development GO:0097065 2 0.012
head development GO:0060322 303 0.012
amine metabolic process GO:0009308 2 0.012
negative regulation of rna biosynthetic process GO:1902679 45 0.012
protein import GO:0017038 3 0.012
aging GO:0007568 2 0.012
response to hormone GO:0009725 48 0.012
positive regulation of neuron death GO:1901216 1 0.012
negative regulation of multi organism process GO:0043901 3 0.012
smooth muscle tissue development GO:0048745 1 0.012
response to wounding GO:0009611 116 0.012
protein localization to nucleus GO:0034504 3 0.012
multicellular organismal homeostasis GO:0048871 29 0.012
response to lipid GO:0033993 60 0.012
nuclear import GO:0051170 3 0.012
liver development GO:0001889 96 0.012
rna modification GO:0009451 2 0.012
Human
signal transduction in absence of ligand GO:0038034 1 0.011
negative regulation of response to stimulus GO:0048585 104 0.011
cell migration GO:0016477 237 0.011
positive regulation of muscle cell differentiation GO:0051149 1 0.011
skeletal system development GO:0001501 181 0.011
regulation of cellular response to oxidative stress GO:1900407 2 0.011
nuclear body organization GO:0030575 2 0.011
positive regulation of biosynthetic process GO:0009891 68 0.011
tissue remodeling GO:0048771 4 0.011
developmental growth involved in morphogenesis GO:0060560 86 0.011
phagocytosis engulfment GO:0006911 1 0.011
regulation of production of molecular mediator of immune response GO:0002700 1 0.011
cellular response to endogenous stimulus GO:0071495 68 0.011
negative regulation of rna splicing GO:0033119 1 0.011
developmental maturation GO:0021700 34 0.011
methylation GO:0032259 22 0.011
Human
homeostasis of number of cells within a tissue GO:0048873 4 0.011
protein secretion GO:0009306 1 0.011
modification of morphology or physiology of other organism GO:0035821 4 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
multicellular organismal reproductive process GO:0048609 35 0.011
gtp catabolic process GO:0006184 2 0.011
hepaticobiliary system development GO:0061008 98 0.011
regulation of stem cell differentiation GO:2000736 4 0.011
small gtpase mediated signal transduction GO:0007264 8 0.011
striated muscle tissue development GO:0014706 110 0.011
striated muscle cell differentiation GO:0051146 129 0.011
homeostasis of number of cells GO:0048872 62 0.011
rostrocaudal neural tube patterning GO:0021903 29 0.011
regulation of cell substrate adhesion GO:0010810 1 0.011
internal peptidyl lysine acetylation GO:0018393 2 0.011
cytokinesis GO:0000910 3 0.011
cell projection morphogenesis GO:0048858 244 0.010
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.010
muscle cell differentiation GO:0042692 139 0.010
response to external stimulus GO:0009605 264 0.010
somatic stem cell maintenance GO:0035019 1 0.010
regulation of dna templated transcription elongation GO:0032784 3 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.010
oxoacid metabolic process GO:0043436 31 0.010
developmental cell growth GO:0048588 52 0.010
guanosine containing compound metabolic process GO:1901068 4 0.010
maintenance of gastrointestinal epithelium GO:0030277 7 0.010
negative regulation of i kappab kinase nf kappab signaling GO:0043124 1 0.010
regulation of anatomical structure morphogenesis GO:0022603 130 0.010
apoptotic process GO:0006915 116 0.010
sex determination GO:0007530 1 0.010
protein dephosphorylation GO:0006470 3 0.010
digestive system process GO:0022600 9 0.010
b cell differentiation GO:0030183 1 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.010

wtap disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.064
nervous system disease DOID:863 0 0.017
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
physical disorder DOID:0080015 0 0.014
musculoskeletal system disease DOID:17 0 0.012
organ system cancer DOID:0050686 0 0.012
thoracic cancer DOID:5093 0 0.011
musculoskeletal system cancer DOID:0060100 0 0.010