Danio rerio

0 known processes

wu:fb17g07

wu:fb17g07

wu:fb17g07 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
central nervous system development GO:0007417 387 0.389
nuclear export GO:0051168 1 0.174
larval development GO:0002164 2 0.153
organic substance biosynthetic process GO:1901576 289 0.142
regulation of apoptotic process GO:0042981 98 0.133
lipid storage GO:0019915 1 0.120
regulation of mrna splicing via spliceosome GO:0048024 3 0.118
convergent extension involved in organogenesis GO:0060029 10 0.105
cellular nitrogen compound biosynthetic process GO:0044271 218 0.103
startle response GO:0001964 4 0.102
positive regulation of secretion GO:0051047 1 0.097
cellular macromolecule biosynthetic process GO:0034645 224 0.090
negative regulation of cellular process GO:0048523 283 0.089
positive regulation of transport GO:0051050 2 0.087
nuclear transport GO:0051169 4 0.087
apoptotic process GO:0006915 116 0.086
regulation of anatomical structure morphogenesis GO:0022603 130 0.086
rna export from nucleus GO:0006405 1 0.080
maintenance of location GO:0051235 4 0.079
cellular component morphogenesis GO:0032989 336 0.078
brain development GO:0007420 293 0.074
regulation of translational initiation GO:0006446 1 0.071
heterocycle biosynthetic process GO:0018130 215 0.069
regulation of cell differentiation GO:0045595 142 0.068
negative regulation of biological process GO:0048519 304 0.067
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.067
lymphatic endothelial cell differentiation GO:0060836 1 0.066
cell differentiation in spinal cord GO:0021515 40 0.065
death GO:0016265 121 0.064
cell projection organization GO:0030030 284 0.060
positive regulation of cellular component biogenesis GO:0044089 3 0.059
nucleotide metabolic process GO:0009117 28 0.058
nucleic acid templated transcription GO:0097659 181 0.058
alternative mrna splicing via spliceosome GO:0000380 1 0.058
establishment of localization GO:0051234 244 0.057
biosynthetic process GO:0009058 294 0.057
spinal cord motor neuron differentiation GO:0021522 26 0.055
programmed cell death GO:0012501 119 0.054
translational initiation GO:0006413 3 0.054
cellular component movement GO:0006928 335 0.054
organelle organization GO:0006996 227 0.053
positive regulation of translation GO:0045727 1 0.051
dorsal ventral pattern formation GO:0009953 125 0.051
glucose homeostasis GO:0042593 1 0.050
head development GO:0060322 303 0.050
generation of neurons GO:0048699 385 0.049
response to external stimulus GO:0009605 264 0.049
organic cyclic compound biosynthetic process GO:1901362 223 0.049
regulation of cell death GO:0010941 103 0.049
positive regulation of cell cycle GO:0045787 3 0.048
lymphatic endothelial cell fate commitment GO:0060838 1 0.048
gtp metabolic process GO:0046039 4 0.047
regulation of mrna processing GO:0050684 3 0.047
rna stabilization GO:0043489 4 0.046
rna transport GO:0050658 2 0.046
positive regulation of secretion by cell GO:1903532 1 0.044
cranial nerve morphogenesis GO:0021602 15 0.044
blood vessel morphogenesis GO:0048514 216 0.044
regulation of biological quality GO:0065008 263 0.044
regulation of response to stimulus GO:0048583 269 0.043
cardioblast migration to the midline involved in heart field formation GO:0060975 7 0.043
response to organic substance GO:0010033 153 0.042
regulation of programmed cell death GO:0043067 101 0.042
forebrain development GO:0030900 96 0.041
negative regulation of apoptotic process GO:0043066 55 0.041
signal transduction GO:0007165 455 0.041
purine nucleoside monophosphate catabolic process GO:0009128 4 0.040
negative regulation of cell death GO:0060548 60 0.040
regulation of transcription dna templated GO:0006355 213 0.040
regulation of rna metabolic process GO:0051252 224 0.039
positive regulation of cellular process GO:0048522 201 0.039
regulation of circadian rhythm GO:0042752 4 0.039
establishment of rna localization GO:0051236 3 0.039
nucleocytoplasmic transport GO:0006913 4 0.038
negative regulation of protein complex assembly GO:0031333 1 0.038
regulation of macromolecule metabolic process GO:0060255 317 0.037
guanosine containing compound metabolic process GO:1901068 4 0.037
regulation of myelination GO:0031641 1 0.036
blood vessel development GO:0001568 246 0.036
oxoacid metabolic process GO:0043436 31 0.036
regulation of localization GO:0032879 104 0.035
ameboidal type cell migration GO:0001667 143 0.035
cell death GO:0008219 121 0.035
response to chemical GO:0042221 320 0.035
phosphate containing compound metabolic process GO:0006796 108 0.034
growth GO:0040007 174 0.034
stem cell maintenance GO:0019827 4 0.034
gene expression GO:0010467 252 0.034
macromolecule biosynthetic process GO:0009059 227 0.033
germ line stem cell maintenance GO:0030718 2 0.033
aging GO:0007568 2 0.032
brain morphogenesis GO:0048854 18 0.032
regulation of signaling GO:0023051 235 0.032
protein acetylation GO:0006473 2 0.031
spinal cord development GO:0021510 46 0.031
regulation of developmental process GO:0050793 247 0.031
negative regulation of programmed cell death GO:0043069 58 0.031
positive regulation of multi organism process GO:0043902 3 0.031
response to hexose GO:0009746 3 0.031
rna metabolic process GO:0016070 219 0.030
nucleic acid transport GO:0050657 2 0.029
3 utr mediated mrna stabilization GO:0070935 3 0.028
regulation of protein complex assembly GO:0043254 3 0.028
regulation of ion transmembrane transporter activity GO:0032412 2 0.028
regulation of reproductive process GO:2000241 4 0.028
regulation of nucleocytoplasmic transport GO:0046822 2 0.027
stem cell differentiation GO:0048863 117 0.027
nucleoside phosphate biosynthetic process GO:1901293 21 0.027
nucleobase containing compound metabolic process GO:0006139 274 0.027
regionalization GO:0003002 274 0.026
positive regulation of carbohydrate metabolic process GO:0045913 1 0.026
regulation of sequestering of calcium ion GO:0051282 4 0.026
hormone secretion GO:0046879 2 0.026
vasculature development GO:0001944 278 0.026
rna localization GO:0006403 4 0.026
locomotion GO:0040011 313 0.026
regulation of multicellular organismal development GO:2000026 223 0.026
wnt signaling pathway GO:0016055 80 0.025
regulation of cellular amino acid metabolic process GO:0006521 0 0.025
spermatid differentiation GO:0048515 2 0.024
neuron development GO:0048666 262 0.024
regulation of locomotion GO:0040012 55 0.024
embryonic organ development GO:0048568 381 0.024
production of molecular mediator of immune response GO:0002440 2 0.024
glial cell migration GO:0008347 3 0.023
convergent extension GO:0060026 118 0.023
nuclear migration GO:0007097 3 0.023
cell migration to the midline involved in heart development GO:0003318 12 0.023
organic cyclic compound metabolic process GO:1901360 301 0.023
carbohydrate derivative metabolic process GO:1901135 61 0.023
neuron differentiation GO:0030182 353 0.023
multi organism process GO:0051704 134 0.023
single organism localization GO:1902578 225 0.023
cell morphogenesis GO:0000902 289 0.023
protein polymerization GO:0051258 4 0.023
cellular response to biotic stimulus GO:0071216 3 0.023
cytokinesis GO:0000910 3 0.023
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.023
synaptic growth at neuromuscular junction GO:0051124 2 0.022
regulation of calcium ion dependent exocytosis GO:0017158 1 0.022
regulation of production of molecular mediator of immune response GO:0002700 1 0.022
multicellular organism growth GO:0035264 4 0.022
organonitrogen compound metabolic process GO:1901564 74 0.022
epithelial cell differentiation GO:0030855 116 0.022
regulation of protein transport GO:0051223 3 0.022
nucleobase containing compound biosynthetic process GO:0034654 205 0.022
muscle system process GO:0003012 20 0.022
amine metabolic process GO:0009308 2 0.021
cellular macromolecule metabolic process GO:0044260 391 0.021
nucleotide biosynthetic process GO:0009165 21 0.021
regulation of smoothened signaling pathway GO:0008589 18 0.021
ventral spinal cord development GO:0021517 35 0.021
regulation of cell activation GO:0050865 1 0.021
regulation of ion transport GO:0043269 22 0.021
energy reserve metabolic process GO:0006112 2 0.021
rna biosynthetic process GO:0032774 181 0.021
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.020
carboxylic acid metabolic process GO:0019752 22 0.020
nitrogen compound metabolic process GO:0006807 319 0.020
phagocytosis GO:0006909 3 0.020
mitotic dna integrity checkpoint GO:0044774 4 0.020
positive regulation of response to stimulus GO:0048584 80 0.020
protein import GO:0017038 3 0.020
activation of mapk activity GO:0000187 3 0.020
cellular protein metabolic process GO:0044267 129 0.020
somatic stem cell maintenance GO:0035019 1 0.020
positive regulation of cellular amine metabolic process GO:0033240 0 0.019
camera type eye development GO:0043010 222 0.019
midbrain development GO:0030901 28 0.019
mitotic cytokinesis GO:0000281 3 0.019
protein modification process GO:0036211 100 0.019
protein acylation GO:0043543 3 0.019
cellular biosynthetic process GO:0044249 286 0.019
sensory organ development GO:0007423 393 0.019
compound eye development GO:0048749 2 0.019
optic nerve formation GO:0021634 6 0.019
response to monosaccharide GO:0034284 3 0.018
lamellipodium assembly GO:0030032 1 0.018
female gonad development GO:0008585 4 0.018
phosphorus metabolic process GO:0006793 109 0.018
response to glucocorticoid GO:0051384 1 0.018
epiboly GO:0090504 41 0.018
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 10 0.018
cellular aromatic compound metabolic process GO:0006725 295 0.017
establishment of localization in cell GO:0051649 77 0.017
muscle structure development GO:0061061 196 0.017
nucleic acid metabolic process GO:0090304 244 0.017
response to uv GO:0009411 3 0.017
spermatid development GO:0007286 2 0.017
mrna splicing via spliceosome GO:0000398 10 0.017
mrna stabilization GO:0048255 4 0.017
cellular amine metabolic process GO:0044106 2 0.017
dopaminergic neuron differentiation GO:0071542 14 0.017
aromatic compound biosynthetic process GO:0019438 217 0.017
response to stress GO:0006950 263 0.017
cellular protein modification process GO:0006464 100 0.017
regulation of cytoplasmic transport GO:1903649 4 0.017
single organism organelle organization GO:1902589 199 0.017
microtubule organizing center organization GO:0031023 1 0.017
single organism metabolic process GO:0044710 217 0.017
transcription from rna polymerase iii promoter GO:0006383 1 0.017
endothelial cell fate commitment GO:0060839 3 0.017
astrocyte differentiation GO:0048708 1 0.017
heterocycle metabolic process GO:0046483 290 0.017
transport GO:0006810 220 0.017
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.017
long chain fatty acid transport GO:0015909 1 0.016
cellular component assembly GO:0022607 170 0.016
negative regulation of leukocyte differentiation GO:1902106 1 0.016
single organism reproductive process GO:0044702 40 0.016
cellular amide metabolic process GO:0043603 4 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.016
response to carbohydrate GO:0009743 3 0.016
axon guidance GO:0007411 86 0.016
b cell activation GO:0042113 2 0.016
regulation of metabolic process GO:0019222 359 0.016
regulation of synapse organization GO:0050807 3 0.016
negative regulation of multicellular organismal process GO:0051241 69 0.016
atp catabolic process GO:0006200 4 0.016
eye development GO:0001654 277 0.016
macromolecule modification GO:0043412 111 0.016
positive regulation of myeloid cell differentiation GO:0045639 2 0.016
regulation of neural precursor cell proliferation GO:2000177 3 0.016
multicellular organism reproduction GO:0032504 35 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.015
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.015
somitogenesis GO:0001756 87 0.015
cognition GO:0050890 1 0.015
centrosome organization GO:0051297 1 0.015
smoothened signaling pathway GO:0007224 30 0.015
internal peptidyl lysine acetylation GO:0018393 2 0.015
skeletal system development GO:0001501 181 0.015
urogenital system development GO:0001655 97 0.015
morphogenesis of an epithelium GO:0002009 333 0.015
positive regulation of apoptotic signaling pathway GO:2001235 1 0.015
positive regulation of biological process GO:0048518 253 0.015
regulation of cell communication GO:0010646 232 0.015
exocytosis GO:0006887 1 0.015
developmental growth GO:0048589 166 0.015
determination of bilateral symmetry GO:0009855 204 0.015
optic nerve morphogenesis GO:0021631 6 0.015
negative regulation of ras protein signal transduction GO:0046580 1 0.015
mononuclear cell proliferation GO:0032943 1 0.015
single organism transport GO:0044765 206 0.015
cellular component biogenesis GO:0044085 178 0.014
regulation of rna biosynthetic process GO:2001141 213 0.014
regulation of metal ion transport GO:0010959 4 0.014
inner ear receptor cell development GO:0060119 20 0.014
positive regulation of cytokine production GO:0001819 2 0.014
myeloid cell development GO:0061515 32 0.014
cell migration GO:0016477 237 0.014
regulation of cellular biosynthetic process GO:0031326 245 0.014
regulation of gene expression epigenetic GO:0040029 11 0.014
regulation of nitrogen compound metabolic process GO:0051171 251 0.014
cellular response to topologically incorrect protein GO:0035967 2 0.014
retina development in camera type eye GO:0060041 146 0.014
nerve development GO:0021675 45 0.014
lymphangiogenesis GO:0001946 25 0.014
nucleobase containing compound transport GO:0015931 2 0.014
neuron projection extension GO:1990138 45 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.014
ribonucleoside monophosphate catabolic process GO:0009158 4 0.014
peptidyl lysine acetylation GO:0018394 2 0.014
response to abiotic stimulus GO:0009628 122 0.014
regulation of neuron differentiation GO:0045664 56 0.014
regulation of primary metabolic process GO:0080090 311 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.014
regulation of nervous system development GO:0051960 90 0.014
regulation of protein targeting GO:1903533 2 0.014
regulation of cellular component organization GO:0051128 86 0.013
peptide transport GO:0015833 1 0.013
cortical cytoskeleton organization GO:0030865 1 0.013
neuron projection guidance GO:0097485 86 0.013
somatic cell dna recombination GO:0016444 1 0.013
negative regulation of nuclear division GO:0051784 3 0.013
positive regulation of immune effector process GO:0002699 3 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.013
spinal cord association neuron differentiation GO:0021527 1 0.013
antimicrobial humoral response GO:0019730 2 0.013
lateral inhibition GO:0046331 1 0.013
positive regulation of jnk cascade GO:0046330 3 0.013
anterior posterior pattern specification GO:0009952 152 0.013
regulation of mrna stability GO:0043488 4 0.013
guanosine containing compound catabolic process GO:1901069 2 0.013
regulation of binding GO:0051098 3 0.013
photoreceptor cell fate commitment GO:0046552 1 0.013
fin regeneration GO:0031101 51 0.013
syncytium formation by plasma membrane fusion GO:0000768 12 0.013
mesoderm development GO:0007498 88 0.013
mitotic dna damage checkpoint GO:0044773 4 0.013
regulation of neurogenesis GO:0050767 87 0.013
myotube differentiation GO:0014902 45 0.013
regulation of signal transduction GO:0009966 225 0.013
regulation of synapse assembly GO:0051963 3 0.013
negative regulation of synapse assembly GO:0051964 2 0.013
protein metabolic process GO:0019538 183 0.012
fatty acid transport GO:0015908 1 0.012
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.012
hemopoiesis GO:0030097 183 0.012
cellular nitrogen compound metabolic process GO:0034641 290 0.012
response to nitrogen compound GO:1901698 19 0.012
cytoskeleton organization GO:0007010 96 0.012
cartilage development GO:0051216 96 0.012
regulation of cellular component movement GO:0051270 55 0.012
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.012
cellular amino acid metabolic process GO:0006520 7 0.012
regulation of nucleic acid templated transcription GO:1903506 213 0.012
cellular response to stress GO:0033554 62 0.012
regulation of establishment of protein localization GO:0070201 4 0.012
negative regulation of developmental process GO:0051093 65 0.012
specification of symmetry GO:0009799 204 0.012
axon extension GO:0048675 45 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.012
epithelial cell morphogenesis GO:0003382 2 0.012
regulation of cell morphogenesis GO:0022604 42 0.012
mrna metabolic process GO:0016071 20 0.012
negative regulation of cell projection organization GO:0031345 9 0.012
regulation of protein ubiquitination GO:0031396 3 0.012
regulation of cellular metabolic process GO:0031323 320 0.012
response to corticosteroid GO:0031960 1 0.012
cardioblast migration GO:0003260 7 0.012
erythrocyte maturation GO:0043249 8 0.012
cranial nerve development GO:0021545 42 0.012
rhythmic process GO:0048511 21 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
cell migration involved in heart formation GO:0060974 10 0.011
auditory receptor cell morphogenesis GO:0002093 4 0.011
system process GO:0003008 185 0.011
angiogenesis GO:0001525 158 0.011
organic acid metabolic process GO:0006082 31 0.011
regulation of cellular ketone metabolic process GO:0010565 7 0.011
reproduction GO:0000003 40 0.011
positive regulation of cell communication GO:0010647 56 0.011
protein localization to nucleus GO:0034504 3 0.011
regulation of rna splicing GO:0043484 8 0.011
cardiac atrium morphogenesis GO:0003209 2 0.011
negative regulation of response to stimulus GO:0048585 104 0.011
regulation of cell shape GO:0008360 1 0.011
cell morphogenesis involved in differentiation GO:0000904 195 0.011
intracellular transport GO:0046907 32 0.011
ribonucleotide metabolic process GO:0009259 27 0.011
cellular ketone metabolic process GO:0042180 11 0.011
retina morphogenesis in camera type eye GO:0060042 79 0.011
negative regulation of rna splicing GO:0033119 1 0.011
polarized epithelial cell differentiation GO:0030859 4 0.011
digestive system development GO:0055123 289 0.011
actin filament polymerization GO:0030041 2 0.011
rna splicing GO:0008380 16 0.011
megakaryocyte differentiation GO:0030219 1 0.011
morphogenesis of an epithelial sheet GO:0002011 49 0.011
extrinsic apoptotic signaling pathway GO:0097191 3 0.011
purine containing compound metabolic process GO:0072521 29 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
actin cytoskeleton organization GO:0030036 63 0.011
pronuclear migration GO:0035046 1 0.011
gtp catabolic process GO:0006184 2 0.011
positive regulation of epithelial cell differentiation GO:0030858 2 0.010
negative chemotaxis GO:0050919 1 0.010
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.010
response to glucose GO:0009749 3 0.010
secondary metabolic process GO:0019748 3 0.010
spindle assembly involved in mitosis GO:0090307 1 0.010
response to external biotic stimulus GO:0043207 97 0.010
metencephalon development GO:0022037 27 0.010
immune response GO:0006955 28 0.010
pigment cell differentiation GO:0050931 38 0.010
endodermal cell fate determination GO:0007493 2 0.010
cell proliferation in forebrain GO:0021846 3 0.010
negative regulation of myeloid cell differentiation GO:0045638 1 0.010
cell part morphogenesis GO:0032990 246 0.010
regulation of dendrite morphogenesis GO:0048814 3 0.010
positive regulation of catabolic process GO:0009896 4 0.010
homeostatic process GO:0042592 142 0.010
muscle organ development GO:0007517 101 0.010
endothelium development GO:0003158 25 0.010
signal transduction in absence of ligand GO:0038034 1 0.010
regulation of calcium ion transport GO:0051924 2 0.010
positive regulation of signaling GO:0023056 56 0.010

wu:fb17g07 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
physical disorder DOID:0080015 0 0.047
congenital nervous system abnormality DOID:2490 0 0.033
lissencephaly DOID:0050453 0 0.020
disease of metabolism DOID:0014667 0 0.017
musculoskeletal system disease DOID:17 0 0.014
disease of anatomical entity DOID:7 0 0.014