Danio rerio

0 known processes

wu:fb58e05

wu:fb58e05

(Aliases: fb58e05)

wu:fb58e05 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of mrna processing GO:0050684 3 0.518
regulation of mrna splicing via spliceosome GO:0048024 3 0.313
cellular macromolecule metabolic process GO:0044260 391 0.301
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.296
rna polyadenylation GO:0043631 2 0.231
organic cyclic compound metabolic process GO:1901360 301 0.227
meiotic cell cycle process GO:1903046 3 0.207
rna metabolic process GO:0016070 219 0.189
regulation of biological quality GO:0065008 263 0.172
meiotic nuclear division GO:0007126 4 0.168
regulation of metabolic process GO:0019222 359 0.167
nucleobase containing compound metabolic process GO:0006139 274 0.159
apoptotic process GO:0006915 116 0.156
death GO:0016265 121 0.155
regulation of response to stimulus GO:0048583 269 0.153
head development GO:0060322 303 0.150
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 4 0.146
locomotion GO:0040011 313 0.139
regulation of meiotic cell cycle GO:0051445 1 0.134
negative regulation of kinase activity GO:0033673 4 0.127
regulation of apoptotic process GO:0042981 98 0.127
negative regulation of protein kinase activity GO:0006469 4 0.121
regulation of catalytic activity GO:0050790 55 0.117
nuclear division GO:0000280 23 0.116
cell migration GO:0016477 237 0.114
cellular aromatic compound metabolic process GO:0006725 295 0.113
cellular nitrogen compound metabolic process GO:0034641 290 0.113
heterocycle metabolic process GO:0046483 290 0.113
hemopoiesis GO:0030097 183 0.112
cellular component movement GO:0006928 335 0.105
response to external stimulus GO:0009605 264 0.104
regulation of cell death GO:0010941 103 0.100
cell motility GO:0048870 244 0.097
cell death GO:0008219 121 0.089
organelle organization GO:0006996 227 0.088
nucleic acid templated transcription GO:0097659 181 0.086
cell cycle process GO:0022402 53 0.085
regulation of macromolecule metabolic process GO:0060255 317 0.085
amine metabolic process GO:0009308 2 0.085
programmed cell death GO:0012501 119 0.084
negative regulation of protein phosphorylation GO:0001933 4 0.081
homeostatic process GO:0042592 142 0.080
alternative mrna splicing via spliceosome GO:0000380 1 0.080
response to stress GO:0006950 263 0.079
single organism transport GO:0044765 206 0.075
cellular component assembly GO:0022607 170 0.074
sensory organ development GO:0007423 393 0.073
positive regulation of signal transduction GO:0009967 56 0.072
positive regulation of signaling GO:0023056 56 0.072
muscle structure development GO:0061061 196 0.071
mitotic cell cycle GO:0000278 64 0.069
larval development GO:0002164 2 0.068
generation of neurons GO:0048699 385 0.067
regulation of programmed cell death GO:0043067 101 0.067
regulation of reproductive process GO:2000241 4 0.067
response to chemical GO:0042221 320 0.067
intracellular signal transduction GO:0035556 85 0.064
regulation of binding GO:0051098 3 0.064
gland development GO:0048732 143 0.063
mrna metabolic process GO:0016071 20 0.063
nucleic acid metabolic process GO:0090304 244 0.061
rna localization GO:0006403 4 0.061
rna splicing GO:0008380 16 0.061
negative regulation of cellular catabolic process GO:0031330 3 0.061
brain development GO:0007420 293 0.057
nucleocytoplasmic transport GO:0006913 4 0.057
negative regulation of biological process GO:0048519 304 0.056
cellular component biogenesis GO:0044085 178 0.056
protein modification process GO:0036211 100 0.055
protein localization to nucleus GO:0034504 3 0.054
regulation of cellular amino acid metabolic process GO:0006521 0 0.054
positive regulation of transport GO:0051050 2 0.054
digestive tract morphogenesis GO:0048546 231 0.053
meiotic chromosome segregation GO:0045132 3 0.053
positive regulation of cell communication GO:0010647 56 0.053
specification of symmetry GO:0009799 204 0.051
macromolecule modification GO:0043412 111 0.051
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 10 0.051
positive regulation of metabolic process GO:0009893 108 0.051
guanosine containing compound metabolic process GO:1901068 4 0.051
female meiotic division GO:0007143 2 0.051
regulation of primary metabolic process GO:0080090 311 0.050
embryonic organ development GO:0048568 381 0.050
gene expression GO:0010467 252 0.050
negative regulation of apoptotic process GO:0043066 55 0.050
spliceosomal complex assembly GO:0000245 1 0.049
regulation of multicellular organismal development GO:2000026 223 0.049
regulation of intracellular signal transduction GO:1902531 57 0.049
regulation of gene expression GO:0010468 265 0.049
aging GO:0007568 2 0.048
protein phosphorylation GO:0006468 47 0.047
regulation of signal transduction GO:0009966 225 0.047
negative regulation of cellular process GO:0048523 283 0.045
nucleobase containing compound biosynthetic process GO:0034654 205 0.045
nitrogen compound metabolic process GO:0006807 319 0.045
single organism localization GO:1902578 225 0.045
cellular component morphogenesis GO:0032989 336 0.045
negative regulation of map kinase activity GO:0043407 2 0.044
cellular amine metabolic process GO:0044106 2 0.044
modification dependent protein catabolic process GO:0019941 3 0.043
cell differentiation in spinal cord GO:0021515 40 0.043
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.043
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.043
cellular protein catabolic process GO:0044257 4 0.043
digestive system development GO:0055123 289 0.042
regulation of nucleic acid templated transcription GO:1903506 213 0.042
regulation of cytoplasmic transport GO:1903649 4 0.042
negative regulation of mrna splicing via spliceosome GO:0048025 1 0.042
nuclear transport GO:0051169 4 0.042
mitotic cell cycle process GO:1903047 48 0.041
chordate embryonic development GO:0043009 271 0.041
regulation of cellular metabolic process GO:0031323 320 0.041
rna splicing via transesterification reactions GO:0000375 10 0.040
embryo development ending in birth or egg hatching GO:0009792 271 0.040
positive regulation of response to stimulus GO:0048584 80 0.040
heart development GO:0007507 313 0.040
maintenance of location GO:0051235 4 0.040
cellular response to external stimulus GO:0071496 2 0.040
positive regulation of cellular process GO:0048522 201 0.039
regulation of cellular amine metabolic process GO:0033238 0 0.039
positive regulation of apoptotic process GO:0043065 29 0.039
localization of cell GO:0051674 244 0.039
cell proliferation GO:0008283 80 0.038
regulation of rna splicing GO:0043484 8 0.038
tube morphogenesis GO:0035239 349 0.038
cellular protein metabolic process GO:0044267 129 0.038
regulation of epithelial cell proliferation GO:0050678 3 0.037
positive regulation of cellular metabolic process GO:0031325 94 0.037
regulation of oocyte development GO:0060281 3 0.037
regulation of cellular ketone metabolic process GO:0010565 7 0.037
regionalization GO:0003002 274 0.036
regulation of intracellular protein transport GO:0033157 3 0.036
stem cell proliferation GO:0072089 4 0.036
negative regulation of myeloid cell differentiation GO:0045638 1 0.035
rna biosynthetic process GO:0032774 181 0.035
determination of bilateral symmetry GO:0009855 204 0.035
single organism organelle organization GO:1902589 199 0.035
ubiquitin dependent protein catabolic process GO:0006511 3 0.035
mesenchyme development GO:0060485 127 0.035
somitogenesis GO:0001756 87 0.035
negative regulation of rna splicing GO:0033119 1 0.035
regulation of protein metabolic process GO:0051246 56 0.035
regulation of rna biosynthetic process GO:2001141 213 0.034
gamete generation GO:0007276 33 0.034
regulation of molecular function GO:0065009 70 0.034
morphogenesis of an epithelium GO:0002009 333 0.034
nuclear export GO:0051168 1 0.034
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.034
microtubule based process GO:0007017 60 0.034
gtp metabolic process GO:0046039 4 0.034
modification dependent macromolecule catabolic process GO:0043632 3 0.033
negative regulation of leukocyte differentiation GO:1902106 1 0.033
multicellular organism growth GO:0035264 4 0.033
guanosine containing compound catabolic process GO:1901069 2 0.033
regulation of cell communication GO:0010646 232 0.033
skeletal system development GO:0001501 181 0.032
regulation of nucleocytoplasmic transport GO:0046822 2 0.031
embryonic skeletal system development GO:0048706 97 0.031
organic cyclic compound biosynthetic process GO:1901362 223 0.031
protein localization to plasma membrane GO:0072659 1 0.031
nuclear import GO:0051170 3 0.031
cell surface receptor signaling pathway GO:0007166 325 0.030
eye morphogenesis GO:0048592 144 0.030
reproductive process GO:0022414 40 0.029
neuron differentiation GO:0030182 353 0.029
gtp catabolic process GO:0006184 2 0.029
hormone secretion GO:0046879 2 0.029
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.029
regulation of translational initiation GO:0006446 1 0.029
establishment of protein localization to organelle GO:0072594 4 0.029
positive regulation of molecular function GO:0044093 33 0.029
eye development GO:0001654 277 0.028
response to abiotic stimulus GO:0009628 122 0.028
positive regulation of programmed cell death GO:0043068 29 0.028
organic acid metabolic process GO:0006082 31 0.028
protein metabolic process GO:0019538 183 0.028
mrna processing GO:0006397 14 0.028
regulation of developmental process GO:0050793 247 0.028
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.027
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.027
single fertilization GO:0007338 3 0.027
cellular protein modification process GO:0006464 100 0.027
cellular amino acid metabolic process GO:0006520 7 0.027
regulation of protein ubiquitination GO:0031396 3 0.026
central nervous system neuron differentiation GO:0021953 74 0.026
cellular ketone metabolic process GO:0042180 11 0.026
neuroblast proliferation GO:0007405 2 0.026
establishment of localization GO:0051234 244 0.026
positive regulation of macromolecule metabolic process GO:0010604 93 0.025
embryonic heart tube development GO:0035050 133 0.025
ion transport GO:0006811 114 0.025
proteasomal protein catabolic process GO:0010498 2 0.025
establishment of organelle localization GO:0051656 45 0.025
growth GO:0040007 174 0.025
translational initiation GO:0006413 3 0.025
positive regulation of cellular catabolic process GO:0031331 3 0.025
macromolecular complex subunit organization GO:0043933 74 0.025
positive regulation of map kinase activity GO:0043406 3 0.025
vasculature development GO:0001944 278 0.025
phosphate containing compound metabolic process GO:0006796 108 0.025
negative regulation of mrna processing GO:0050686 1 0.025
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.025
heart looping GO:0001947 94 0.025
cell morphogenesis GO:0000902 289 0.024
cellular response to nutrient levels GO:0031669 2 0.024
heterocycle biosynthetic process GO:0018130 215 0.024
regulation of protein modification process GO:0031399 29 0.024
hematopoietic or lymphoid organ development GO:0048534 191 0.024
axon development GO:0061564 166 0.024
optic placode formation involved in camera type eye formation GO:0046619 3 0.024
aromatic compound biosynthetic process GO:0019438 217 0.023
negative regulation of myeloid leukocyte differentiation GO:0002762 1 0.023
fertilization GO:0009566 3 0.023
regulation of cellular biosynthetic process GO:0031326 245 0.023
hematopoietic progenitor cell differentiation GO:0002244 23 0.023
protein import into nucleus GO:0006606 3 0.023
glucose homeostasis GO:0042593 1 0.023
lipid storage GO:0019915 1 0.023
immune system process GO:0002376 241 0.023
signal transduction GO:0007165 455 0.022
negative regulation of gene expression GO:0010629 65 0.022
central nervous system development GO:0007417 387 0.022
single organism nuclear import GO:1902593 3 0.022
chemical homeostasis GO:0048878 49 0.022
cell cycle GO:0007049 93 0.022
regulation of protein binding GO:0043393 3 0.021
regulation of cell shape GO:0008360 1 0.021
carboxylic acid metabolic process GO:0019752 22 0.021
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.021
pole plasm assembly GO:0007315 4 0.021
cellular nitrogen compound biosynthetic process GO:0044271 218 0.021
phosphorus metabolic process GO:0006793 109 0.021
positive regulation of translation GO:0045727 1 0.021
pancreas development GO:0031016 84 0.021
transmembrane transport GO:0055085 120 0.021
regulation of transcription dna templated GO:0006355 213 0.021
regulation of nitrogen compound metabolic process GO:0051171 251 0.021
oxoacid metabolic process GO:0043436 31 0.021
carbohydrate homeostasis GO:0033500 1 0.021
macromolecular complex assembly GO:0065003 35 0.021
positive regulation of catalytic activity GO:0043085 25 0.020
cellular response to stress GO:0033554 62 0.020
epithelial tube morphogenesis GO:0060562 148 0.020
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.020
taxis GO:0042330 109 0.020
negative regulation of signaling GO:0023057 96 0.020
protein import GO:0017038 3 0.020
small molecule metabolic process GO:0044281 77 0.020
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.020
organonitrogen compound metabolic process GO:1901564 74 0.020
proteolysis GO:0006508 38 0.020
female meiosis chromosome segregation GO:0016321 1 0.020
rna processing GO:0006396 25 0.020
establishment of rna localization GO:0051236 3 0.020
chromosome organization involved in meiosis GO:0070192 1 0.020
regulation of stem cell differentiation GO:2000736 4 0.020
type b pancreatic cell proliferation GO:0044342 1 0.019
digestive tract development GO:0048565 265 0.019
regulation of establishment of protein localization GO:0070201 4 0.019
protein stabilization GO:0050821 2 0.019
response to drug GO:0042493 3 0.019
protein targeting to nucleus GO:0044744 3 0.019
regulation of inflammatory response GO:0050727 2 0.019
behavior GO:0007610 74 0.019
regulation of metal ion transport GO:0010959 4 0.019
negative regulation of mrna metabolic process GO:1903312 3 0.019
regulation of phosphorus metabolic process GO:0051174 43 0.019
regulation of signaling GO:0023051 235 0.019
regulation of cellular protein metabolic process GO:0032268 52 0.018
regulation of localization GO:0032879 104 0.018
cellular response to chemical stimulus GO:0070887 157 0.018
cellular response to endogenous stimulus GO:0071495 68 0.018
cellular response to molecule of bacterial origin GO:0071219 3 0.018
cell part morphogenesis GO:0032990 246 0.018
neurotransmitter transport GO:0006836 2 0.018
regulation of rna metabolic process GO:0051252 224 0.018
cellular catabolic process GO:0044248 27 0.018
protein dephosphorylation GO:0006470 3 0.018
camera type eye development GO:0043010 222 0.018
anterior posterior pattern specification GO:0009952 152 0.018
sensory organ morphogenesis GO:0090596 200 0.018
ameboidal type cell migration GO:0001667 143 0.018
determination of left right symmetry GO:0007368 179 0.018
blood vessel morphogenesis GO:0048514 216 0.018
cytoskeleton dependent cytokinesis GO:0061640 3 0.018
blood vessel development GO:0001568 246 0.018
cytoskeleton organization GO:0007010 96 0.017
response to endogenous stimulus GO:0009719 83 0.017
regulation of phosphorylation GO:0042325 26 0.017
regulation of cell cycle GO:0051726 52 0.017
response to steroid hormone GO:0048545 35 0.017
negative regulation of cell death GO:0060548 60 0.017
negative regulation of catabolic process GO:0009895 3 0.017
single organism metabolic process GO:0044710 217 0.017
cellular response to organic substance GO:0071310 105 0.017
multi organism process GO:0051704 134 0.017
peptidyl threonine phosphorylation GO:0018107 1 0.017
regulation of cellular component organization GO:0051128 86 0.017
camera type eye morphogenesis GO:0048593 108 0.016
regulation of macromolecule biosynthetic process GO:0010556 225 0.016
mrna splicing via spliceosome GO:0000398 10 0.016
male meiosis GO:0007140 2 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.016
alpha amino acid metabolic process GO:1901605 3 0.016
regulation of myeloid cell differentiation GO:0045637 8 0.016
forebrain development GO:0030900 96 0.016
neurotransmitter secretion GO:0007269 2 0.016
positive regulation of biological process GO:0048518 253 0.016
regulation of erythrocyte differentiation GO:0045646 2 0.016
embryonic skeletal system morphogenesis GO:0048704 93 0.016
response to wounding GO:0009611 116 0.016
positive regulation of cell cycle GO:0045787 3 0.016
modulation by virus of host morphology or physiology GO:0019048 1 0.016
cellular response to starvation GO:0009267 1 0.016
regulation of synapse organization GO:0050807 3 0.016
cellular response to growth factor stimulus GO:0071363 39 0.016
ear development GO:0043583 127 0.015
regulation of protein phosphorylation GO:0001932 18 0.015
organelle fission GO:0048285 23 0.015
chemotaxis GO:0006935 104 0.015
segmentation GO:0035282 97 0.015
cellular response to radiation GO:0071478 4 0.015
mrna 3 end processing GO:0031124 2 0.015
meiotic spindle organization GO:0000212 1 0.015
cellular response to extracellular stimulus GO:0031668 2 0.015
skeletal system morphogenesis GO:0048705 102 0.015
female gonad development GO:0008585 4 0.015
microtubule cytoskeleton organization GO:0000226 33 0.015
meiotic cell cycle GO:0051321 5 0.015
embryonic heart tube morphogenesis GO:0003143 108 0.015
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.015
positive regulation of phosphorus metabolic process GO:0010562 21 0.015
response to light stimulus GO:0009416 46 0.015
regulation of transferase activity GO:0051338 16 0.015
somite development GO:0061053 96 0.015
cognition GO:0050890 1 0.014
regulation of cytokine production GO:0001817 3 0.014
immune system development GO:0002520 191 0.014
regulation of hydrolase activity GO:0051336 28 0.014
heart morphogenesis GO:0003007 156 0.014
neuron projection guidance GO:0097485 86 0.014
peptide transport GO:0015833 1 0.014
regulation of mapk cascade GO:0043408 14 0.014
protein complex subunit organization GO:0071822 46 0.014
determination of heart left right asymmetry GO:0061371 117 0.014
negative regulation of cellular metabolic process GO:0031324 77 0.014
spermatid differentiation GO:0048515 2 0.014
trabecula morphogenesis GO:0061383 2 0.014
optic placode formation GO:0001743 4 0.014
cellular transition metal ion homeostasis GO:0046916 3 0.014
development of primary female sexual characteristics GO:0046545 4 0.014
cartilage development GO:0051216 96 0.013
response to radiation GO:0009314 51 0.013
positive regulation of mrna processing GO:0050685 1 0.013
positive regulation of protein metabolic process GO:0051247 23 0.013
regulation of epidermis development GO:0045682 2 0.013
organic substance biosynthetic process GO:1901576 289 0.013
embryonic limb morphogenesis GO:0030326 2 0.013
negative regulation of protein complex assembly GO:0031333 1 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
tissue remodeling GO:0048771 4 0.013
biosynthetic process GO:0009058 294 0.013
cell projection organization GO:0030030 284 0.013
determination of dorsal ventral asymmetry GO:0048262 34 0.013
interaction with host GO:0051701 4 0.013
regulation of protein kinase activity GO:0045859 15 0.013
axis elongation involved in somitogenesis GO:0090245 2 0.013
intracellular mrna localization GO:0008298 1 0.013
regulation of protein transport GO:0051223 3 0.013
response to growth factor GO:0070848 39 0.013
positive regulation of cell division GO:0051781 2 0.013
neural crest formation GO:0014029 14 0.012
response to glucocorticoid GO:0051384 1 0.012
dorsal ventral pattern formation GO:0009953 125 0.012
response to nutrient GO:0007584 3 0.012
negative regulation of mitosis GO:0045839 3 0.012
positive regulation of apoptotic signaling pathway GO:2001235 1 0.012
neuron projection development GO:0031175 180 0.012
positive regulation of catabolic process GO:0009896 4 0.012
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.012
phosphorylation GO:0016310 69 0.012
macromolecule localization GO:0033036 54 0.012
hepaticobiliary system development GO:0061008 98 0.012
response to carbohydrate GO:0009743 3 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
hematopoietic stem cell differentiation GO:0060218 20 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.012
cellular localization GO:0051641 97 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
cellular component assembly involved in morphogenesis GO:0010927 107 0.012
muscle organ development GO:0007517 101 0.012
regulation of circadian rhythm GO:0042752 4 0.012
peptidyl serine phosphorylation GO:0018105 1 0.012
organic substance transport GO:0071702 58 0.012
actin polymerization or depolymerization GO:0008154 2 0.012
negative regulation of programmed cell death GO:0043069 58 0.012
gastrulation GO:0007369 208 0.012
positive regulation of secretion GO:0051047 1 0.011
regulation of gtpase activity GO:0043087 2 0.011
embryonic cranial skeleton morphogenesis GO:0048701 90 0.011
regulation of smoothened signaling pathway GO:0008589 18 0.011
regulation of kinase activity GO:0043549 15 0.011
heterocycle catabolic process GO:0046700 15 0.011
positive regulation of cell death GO:0010942 29 0.011
neural crest cell differentiation GO:0014033 72 0.011
cellular amino acid biosynthetic process GO:0008652 2 0.011
regulation of cell activation GO:0050865 1 0.011
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 1 0.011
striated muscle tissue development GO:0014706 110 0.011
membrane repolarization GO:0086009 2 0.011
stem cell development GO:0048864 82 0.011
regulation of mrna metabolic process GO:1903311 6 0.011
erk1 and erk2 cascade GO:0070371 4 0.011
single organism cellular localization GO:1902580 46 0.011
neuron development GO:0048666 262 0.011
keratinocyte differentiation GO:0030216 0 0.011
angiogenesis GO:0001525 158 0.010
response to organic cyclic compound GO:0014070 51 0.010
cell morphogenesis involved in differentiation GO:0000904 195 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
regulation of neural precursor cell proliferation GO:2000177 3 0.010
cell type specific apoptotic process GO:0097285 22 0.010
lamellipodium assembly GO:0030032 1 0.010
convergent extension involved in gastrulation GO:0060027 71 0.010
mitochondrial transport GO:0006839 2 0.010
establishment of protein localization to plasma membrane GO:0090002 1 0.010
transcription from rna polymerase iii promoter GO:0006383 1 0.010
maternal determination of anterior posterior axis embryo GO:0008358 4 0.010
cellular response to lipid GO:0071396 39 0.010
oocyte maturation GO:0001556 4 0.010

wu:fb58e05 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
nervous system disease DOID:863 0 0.020
myopathy DOID:423 0 0.015
muscular disease DOID:0080000 0 0.015
musculoskeletal system disease DOID:17 0 0.015
muscle tissue disease DOID:66 0 0.015