Danio rerio

0 known processes

wu:fb63c04

wu:fb63c04

wu:fb63c04 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
nitrogen compound metabolic process GO:0006807 319 0.228
convergent extension GO:0060026 118 0.212
regulation of mrna processing GO:0050684 3 0.190
cellular amino acid biosynthetic process GO:0008652 2 0.162
regulation of cellular amine metabolic process GO:0033238 0 0.148
morphogenesis of an epithelium GO:0002009 333 0.145
rna processing GO:0006396 25 0.142
larval development GO:0002164 2 0.141
amine metabolic process GO:0009308 2 0.137
oxoacid metabolic process GO:0043436 31 0.137
immune system process GO:0002376 241 0.134
alpha amino acid metabolic process GO:1901605 3 0.129
regulation of biological quality GO:0065008 263 0.123
regulation of hormone secretion GO:0046883 2 0.122
regulation of signaling GO:0023051 235 0.111
cellular ketone metabolic process GO:0042180 11 0.107
dicarboxylic acid metabolic process GO:0043648 1 0.105
positive regulation of transport GO:0051050 2 0.104
mrna metabolic process GO:0016071 20 0.103
positive regulation of biological process GO:0048518 253 0.102
cell surface receptor signaling pathway GO:0007166 325 0.102
cellular protein metabolic process GO:0044267 129 0.100
organic substance biosynthetic process GO:1901576 289 0.099
multi organism process GO:0051704 134 0.099
hormone transport GO:0009914 2 0.098
organic acid biosynthetic process GO:0016053 12 0.097
regulation of cellular amino acid metabolic process GO:0006521 0 0.096
hormone secretion GO:0046879 2 0.096
regulation of circadian rhythm GO:0042752 4 0.093
mesenchyme development GO:0060485 127 0.092
cellular amine metabolic process GO:0044106 2 0.091
biosynthetic process GO:0009058 294 0.089
meiotic nuclear division GO:0007126 4 0.087
cellular amino acid metabolic process GO:0006520 7 0.087
cellular macromolecule metabolic process GO:0044260 391 0.087
positive regulation of cellular process GO:0048522 201 0.085
locomotion GO:0040011 313 0.083
regulation of cell communication GO:0010646 232 0.081
phosphate containing compound metabolic process GO:0006796 108 0.081
regulation of epithelial cell proliferation GO:0050678 3 0.080
phosphorus metabolic process GO:0006793 109 0.080
regulation of mrna splicing via spliceosome GO:0048024 3 0.080
regulation of signal transduction GO:0009966 225 0.080
neuron development GO:0048666 262 0.079
central nervous system development GO:0007417 387 0.077
positive regulation of secretion GO:0051047 1 0.077
extrinsic apoptotic signaling pathway GO:0097191 3 0.074
carboxylic acid catabolic process GO:0046395 3 0.074
cell part morphogenesis GO:0032990 246 0.073
organonitrogen compound biosynthetic process GO:1901566 47 0.070
astrocyte differentiation GO:0048708 1 0.070
blood circulation GO:0008015 87 0.070
cell morphogenesis GO:0000902 289 0.068
cell projection organization GO:0030030 284 0.067
organic cyclic compound metabolic process GO:1901360 301 0.066
ameboidal type cell migration GO:0001667 143 0.064
regulation of meiotic cell cycle GO:0051445 1 0.063
cellular component morphogenesis GO:0032989 336 0.063
neuron differentiation GO:0030182 353 0.063
stem cell maintenance GO:0019827 4 0.063
organic acid metabolic process GO:0006082 31 0.062
cell fate commitment GO:0045165 99 0.062
regulation of gene expression GO:0010468 265 0.059
carboxylic acid metabolic process GO:0019752 22 0.057
regulation of cellular ketone metabolic process GO:0010565 7 0.057
positive regulation of signaling GO:0023056 56 0.055
heterocycle biosynthetic process GO:0018130 215 0.054
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.054
regulation of metabolic process GO:0019222 359 0.054
aging GO:0007568 2 0.054
small molecule metabolic process GO:0044281 77 0.052
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.052
oxidoreduction coenzyme metabolic process GO:0006733 1 0.052
alternative mrna splicing via spliceosome GO:0000380 1 0.052
gene expression GO:0010467 252 0.051
organonitrogen compound metabolic process GO:1901564 74 0.051
chemotaxis GO:0006935 104 0.050
response to light stimulus GO:0009416 46 0.048
startle response GO:0001964 4 0.048
negative regulation of cellular catabolic process GO:0031330 3 0.047
phosphorylation GO:0016310 69 0.047
cell morphogenesis involved in differentiation GO:0000904 195 0.047
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.047
peptidyl serine modification GO:0018209 2 0.046
heterocycle metabolic process GO:0046483 290 0.046
taxis GO:0042330 109 0.046
regulation of cell differentiation GO:0045595 142 0.046
positive regulation of cellular amine metabolic process GO:0033240 0 0.046
organic cyclic compound biosynthetic process GO:1901362 223 0.045
positive regulation of cell communication GO:0010647 56 0.045
response to drug GO:0042493 3 0.045
single organism transport GO:0044765 206 0.044
head development GO:0060322 303 0.044
nucleobase containing compound metabolic process GO:0006139 274 0.044
cellular nitrogen compound metabolic process GO:0034641 290 0.043
digestive tract development GO:0048565 265 0.043
cellular aromatic compound metabolic process GO:0006725 295 0.042
response to nutrient GO:0007584 3 0.042
response to external stimulus GO:0009605 264 0.041
regulation of primary metabolic process GO:0080090 311 0.041
response to organic substance GO:0010033 153 0.040
rna metabolic process GO:0016070 219 0.040
positive regulation of cell cycle GO:0045787 3 0.039
negative regulation of protein phosphorylation GO:0001933 4 0.038
signal transduction GO:0007165 455 0.038
response to uv GO:0009411 3 0.037
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.037
transport GO:0006810 220 0.037
growth GO:0040007 174 0.037
neuron projection development GO:0031175 180 0.037
cellular component movement GO:0006928 335 0.037
organic acid catabolic process GO:0016054 3 0.036
regulation of response to stimulus GO:0048583 269 0.036
positive regulation of secretion by cell GO:1903532 1 0.036
axon guidance GO:0007411 86 0.036
cell projection morphogenesis GO:0048858 244 0.035
negative regulation of gene expression GO:0010629 65 0.035
single organism biosynthetic process GO:0044711 71 0.034
regulation of nitrogen compound metabolic process GO:0051171 251 0.034
protein modification process GO:0036211 100 0.034
actin cytoskeleton organization GO:0030036 63 0.033
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.032
maintenance of location GO:0051235 4 0.032
organelle organization GO:0006996 227 0.032
multicellular organism growth GO:0035264 4 0.032
sensory organ development GO:0007423 393 0.032
neuron projection morphogenesis GO:0048812 161 0.032
protein localization to nucleus GO:0034504 3 0.031
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.031
response to wounding GO:0009611 116 0.031
neural nucleus development GO:0048857 15 0.031
determination of bilateral symmetry GO:0009855 204 0.031
peptidyl serine phosphorylation GO:0018105 1 0.030
negative regulation of cytokine production GO:0001818 1 0.030
protein import GO:0017038 3 0.030
digestive tract morphogenesis GO:0048546 231 0.030
gene silencing by rna GO:0031047 4 0.030
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.030
regulation of tube size GO:0035150 2 0.030
cellular response to chemical stimulus GO:0070887 157 0.030
regulation of macromolecule metabolic process GO:0060255 317 0.030
establishment of localization in cell GO:0051649 77 0.029
convergent extension involved in gastrulation GO:0060027 71 0.029
nucleotide metabolic process GO:0009117 28 0.029
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 4 0.029
locomotor rhythm GO:0045475 3 0.028
positive regulation of cytokine production GO:0001819 2 0.028
positive regulation of response to stimulus GO:0048584 80 0.028
response to chemical GO:0042221 320 0.028
cell cell signaling GO:0007267 52 0.028
regulation of cellular metabolic process GO:0031323 320 0.027
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.027
membrane repolarization GO:0086009 2 0.027
negative regulation of epithelial cell proliferation GO:0050680 1 0.027
regulation of neuron differentiation GO:0045664 56 0.027
response to stress GO:0006950 263 0.027
muscle structure development GO:0061061 196 0.027
compound eye development GO:0048749 2 0.027
regulation of protein binding GO:0043393 3 0.027
cellular response to nutrient levels GO:0031669 2 0.026
regulation of macromolecule biosynthetic process GO:0010556 225 0.026
response to amino acid GO:0043200 2 0.026
regulation of nucleic acid templated transcription GO:1903506 213 0.025
cellular protein modification process GO:0006464 100 0.025
regulation of metal ion transport GO:0010959 4 0.025
negative regulation of catabolic process GO:0009895 3 0.025
regulation of cytoplasmic transport GO:1903649 4 0.024
nucleocytoplasmic transport GO:0006913 4 0.024
immune system development GO:0002520 191 0.024
peptide transport GO:0015833 1 0.024
neuron projection guidance GO:0097485 86 0.024
regulation of nervous system development GO:0051960 90 0.024
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.024
cellular component biogenesis GO:0044085 178 0.024
regulation of jak stat cascade GO:0046425 3 0.024
cellular response to estrogen stimulus GO:0071391 24 0.024
actomyosin structure organization GO:0031032 53 0.023
lateral line development GO:0048882 66 0.023
macromolecule modification GO:0043412 111 0.023
regulation of multicellular organism growth GO:0040014 4 0.023
homeostatic process GO:0042592 142 0.023
multicellular organismal metabolic process GO:0044236 2 0.023
regulation of cellular protein metabolic process GO:0032268 52 0.023
behavior GO:0007610 74 0.023
protein targeting to nucleus GO:0044744 3 0.022
regulation of autophagy GO:0010506 3 0.022
heart development GO:0007507 313 0.022
leukocyte proliferation GO:0070661 1 0.022
response to dsrna GO:0043331 7 0.022
multicellular organism reproduction GO:0032504 35 0.022
generation of neurons GO:0048699 385 0.022
lipid storage GO:0019915 1 0.022
small molecule biosynthetic process GO:0044283 16 0.022
positive regulation of wound healing GO:0090303 1 0.022
secondary metabolic process GO:0019748 3 0.022
myofibril assembly GO:0030239 48 0.021
regulation of rna biosynthetic process GO:2001141 213 0.021
protein dephosphorylation GO:0006470 3 0.021
skeletal system development GO:0001501 181 0.021
positive regulation of signal transduction GO:0009967 56 0.021
regulation of nucleotide catabolic process GO:0030811 2 0.021
single organism metabolic process GO:0044710 217 0.021
autophagy GO:0006914 4 0.021
response to ketone GO:1901654 1 0.021
g protein coupled receptor signaling pathway GO:0007186 74 0.021
regulation of cellular component organization GO:0051128 86 0.020
neuromast development GO:0048884 46 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.020
multicellular organismal macromolecule metabolic process GO:0044259 2 0.020
positive regulation of catabolic process GO:0009896 4 0.020
response to organic cyclic compound GO:0014070 51 0.020
cell substrate adhesion GO:0031589 4 0.020
embryonic skeletal system development GO:0048706 97 0.020
establishment of protein localization to organelle GO:0072594 4 0.020
regulation of synapse organization GO:0050807 3 0.020
response to corticosteroid GO:0031960 1 0.019
sensory perception of chemical stimulus GO:0007606 3 0.019
heart morphogenesis GO:0003007 156 0.019
positive regulation of cytoskeleton organization GO:0051495 3 0.019
regulation of establishment of protein localization GO:0070201 4 0.019
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.019
regulation of cytokine production GO:0001817 3 0.019
nuclear import GO:0051170 3 0.019
melanin metabolic process GO:0006582 2 0.019
protein phosphorylation GO:0006468 47 0.019
regulation of inflammatory response GO:0050727 2 0.019
rna splicing GO:0008380 16 0.019
negative regulation of biological process GO:0048519 304 0.019
protein secretion GO:0009306 1 0.019
embryonic heart tube morphogenesis GO:0003143 108 0.019
regulation of reproductive process GO:2000241 4 0.018
negative regulation of kinase activity GO:0033673 4 0.018
regulation of blood vessel size GO:0050880 2 0.018
response to glucocorticoid GO:0051384 1 0.018
protein polymerization GO:0051258 4 0.018
multi organism reproductive process GO:0044703 36 0.018
positive regulation of cellular catabolic process GO:0031331 3 0.018
axonogenesis GO:0007409 152 0.018
protein metabolic process GO:0019538 183 0.018
gastrulation GO:0007369 208 0.018
cellular response to oxygen levels GO:0071453 1 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.018
midbrain development GO:0030901 28 0.018
purine containing compound biosynthetic process GO:0072522 20 0.018
neural crest cell differentiation GO:0014033 72 0.018
cellular response to lipid GO:0071396 39 0.018
regulation of translational initiation GO:0006446 1 0.017
mononuclear cell proliferation GO:0032943 1 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.017
regulation of binding GO:0051098 3 0.017
negative regulation of signaling GO:0023057 96 0.017
mesenchymal cell development GO:0014031 78 0.017
regulation of cell substrate adhesion GO:0010810 1 0.017
cellular component assembly involved in morphogenesis GO:0010927 107 0.017
regulation of protein ubiquitination GO:0031396 3 0.017
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.017
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.017
mrna processing GO:0006397 14 0.017
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.017
eye development GO:0001654 277 0.017
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.016
regulation of sequestering of calcium ion GO:0051282 4 0.016
circadian rhythm GO:0007623 19 0.016
digestive system development GO:0055123 289 0.016
morphogenesis of an epithelial fold GO:0060571 1 0.016
negative regulation of protein kinase activity GO:0006469 4 0.016
mesenchymal cell differentiation GO:0048762 87 0.016
lipid homeostasis GO:0055088 3 0.016
posterior lateral line neuromast development GO:0048919 20 0.016
negative regulation of mrna metabolic process GO:1903312 3 0.016
regulation of cell cycle GO:0051726 52 0.016
system process GO:0003008 185 0.016
calcium mediated signaling GO:0019722 2 0.016
regulation of reactive oxygen species metabolic process GO:2000377 2 0.016
regulation of response to external stimulus GO:0032101 31 0.016
response to virus GO:0009615 21 0.016
epithelial tube morphogenesis GO:0060562 148 0.015
wound healing GO:0042060 90 0.015
regulation of neurogenesis GO:0050767 87 0.015
negative regulation of metabolic process GO:0009892 86 0.015
nitric oxide metabolic process GO:0046209 2 0.015
small molecule catabolic process GO:0044282 3 0.015
regulation of protein targeting GO:1903533 2 0.015
regulation of cell development GO:0060284 100 0.015
axon development GO:0061564 166 0.015
regulation of rho protein signal transduction GO:0035023 2 0.015
transcription dna templated GO:0006351 181 0.015
canonical wnt signaling pathway GO:0060070 48 0.015
rna polyadenylation GO:0043631 2 0.015
embryonic skeletal system morphogenesis GO:0048704 93 0.015
regulation of developmental process GO:0050793 247 0.015
positive regulation of macromolecule metabolic process GO:0010604 93 0.015
cellular response to molecule of bacterial origin GO:0071219 3 0.015
regulation of biosynthetic process GO:0009889 250 0.015
cellular response to hypoxia GO:0071456 1 0.015
mrna 3 end processing GO:0031124 2 0.015
mitotic cytokinesis GO:0000281 3 0.015
sequestering of calcium ion GO:0051208 3 0.015
response to nitrogen compound GO:1901698 19 0.014
cell migration GO:0016477 237 0.014
nucleotide biosynthetic process GO:0009165 21 0.014
cellular biosynthetic process GO:0044249 286 0.014
regulation of multicellular organismal process GO:0051239 277 0.014
metal ion homeostasis GO:0055065 26 0.014
embryonic heart tube development GO:0035050 133 0.014
catabolic process GO:0009056 32 0.014
embryonic organ development GO:0048568 381 0.014
specification of symmetry GO:0009799 204 0.014
positive regulation of apoptotic process GO:0043065 29 0.014
regulation of cellular biosynthetic process GO:0031326 245 0.014
guanosine containing compound catabolic process GO:1901069 2 0.014
nuclear export GO:0051168 1 0.014
regulation of protein transport GO:0051223 3 0.014
nucleoside phosphate metabolic process GO:0006753 28 0.014
g1 s transition of mitotic cell cycle GO:0000082 1 0.014
embryo development ending in birth or egg hatching GO:0009792 271 0.014
positive regulation of apoptotic signaling pathway GO:2001235 1 0.014
gtp catabolic process GO:0006184 2 0.014
protein stabilization GO:0050821 2 0.014
adherens junction organization GO:0034332 4 0.014
cellular component assembly GO:0022607 170 0.014
regulation of protein metabolic process GO:0051246 56 0.014
sarcomere organization GO:0045214 26 0.014
neurological system process GO:0050877 62 0.014
positive regulation of cellular biosynthetic process GO:0031328 68 0.014
cell division GO:0051301 20 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.013
stem cell proliferation GO:0072089 4 0.013
cell cycle g1 s phase transition GO:0044843 1 0.013
localization of cell GO:0051674 244 0.013
nuclear transport GO:0051169 4 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.013
cytoskeleton organization GO:0007010 96 0.013
regulation of stem cell proliferation GO:0072091 2 0.013
striated muscle cell development GO:0055002 108 0.013
single organism organelle organization GO:1902589 199 0.013
camera type eye development GO:0043010 222 0.013
embryonic digestive tract development GO:0048566 4 0.013
positive regulation of translation GO:0045727 1 0.013
translational initiation GO:0006413 3 0.013
embryonic cranial skeleton morphogenesis GO:0048701 90 0.013
germ line stem cell maintenance GO:0030718 2 0.013
gtp metabolic process GO:0046039 4 0.013
lamellipodium assembly GO:0030032 1 0.013
single organism localization GO:1902578 225 0.013
negative regulation of macromolecule metabolic process GO:0010605 76 0.013
cellular response to decreased oxygen levels GO:0036294 1 0.013
phagocytosis engulfment GO:0006911 1 0.013
regulation of phosphate metabolic process GO:0019220 43 0.013
mitochondrial transport GO:0006839 2 0.012
regulation of cell activation GO:0050865 1 0.012
muscle cell development GO:0055001 115 0.012
nucleobase containing small molecule metabolic process GO:0055086 32 0.012
primary neural tube formation GO:0014020 1 0.012
cation transmembrane transport GO:0098655 65 0.012
developmental growth GO:0048589 166 0.012
ribosomal small subunit biogenesis GO:0042274 2 0.012
hemopoiesis GO:0030097 183 0.012
regulation of wound healing GO:0061041 2 0.012
calcium ion transport into cytosol GO:0060402 3 0.012
regulation of rna splicing GO:0043484 8 0.012
anatomical structure homeostasis GO:0060249 36 0.012
protein complex subunit organization GO:0071822 46 0.012
negative regulation of neurogenesis GO:0050768 20 0.012
organelle assembly GO:0070925 110 0.012
catecholamine metabolic process GO:0006584 2 0.012
lamellipodium organization GO:0097581 1 0.012
somatic stem cell maintenance GO:0035019 1 0.012
internal peptidyl lysine acetylation GO:0018393 2 0.012
muscle organ development GO:0007517 101 0.012
carboxylic acid biosynthetic process GO:0046394 12 0.012
posterior lateral line development GO:0048916 38 0.012
i kappab kinase nf kappab signaling GO:0007249 4 0.012
cytoskeleton dependent cytokinesis GO:0061640 3 0.011
organic substance transport GO:0071702 58 0.011
b cell mediated immunity GO:0019724 3 0.011
negative regulation of cellular process GO:0048523 283 0.011
positive regulation of immune system process GO:0002684 17 0.011
regulation of canonical wnt signaling pathway GO:0060828 34 0.011
response to steroid hormone GO:0048545 35 0.011
negative regulation of cell differentiation GO:0045596 46 0.011
signal transduction in absence of ligand GO:0038034 1 0.011
regulation of transport GO:0051049 45 0.011
regulation of cell shape GO:0008360 1 0.011
regulation of anatomical structure morphogenesis GO:0022603 130 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
cellular response to external stimulus GO:0071496 2 0.011
cellular response to starvation GO:0009267 1 0.011
gene silencing GO:0016458 4 0.011
b cell activation GO:0042113 2 0.011
regulation of rna metabolic process GO:0051252 224 0.011
positive regulation of multicellular organismal process GO:0051240 52 0.011
neuron projection extension GO:1990138 45 0.011
regulation of organelle organization GO:0033043 29 0.011
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.011
guanosine containing compound metabolic process GO:1901068 4 0.011
peptidyl threonine phosphorylation GO:0018107 1 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
regulation of behavior GO:0050795 24 0.011
regulation of ion transmembrane transporter activity GO:0032412 2 0.011
cellular nitrogen compound biosynthetic process GO:0044271 218 0.011
actin polymerization or depolymerization GO:0008154 2 0.011
regulation of cell growth GO:0001558 29 0.011
mechanosensory lateral line system development GO:0048881 49 0.011
regulation of gtpase activity GO:0043087 2 0.011
positive regulation of cell development GO:0010720 25 0.011
cognition GO:0050890 1 0.010
single organism nuclear import GO:1902593 3 0.010
nuclear migration GO:0007097 3 0.010
mesenchymal cell proliferation GO:0010463 1 0.010
response to hormone GO:0009725 48 0.010
positive regulation of cell activation GO:0050867 1 0.010
cell matrix adhesion GO:0007160 4 0.010
cytosolic calcium ion transport GO:0060401 3 0.010
collagen metabolic process GO:0032963 2 0.010
nucleic acid metabolic process GO:0090304 244 0.010
positive regulation of multi organism process GO:0043902 3 0.010
post embryonic organ development GO:0048569 4 0.010
cellular response to extracellular stimulus GO:0031668 2 0.010
multicellular organismal signaling GO:0035637 22 0.010
regulation of response to stress GO:0080134 36 0.010
cell proliferation GO:0008283 80 0.010
rna 3 end processing GO:0031123 2 0.010
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.010
nucleic acid templated transcription GO:0097659 181 0.010
macromolecule biosynthetic process GO:0009059 227 0.010
peptidyl lysine acetylation GO:0018394 2 0.010
cellular macromolecule biosynthetic process GO:0034645 224 0.010
modification dependent macromolecule catabolic process GO:0043632 3 0.010
negative regulation of sequestering of calcium ion GO:0051283 4 0.010

wu:fb63c04 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
hyperinsulinemic hypoglycemia DOID:13317 0 0.033
inherited metabolic disorder DOID:655 0 0.033
carbohydrate metabolic disorder DOID:2978 0 0.033
disease of metabolism DOID:0014667 0 0.033
disease of anatomical entity DOID:7 0 0.019
disease of cellular proliferation DOID:14566 0 0.010